the cerebrovascular resistance ( cvr ) during normocapnia in the pentobarbital group was significantly higher ( p less than 0.01 ) than in the nitrous oxide group thus indicating a vasoconstrictor effect of pentobarbital that may be clinically important , because the ability of barbiturates to contract vessels in healthy brain regions may partly explain the protective properties of these drugs against cerebral ischemia .
C0030883
pentobarbital
C0004745
barbiturates