analogues of methotrexate ( mtx ) and aminopterin ( amt ) with aminophosphonoalkanoic , aminoalkanesulfonic , and aminoalkanephosphonic acid side chains in place of glutamate were synthesized and tested as inhibitors of folylpolyglutamate synthetase ( fpgs ) from mouse liver .
C0025677
methotrexate
C0002583
aminopterin