in a patient with an initial serum theophylline concentration of 31.0 micrograms/ml and signs of toxicity ( arrhythmias and seizures ) , the administration of charcoal ( 4 doses of 30 g every 2 h ) reduced the half-life from 34.4 to 5.7 h concomitant with rapid resolution of signs of toxicity .
C0039771
theophylline
C0003811
arrhythmias