these proteins possess two contiguous regions of sequence identity : a c-terminal catalytic domain of 260 residues with homology to other tyrosine-specific and serine-threonine-specific protein kinases , and a unique domain of approximately 100 residues which is located n terminal to the kinase region and is absent from kinases that span the plasma membrane .
C0072402
serine-threonine
C0031727
kinases