Baclofen
Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity such as from a spinal cord injury or multiple sclerosis. It may also be used for hiccups and muscle spasms near the end of life. It is taken by mouth or by delivery into the spinal canal.
Common side effects include sleepiness, weakness, and dizziness. Serious side effects may occur if baclofen is rapidly stopped including seizures and rhabdomyolysis. Use in pregnancy is of unclear safety while use during breastfeeding is probably safe. It is believed to work by decreasing levels of certain neurotransmitters.
Baclofen was approved for medical use in the United States in 1977. It is available as a generic medication. In 2018, it was the 122nd most commonly prescribed medication in the United States, with more than 5million prescriptions.
Q12140
medication
Concept
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muscle spasticity
Concept
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spinal cord injury
Concept
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multiple sclerosis
Concept
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hiccups
Concept
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muscle spasms
Concept
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delivery into the spinal canal
Concept
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seizures
Concept
Q917069
rhabdomyolysis
Concept
Q11995
pregnancy
Concept
Q174876
breastfeeding
Concept
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neurotransmitters
Concept
Q506319
generic medication
Concept
Q413717
Baclofen
Concept
Q413717
Baclofen
Concept
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1977
DATE
2018-01-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
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DATE
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5
NUMBER
subclass of
medical condition treated
medical condition treated
medical condition treated
medical condition treated