bovine aorta smooth muscle cells ( smc ) incubated with a tumor-promoting phorbol ester , 12-o-tetradecanoylphorbol-13-acetate ( tpa ) , released increased levels of prostaglandin i2 [ measured as its stable hydrolytic product , 6-keto-prostaglandin f1 alpha ( 6-keto-pgf1 alpha ) ] , and this response was inhibited by all-trans-retinoic acid ( ra ) at concentrations as low as 17 nm .
C0031586
phorbol
C0039654
12-o-tetradecanoylphorbol-13-acetate