in the present study 55 patients with refractory acute myeloid leukemia ( aml ) ( n = 44 ) and acute lymphoblastic leukemia ( all ) ( n = 11 ) were treated with high-dose cytosine arabinoside ( hd-ara-c ) and mitoxantrone ( ham ) to assess the toxicity and antileukemic activity of the two-drug combination .
C0023467
acute myeloid leukemia
C0026259
mitoxantrone