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. This	recently	published	study	is	more	interesting	than	the	others	because
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12
,
and	people	who	are	deficient	in	these	vitamins	may	have	higher
homocysteine	levels. People	who	do	not	consume	animal-based	foods
are	at	risk	for	having	low	B
12
	levels,	and	thus	high	homocysteine	levels. However,	as	described	in	chapter	eleven,	this	has	more	to	do	with	our
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. Holick	MF. In:
	M.	E.	Shils,	J. A.	Olson,	M.	Shike	and	et	al	(eds. ),
Modern	nutrition	in	health	and	disease,	9th	ed. ,	pp. 329-345. Baltimore,
MD:	Williams	and	Wilkins,	1999. 2
. Barger-Lux	MJ,	Heaney	R,	Dowell	S,	et	al. “Vitamin	D	and	its	major
metabolites:	serum	levels	after	graded	oral	dosing	in	healthy	men.”
Osteoporosis	Int. 8	(1998):	222-230. 3
. The	biological	half-life	of	storage	vitamin	D	is	10-19	days,	the	time	it
takes	for	half	of	it	to	disappear. 4
. Colston	KW,	Berger	U,	and	Coombes	RC. “Possible	role	for	vitamin	D
in	controlling	breast	cancer	cell	proliferation.”	
Lancet
	1	(1989):	188-191. 5
. Nieves	J,	Cosman	F,	Herbert	J,	et	al. “High	prevalence	of	vitamin	D
deficiency	and	reduced	bone	mass	in	multiple	sclerosis.”	
Neurology
	44
(1994):	1687-1692. 6
. Al-Qadreh	A,	Voskaki	I,	Kassiou	C,	et	al. “Treatment	of	osteopenia	in
children	with	insulin-dependent	diabetes	mellitus:	the	effect	of	1-alpha
hydroxyvitamin	D3.”	
Eur. J.	Pediatr. 155	(1996):	15-17. 7
. Cantorna	MT,	Hayes	CE,	and	DeLuca	HF. “1,25-Dihydroxyvitamin	D
3
reversibly	blocks	the	progression	of	relapsing	encephalomyelitis,	a
model	of	multiple	sclerosis.”	
Proc. National	Acad. Sci
	93	(1996):	7861-
7864. 8
. Rozen	F,	Yang	X-F,	Huynh	H,	et	al. “Antiproliferative	action	of	vitamin
D-related	compounds	and	insulin-like	growth	factor-binding	protein	5
accumulation.”	
J.	Nat. Cancer	Inst. 89	(1997):	652-656. 9
. Cosman	F,	Nieves	J,	Komar	L,	et	al. “Fracture	history	and	bone	loss	in
patients	with	MS.”	
Neurology
	51	(1998):	1161-1165. 10
. Giovannucci	E,	Rimm	E,	Wolk	A,	et	al. “Calcium	and	fructose	intake	in
relation	to	risk	of	prostate	cancer.”	
Cancer	Res. 58	(1998):	442-447. 11
. Peehl	DM,	Krishnan	AV,	and	Feldman	D.	“Pathways	mediating	the
growth-inhibitory	action	of	vitamin	D	in	prostate	cancer.”	
J.	Nutr. 133(Suppl)	(2003):	2461S-2469S. 12
. Zella	JB,	McCary	LC,	and	DeLuca	HF. “Oral	administration	of	1,25-
dihydroxyvitamin	D
3
	completely	protects	NOD	mice	from	insulin-
dependent	diabetes	mellitus.”	
Arch. Biochem	Biophys. 417	(2003):	77-
80. 13
. Davenport	CB. “Multiple	sclerosis	from	the	standpoint	of	geographic
distribution	and	race.”	
Arch. Neurol. Pschiatry
	8	(1922):	51-58. 14
. Alter	M,	Yamoor	M,	and	Harshe	M.	“Multiple	sclerosis	and	nutrition.”Arch. Neurol. 31	(1974):	267-272. 15
. Van	der	Mei	IA,	Ponsonby	AL,	Blizzard	L,	et	al. “Regional	variation	in
multiple	sclerosis	prevalence	in	Australia	and	its	association	with
ambivalent	ultraviolet	radiaion.”	
