text: if the relatives (such as a sister) of the nurofibromatosis victim had children would they possibly have nf? like if a sister had a brother with neurofibromatosis would her kids possibly inherit the nf from their uncle? nf is inherited in the mendelian manner so if the unaffected sister is a carrier her children have a 1 in 4 chance of being affected. the sister has a 1 in 4 chance of being a carrier for the faulty gene