in 14 patients having congenital adrenal hyperplasia from a c21-hydroxylase enzyme deficiency , all of whom were receiving cortisol replacement therapy , the range in 17 alpha-hydroxyprogesterone concentrations observed in saliva ( 67-26,300 pmol/l ) was about 20-fold that seen in 32 healthy children ( 90-1520 pmol/l ) .
C0001627
congenital
C0020268
cortisol