dopamine infusion alone , in doses ranging from 0.25 to 8 micrograms min-1 kg-1 , resulted in a dose-dependent increase in effective renal plasma flow ( erpf ) and glomerular filtration rate ( gfr ) with a fall in filtration fraction ( ff ) in eight hydrated healthy volunteers and , to a lesser degree , in 12 patients with renal disease .
C0013030
dopamine
C0022658
renal disease