the results of these studies have indicated that the decrease in the activity of the hepatic mixed-function oxidase enzyme system and the concentration of cytochrome p-450 seen on incubation of carbon disulfide ( cs2 ) with rat liver microsomes in the presence of nadph is the result of the binding of the sulfur atom released in the mixed-function oxidase catalyzed metabolism of cs2 to carbonyl sulfide ( cos ) .
C0010762
cytochrome p-450
C0025519
metabolism