to determine whether alterations in serum thyroid hormone levels affect hypothalamic-pituitary-adrenal function , we measured the plasma immunoreactive ( ir ) acth and ir-cortisol responses to 1 microgram/kg bw ovine crh ( ocrh ) given iv in the late afternoon and the plasma ir-acth , ir-cortisol , and ir-11-deoxycortisol responses to 2 g metyrapone given orally at midnight in 10 athyreotic patients during t4 treatment and 1 month after stopping t4 when they were biochemically , but not clinically , hypothyroid .
C0229671
serum
C0032105
plasma