morphometric analysis of the distribution of ferritin-labeled ligand at em resolution reveals the following sequence of events in the endocytosis of cell surface igm : ( a ) binding of the multivalent ligand in a diffuse cell surface distribution , ( b ) clustering of the ligand-receptor complexes , ( c ) recruitment of clathrin coats to the cytoplasmic surface of the cell membrane opposite ligand-receptor clusters , ( d ) assembly and ( e ) internalization of coated vesicles , and ( f ) delivery of label into a large vesicular compartment , presumably partly lysosomal .
C0015879
ferritin
C1517880
binding