in studies designed to establish proper dosage for immunization and to reveal the roles of the liposomal phospholipid to toxoid mass ratio , gel-liquid crystalline transition temperatures ( tc ) of the liposomal phospholipids and mode of antigen incorporation into liposomes on immune responses , animals were injected intramuscularly with various amounts of the toxoid , free , entrapped in multilamellar dehydration-rehydration vesicles ( drv ) or covalently linked to the surface of multilamellar vesicles ( mlv ) prepared by the classical procedure .
C0020971
immunization
C0184661
procedure