the sensitivity of the isb is demonstrated for two different alkyldeoxynucleosides , o6-ethyldeoxyguanosine ( o6-etdguo ) and o4-ethyldeoxythymidine ( o4-etdthd ) , both of which are produced in cellular dna exposed to the alkylating n-nitroso carcinogen n-ethyl-n-nitrosourea and both of which represent dna lesions miscoding during dna replication and transcription .
C0012854
dna
C0598312
dna replication