at 1 , 2 , 4 , 6 , 8 , 12 , 24 and 48 h following dosing , rats were killed , and brains , spleens , hearts and adrenal glands were excised and analyzed for concentrations of neurotransmitters and metabolites using high-performance liquid chromatography with electrochemical detection .
C0006104
brains
C0086045
concentrations