when diarrhea was induced by intragastric infusion of 2700 ml of balanced electrolyte solution over 90 min , oral administration of 0.3 mg of clonidine reduced the volume of rectal effluent by 48 % ( from 1233 +/- 62 to 640 +/- 77 ml , p less than 0.001 ) , a clear-cut antidiarrheal effect .
C0011991
diarrhea
C0009014
clonidine