the inhibition by suramin of dna polymerase alpha from kb cells and rauscher murine leukemia virus ( rlv ) reverse transcriptase was due to competition with the respective template primer ( activated dna for alpha polymerase and ( ra ) n. ( dt ) 12-18 for reverse transcriptase ) for the template.primer-binding site of the enzyme , while the inhibition of dna primase and e.coli rna polymerase was due to competition with the ribonucleoside triphosphate substrate .
C0058594
primase
C0035681
rna polymerase