59fe excretion studies in response to different doses ( 4-9 mg ) of three n-substituted 3-hydroxypyrid-4-one chelators , ( 1,2-dimethyl-3-hydroxypyrid-4-one , 1-ethyl-2-methyl-3-hydroxypyrid-4-one , 1-propyl-2-methyl-3-hydroxypyrid-4-one ) , and desferrioxamine in iron overloaded 59fe lactoferrin labelled mice ( 40 +/- 4 g ) have shown that the former chelators , when administered intraperitoneally and intragastrically , caused comparable 59fe excretions to intraperitoneal desferrioxamine of equivalent doses .
C0282193
iron overloaded
C0011145
desferrioxamine