the action is mediated by prostaglandins , such as evidenced by : ( 1 ) abolition of the effect of bradykinin by aspirin , ( 2 ) prevention of the shwartzman reaction by infusions of pga2 and pge1 , and ( 3 ) sensitization of the normal male rat to the generalized shwartzman reaction by infusions of pga2 and pge1 , and ( 3 ) sensitization of the normal male rat to the generalized shwartzman reaction by indomethacin .
C0033554
prostaglandins
C0002335
pge1