after approsimate equimolar doses ( 3 mg/kg i.p . ) of methotrexate ( mtx ) methasquin ( mq ) , aminopterin , and n- ( [ 2,4-diamino-5-chloro-6-quinazolinyl ) methyl ] -amino ) benzol ) -l-glutamate ( 5-cl-deaza-am ) , total accumulation in small intestine was vie- to eight-fold greater than the dihydrofolate reductase content .
C0025677
methotrexate
C0002583
aminopterin