the method is particularly advantageous when comparing the metabolism and/or pharmacokinetics of analogues , such as doxorubicin [ ( 8s , 10s ) -10- [ ( 3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl ) - oxy ] -8-glycolyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-meth- oxy-5,12-naphthacenedione ] ( 1 ) and 4'-epidoxorubicin ( 2 ) , since both drugs and their metabolites can be analyzed under identical conditions .
C0013089
doxorubicin
C0014582
4