between april 1988 and august 1989 , 30 melanoma patients were entered in a multicentre phase ii study of dacarbazine ( dtic ) 850 mg/m2 i.v . bolus on day 1 , and recombinant interleukin-2 ( ril-2 ) ( cetus ) 18 x 10 ( 6 ) iu/m2/day i.v . continuous infusion on days 4-9 .
C0025202
patients
C0010927
dtic