diethylstilbestrol ( des ) and 17beta-estradiol treatment in female rats significantly decreased the number of dopamine binding sites ( b max ) from 85 +/- 3.9 fmol/mg protein in untreated rats to 9.2 +/- 1.2 and 8.2 +/- 2.8 fmol/mg protein in des and 17beta-estradiol-treated rats , respectively , while the binding affinities ( kd ) did not change significantly .
C1335665
protein
C0034693
rats