the cardinal symptoms of this type of disease , which probably is identified with the cases described in literature as atypical chronic myelosis , as paraneutrophil leukaemia or as acute myelofibrosis , and also shows common features with the juvenile chronic myelosis , are , apart from the mature cellular differential blood picture a short life expectancy ( less than 1 year ) , an initial thrombocytopenia , a normal or increased activity of the alkaline granulocyte phosphatase , the lack of ph1-chromosome as well as the bad therapeutic reaction to busulfan .
C0023473
chronic myelosis
C0006463
busulfan