text: what's the best way to battle depression? my husband was deployed in the army since january, and i've noticed my depression become a lot worse.  i was taking 100 mg of zoloft before he left, but it doesn't seem to help.  what can i do?  i have no friends or family were i live.  the only thing that's keeping me going is school and my pets.  what can i do? please listen......  i am a psychology major and depressed.  i take zoloft.  academically all scientists know that depression stems from a serotonin loss.  it is biological.  my professor in anatomy said if she hadn't taken an anti-depressant, she would be dead.  both her brothers killed themselves.  yes, it may be genetic, not always.  the brothers didn't buy into the "taking pills" theory.  meanwhile, she took the recommended dosage and went on to get her ph.d.  i take 100 mg. of zoloft every day .  when i become more symptomatic, i increase it to 200 mg. a day.  i fluctuate.  wouldn't you rather be happy?  don't listen to all the people who have uneducated opinions.  they are dangerous.  angelof2worlds's answer is based on opinion.  look at the facts and talk to people who walk the walk.    i hope it all works out for you, darling girl.