based on previous evidence for the existence of an initiator of coagulation together with coagulation factor intermediates associated with viable sccl tumor cells in situ , and also for the favorable effects of anticoagulant therapy with warfarin in sccl , we postulate that local tumor cell-induced thrombin formation may contribute to self-regulated progression of sccl through deposition of fibrin and stimulation of cell proliferation .
C0005789
coagulation factor
C0040018
thrombin