based on the assessment of morphological abnormalities in leukaemic cells and of mitotic indices in bone marrow smears , it is tentatively concluded that the acute myeloblastic leukaemia in this dog arose in the pluripotent haematopoietic stem cell compartment giving rise to the formation of erythrocytes , eosinophils , neutrophils and monocytes as well as megakaryocytes and that the proliferation rate of cells of the myeloblastic clone was decreased , although an increase in the size of the potentially dividing compartment might have occurred .
C1517806
leukaemic cells
C0023467
acute myeloblastic leukaemia