it is concluded that 1 ) although ureagenesis is ph dependent and also counteracts a tendency of amino acid oxidation to cause alkalosis , this tendency is inherently limited by the hyperammonemia ( delta n+ ) that necessarily accompanies it , 2 ) ammonium excretion is equivalent to hydrogen excretion in its effects on acid-base balance if , and only if , it occurs in exchange for sodium or is accompanied by chloride excretion and only when the glutamate generated by glutamine hydrolysis is oxidized .
C0002520
amino acid
C0017797
glutamine