total heme catabolism has been studied through measurement of the endogenous production of carbon monoxide ( vco ) in 8 patients with hemolysis , 7 with hypoproliferative anemia , 10 with refractory anemia and hypercellular bone marrow and 7 with splenomegaly , 6 of whom had myeloid metaplasia .
C0002893
refractory anemia
C1334068
hypercellular bone