we have previously reported that the phorbol ester , 12-o-tetradecanoyl phorbol 13-acetate ( tpa ) induces , in the tt cell line of human medullary thyroid carcinoma , decreased cellular proliferation , increased calcitonin secretion , and enhanced calcitonin gene transcription ( debustros , a. , baylin , s. b. , berger , c. l. , roos , b. a. , leong , s. s. , and nelkin , b. d. ( 1985 ) j. biol . chem . 260 , 98-104 ) .
C0031586
phorbol ester
C0039654
12-o-tetradecanoyl phorbol