therefore , cooling reduces alpha 1-adrenergic responsiveness in canine cutaneous veins , but in the case of full alpha 1-adrenergic agonists such as norepinephrine and phenylephrine the inhibitory effect of cooling is buffered by an alpha 1-adrenoceptor reserve .
C1373109
alpha 1-adrenergic agonists
C0031469
phenylephrine