administration of propranolol ( 500 mg/l in drinking water ) did not inhibit the development of hypertension for up to 4 weeks or the associated increase in cardiac or aortic weight in doc-salt-treated rats , but did prevent the increase in polyploidy of aortic smooth muscle cell nuclei ( 8.9 +/- 0.9 % in propranolol-treated rats compared to 7.8 +/- 0.3 % in normotensive controls ) .
C0020538
hypertension
C0033497
propranolol