the principal findings were ( a ) markedly increased glycosaminoglycan content in all neural tissues examined ( from threefold in sciatic nerve to 15-fold in brainstem ) , ( b ) a modest increase in levels of gangliosides gm2 , gm3 , and gd3 , particularly in gray matter , ( c ) excessive accumulation of glycosaminoglycans in the csf , ( d ) the increased glycosaminoglycans were dermatan sulfate and heparan sulfate , and ( e ) the molecular weights of the liver glycosaminoglycans were shifted toward smaller sizes , indicating partial degradation .
C0019143
heparan sulfate
C0017973
glycosaminoglycans