to investigate the toxic potential of rapid intravenous quinine administration in severe malaria , the pharmacokinetic properties of low-dose quinine dihydrochloride injection ( 4 mg/kg body weight , equivalent to 3.3 mg base/kg ) followed one hour later by infusion of 16 mg/kg over 3 h were studied in 7 patients with cerebral malaria .
C0034417
quinine
C0024530
malaria