based upon these observations , we suggest that fructose feeding produces hypertriglyceridemia by directly stimulating hepatic vldl-tg secretion , as well as by producing insulin resistance and hyperinsulinemia , and that it is the combined effect of these two separate actions which accounts for the magnitude of fructose-induced hypertriglyceridemia .
C0021655
insulin resistance
C0020459
hyperinsulinemia