these data suggest that the intravenous administration of pharmacologic doses of rt-pa in patients with pulmonary embolism produces both fibrinolysis and fibrinogenolysis , successful thrombolysis in these patients is associated with a preponderance of fibrinogenolysis over fibrinolysis , the xdp/fdp ratio is a useful indicator of fibrinolytic specificity , and in patients with acute pulmonary embolism the endogenous fibrinolytic pathways are activated , albeit ineffectively , as indicated by the increased circulating xdp levels seen in all 24 patients before the administration of rt-pa .
C0034065
pulmonary embolism
C0032143
rt-pa