a case is presented with early-onset polyarthritis involving both large and small joints , prolonged fever , skin rash , hepatosplenomegaly , persistent cerebro-spinal fluid pleocytosis , brain atrophy , macrocephaly with ventricular dilatation , a persistently open fontanelle , lymphadenopathy , subcutaneous nodules , developmental delay , failure to thrive , persistent hypochromic microcytic anemia , leukocytosis with shift to the left , early thrombocytopenia followed by thrombocytosis , high erythrocyte sedimentation rate , elevated immunoglobulin level , and vasculitis involving several organs .
C0162323
polyarthritis
C0022417
joints