the actions of a closed-ring [ spironolactone , sc-9420 , beta- ( 7alpha-acetylthio-17beta-hydroxy-3-oxoandrost-4-en-17alpha-yl ) propionic acid lactone ] and of an open-ring [ sc-11480 , potassium beta- ( 17beta-hydroxy-3-oxoandrosta-1,4-dien-17alpha-yl ) propionate ] spirolactone have been examined on the cat perfused kidney , in concentrations ranging from 5 to 20 mg per 150 ml . of blood .
C0022947
lactone
C0037982
spirolactone