a split dose of all-trans retinoic acid ( ra ) totalling 5.0 mg/kg administered on gestation day 9/15 and 9/18 ( days/h ) significantly reduced the frequencies of ntd and of mutant genotypes in marked spd embryos examined on day 16 without significantly increasing the resorption frequency .
C0040845
trans retinoic acid
C0032961
gestation