in a randomized study in vivo , we tested the following anti-free radical combination therapy administered at the beginning of cardiopulmonary resuscitation after apnea-induced cardiac arrest of 7 minutes : 1 ) ventilation with 100 % nitrogen for 30 seconds to allow the delivery of therapy before oxygen , 2 ) 10 mg/kg i.a . superoxide dismutase followed by 10 mg/kg i.v . over 1 hour to scavenge the superoxide anion radical , and 3 ) 20 mg/kg i.v . deferoxamine over 1 hour to prevent membrane lipid peroxidation .
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