introduction of ca2+ into the cells via the ca2+ ionophore a23187 or the addition of the tumor-promor 12-o-tetradecanoylphorbol-13-acetate ( tpa ) , which is a stimulator of protein kinase c , does not induce circular ruffle formations on human fibroblasts , neither does the addition of the combination of these two agents .
C0007634
cells
C0016030
fibroblasts