in voltage-clamp experiments on frog myelinated fibres it has been established that the increase in ca2+ concentration from 2 to 20 mm does not effect the use-dependent ( cumulative ) inhibition of sodium channels ( ina ) produced by the tertiary local anesthetics ( lidocaine , tetracaine , etidocaine ) and the quaternary antiarrhythmic drug n-propyl ajmaline ( npa ) .
C0023660
lidocaine
C0003195
antiarrhythmic drug