to determine if the enhanced glycemic response to epinephrine in patients with insulin-dependent diabetes mellitus ( iddm ) is the result of increased adrenergic sensitivity per se , increased glucagon secretion , decreased insulin secretion , or a combination of these , plasma epinephrine concentration-response curves were determined in insulin-infused ( initially euglycemic ) patients with iddm and nondiabetic subjects on two occasions : once when insulin and glucagon were free to change ( control study ) , and again when insulin and glucagon were held constant ( islet clamp study ) .
C0011854
iddm
C0021641
insulin