CDKN2D
Cyclin-dependent kinase 4 inhibitor D is an enzyme that in humans is encoded by the "CDKN2D" gene.

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.

Note, this protein should not be confused with p19-ARF (mouse) or the human equivalent p14ARF, which are alternative products of the CDKN2A gene.
Q8047
enzyme
Concept
Q7187
gene
Concept
Q8054
protein
Concept
Q7187
gene
Concept
Q16937164
INK4 family
MISC
Q427492
inhibitor
Concept
Q14911754
CDK4
Concept
Q14911762
CDK6
Concept
Q421851
kinases
Concept
Q306383
G1
Concept
Q43054
neuronal
Concept
Q36961
spermatogenesis
UNK
Q7117832
p14ARF
Concept
Q5009957
CDKN2A
DIS
Q17860571
CDKN2D
MISC
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4
NUMBER
+2^^http://www.w3.org/2001/XMLSchema#decimal
2
NUMBER
+4^^http://www.w3.org/2001/XMLSchema#decimal
4
NUMBER
+4^^http://www.w3.org/2001/XMLSchema#decimal
4
NUMBER
+6^^http://www.w3.org/2001/XMLSchema#decimal
6
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+19^^http://www.w3.org/2001/XMLSchema#decimal
19
NUMBER
+14^^http://www.w3.org/2001/XMLSchema#decimal
14
NUMBER
+2^^http://www.w3.org/2001/XMLSchema#decimal
2
NUMBER
instance of
instance of
encodes
instance of