serum from an individual with the crest syndrome ( calcinosis , raynaud 's phenomenon , esophageal dismotility , sclerodactyly , telangiectasia ) reacts not only with kinetochores , but also with a cytoplasmic , phosphorylatable polypeptide , which is shown by immunofluorescence in whole cells and immunoelectronmicroscopy in sections to be associated with actin stress fibres in cultured mammalian cells .
C0206138
crest syndrome
C0006663
calcinosis