it was found that the inhibition of thymidylate synthase in sarcoma-180 tumor tissue after single oral administration of 5-fu ( 20 mg/kg ) , ft-207 ( 30 or 120 mg/kg ) or uft ( 30 mg/kg ) were about 45 % , 20 % , 50 % or 65 % , respectively , but the activities of other enzymes involved in dna synthesis were not almost inhibited .
C0040085
thymidylate
C0598312
dna