since some monoclonal or polyclonal human serum antibodies of rheumatoid arthritis ( ra ) or mixed connective tissue disease ( mctd ) have been reported to recognize shared epitopes of denatured igg and dna-histone ( nucleosomes ) , this mrp-2 monoclonal antibody with the similar activity derived from a lupus-prone mouse will be useful for the studies on the etiology of autoantibodies associated with ra , mctd and systemic lupus erythematosus ( sle ) .
C0019652
histone
C0028623
nucleosomes