two predictions can be made and tested concerning the role of ia determinants in cytolytic systems and the role , if any , of i-region- specific ctl in regulating the immune response : ( a ) that if as we and others have shown , certain ia specificities can serve as a third series of major histocompatibility antigens , then ia antigens should be susceptible to the same types of antigenic modifications as h-2k- or h-2d-coded structures and thus serve as targets for ctl directed against modified-self in selected systems ;
C0019628
histocompatibility antigens
C0019630
ia antigens