the omission of either component gives rise to inhibitions which are characterized by the activation of heme-regulated eif-2 alpha kinase and the concomitant phosphorylation of both endogenous heme-regulated eif-2 alpha kinase and endogenous eif-2 alpha , indicating that glucose-6-p is involved in the regulation of heme-regulated eif-2 alpha kinase .
C0031715
phosphorylation
C0031727
kinase