in a double-blind placebo controlled crossover study we have compared the effect of oral pretreatment for 7 days with cgp ( 100 mg twice daily ) , with propranolol ( non-selective beta-adrenoceptor blocker with no isa ) and metoprolol ( selective beta-adrenoceptor blocker with no isa ) on resting heart rate and heart rate response to submaximal exercise on a bicycle ergometer to assess the degree of beta-adrenoceptor blockade and also the changes in blood pressure , heart rate and potassium during the intravenous infusion of ( - ) -adrenaline to determine the degree of beta 2-adrenoceptor blockade .
C0034783
adrenoceptor
C0001643
beta 2-adrenoceptor