Neuroepidemiology
	20	(2001):	168-
174. 16
. McLeod	JG,	Hammond	SR,	and	Hallpike	JF. “Epidemiology	of	multiple
sclerosis	in	Australia. With	NSW	and	SA	survey	results.”	
Med. J.	Austr
160	(1994):	117-122. 17
. Holick	MF. “Vitamin	D:	a	millenium	perspective.”	
J. Cell. Biochem. 88
(2003):	296-307. 18
. MacLaughlin	JA,	Gange	W,	Taylor	D,	et	al. “Cultured	psoriatic
fibroblasts	from	involved	and	uninvolved	sites	have	a	partial,	but	not
absolute	resistance	to	the	proliferation-inhibtion	activity	of	1,25-
dihydroxyvitamin	D
s
.”	
Proc. National	Acad. Sci
	52	(1985):	5409-5412. 19
. Goldberg	P,	Fleming	MC,	and	Picard	EH. “Multiple	sclerosis:	decreased
relapse	rate	through	dietary	supplementation	with	calcium,	magnesium
and	vitamin	D.”	
Med. Hypoth. 21	(1986):	193-200. 20
. Andjelkovic	Z,	Vojinovic	J,	Pejnovic	N,	et	al. “Disease	modifying	and
immunomodulatory	effects	of	high	dose	la(OH)D
3
	in	rheumatoid
arthritis	patients.”	
Clin. Exp. Rheumatol. 17	(1999):	453-456. 21
. Hypponen	E,	Laara	E,	Reunanen	A,	et	al. “Intake	of	vitamin	D	and	risk
of	Type	1	diabetes:	a	birth-cohort	study.”	
Lancet
	358	(2001):	1500-1503. 22
. Breslau	NA,	Brinkley	L,	Hill	KD,	et	al. “Relationship	of	animal	protein-
rich	diet	to	kidney	stone	formation	and	calcium	metabolism.”	
J.	Clin. Endocrinol. Metab. 66	(1988):	140-146. 23
. Langman	CB. “Calcitriol	metabolism	during	chronic	metabolic
acidosis.”	
Semin. Nephrol. 9	(1989):	65-71. 24
. Chan	JM,	Giovannucci	EL,	Andersson	S-O,	et	al. “Dairy	products,
calcium,	phosphorus,	vitamin	D,	and	risk	of	prostate	cancer	(Sweden).”
Cancer	Causes	and	Control
	9	(1998):	559-566. 25
. Byrne	PM,	Freaney	R,	and	McKenna	MJ. “Vitamin	D	supplementation
in	the	elderly:	review	of	safety	and	effectiveness	of	different	regimes.”
Calcified	Tissue	Int. 56	(1995):	518-520. 26
. Agranoff	BW,	and	Goldberg	D.	“Diet	and	the	geographical	distribution
of	multiple	sclerosis.”	
Lancet
	2(7888)	(November	2	1974):	1061-1066. 27
. Akerblom	HK,	Vaarala	O,	Hyoty	H,	et	al. “Environmental	factors	in	the
etiology	of	Type	1	diabetes.”	
Am. J.	Med. Genet. (Semin. Med. Genet.) 115	(2002):	18-29. 28
. Chan	JM,	Stampfer	MJ,	Ma	J,	et	al. “Insulin-like	growth	factor-I	(IGF-I)
and	IGF	binding	protein-3	as	predictors	of	advanced-stage	prostatecancer.”	
J	Natl	Cancer	Inst
	94	(2002):	1099-1109. 29
. Cohen	P,	Peehl	DM,	and	Rosenfeld	RG. “The	IGF	axis	in	the	prostate.”
Horm. Metab. res. 26	(1994):	81-84. 30
. Doi	SQ,	Rasaiah	S,	Tack	I,	et	al. “Low-protein	diet	suppresses	serum
insulin-like	growth	factor-1	and	decelerates	the	progresseion	of	growth
hormone-induced	glomerulosclerosis.”	
Am. J.	Nephrol. 21	(2001):	331-
339. 31
. Heaney	RP,	McCarron	DA,	Dawson-Hughes	B,	et	al. “Dietary	changes
favorably	affect	bond	remodeling	in	older	adults.”	
