the lower frequencies of ica in patients with iddm onset before 5 yr of age suggest that some of these patients may have a different etiology and/or a more rapid disappearance of islet cell antigens than patients with a later onset.l the lower ica frequencies in black patients can be explained by heterogeneity of iddm in this group and by admixture of iddm susceptibility genes from the caucasian genome to the black genome .
C0022131
islet cell
C0011854
iddm