the iv infusion of human beta-endorphin at a dose of 0.5 mg/h for 2 h in type-2 non-insulin-dependent diabetic patients ( n = 12 ) raised plasma insulin and glucagon levels and slightly but significantly lowered plasma glucose concentrations . beta-endorphin infusion also resulted in reappearance of a clear-cut acute insulin response to glucose , while second phase insulin release was increased and glucose disposal accelerated .
C0011860
non-insulin-dependent diabetic
C0021641
insulin