the 281-2 monoclonal antibody is directed against the core protein of the cell surface hspg , as demonstrated by ( a ) recognition of the isolated proteoglycan but not its glycosaminoglycan chains , ( b ) co-localization of 281-2-specific antigen and radioactive cell surface hspg on gradient polyacrylamide gel electrophoresis and on isopycnic centrifugation , and ( c ) abolition of immunofluorescent staining of the nmumg cell surface by the intact , but not the protease-digested ectodomain of the cell surface hspg .
C0174307
core
C0062503
hspg