hemeproteins , like cytochrome c ( 12,500 m.w . ; karnovsky and rice , 1969 ) and myoglobin ( 17,816 m.w . ; anderson , 1972 ; simionescu et al. , 1973 ) are advantageous over the true peroxidases with larger molecular weights ( e.g . horseradish peroxidase , ca . 40,000 m.w ) as ultrastructural probes in that they do not elicit vascular leakage in the inflammatory response ( cotran and karnovsky , 1967 ) and are relatively nontoxic immunologically inert substances .
C0031179
peroxidases
C0019941
horseradish peroxidase