biological evaluations of the three compounds consisted of studies of their effects on enzyme inhibition [ ( dihydrofolate reductase ( ec 1.5.1.3 ) and thymidylate synthase ) ] , l1210 cell growth inhibition , cellular membrane transport with various murine cell types ( l210 , s180 , ehrlich , and epithelial ) , in vivo ( mice ) activity vs .
C0007595
cell growth
C0007634
cellular