the inhibitory effect of a single subcutaneous ( s.c. ) dose of three different bisphosphonates ( bps ) -- 4-amino-1-hydroxybutylidene-1,1-bisphosphonate ( ahbubp ) , 2- ( 2-pyridinyl ) -ethylidene-1,1-bisphosphonate ( 2-pebp ) , and dichloromethylene-bisphosphonate ( cl2mbp ) -- was studied in a model of retinoid-induced bone resorption , which consists of assessing the hypercalcemic effect of the arotinoid ro 13-6298 given s.c. for three days in thyroparathyroidectomized ( tptx ) rats .
C0012544
bisphosphonates
C0012081
dichloromethylene-bisphosphonate