the sequential phosphorylation of hmm by myosin light chain kinase and protein kinase c results in a decrease in actin-activated mgatpase activity due to a 7-fold increase of the km for actin over that observed with phosphorylated hmm by myosin light chain kinase but has little effect on the maximum rate of the actin-activated mgatpase activity .
C0031715
phosphorylation
C0027120
myosin light