text: describe tandem mass spectrometry and its advantage? describe tandem mass spectrometry and what advatage it provides? and what is another name for non-watson crick pairing? mass spectrometry is an analytical technique used to measure the mass-to-charge ratio of ions. it is most generally used to find the composition of a physical sample by generating a mass spectrum representing the masses of sample components.  tandem mass spectrometry involves multiple steps of mass selection or analysis, usually separated by some form of fragmentation. a tandem mass spectrometer is one capable of multiple rounds of mass spectrometry. for example, one mass analyzer can isolate one peptide from many entering a mass spectrometer. a second mass analyzer then stabilizes the peptide ions while they collide with a gas, causing them to fragment by collision-induced dissociation (cid). a third mass analyzer then catalogs the fragments produced from the peptides.