text: how to cure multiple personality disorder?   did is usually caused by some sort of early trauma, usually severe, sustained trauma like abuse, living on the streets, being a refugee, etc. memories and experiences that are too much for a young child are then "given" to a separate personality, who is strong enough to handle them.   when a psychiatrist deals with a person with more than one personality, he usually has to start out dealing with each one separately... the goal is to get them "talking" to each other, and cooperating. ultimately, they may re-integrate into a single personality again. before this can happen, the original trauma usually has to be dealt with and accepted as part of the person's past.  medicines can help--depression, ptsd, and anxiety are very common comorbids to did, and these often respond to various antidepressants, tranquilizers, and antipsychotics. however, most of the work is done by the patient in counseling; the medicines in this case are helpers but not the main treatment.