as measured by octanol/water partitioning ( log p ) , the increase in lipophilicity of 8-substituted cyclic amp by esterification with a benzyl group was 7000-fold for 8-bromo-cyclic amp , 5000-fold for 8-methyl-thio-cyclic amp , and approximately 1000-fold for the other derivatives .
C0000661
8-bromo-cyclic amp
C0001455
cyclic amp