phospholipid methylase and cyclic nucleotide phosphodiesterase activities were studied in human b lymphoid hemopathies ( 51 patients : acute lymphoblastic leukemia , b lymphoma , chronic lymphocytic leukemia , hairy cell leukemia ) and compared with activities in lymphoblastid and burkitt lymphoma cell lines and with normal b lymphocytes : methylase activity proved to be lower in all and high grade lymphoma and inversely related to the percent of cells in s phase state ;
C0023443
hairy cell leukemia
C0004561
b lymphocytes