1813–1814 Malta plague epidemic
The 1813–1814 Malta plague epidemic () was the last major outbreak of plague on the islands of Malta and Gozo. It occurred between March 1813 and January 1814 on Malta and between February and May 1814 on Gozo, and the epidemic was officially declared to be over in September 1814. It resulted in approximately 4500 deaths, which was about 5% of the islands' population.

The plague outbreak had begun in Constantinople in 1812 and it spread to other parts of the Ottoman Empire including Egypt. The disease was imported to Malta from Alexandria on board the brigantine "San Nicola" in late March 1813. Some of its crew members had contracted the disease and died, and although the vessel and crew were quarantined, the disease spread to the local population since infected cargo from the vessel was stolen and sold in Valletta. The disease appeared in the city in mid-April, and the outbreak was severe by mid-May.

The British colonial government took strict measures in order to contain the plague, although this was done too late to prevent the outbreak from spreading in its early stages. The urban area around the Grand Harbour was isolated from the rest of the island, and settlements with high mortality rates were cordoned off. Violations of these regulations were met with harsh penalties including death, and several people were executed for concealing their infection. The outbreak was particularly severe in the capital Valletta and its suburb Floriana, and in the villages of Birkirkara, Qormi and Żebbuġ.

The epidemic began to subside by late 1813 and it was believed to be over by January 1814. However, the disease was inadvertently introduced to Gozo through contaminated clothes in February, and another outbreak occurred in the village of Xagħra. Containment measures were imposed immediately, limiting the spread and resulting in a much lower mortality rate in Gozo.
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Xagħra
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1813–1814 Malta plague epidemic
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