acyclovir or placebo was administered to 49 patients for 5 weeks beginning 1 week before transplantation : 5 of 24 patients receiving acyclovir developed herpes simplex virus infection during prophylaxis , compared to 17 of 25 patients receiving placebo ( p less than 0.01 ) .
C0001367
acyclovir
C0019348
herpes simplex virus infection