in the light of these results and concepts of the capacity of undifferentiated tumour cells for specific differentiation , the decisive importance in histogenesis ( cytogenesis ) of the renal carcinoma belongs not to the site of its origin in one or another nephron segment but to the level of differentiation of stem cells ( polypotent or monopotent ) undergoing malignization and to the direction of their further differentiation .
C0178679
histogenesis
C0007589
differentiation