the administration of theophylline ( 120 mg/kg.day , 14 wk ) to the drinking water of female balb/c mice after treatment with 1,2-dimethylhydrazine ( dmh ) ( 30 mg/kg.sc , 1/wk , 14 wk ) resulted in both an increase in number of colon carcinoma and increases in ornithine decarboxylase ( odc ) activities and polyamine ( pa ) levels in colon tissue .
C0699790
of colon carcinoma
C0009368
colon