text: is there an anti depressant that does not cause sexual dysfunction,such as inabilty to stay erect & ejaculate? i once tried wellbutrin and it did not work for me.i'm having diffuculty maintaining an erection and reaching orgasm. i'm currently taking effexor odd, because wellbutrin is well known for its lesser tendency to have sexual side effects. perhaps your dosage wasn't sufficient enough to control the depression (which, in turn, would have a significant effect on sexual function).  still, it is true that you need to find the right one that works for you. just remember to make sure your doctor knows the effectiveness and side effects of your medications so he can work with you.