experimental thyrotoxicosis was produced in guinea pigs by daily intraperitoneal injection of 0.7 mg/kg thyroxine ( t4 ) or 0.15 mg/kg triiodothyronine ( t3 ) , as shown by an increase of pbi over 50 gamma percent , weight reduction of 20 -- 30 percent , and increase in heart rate of 30 -- 50 percent .
C0040156
thyrotoxicosis
C0040165
thyroxine