Transjugular intrahepatic portosystemic shunt
Transjugular intrahepatic portosystemic shunt (TIPS or TIPSS) is an artificial channel within the liver that establishes communication between the inflow portal vein and the outflow hepatic vein. It is used to treat portal hypertension (which is often due to liver cirrhosis) which frequently leads to intestinal bleeding, life-threatening esophageal bleeding (esophageal varices) and the buildup of fluid within the abdomen (ascites).

An interventional radiologist creates the shunt using an image-guided endovascular (via the blood vessels) approach, with the jugular vein as the usual entry site.

The procedure was first described by Josef Rösch in 1969 at Oregon Health and Science University. It was first used in a human patient by Dr. Ronald Colapinto, of the University of Toronto, in 1982, but did not become reproducibly successful until the development of endovascular stents in 1985. In 1988 the first successful TIPS was realized by M. Rössle, G.M. Richter, G. Nöldge and J. Palmaz at the University of Freiburg. The procedure has since become widely accepted as the preferred method for treating portal hypertension that is refractory to medical therapy, replacing the surgical portocaval shunt in that role.
Q9368
liver
Concept
Q464543
portal vein
Concept
Q1578686
hepatic vein
Concept
Q124604
portal hypertension
Concept
Q147778
liver cirrhosis
Concept
Q298278
esophageal varices
Concept
Q193889
ascites
Concept
Q426449
interventional radiologist
Concept
Q1498222
endovascular
Concept
Q988343
blood vessel
Concept
Q749592
jugular vein
Concept
Q16090106
Josef Rösch
PER
Q282097
Oregon Health and Science University
LOC
Q180865
University of Toronto
LOC
Q153987
University of Freiburg
ORG
Q1438498
Transjugular intrahepatic portosystemic shunt
UNK
1969-01-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
1969
DATE
1982-01-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
1982
DATE
1985-01-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
1985
DATE
1988-01-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
1988
DATE
has cause
symptoms and signs
has cause