electron microscopic examination of the frontal cortex of a patient with amyotrophic lateral sclerosis ( als ) with 14-year prolongation of life by artificial ventilation of the lungs revealed heretofore undescribed cytoplasmic virus-like inclusions in neurons and glial cells as well as changes in the granular endoplasmic reticulum in astrocytes consisting of large accumulations of ribosomes in which regular arrays were frequently observed .
C0230779
granular endoplasmic reticulum
C0035553
ribosomes