J. Am. Diet. Assoc. 99
(1999):	1228-1233. 32
. Allen	NE,	Appleby	PN,	Davey	GK,	et	al. “Hormones	and	diet:	low
insulin-like	growth	factor-I	but	normal	bioavailable	androgens	in	vegan
men.”	
Brit. J. Cancer
	83	(2000):	95-97.Index
7,12-dimethybenz(a)anthracene	(DBMA),	
65
A
academia,	
311
–
13
acrylamide,	
235
additives,	food,	
253
adverse	drug	reactions,	
16
,	
335
affluence,	diseases	of. See
	diseases	of	affluence
aflatoxin,	
5
,	
236
binding	to	DNA,	
51
–
53
children,	
36
in	corn,	
35
–
36
foci	development,	
54
,	
59
liver	cancer,	
21
,	
35
–
36
,	
49
low-protein	diet,	
53
in	peanuts	and	peanut	butter,	
35
–
36
protein,	
51
–
59
tumor	development,	
60
–
61
Agriculture,	United	States	Department	of,	
28
Alar,	
43
alcohol,	
281
alternative	medicine,	
252
,	
334
Alzheimer’s	disease,	
218
–
22
See	also
	cognitive	impairment
American	Cancer	Society,	
263
–
64
,	
267
American	Council	on	Science	and	Health	(ACSH),	
259
–
60
American	Diabetes	Association,	
152
American	Heart	Association,	
131
American	Institute	for	Cancer	Research	(AICR),	
261
–
67
American	Meat	Institute,	
290amino	acids,	
29
–
30
aminotriazole,	
44
Anderson,	James,	
151
,	
154
Angell,	Marcia,	
316
–
17
,	
333
–
34
angina,	
113
angioplasty,	
122
,	
124
animal-based	diet,	
21
,	
28
antioxidants,	
92
blood	cholesterol,	
77
–
78
,	
80
–
81
breast	cancer,	
85
–
89
,	
285
calorie	consumption,	
367
comparison	with	plant-based	diet,	
358
diabetes,	
149
–
50
dietary	fat,	
83
,	
86
government	promotion	of,	
258
heart	disease,	
117
–
19
historical	basis,	
344
–
45
hormones	(reproductive),	
88
,	
160
,	
160
–
61
IGF-1	(Insulin-like	Growth	Factor	1),	
179
large	bowel	cancer,	
170
,	
170
–
71
nutrition,	
230
,	
230
–
32
prostate	cancer,	
178
tumor	development,	
66
–
67
in	the	United	States,	
274
,	
276
–
78
vitamin	D,	
179
–
81
See	also
	dairy	foods
animal-based	protein
biomarkers,	
88
–
89
blood	cholesterol,	
80
,	
173
calcium,	
205
cancer,	
367
in	China,	
274
dietary	fat,	
276
–
78
,	
278
heart	disease,	
119
,	
120
IGF-1	(Insulin-like	Growth	Factor	1),	
367
kidney	stones,	
212
–
14
,	
213
osteoporosis,	
205
–
8
quality	of	protein,	
30
in	the	United	States,	
274
urinary	calcium,	
206
,	
214vitamin	D,	
200
,	
365
–
67
,	
366
animal	experimentation,	
45
,	
48
,	
62
–
64
,	
67
,	
351
–
52
animal	foods	industry,	
252
,	
255
–
68
See	also
	food	industry
antigens,	
185
–
86
antioxidants,	
3
,	
66
,	
92
–
93
,	
214
–
17
,	
219
–
20
,	
301
–
2
Applebaum,	Howard,	
258
apples,	
43
Appleton,	Scott,	
54
arthritis,	
199
,	
210
,	
338
artificial	sweeteners,	
44
ascorbic	acid,	
93
atherosclerosis,	
117
Atkins	Center	for	Complementary	Medicine,	
96
–
97
Atkins	Diet. See
	high-protein	diet
Atwater,	Wilbur	O.,	
28
Auburn	University,	
32
autoimmune	diseases,	
183
–
87
,	
184
,	
199
–
201
,	
237
,	
349
See	also
	diabetes;	multiple	sclerosis
Autret,	M.,	
33
B
B-cells,	
185
Bauman,	Dale,	
297
–
98
,	
300
Baxter	Healthcare	Corporation,	
328
beta-amyloid,	
219
,	
221
