octoxynol-9 , a nonionic surfactant used as a spermicidal agent in ortho-gynol ( registered trademark ) contraceptive jelly ( ortho pharmaceutical corporation , raritan , nj ) , was administered intravaginally to pregnant sprague dawley cobs cd rats at dosages of 0.5 mg/kg/day and 5 mg/kg/day ( two-thirds and six times the clinical dosage ) on days 6-15 of gestation in order to assess its teratogenic potential .
C0133689
octoxynol-9
C0032961
gestation