the addition of low levels of a wide variety of inducers of a diverse chemical nature , dimethylformamide ( dmf ) , retinoic acid ( ra ) , actinomycin d ( act-d ) or hypoxanthine ( hpx ) prior to the addition of 8-bromo-cyclic adenosine 3'-5 ' monophosphate ( 8-br-camp ) , cholera toxin ( ct ) or the phosphodiesterase inhibitor isobutylmethylxanthine ( ibmx ) results in marked potentiation of differentiation of both hl60 and rdfd cells as manifested by the acquisition of the antigen okm-1 , the ability to reduce nitroblue tetrazolium or expression of the chemotactic receptor .
C0007589
differentiation
C0007634
cells