dexamethasone increases the specific activity of alkaline phosphatase in a time- and dose-dependent fashion ( maximum 14-fold induction at 10 ( -6 ) m , ic50 = 10 ( -8 ) m ) , and this induction can be completely inhibited by simultaneous incubation with picomolar concentrations of recombinant human il-1 alpha or il-1 beta .
C0086418
human
C0021753
il-1 beta