treatment with naloxone ( 3 mg/kg bolus and 2 mg/kg/hr infusion for 2.5 hours ) , a specific opiate antagonist , during septic shock attenuated the hypotension ( p less than 0.002 ) and systemic acidosis ( p less than 0.02 ) without altering cardiac index or total peripheral resistance .
C0027358
naloxone
C0036983
septic shock