superfusion of isolated ventricles with ringer solution containing exogenous , lipid-soluble derivatives of 3 ' 5'-cyclic amp and 3 ' 5'-cyclic gmp affects both the rate of decline of the isometric twitch and the steady-state tension ultimately reached : thus , 8-bromo-3 ' 5'-cyclic gmp accelerates the decline in contractility and depresses the steady-state level , whereas dibutyryl 3 ' 5'-cyclic amp delays the development of hypodynamic depression , and elevates the final twitch tension .
C0001455
cyclic amp
C0012054
dibutyryl