analysis of the recognition of hla-a2 by using target cells transfected with mutated hla-a2 encoding genes revealed that the nature of the amino acid at position 152 of the molecule is critical for recognition of the tcr-alpha beta+ as well as the tcr-gamma delta+ ctl clones since replacement of val for ala at that position resulted in abrogation of recognition of one tcr-gamma delta+ and one tcr-alpha beta+ clone and substitution of val for glu affected recognition of all clones .
C0002520
amino acid
C0061472
glu