a substantial increase in mitotic activity , as observed in regenerating rat liver , appears not to result in a general demethylation of the 5.8s rrna but , in contrast , when rapidly dividing cells such as muscle myoblasts differentiate in vitro into postmitotic multinucleated muscle fibers , the existing 5.8s rna population is subject to a significantly increased level of 2'-o-methylation .
C0026845
muscle
C0596995
myoblasts