an experimental study in rabbits demonstrated that the animals treated with vitamins a and e ( 400 iu/kg and 0.4 mg/kg , respectively ) in the presence of experimental myocardial infarction induced through ligation of the anterior descending coronary artery , showed a much more pronounced reduction of cardiac contractility as compared to the untreated animals with induced infarction or those treated with much higher doses ( 10000 iu/kg and 10 mg/kg , respectively ) .
C0027051
myocardial infarction
C0021308
infarction