the administration of a single intravenous injection of indomethacin was followed by a major constrictive effect on the ductus in 36 of 42 very-low-birth-weight ( less than or equal to 1000 gm ) infants with symptomatic patent ductus arteriosus ( pda ) .
C0021246
indomethacin
C0013274
patent ductus arteriosus