2 ) at dna concentrations above 2.5 micrograms/ml , increased spermine stimulation is observed which appears to be due to its direct interaction with the activated dna template resulting in either selective limitation of the formation of `` '' dead-end '' '' enzyme-dna complexes or its ability to convert such nonproductive enzyme binding sites into productive sites for the initiation of synthetic activity .
C0012854
dna
C0598312
formation