this investigation has shown that ( a ) neonates of cdca fed dams have a significantly greater pool of cdca , suggesting maternal-to-fetal transfer of dihydroxy bile acids , ( b ) neonatal cholesterol-7 alpha-hydroxylase activity and total tissue bile acid pools are not significantly altered by increased pool of cdca , and ( c ) no hepatotoxic effects on maternal , neonatal , and postnatal livers were evident with gestational feeding of cdca at the 0.25 % level in the rat .
C0021289
neonates
C0028128
no