KDM1A
Lysine-specific histone demethylase 1A (LSD1) also known as lysine (K)-specific demethylase 1A (KDM1A) is a protein in humans that is encoded by the KDM1A gene. LSD1 is a flavin-dependent monoamine oxidase, which can demethylate mono- and di-methylated lysines, specifically histone 3, lysines 4 and 9 (H3K4 and H3K9). This enzyme can have roles critical in embryogenesis and tissue-specific differentiation, as well as oocyte growth. KDM1A was the first histone demethylase to be discovered though more than 30 have been described.
Q8054
protein
Concept
Q7187
gene
Concept
Q174337
flavin
UNK
Q410867
monoamine oxidase
Concept
Q5255196
demethylate
UNK
Q178430
lysine
Concept
Q36293
histone
Concept
Q28962
embryogenesis
Concept
Q210861
differentiation
Concept
Q18036666
KDM1A
MISC
Q18036666
KDM1A
MISC
Q18036666
KDM1A
MISC
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+3^^http://www.w3.org/2001/XMLSchema#decimal
3
NUMBER
+4^^http://www.w3.org/2001/XMLSchema#decimal
4
NUMBER
+9^^http://www.w3.org/2001/XMLSchema#decimal
9
NUMBER
+3^^http://www.w3.org/2001/XMLSchema#decimal
3
NUMBER
+4^^http://www.w3.org/2001/XMLSchema#decimal
4
NUMBER
+3^^http://www.w3.org/2001/XMLSchema#decimal
3
NUMBER
+9^^http://www.w3.org/2001/XMLSchema#decimal
9
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+30^^http://www.w3.org/2001/XMLSchema#decimal
30
NUMBER
instance of
encodes
instance of