although osteoarthritis ( oa ) generally is considered a disorder of mechanical origin , the common occurrence of chronic mononuclear cell infiltrates in the synovium in conjunction with immunofluorescent evidence for immune-reactant products in cartilage of surgical case specimens ( knees , hips , and peripheral joints ) has suggested the local involvement of immune processes in the arthritis .
C0029408
osteoarthritis
C0022417
joints