although bacterial endotoxin/lipopolysaccharide is a potent stimulus for the synthesis and release of il-1 and il-6 in vitro , specific neutralization of cachectin/tnf in vivo with mab pretreatment significantly attenuated both the il-1 beta and the il-6 responses despite fulminant overwhelming bacteremia .
C0021755
il-1
C0021753
il-1 beta