we have found that in liquid cultures of spleen cells of adult syrian hamsters of the f1d strain , the hematopoietic microenvironment is adequate to sustain proliferation of splenic stem cells for periods of greater than 4 mo , and permits granulocytic , monocytic , and megakaryocytic differentiation without secondary repopulation or addition of exogenous growth factors to the basic medium of rpmi 1640 plus 20 % horse serum .
C0018957
hematopoietic
C0037993
splenic