we studied the effect of six class i antiarrhythmic drugs , i.e. , quinidine ( 5 micrograms/ml ) , disopyramide ( 10 micrograms/ml ) , procainamide ( 30 micrograms/ml ) , flecainide ( 4 micrograms/ml ) , lidocaine ( 4 micrograms/ml ) and mexiletine ( 4 micrograms/ml ) , on the durations of the basic action potential ( apdb ) at a cycle length of 500 ms and on the premature apd ( apdt ) elicited at progressively increasing diastolic intervals ( di ) in canine purkinje fibers .
C0003195
antiarrhythmic
C0033216
procainamide