the hypothesis has been based on the findings that ( 1 ) hormones regulate cell division in normal cells , ( 2 ) successful neoplastic transformation requires hormonal stimulation of cells receiving carcinogenic insult , ( 3 ) normal cells have finite divisional capabilities , whereas neoplastic cells possess infinite divisional capabilities , and ( 4 ) normal cells , when present in high ratio , inhibit the growth of neoplastic cells .
C0007590
division
C0007634
normal cells