second-generation therapies , cop-blam ( cyclophosphamide , vincristine , prednisone , bleomycin , doxorubicin , procarbazine ) , promace-mopp ( prednisone , methotrexate , doxorubicin , cyclophosphamide , etoposide , mechlorethamine , vincristine , procarbazine , prednisone ) , m-bacod ( methotrexate , bleomycin , doxorubicin , cyclophosphamide , vincristine , dexamethasone ) , and m-bacod ( same as m-bacod , but with a moderate dose of methotrexate and modified leucovorin given on days 8 and 15 instead of just day 10 ) were characterized by an increasing number of drugs , more frequent administration of myelosuppressive agents , and flexible dose schedules .
C0084185
promace-mopp
C0013089
doxorubicin