the neuropathological study revealed systemic atrophy as type pick-disease i.e. , lobal atrophy in the frontal and the parieto-occipital regions , degenerative changes in the basal ganglia and in the thalamus , nerve cell loss in the substantia nigra and myelin pallor in the pyramidal tract .
C0004781
basal ganglia
C0038590
substantia nigra