dexamethasone also raised the ratio of the acute proinsulin response to the acute immunoreactive insulin response in control subjects from 2 +/- 0.5 to 5 +/- 2 % ( p = 0.01 ) and in diabetic patients from 8 +/- 2 to 14 +/- 4 % ( p = ns ) , suggesting that the dexamethasone-induced increment in the basal ratio of proinsulin to immunoreactive insulin was also due to increased secretion .
C0033362
proinsulin
C0021641
insulin