however , we observed in the drug-treated cell membranes , an increase in activity of nucleoside diphosphate kinase , an additional factor which has been proposed to play a role in regulating adenylate cyclase by replenishing gtp near the guanine nucleotide binding site ( kimura , n. , and shimada , n. ( 1983 ) j. biol . chem . 258 , 2278-2283 ) .
C0018353
gtp
C0018328
guanine nucleotide