to test the hypothesis that prostaglandins mediate early hyperfiltration and contribute to the progression of diabetic nephropathy , we examined the effects of long-term aspirin ( asa ) treatment on whole kidney gfr and renal prostaglandin e2 ( pge2 ) synthesis in control and diabetic rats 8 days and 16 weeks after streptozocin administration .
C0011881
diabetic nephropathy
C0022646
renal