although the reverse hemolytic plaque assay demonstrated immunoglobin-releasing cells to be present on the surface of the lower respiratory tract of normal subjects , and present in increased numbers in patients with ipf or sarcoidosis , these plaque-forming cells were not actively synthesizing immunoglobulins , since preincubation of lavage cells in order to remove immunoglobulin bound to the surface of the cells reduced the number of plaque-forming cells , and inhibition of protein synthesis by cycloheximide did not further reduce the number of plaque-forming cells .
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surface of
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the