very similar ki values ( 0.2-0.3 microm ) were obtained for the - ( ch2 ) 3nh2 analog of amt when using folic acid , amt , mtx , and gamma-glutamyl-mtx as variable substrates , suggesting that the same enzymatic site on fpgs is active in the gamma-glutamylation of these four folyl derivatives .
C0016410
folic acid
C0025677
mtx