using serum-free waymouth 's mb 752/1 chemically-defined medium , addition of high levels of ascorbic acid ( 300mug per ml ) , hydrocortisone ( 1mug per ml ) and oxygen ( 95 % ) enhanced differentiation in a number of tissues , in particular skin and appendages , tooth germs and bone , while osteoid and dentine production were noticeable promoted .
C0262950
bone
C0682561
osteoid