the main haemostasis changes observed in a screening study performed in 40 patients who underwent an open heart surgery with extracorporeal circulation ( ecc ) are : a significant drop in platelet count from the onset of the ecc to the third postoperative day , a decrease of platelet retention and aggregation during ecc with an 8-day persistently increased heparin-neutralizing activity in plasma but not in serum , a moderate decrease of plasma factors i , ii , vii-x , x and xiii and a more important drop in factor v which disappears 24 h after ecc , a transitory increase of fibrinolysis during ecc and the lack of fdp elevation in the serum .
C0032105
plasma
C0229671
serum