treatment also led to breakdown of closed-circular mitochondrial dna , greatly enlarged mitochondrial profiles with few or no cristae , and a higher yield of mitochondrial protein per cell.a significant increase in the content of circular dna dimers and oligomers of mitochondria was observed after treatment of l-cells with cycloheximide and puromycin or treatment of chick fibroblasts with cycloheximide , and in hamster kidney cells transformed with polyoma virus .
C0007634
cell
C0016030
fibroblasts