since the oxygenated sterols that elevated the activity of fatty acyl-coa : cholesteryl acyl-transferase also suppressed the activity of 3-hydroxy-3-methylglutaryl coenzyme a reductase , the data suggest that the processes of cholesterol ester formation and cholesterol synthesis in human fibroblasts are regulated in a reciprocal manner by coordinate changes in the activities of these two membrane-bound enzymes .
C0001374
fatty
C0009226
coenzyme a