the effect of varying the numbers ( 4 , 5 , 10 , 20 and 40 ) of weekly applications of dmba to the dorsal skin of intact and castrate male and female rats on the induction of basal and squamous celled epitheliomas and of sarcomas has been investigated.basal celled tumours originate mainly in hair follicles and squamous celled neoplasms in the interfollicular regions of the epidermis and differ in their progression to malignancy .
C0027651
neoplasms
C0006826
malignancy