the organism appeared to cross the mucosal barrier by several mechanisms : ( a ) penetration into the cytoplasm of intact epithelial cells , ( b ) passage between epithelial cells that were separated by excessive hydrostatic pressure generated during bladder inoculation , ( c ) passage across necrotic regions of the pelvis , and ( d ) translocation to the cortex by calicotubular backflow .
C0005682
bladder
C0030797
regions