in this report , we demonstrate that 1 ) il-1 production is a common property of murine t cell clones , 2 ) t cell il-1 activity is blocked by anti-il-1-alpha antiserum , 3 ) il-1-alpha mrna can be directly visualized in individual cloned t cells using in situ hybridization techniques , and 4 ) il-1 appears to serve an autocrine role in the activation of t cell clones inasmuch as anti-il-1-alpha antiserum blocks cell proliferation when the t cell is the only il-1 source .
C1155065
activation
C0039194
t cell