three other agents ( n-formyl-methionine-leucine phenylalanine , bacterial lipopolysaccharide , and human csf alpha ) known to activate neutrophils did not compete directly for g-csf binding sites but , in preincubation experiments at 37 degrees c , were able to down-modulate the expression of g-csf receptors on human neutrophils in a dose- and time-dependent manner .
C0080090
g-csf receptors
C0086418
human