four groups of 50 rats were treated with two different doses of sodium 2-mercaptoethane sulfonate ( mesna , uromitexan ) ( single doses of 5 or 15 mg/kg body weight ) , or disodium 2,2'-dithio-bis-ethane sulfonate ( dimesna ) ( single doses of 12 or 35 mg/kg body weight ) , and the effect on carcinogenicity by cyclophosphamide was investigated .
C0000294
mesna
C0678115
uromitexan