products derived from arachidonic acid ( aa ) via both the cyclo-oxygenase and lipoxygenase pathways play a role in inflammation : prostaglandins ( pgs ) , particularly pge2 , contribute to the formation of oedema , erythema and hyperalgesia whereas leukotriene b4 ( ltb4 ) , a product of the 5 ' lipoxygenase , may modulate the recruitment of leukocytes .
C0033554
prostaglandins
C0012472
pge2