in liver , dose-related decreases were observed in the activities of the mitochondrial enzymes , delta-aminolevulinic acid ( ala ) synthetase and heme synthetase , and of the cytoplasmic enzyme , ala dehydratase , to 51 , 48 , and 35 % of levels seen in untreated controls , respectively .
C0026237
mitochondrial
C0010834
cytoplasmic