a sustained-release theophylline preparation ( theo-dur sprinkle ) was evaluated in young asthmatic patients aged 1 to 6 years and receiving a daily dose of 23.4 +/- 2.0 mg/kg ( mean +/- sd ) to determine , on the basis of serial serum concentrations obtained over a 12-hour dosing interval at steady state , the suitability of such a product in patients likely to metabolize the drug very rapidly .
C0039771
theophylline
C0004096
asthmatic