to investigate the role of four conserved aspartic acids at positions 71 , 99 , 105 , and 122 in muscarinic receptor function , point mutations in the rat m1 muscarinic receptor gene were made that converted each asp to asn , and wild type or mutant genes were stably expressed in chinese hamster ovary cells that normally lack muscarinic receptors .
C0531859
m1
C0034826
muscarinic receptors