one-hundred thirty eligible patients with advanced colorectal carcinoma who had received no prior chemotherapy were randomized to either methyl-ccnu , 70 mg/m2 orally every 6 weeks on day 1 , mitomycin c , 10 mg/m2 intravenously every 6 weeks on day 1 , and 5-fluorouracil ( 5-fu ) , 400 mg/m2 intravenously weekly -- ( mmf ) -- or 5-fu , 600 mg/m2 intravenously weekly ( 5-fu ) .
C0083765
mmf
C0016360
5-fu