maintenance treatment with ipratropium bromide 40 micrograms three times daily reduced the provocative dose of histamine which caused a 20 % fall in fev1 ( geometric mean pd20 = 0.78 v 0.49 mg/ml , p less than 0.05 ) , despite an eight to 12 hour gap between the last dose of ipratropium and histamine challenge .
C0700580
ipratropium bromide
C0027235
ipratropium