therefore the results demonstrate two distinct effects of igg bf : ( 1 ) an isotype-specific suppression of cells producing igg , demonstrated by the parallel decrease of igg cc and igg pfc , and ( 2 ) a blocking of the late stages of b cell maturation evidenced by the discrepancy between normal or elevated ig cc and decreased ig pfc of the igm and iga classes .
C1511002
b cell maturation
C0007634
pfc