mean arterial pressure ( as a percentage of control +/- sem ) during randomized infusions of 0.03 , 0.1 , 0.3 , or 1.0 microgram/kg/min was 99 +/- 1 , 95 +/- 1 ( p less than 0.05 ) , 93 +/- 1 ( p less than 0.01 ) , or 79 +/- 6 % ( p less than 0.001 ) , respectively , but no tachycardia and no augmentation of the norepinephrine release rate ( up to 0.3 microgram/kg/min ) were observed , which is in contrast to comparable hypotension induced by hydralazine or nitroglycerin .
C0028351
norepinephrine
C0020649
hypotension