thus , in that model of non-insulin-dependent diabetes , 1 ) oral vanadate exerts a corrective insulin-like effect on impaired insulin action both at the level of liver and peripheral tissues , 2 ) impaired insulin action with no alteration of the insulin receptor tyrosine kinase is observed in the liver of untreated rats , and 3 ) corrective effect of vanadate on liver glucose metabolism is probably distal to the insulin receptor kinase activity .
C0011860
non-insulin-dependent diabetes
C0021641
insulin