by classifying each tumor cell in one of four stages of necrotic alteration ( stage 1 : intact cell , stage 2 : slightly condensed nucleus and shrunken cytoplasm , stage 3 : necrotic cell with still visible nuclear membrane , stage 4 : cell debris ) we arrived at an index for necrobiotic alterations of the 18 adenomas .
C0010834
cytoplasm
C0007603
cell