the competitive nature of inhibition of rna polymerase by af/013 with respect to all four nucleoside triphosphate substrates , before and after enzyme-dna complex formation , as well as the competitive nature of inhibition of poly ( a ) polymerase with respect to atp tend to indicate that the major effect of af/013 on rna polymerase ii is at the level of the substrate binding as opposed to a specific inhibition of initiation .
C0035681
rna polymerase
C0035679
rna