evidence about the relationship of these prominent ige responses in patients with onchocerciasis to the onchocercal skin disease that manifests as pruritus and papular eruptions is conflicting , but in a guinea pig model of ocular pathology induced by onchocerca microfilariae evidence for the pathogenetic importance of ige and immediate hypersensitivity is much less equivocal .
C0037274
skin disease
C0033774
pruritus