in ten patients whose hypertension was not controlled by a treatment including clonidine ( 300 -- 450 microgram/day ) , the progressive addition of prazosin to a maximal dose of 4 -- 22.5 mg/day led to control of hypertension in nine cases ( mean supine blood pressure decreased from 174 -- 102 to 144 -- 88 mmhg ) .
C0032912
prazosin
C0020538
hypertension