pretreatment of mice with 125 mg kg-1 of diethyldithiocarbamate ( ddc ) several days before exposure to o2 resulted in 1 ) an increase in animal survival ( 92-100 % vs. 59 % o2 controls ) , 2 ) a reduction in pulmonary edema , 3 ) partial stabilization of thymus and spleen lymphocyte populations , and 4 ) restoration of the humoral response ( specific antibodies appeared earlier than in o2 control animals ) and improvement of the mitogenic proliferative response of the spleen cells after hyperoxia .
C0034063
pulmonary edema
C0030054
o2