text: treatment of large bun blisters on feet?   do you mean bunions? those can be very painful, and they need to be surgically fixed(http://orthopedics.about.com/cs/toeproblems/a/bunions_2.htm).... if you mean a burn blister, (if it is bad, seek medical attention)   1. clean the skin around the blister.      2.   place a doughnut-shaped piece of moleskin over the blister. this will keep pressure off it.      3.   try to avoid popping the blister unless it's in an especially awkward place, such as the bottom of your foot. the blister provides a sterile environment for the skin underneath. breaking it makes the area more susceptible to infection.        5.   avoid peeling any skin off the blister; this can lead to an infection and delay healing.      6.   cover the exposed blister with a thin layer of antibiotic ointment and dry sterile gauze.      7.   change the gauze regularly and watch for signs of infection, such as pus or redness.