the igg anti-ige activity appeared to be directed toward the fc portion of ige because absorption of positive sera over ige ( adz ) sepharose but not over myeloma igg sepharose completely removed their reactivity with ige ( ps ) and because sera from atopic individuals but not from normal subjects contained igg anti-ige activity against the protein backbone of the fc portion of ige synthesized from a fragment of the cloned gene of human myeloma ige ( nd ) heavy chain .
C0086418
human
C1420192
heavy chain