a loading dose of tmp-smx ( bases on tmp ) of 10 to 12 mg/kg and a maintenance dose of 6 mg/kg every 8 h or 8 mg/kg every 12 h ( with a 2-h infusion ) should yield steady-state peak concentrations of at least 5 micrograms of tmp per ml of serum and 160 micrograms of smx per ml of serum .
C0041044
tmp-smx
C0041041
tmp