the morphological counterpart is an hypertrophy of the nucleoli and spiralization of nucleolonema , an increase of the number of ribosomes with the persistence of a specific organization for each stage of development , then the proliferation of the granular endoplasmic reticulum and the modification of the predominant shape of mitochondria , which becomes annular , their outer surface being largely increased .
C0035553
ribosomes
C0230779
granular endoplasmic reticulum