1 the effects of vinblastine and 6-hydroxydopamine ( 6-ohda ) on various parameters of adrenergic neurone functions in the rat were examined and compared.2 during the first 12 h after injection of vinblastine , although the concentration of cardiac noradrenaline was unaltered , the turnover rate of the catecholamine in the heart was reduced to 40 ng g ( -1 ) h ( -1 ) compared to a rate of 66 ng g ( -1 ) h ( -1 ) in the hearts of animals treated with 0.9 % w/v nacl solution.3 the uptake of noradrenaline by rat atria in vitro was inhibited by vinblastine ( 2.5 x 10 ( -4 ) m ) or 6-ohda ( 5 x 10 ( -5 ) m ) , but only the inhibitory effect of vinblastine was readily reversible .
C0018787
hearts
C0018792
atria