since the in vitro production of trypomastigote stages of trypanosoma cruzi in cell culture is frequently limited by ( 1 ) host cell overgrowth and ( 2 ) by the unequal redistribution of parasites after cell division resulting in asynchronous release of trypomastigotes , a culture system was devised in which host cell mitosis was inhibited by irradiation prior to parasite infection .
C0007590
cell division
C0026255
mitosis