in addition , lung contents of the polyamines , putrescine , spermidine , and spermine were greater in hypoxic animals than in controls . alpha-difluoromethylornithine ( dfmo ) , an inhibitor of polyamine synthesis , attenuated the hypoxia-induced elevations in lung putrescine and spermidine content and blunted the increases in pulmonary arterial pressure and medial thickness .
C0037874
spermine
C0037871
content