when isolated nuclei were incubated with [ methyl-3h ] dna substrate and subsequently fractionated into histone and non-histone protein fractions , over 90 % of the radioactivity was coeluted on a bio-rex 70 column with the non-histone fraction and only a negligible amount of radioactivity was found to be associated with the histone fraction .
C0007610
nuclei
C0019652
histone