both th1165a ( 5 , 10 , 15 and 20 mg ) and metaproterenol administration caused significant bronchodilation of rapid onset ( 30 minutes ) , but the bronchodilator effect of th1165a ( 10 , 15 , and 20 mg ) was greater and lasted longer ( six hours vs three hours ) than that of metaproterenol .
C0029193
administration
C1371299
bronchodilation