also , the fact that estrogens and antiestrogens that form covalent bonds with the estrogen receptor modulate activity of the native ps2 gene and the ps2-tk-cat fusion gene in a manner similar to that of their reversibly binding counterparts suggests that it may be possible to use these irreversibly binding ligands to follow the interaction of hormone-receptor complexes with regions regulating estrogenic stimulation of the ps2 gene .
C0034804
estrogen receptor
C0019929
hormone-receptor