the quasi-similar values for the dissociation constants between fibrin and t-pa ( kd ) and between pai-1 and t-pa ( ki ) , as well as the competitive type of inhibition observed , indicate that the fibrinolytic activity of human plasma may be the result of an equilibrium distribution of t-pa between both the amount of fibrin generated and the concentration of circulating inhibitor .
C0032105
plasma
C0015982
fibrin