by introducing mouse g-csf chromosomal gene or its promoter dna into human carcinoma cell lines of chu-2 , sk-hep-1 , and u-87mg , it was shown that the constitutive expression of g-csf in these carcinoma cells was due to the intrinsic activation of nuclear factors which work on the promoter region of the g-csf gene .
C0008633
chromosomal
C0086860
dna