of these 79 patients , two thirds have had one or more types of major cns toxicity , including epileptiform seizures ( 35 ) , moderate to severe structural abnormalities ( 24 of 27 evaluated ) , major motor disabilities ( 9 ) , blindness ( 2 ) , cns infection ( 6 ) , cranial nerve palsies ( 2 ) , and intracranial lymphoma ( 2 ) .
C3714787
cns
C0007684
cns infection