we have looked at the role played by alpha 1 and alpha 2 adrenoceptors in the control of blood pressure in the anaesthetised spontaneously hypertensive rat ( shr ) by examining the blood-pressure-lowering effects of the alpha 1-adrenoceptor antagonist prazosin and the alpha 2-adrenoceptor antagonist rauwolscine in 5 groups of animals : unoperated , adrenal demedullated , shamoperated , sympathectomised with 6-hydroxydopamine , and vehicle treated .
C0020649
blood-pressure-lowering
C0032912
prazosin