Hartnup disease
Hartnup disease (also known as "pellagra-like dermatosis" and "Hartnup disorder") is an autosomal recessive metabolic disorder affecting the absorption of nonpolar amino acids (particularly tryptophan that can be, in turn, converted into serotonin, melatonin, and niacin). Niacin is a precursor to nicotinamide, a necessary component of NAD+.

The causative gene, "SLC6A19", is located on chromosome 5. It is named after the British family, Hartnup, who suffered from this disease.
Q221441
pellagra
Concept
Q949302
dermatosis
Concept
Q186380
autosomal
Concept
Q3454555
recessive
Concept
Q2351083
metabolic disorder
Concept
Q8066
amino acids
Concept
Q181003
tryptophan
Concept
Q167934
serotonin
Concept
Q180912
melatonin
Concept
Q134658
niacin
Concept
Q192423
nicotinamide
Concept
Q12499775
NAD+
UNK
Q18055372
SLC6A19
Concept
Q840741
chromosome 5
MISC
Q200985
Hartnup disease
Concept
+6^^http://www.w3.org/2001/XMLSchema#decimal
6
NUMBER
+19^^http://www.w3.org/2001/XMLSchema#decimal
19
NUMBER
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
genetic association
subclass of
medical condition treated
subclass of
chromosome