subcellular fractionation studies of cells labeled in vivo revealed that the 135,000-dalton protein and part of the 50,000 to 55,000 dalton protein doublet were found in both the nuclear and the cytoplasmic fractions , and thus are good candidates to be components of the ea ( d ) diffuse-type immunofluorescence observed with many ea-positive sera .
C0007634
cells
C0010834
cytoplasmic