dl-alpha-difluoromethylornithine ( dfmo ) , a specific enzyme-activated irreversible inhibitor of ornithine decarboxylase ( odc ) was previously shown to cure mice infected with trypanosoma brucei brucei , a parasite of game and cattle in africa and trypanosoma brucei rhodesiense , a human african sleeping sickness pathogen .
C0040363
to
C0001737
africa