the central mechanism responsible for the potentiation by antidepressant drugs of analgesia induced by morphine , was explored by measuring the levels of various neuropeptides ( met-enkephalin , leu-enkephalin , dynorphin , substance p and cholecystokinin-like materials ) and the density of delta and mu opioid binding sites in the spinal cord of rats treated for 14 days with amoxapine ( 10 mg/kg i.p. , daily ) or amitriptyline ( 10 mg/kg i.p. , daily ) .
C0003289
antidepressant drugs
C0002644
amoxapine