the cardiovascular effects of 8-oh-dpat were not prevented by pretreatment with methergoline , methiothepin , pirenperone or cianserine or by 5-ht depletion by means of p-chlorophenylalanine , which suggests that the putative 5-ht receptor that is responsible for the hypotension and bradycardia to 8-oh-dpat is not of a presynaptic type and does not have the pharmacological characteristics of a general 5-ht1 receptor .
C0007226
cardiovascular
C0428977
bradycardia