a change of the isoelectric spectrum of the hbs-antigen and its tropism in affine chromatography to the antibodies against serum proteins possibly depended both on the nonhomogeneity of the antigenic determinants included into the composition of the antigen , and on the presence of the hbs-antigen -- hbs-antibody or hbs-antigen -- serum proteins complexes .
C0003316
antigenic determinants
C0003320
antigen