the results show that at the intracellular level of gsh and gssg , thiol groups in reduced , unfolded ribonuclease are oxidized to form intramolecular cystine cross-bridges , while thiol groups of typical cysteine enzymes , such as lactate and malate dehydrogenase , remain in their reduced state during refolding .
C0017817
gsh
C0061516
gssg