there is substantial evidence that a ca2+-activated myosin light chain kinase/phosphatase system regulates smooth muscle contraction , and adelstein et al . have shown that the catalytic subunit of cyclic amp-dependent protein kinase plays a part in this regulation , by phosphorylation of the high molecular weight subunit of the light chain kinase , which results in a decrease in the activity of the kinase .
C0031715
phosphorylation
C0031727
kinase