it was observed that in surely in situ forms ( atypical metaplasia , severe dysplasia and carcinoma in situ ) there is a clear prevalence of cases with a minimal or absent reaction , while in the potentially invasive carcinoma and in the microcarcinoma there is a predominance of cases with a marked reaction , as if the first biological modifications that lead to invasion were accompanied by a massive activation of the immune defence mechanisms .
C0334048
severe dysplasia
C0007099
carcinoma in