when the intermediate filament proteins vimentin and desmin were reacted for a short period of time with the arginine-specific reagent 1,2-cyclohexanedione , the modification had a severe , inhibitory effect on the assembly of intermediate filaments and on the susceptibility of the basic , amino-terminal polypeptide of both proteins to degradation by the intermediate filament-specific , ca2+-activated proteinase .
C0042666
vimentin
C0021770
intermediate filament