this study evaluated by echocardiography ( m-mode tracings , two-dimensional-guided ) the effects of captopril administration for one year ( 25 to 50 mg twice a day , alone or in combination with hydrochlorothiazide when necessary ) on left ventricular mass index , on systolic function at rest and during stress ( hand grip for three minutes and cold pressor test for three minutes ) , and on diastolic function in 15 patients with essential hypertension ( 13 men and two women , aged 30 to 67 years ) with left ventricular hypertrophy .
C0006938
captopril
C0149721
left ventricular hypertrophy