the current study was designed to explore the effects of peripherally administered alpha-adrenoceptor inhibiting drugs ( either prazosin or yohimbine ) in spontaneously hypertensive ( shr ) and doca-salt hypertensive rats before the development of established hypertension , as well as to characterize changes induced by prazosin and/or yohimbine in the cardiac noradrenaline ( na ) content that might be responsible for the development of hypertension in these strains .
C0032912
prazosin
C0020538
hypertension