it is suggested that the secretion of large amounts of both the high molecular weight component and proinsulin relative to that of insulin might be due , in part at least , to the inability of the tumoral cells to prevent the release of newly synthetized hormonal peptides , leading to the depletion of the tissue in hormonal products , as judged by both immunological and ultrastructural criteria .
C0033362
proinsulin
C0021641
insulin