after subcellular fractionation , biopterins ( expressed as crithidia activity ) are located mainly in the soluble fraction of liver ( 61.3 +/- 6.7 ) and kidney ( 89.1 +/- 14.0 ) , whereas subcellular fractions of brain show additional higher percentage distribution in lysosomal ( 23.4 +/- 3.3 ) and microsomal ( 24.9 +/- 5.2 ) fractions due to their synaptosomal content as shown by density gradient centrifugation ( values in brackets : percentage +/- sd ) .
C0006104
brain
C0423896
content