we investigated the immediate effect of corticosteroids on pulmonary function ( fev1 and forced expiratory flow measured between 25 % and 75 % of vital capacity ) and methacholine airway reactivity during a period of 8 hours after an intravenous bolus of 6-methyl-prednisolone ( 1 mg/kg ) or saline placebo administered in a double-blind , crossover schedule in 12 patients with well-controlled asthma .
C0025815
methyl-prednisolone
C0004096
asthma