in the present study , it is revealed that the immunoreactivities of ca isozymes increased in oncocytes as the number of mitochondria increased , suggesting that oncocytes have a high level of carbonic anhydrase for catalyzing the hydration of an increased amount of carbon dioxide generated chiefly via oxidative metabolism by mitochondria , the number of which is notably increased compensatorily for their deficient coupling of oxidative phosphorylation or other metabolic anomaly .
C0282636
oxidative metabolism
C0026237
mitochondria