using a test system developed for the definition of interleukin 4 ( il-4 ) , which is a b cell-stimulating lymphokine which preferentially activates the synthesis of selected ig classes in mouse lymphoid cells , we have shown that ra-sf has properties similar to il-4 in that it induces differentiation of antibody secretion in the lps-pretreated mouse cell , but unlike il-4 , which gives igg1 and ige , it selectively induces igg2b synthesis .
C0007589
differentiation
C0007634
cell