our results demonstrate a lack of inhibition of gtp gamma s ( 40 microm ) -induced 5ht secretion by pma in permeabilised platelets , despite significant inhibition ( 70 % ) of pa formation , suggesting that apart from the diacylglycerol pathway of secretion which may be common to thrombin and gtp analogues , secretion induced by physiological agonists such as thrombin may involve another mechanism that is inhibitable by phorbol esters .
C0079469
gtp gamma s
C0018353
gtp