the inducible expression of the chimeric plasmid containing a 24-base-pair enhancer sequence of the p-450c gene placed in a heterologous promoter of sv40 was repressed by cotransfection with e1a dna , suggesting strongly that the inhibitory effect of the e1a proteins upon p-450c gene expression was caused by blocking the enhancer activity .
C1709313
e1a
C0101583
e1a proteins