although 3,3',4,4'-tetrachlorobiphenyl specifically induced certain drug-metabolizing enzyme activities , e.g . aryl hydrocarbon hydroxylase and udp-glucuronosyltransferase ( toward 4-nitrophenol ) , no highly significant correlations were found among the vitamin a levels and drug-metabolizing enzyme activities in the liver ( aminopyrine n-demethylase , aryl hydrocarbon hydroxylase , aldrin epoxidase , microsomal epoxide hydrolase , udp-glucuronosyltransferase toward 4-nitrophenol , glutathione transferase toward 1-chloro-2,4-dinitrobenzene and cytochrome p-450 content ) as determined by multiple linear regression analysis .
C0003927
aryl hydrocarbon
C0010762
cytochrome p-450