we conclude that in acute bacteremia , the early pulmonary hypertension is mediated largely by txa2 ( however , a second phase of hypertension results from non-cyclooxygenase products ) , either production of cyclooxygenase products ( perhaps pgi2 ) inhibits part of the action of pulmonary vasoconstrictors , or indomethacin stimulates the production of other vasoconstrictors ( such as lipoxygenase products ) , and indomethacin prevents the accumulation of evlw by blocking formation of cyclooxygenase products or by other nonspecific actions .
C0020542
pulmonary hypertension
C0033567
pgi2