since a good correlation exists in vitro among all the compounds studied in reducing action potential duration , relaxing vascular tissue , and decreasing cardiac contractility , it is concluded that pinacidil as well as nicorandil and brl 34915 affect vascular and cardiac tissues by similar mechanisms , possibly by increases in potassium ion permeability , although other mechanisms may also play a role .
C1511228
vascular tissue
C0005847
vascular