the binding of rna polymerase to dna significantly increases the formation of 1-methyl-adenine produced by methylation of the single-stranded dna region , diminishes by about 10 % the formation of 3-methyl-adenine by methylation within the minor groove and does not affect the formation of 7-methyl-guanine by methylation within the major dna groove .
C0012935
single-stranded dna
C0012854
dna