3 propranolol ( 0.1 mg/kg i.v . ) significantly antagonized the isoprenaline-induced tachycardia ( beta 1 mediated ) and fall in diastolic blood pressure ( beta 2 mediated ) while metoprolol ( 0.2 mg/kg i.v . ) antagonism was confined to beta 1 mediated responses .
C0022245
isoprenaline
C0039231
tachycardia