indomethacin ( im ) , a potent inhibitor of prostaglandin synthetase , significantly inhibited implantation in rats when administered at a single subcutaneous dose of 15 mg/kg on day 2 or 3 of pregnancy or at a dose of 800 micrograms administered intraluminally in the uterus on day 4 of pregnancy .
C0021246
indomethacin
C0032961
pregnancy