the ability of hyp to modulate the toxicity of antimetabolites affecting purine synthesis ( 6- diazao -5- oxonorleucine , 6-methylmercaptopurine riboside , 6-mercaptopurine , and 6-thioguanine ) was determined in vitro using human b-lymphoblast ( wi-l2 ) and promyelocytic leukemia ( hl-60 ) cell lines .
C0034140
purine
C0039902
6-thioguanine