storage of red cells in acid-citrate-dextrose ( acd ) solution for more than a week has been shown to cause a reduction in red cell 2,3-diphosphoglycerate ( 2,3-dpg ) , resulting in a decrease in the half-saturation pressure ( p50 ) of stored blood , thus increasing hemoglobin-oxygen affinity and theoretically decreasing oxygen delivery to the tissues .
C0014792
red cell
C0019046
hemoglobin