fusion of splenic lymphocytes from lewis rats , immunized with affinity-purified estrogen receptor from the cytosol of mcf-7 human breast cancer cells , with two different mouse myeloma lines , has provided 13 monoclonal hybridoma lines secreting antiestrophilin antibodies , each of which ( with one possible exception ) recognizes a different antigenic determinant in the human receptor molecule .
C0007634
cells
C1327616
secreting