when administered for 1 or 3 consecutive days , iflra/d , which exhibited the highest antiviral activity in murine l cells , caused a dose-dependent decrease in cytochrome p-450 content and in the rate of metabolism in vitro of benzo [ a ] pyrene , hexobarbital , 7-ethoxycoumarin , benzphetamine , and zoxazolamine .
C0010762
cytochrome p-450
C0025519
metabolism