16 courses of an 8-drug regimen including daunomycin , vincristine , cytosinearabinoside , thioguanine , methotrexate , cyclophosphamide , prednisolone and hydroxyurea , and 12 courses of a 7-drug regimen including the same drugs minus hydroxyurea were administered in 16 otherwise therapy-resistant cases of acute myeloid leukaemia .
C0010583
cyclophosphamide
C0023467
acute myeloid leukaemia