the clinical picture is that of long-standing rheumatoid arthritis with severe articular and extraarticular manifestations including splenomegaly , depression of the blood elements , mild liver function abnormalities , portal hypertension without cirrhosis or portal vein obstruction , an elevated splenic blood flow , and a reduction in portal hypertension by simple splenectomy .
C0037993
splenic
C0037995
splenectomy