it was demonstrated that 1,4-bis [ ( 2-aminoethyl ) amino ] -5 , 8-dihydroxy-9,10-anthracenedione dihydrochloride ( aead , 2 ) derived from mitoxantrone ( mx , 1 ) by removing hydroxyethyl groups from both side chains was extremely active in depressing immune responses in vitro and in vivo .
C0003174
anthracenedione
C0026259
mitoxantrone