the effects of topical cyclosporine were twofold : ( 1 ) cyclosporine increased tear production by 5 mm/min or greater in all cases of spontaneous kcs having an initial schirmer 's tear test value greater than 2 mm/min and in 59 % of eyes with an initial schirmer 's tear test value of 0 to 2 mm/min , and ( 2 ) cyclosporine caused marked regression of chronic corneal neovascularization and granulation even in eyes in which lacrimation failed to improve .
C0013238
kcs
C0015392
eyes