as the pathogenesis in cystic fibrosis ( cf ) has been considered to lie in a disturbance in the behavior of secretions , particularly mucins , from exocrine glands , it has been proposed that an alteration in surface topography ( form , number or distribution of microvilli or blebs ) of epithelial cells lining ducts could impair distribution leading to retention of mucus leading to the clinical phenotype .
C0026682
mucins
C0014597
epithelial cells