beta-carotene,	
93
,	
94
,	
229
biomarkers,	
21
,	
88
–
89
,	
94
,	
199
blood	cholesterol,	
77
,	
106
–
7
animal-based	protein,	
80
,	
173
breast	cancer,	
87
cancer,	
78
–
79
diabetes,	
149
–
55
,	
152
,	
154
diet	and	nutrition,	
80
–
81
heart	disease,	
114
–
15
liver	cancer,	
104
blood	sugar. See
	diabetes
BMD	(bone	mineral	density),	
210
BMI	(body	mass	index),	
100
,	
135
–
36
,	
136body	fat,	
78
body	mass	index	(BMI),	
100
,	
135
–
46
,	
136
body	size,	
102
–
4
bone	mineral	density	(BMD),	
210
bovine	serum	albumin	(BSA),	
188
BRCA	1	and	2,	
158
,	
162
breast	cancer
alcohol,	
281
biomarkers,	
21
blood	cholesterol,	
87
bone	mineral	density,	
210
casein,	
65
in	China,	
70
death	rates,	
275
diet	and	nutrition,	
65
,	
84
–
86
,	
85
–
89
,	
271
–
83
,	
285
dietary	fat,	
83
–
89
,	
84
–
86
,	
271
–
75
,	
275
estrogen,	
87
–
88
,	
160
–
61
,	
164
genetic	predisposition	to,	
158
,	
161
–
62
hormone	replacement	therapy	(HRT),	
166
–
67
hormones	(reproductive),	
3
,	
87
–
88
,	
160
,	
164
,	
167
–
68
menarche,	
87
risk	factors,	
160
,	
160
–
61
scientific	studies,	
21
,	
167
–
68
,	
272
–
85
survival	rates,	
163
tamoxifen,	
163
–
64
in	the	United	States,	
71
,	
79
See	also
	BRCA	1	and	
2
Bristol-Myers	Squibb	Company,	
328
Brokaw,	Tom,	
258
BSA	(bovine	serum	albumin),	
188
Burger	King,	
312
Burkitt,	Denis,	
89
–
91
,	
170
–
71
Bush,	George	W.,	
168
,	
175
–
76
C
Caedo,	Jose,	
36
calcitrol,	
208
calcium
animal-based	protein,	
205consumption,	
209
large	bowel	cancer,	
174
–
75
osteoporosis,	
209
vitamin	D,	
179
–
81
,	
365
–
67
,	
366
Calloway,	Doris,	
259
calorie	consumption,	
99
–
102
,	
100
,	
141
,	
367
Campbell,	Chris,	
23
,	
121
Campbell,	T.	Colin,	
xiii
–
xiv
,	
4
–
6
,	
22
,	
107
,	
157
,	
253
–
68
cancer
animal-based	protein,	
367
animal	experimentation,	
351
–
52
blood	cholesterol,	
78
–
79
body	size,	
102
–
3
casein,	
6
,	
59
,	
65
,	
294
in	China,	
70
–
71
,	
71
death	rates,	
13
,	
70
–
71
,	
71
dietary	fat,	
84
,	
271
fiber,	
91
–
92
genetic	predisposition	to,	
71
,	
85
,	
88
–
89
geographic	distribution,	
70
gluten,	
59
likelihood	of	developing,	
12
–
13
low-protein	diet,	
53
nutrition,	
50
,	
60
–
61
,	
181
–
82
,	
260
–
61
,	
271
plant-based	diet,	
348
–
49
protein,	
36
–
37
,	
51
,	
65
scientific	studies,	
53
–
67
,	
84
,	
181
–
82
,	
260
–
61
,	
351
–
52
stages	of,	
48
–
50
,	
49
tumor	development,	
61
vitamin	C,	
93
–
94
vitamins,	
269
See	also
	carcinogens;	diseases	of	affluence;	tumor	development;	specific
types	of	cancer
Cancer	Atlas	Survey
,	
70
–
71
carbohydrates,	
97
–
99
,	
149
–
55
,	
174
,	
306
–
8
See	also
	high-protein	diet
carcinogens,	
43
–
47
,	
49
,	
52
carotenoid	antioxidants,	
3
,	
66
,	
92
–
93
,	
214
–
20
,	
301
–
2
Carroll,	Ken,	
84
,	
274
–
75
caseinbreast	cancer,	
65
cancer,	
6
,	
59
,	
65
,	
294
DNA,	
65
foci	development,	
62
HBV	(hepatitis	B	virus),	
63
–
65
,	
64
heart	disease,	
294
tumor	development,	
60
–
61
See	also
	dairy	foods;	high-protein	diet;	protein
