very long chain fatty acids , which accumulate in plasma and tissues in x-linked adrenoleukodystrophy ( ald ) , neonatal ald , and the zellweger cerebrohepatorenal syndrome , are degraded by the peroxisomal beta-oxidation pathway , consisting of acyl-coa oxidase , the bifunctional enoyl-coa hydratase/3-hydroxyacyl-coa dehydrogenase , and beta-ketothiolase .
C0162309
ald
C0043459
zellweger