PRDX5
Peroxiredoxin-5 (PRDX5), mitochondrial is a protein that in humans is encoded by the "PRDX5" gene, located on chromosome 11. 
This gene encodes a member of the six-member peroxiredoxin family of antioxidant enzymes. Like the other five members, PRDX5 is widely expressed in tissues but differs by its large subcellular distribution. In human cells, it has been shown that PRDX5 can be localized to mitochondria, peroxisomes, the cytosol, and the nucleus. Human PRDX5 is identified by virtue of the sequence homologies to yeast peroxisomal antioxidant enzyme PMP20.

Biochemically, PRDX5 is a peroxidase that can use cytosolic or mitochondrial thioredoxins to reduce alkyl hydroperoxides or peroxynitrite with high rate constants in the 106 to 107 M−1s−1 range, whereas its reaction with hydrogen peroxide is more modest, in the 105 M−1s−1 range. So far, PRDX5 has been shown to be a cytoprotective antioxidant enzyme that inhibits endogenous or exogenous peroxide accumulation.
Q8054
protein
Concept
Q7187
gene
Concept
Q419462
peroxiredoxin
Concept
Q133948
antioxidant
Concept
Q39572
mitochondria
Concept
Q138639
peroxisome
Concept
Q220599
cytosol
Concept
Q40260
nucleus
Concept
Q253817
alkyl hydroperoxides
Concept
Q419130
peroxynitrite
UNK
Q107429
peroxide
Concept
Q18037720
PRDX5
MISC
Q18037720
PRDX5
MISC
Q18037720
PRDX5
MISC
Q18037720
PRDX5
MISC
Q18037720
PRDX5
MISC
Q18037720
PRDX5
MISC
Q18037720
PRDX5
MISC
-5^^http://www.w3.org/2001/XMLSchema#decimal
-5
NUMBER
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
+11^^http://www.w3.org/2001/XMLSchema#decimal
11
NUMBER
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
+20^^http://www.w3.org/2001/XMLSchema#decimal
20
NUMBER
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
instance of
encodes
instance of