the exposure of normal pancreatic islets to cyclosporin-a ( 1 microgram/ml ) for 24 hr resulted in significant inhibition of glucose-induced ( 16.7 mm ) insulin release from 197 +/- 14 microu/10 islets/15 min ( control ) to 103 +/- 14 microu/10 islets/15 min ( cy-a-treated islets ; p less than 0.001 ) .
C0022131
pancreatic islets
C0021641
insulin