several explanations for the phenomenon are suggested : 1 ) emiocytosis is probably more frequent in the colon than in the proximal gut , this allows its observation without requiring an exogenous stimulus , 2 ) since most of the exocytotic figures are from anaesthetized subjects it is also assumed that contraction of the muscular layer induced by anaesthetics and the resulting increase in intraluminal pressure were the possible causes of granule release , 3 ) in non-anaesthetized subjects release may have taken place in response to a normal endogenous physiological stimulus , or to the dilation of colon during colonoscopy .
C0017189
gut
C0009378
colonoscopy