this action of inositol 1,4,5-trisphosphate is associated with a significant formation of thromboxane b2 , activation of phospholipase c , and phosphorylation of 20,000- and 40,000-dalton proteins , which are the substrates for myosin light chain kinase and protein kinase c , respectively .
C0031715
phosphorylation
C0027120
myosin light