of significance was that subjects with hla haplotypes dr 3 , dr 4 , or both had 41.1 % lt responders at 42 days after vaccination , compared with subjects with hla-dr x/x ( lacking 3 or 4 ) who had 22.6 % responders ( p less than 0.03 ) , when influenza a/chile was used as an antigen .
C0024262
lt
C0003320
antigen