in a single-dose , cross-over study , captopril ( 1 mg/kg ) and nifedipine ( 20 mg ) significantly reduced blood pressure in 12 patients with moderate essential hypertension , but the mean maximum arterial pressure reduction was faster and greater with nifedipine than with captopril ( -23 +/- 2 % at 37 +/- 15 min and -17 +/- 1 % at 86 +/- 25 min , respectively ) .
C0020649
reduced blood pressure
C0028066
nifedipine