evidence is presented that brain noradrenaline ( na ) neurons in the locus coeruleus ( lc ) and major parts of the sns respond by burst activation in concert to stressful stimuli implying novelty or fear . alpha-adrenoceptor agonists such as clonidine exert a powerful inhibitory action on both lc neurons and the sns , thereby reducing the impact of salient environmental events on the organism .
C0006104
brain
C0023951
lc