over the 6-month period of vitamin a administration , the number of layers of spinous cells decreased in 85 % of the participants , the loss of polarity of basal cells was reduced from 72.2 % to 22.2 % of chewers , subepidermal lymphocytic infiltration was greatly diminished from 66.7 % to 5.5 % of chewers , and nuclei with condensed chromatin disappeared from the epidermal layer ( 72.2 % before to 0 % at the end of the trial ) .
C0007610
nuclei
C0019397
condensed chromatin