biosynthetic studies with [ 35s ] methionine labeling demonstrated that most of the cathepsin d remained intracellular and underwent proteolytic cleavage , converting a precursor of mr 47,000 d to a mature form of mr 39,000 d with processing intermediates of mr 43,000-41,000 d. greater than 90 % of the cathepsin d synthesized by oocytes bound to a mannose 6-phosphate ( man-6-p ) receptor affinity column , indicating the presence of phosphomannosyl residues .
C0597304
proteolytic
C0007427
cathepsin d