calmodulin-free tryptophan hydroxylase prepared by affinity chromatography on fluphenazine-sepharose is not activated by atp-mg2+ whereas addition of calmodulin to calmodulin-free enzyme restores the responsiveness of the hydroxylase to atp-mg2+ only in the presence of ca2+ .
C0041252
tryptophan hydroxylase
C0020364
hydroxylase