we have also defined conditions under which enhanced anti-tumor immunity can be obtained by pre-inducing potent helper t cell activity reactive to a certain antigenic determinant such as trinitrophenyl ( tnp ) residue of muramyl dipeptide ( mdp ) -derivatives as hapten , and immunized with tumor cells coupled with the corresponding haptenic determinant .
C0003316
antigenic determinant
C0018593
haptenic