membrane receptors incubated in the presence of spermine at concentrations inhibitory to human 125i-fsh binding ( 0.01-0.04 m ) resulted in an 8-50 % decrease in the apparent fsh receptor concentration and a 10-65 % decrease in the affinity constant as determined by computerized analysis of the isothermic ligand-binding data .
C0034806
fsh
C1517880
ligand-binding