五大湖地域
250px|thumb|北アメリカの五大湖地域（赤色）
五大湖地域（）は、北アメリカのカナダ＝アメリカ合衆国国境を挿み、五大湖の周辺に広がる地域のことである。カナダ側ではオンタリオ州が含まれ、アメリカ合衆国側ではイリノイ州、インディアナ州、ミシガン州、ミネソタ州、ニューヨーク州、オハイオ州、ペンシルベニア州、ウィスコンシン州が含まれる。この地域は歴史、経済、文化で独特のものを形成している。この地域の一部は五大湖メガロポリスと考えられることもある。

アメリカ合衆国域内各州とカナダのオンタリオ州およびケベック州を加えて認定した五大湖委員会は2国に跨る政体であり、五大湖と周辺水域および帯水層の水資源を守り保護するために特定の権限を持っている。この委員会の権限はカナダ、アメリカ合衆国両国政府によって確認されている。

五大湖地域は、北のハドソン湾に流れる水系、西のミシシッピ川水系、東と南のオハイオ川水系に囲まれ、五大湖を取り囲む比較的狭い流域である五大湖盆地の地質学的形成、すなわち五大湖からその名前がある。東方にはセントローレンス川、リシュリュー川、ハドソン川、モホーク川、サスケハナ川が大西洋に向かうアーチ状の水域を形成している。

五大湖地域は五大湖盆地という地理区分とは別に、五大湖水域に跨り、1つ以上の湖に接するアメリカ合衆国各州とカナダのオンタリオ州によって定義される地方レベル政体の単位を定義している。
250px|thumb|北アメリカの五大湖地域（赤色）
UNK
Q49
北アメリカ
LOC
Q119515
カナダ＝アメリカ合衆国国境
Concept
Q7347
五大湖
MEDIA
Q16
カナダ
LOC
Q1904
オンタリオ州
LOC
Q30
アメリカ合衆国
LOC
Q1204
イリノイ州
LOC
Q1415
インディアナ州
LOC
Q1166
ミシガン州
LOC
Q1527
ミネソタ州
LOC
Q1384
ニューヨーク州
LOC
Q1397
オハイオ州
LOC
Q1400
ペンシルベニア州
LOC
Q1537
ウィスコンシン州
LOC
Q176
ケベック州
LOC
Q3040
ハドソン湾
LOC
Q1497
ミシシッピ川
LOC
Q4915
オハイオ川
LOC
Q134750
セントローレンス川
LOC
Q1809877
リシュリュー川
LOC
Q3140
ハドソン川
LOC
Q1345896
モホーク川
LOC
Q27538
サスケハナ川
LOC
Q97
大西洋
LOC
Q1548416
五大湖地域
Concept
Q1548416
五大湖地域
Concept
Q1548416
五大湖地域
Concept
Q1548416
五大湖地域
Concept
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