it is concluded that ( 1 ) ml-236b causes a transient bile salt-independent choleresis , ( 2 ) ml-236b depresses excretion of bile salts and lipids by blocking mevalonate synthesis and not by blocking the bile salt or lipid transport , ( 3 ) biliary excretions of phospholipids and cholesterol partly depend on excretion of bile salt , and ( 4 ) in rats with a prolonged total bile diversion newly formed mevalonate is a major substrate for bile salt synthesis .
C0005388
bile
C0005404
bile salt