rats treated with guinea pig anti-gbm igg1 followed by bsa immune complex presented a severe systemic picture , with macroscopic hematuria ( 9/14 ) , several deaths ( 8/14 ) , slight proteinuria ( 24.6 +/- 5.2 mg/day ) , marked complement consumption ( delta = 49.4 +/- 2.4 uch50/ml ) , intravascular coagulation and severe diffuse interstitial pneumonia , obliteration of glomerular capillary walls by edema of endothelial cells , without deposition of immune complexes in kidneys or lungs .
C0206061
interstitial pneumonia
C0024109
lungs