reverse mutation ( ames ) tests with salmonella typhimurium ta98 , ta100 and ta1537 , and chromosomal aberration tests in vitro with a chinese hamster fibroblast cell line ( chl ) , were carried out on fluorinated pyrimidine derivatives , such as 5-fluorouracil ( 5-fu ) , 1- ( 2-tetrahydrofuryl ) -5-fluorouracil ( ft ) , 5-fluorodeoxyuridine ( fudr ) , 1,3-bis ( 2-tetrahydrofuryl ) -5-fluorouracil ( fd-1 ) and a mixture of uracil and ft in the molar ratio 4 : 1 ( uft ) ( fujii et al. , 1978 ) .
C0016360
5-fluorouracil
C0041917
uracil