this disparity was associated with the necessity for urinary excretion of substantial quantities of poorly reabsorbed anions ( penicillin , ketones , or diatrizoate ) , a rapidly falling serum bicarbonate level ( due to resolving metabolic or developing respiratory alkalosis ) , or substantial renal insufficiency ( serum creatinine greater than 3 mg/dl ) .
C0012004
diatrizoate
C0035078
renal insufficiency