it has been proposed that the process of ligand binding to hemoproteins is governed by sequential potential barriers as depicted in the following scheme [ austin et al. , biochemistry 14 , pp . 5355-5373 , 1975 ; ansari et al. , proc . natn . acad . sci . usa . pp . 5000-5004 , 1985 ] : ( formula ; see text ) at sufficiently high temperatures ( approximately 300 k ) , the binding process is exponential in time and its velocity proportional to the concentration of the ligand in the solvent .
C1517880
ligand binding
C1418943
proc