it is concluded that the imidazole-containing agents clotrimazole and miconazole , and to a much lesser extent ketoconazole , are potent inducers of the rat hepatic microsomal mixed-function oxidases , displaying selectivity towards the p-450iib ( phenobarbital-inducible ) and p-450iii ( pcn-inducible ) families of cytochrome p-450 proteins .
C0003927
microsomal mixed-function oxidases
C0010762
cytochrome p-450