the findings obtained during an electron-microscopic examination of the spermatozoa at the beginning of the process included visible changes in the ultrastructure of the flagellum , particularly its middle piece ( deformed shape , incomplete set of axial filaments , vacuolization of the flagellum , abnormal arrangement of the mitochondrial spiral ) , numerous abnormities of the external cytoplasmic membrane and invagination , vacuolization , and abnormal density of nucleoplasm .
C0026237
mitochondrial
C0010834
cytoplasmic