during this treatment , however , rates of the early steps of the pathway were increased slightly ( 9-15 % ) in normal and hgprt-deficient strains , more markedly ( 32-60 % ) in cells with catalytically superactive pp-rib-p synthetases , and not at all in fibroblasts with purine nucleotide feedback-resistant pp-rib-p synthetases .
C0007634
cells
C0016030
fibroblasts