control experiments revealed that under our experimental conditions , the inner mitochondrial membrane remained impermeable to small molecules , e.g. , sucrose , and that the release of aspartate aminotransferease , malate dehydrogenase , insocitrate dehydrogenase , and bulk protein into the intermembranal space in the presence of succinate occurred at a much lower concentration of digitonin than that required to disrupt the inner mitochondrial membrane .
C0024544
malate dehydrogenase
C0030016
dehydrogenase