in dose and time schedule used in this study , it is inferred that estrogen and progesterone may exert their direct effect to hypothalamus on endogenous lh-rh secretion and also may exert their effect on pituitary gonadotrophs to change the sensitivity to lh-rh , i.e . these steroid hormones may be major factors in the control of gonadotropin release in the baboon .
C0020663
hypothalamus
C0023610
lh-rh