when 20 ml of 50 mmol/l pure synthetic bile salts ( ph 6.5 ) , of approximately the same composition as human bile , were infused into the duodenum of six healthy volunteers over 5 min during constant gastric aspiration , plasma immunoreactive secretin increased from 2.5 +/- 0.4 pmol/l to 3.6 +/- 0.5 pmol/l at 10 min ( p < 0.025 ) .
C0005404
bile salts
C0005388
bile