these results highlight two related but incompletely understood phenomena as follows : 1 ) a functionally truncated krebs cycle in cholesterol-rich tumor mitochondria , and 2 ) a mechanism for providing higher cytoplasmic levels of precursor metabolite intermediates which help sustain deregulated cholesterogenesis in hepatomas and other malignant neoplasms .
C0026237
mitochondria
C0010834
cytoplasmic