a double-blind parallel group study was carried out in patients with mild to moderate hypertension to assess the effects of 6 mg piretanide once or twice daily , in comparison to 50 mg hydrochlorothiazide plus 5 mg amiloride once daily , on serum trace-element levels over a period of three months .
C0020538
hypertension
C0020261
hydrochlorothiazide