a comparison with the results of an earlier study , in which hydrochlorothiazide was given without amiloride , showed that the intracellular potassium depletion and the increase in intracellular sodium concentration , observed with the benzothiazide diuretic , could be fully prevented by simultaneous administration of amiloride .
C0020621
potassium depletion
C0002502
amiloride