epithelial cells incubated without arachidonic acid failed to generate detectable quantities of metabolites , while cells incubated with arachidonic acid at 1-50 micrograms/mf for 1-30 min invariably generated predominantly 15-lipoxygenase products , including 15-hydroxyicosatetraenoic acid ( 15-hete ) , four isomers of 8,15-dihydroxyicosatetraenoic acid ( two 8,15-dihetes and two 8,15-leukotrienes ) , at least one isomer of 14,15-dihydroxyicosatetraenoic acid , and smaller amounts of 12-hete and 8-hete , but little or no detectable 5-hete or 5,12-dihetes .
C0044800
12-hete
C0020349
hete