for 371 persons in 17 kindreds , at risk for apkd by virtue of having an affected first degree relative , we calculated the estimated probability of clinical diagnosis of apkd to be 0.011 by age 20 , 0.041 by age 30 , 0.115 by age 40 , 0.299 by age 50 , and 0.404 by age 60 years ( expected = 0.50 ) .
C0085413
apkd
C0022680
of