these findings suggest ( a ) that the synthesis of particular neuac-nle molecules is an important step for retinoic acid-induced granulocytic differentiation and this step could be bypassed or replaced by exogenous neuac-nlc , and ( b ) that the defective synthesis of particular neuac-nlc molecules is responsible for the failure of differentiation induction in retinoic acid-resistant hl-60 cells by retinoic acid .
C1516343
differentiation induction
C0040845
retinoic acid