in certain myeloid leukemic cells , such as hl-60 , interferon by itself is growth suppressive but does not induce cell maturation , whereas in combination with inducers of differentiation , such as dmso , tpa or retinoic acid , interferon potentiates their ability to stimulate differentiation in both sensitive and resistant cell populations ( grant et al. , 1982 , 1983 ; tomida et al. , 1982 ) .
C1516349
cell maturation
C0007634
cell