these results formally demonstrate that the mechanism of action of pzq , the most important anti-schistosomal compound in current use , involves a synergy between the drug and the humoral immune response of the host , and suggest that the relevant effector antibodies act directly against parasite antigens which become exposed on the surface of the worms as a consequence of interaction with the drug .
C0020967
humoral immune response
C0003320
antigens