the soluble fraction obtained after lysis of digested nuclei with edta ( 1 mmol/l ) , the s2 fraction , represented approximately 17 % of the original nuclear dna , and showed properties consistent with transcriptional activity , i.e . enrichment in nascent rna , non-histone protein and endogenous rna polymerase b activity as well as depletion in histones .
C0007610
nuclei
C0019652
histones