propranolol induced a significant reduction of heart rate and cardiac output averaging 20.9 % and 20.3 % , respectively ( p in both cases < 0.0001 ) at equal exercise levels , no change in stroke volume , and a slight increase in the pathologically elevated exercise mean pulmonary artery pressure , with the pulmonary vascular resistance remaining unchanged .
C0033497
propranolol
C0428977
reduction