in one approach , changes in plasma membrane ion flux were measured by flow cytometry , using a fluorescent dye indicator of membrane potential : cells briefly exposed ( 5-10 min ) to a dna-recombinant ifn-alpha 2 ( 100 to 800 u/ml ) manifested a consistent plasma membrane hyperpolarization ( -60 to -90 mv ) which could be blocked by ouabain .
C0007603
plasma membrane
C0007634
cells