the failure of axonal regeneration in the transected spinal cord of mammals has been attributed to many factors , including an intrinsic lack of regenerative capacity of mature cns neurons , mechanical obstruction of axonal elongation by glial-connective tissue scars , necrosis of spinal tissue resulting in cavitation , lack of trophic influences sufficient to sustain outgrowth , and contact inhibition resulting from the formation of aberrant synapses .
C0027882
neurons
C0004461
axonal