further , the recent report from this laboratory that centrally administered bradykinin specifically augments rat brain prostaglandin e2 levels , together with the proposed role of central prostaglandins as modulators of central synaptic transmission , suggests that bradykinin-induced catalepsy is mediated and modulated through pge effects on serotonergic , cholinergic , and dopaminergic neurotransmitter systems .
C0033554
prostaglandins
C0033559
pge