the response to lithium prophylaxis was assessed in a sample of bipolar patients subdivided into the following groups on the basis of the previous pattern of course of their illness : mdi ( sequence mania-depression-free interval ) , dmi ( sequence depression-mania-free interval ) , cc-lc ( continuous circular course with long cycles ) , cc-rc ( continuous circular course with rapid cycles ) , irr ( irregular course ) .
C0023870
lithium
C0005586
mania-depression