following doses 4 and 13 , mean serum half-lives were 2.8 and 2.9 h , volumes of distribution 0.15 +/- 0.04 l/kg and 0.17 +/- 0.041 l/kg and plasma clearance values 1.320 +/- 0.50 ml/min/kg and 1.096 +/- 0.48 ml/min/kg , respectively .
C0229671
serum
C0032105
plasma