nuclei isolated from potentially active noninduced cells and transcriptionally active induced mel cells were treated with dnase i at concentrations which did not digest the beta-globin gene , followed by repair using a typical nick translation reaction during which a cleavable biotinylated nucleotide analog , 5- [ n-biotinamido ) hexanoamido-ethyl-1,3-dithiopropionyl -3-aminoallyl ] -2'- deoxyuridine 5'-triphosphate ( bio-19-ss-dutp ) , was inserted into dna sequences .
C0007610
nuclei
C0007634
cells