our experiments demonstrate , contrary to previous observations , that myotube cultures synthesize and accumulate laminin , and further , that the differentiation of proliferating myoblasts to multinucleated myotubes is accompanied by increased laminin synthesis , by secretion of laminin into the medium , and by the deposition of laminin into an extracellular matrix on the myotube surface .
C0022984
laminin
C0015350
extracellular matrix