Risperidone
Risperidone, sold under the brand name Risperdal among others, is an atypical antipsychotic used to treat schizophrenia and bipolar disorder. It is taken either by mouth or by injection into a muscle. The injectable version is long-acting and lasts for about two weeks.
Common side effects include movement problems, sleepiness, dizziness, trouble seeing, constipation, and increased weight. Serious side effects may include the potentially permanent movement disorder tardive dyskinesia, as well as neuroleptic malignant syndrome, an increased risk of suicide, and high blood sugar levels. In older people with psychosis as a result of dementia, it may increase the risk of dying. It is unknown if it is safe for use in pregnancy. Its mechanism of action is not entirely clear, but is believed to be related to its action as a dopamine antagonist and serotonin antagonist.
Study of risperidone began in the late 1980s and it was approved for sale in the United States in 1993. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2018, it was the 159th most commonly prescribed medication in the United States, with more than 3million prescriptions.
Q758295
atypical antipsychotic
Concept
Q41112
schizophrenia
Concept
Q131755
bipolar disorder
Concept
Q432083
injection into a muscle
Concept
Q1385411
movement problems
Concept
Q574801
sleepiness
Concept
Q10916362
dizziness
Concept
Q178436
constipation
Concept
Q1546328
tardive dyskinesia
Concept
Q1424956
neuroleptic malignant syndrome
Concept
Q10737
suicide
Concept
Q271993
high blood sugar levels
Concept
Q170082
psychosis
Concept
Q83030
dementia
Concept
Q11995
pregnancy
Concept
Q3271533
dopamine antagonist
Concept
Q7455047
serotonin antagonist
Concept
Q37155
World Health Organization's List of Essential Medicines
MEDIA
Q506319
generic medication
Concept
Q412443
Risperidone
Concept
1980-01-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
1980
DATE
1993-01-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
1993
DATE
2018-01-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
2018
DATE
+3^^http://www.w3.org/2001/XMLSchema#decimal
3
NUMBER
medical condition treated
medical condition treated
medical condition treated
medical condition treated
subject has role