the genome dna of jc virus tokyo-1 strain [ jcv ( tokyo-1 ) ] , a variant oncogenic in rodents , was molecularly cloned directly from the brain of a japanese patient with progressive multifocal leukoencephalopathy and from tissue culture , and the restriction enzyme cleavage pattern and regulatory sequences were determined .
C0006104
brain
C0023524
progressive multifocal leukoencephalopathy