this condition is apparently associated with mental and psychomotor retardation , widely spaced eyes , flat nasal bridge , low set ears , down-turned mouth , micrognathia , loose skin at the nape , widely spaced nipples , simian creases , clinodactyly , abnormalities of the genitourinary system , alterations in the sacrococcygeal region , and deformities of the lower limbs .
C0226896
mouth
C0025990
micrognathia