in dogs with normal hearts , an infusion of nipradilol ( 10 micrograms/kg/min , i.v. , for 15 min ) decreased cpp by 25 % , cbf by 40 % , cardiac effort index by 45 % and mcf by 30 to 40 % , and it slightly increased lvedp without affecting myocardial high-energy phosphate and lactate levels .
C0018787
hearts
C0027061
myocardial