secreted insulin is the end result of a series of steps along the biosynthetic protein-secretion pathway , including insulin gene transcription , processing of transcripts to preproinsulin mrna , translation of mrna , segregation and processing of newly made proinsulin in secretory vesicles , proinsulin to insulin conversion , transport of vesicles to the plasma membrane , and exocytosis .
C0021641
insulin
C1337112
insulin gene