the blockade appears to be competitive , and voltage-clamp experiments on an identified cockroach motorneuron indicate that the actions of kappa-bungarotoxin are not dependent on membrane potential . alpha-bungarotoxin is also a potent antagonist at the cockroach central nicotinic receptor , and binds ( kd = 4.3 nm ) to a nicotinic site in cockroach nervous tissue . kappa-bungarotoxin recognizes this invertebrate nicotinic site with high affinity ( ki = 27 nm ) .
C0026609
motorneuron
C0027757
nervous tissue