the functional role of extrajunctional alpha-adrenoceptors may be more important in disease states such as hypertension and congestive heart failure where circulating levels of catecholamines may be high and contribute to the maintenance of elevated vascular resistance . alpha 2-adrenoceptors are also associated with the intima and may play a role in the release of an endogenous relaxing factor from the endothelium .
C0034784
alpha-adrenoceptors
C0001639
alpha