furthermore , the effect of trh to reverse epinephrine-stimulated hyperglycemia appeared to be mediated by combined action of peripheral sympathetic and parasympathetic mechanisms to stimulate insulin release from the pancreas , since only complete blockade of the central autonomic outflow , but not selective perturbation of the sympathetic or parasympathetic outflow , or depletion of pancreatic insulin could substantially attenuate the antihyperglycemic action .
C0020456
hyperglycemia
C0021641
insulin