the endocytotic response to pma shares several characteristics with endocytosis induced by immunochemical aggregation of surface-bound monomeric ige : the rates of internalization both have a t1/2 of about 5 min , a maximum of 35 % of the surface-bound ige can be endocytosed by the action of pma ( 50 % by receptor aggregation ) , endocytosis is sustained for at least up to 60 min , neither stimulus requires extracellular ca2+ and endocytosis induced by either stimulus is an active process , i.e. , is dependent on temperature and cellular energy .
C0014139
endocytosis
C0007634
cellular