we have demonstrated that dietary zinc deficiency increased the cytochrome p-450-dependent microsomal metabolism of methylbenzylnitrosamine and dimethylnitrosamine , two members of this class of dialkylnitrosamine carcinogens , while the addition of zinc in vitro noncompetitively inhibits the microsomal metabolism of these carcinogens .
C0010762
cytochrome p-450
C0025519
metabolism