u.s. democratic senator claire mccaskill thursday expand investigation cause opioid crisis plague country seek information four drugmakers three drug distributors top-ranking democrat senate homeland security governmental affairs committee focus distribution opioids efforts company make report investigate diversion drug illicit use investigation come time lawmakers regulators take step combat epidemic opioid addiction 91 americans die everyday result overdose accord u.s. center disease control prevention mccaskill request document information opioid manufacturers mallinckrodt plc endo international plc teva pharmaceutical allergan plc march mccaskill ask johnson johnson mylan nv purdue pharma insys therapeutics inc depomed inc internal estimate risk abuse addiction overdose opioids senator also send request mckesson corp amerisourcebergen corp cardinal health inc focus distribution opioid products mccaskill also request information compensation provide way derive revenue profitability target sales opioid products appreciate senator mccaskill inquiry look forward thoughtfully answer question mckesson spokeswoman say email add link sale control substances incentive compensation company executives amerisourcebergen say would respond letter senator add provide daily report regulators quantity type receive pharmacy every single order control substances distribute endo say receive letter would provide senator request information allergan say work senator office provide request information company also say two brand opioid products norco kadian account 0.1 percent less opioids prescribe unite state israel-based teva email say commit appropriate use opioids responsible pain management mallinckrodt confirm receipt senator mccaskill request information add previously meet provide information staff would continue work office company note manufacture generic non-promoted brand opioids cardinal health decline comment u.s. senator expand opioid probe distributors drugmakers