because contractile glomerular mesangial cells synthesize a pdgf-like molecule and may respond to pdgf released by infiltrating cells at the site of glomerular inflammation , we studied the effects of exogenous , highly purified pdgf on 1 ) contraction of cultured rat mesangial cells and 2 ) membrane phosphoinositide turnover and cytosolic free calcium ( [ ca2+ ] i ) , as putative mechanisms of membrane signal transduction .
C0007634
cells
C1383501
cytosolic