this agent selectively induces the synthesis of some specific cytochrome p-450 isoenzymes at the expense of others , so that the metabolism of benzo [ a ] pyrene is shifted from the route leading to the highly mutagenic 7,8-dihydrodiol 9,10-epoxides to the route leading to the much less mutagenic 4,5-epoxide .
C0010762
cytochrome p-450
C0025519
metabolism