to explore possible mechanisms by which complement membrane attack complexes ( mac ) that are deposited in the glomerular mesangium might be pathogenic , we stimulated rat glomerular mesangial cells grown in vitro with nascent macs formed from the purified human complement components c5b6 and normal human serum and measured production of superoxide ion ( o2- ) and hydrogen peroxide ( h2o2 ) .
C0009498
complement
C0009545
membrane attack complexes