the in vitro specific activities of glutamate dehydrogenase and glutamine synthetase , which represent the rates of synthesis of glutamic acid and glutamine , respectively , in the presence of enzyme-saturating concentrations of substrates and coenzymes are compared with the in vivo rates of biosynthesis of [ 15n ] glutamic acid and [ alpha , gamma-15n ] glutamine observed by nmr , and implications of the results for factors limiting the rates of their biosynthesis in ammonia- and nitrate-grown cells are discussed .
C0061472
glutamic acid
C0017797
glutamine