Streptomycin
Streptomycin is an antibiotic medication used to treat a number of bacterial infections, including tuberculosis, "Mycobacterium avium" complex, endocarditis, brucellosis, "Burkholderia" infection, plague, tularemia, and rat bite fever. For active tuberculosis it is often given together with isoniazid, rifampicin, and pyrazinamide. It is administered by injection into a vein or muscle.
Common side effects include vertigo, vomiting, numbness of the face, fever, and rash. Use during pregnancy may result in permanent deafness in the developing baby. Use appears to be safe while breastfeeding. It is not recommended in people with myasthenia gravis or other neuromuscular disorders. Streptomycin is an aminoglycoside. It works by blocking the ability of 30S ribosomal subunits to make proteins, which results in bacterial death.
Albert Schatz first isolated streptomycin in 1943 from "Streptomyces griseus". It is on the World Health Organization's List of Essential Medicines. The World Health Organization classifies it as critically important for human medicine.
Q12187
antibiotic
Concept
Q12204
tuberculosis
Concept
Q3311330
"Mycobacterium avium" complex
Concept
Q82504
endocarditis
Concept
Q156050
brucellosis
Concept
Q135239
"Burkholderia" infection
Concept
Q133780
plague
Concept
Q153861
tularemia
Concept
Q2754970
rat bite fever
Concept
Q423169
isoniazid
Concept
Q422652
rifampicin
Concept
Q417571
pyrazinamide
Concept
Q640448
injection into a vein
Concept
Q432083
muscle
Concept
Q10686316
vertigo
Concept
Q11995
pregnancy
Concept
Q12133
deafness
Concept
Q174876
breastfeeding
Concept
Q8285
myasthenia gravis
Concept
Q2246789
neuromuscular disorders
Concept
Q28742
aminoglycoside
Concept
Q3305843
30S ribosomal subunits
Concept
Q804539
bacterial death
Concept
Q429985
Albert Schatz
PER
Q7623385
Streptomyces griseus
Concept
Q37155
World Health Organization's List of Essential Medicines
MEDIA
Q192717
Streptomycin
Concept
Q192717
Streptomycin
Concept
1943-01-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
1943
DATE
+30^^http://www.w3.org/2001/XMLSchema#decimal
30
NUMBER
subject has role
medical condition treated
medical condition treated
found in taxon