under conditions of steady-state hyperglycemia ( +75 mg/100 ml hyperglycemic clamp , insulin secretion was reduced by 75 % in the streptozotocin-treated dogs ( p less than 0.025 ) , and the total amount of glucose metabolized decreased from 13.56 +/- 1.04 to 4.74 +/- 0.70 mg/min x kg ( p less than 0.001 ) .
C0020456
hyperglycemia
C0017725
glucose