( 2 ) increased bone turnover affecting bone resorption [ fasting hydroxyproline excretion , lac 2.22 +/- 0.12 mumol/liter gf ( mean +/- sem ) , con 1.19 +/- 0.04 , p less than 0.001 ] and affecting bone formation ( plasma alkaline phosphatase , lac 81.9 +/- 2.5 iu/liter , con 53.5 +/- 2.7 , p less than 0.001 , and serum osteocalcin , lac 14.0 +/- 0.7 microgram/liter , con 7.3 +/- 0.4 , p less than 0.001 ) ;
C0032105
plasma
C0229671
serum