when the phorbol ester , 4 beta-phorbol-12-myristate-13-acetate ( pma ) or bacterial phospholipase c ( pl-c ) is added to a preparation of purified adult rat leydig cells , containing 2 mm cacl2 , a time- and dose-dependent decreases of lh-stimulated testosterone production is observed .
C0031586
phorbol ester
C0039654
pma