incubation of primary cultures of hamster embryo cells ( hec ) or mouse fibroblasts ( c3h/10t1/2 cells ) in media depleted of thyroid hormones does not alter cell growth or survival but renders the cells resistant to neoplastic transformation by benzo [ a ] pyrene ( b [ a ] p ) or n-methyl-n'-nitro-n-nitrosoguanidine ( mnng ) , carcinogens which yield transformation rates of 10 ( -4 ) -10 ( -2 ) in media supplemented with triiodothyronine ( t3 ) .
C0007595
cell growth
C0007634
cells