like normal adrenocortical cells , tra cells were capable of 20alpha-reduction and delta5-3-beta-dehydrogenation of [ 4-14c5pregnenolone but , in contrast to untransformed cells , they did not respond to variables in culture conditions by qualitative changes in pregnenolone metabolism , did not produce deoxycorticosterone or corticosterone , and secreted progesterone , a hormone not recovered from untransformed cultures .
C0007634
cells
C1327616
secreted