we conclude that renal cytochrome p-450 is increased in three models in which hepatic cytochrome p-450 contents are decreased ( two-thirds hepatectomy , cholestasis and biliary cirrhosis ) , but remains unchanged in a model of severe liver pathology , in which hepatic cytochrome p-450 content is not modified ( late , post-necrotic cirrhosis ) .
C0023892
biliary cirrhosis
C0023884
liver