the purpose of the paper was to determine whether two clinically active antirheumatic compounds , cyclosporin-a ( cs-a ) and methotrexate ( mtx ) were efficacious in the treatment of adjuvant arthritis ( aa ) in rats , as measured by reduction of paw inflammation , lymphocyte activating factor ( laf ) activity and the acute phase response .
C0021368
inflammation
C0001349
acute phase response