the antilipolytic effects and the cyclic-amp-lowering effects of the polyamines were almost completely prevented in the presence of different phosphodiesterase ( pde ) inhibitors ( 3-isobutyl-1-methylxanthine and ro 20-1724 ) and , in addition , polyamines had no effect on lipolysis stimulated by dibutyryl cyclic amp , indicating that polyamines may inhibit lipolysis by activating the pde enzyme .
C0001455
cyclic-amp
C0012054
dibutyryl cyclic amp