however , over a 240-hr period of observation , the elimination rate from dna of o6-ethylguanine ( a modified base likely to cause anomalous base pairing during dna replication ) was strikingly slower in brain ( half-life , about 220 hr ) as compared to liver ( about 30 hr ) , and also much slower than the elimination rates from brain dna of n7-ethylguanine ( about 90 hr ) and n3-ethyladenine ( about 16 hr ) .
C0598312
dna replication
C0012854
dna