to clarify the role of the breakdown of phosphatidylinositol 4,5-bisphosphate ( pip2 ) in gh secretion in human somatotrophs and the effects of inhibitors of gh secretion on this mechanism , we studied the effects of 12-tetradecanoylphorbol-13-acetate ( tpa ) and phospholipase c ( plase c ) on gh secretion and the interactions of somatostatin ( srih ) , bromocriptine , and pertussis toxin ( iap ) with tpa or plase c , using human gh-secreting pituitary adenoma cells in culture .
C1519424
somatotrophs
C0346302
gh-secreting pituitary