MT-ND4
MT-ND4 is a gene of the mitochondrial genome coding for the NADH-ubiquinone oxidoreductase chain 4 (ND4) protein. The ND4 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Variations in the MT-ND4 gene are associated with age-related macular degeneration (AMD), Leber's hereditary optic neuropathy (LHON), mesial temporal lobe epilepsy (MTLE) and cystic fibrosis.
Q7187
gene
Concept
Q27075
mitochondrial genome
MISC
Q8054
protein
Concept
Q22326958
NADH dehydrogenase (ubiquinone)
Concept
Q4896390
mitochondrial inner membrane
UNK
Q211016
electron transport chain
Concept
Q27429789
age-related macular degeneration
Concept
Q1262161
Leber's hereditary optic neuropathy
Concept
Q616667
mesial temporal lobe epilepsy
Concept
Q178194
cystic fibrosis
Concept
Q18029559
MT-ND4
Concept
Q18029559
MT-ND4
Concept
+4^^http://www.w3.org/2001/XMLSchema#decimal
4
NUMBER
+4^^http://www.w3.org/2001/XMLSchema#decimal
4
NUMBER
+4^^http://www.w3.org/2001/XMLSchema#decimal
4
NUMBER
+4^^http://www.w3.org/2001/XMLSchema#decimal
4
NUMBER
+4^^http://www.w3.org/2001/XMLSchema#decimal
4
NUMBER
instance of
genetic association
encodes
genetic association