What is the deadliest mosquito-born disease?
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Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of "Plasmodium" that cause malaria in humans. It is transmitted through the bite of a female "Anopheles" mosquito. It is responsible for roughly 50% of all malaria cases. It causes the disease's most dangerous form called falciparum malaria. It is therefore regarded as the deadliest parasite in humans, causing 435,000 deaths in 2017. It is also associated with the development of blood cancer (Burkitt's lymphoma) and is classified as Group 2A carcinogen.
Plasmodium falciparum
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Mosquito-borne diseases are currently most prevalent in East Africa, Latin America,  Southeast Asia, and India; however, emergence of vector-borne diseases in Europe have recently been observed. A weighted risk analysis demonstrated associations to climate for 49% of infectious diseases in Europe including all transmission routes. One statistical model predicts by 2030, the climate of southern Great Britain will be climatically-suitable for malaria transmission "Plasmodium vivax" malaria for 2 months of the year. By 2080 it is predicted that the same will be true for southern Scotland.
Mosquito
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Plasmodium vivax is a protozoal parasite and a human pathogen. This parasite is the most frequent and widely distributed cause of recurring (Benign tertian) malaria, "P. vivax" is one of the five species of malaria parasites that commonly infect humans. Although it is less virulent than "Plasmodium falciparum", the deadliest of the five human malaria parasites, "P. vivax" malaria infections can lead to severe disease and death, often due to splenomegaly (a pathologically enlarged spleen). "P. vivax" is carried by the female "Anopheles" mosquito; the males do not bite.
Plasmodium vivax
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Mosquito-borne diseases or mosquito-borne illnesses are diseases caused by bacteria, viruses or parasites transmitted by mosquitoes. They can transmit disease without being affected themselves. Nearly 700 million people get a mosquito-borne illness each year resulting in over one million deaths.
Mosquito-borne disease
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Mosquito-borne diseases, such as dengue fever and malaria, typically affect third world countries and areas with tropical climates. Mosquito vectors are sensitive to climate changes and tend to follow seasonal patterns. Between years there are often dramatic shifts in incidence rates. The occurrence of this phenomenon in endemic areas makes mosquito-borne viruses difficult to treat.
Mosquito-borne disease
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Other viral diseases like epidemic polyarthritis, Rift Valley fever, Ross River fever, St. Louis encephalitis, West Nile fever, Japanese encephalitis, La Crosse encephalitis and several other encephalitic diseases are carried by several different mosquitoes. Eastern equine encephalitis (EEE) and Western equine encephalitis (WEE) occurs in the United States where it causes disease in humans, horses, and some bird species. Because of the high mortality rate, EEE and WEE are regarded as two of the most serious mosquito-borne diseases in the United States. Symptoms range from mild flu-like illness to encephalitis, coma and death.
Mosquito-borne disease
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Mosquitoes carrying such arboviruses stay healthy because their immune systems recognizes the virions as foreign particles and "chop off" the virus's genetic coding, rendering it inert. Human infection with a mosquito-borne virus occurs when a female mosquito bites someone while its immune system is still in the process of destroying the virus's harmful coding. It is not completely known how mosquitoes handle eukaryotic parasites to carry them without being harmed. Data has shown that the malaria parasite "Plasmodium falciparum" alters the mosquito vector's feeding behavior by increasing frequency of biting in infected mosquitoes, thus increasing the chance of transmitting the parasite.
Mosquito-borne disease
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From the success seen in Australia, the researchers were able to begin operating in more threatened portions of the world. The Eliminate Dengue program spread to 10 countries throughout Asia, Latin America, and the Western Pacific blooming into the non-profit organization, World Mosquito Program, as of September 2017. They still use the same technique of infecting wild populations of "Ae. aegypti" as they did in Australia, but this time their target disease has shifted to include Zika and chikungunya on top of dengue. Although not alone in their efforts to use "Wolbachia-"infected mosquitoes to reduce mosquito-borne disease, the World Mosquito Program method is praised for being self-sustaining in that it causes permanent phenotype change rather than reducing mosquito populations through cytoplasmic incompatibility through male-only dispersal.
Mosquito-borne disease
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There is a re-emergence of mosquito vector viruses (arthropod-borne viruses) called arboviruses carried by the "Aedes aegypti" mosquito. Examples are the Zika virus, chikungunya virus, yellow fever and dengue fever. The re-emergence of the viruses has been at a faster rate, and over a wider geographic area, than in the past. The rapid re-emergence is due to expanding global transportation networks, the mosquito's increasing ability to adapt to urban settings, the disruption of traditional land use and the inability to control expanding mosquito populations. Like malaria, other arboviruses do not have a vaccine. The only exception is yellow fever. Prevention is focused on reducing the adult mosquito populations, controlling mosquito larvae and protecting individuals from mosquito bites. Depending on the mosquito vector, and the affected community, a variety of prevention methods may be deployed at one time.
Mosquito-borne disease
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Mosquito-borne diseases are probably the greatest threat to humans as they include malaria, elephantiasis, Rift Valley fever, yellow fever, and dengue fever. Studies are showing higher prevalence of these diseases in areas that have experienced extreme flooding and drought. Flooding creates more standing water for mosquitoes to breed; as well, shown that these vectors are able to feed more and grow faster in warmer climates. As the climate warms over the oceans and coastal regions, warmer temperatures are also creeping up to higher elevations allowing mosquitoes to survive in areas they had never been able to before. As the climate continues to warm there is a risk that malaria will make a return to the developed world.
Effects of global warming on human health