evidence for the clonal nature of chronic myelogenous leukemia ( cml ) has been obtained primarily from studies of black females expressing polymorphic glucose-6-phosphate dehydrogenase ( g6pd ) isoenzymes where , instead of the heterozygous pattern normally found as a result of random x chromosome inactivation , exclusive expression of only one g6pd allele has been demonstrated in leukemic cell populations .
C0023473
chronic myelogenous leukemia
C1517806
leukemic cell