these studies demonstrate impairment of immunoglobulin synthesis by cultured lymphocytes from untreated patients with hodgkin 's disease after stimulation with polyclonal b cell activators and suggest that the in vitro abnormalities may be , at least in part , the result of a preexisting in vivo activation of lymphocytes in hodgkin 's disease patients .
C0024264
lymphocytes
C0019829
hodgkin 's disease