alpha-difluoromethylornithine ( rmi 71,782 ) , a specific irreversible inhibitor of the first step in polyamine biosynthesis , that is , the formation of putrescine from ornithine by ornithine decarboxylase , cures mice infected with a virulent , rodent-passaged strain of trypanosoma brucei brucei .
C0002260
alpha-difluoromethylornithine
C0029282
ornithine