the center ( zone 1 ) of the small tissue areas was characterized by ( 1 ) exoserosis with spongiotic dilatation of the intercellular space in the non-cornified epidermis , ( 2 ) derangement of keratinocytes with respect to shape , orientation , and number of desmosomes and fibrils , ( 3 ) dyskeratotic keratinocytes of two types , a and b , ( 4 ) agranulosis restricted to the dyskeratotic deratinocytes of type a , ( 5 ) exocytosis of mononuclear cells and langerhans ' cells into the entire non-cornified epidermis , ( 6 ) large gaps in the basement membrane between the dermis and epidermis .
C0023005
langerhans
C0014520
epidermis