besides its putative role as a co-transmitter in dopaminergic neurotransmission [ hokfelt et al . 1980 ] , cholecystokinin is apparently involved in the central regulation of appetite and satiety [ gibbs et al . 1973 ; antin et al . 1975 ; parret and batt 1980 ; smith 1980 ; smith and gibbs 1981 ] furthermore , it has been shown that the brain concentration of the peptide is decreased in genetically obese mice as compared to non-obese animals [ strauss and yalow 1979 ] .
C0006104
brain
C0086045
concentration