including six patients with `` '' mid-dose '' '' dyskinesias and six others with `` '' onset and end of dose '' '' dyskinesias , correlation between the circumstances of onset of abnormal movements and plasma concentrations of dopa and o-methyl-dopa , after administration of a dose of l-dopa + idc , gave the following results : 1 ) mid-dose dyskinesias appeared with the highest plasma concentrations of dopa , at the maximum therapeutic effect ;
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and o-methyl-
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of