the first evidence suggesting that these two molecules are different is that the egfr , but not gp160 , is constitutively detectable in the a431 cell tissue culture supernatant , and that a pulse of these cells with epidermal growth factor ( under conditions which permit the internalization of the receptor-ligand complexes ) significantly reduces the expression of the egfr without noticeably affecting the level of gp160 on the cell surface .
C0007634
cells
C0699040
cell surface