to determine the effect of streptokinase on the ischemic myocardium independent of its effects on the occluding thrombus , the isolated rabbit heart , perfused with krebs-henseleit solution , was subjected to a 45-min period of ischemia -- 83 % reduction in myocardial ( perfusion ) flow -- plus anoxia ( 95 % n2 and 5 % co2 ) , followed by restoration of perfusion and reoxygenation .
C0018787
heart
C0027061
myocardial