the development of hypertension in doca-saline treated rats was clearly retarded with the consecutive oral administration of propranolol ( 100 mg/kg/day ) and hydrochlorothiazide ( 10 mg/kg/day ) , but not with s-596 ( 20 , 50 and 100 mg/kg/day ) or pindolol ( 10 mg/kg/day ) .
C0020538
hypertension
C0033497
propranolol