Castelli,	Bill,	
79
cataracts,	
217
Cattlemen’s	Beef	Association,	
299
,	
328
Cattlemen’s	Beef	Board,	
299
Chef	Combo’s	Fantastic	Adventures,	
293
chemicals,	environmental,	
165
–
66
Chen,	Junshi,	
67
,	
69
,	
72
,	
355
Cheney,	Dick,	
168
Cheng,	Zhiqiang,	
63
children
aflatoxin	poisoning,	
36
diabetes,	
187
–
94
obesity	in,	
135
–
37
targeted	by	food	industry,	
292
–
95
China
breast	cancer	in,	
70
calorie	consumption,	
99
–
102
cancer	in,	
70
–
71
,	
71
diet	and	nutrition,	
21
–
22
,	
74
,	
273
–
74
,	
358
HBV	(hepatitis	B	virus),	
104
liver	cancer	in,	
104
See	also
	China	Study,	The
China	Study,	The,	
7
,	
21
–
22
,	
69
–
108
,	
353
–
59
Chittenden,	Russell,	
24
cholesterol. See
	blood	cholesterol;	dietary	cholesterol
Chou	EnLai,	
69
CLA	(conjugated	linoleic	acid),	
296
–
99
Cleveland	Clinic,	
125
,	
322
–
24
,	
338
–
41
Coca-Cola,	
312
cognitive	impairment,	
3
,	
218
–
22
,	
349
Cold	is	Cool,	
293
colon	cancer. See
	large	bowel	cancercolonoscopy,	
168
,	
175
–
76
color	(of	fruits	and	vegetables),	
92
–
93
colorectal	cancer. See
	large	bowel	cancer
Committee	on	Nutrition,	United	States	Senate	Select,	
83
complex	carbohydrates,	
98
conjugated	linoleic	acid	(CLA),	
296
–
99
constitutional	nature	of	disease,	
343
–
44
corn,	
35
–
36
Cornell	University,	
32
coronary	bypass	surgery,	
122
,	
123
–
24
coronary	heart	disease.
_OceanofPDF.com_The_China_Study__The_Most_Comprehensive_St_-_T_Colin_Campbell.txt
Summarize the following text section accurately and concisely. Maintain specific details and numerical information, and use anti-repetition mechanisms:

        “Evidence	for	an
environmental	effect	in	the	aetiology	of	insulin	dependent	diabetes	in	a
transmigratory	population. ”	
Brit. Med. Journ. 304	(1992):	1020-1022. 31. Burden	AC,	Samanta	A,	and	Chaunduri	KH. “The	prevalence	and
incidence	of	insulin-dependent	diabetes	in	white	and	Indian	children	in
Leicester	city	(UK). ”	
Int. J. Diabetes	Dev. Countries
	10	(1990):	8-10. 32. Elliott	R,	and	Ong	TJ. “Nutritional	genomics.
The topic of the paper is not explicitly stated in the provided text, but it appears to be a medical research paper discussing various health-related topics.
What is the topic of the paper "Evidence for an environmental effect in the aetiology of insulin-dependent diabetes in a transmigratory population"?
The authors of this paper are Burden AC, Samanta A, and Khanna K.
Who are the authors of the paper "The prevalence and incidence of insulin-dependent diabetes in white and Indian children in Leicester city (UK)"?
There is no paper with this title in the provided text.
What is the purpose of the paper "Dietary protein, metabolic acidosis, and calcium balance"?
There is no paper with this title in the provided text.
What is the author of the paper "Dietary intake and risk of incident age-related macular degeneration"?
There is no paper with this title in the provided text.
What is the topic of the paper "Nutritional genomics"?