substrate specificity experiments of the purified enzyme revealed that ( i ) the minimal length of a peptide chain required for n alpha-acetylation is 10 residues , ( ii ) the amino acids , ala , ser , met , and gly , which are predominantly found in the n termini of n alpha-acetylated proteins , are not the sole determinant of n alpha-acetylation for 10 and more residue peptides , and ( iii ) n alpha-acetyltransferase recognizes a minute difference in the side chain structure at the n termini of acth1-18-nh2 and [ gly1 ] acth1-18-nh2 , a productive and a nonproductive substrate , respectively .
C0001038
acetylation
C1261253
n