in neostriatal slices prepared from the mouse , a species susceptible to the dopaminergic neurotoxicity of mptp , incubation with either mpp+ or mptp caused metabolic changes consistent with inhibition of mitochondrial oxidation , i.e. , an increase in the formation of lactate and accumulation of the amino acids glutamate and alanine with concomitant decreases in glutamine and aspartate levels .
C0002520
amino acids
C0001898
alanine