to test the hypothesis that insulin-binding antibodies ( ibas ) appearing in the circulation before insulin treatment are markers of beta-cell damage , we studied the prevalence of ibas and both conventional ( if-icas ) -and complement ( cf-icas ) -fixing cytoplasmic islet cell antibodies in 60 newly diagnosed diabetic children with a mean age of 9.5 yr .
C0021644
insulin
C0003241
ibas