trimetoquinol , salbutamol and opc-2009 were about 18 , 570 and 2400 times less potent than isoprenaline.6 selectivity calculated from relative potencies indicate that opc-2009 was about 6000 times , salbutamol about 92 times and trimetoquinol about 8.2 times more selective than isoprenaline for tracheal smooth muscle as compared to ventricular muscle.7 the high potency and selectivity of opc-2009 for tracheal smooth muscle and its long duration of action suggest its potential usefulness for treatment of bronchial asthma.8 the present results are also compatible with the concept that beta ( 1 ) -adrenoceptors in cardiac muscle and beta ( 2 ) -adrenoceptors in tracheal and vascular smooth muscle can be distinguished .
C0001927
salbutamol
C0004096
bronchial asthma