we evaluated the ability of the antitumor agent 4- ( 9-acridinylamino ) -methanesulfon-m-anisidide ( amsacrine or m-amsa ) and its congener , o-amsa , to induce specific-locus mutations at the heterozygous thymidine kinase ( tk ) locus of l5178y/tk+/- -3.7.2c mouse lymphoma cells .
C1708726
locus
C0007634
cells