the methanol-extracted , nonprotein chromophore of the protein antibiotic neocarzinostatin ( ncs ) , which possesses the full in vitro and in vivo deoxyribonucleic acid ( dna ) strand-breaking activities and the ability to inhibit dna synthesis and growth in hela cells of the holoantibiotic , is much more labile to inactivation by heat , 2-mercaptoethanol , long-wavelength uv light , and ph values above 4.8 .
C0012854
deoxyribonucleic acid
C0598312
dna synthesis