twenty-three cases of human hepatocellular carcinoma were examined electron microscopically , and intracytoplasmic deposits were detected and classified as follow : ( 1 ) inclusion bodies such as mallory bodies , ( 2 ) fat droplets , ( 3 ) secondary lysosomal changes such as alpha- or beta-glycogen particle accumulations surrounded by a single membrane layer , myelin figure and lipofuscin granules , ( 4 ) abnormal changes in organellae such as alpha- or beta-glycogen particle accumulations , the hyperplasia of smooth endoplasmic reticulum , finger prints , glycogen bodies , larger peroxisomes and hypertrophy of bile canaliculus-like structures , ( 5 ) degenerative changes in cytoplasm evidenced by debris , focal cytoplasmic degradation and autophagic vacuoles .
C0230789
smooth endoplasmic
C0010834
cytoplasmic