the following conclusions were reached.1 ) in confirmation of other studies , the abnormal vacuoles within the duodenal absorptive cells of these individuals were lipophilic.2 ) on chemical analysis there was significantly more mucosal lipid than found in normal fasting specimens , and almost the entire increase was due to triglyceride.3 ) this excess mucosal lipid was reduced by a low fat diet , but even after 34 days on such a diet there was still an excess of lipophilic material near the villus tip and increased quantities of total lipid and triglyceride when compared with material from normal subjects similarly treated.4 ) although there are demonstrable qualitative changes in mucosal and plasma lipids after an acute fat load , they are not quantitatively as great as in normal individuals .
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vacuoles