its hypertrophy in response to t.s.h . could account for certain unexplained features of myxoedema in which serum-t.s.h . is raised , such as swelling of the supraclavicular fat pad and the less commonly encountered symptoms of ascites or pericardial and pleural serous effusions which can persist for years in undiagnosed cases and respond rapidly to thyroxine when serum-t.s.h . returns to normal .
C0027145
myxoedema
C0040165
thyroxine