Phenelzine
Phenelzine, sold under the brand name Nardil, among others, is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class which is used as an antidepressant and anxiolytic. Along with tranylcypromine and isocarboxazid, phenelzine is one of the few non-selective and irreversible MAOIs still in widespread clinical use. It is taken by mouth.

In June 2020, the Therapeutic Goods Administration (TGA) reported that the availability of phenelzine was discontinued in Australia due to global issues with the manufacture of the active pharmaceutical ingredient. However, unapproved phenelzine products may be accessed through alternative pathways, such as the Special Access Scheme (SAS) administered by the TGA. In October 2020, The TGA authorized two sponsors to supply an overseas-registered brand of phenelzine in Australia. In May 2020, the Specialist Pharmacy Service in the UK reported the unavailability of phenelzine from the sole supplier. In July 2020, supplies of unlicensed phenelzine 15mg capsule specials became available for UK patients. In February 2021, Phenelzine again became available in Australia as a subsidized medication through the Pharmaceutical Benefits Scheme.
Q4914025
selective
Concept
Q427492
irreversible
Concept
Q410954
monoamine oxidase inhibitor
Concept
Q5954496
hydrazine
Concept
Q76560
antidepressant
Concept
Q62903
anxiolytic
Concept
Q420885
tranylcypromine
Concept
Q409595
isocarboxazid
Concept
Q4056087
Therapeutic Goods Administration
ORG
Q7180724
Pharmaceutical Benefits Scheme
MEDIA
Q1747559
Phenelzine
Concept
Q1747559
Phenelzine
Concept
2020-06-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
June 2020
DATE
2020-10-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
October 2020
DATE
2020-05-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
May 2020
DATE
2020-07-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
July 2020
DATE
2021-02-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
February 2021
DATE
+15^^http://www.w3.org/2001/XMLSchema#decimal
15
NUMBER
subject has role
subject has role
subclass of