the deficiency of fsh production can not be attributed to an alteration of the gonadal feed-back systems , since ( 1 ) in thyroidectomized rats , estradiol and testosterone were lower than in the controls , ( 2 ) signs of tubular atrophy were found in the testes and hence it could be expected that inhibin is low , and ( 3 ) in the absence of gonadal factors ( induced by orchidectomy ) thyroidectomized rats also showed a decrease of pituitary fsh .
C0018067
gonadal
C0029189
orchidectomy