with nrk fibroblasts infected with a temperature-sensitive mutant ( la23 ) of rous sarcoma virus , cells grown at the nonpermissive temperature ( 39 degrees c ) showed the correspondence of the distributions of the microtubules and intermediate filaments characteristic of the normal phenotype but within 1 hr after a shift to the permissive temperature ( 33 degrees c ) there was an extensive retraction of the intermediate filaments around the cell nucleus whereas the microtubules remained dispersed into the cell periphery .
C0007634
cells
C0021770
intermediate filaments