an allosteric model is presented that provides a simple explanation for the low population of triply ligated species , relative to the other species , in the oxygenation of human hemoglobin tetramers as found in high-concentration studies [ gill , s. j. , di cera , e. , doyle , m. l. , bishop , g. a. , & robert , c. h. ( 1987 ) biochemistry ( preceding paper in this issue ) ] .
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