in dogs anaesthetized with pentobarbitone sodium , bradycardia with hypotension occurred on intracerebroventricular ( i.c.v . ) injection of noradrenaline ( 50-200 mug ) or phenylephrine ( 100-400 mug ) , but tachycardia with hypotension occurred on i.c.v . injection of isoprenaline ( 100-200 mug ) .2 .
C0039231
tachycardia
C0022245
isoprenaline