the ultrastructural organization of b-cell microtubular-microfilamentous system , its alteration by several pharmacological agents and the concomitant changes in the dynamics of insulin release , the biochemical characterization of islet tubulin and actin , the involvement of microtubules in the process of proinsulin biosynthesis and conversion , the analysis of motile events in endocrine pancreatic cells , the possible participation of microtubular-microfilamentous structures in cell surface organization of the b-cell , and the anomaly of the microtubular apparatus in certain pathological conditions are reviewed .
C0021641
insulin
C0033362
proinsulin