to characterize the blood pressure and heart rate effects of atrial natriuretic peptide ( anp ) in the brain , we administered 20 micrograms/kg of atriopeptin iii in 5 microliters of 0.9 normal saline into the fourth ventricle of awake , freely moving , spontaneously hypertensive ( shr ) and normotensive wistar-kyoto ( wky ) rats .
C0006104
brain
C0149556
fourth ventricle