text: does anyone have pmdd? about a year ago my obgyn diagnosed me with pmdd and put me on prozac for 2 months, my husband said that i got worse on the prozac. is anyone else dealing with this? have you gotten worse or better with/ without medication? yeah, i've had difficulties with the meds too.  try a different one.  there are so many of them.  wellbutrin, paxil and lexapro are supposed to be good.  a friend of mine takes zoloft and is doing better.