experiments were carried out in wistar rats to determine whether the loss of sensitivity of the tubuloglomerular feedback mechanism ( tgf ) which is known to occur in volume expansion is due to a change in the functional characteristics of the juxtaglomerular apparatus or to a change in some property of the tubular fluid which influences the feedback signal at the macula densa .
C0022445
juxtaglomerular apparatus
C0227662
macula densa