our initial observation that the replicative dna polymerase alpha might be the target of the action of betalactam compounds ( hubscher et al . cell biol toxicol . 2 , 541-548 , 1986 ) is now substantiated due to the following experimental data : ( i ) extractable dna polymerase alpha is greatly reduced in cells that had been treated with bla ;
C0282215
betalactam
C0026458
bla