a 22-24 h exposure of mouse pancreatic islets to the phorbol ester 12-o-tetradecanoylphorbol 13-acetate ( tpa ; 0.16 microm ) in rpmi 1640 culture medium ( 8.3 mm-glucose , 0.43 mm-ca2+ ) abolished tpa ( 0.16 microm ) -induced insulin secretion and led to a potentiation of phase 1 and a decrease in phase 2 of glucose-induced insulin secretion .
C0031586
phorbol ester
C0039654
12-o-tetradecanoylphorbol 13-acetate