the role , if any , of these enzymes in promoting infection by pathogenic members of the genera neisseria , hemophilus , and streptococcus is not known , although the secretory immune system is primarily mediated by antibodies of the iga isotype , among which are iga1 subclass proteins , and these proteins are susceptible to cleavage by iga protease .
C0020835
antibodies
C0021017
isotype