by measuring the fluorescence intensities of the tryptophanyl residues and fad of the holoenzyme solution , and the fluorescence polarization of the holoenzyme solution containing halide anions such as iodide , bromide , chloride , or fluoride , we found that fad dissociates from the holoenzyme in the presence of iodide , bromide , or chloride , and the ability to dissociate fad from the holoenzyme decreases in order iodide , bromide , and chloride .
C0003075
anions
C0006222
bromide