excellent clinical responses , as judged by hematologic parameters , were observed among patients whose leukemic cells were susceptible to rd alpha 2-ifn with respect to trs formation in vitro . from these findings , we propose that the induction of trs formation , in combination with the increase of als , may be a morphologic expression of a direct antitumor action of ifn on malignant cells .
C0021734
rd alpha 2-ifn
C0002199
a