text: how can i tell if my physiology makes me liable to become a drug addict if i ever tried dugs? straightforward question. i am not saying i plan to do drugs, so no preaching. short of some very unreliable and very expensive genetic testing - which may or may not provide a reliable answer, the best answer i can give you is to know yourself and your family history.  your odds of addition increase if you have any family member with an addiction problem. your odds increase if you suffer from addiction to any other substance, item, relationship etc (meaning you have a so called "addictive personality"). your odds also drastically increase if you are hanging around with others involved in such things, as familiarity breeds laxity in this case. another physiological indication is if you have any problems with tolerance with any prescription meds such as pain killers - whether they dont affect you very much or kick your butt a lot  (both increasing your odds). also, if there is a class of painkiller you dont respond to well - such as the 'caine family (lidocaine, lanocaine, supracaine - usually used by dentists) you can know something about your response to particular drug families (in this case, cocaine).   i'm sorry this answer isnt more precise - but there is not a precise answer to your question.