effects of spironolactone , canrenone and canrenoate-k on adrenal cytochrome p450 ( p450 ) and corticosteroid biosynthesis were examined by studying difference spectra , p450 reduction and corticoid hydroxylation in mitochondrial preparations isolated from zona fasciculata and zona glomerulosa of bovine adrenals and from adrenal adenoma and hyperplastic adrenal cortex removed from patients with hyperaldosteronism .
C0001625
adrenals
C0206667
adrenal adenoma