in the neonates receiving the drug i.v . for therapeutic reasons , the elimination kinetics appeared to follow a two-compartment open model , with a significant difference in the therminal plasma half-life between premature ( 26.8 +/- 12.2 h ) and full-term newborns ( 13.4 +/- 8.6 h ) .
C0022702
kinetics
C0018517
half-life