photoalkylation of circular covalently closed dna from phage pm2 with isopropyl alcohol by using a free radical photoinitiator and uv light of lambda greater than 305 nm led to the specific 8-substitution of purine moieties in the dna , yielding 8- ( 2-hydroxy-2-propyl ) adenine and 8- ( 2-hydroxy-2-propyl ) guanine as the only detectable damage in the dna .
C0012925
circular
C0012854
dna