features that are associated with an unfavorable fetal/infant prognosis are : maternal age less than 30 years , primiparity , leg primary site , disease onset greater than 3 years prior to pregnancy , node-1 metastatic status prior to pregnancy , m4 status in third trimester , birth at greater than 36 weeks ' gestation , male sex .
C0032961
pregnancy
C0032981
third trimester