while 6-azauridine displays a rather selective inhibitory effect , biological action of 5-azacytidine reflects the polyvalent inhibitory mechanism of the drug ( interaction with pyrimidine synthesis de novo , incorporation into rna and dna , depressed maturation of ribosomal rna , inhibition of rna and dna methylation , etc . ) and the analog displays pronounced cytostatic and immunosuppressive activity .
C0035701
ribosomal rna
C0035668
rna