the experiments demonstrated that : ( 1 ) kif are degraded by serine proteinases , ( 2 ) with prolonged incubation time intact kif are progressively replaced by more granular-amorphous material in transmission electron microscopy , ( 3 ) anti-kif autoantibodies bind to kif degradation proteins , ( 4 ) preincubation of kif with anti-kif autoantibodies does not exert any major protective effect for kif against proteolytic degradation , and ( 5 ) the enzymatic degradation products of kif can function as effective immunogens causing the formation of high-titer anti-kif antibodies .
C0010803
kif
C0021769
kif