mc1 negative and positive populations were not significantly different in any of a variety of clinical and laboratory variables including age , sex , disease duration , age at onset , hours of morning stiffness , functional class , joint count , presence of subcutaneous nodules or bony erosions , frequency of side effects to gold or d-penicillamine , sedimentation rate , and antinuclear antibody .
C0018026
gold
C0030817
penicillamine