addition of phorbol myristate acetate to macrophages in the presence of calcium ionophore ( a23187 ) at a concentration which alone did not stimulate arachidonate metabolism resulted in a synergistic increase ( 50-fold ) in leukotriene c4 synthesis compared to phorbol ester or a23187 alone .
C0039654
phorbol myristate acetate
C0031586
phorbol ester