systemic administration of the h1-receptor antagonists mepyramine ( 0.5-2 mg/kg ) , chlorpheniramine ( 1-4 mg/kg ) and promethazine ( 1-4 mg/kg ) , inhibited dose-dependently the ha-induced hyperglycemia , whereas an h2-receptor antagonist , cimetidine ( 80 nmol i.c.v . ) , was without effect .
C2757048
h1-receptor
C0033405
promethazine