the most frequent signs and symptoms observed by clinical examination are : fever ( 30 % ) , nodes ( 86.3 % ) , prurigo ( 43.3 % ) , splenomegaly ( 15.3 % ) , hepatomegaly ( 1 % ) , headache ( 72.6 % ) , vigilance and sleeping disturbances ( 68.7 % ) , perioral reflexes ( 67.6 % ) , cheiro-oral reflexes ( 64.3 % ) , movement disorders consisting of tremor , choreo-athetosis movements , buccal dyskinesia or seizures ( 35 % ) , motor palsy and gait disorders ( 15 % ) , tonus disturbances ( 12.3 % ) , sensitivity abnormalities ( 17 % ) , endocrine disorders ( 16.3 % ) , psychiatric symptoms ( 6.3 % ) .
C0040822
tremor
C0013384
dyskinesia