in pulmonary sarcoidosis , the marked expansion of cd4+ ( helper/inducer ) t cells in the alveolar structures of the lung is maintained by local il-2 release by activated cd4+ hla-dr+ t cells without concomitant expansion and activation of cd8+ ( suppressor/cytotoxic ) t cells , suggesting that sarcoid may be associated with a generalized abnormality of cd8+ t cells .
C0039215
cd4
C0019764
hla-dr