incomplete coincidence of histochemical changes following hypophysectomy with the changes caused by the action of cortisone for the same period ( 10 days ) , and also a distinct depression with cortisone of histochemical shifts characteristic of the action of acth in hypophysectomized animals pointed to the direct ( not mediated through the hypophysis ) influence of cortisone on the adrenal cortex .
C0020632
hypophysectomy
C0032005
hypophysis