in rats given the glycoprotein ( without trichloroacetic acid ( tca ) treatment ) prepared from pronase digests of homologous renal cortex , morphologic changes of proliferative glomerulonephritis were followed ( 3 -- 4 months after injection ) by those of typical membranous glomerulonephritis with an immunofluorescent 'granular ' pattern , but in animals which received the glycoprotein ( with tca treatment ) , the morphologic changes of the kidney were those of proliferative glomerulonephritis with an immunofluorescent 'mesangial ' pattern throughout the whole course .
C0022646
kidney
C0235618
proliferative glomerulonephritis