isoprenaline ( 0.1 micrograms/kg/min/10 min ) increased both heart rate ( +98 +/- 14 % ) and contractility ( +36 +/- 5 % ) and decreased diastolic blood pressure . beta 1-adrenoceptor blockade abolished the isoprenaline induced increase in contractility whereas the induced tachycardia was reduced by approximately 50 % .
C0022245
isoprenaline
C0039231
tachycardia