in the second study a progesterone-releasing iud ( 645 microgram per day ) inserted adjacent to the intact ovary at unilateral ovariectomy on day 14 inhibited early luteolysis in the subsequent estrous cycle and reduced the uterine secretion of pgf2alpha on day 5 , without affecting concentrations of progesterone in the peripheral circulation at the intervening estrus .
C0029939
ovary
C0041687
unilateral ovariectomy