high-density-lipoprotein cholesterol concentrations in both groups of renal patients were significantly lower than control values ( p less than 0.01 ) , and their ratios of low-density-lipoprotein to high-density-lipoprotein cholesterol were significantly higher ( p less than 0.01 ) than those observed in both randomly selected controls and in controls matched for plasma lipid levels ( control , 2.4 +/- 1.2 , dialysis , 3.7 +/- 2.1 , and transplant , 5.4 +/- 2.3 mg per 100 ml [ mean +/- s.d . ] ) if , as experimental evidence suggests , high-density lipoprotein retards the development of atherosclerosis , and low-density lipoprotein has opposite effects , the higher ratio of low-density-lipoprotein to high-density-lipoprotein cholesterol found in chronic-dialysis and renal-transplant patients may be related to their premature morbidity and mortality from cardiovascular causes .
C0022646
renal
C0022671
renal-transplant