the fine structure of alpha l929 fibroblasts cultured in colchicine or vinblastine sulfate for periods as long as 48 hr was compared to control cells not exposed to antitubulins . in response to prolonged antitubulin culture , several changes in cell ultrastructure were noted : control fibroblasts contain cytoplasmic annulate lamellae ( al ) , but prolonged exposure to either vinblastine sulfate or colchicine results in enhanced development of al .
C0007634
cells
C0010834
cytoplasmic