after fractionation of tissue homogenates in 0.25 m sucrose by differential centrifugation , about 25 % of the total cellular gnrh degrading activity was found to be sedimentable and recovered from heavy ( m ) and light ( l ) mitochondrial fractions with a distribution pattern similar to that of the mitochondrial and lysosomal reference enzymes cytochrome oxidase and beta-galactosidase .
C0007634
cellular
C0026237
mitochondrial