the patients with down syndrome had a lymphocytosis in blood with high counts of t ( and b ) cells , but with impaired effector function of t cells as judged by anergy to dinitrochlorobenzene , low responsiveness to ubiquitous antigens which elicit delayed-type hypersensitivity reactions , and low mitogenic activity of non-stimulated and phytohaemagglutinin-stimulated lymphocytes in culture .
C0206120
anergy
C0003320
antigens