evidence that the cholesterol was actually a component of chromatin includes ( a ) the constancy of the amount ( 1.30 +/- 0.14 mug per mg dna ) , ( b ) the striking difference in the ratio of free ( i.e . unesterified ) to esterified cholesterol between that in chromatin and that in membrane , and ( c ) the rapid and marked changes which occurred in this ratio during the circadian cycle in chromatin but not in membranes .
C0008377
cholesterol
C0008387
esterified cholesterol