injection of anti-kidney serum to rats significantly increased the urinary protein excretion , serum levels of fibrinogen , cholesterol and immune complex , significantly decreased serum immunoglobulin g and complement levels , and caused histopathological changes such as detachment of endothelial cells from basement membrane , thickening of basement membrane , fusion of foot process and increase in hyaline cast in renal tubuli .
C0229671
serum
C0009498
complement