the concept that hypoglycemic sulfonylureas stimulate ca2+ inflow and insulin release in the pancreatic b-cell by causing the gating of voltage-sensitive ca2+ channels was tested by comparing the cationic and secretory response of perifused pancreatic islets to gliclazide and/or an increase in extracellular k+ concentration .
C0038766
sulfonylureas
C0017631
gliclazide