in order to evaluate the separate effects of aminophylline on the neural and muscular components of the respiratory control system , assessed by electromyographic activity of the diaphragm ( emgd ) and mouth occlusion pressure ( p0.1 ) , respectively , 6 normal subjects and 14 patients with mild or moderate chronic airflow obstruction ( 8 asthmatics and 6 copd ) were studied during co2 rebreathing , before and after administration of a therapeutic dose of aminophylline 5.6 mg/kg .
C0035237
respiratory
C0024117
copd