2020–21 Iowa State Cyclones men's basketball team
The 2020–21 Iowa State Cyclones men's basketball team represented Iowa State University during the 2020–21 NCAA Division I men's basketball season. The Cyclones were coached by Steve Prohm, who was in his sixth season at Iowa State (and, as it turned out, his last). They played their home games at Hilton Coliseum in Ames, Iowa as members of the Big 12 Conference.

The Cyclones would suffer through a COVID-19-plagued 2–22 record, including an 0–18 mark in Big 12 play, the first team to go winless through the Big 12 since TCU in 2014. Following the end of the season, ISU athletic director Jamie Pollard announced that the school and Prohm had parted ways.
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Iowa State University
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2020–21 NCAA Division I men's basketball season
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Steve Prohm
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Hilton Coliseum
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Ames, Iowa
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Big 12 Conference
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COVID-19
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TCU in 2014
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Jamie Pollard
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2020–21 Iowa State Cyclones men's basketball team
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located in the administrative territorial entity