we speculate that ( a ) the site of injection ( or of invasion ) of the central nervous system determines which neural pathways become accessible for the spread of scrapie infection , and that ( b ) the duration of the neural phase of scrapie pathogenesis is related to the complexity of the pathways between the site of invasion and the clinical target areas in which , it is suggested , scrapie must replicate for disease to develop .
C0009450
infection
C0012634
disease