n-isopropyl-alpha- ( 2-methylhydrazino ) -p-toluamide hydrochloride ( procarbazine ; 50-1000 micrograms/ml ) induced dna damage in hepatocytes measured by an automated alkaline elution method , whereas no significant increase in unscheduled dna synthesis was seen .
C0012860
dna damage
C0012899
unscheduled dna synthesis