this antibody blocks ( in the absence of complement ) : ( 1 ) specific binding of peripheral blood lymphocytes ( pbl ) to antigen-pulsed monocyte monolayers , ( 2 ) proliferation of pbl in response to soluble antigen ( tetanus toxoid or mumps ) or cell surface class ii antigen stimulation in allogeneic or autologous mlr , ( 3 ) proliferation of cloned t4+ ( inducer ) lymphocyte cell lines to class ii antigens , ( 4 ) generation of cytotoxic lymphocytes during allogeneic mlr , and ( 5 ) recognition ( and killing ) of class ii-bearing target cells by t4+ ctl clones .
C0019630
class ii antigens
C0039215
cells