to determine whether the reduction in cholesterol esterification was due to a direct inhibition of acat or to an effect of verapamil on the transport of cholesterol to the site of acat activity , the cells were incubated with acetylated ldl labelled with 3h-cholesteryl ester , and the amount of uptake , lysosomal hydrolysis , and cytoplasmic reesterification was determined .
C0007634
cells
C0010834
cytoplasmic