cotransfection of cos1 cells with the 'antisense ' gene and a plasmid containing an sv40 origin of replication resulted in a substantial transient inhibition of sv40-replicon function when compared to control determinations ( 50 % to nearly complete inhibition of large t-antigen dependent dna replication for 18-36 h ) .
C0007634
cells
C0242961
origin of replication