we recorded in blood the circadian rhythmicity of melatonin , acth and cortisol and the excretion of melatonin , cortisol and porter-silber chromogens in urine before , during and after the administration of 750 mg metyrapone every 4 h during 24 h in two healthy volunteers and in two patients with asymptomatic , moderate hyperparathyroidism and a prolactin-secreting microadenoma , respectively .
C0033371
prolactin
C1327616
secreting