when e. coli f+ cells carrying the dna-167 or dnac2 mutation , which causes the temperature-sensitive initiation of dna replication , are exposed to a non-permissive temperature to stop the replication of chromosome and f factor , and then transferred back to a permissive temperature with the addition of chloramphenicol , one round of the chromosomal replication occurs , but further replication is inhibited .
C0012854
dna
C0598312
replication