when swine granulosa cells were cultured in chemically defined medium selectively deficient in ca2+ , the dose-dependent stimulation of ornithine decarboxylase ( ec 4.1.1.17 ) activity in response to prostaglandin e2 , l-epinephrine or the somatomedin , multiplication-stimulating activity , was attenuated markedly .
C0037657
somatomedin
C0021666
multiplication-stimulating activity