the herbicides amiprophosmethyl ( apm ) trifluralin , and oryzalin as well as the fungicides methylbenzimidazolyl carbamate ( mbc ) , o-isopropyl n-phenyl carbamate ( ipc ) , and chlorisopropyl n-phenyl carbamate ( cipc ) , which are known to cause the destruction of microtubules in vivo but do not interfere with tubulin polymerization in vitro , have been examined with respect to their ability to affect ca ( 2+ ) transport in isolated cell organelles .
C0026046
microtubules
C0041348
tubulin