between 1974 and 1977 , a total of 254 patients with stages t1-3a , n0-1 , and m0 operable breast cancer ( node negative and node positive , stratified ) were randomized to either modified radical mastectomy alone or the same surgery and adjuvant chlorambucil , methotrexate , 5-fluorouracil ( lmf ) plus bcg .
C0008163
chlorambucil
C0065134
lmf