to determine the role of cellular oncogenes in the process of cardiac growth and hypertrophy , we examined the expression pattern of eight cellular oncogenes during the developmental stage and pressure-overloaded hypertrophy of the rat heart by northern blot analysis . c-fos , c-myc and c-ha-ras were expressed in the heart in response to pressure overload and in a stage-specific manner , suggesting that these cellular oncogenes participate in the normal developmental process and hypertrophy of the heart .
C0018787
heart
C0018800
hypertrophy