in order to elucidate whether the alpha-adrenoceptor blockade by adimolol may contribute to the blood pressure lowering action of the compound , we tested 1 ) the effect on heart rate and blood pressure in conscious spontaneously hypertensive rats after oral administration and 2 ) the influence on the pressor effect of intra-arterially injected noradrenaline in autoperfused rat hindquarters after i.v . administration .
C0020649
blood pressure
C0028351
noradrenaline