although there are 8 orally active beta blockers currently approved in the u.s. for clinical use in systemic hypertension , only acebutolol possesses all of the salutary pharmacologic properties of cardioselectivity , intrinsic sympathomimetic activity and hydrophilicity , thereby making this compound an effective and safe beta-blocking agent for first-order management of a broad segment of the hypertensive population .
C0020538
systemic hypertension
C0000946
acebutolol