the detection of a familial translocation , t ( 10 ; 18 ) ( p12 ; q22 ) , has made possible the observation in type and countertype of two related persons with opposite chromosomal imbalance : trisomy 18q22 -- -- 18qter with monosomy 10p12 -- -- 10pter in one of the two and monosomy 18q22 -- -- 10pter in the other .
C0008633
chromosomal
C1520259
10p12