the same intrarenal feed-back mechanism , normally adapting the glomerular blood supply to the resorptive capacity of the proximal-tubular epithelium ( mediation via the juxta-glomerular apparatus ) , is responsible for the gfr- and rpf-raising effect of exogenous l-thyroxine in the intact kidney as well as in acute renal failure : both sodium reabsorption and sodium filtration are accelerated. -- the special conditions under which l-thyroxine interferes with the pathogenetic process of acute renal failure , the latter being characterised by the critical insufficiency of tubular sodium reabsorption and therefore by preglomerular arterial constriction , is discussed on the basis of a new hypothesis concerning the thyrogenic nephrotropic effects in general .
C0022646
kidney
C0022660
acute renal failure