receptor-mediated breakdown of ptdins ( 4,5 ) p2 produces two cellular signals , ins ( 1,4,5 ) p3 , which can release intracellular ca2+ , and diacylglycerol , which activates a ca2+- and phospholipid-dependent protein kinase ( protein kinase c ) .
C0037083
cellular signals
C0033634
protein kinase c