to date , high dose ( 2 mg/kg every 2 hours 3-5 times ) metoclopramide is considered to be the most effective drug against emesis induced by high-dose ( 100-120 mg/m2 ) cisplatin , and a combination therapy of metoclopramide , dexamethasone , diphenhydramin and lorazepam appears to be the most effective .
C0042963
emesis
C0024002
lorazepam