three phenomena have also been incriminated to explain the defect of immunosurveillance in brain tumour patients : 1 ) the synthesis by tumour cells of a protective mucopolysaccharidic coat , 2 ) the secretion by these cells of specific immunosuppressive factors related to cytokines , 3 ) the isolation of cns maintained by the blood-brain barrier which regulates the circulation of immunocompetent cells between the intra- and extracerebral compartments .
C1327616
secretion by
C0007634
the