as a consequence , the uptake of iododeoxyuridine , a substrate of thymidine kinase , can be substantially increased by 5'-aminothymidine . in this study the phosphorylation , uptake , and cytotoxicity of iododeoxyuridine was markedly enhanced by 5'-aminothymidine in three human bladder cancer cell lines , t24 , ht1197 and 647v .
C0040078
thymidine kinase
C0031715
phosphorylation