four hypotheses are discussed : 1 ) the local factor was very important , with a zone of hyperactivity on the left circumflex artery , 2 ) one of the mechanisms of coronary artery spasm could be the nervous stimulation of this zone , 3 ) this zone was insensitive to nervous stimulation after autotransplantation but remained sensitive to methylergometrine , 4 ) the recurrence of resting angina and painful symptoms on stress testing suggests the possibility of reinnervation of the heart , as has been shown after cardiac transplantation , the autonomic nervous system does not play the role generally attributed to it in the genesis of spasm .
C0226037
left
C0018787
heart