the ability of zinc to specifically modulate postsynaptic neuronal responses to excitatory amino acid transmitters , reducing n-methyl-to-aspartate receptor-mediated excitation while often increasing quisqualate receptor-mediated excitation , is proposed to underlie its normal function at central excitatory synapses and furthermore could be relevant to neuronal cell loss in certain disease states .
C1516988
excitatory synapses
C0007634
cell