furthermore , the diagnosis of partial enzyme deficiency could only be made with certainty by the acth stimulation test , because with sole measurement of basal levels ( 17-hydroxyprogesterone and 21-desoxycortisol in 21-hydroxylase deficiency , and 17-hydroxypregnenolone and dehydroepiandrosterone in 3 beta-hydroxysteroid dehydrogenase deficiency ) the enzyme defects are in most instances not revealed .
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