activation of the voltage-dependent ca2+ channels by the dihydropyridine ca2+-agonist [ methyl 1,4-dihydro-2,6-dimethyl-3-nitro-4- ( 2-trifluoromethylphenyl ) -pyridine- 5-carboxylate ( bayk8644 ) ] stimulated lh release , 36 % of the gnrh ( 100 nm ) response being reached by 10 ( -8 ) m of the drug , both [ ca2+ ] i elevation and gnrh-induced lh release were inhibited similarly ( 40-50 % ) by the dihydropyridine ca2+-antagonist nifedipine .
C0012315
dihydropyridine
C0028066
nifedipine