in a controlled investigation of the long-term effect of lithium on protein-bound iodine ( pbi ) , 17 manic-depressive patients were placed on lithium for 6 months then shifted on a double blind basis to lithium ( 8 patients ) and placebo ( 9 patients ) , and followed for a maximum of 3 years .
C0005586
manic-depressive
C0023870
lithium