the mel 3 antibody was not nonspecifically reducing receptor binding to the arg-gly-asp sequence since , in binding assays with radiolabeled peptide performed with cells in suspension , very little peptide is bound by the melanoma cells under these conditions but addition of mel 3 , an antibody of igm isotype , causes a two- to threefold increase in specific binding .
C0020861
antibody
C0021017
isotype