cytogenetic analysis in a patient with erythroleukaemia revealed a hypodiploid cellular clone with several acquired karyotypic aberrations including an isochromosome for the long arm of chromosome 21 : 45 , xy , -5 , -7 , -18 , -19 , -21 , + 17 , + i ( 21q ) ( qter leads to cen leads to qter ) , + mar1 , + mar2 .
C0007634
cellular
C1521075
21q