treatment-related effects observed in the mid and high dose groups consisted of ( 1 ) increased liver weights and/or liver/body weight ratios in both sexes at the interim and 13 week termination , ( 2 ) increased kidney weights and/or kidney/body weight ratios in both sexes at the terminal necropsy , ( 3 ) histopathologic evidence of hydrocarbon nephropathy in males , and ( 4 ) a slight decrease in serum glucose levels in male rats at both the interim and terminal necropsies .
C0022646
kidney
C0022658
nephropathy