with these two immunoassay systems and gel chromatography , we found beta-endorphin in all 20 c.s.f . samples tested at a concentration always higher than , but with no other relationship to , that in plasma . beta-endorphin was found in c.s.f . of patients who had hypopituitarism and undetectable plasma-beta-endorphin , suggesting that it is synthesized in the brain rather in the pituitary .
C0086045
concentration
C0006104
brain