the pattern of metabolites generated and the effects of the two types of cytochrome p-450 inhibitors suggests that the major isozyme of cytochrome p-450 that mediates the metabolism of benzo ( a ) pyrene within the spleen of untreated mice may be similar to the isozyme induced in the liver upon pretreatment with polycyclic aromatic hydrocarbons .
C0010762
cytochrome p-450
C0025519
metabolism