in this experiment , the absorption , excretion , distribution and metabolism of 2,6-dimethyl-3,5-dimethoxycarbonyl-4- ( o-difluoromethoxyphenyl ) -1 , 4-dihydropyridine ( pp-1466 ) were investigated following oral or intravenous administration , single dose or repeated dose administration using male slc-wistar rats and the results of this investigation were summarized as follows : after oral administration of 14c-pp-1466 to rats , the blood level reached the maximum at 1 h and decreased with the biological half-life of about 5 h .
C0221102
excretion
C0025519
metabolism