text: most runs scored in a major league baseball game?   most runs scored in a game (since 1900):  one team: 29. (tie) boston red sox vs. st. louis browns, june 8, 1950 chicago white sox vs. oakland a's, april 23, 1955  two teams: 49. chicago cubs beat the philadelphia phillies, 26–23 on aug. 25, 1922, at wrigley field (then cubs park) in chicago.