intravenous dose response curves demonstrated a similar about 5-times smaller potency of proinsulin in both experimental conditions ( half-maximal effective dose in intact rats for insulin 3.5 , for proinsulin 17.5 nm/kg body weight ; in eviscerated rats for insulin 3.6 , for proinsulin 18.5 nm/kg ) .
C0021641
insulin
C0033362
proinsulin