this study , based on results of 252 cadaver kidney transplantations , shows that some factors which reflect individual immune response capacity , such as ability to produce anti-hla antibodies , sex and response to hepatitis b virus , appear , along with hla compatibility , to markedly influence renal graft survival and leads us to propose the following new guide-line for cadaver kidney recipient selection : for `` '' good responders '' '' ( i.e. , patients with anti-hla antibodies , females and hbs ag negative individuals ) a close hla compatibility with the donor ( 3 or 4 antigens in common ) is necessary , while this need not be observed for `` '' non-responders '' '' ( i.e. , patients without preformed anti-hla antibodies , males and hbs ag persistent carriers ) .
C0301872
immune response
C0003320
4 antige