the ca2+-dependent protein kinase responsible for phosphorylation of the 100 kda protein appeared to be a calmodulin ( cam ) -requiring enzyme in that it could be inhibited in cytosol extracts by trifluoperazine ( ic50 6-16 microm ) and that exogenous cam was necessary for 100 kda phosphorylation in cam-depleted cytosol .
C0033640
protein kinase
C1158886
phosphorylation