text: is too much dietary supplements bad for you? i take many dietary supplements such as vitamin c, zinc, etc. if i keep on taking these supplements, is there a way where my body can form a tolerance to these? yes, taking too much of the fat soluble vitamins: a, d, e, and k can harm your body.  most of the water soluble vitamins will be taken out of your body by your kidneys.  this does not mean that they cannot harm you, only that it takes a large amount of these vitamins to do so.  zinc (like most metals) can give you an upset stomach, nausea and vomiting.  tolerance to vitamins? not the way you are thinking, but your body can begin to manufacture/convert less of the vitamins it normally does by being overloaded with an abundance of them.