previous studies having shown that chloroquine and hydroxychloroquine could reduce interleukin 1 ( il-1 ) -induced cartilage degradation in-vitro , the effects of a range of antimalarial drugs on the cartilage proteoglycan degrading actions of porcine leucocyte ( pi 4.8 ) alpha-interleukin 1 ( syn . catabolin ) have been examined using the standard bovine nasal cartilage culture system .
C0008269
chloroquine
C0020336
hydroxychloroquine