after reduction of a disulfide bond at or near the mu opioid binding site in rat brain membranes , incubating membranes with 14 beta-bromoacetamido derivatives of either morphine , dihydromorphine , morphinone , or dihydromorphinone resulted in the irreversible inhibition of mu opioid binding to rat brain membranes .
C0026553
derivatives
C0012306
dihydromorphinone