timed-pregnant upj : tuc ( sd ) spf ( sprague-dawley ) rats were dosed with alprostadil ( prostaglandin e1 ) , either subcutaneously on days 6-15 of gestation at 0.0 , 0.5 , 1.0 , or 2.0 mg/kg/day or by iv infusion into the jugular vein ( 24 hr/day ) on days 7-15 at 0.0 , 0.5 , 1.0 , 2.0 , 4.0 , or 6.0 mg/kg/day .
C0002335
prostaglandin e1
C0032961
gestation