we have compared the growth hormone release in normal volunteers and patients with various hypothalamo-pituitary disorders , following direct stimulation of the pituitary using 50 micrograms of the most potent homologue , hp grf 1-44 amide i.v . with that following indirect stimulation using oral clonidine 0.15 mg/m2 , which depends on intact hypothalamic mechanisms .
C0037668
grf 1-44
C0020663
hypothalamic