the salient features of this method are ( 1 ) the on-line combination of distinct hplc retention mechanisms for enrichment and separation of the catecholamines to yield optimal assay specificity , ( 2 ) a lower working limit of detection of 25 pg norepinephrine and epinephrine per milliliter plasma based upon an assayed plasma volume of 1 ml , ( 3 ) the generation of calibration curves using standard additions to a 'like ' matrix , ( 4 ) a high daily sample throughput due to the lack of late-eluting chromatographic interferences and ( 5 ) use of an optimized aluminum oxide prepurification procedure .
C0007412
catecholamines
C0028351
norepinephrine