since a single po dose of methaqualone failed to produce any alteration in the rate of metabolism of acetylsalicylic acid , procaine , p-nitrophenylacetate , acetanilid , and butyrylcholine within 20 hr , it may be interpreted that the stimulation of acetylsalicylic acid and acetanilid metabolism is possibly due to selective enhanced de novo synthesis of the enzymes/isozymes necessary for the hydrolysis of the two drugs .
C0014442
enzymes
C0022173
isozymes