ERG5
ERG5 or Sterol 22-desaturase is a cytochrome P450 enzyme in the ergosterol biosynthesis pathway of fungi "Saccharomyces cerevisiae" (Baker's yeast, a model organism), with the CYP Symbol CYP61A1. CYP61A1 is one of only three P450 enzyme found in baker's yeast, the other two are CYP51F1 and CYP56A1. The ortholog in "Schizosaccharomyces pombe" (fission yeast, the second sequenced model fungi), was named CYP61A3 for historical reasons, and is only one of two P450 enzyme found with CYP51F1. ERG5 catalyzes the C22-C23 double bond formation on the sterol side chain of ergostatrienol to convert it into ergostatetraenol, then the C24 double bond of ergostatetrenol will be hydrogenation reduced into ergosterol by ERG4.
Q407693
cytochrome P450
Concept
Q8047
enzyme
Concept
Q764
fungi
Concept
Q719725
Saccharomyces cerevisiae
Concept
Q27547483
CYP51F1
MISC
Q27550925
CYP56A1
MISC
Q2236682
Schizosaccharomyces pombe
Concept
Q213907
model fungi
Concept
Q4639583
ergostatrienol
UNK
None
ergostatetraenol
UNK
Q214166
hydrogenation
Concept
Q143263
ergosterol
Concept
Q27543731
ERG4
UNK
Q27542758
ERG5
UNK
Q27542758
ERG5
UNK
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
+22^^http://www.w3.org/2001/XMLSchema#decimal
22
NUMBER
+450^^http://www.w3.org/2001/XMLSchema#decimal
450
NUMBER
+61^^http://www.w3.org/2001/XMLSchema#decimal
61
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+61^^http://www.w3.org/2001/XMLSchema#decimal
61
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+450^^http://www.w3.org/2001/XMLSchema#decimal
450
NUMBER
+51^^http://www.w3.org/2001/XMLSchema#decimal
51
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+56^^http://www.w3.org/2001/XMLSchema#decimal
56
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+61^^http://www.w3.org/2001/XMLSchema#decimal
61
NUMBER
+3^^http://www.w3.org/2001/XMLSchema#decimal
3
NUMBER
+450^^http://www.w3.org/2001/XMLSchema#decimal
450
NUMBER
+51^^http://www.w3.org/2001/XMLSchema#decimal
51
NUMBER
+1^^http://www.w3.org/2001/XMLSchema#decimal
1
NUMBER
+5^^http://www.w3.org/2001/XMLSchema#decimal
5
NUMBER
+22^^http://www.w3.org/2001/XMLSchema#decimal
22
NUMBER
+23^^http://www.w3.org/2001/XMLSchema#decimal
23
NUMBER
+24^^http://www.w3.org/2001/XMLSchema#decimal
24
NUMBER
+4^^http://www.w3.org/2001/XMLSchema#decimal
4
NUMBER
instance of