the combination of alpha-tocopherol with lidocaine fully prevented the decrease in n-dimethylation of amidopyrine and cytochrome p-450 and b5 concentration , and the development of destructive alterations of cytoplasmic reticulum in the unaffected rat hepatocytes . alpha-tocopherol and lidocaine pretreatment was effective for the retention of the depression of microsomal monooxygenases by phenobarbital in remote periods after acute hepatic ischemia .
C0010762
cytochrome p-450
C0003927
microsomal monooxygenases