in the clinical studies , a double blind crossover comparison of oral propafenone ( 300 mg ) , propranolol ( 40 mg ) and placebo indicated significant antagonism of chronotropic response to isoproterenol 2 hr postdose with dose ratios of 4.1 +/- 1.3 ( mean +/- s.e.m . ) for propafenone and 16.8 +/- 5.1 for propranolol .
C0033429
propafenone
C0033497
propranolol