the ratio of cbz 10 , 11-epoxide ( cbz-e ) to the parent drug was significantly higher ( p less than 0.01 ) in those patients taking concomitant phenytoin ( n = 9 ) , phenobarbitone or primidone ( n = 9 ) , and valproic acid ( n = 6 ) than in the patients receiving cbz alone .
C0031412
phenobarbitone
C0033148
primidone