the second step is to be performed in case of a past history of bleeding , but normal first-step laboratory screening and is aimed at detecting the less frequent abnormalities of hemostasis such as factor xiii , antiplasmin , platelet factor 3 , von willebrand factor , tissue plasminogen activator and dysfibrinogenemia , to which the first-step screening tests are not sensitive .
C0019080
bleeding
C0042971
von