most of the increases of tubule cell ca2+ produced by hypoxia and atp were accounted for by pools which could be rapidly removed by exposure of tubules to egta and the uncoupler carbonyl cyanide m-chlorophenyl hydrazone without concomitant use of digitonin , suggesting that the changes of ca2+ predominantly reflect sequestration by mitochondria in severely damaged cells or mitochondria already released to the medium from them .
C0007634
cells
C0026237
mitochondria