on propagation in cynomolgus kidney cultures the modified viruses reached titers of approximately 10 ( 7 ) tcd ( 50 ) per ml. , as measured by cytopathogenic activity on renal epithelial cells in vitro , yet produced no perceptible pathologic changes in the muscles , kidneys , testes , ovaries , heart , pancreas , adrenals , liver , or spleen of cynomolgus monkeys inoculated intramuscularly .
C0022646
kidneys
C0001625
adrenals