in lymphoblasts , no qualitative or quantitative differences were observed between these isolates and human t-cell leukemia virus iiib ( htlv-iiib ) for ( 1 ) release of p24 antigen reverse transcriptase , and infectious virus , ( 2 ) induction of typical cytopathic effects ( cell syncytia in 3-10 % of cells ) and cell lysis , ( 3 ) frequency of infected cells ( 5-20 % of pbmc ) as detected by in situ hybridization for hiv rna , ( 4 ) down-modulation of t cell plasma membrane cd4 , and ( 5 ) site of progeny virion assembly and budding ( plasma membrane only with no intracytoplasmic accumulation of virus ) .
C0007634
cells
C1321301
pbmc