novel analogues of the class iii antiarrhythmic agent 1- [ 2-hydroxy-2- [ 4- [ ( methylsulfonyl ) amino ] phenyl ] ethyl ] -3-methyl-1h- imidazolium chloride , 1 ( ck-1649 ) , were prepared and investigated for their class iii electrophysiological activity on isolated canine cardiac purkinje fibers and ventricular muscle tissue .
C0018787
cardiac
C0018827
ventricular