Genistin
Genistin is an isoflavone found in a number of dietary plants like soy and kudzu. It was first isolated in 1931 from the 90% methanol extract of a soybean meal, when it was found that hydrolysis with hydrochloric acid produced 1 mole each of genistein and glucose. Chemically it is the 7-O-beta-D-glucoside form of genistein and is the predominant form of the isoflavone naturally occurring in plants. In fact, studies in the 1970s revealed that 99% of the isoflavonoid compounds in soy are present as their glucosides. The glucosides are converted by digestive enzymes in the digestive system to exert their biological effects. Genistin is also converted to a more familiar genistein, thus, the biological activities including antiatherosclerotic, estrogenic and anticancer effects are analogous.
Q412519
isoflavone
Concept
Q11006
soy
Concept
Q15525444
kudzu
Concept
Q11006
soybean
Concept
Q103135
hydrolysis
Concept
Q2409
hydrochloric acid
Concept
Q41509
mole
Concept
Q415957
genistein
Concept
Q37525
glucose
Concept
Q137173
glucoside
Concept
Q415957
genistein
Concept
Q412519
isoflavone
Concept
Q3234924
isoflavonoid compounds
Concept
Q11006
soy
Concept
Q137173
glucoside
Concept
Q137173
glucoside
Concept
Q419557
digestive enzymes
Concept
Q9649
digestive system
LOC
Q277954
estrogenic
Concept
Q4774590
anticancer
Concept
Q5533221
Genistin
Concept
Q5533221
Genistin
Concept
1931-01-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
1931
DATE
1970-01-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
1970
DATE
+90^^http://www.w3.org/2001/XMLSchema#decimal
90
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+7^^http://www.w3.org/2001/XMLSchema#decimal
7
NUMBER
+99^^http://www.w3.org/2001/XMLSchema#decimal
99
NUMBER
found in taxon
found in taxon
found in taxon
found in taxon