adrenocorticotropic hormone ( acth1-39 ) noncompetitively inhibited specific binding at 5-ht1 , 5-ht1a , and 5-ht2 sites in brainstem and neocortex [ concentrations required to displace 50 % of ligand binding ( ic50s ) 4-8 x 10 ( -5 ) m ] .
C1415803
5-ht1a
C1517880
ligand