a meta-analysis of the controlled clinical trials comparing the efficacy of combined lithium-imipramine therapy with each drug alone in the prevention of relapse in patients with unipolar depressive illness shows the combination to be superior to lithium alone ( for any relapse , p less than 0.05 ; for specifically depressive relapse , p less than 0.025 ) and imipramine alone ( for any relapse , p less than 0.025 ; for specifically depressive relapse , p less than 0.05 ) .
C0011581
depressive illness
C0020934
imipramine