it is demonstrated that the difference with respect to netropsin binding with b-dna , where it occurs specifically in the minor groove of at sequences , is due to the differences in the distribution of the electrostatic molecular potential generated by these different types of dna : this potential is sequence dependent in b-dna ( located in the minor groove of at sequences and the major groove of gc sequences ) , while it is sequence independent and always located in the major groove in a-rna .
C0919262
b-dna
C0012854
dna