oral administration of ethanol ( 20 % v/v ) to male sprague-dawley rats for different periods of time up to 28 weeks resulted in profound reductions of acetylcholine content , in vitro synthesis and release of acetylcholine , choline uptake , activities of choline acetyltransferase , acetylcholinesterase and pyruvate decarboxylase , content of noradrenaline , serotonin and , to a lesser extent , dopamine throughout the brain .
C0423896
content
C0006104
brain