spiramycin was less active than erythromycin in vitro against sensitive strains of staphylococcus aureus , but was as effective against staphylococcal infections in mice when the drugs were administered immediately after infection : spiramycin was relatively more effective in prophylactic experiments when the antibiotics were administered at 4 or at 6 hr before infection .
C0014806
erythromycin
C0038160
staphylococcal infections