to explore the hypothesis that depressed patients with low pretreatment levels of urinary 3-methoxy-4-hydroxyphenylglycol ( mhpg ) respond more favorably to antidepressant drugs which act on noradrenergic neuronal systems than do patients with high mhpg levels , the authors administered 150 -- 200 mg/day of imipramine or maprotiline to 13 depressed patients .
C0003289
antidepressant drugs
C0020934
imipramine