the following results were obtained : 1 ) the increase in ach release induced by 4-ap ( 3 mg/kg i.p . ) was strongly potentiated by pretreatment with -methyl-p-tyrosine ( alpha-mpt ) which inhibits catecholamine biosynthesis or by n- ( 2-chloroethyl ) -n-ethyl-bromobenzylamine ( dsp4 ) bringing about a selective degeneration of noradrenergic fibres .
C0886584
methyl
C0051427
alpha-mpt