it is reported on a mental retarded female , observed from 3-33 years of age , which demonstrated even in adulthood with long lasting shrill crying the clinical leading symptom of lejeune syndrome and further typical symptoms with inhibition of physical maturation , important delayed motoric and mental development , microcephaly resp . characteristic craniofacial dysmorphia , anomalies of extremities , muscular hypotonia and susceptibility to infection .
C0025958
microcephaly
C0376634
craniofacial dysmorphia