the examination has revealed marked changes in the intima expressed in variable degree disorganization of the microrelief of the luminal surface of the vessels ( diminution in the height and disappearance of the folds , their inadequate orientation , formation of spherical protrusions and crater-like cavities ) and in transformations of the structural organization of the endothelium and subendothelial layer ( intensification of pinocytosis , impairment of the integrity of intercellular contacts , lipidosis of endothelial cells , subendothelial edema ) .
C0014257
endothelium
C0225336
endothelial