of 21 patients with rheumatoid arthritis who began to receive low-dose weekly methotrexate up to five years ago , 15 ( 71 percent ) have continued to take this drug for a mean of 42 months and have received a mean total dose of 2,021 mg ( range : 915 to 3,075 ) .
C0003873
rheumatoid arthritis
C0025677
methotrexate