the blocking effect of histones on accessibility of dna to dnase has been studied by addition of various histones to chromatin in intact or histone-depleted thymus nuclei ( those from which all lysine-rich histone was removed and those from which much of the arginine-rich histone was removed ) and to deoxyribonucleoprotein ( chromatin ) extracted from nuclei .
C0008546
chromatin
C0007610
nuclei