in the rabbit heart and in human atria results were quite different : cimetidine and ranitidine were virtually ineffective up to the maximum concentration tested ( 3 x 10 ( -3 ) m ) , oxmetidine and compound skf 93479 had a negative inotropic and chronotropic effect starting from concentrations of 3 x 10 ( -6 ) -10 ( -5 ) m .
C0018787
heart
C0018792
atria