the chain of chemical reactions elicited by antigen-antibody interaction does not end with the release of srs-a and the other mediators ( histamine , eosinophil chemotactic factor of anaphylaxis , ecf-a ) , on the contrary , these mediators especially srs-a induce the release of prostaglandins of type e ( pge1 and pge2 ) which produce bronchodilatation and inhibit the release of srs-a itself , perhaps being a selfregulating mechanism .
C0033559
prostaglandins
C0012472
pge2