morphologically , the freshly isolated arthritic hepatocytes demonstrated the disappearance of the microvilli , the appearance of bleb-like protrusions in the plasma membrane and the widespread distribution of the rough endoplasmic reticulum associated with a relatively decreased area of the smooth endoplasmic reticulum in the cytoplasma .
C0230789
smooth endoplasmic reticulum
C0010834
cytoplasma