1 the effects of gamma-aminobutyric acid ( gaba ) and related substances were examined in guinea-pig ileum longitudinal muscle.2 gaba at doses ranging from 10 ( -7 ) m to 3 x 10 ( -6 ) m elicited a relaxation while at higher doses ( 3 x 10 ( -6 ) m - 10 ( -4 ) m ) , as previously described , it caused a contraction followed by relaxation.3 gaba-induced relaxation was bicuculline-insensitive , was mimicked by ( - ) -baclofen but not by homotaurine and muscimol .
C0016904
gaba
C0004609
baclofen