beta-secondary equilibrium isotope effects for reduction of ketones by dpnh ( cyclohexanone-2,2,6,6-d4 , 0.82 ; acetone-d6 , 0.78 ; pyruvate-d3 , 0.83 ; alpha-ketoglutarate-3,3-d2 reduced to glutamate , 0.898 ; oxaloacetate-3,3-d2 , 0.877 ; oxaloacetate-3r-d , 0.945 ) give an average value of 0.946/d , with deuterium becoming enriched in the alcohol or amino acid with respect to the ketone .
C0001002
acetone
C0022634
ketone