a chimaeric recombinant plasminogen activator ( rscu-pa- k2 ) obtained by insertion of the second kringle ( k2 ) of tissue-type plasminogen activator ( t-pa ) ( amino acids 173-262 ) between residues asp130 and ser139 of single chain urokinase-type plasminogen activator ( scu-pa ) was purified from the conditioned medium of mouse myeloma cells transfected with the previously described plasmid pulb9137 ( pierard et al. , j. biol . chem . 262 , 11771-11778 , 1987 ) .
C0032144
plasminogen activator
C0032143
tissue-type plasminogen activator