nevertheless , the cytoskeleton-bound protease in situ , i.e . before its extraction form the cytoskeleton by 0.6 m kcl , preferentially degraded the 160-kda component in the presence of 0.1-0.2 mm ca2+ , suggesting that a proper locational relation of this enzyme to the neurofilament structure is a prerequisite to its preference for the 160-kda component .
C0010853
cytoskeleton
C0027834
neurofilament