histologic studies of the skeletal system showed cartilaginous and bony fusion of the spinous processes ( cases 1 , 2 ) , fusion of epiphyseal cartilages of distal humerus and proximal ulna , a poorly developed joint space , an abnormal growth plate , and weak safranin staining of the resting cartilages ( cases 1 , 2 ) .
C0037253
skeletal system
C0007301
cartilages