it is shown that cholate extracts from cholera toxin-treated brush border membranes can efficiently reconstitute adenylyl cyclase activity in the guanine nucleotide-binding regulatory component ( gs ) -deficient cyc- variant of the s49 mouse lymphoma cell line ( cyc- cells lack the alpha subunit of gs needed to activate the catalytic subunit of adenylyl cyclase ) .
C0034987
regulatory component
C0007634
cells