since the activity of alcohol dehydrogenase in liver is a rate-limiting factor for ethanol metabolism in experimental animals , it is likely that the type and content of the polymorphic isoenzyme subunit encoded at adh2 , beta-subunit , and at adh3 , the gamma-subunit , are contributing factors to the genetic variability in ethanol elimination rate .
C0678701
ethanol metabolism
C1412237
adh3