long-term controlled studies , ranging from 5 months to 3-1/2 years and using reliable , objective measures revela , however , that patients with rheumatoid arthritis improve in functional status and graduate to less severe classes of disease activity , a phenomenon not observed with either indomethacin or aspirin administered to matched patients over the same periods of time .
C0003873
rheumatoid arthritis
C0021246
indomethacin