repeated administration of an intravenous immunoglobulin containing antibody to hepatitis b e antigen ( anti-hbe ) and antibody to hepatitis b core antigen ( anti-hbc ) but free of antibody to hepatitis b surface antigen ( anti-hbs ) before and after the inoculation of 10 ( 4.9 ) 50 % chimpanzee infective doses of hepatitis b virus ( hbv ) markedly prolonged the incubation period of hbv in experimentally infected chimpanzees .
C0021027
immunoglobulin
C0003241
antibody