our results using recombinant human interleukin-2 ( il-2 ) and recombinant human tumor necrosis factor ( tnf ) against established methylcholanthrene-induced fibrosarcoma ( mca sarcoma ) pulmonary metastases showed that tnf and il-2 therapy at low nontoxic dosages alone did not produce significant tumor regression , but when combined at the same dosage synergize producing significant antitumor effects in mice induced with mca sarcoma .
C0016057
fibrosarcoma
C1261473
sarcoma