addition of the opioid antagonist naloxone in vitro resulted in a 220 % increase in the release of lh-rh by hypothalami exposed to morphine for 48 h in vivo , whereas it caused a 50 % reduction in lh-rh release from tissues exposed to morphine for 96 h in vivo .
C0020663
hypothalami
C0023610
lh-rh