camostate feeding ( 200 mg/kg b.wt . orally twice a day ) resulted in a rapid elevation of odc activity already after 2 hours , reaching a maximum after 6 hours ( about 200fold above controls ) followed by a significant increase in putrescine after 4 hours and spermidine after 24 hours while spermine remained unchanged .
C0037871
24 hours
C0037874
spermine