when the mnu-treated cells are cultured in the presence of 3-amino-benzamide , a specific inhibitor of poly ( adp-ribose ) synthetase , the depression in rna synthesis is prevented , and percentage of ao positive cells as well as numbers of ao chromatin interaction products per single cell nucleus are also completely recovered as compared to those in the untreated cells .
C0008546
chromatin
C0007634
cells