SUFU
Suppressor of fused homolog is a protein that in humans is encoded by the "SUFU" gene.
In molecular biology, the protein domain suppressor of fused protein (Sufu) has an important role in the cell. The Sufu is important in negatively regulating an important signalling pathway in the cell, the Hedgehog signalling pathway (HH). This particular pathway is crucial in embryonic development. There are several homologues of Sufu, found in a wide variety of organisms. 

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Q8054
protein
Concept
Q7187
gene
Concept
Q7202
molecular biology
Concept
Q898273
protein domain
Concept
Q8054
protein
Concept
Q7868
cell
Concept
Q411391
regulating
Concept
Q210973
signalling pathway
Concept
Q14859918
Hedgehog signalling pathway
UNK
Q28962
embryonic development
Concept
Q224180
homologues
Concept
Q7239
organisms
Concept
Q17145556
SUFU
Concept
instance of
encodes
part of