when captopril was injected intravenously in urethane anesthetized rats , a hypotensive effect accompanied by bradycardia was obtained , while an intravenous ( i.v . ) injection of prostaglandin i2 ( pgi2 ) , which induced hypotension of the same magnitude as the hypotensive effect obtained with captopril , caused a marked tachycardia .
C0020649
hypotension
C0006938
captopril