using the same approach but with a more sensitive detection system ( alkaline phosphatase instead of peroxidase ) , we did not detect polypeptide species related to rat uricase in human fetal or adult liver samples , which indicates that during hominoid evolution , the mutational event responsible for the loss of uricase activity in humans precluded formation of a translatable uricase mrna .
C0027021
peroxidase
C0086418
humans