titers of circulating interferon ( ifn ) and the activity of 2'-5 ' oligoadenylate ( 2-5a ) synthetase , an enzyme specifically induced by ifn , were measured in 28 homosexual men with acquired immunodeficiency syndrome ( aids ) who received one- to six-month courses of antineoplastic therapy with ifn-alpha and in homosexual and heterosexual controls .
C0021747
interferon
C0001175
acquired immunodeficiency syndrome