to examine whether an abnormal zinc status contributes significantly to the impaired in vivo cell-mediated immunity of the genetically diabetic c57bl/ksj db/db mouse , we measured specific cytotoxicity of spleen cells from db/db and heterozygous ( db/m ) and homozygous ( m/m ) control mice fed either zinc-deficient ( 2 mg/kg ) or zinc-adequate ( 20 mg/kg ) semipurified diets .
C0020966
cell-mediated immunity
C0301896
cytotoxicity