low doses ( 0.2-3 nmol ) of both [ d-ala2 , mephe4 , gly- ( ol ) 5 ] enkephalin ( dago , mu-agonist ) and [ d-ala2 , d-leu5 ] enkephalin ( dadl , delta-agonist ) caused dose-dependent increases in blood pressure and heart rate which were naloxone reversible .
C0525773
dago
C0014298
enkephalin