the minimal neurotoxic concentrations ( mtcs ) of phenobarbital in both plasma and brain evaluated by a rotorod test were 50 % lower ( p less than 0.05 ) in old ( 24-months-old ) mice compared with the respective values in young ( 6-months-old ) mice , while 12-months values were the highest of the three groups .
C0086045
concentrations
C0006104
brain