exposure of synchronized c3h10t1/2 ( clone 8 ) cell populations of various sizes to n-methyl-n'-nitro-n-nitrosoguanidine ( mnng ) at a concentration of 2 micrograms/ml for 30 min at 24 h after release from confluence-induced arrest of proliferation produced neoplastic transformation ( formation of foci of morphologically altered cells ) by a random but episodic process in a small fraction of the cells at risk soon after treatment .
C0007634
cell
C0007613
process