the indication that il 2 may be adsorbed in vivo by the neoplastic b cells was further confirmed by the demonstration of the il 2 receptor ( revealed by anti-tac monoclonal antibody ) on the leukemic b cells , particularly following mitogenic stimulation , and by the evidence that exogenous il 2 can be directly absorbed by untreated b-cll t lymphocytes to release ifn-gamma and il 2 is preserved , but that il 2 may be rapidly removed by the neoplastic b-cll cells , thus contributing to the well-documented t lymphocyte abnormalities present in this disease .
C0597032
neoplastic
C0023434
b-cll