'true recurrence ' should be defined as the return of the clinical and biochemical characteristics of cushing 's syndrome after a successful transsphenoidal operation , with a normal hypothalamic-pituitary-adrenal axis as evidenced by a normal response to dexamethasone , a normal diurnal rhythm of cortisol and a normal increase of plasma cortisol with insulin-induced hypoglycaemia .
C0010481
cushing 's syndrome
C0011777
dexamethasone