the synthetic peptides ( gly-arg-gly-asp [ grgd ] and gly-arg-gly-asp-ser-pro [ grgdsp ] ) containing the tripeptide arg-gly-asp ( rgd ) , originally found to be responsible for the cell binding activity of fn , have been found to inhibit ec spreading and the redistribution of their cytoskeleton , including the formation of stress fibers and the localization of vinculin either on fg or on fn .
C0007634
cell
C0010853
cytoskeleton