electron microscopy confirmed the integrity of the sarcolemma of the cells exposed to high phenothiazine concentrations although metabolic alterations occurred in these cells as evidenced by an increased membrane permeability to the low molecular weight probe propidium iodide , degenerative changes in the fine structure of the mitochondria , the accumulation of autophagic vacuoles in the cytoplasm and the loss of contractile ability .
C0007634
cells
C0010834
cytoplasm