in each of the synthase-negative segregants induced by thymidylate stress , a dna segment including almost the whole coding region of the transferred human thymidylate synthase gene was deleted in a very specific manner , as shown by southern blot analysis with a human alu sequence and a human thymidylate synthase cdna as probes .
C1366824
thymidylate
C0040085
thymidylate synthase