new york front-runner donald trump show sign tighten grip republican u.s. presidential nomination wednesday chief rival ted cruz acknowledge hope wrest control contest convention trump deliver crush defeat cruz tuesday new york republican nominate contest democratic front-runner hillary clinton break rival bernie sanders string state victories definitive win rebound defeat wisconsin two weeks ago trump set another big night april 26 northeast u.s. state pennsylvania connecticut rhode island delaware maryland hold primaries ted cruz mathematically win race trump tweet wednesday spoiler never nice thing beat hillary trump 69 predict amaze weeks ahead campaign cruz news conference sideline republican national committee meet hollywood florida say neither trump amass 1,237 delegate need win nomination without contest convention cleveland start july 18 clear today head toward contest convention nobody able reach 1,237 go reach 1,237 donald trump go reach 1,237 say cruz u.s. senator texas new york boost trump delegate tally 845 cruz 559 kasich 147 accord associate press next tuesday contest offer 172 delegate republicans clinton lead trump -poll trump new york billionaire clinton former u.s. secretary state go secure respective party nominations reuters/ipsos national opinion poll show clinton sizeable lead nov. election hold today late poll likely general election voters 45 percent say would support clinton 35 percent would support trump two run april 15-19 poll survey 1,334 people credibility interval 3.1 percentage point former reality tv star trump adopt measure tone recent days appear try heal wound inflict campaign alarm many republican establishment send campaign advisers party meet florida begin wednesday two issue leave republicans trump get 50 percent delegate prior cleveland close new york give nice boost take weeks know answer say ari fleischer white house spokesman president george w. bush cruz 45 come third new york ohio governor john kasich 63 long-shot candidate seek use second-place show new york proof emerge trump central challenger trump least 89 delegate new york kasich get least three accord ap cruz win prompt trump adviser sarah huckabee sanders urge cnn wednesday get way math delegate count make impossible prevail win clinton 68 make nearly impossible sanders 74 overtake command lead delegate need secure nomination clinton clinch least 175 291 new york delegate sanders least 106 accord ap u.s. senator vermont sanders vow fight democrats nominate convention philadelphia start july 25. democratic strategist jim manley say clinton delicate task try attract sanders supporters draw leftist campaign promise switch focus task beat eventual republican nominee run risk go far leave go upset independents others go need general manley say trump tighten grip u.s. republican nomination