the nuclear antiestrogen binding protein is not solubilized by 0.6 m potassium chloride , 2 m sodium chloride , 0.6 m sodium thiocyanate , 3 m urea , 20 mm pyridoxal phosphate , 1 % ( w/v ) digitonin or 2 % ( w/v ) sodium cholate but is extractable by sonication , indicating that it is tightly bound within the nucleus .
C0028589
nuclear
C0007610
nucleus