therefore , in addition to anti-galactocerebroside activity , which was previously found to be the major antibody responsible for the demyelinating activity induced by anti-whole cns tissue antiserum , these data suggest that antibodies to gangliosides like gm1 and gm4 might also play a role in immune-mediated demyelination , including perhaps , the human demyelinating diseases .
C0003241
antibody
C0020960
antiserum