when the subjects were treated with captopril ( 25 mg t.i.d . ) for 2 to 4 weeks , supine mean arterial pressure decreased from 130 to 114 mm hg ( -12 % ; p less than 0.05 ) , heart rate did not change , supine and upright plasma renin activity increased , while supine plasma norepinephrine and epinephrine concentration decreased slightly .
C0028351
norepinephrine
C0014563
epinephrine