in order to eliminate the first pass through the liver where the drug is deactivated , 80 mgs verapamil was given in sublingual way in a ) 10 patients with supraventricular tachycardias where in 7 instances sinus rhythm was obtained after 15-30 minutes , b ) in 18 patients with atrial fibrillation and in 5 with atrial flutter with rapid ventricular rate , where a significant slowing down of ventricular rate was obtained after 20 minutes .
C0042523
verapamil
C0004238
atrial fibrillation