in isolated rat pancreatic islets , the tumor-promoting agent 12-o-tetradecanoylphorbol-13-acetate ( tpa ) , when used in the 2.10 ( -9 ) to 2.10 ( -7 ) m range , was found to stimulate insulin release both in the absence and presence of glucose .
C0022131
pancreatic islets
C0021641
insulin