preparation of calmodulin-free tryptophan hydroxylase by affinity chromatography on fluphenazine-sepharose 4b yields an enzyme that is no longer activated by atp-mg2+ , whereas the readdition of calmodulin to a calmodulin-free enzyme restores the responsiveness of tryptophan hydroxylase to atp-mg2+ .
C0020364
hydroxylase
C0041252
tryptophan hydroxylase