termination of pregnancy was performed in 3 patients on the basis of cytogenetic abnormalities ( 47 , xxy , 47 , xxx , 47 , xy 21+ ) : in 2 patients with anencephalic fetuses on the basis of alpha-fetoprotein and ultrasound investigations , and 1 patient with fetal hurler 's syndrome .
C0002210
alpha-fetoprotein
C0015965
fetal