in this work we fractionated cm-nb by size exclusion high performance liquid chromatography , and separated two active principles ( 28,000 and 62,000 daltons ) each or a combination of the 28,000 and 62,000 dalton fractions showed a differential inhibitory effect on dna synthesis or clonal growth of the three human lung cell lines : the normal diploid fibroblast wi38 cells were less susceptible than their simian virus 40-transformed va13 cells and carcinoma a549 cells .
C0016030
fibroblast
C0007634
cells