The following are examples of proteins that are not functional because of some problem. In which of the following examples does the problem result from damage primarily to the secondary structure of the protein?

W) The protein has been exposed to urea, which has disrupted its hydrogen bonds

X) A mutation is at the active site of a protein and the protein has lost catalytic activity

Y) A mutation is at the dimer [DY-mer] interface of a protein and prevents its dimerization

Z) A protein has been exposed to an oily chemical that disrupts its hydrophobic core
W) THE PROTEIN HAS BEEN EXPOSED TO UREA, WHICH HAS DISRUPTED ITS HYDROGEN BONDS