however , since punctate hyperkeratotic lesions on the palms , soles and others may , though rarely , undergo malignant transformations , new lesions of bowen 's disease may further occur and these lesions may develop to invasive squamous cell carcinoma , physical examinations of the workers exposed to arsenic should be continued and careful observation of them is necessary for the future .
C0006079
bowen 's
C0007137
squamous cell carcinoma