although it has not been possible to ascertain whether the amino groups involved in the tnbs effect belong to the membrane phospholipids or to the atpase proteins , it appears that such groups play an essential role in the hydrolytic activity of the divalent cation-dependent atpases , either by affecting the enzymes ' microenvironment or by being directly involved in the enzymes'catalytic mechanism .
C0001473
atpase
C0020291
hydrolytic