therefore , aq-a39 differed from verapamil in that ( i ) aq-a39 was a more selective bradycardic agent in both beta-adrenergically stimulated and nonstimulated preparations and ( ii ) aq-a39 was more effective in reducing isoproterenol-elevated heart rate compared with basal heart rate .
C0428977
reducing
C0022245
isoproterenol