to demonstrate that microinjection into the lateral ventricle intracerebroventricular ( i.c.v . ) of the brain of monkeys does not perturb normal function of the hypothalamic-pituitary axis , ovariectomized cynomolgus monkeys were treated with a bolus of estradiol benzoate ( e2beta ) ( to hours ) and an i.c.v . injection of 100 microliters of saline solution at t-6 ( group i : four monkeys ) or at t+26 hours ( group ii : three monkeys ) .
C0152279
lateral ventricle
C0006104
brain