the biologic activity in terms of survival of normal hematopoietic stem , osteosarcoma , and l1210 leukemia cells was determined for the following compounds : cyclophosphamide , its derivatives isophosphamide and trophosphamide , its possible metabolites nor-nitrogen mustard , hydroxylamine mustard , 4-ketocyclophosphamide , and and acrolein , and two substitutes for its primary active metabolite 4-hydroxycyclosphamide anhydro-dimer ( 4-hydroxy-cp-anhydro-dimer ) and 4-hydroperoxycyclophosphamide ( 4-hydroperoxy-cp ) .
C0010583
cyclophosphamide
C0020823
isophosphamide