antibodies against an antigen in the centromere region of chromosomes ( centromere antibodies ) were demonstrated by indirect immuno-fluorescence on hep-2 cells in 18 patients ( 17 % ) and antibodies against scl-70 nucleoprotein ( scl-70 antibodies ) by gel precipitation with soluble nuclear extracts ( ena ) in 21 patients ( 20 % ) .
C0007709
centromere
C0007634
cells