administration to intact male rats of folic acid ( 25 mg/kg intragastrically for 14 days ) was shown to increase and that of methotrexate ( 0.5 mg/kg subcutaneously ) for 14 days ) to decrease the activities of the rat liver uridine-diphosphate-glucuronosyl- and glutathione-s-transferases .
C0016410
folic acid
C0025677
methotrexate