the ability of these isomeric 2-5as to interact with the 2-5a-dependent endonuclease was ascertained by three different criteria : ( i ) ability to prevent the protein synthesis inhibitory effects of 2-5a , ( ii ) activity as an inhibitor of translation in encephalomyocarditis rna-programmed l cell extracts , and ( iii ) ability to prevent binding of the radiolabeled probe , ppp5'a2'p5'a2'p5'a2'p5'a3 ' [ 32p ] p5'cp , to the endonuclease of l cell extracts .
C0597295
protein synthesis
C0035668
rna