similarity of the morphological picture of gouty nephropathy and primary glomerulonephritides in which purine antagonists turned out to be effective , a positive effect of azathioprine ( az ) and 6-mercaptopurine ( mp ) on purine metabolism , and changes in immunity indices revealed in gout ( hyperproduction of immunoglobulins and circulating immune complexes ) necessitates the use of antimetabolites in combined therapy of gout patients with proteinuric and latent types of nephropathy .
C0004482
azathioprine
C0000618
purine