these noninvasive studies , when compared to the ones similarly conducted in the corresponding native nuclei , conclusively point to the artefactual nature of chromatin prepared by limited nuclease digestion , which has no resemblence with the in situ chromatin-dna structure being instead preserved by lysis of native nuclei and by subsequent sedimentation and suspension of the viscous chromatin mass .
C0008546
chromatin
C0007610
nuclei