we administered crf as an intravenous bolus or as a continuous infusion to normal volunteers and as an intravenous bolus to patients with disorders of the hypothalamic-pituitary-adrenal axis , such as cushing 's syndrome and adrenal insufficiency , and patients with endogenous depression and mild hypercortisolism , and assessed their plasma acth , cortisol , gh and prl responses .
C0010481
cushing 's
C0001622
hypercortisolism