the cardiovascular effects of the selective 5 ht2-serotonergic antagonist ketanserin ( cumulative doses of 0.01 , 0.04 , 0.16 , 0.64 and 2.5 mg.kg-1 i.v . at 30 min intervals ) were investigated in closed-chest , anesthetized dogs with spontaneously beating hearts ( n = 7 ) and in dogs with a fixed heart rate ( n = 7 ) .
C0007226
cardiovascular
C0018787
hearts