a non-complement binding monoclonal antibody that immunoprecipitates a 115/107 kd sialo-glycoprotein ( sgp-115/107 ) from glomerular cell membrane preparations and a 107 kd component from proximal tubules , intestinal cells and liver cells , induces glomerular epithelial cell alterations consisting of focal obliteration of foot process architecture , vacuolar changes in the cytoplasm , microvillous transformation of the cell surface , and focal retraction of podocytes , resulting in detachment of the epithelium from the underlying basement membrane .
C0014597
epithelial cell
C0014609
epithelium