N-acetylneuraminate synthase
In enzymology, a N-acetylneuraminate synthase () is an enzyme that catalyzes the chemical reaction

:phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O formula_1 phosphate + N-acetylneuraminate

The 3 substrates of this enzyme are phosphoenolpyruvate, N-acetyl-D-mannosamine, and H2O, whereas its two products are phosphate and N-acetylneuraminate.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming). Other names in common use include (NANA)condensing enzyme, N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating), and NeuAc synthase. This enzyme participates in aminosugars metabolism.
Q8047
enzymology
Concept
Q8047
enzyme
Concept
Q82264
catalyzes
Concept
Q36534
chemical reaction
Concept
Q12119506
substrates
Concept
Q412139
phosphoenolpyruvate
Concept
None
N-acetyl-D-mannosamine
UNK
Q283
H2O
Concept
Q542929
products
Concept
Q46220103
phosphate
Concept
Q310828
N-acetylneuraminate
Concept
Q407355
transferase
Concept
Q1255355
systematic name
UNK
Q414083
aminosugars metabolism
Concept
Q7858721
N-acetylneuraminate synthase
Concept
+2^^http://www.w3.org/2001/XMLSchema#decimal
2
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+3^^http://www.w3.org/2001/XMLSchema#decimal
3
NUMBER
+2^^http://www.w3.org/2001/XMLSchema#decimal
2
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+2^^http://www.w3.org/2001/XMLSchema#decimal
2
NUMBER
-2^^http://www.w3.org/2001/XMLSchema#decimal
-2
NUMBER
subclass of
molecular function
subclass of