apart from non-specific alterations also known to occur in hepatocytes in hepatitis a and b -- such as proliferation of membranes of smooth endoplasmic reticulum , formation of membrane-bound cytoplasmic vacuoles containing electron-dense material , and accumulation of distorted peroxisomes -- unique cytoplasmic changes were observed that have not previously been described in man .
C0007603
membrane
C0010834
cytoplasmic