pretreatment of pituitary cells for 6 h with gnrh ( 10 ( -11 ) - 10 ( -6 ) m ) caused a biphasic change in gnrh receptor number [ the maximum binding ( bmax ) for 125i-buserelin binding was increased by 10 ( -10 ) m gnrh and reduced by 10 ( -7 ) and 10 ( -6 ) m gnrh ] and caused desensitization ( pretreatment with 10 ( -9 ) - 10 ( -6 ) m gnrh reduced the proportion of cellular lh released in a subsequent challenge with gnrh ) .
C0006456
buserelin
C0023610
gnrh