it was concluded that propranolol effectively reduced bp , but diastolic bp reduction was most rapidly obtained at 320 and 640 mg daily , that the activity of the renin -aldosterone system was initially suppressed in all group , but for unknown reasons it increased towards the control level after seven to eleven weeks of therapy with 320 and 640 mg/day , and that the reduction in systolic bp increased with higher doses of propranolol and with increasing urinary propranolol excretion .
C0020649
reduced bp
C0033497
propranolol