PDS5B
Sister chromatid cohesion protein PDS5 homolog B (PDS5B) is a protein that in humans is encoded by the "PDS5B" gene. It is a regulatory subunit of the Cohesin complex which mediates sister chromatid cohesion, homologous recombination and DNA looping. The core cohesin complex is formed of SMC3, SMC1, RAD21 and either SA1 or SA2. PDS5 associates with WAPL to stimulate the release of cohesin from DNA but during DNA replication PDS5 promotes acetylation of SMC3 by ESCO1 and ESCO2.
Q8054
protein
Concept
Q7187
gene
Concept
Q21103063
Cohesin
UNK
Q5399999
sister chromatid cohesion
UNK
Q25325279
DNA looping
UNK
Q15311673
SMC1
MISC
Q18031010
RAD21
MISC
Q18035179
SA1
MISC
Q18035633
SA2
MISC
Q18036695
WAPL
MISC
Q18049074
ESCO1
MISC
Q18052333
ESCO2
MISC
Q18036683
PDS5B
MISC
Q18036683
PDS5B
MISC
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
+3^^http://www.w3.org/2001/XMLSchema#decimal
3
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+21^^http://www.w3.org/2001/XMLSchema#decimal
21
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+2^^http://www.w3.org/2001/XMLSchema#decimal
2
NUMBER
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
+3^^http://www.w3.org/2001/XMLSchema#decimal
3
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+2^^http://www.w3.org/2001/XMLSchema#decimal
2
NUMBER
instance of
encodes
instance of