increased in vitro tetraploidy occurred in skin cultures derived from all affected patients and some family members at risk studied in families with heritable colon cancer syndromes ( 15 of 16 gardner syndrome families , three oldfield syndrome families , and four families with heritable colon cancer syndrome without polyposis coli ) but was not present in all ( one gardner syndrome family , 16 of 19 familial polyposis coli families , and two turcot syndrome families ) .
C0039082
syndrome
C0027672
heritable