in a chronic conscious rat , histopathological findings show that the bladder tissue at 2 days after implantation of the catheter to the bladder showed experimental cystitis characterized by severe edema in the submucosa and an increase in prostaglandin e2 content , which is thought to stimulate directly and/or indirectly the capsaicin-sensitive sensory fiber in the afferent branch of the micturition reflex , and there was hyperreflexia characterized by decreases in both bladder capacity and urine volume .
C0005682
bladder
C0042034
micturition