exposure of c3h 10t1/2 cl 8 cells , synchronized by release from confluence-induced arest of proliferation , to different concentrations of n-methyl-n'-nitro-n-nitrosoguanidine ( mnng ) for 30 min at various points during the cell cycle causes dose-dependent toxicity ( decrease in relative colony-forming efficiency or `` '' survival '' '' ) that increases linearly during the first g1 phase , reaches a maximum in early to middle s phase , and decreases during late s .
C0007634
cells
C0080129
y