while all the new antiarrhythmic drugs currently studied will cause some degree of hemodyanmic depression in an appropriately high concentration , present investigations suggest that particular caution needs to be taken when disopyramide , aprindine , atenolol , and verampamil are administered either acutely by the intravenous route or chronically by the oral route .
C0003195
antiarrhythmic
C0012702
disopyramide