because betel quid chewing has been linked to the development of oral cancer , pathobiological effects of an aqueous areca nut extract , four areca nut alkaloids ( arecoline , guvacoline , guvacine , and arecaidine ) , and four nitrosated derivatives [ n-nitrosoguvacoline , n-nitrosoguvacine , 3- ( n-nitrosomethylamino ) propionaldehyde and 3- ( n-nitrosomethylamino ) propionitrile ] have been investigated using cultured human buccal epithelial cells .
C0002062
alkaloids
C0003753
arecoline