to determine whether the vasodilatory action of amlodipine is due to inhibition of voltage-dependent ca2+ influx through the calcium channel , its effects on kcl-induced contraction of pig coronary artery rings and its interaction with the 1,4-dihydropyridine binding site in isolated sarcolemmal membranes were studied .
C0051696
amlodipine
C0012315
dihydropyridine