we also demonstrate a dramatic increase in the proportion of segregants occurring by gene inactivation in two of these hybrids as compared with those previously reported , indicating that this mechanism may be an important mode of phenotype segregation in diploid cells and , therefore , in the development of cancers -- such as the childhood tumors retinoblastoma and wilms tumor -- resulting from recessive alleles
C0006826
cancers
C0035335
retinoblastoma