the typical response to nonselective or selective beta-blockers without intrinsic sympathomimetic activity ( isa ) ( agents such as propranolol , timolol , atenolol and metoprolol ) is a bp reduction through a fall in ci and heart rate ( hr ) of approximately 20-25 % when subjects were at rest and exercising .
C0033497
propranolol
C0020649
bp reduction