to investigate the latter suggestion and to examine the possible sites of hypothalamic peptidases inactivating lh-rh , d-ser ( tbu ) 6-ea10-lh-rh and d-leu6-ea10-lh-rh , which are known to have considerably greater activity than lh-rh , were incubated with a hypothalamic supernatant fraction containing active peptidases degrading lh-rh , and their gonadotrophin-releasing ability after incubation with the enzymes was tested in normal , adult male rats ;
C0020663
hypothalamic
C0023610
lh-rh