in dogs with non-ischaemic normal hearts , isosorbide dinitrate ( isdn ; 1 mg kg-1 ) did not change markedly either the lad flow , myocardial ph or heart rate , whereas it decreased myocardial contractile force ( determined by a strain gauge arch ) slightly and both the systolic and diastolic blood pressure markedly .
C0018787
hearts
C0027061
myocardial