to differentiate between extrarenal and renal causes of hyperuricaemia and gout , clearances of urate and creatinine were monitored for 3 1/2 days in fifty-two individuals ( seven with a history of gout ) with no gross impairment of renal function ( creatinine clearance 52-137 ml/min ) .
C0022646
renal
C0035078
impairment