treatment of cyc- s49 lymphoma cells , which are deficient in gs/ns ( the stimulatory component ) but contain functional gi/ni , with the phorbol ester , 12-o-tetradecanoylphorbol 13-acetate , a potent activator of protein kinase c , did not alter stimulation of adenylate cyclase catalytic activity by forskolin , whereas the gi/ni-mediated inhibition of the cyclase by the hormone , somatostatin , was impaired in these membranes .
C0031586
phorbol ester
C0039654
12-o-tetradecanoylphorbol