when isolated hela cell nuclei were digested in situ with micrococcal nuclease and the resultant chromatin was fractionated into nucleosome monomers ( v bodies ) and oligomers by sucrose gradient centrifugation , only material sedimenting faster than the 11s monomers was found to contain appreciable poly ( adp-ribose ) polymerase activity .
C0007610
cell nuclei
C0008546
chromatin