to determine the relationship between equilibrium binding of thrombin to sites on the platelet surface and the cleavage of membrane glycoprotein v ( gpv ) by thrombin , we examined the effect of active site-modified thrombin ( 1-chloro-3-tosylamido-7-amino-l-2-heptanone thrombin toslysch2-thrombin ) on the binding of native thrombin to platelets and on the hydrolysis of gpv by native thrombin .
C0025248
membrane glycoprotein
C0017968
gpv