lack of growth potential in vivo for one variant appears to reflect the inability for net intracellular accumulation of reduced folate per se , since growth of this variant could be restored by treatment of mice with folic acid , but not with 5-methyltetrahydrofolate or 5-formyltetrahydrofolate , and following reversion to a more transport-proficient phenotype .
C0016410
folic acid
C0023413
5-formyltetrahydrofolate