four hours after the topical administration of either aqueous methadone hydrochloride or sodium phenobarbital to hairless ( skh , hr-1/hr-1 ) mice , the mean drug concentration in liver was significantly lower in ethanol-treated mice than in control animals that had received only water ( methadone study , p less than 0.01 ; phenobarbital study , p less than 0.02 ) .
C0282303
sodium phenobarbital
C0031412
phenobarbital