on analysis of molecular events associated with the ph1 chromosome , the leukemic cells of a patient with cml in mixed crisis showed bcr rearrangement and an 8.5-kb bcr-abl chimeric mrna , but those of a patient with ph1-positive hybrid acute leukemia showed no 8.5-kb bcr-abl mrna , as previously reported in a number of ph1-positive acute lymphoblastic leukemia ( all ) cases .
C1517806
leukemic cells
C0023464
hybrid acute leukemia