these findings indicate the close relationship between polymorphic mephenytoin 4'-hydroxylation and two stereospecific hexobarbital hydroxylations , and they suggest that p-450 human-2 is a typical s- ( + ) -mephenytoin 4'-hydroxylase and a major hexobarbital 3'-hydroxylase in the livers of extensive metabolizers .
C0608437
mephenytoin 4
C0023884
livers