the optical resolution of the key intermediate , ( +/- ) -n- ( 7-guanidinoheptanoyl ) -alpha-alkoxyglycine ( vi ) was achieved by use of an exopeptidase , serine ( acid ) carboxypeptidase [ ec 3.4.16.1 ] and ( +/- ) -n- ( 7-guanidinoheptanoyl ) -alpha-alkoxyglycyl-l-amino acid ( viii ) as the substrate .
C0117059
exopeptidase
C0007075
carboxypeptidase