Perindopril
Perindopril is a medication used to treat high blood pressure, heart failure, or stable coronary artery disease. 

As a long-acting ACE inhibitor, it works by relaxing blood vessels and decreasing blood volume. As a prodrug, perindopril is hydrolyzed to its active metabolite, perindoprilat, in the liver. It was patented in 1980 and approved for medical use in 1988.

Perindopril is taken in the form of perindopril arginine (trade names include Coversyl, Coversum) or perindopril erbumine (Aceon). Both forms are therapeutically equivalent and interchangeable, but the dose prescribed to achieve the same effect differs between the two forms. It is also often combined with another medication, sometimes in the same tablet (see #Combinations below).
Q12140
medication
Concept
Q41861
high blood pressure
Concept
Q181754
heart failure
Concept
Q844935
coronary artery disease
Concept
Q288280
ACE inhibitor
Concept
Q988343
blood vessels
Concept
Q1896673
blood volume
Concept
Q603741
prodrug
Concept
Q407595
metabolite
Concept
Q173670
arginine
Concept
Q288188
erbumine
UNK
None
#Combinations
UNK
Q277785
Perindopril
Concept
Q277785
Perindopril
Concept
1980-01-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
1980
DATE
1988-01-01T00:00:00Z^^http://www.w3.org/2001/XMLSchema#dateTime
1988
DATE
instance of
medical condition treated
medical condition treated
subject has role