previous work is briefly reviewed and special attention is given to discussion , with examples , of the various types of particulates which may be found in tissues ( exogenous , endogenous , inhaled , injected , ingested , inorganic , organic ) , the different tissues in which they may be found ( lung , heart , liver , skin , brain , kidney , lymph nodes , etc . ) , methods of tissue sampling ( e.g . pulmonary lavage , transbronchial biopsy , open biopsy , percutaneous biopsy , autopsy ) , specimen preparation ( fixation , embedding , sectioning , choice of substrate ) , sem and edxa data collection ( backscattered electron imaging , etc . ) data interpretation ( artefacts , limitations of sem and edxa ) and other new techniques ( ion microprobe , laser raman microprobe ) .
C0006104
brain
C0459471
interpretation