we report a small kindred in which the father and daughter with positive antinuclear antibodies ( ana ) ( proband ) had diffuse cutaneous and visceral scleroderma ( systemic sclerosis , ssc ) , antitopoisomerase autoantibodies and shared the hla-a23 c- b- dr5 drw52 dqw3 haplotype .
C0011644
scleroderma
C0036421
systemic sclerosis