here we report the construction of a full-length cdna for the human mdr1 gene and show that this reconstructed cdna , when inserted into a retroviral expression vector containing the long terminal repeats of moloney leukemia virus or harvey sarcoma virus , functions in mouse nih 3t3 and human kb cells to confer the complete multidrug-resistance phenotype .
C0376622
mdr1
C0242640
multidrug-resistance