the presence of activity of enzymes of cyclic nucleotide metabolism in the cell nucleus and the sensitivity of nuclear guanylate cyclase , capde and cgpde to carbamylcholine , which in the same concentration range enhances activity of dna and rna polymerases , suggested the hypothesis that effects on cyclic nucleotide-dependent phosphorylation of nuclear proteins might be among regulatory mechanisms by which the drug alters rates of replication and transcription in corneal epithelial cells .
C0007610
cell nucleus
C0028589
nuclear proteins