the precise neuronal localization of d1 receptors in the substantia nigra has been studied autoradiographically in the rat by measuring the alterations of [ 3h ] sch 23390 binding site densities in this brain area after 6-hydroxydopamine ( 6-ohda ) induced destruction of nigrostriatal dopaminergic neurons and after ibotenate-induced lesion of striatal afferents .
C0038590
substantia nigra
C0006104
brain