these findings , in conjunction with the results of our studies on urinary corticosteroid metabolites , which yielded identical findings , provide evidence for a decreased activity of hepatic cortisol-delta-4-hydrogenase enzyme system and increased activities ( presumably compensatorily ) of cortisol-20-reductase and 6-hydroxylase enzyme systems in patients with essential hypertension .
C0020284
hydrogenase
C0030016
reductase