in addition , the arginine-induced acute proinsulin response to total immunoreactive insulin response ratio was greater in diabetic patients ( n = 10 ) than in control subjects ( n = 9 ) ( 8 +/- 2 vs 2 +/- 0.5 % , p = 0.009 ) , suggesting that increased islet secretion per se accounted for the increased ratio of proinsulin to immunoreactive insulin .
C0033362
proinsulin
C0021641
insulin