the intragastric administration to male wistar rats of t-2 toxin at 1-1.3 mg/kg body weight for 7 days caused a sharp decrease in the liver activity of lysosomal enzymes : beta-galactosidase , beta-n-acetylglucosaminidase , alpha-mannosidase , cathepsins a , b , c and d and in the activity of enzymes of the 1st phase of metabolism of xenobiotics -- aniline hydroxylase and carboxylesterase , as well as in the cytochrome p-450 level .
C0025519
metabolism
C0010762
cytochrome p-450