the function of a transcription termination factor , rho , has been studied by using several synthetic dnas with simple repetitive base sequences as templates for transcription . rho actually exhibits various effects on transcription depending on the base sequence of the template : ( 1 ) rho terminates poly ( a ) synthesis with poly ( da ) x poly ( dt ) , poly ( dt ) , or oligo ( dt ) , leading to release of rna from rna polymerase . rho also inhibits the synthesis of other homoribopolymers such as poly ( u ) directed by poly ( da ) x poly ( dt ) and poly ( c ) and poly ( i ) directed by poly ( dg ) x poly ( dc ) , presumably by a similar mechanism .
C0040649
transcription
C0035681
rna polymerase