although phosphorylation is a prerequisite for the anti-retrovirus activity of the 2',3'-dideoxynucleoside derivatives , there is no close correlation between the anti-retrovirus potency of the 3'-fluoro- and 3'-azido-substituted ddurd , ddthd , ddeturd and ddcyd derivatives and their affinity for dthd kinase or dcyd kinase .
C0031715
phosphorylation
C0031727
kinase