captopril was administered to acute ( 8 to 14 days after unilateral renal artery constriction ) and chronic ( 71 to 127 days after the constriction ) two-kidney goldblatt hypertensive dogs , and to normotensive ones for 21 days ( oral administration of 10 , 20 and 40 mg/kg/day , consecutively each 7-day period ) .
C0035067
renal artery
C0022646
kidney