anaphylatoxins , in particular c3a and c5a , have various biological activities which suggest a role as mediators of inflammatory reactions : they cause contraction of smooth muscle , histamine release , increase in capillary permeability , adhesion of leukocytes to vascular endothelium , leukocyte chemotaxis , and aggregation of platelets and leukocytes .
C0002791
anaphylatoxins
C0009510
c3a