noting recent evidence that pwm-stimulated normal blood mncs secrete significant amounts of polyclonal free l chain , the argument is advanced that normal blood and bone marrow contain b cells of cll-b phenotype and that secreted free l-chain-bearing clonal idiotypic markers interact with autologous cells of the idiotypic regulatory network and possess a key role in the regulation of clonal growth and ig synthesis .
C1321301
blood mncs
C0007634
cells