objective measurements from exercise treadmill tests showed significant reduction in peak heart rate from 130 to 103 bpm , systolic blood pressure from 197 to 167 mm hg , rate pressure product ( from 25 to 18 bpm-mm hg x 1000 ) , and st depression in patients receiving acebutolol compared with those receiving placebo .
C0428977
reduction
C0000946
acebutolol