immunization of rats with one r variant ( r9 ) tum- protected the rats grafted with the parental rms 9-4/0 cells against metastatic invasion of the lungs , but not against local tumour growth , and rats grafted with a czt-resistant tum+ cell variant s4t ( in vivo-derived ) against its hepatic and pulmonary metastases , while the local tumour progressed as usual .
C0024109
lungs
C0153676
pulmonary metastases