this observation supports the suggestion of a possible role of procarbazine-induced o6-methylguanine in the pathogenesis of acute nonlymphocytic leukemia appearing after treatment with chemotherapeutic protocols which include procarbazine , based on the finding of low lymphocyte agt levels in patients with such therapy-related neoplastic disease ( sagher et al. , cancer res. , 48 : 3084-3089 , 1988 ) .
C0027651
neoplastic disease
C0006826
cancer