whereas thrombin was found to be an activator of phospholipase c as judged by a rapid increase in the formation of inositol triphosphate , inositol biphosphate and a massive accumulation of inositol phosphate when 20 mm licl was present as an inhibitor of inositol mono phosphatases , basic fgf failed to induce the breakdown of the polyphosphoinositides in quiescent pc12 cells to any appreciable levels , however , a simultaneous increase in the level of diacylglycerol was observed . b fgf also failed to stimulate protein kinase c which is believed to be activated by diacylglycerol .
C0016026
fgf
C0380603
b fgf