the highly purified extended chimeric protein ( t-pa/scu-pa-e ) was found to have similar specific activity on fibrin film ( 65,000 iu/mg ) , kinetic constants for the activation of plasminogen ( km = 1 microm , k2 = 0.0026 s-1 ) , fibrin affinity ( 50 % binding at a fibrin concentration of 3.3 g/liter ) , and fibrin specificity of clot lysis in a plasma environment ( 50 % lysis in 2 h with 8 nm of the chimer ) as the previously characterized chimeric protein ( t-pa/scu-pa-s ) .
C0015982
fibrin
C0032105
plasma