a high michaelis constant for pyruvate with a km = 6 . 10 ( -4 ) m and a somewhat weaker cooperativity as compared to the enzyme from e. coli reflect some minor differences , while the binding of the cofactor thiamine diphosphate ( km = 1 . 10 ( -6 ) m ) is identical for both enzyme complexes .
C0014442
enzyme
C0026741
enzyme complexes