Ophiuchus Supercluster eruption
According to NASA and others, the Ophiuchus Supercluster eruption was the biggest AGN outburst seen in the observable universe since the MS 0735+74 outburst.
This extremely powerful eruption occurred in the Ophiuchus Supercluster, which is located about 390 million light-years from Earth. A paper describing these results appeared online on 27 February 2020 in The Astrophysical Journal, and a preprint is available on arXiv. This eruption was caused by a supermassive black hole spraying out jets of extremely active particles over hundreds of millions of years. The total energy which was slowly released over hundreds of millions of years is estimated to be 5 × 1061 erg, or 5 × 1054 J, but it's likely an underestimate, given uncertainty of cavities's size and difficulties of part of them to be discovered.
Furthermore, the cavity produced by the outburst is so big that would be possible to put 15 galaxies of Milky Way's dimensions in a row.

The authors of this paper are Simona Giancintucci (Naval Research Laboratory, Washington, DC), Maxim Markevitch (Goddard Space Flight Center, Greenbelt, Maryland), Melanie Johnston-Hollitt (International Centre for Radio Astronomy, Australia), Daniel Wik (University of Utah), Qian Wang (University of Utah), and Tracy Clarke (Naval Research Laboratory). The 2016 paper by Norbert Werner et al. was published in the Monthly Notices of the Royal Astronomical Society.

This observation is a result of collaboration among various space-based and Earth-based observatories including the Hubble Space Telescope, the Chandra X-ray Observatory, ESA’s XMM Newton X-ray space observatory and radio data from the Murchison Widefield Array (MWA) in Australia and the Giant Metrewave Radio Telescope (GMRT) in India.
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