using this procedure the following common disposition parameters were obtained for both routes of administration : t1/2 alpha = 0.1 h , t1/2 beta = 2.1 h , t1/2 gamma = 9.8 h ( harmonic means derived from individualized fits ) , vc = 0.9 +/- 0.4 l/kg , vss = 5.2 +/- 2.4 l/kg , cltot = 11.5 +/- 1.8 ml/min/kg .
C0184661
procedure
C0013153
routes of administration