feeding of vitamin k-deficient diets or fasting produced vitamin k deficient syndromes in both conventional and germ-free male rats in 3 days , increasing prothrombin time ( pt ) , activated partial thromboplastin time ( aptt ) , plasma and liver descarboxyprothrombin ( pivka ) levels and liver gamma-glutamylcarboxylase activities , but decreasing plasma clotting factor vii and prothrombin levels .
C0023884
liver
C0015502
clotting factor vii