in view of the reported effects of hydroxyurea on deoxyribonucleoside metabolism and possible relationship to control of dna replication ( bjursell , g. and reichard , p. ( 1973 ) j. biol . chem . 248,3904-3909 and walters , r.a. , tobey , r.a. and ratliff , r.l . ( 1973 ) biochim . biophys . acta 319 , 336-347 ) , we examined the fate of dna synthesized during and shortly after hydroxyurea treatment to determine if this dna exhibited any kinetic behavior which might be an indicator of aberrant synthesis .
C0598312
dna replication
C0012854
dna