in order to determine the mechanisms underlying these responses primary cultures of human articular chondrocytes were preincubated with recombinant human interleukin 1 beta or the phorbol ester , phorbol 12-myristate 13-acetate , in the presence or absence of the cyclooxygenase inhibitor , indomethacin .
C0031586
phorbol ester
C0039654
phorbol