to assess the effects of endogenous somatostatin on pancreatic islet a- and b-cell function , isolated rat islets were incubated in antisomatostatin gamma-globulin to bind endogenously released somatostatin , and the insulin and glucagon secretion of these islets was compared with that of islets incubated in gamma-globulin isolated from nonimmune serum .
C0022131
pancreatic islet
C0021641
insulin