carboxypeptidase g2 ( cpg2 ) , an enzyme produced by pseudomonas strain rs-16 , degrades folates as well as methotrexate and other folic acid analogs such as aminopterin and dichloromethotrexate , but not the `` '' non-classical '' '' folate antagonist trimetrexate ( tmtx ) .
C0025677
methotrexate
C0002583
aminopterin