in the presence of co , this reaction consumes two protons : [ formula : see text ] the consumption of these protons could not be detected by a ph electrode in the extra-cellular bulk phase of a suspension of spheroplasts unless the cytoplasmic membrane was made permeable to protons by the addition of nigericin or tetrachlorosalicylanilide .
C0007634
cellular
C0007603
cytoplasmic membrane