Vimentin
Vimentin is a structural protein that in humans is encoded by the "VIM" gene. Its name comes from the Latin "vimentum" which refers to an array of flexible rods.

Vimentin is a type III intermediate filament (IF) protein that is expressed in mesenchymal cells. IF proteins are found in all animal cells as well as bacteria. Intermediate filaments, along with tubulin-based microtubules and actin-based microfilaments, comprises the cytoskeleton. All IF proteins are expressed in a highly developmentally-regulated fashion; vimentin is the major cytoskeletal component of mesenchymal cells. Because of this, vimentin is often used as a marker of mesenchymally-derived cells or cells undergoing an epithelial-to-mesenchymal transition (EMT) during both normal development and metastatic progression.
Q8054
structural protein
Concept
Q7187
gene
Concept
Q397
Latin
Concept
None
type III intermediate filament (IF) protein
UNK
Q32838
mesenchymal
Concept
Q421987
IF proteins
Concept
Q729
animal cells
Concept
Q10876
bacteria
Concept
Q422492
tubulin
Concept
Q189933
microtubules
Concept
Q185269
actin
Concept
Q329638
microfilament
UNK
Q154626
cytoskeleton
Concept
Q32838
mesenchymal
Concept
Q74419
epithelial-to-mesenchymal transition
UNK
Q181876
metastatic
Concept
Q411624
Vimentin
Concept
Q411624
Vimentin
Concept
instance of
encodes