antibody 1083-17-1a was modified by attachment of 3- ( 2-pyridyldithio ) propionyl or cystaminyl groups and then treated with reduced a chain to give disulfide-linked conjugates that retained the original binding specificity of the antibody moiety . the conjugates showed cytotoxic activity for colorectal carcinoma cells in culture , but were not toxic in the same concentration range for a variety of cell lines that lacked the antigen .
C0812305
17-1a
C0009402
colorectal carcinoma