in cholesterol gallstone patients , chenodeoxycholic acid treatment reduced the mean enzyme activity by 51 % compared with the untreated gallstone group ( p < 0.001 ) and in smaller doses , ursodeoxycholic acid therapy lowered it by 40 % ( p < 0.001 ) but in the two patients with pigment stones , cdca did not seem to affect hmgcoar activity .
C0008350
gallstone
C0042105
ursodeoxycholic acid