to help identify cellular changes that occur during the development of gallbladder cancer , we obtained gallbladder tissue , serum , and bile specimens from 20 patients with invasive adenocarcinoma of the gallbladder , three with high-grade dysplasia ( carcinoma in situ ) , six with low-grade dysplasia , 12 with hyperplasia , and 10 with acute or chronic cholecystitis .
C0016976
gallbladder tissue
C0085694
chronic cholecystitis