we demonstrated recently that purified preparations of gs , the stimulatory g protein of adenylyl cyclase , can stabilize ca2+ channels in inside-out cardiac ventricle membrane patches stimulated prior to excision by the beta-adrenergic agonist isoprenaline or by the dihydropyridine agonist bay k 8644 and that such preparations of gs can restore activity to spontaneously inactivated cardiac ca2+ channels incorporated into planar lipid bilayers ( yatani , a. , codina , j. , reeves , j.p. , birnbaumer , l. , and brown , a.m. ( 1987 ) science 238 , 1288-1292 ) .
C0018827
cardiac
C0018787
cardiac