in a companion paper we described the disposition of a 75 mg single dose of amitriptyline in normal volunteers who were phenotyped as extensive or poor metabolizers of debrisoquine and bufuralol , and had a four-fold range in the oral clearance of the antidepressant , 50 mg of amitriptyline was also administered to the same volunteers .
C0003289
antidepressant
C0002600
amitriptyline