to evaluate the efficiency of coupling between beta-receptor and adenylate cyclase catalyst via a gtp-binding protein , gs , in the brain membrane two parameters were employed : a beta-agonist-induced increase in the membrane gtp-dependent adenylate cyclase activity and a beta-agonist-induced shortening of the lag time preceding the onset of the steady-state activation by guanyl-5'-yl-beta-gamma-imidodiphosphate [ gpp ( nh ) p ] of the membrane cyclase .
C0018353
gtp
C0018366
gpp ( nh ) p