characteristic cytologic features found in the four cases are summarized as follows : a ) distribution of cell 1 ) scattering , no tendency of grouping 2 ) moderate anisocytosis and anisokaryosis b ) cytoplasm 1 ) cyanophilic wispy cytoplasm 2 ) indistinct cytoplasmic rim 3 ) relatively clear cytoplasm 4 ) relatively low n/c ratio c ) melanin pigment 1 ) in melanoma cells-finely granular and diffusely packed in cytoplasm 2 ) in histiocytes-coarsely granular and densely packed in cytoplasm d ) nucleus 1 ) extremely eccentric nucleus 2 ) thin and irregular nuclear membrane 3 ) relatively regular chromatin distribution 4 ) finely or moderately granular chromatin pattern 5 ) prominent nucleolus 6 ) giant malignant cells ( 3-4 nuclei ) 7 ) intranuclear vacuole ( punched out ) .
C0007634
cell
C0007610
nuclei