to investigate further the role of the hypothalamic luteinizing hormone releasing factor ( lrf ) pulse generator and the pituitary lrf receptor in the regulation of gonadotropin secretion and gonadal steroidogenesis in the ovine ( o ) fetus and neonatal lamb , we measured the increment ( the difference between the concentration of plasma lh at time 0 and peak lh ) in olh ( delta olh ) and ofsh ( delta ofsh ) responses to a potent lrf agonist , d-trp6pro9net-lrf ( lrf-a ) , after consecutive daily doses in 17 ovine fetuses ( six females , 11 males ) and in 15 neonatal lambs ( six females , nine males ) .
C0020663
hypothalamic
C0023610
lrf