it eliminates the need for preliminary titrations , is economical , provides information about the slope of the log-dose response lines and , therefore , of the validity of the assay , and yields limits of error of potency from the internal evidence of the assay.a study has been made of the effects of avidity , combining power , toxicity and buffering on the assay of diphtheria toxins against the international standards for both diphtheria antitoxin and schick-test toxin.all the toxins assayed against the standard toxin , whatever their other properties might be , gave log-dose response lines of similar slope provided that they were diluted in buffered physiological saline .
C0012546
diphtheria
C0012547
diphtheria