these results demonstrate that the total anp concentration in the atrium of the human heart is increased in severe chf and that the increase of anp in the human failing heart is mainly due to the increase of small molecular weight forms of anp , beta-hanp , and alpha-hanp , especially beta-hanp , and indicate that the processing of anp precursor , or gamma-hanp , in the human failing heart differs from that in the normal heart , suggesting that the failing heart augments synthesis and secretion of anp as one of its own compensatory responses .
C0018787
heart
C0018792
anp