results obtained with thiols and iodoacetamide suggested that albumins denatured by disulphide-bond reduction and alkylation , disulphide-bond reduction without alkylation , or by treatment with 8 m-urea , were all degraded primarily by cathepsin d in lysosomes , but formaldehyde-denatured albumin was attacked by thiol proteinases .
C0007427
cathepsin d
C0024369
lysosomes