we have demonstrated in in vivo studies with a monoclonal anti-il-4 antibody that this cytokine is required for the generation of the polyclonal primary ige responses induced by injecting mice with gam delta antibody or inoculating them with larvae of the nematode parasite nippostrongylus brasiliensis ( nb ) , as well as for the secondary tnp-specific ige response induced by immunizing mice with tnp-klh on alum .
C0003250
monoclonal
C0003241
antibody