antagonism of alpha 1-adrenoceptor-mediated vascular contraction by urapidil was examined in helical strips of femoral and mesenteric arteries isolated from 13-week-old aoki spontaneously hypertensive rats ( shr ) and age-matched normotensive wistar-kyoto ( wky ) rats , since this agent has antihypertensive effect through antagonizing peripheral alpha-adrenoceptors .
C0001638
alpha 1-adrenoceptor
C0034784
alpha-adrenoceptors