that enprofylline did not antagonize the r-pia-induced contractions , but was 3-4 times more potent a tracheal relaxant than aminophylline , further suggests that a direct effect on airway smooth muscle , rather than antagonism of endogenous adenosine , is more relevant to the bronchodilator effect of alkylxanthines in the treatment of asthma .
C0002575
aminophylline
C0004096
asthma