in 10 young ( mean age 27.7 years ) subjects with mild asthma ( fev1 greater than 70 % predicted ) , we evaluated the bronchodilator and protective efficacy of 5 , 10 , and 20 mg of cetirizine against bronchospasm induced by histamine inhalation ( 0.03 to 20 mg/ml ) in comparison with placebo and hydroxyzine , 25 mg , using a random , double-blind crossover design .
C0055147
cetirizine
C0020404
hydroxyzine