these findings demonstrate that after a week-long course of high-dose prednisone therapy : ( 1 ) a significant reduction occurs in bronchial sensitivity to inhaled methacholine in the asthmatic child , and ( 2 ) the degree of diminution in airway sensitivity to methacholine is inversely related to the patient 's baseline status of airway obstruction .
C0032952
prednisone
C0004096
asthmatic