in most cells the fibrous substance undergoes differentiation : a ) in stratum spinosum into compact tonofibrils with no individual tonofilaments visible ( fibrous substance of spinous-cell type ) , b ) in stratum inter-medium into compact tonofibrils with intensely stained regions or keratohyalin ( fibrous substance of intermediate-cell type ) , and c ) in stratum corneum into tonofibrils with a keratin pattern ( fibrous substance of horny-cell type ) .
C0007634
cells
C0007589
differentiation