the safety and efficacy of sustained-release diltiazem 120 to 180 mg , 2 times a day , were compared with hydrochlorothiazide 25 to 50 mg , 2 times a day , and the combination of diltiazem and hydrochlorothiazide in 56 patients with mild to moderate hypertension ( supine diastolic blood pressure between 95 and 114 mm hg ) using a placebo-controlled , parallel-design protocol .
C0012373
diltiazem
C0020538
hypertension