consistent with this finding , desulfated and n-resulfated heparin , which had a similar composition to the urine-derived scleroderma-inducing glycosaminoglycan , induced a significant degree of sclerotic fibrosis in the skin of mice which had received intraperitoneal injections of it , whereas n-desulfated heparin with contrasting sulfation to it failed to cause any significant change in the skin .
C0019134
heparin
C0017973
glycosaminoglycan