here we report that macrophages activated in vivo by infection with bacillus calmette-guerin or in vitro by murine rifn-gamma or murine ifn-alpha/beta ( in the presence of the second signal lps in all cases ) develop inhibition of aconitase and the same two oxidoreductases of the mitochondrial electron transport chain as was documented earlier in target cells of cytotoxic activated macrophages .
C0024432
macrophages
C0015980
ifn