since the degraded myosin obtained after exposure to very small amounts of the rat proteinase is no longer able to respond to ca2+ , i.e . the functional activity of the molecule has been removed , the implications of a similar type of proteolysis operating in vivo are considered for myofibrillar protein turnover in general , but particularly with regard to the initiation of myosin degradation , which is known to take place outside the lysosome ( i.e . at neutral ph ) .
C0030946
proteinase
C0597304
proteolysis