text: question about multiple system atrophy? my dad was just recently diagnosed with multiple system atrophy and going down hill fast at his last doctors appointment they said there are parts deep in his brain not functioning at all, over the past year he has gone through extensive therapy for his balance, gross motor skills and speech which at the time seemed to help but has gotten worse over time again now the doctors said we play the waiting game, wait to see if cancer shows up or just wait for him to get worse. my question is does anyone know about this disease or if there is anything we can do except wait. thanks multiple system atrophy, or msa, has no cure. it is a degenerative disorder of the brain that is neither hereditary nor due to another condition. if he has a firm diagnosis then encourage him to get his affairs in order, and spend time with each other. i'm sorry.