using both saponin-permeabilized n1e-115 cells and microsomal membranes from cells , this report describes the effectiveness of both inositol 1,4,5-trisphosphate ( ip3 ) and guanine nucleotides in mediating ca2+ release from this internal organelle , believed to be endoplasmic reticulum .
C0007634
cells
C0014239
endoplasmic reticulum