however , short-term injections of polyenic antibiotics have some effect on atpase activity on nuclear membranes : amphotericin b , considerably activates the enzyme . in vitro incubation of isolated dog kidney nuclei with amphotericin and nistatin at concentrations of 1 and 10 mcg/ml does not affect the activity of nuclear membrane atpase , while increased concentrations of polyenic antibiotics , ( up to 200 mcg/ml ) results in a slight inhibition of the enzyme activity .
C0007610
nuclei
C0028584
nuclear membrane