b15-trf , which possesses both growth and differentiation activity , causes an increase in size of cl-3 cells and renders cl-3 cells responsive to il 2 , including an increased expression of il 2r ( eight-fold to 10-fold ) and the differentiation of cl-3 cells into ig secretion ( 60 to 80 % of cultured cells ) .
C0007634
cells
C0007589
the differentiation