a cyclic nucleotide-independent protein kinase , which was produced from its proenzyme upon limited proteolysis by a ca2+-dependent protease ( takai , y. , yamamoto , m. , inoue , m. , kishimoto , a. , & nishizuka , y . ( 1977 ) biochem . biophys . res . commun . 77 , 542-550 ) , showed an ability to phosphorylate not only muscle glycogen phosphorylase kinase but also glycogen synthase , resulting in activation and inactivation of the respective enzymes , although the protein kinase was less active than adenosine 3':5'-monophosphate ( cyclic amp ) -dependent protein kinase toward glycogen synthase .
C0597304
proteolysis
C0030946
protease