thus , the induction of c-fos and c-myc may be a necessary step in the mitogenic response initiated by ligands that act through activation of protein kinase c but the expression of these proto-oncogenes may not be an obligatory event in the stimulation of mitogenesis in 3t3 cells by mitogens that utilise other signalling pathways .
C1156237
mitogenesis
C0026249
mitogens