by means of immunofluorescence using sera against three classes of human immunoglobulins ( igg , igm , iga ) , localization of the components ( or one of the components ) responsible for reaction of sera from patients with rheumatoid arthritis ( ra ) with connective tissue antigens was found to be in the cytoplasm of different kinds of cell elements of the connective tissue present in joints .
C0003873
rheumatoid
C0022417
joints