the increase in synthesis of numatrin in normal b cells was found to be associated exclusively with cellular commitment for mitogenesis because activation of b cells by stimuli such as b cell stimulating factor 1 , pma alone , and calcium ionophore a23187 , which do not stimulate an increase in dna synthesis , also failed to induce an increase in the synthesis of numatrin .
C0007634
cellular
C1156237
mitogenesis