while a decrease in cardiac beta-adrenoceptor function appears to be a general phenomenon in all kinds of heart failure , it is not always due to a selective reduction in cardiac beta 1-adrenoceptors : in mitral valve disease both cardiac beta 1- and beta 2-adrenoceptors decline concomitantly in relation to the degree of heart failure .
C0026265
mitral valve disease
C0018787
cardiac