using a computer-assisted , least-squares , curve-fitting program , ligand , we found that the most satisfactory model for salicylate binding to 1:10 diluted normal plasma was a binding number ( n ) of 2 mol of salicylate per mole of albumin with an association constant ( k ) of 2.85 x 10 ( 4 ) l/mol , an additional binding of 0.5 mol to other sites on albumin or to other proteins , and nonspecific binding of 21 % .
C0001924
albumin
C0033684
proteins