to investigate the immunomodulating properties of cis-diamminedichloroplatinum ( ii ) ( cddp ) , we studied the drug 's effects on natural killer ( nk ) lymphocyte cytotoxicity . i.p . injections of cddp ( 2-6 mg/kg ) into adult mice significantly enhanced cytolysis of yac-1 and k562 targets mediated by peritoneal and spleen cells .
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cytolysis
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cells