in efforts to determine whether stimulation of na+/h+ exchange by phorbol esters is coupled to induction of cellular differentiation , we found that 1 ) amiloride , a frequently used inhibitor of na+/h+ exchange , rapidly inhibits phorbol ester-stimulated protein phosphorylation in vivo and protein kinase c-mediated phosphorylation in vitro , both with potency similar to that with which amiloride inhibits na+/h+ exchange ;
C1516343
induction
C0007634
cellular