when nafimidone ( nfm ) , a new antiepileptic drug , was given to six patients already taking carbamazepine ( cbz ) and phenytoin ( pht ) as part of a late phase i pilot efficacy trial , it reduced cbz elimination by 76-87 % and reduced pht elimination by 38-77 % .
C0003299
antiepileptic drug
C0031507
pht