the rate constant beta ( h ( -1 ) ) for the second exponential decay of serum amylobarbitone concentration was reduced ( p < 0.01 ) , the urinary excretion of hydroxyamylobarbitone was reduced ( p < 0.001 ) and the mean serum water clearance ( c , ml/min ) representing amylobarbitone elimination by metabolism was reduced.5 .
C0221102
elimination
C0025519
metabolism