since it was confirmed that the affinity for antithrombin iii of whale heparin is of the same nature as those of hog and bovine heparins by ( a ) fluorometric titration and ( b ) affinity chromatography on an antithrombin iii-sepharose column saturated with hog ha heparin , the above difference in anticoagulant properties between the whale ha heparin and hog and bovine ha heparins may be considered to be due to a difference in undescribed saccharide-sequence structures at sites other than the well-characterized antithrombin iii-binding sites , suggesting strongly that some heparin saccharide structures other than antithrombin iii-binding oligosaccharide participate in the anticoagulant activity dependent on antithrombin iii-heparin binding -- at least in the manifestation of anti-thrombin activity and the enhancement of anti-xa activity .
C0019134
heparin
C0019139
anti-xa