neca was the most potent analog ( ec50 , 1 microm ) , whereas pia ( ec50 , 15 microm ) , 2-cl-ado ( ec50 , 15 microm ) and meca ( ec50 , 24 microm ) , were less potent and had efficacies relative to neca of 0.61 , 0.61 and 0.65 , respectively .
C0031484
pia
C0001443
neca