this sequence of enzyme changes ( a ) is in accordance with the proposal that an increased cellular level of long-chain acyl-coa species act as metabolic messages for induction of peroxisomal beta-oxidation and palmitoyl-coa hydrolase , i.e. , these enzymes are regulated by a substrate-induced mechanism , and ( b ) indicates that , with phfo , a greater part of the activated fatty acids are directed from triacylglycerol esterification and hydrolysis towards oxidation in the mitochondria .
C0007634
cellular
C0026237
mitochondria