deletion of the cytoplasmic domain of cd2 did not alter binding of lfa-3 but eliminated the ability of cd2 to increase the response of the hybridoma to liposomes containing both hla-dr and lfa-3 , demonstrating that adhesion of lfa-3 to cd2 alone was insufficient for activation , and that the cytoplasmic domain was required for lfa-3 stimulation through the cd2 molecule .
C1367475
cd2
C0108773
cd2 molecule