the calcium antagonist dihydropyridine derivative nimodipine and its enantiomers bay n 5247 , bay n 5248 , as well as bay r 4407 ( calcium antagonist ( + ) -enantiomer of the calcium agonist dihydropyridine bay k 8644 ) do not exert antinociceptive effects in the rat as measured by the vocalization test in doses up to 100 micrograms/kg iv , and in the mouse as measured by the hot plate test in oral doses up to 100 mg/kg .
C0028094
nimodipine
C0012315
dihydropyridine