tunicamycin-treated b16-f1 and b16-f10 cells lost their lung colonization abilities when injected intravenously into c57bl/6 mice , concomitant with lowered rates of adhesion to endothelial cell monolayers , endothelial extracellular matrix ( basal lamina ) , and polyvinyl-immobilized fibronectin in vitro , suggesting that this drug inhibits experimental metastasis by modifying the surface glycoproteins involved in determining the adhesive properties of malignant cells .
C0225336
endothelial cell
C0014257
endothelial