one hour following intravenous pretreatment of rats with 50 mg/kg of the cytochrome p-450 suicide substrate 1-aminobenzotriazole ( abt ) , the metabolism of phenacetin to acetaminophen is inhibited completely [ b. a. mico et al. , drug metab . dispos . 15 , 274 ( 1987 ) ] .
C0010762
cytochrome p-450
C0025519
metabolism