the rate constant of enzyme activation ( kon ) was measured using the gtp analog guanylimidodiphosphate ( gpp ( nh ) p ) , and the rate constant of enzyme deactivation ( koff ) was determined using the guanosine diphosphate analog guanosine 5'-0- ( 2-thio ) -diphosphate ( gdp beta s ) .
C0018353
gtp
C0018366
gpp ( nh ) p