with both classical and immune interferons , the mean response of the trisomic cell lines was three times that of the normal cells , whereas that of the monosomic lines was half or less that of the normal cells , furthermore , a line trisomic for only the distal half of the long arm of chromosome 21 ( q21 leads to qter ) also demonstrated increased sensitivity to virus- and phytohemagglutinin-induced interferons , a fact that indicated that the gene responsible for the antiviral effect of interferon , avg , is located on this part of chromosome 21 .
C0021745
immune interferons
C0021747
interferon