the most striking difference was in the relative preference for acetylation of histone h4 versus acetylation of histone h3 : with the purified acetylase , histone h4 in nucleosomes was acetylated to a much greater extent than was histone h3 , whereas the reverse preference was found with the endogenous acetylase ( s ) .
C0028623
nucleosomes
C0019647
histone h3