Hypermobility spectrum disorder
Hypermobility spectrum disorder (HSD), related to earlier diagnoses such as hypermobility syndrome (HMS), and joint hypermobility syndrome (JHS) is a heritable connective tissue disorder that affects joints and ligaments. Different forms and sub-types have been distinguished, but it does not include asymptomatic joint hypermobility, sometimes known as double-jointedness.

Symptoms can include the inability to walk properly or for long distances, and pain in affected areas. Some people with HSD have hypersensitive nerves and a weaker immune system. It can also cause severe fatigue and some cases cause depressive episodes. It is somewhat similar to other genetic connective tissue disorders such as Ehlers–Danlos syndromes.
Q1779300
connective tissue disorder
Concept
Q1641042
double-jointedness
Concept
Q9620
nerve
Concept
Q1059
immune system
Concept
Q9690
fatigue
Concept
Q42844
depressive episodes
Concept
Q200779
genetic
Concept
Q1141499
Ehlers–Danlos syndromes
Concept
Q1110590
Hypermobility spectrum disorder
Concept
subclass of