a three-state model of the benzodiazepine receptor is proposed in which benzodiazepine tranquilizers act as agonists enhancing the function of the benzodiazepine receptor as a coupling unit between gaba receptor and chloride channel , beta-carbolines act as `` '' inverse agonists '' '' reducing this coupling function , and ro 15-1788 represents a competitive antagonist blocking both the enhancing effect of agonists and the depressant effect of `` '' inverse agonists '' '' on gabaergic synaptic transmission .
C0034807
a
C0055363
chloride