however , certain aspects of this theory remain unclear : ( 1 ) why does the addition of caffeine to damaged cells elevate the level of dna synthesis when it supposedly blocks post-replication repair10,14 , and ( 2 ) as pointed out by cleaver15 , why does caffeine continue to exert its synergistic lethal effects until completion of the s phase16 , 17 , even though the size of newly synthesized dna seems normal much earlier18-20 ?
C0598312
replication
C0012854
dna