in contrast , pretreatment of cref cells with mms prior to infection with a host-range mutant of ad5 ( h5hr1 ) which contains a single basepair deletion in the e1a-transforming region of ad5 and displays a cold-sensitive transformation phenotype , results in an mms dose-dependent increase in the absolute number of transformed foci in comparison with solvent-treated controls as well as an increase in transformation frequency when normalized for cell toxicity .
C0016030
cref cells
C0007634
cell