using a hypothalamic slice preparation containing the suprachiasmatic nucleus ( scn ) and measurement of 2-deoxy [ 14c ] glucose ( 2-dg ) uptake by autoradiography , we have demonstrated that , after 1 h in vitro , 2-dg uptake into the scn is proportional to the rate of glucose utilization present in vivo at the corresponding subjective time of day and that , during an 8-h incubation in vitro , the scn is capable of spontaneously changing its metabolic rate .
C0020663
hypothalamic
C0038866
scn