ischemic deporalization of cell membranes is associated with a precipitous influx of calcium from the extracellular to the intracellular compartment , and it is suggested that increased intracellular calcium in ischemic brain leads to an activation of phospholipase and to increase of the concentration of free fatty acids , in particular arachidonic acid , with energy depletion .
C0006104
brain
C0086045
concentration