text: my ribs/ sides are very painful. is this possibly a side effect from glucophange/ metformin? i was diagnosed diabetic type ii (not a bad one though) in feb. since then i've started yoga, a new diet, work out and hike. i've lost 35 lbs and two sizes. now my ribcage and the spot under my left ribcage is very painful,  sometimes the right side hurts too. i've also had a few bouts with thrush. i've been x-rayed, tested, and had ultra sounds. the doc doesn't know whats causing it. i have not been in an accident that would have cracked a rib.my kidneys, appendix and gall bladder are fine and we've ruled out a workout injury.  is this a wacky side effect to the medication? have any of you experienced this? i am at my wits end, this has been on going for over a month. my mom had a condition when she was younger where the tissue between her rib cage got inflamed...she had to take a steroid to make it go away...i forgot the condition, but maybe you can ask your doctor about "inflamed tissue between the ribs..." hope this helps!