the presently reported findings : that spaced electroconvulsive treatment increases the density of alpha-1 adrenoceptor in the spinal cord as well as in the cerebral cortex of the rat , that treatment with various classes of antidepressant drugs , including antidepressant neuroleptics , affects in a similar manner alpha-adrenoceptors , elevating within 2 weeks the density of alpha-1 , and depressing the density of alpha-2 subpopulation , and that prolonged imipramine treatment in investigated strains of rats does not depress the beta adrenoceptor density within 3 weeks , but only after 6-week-treatment such an effect is observed , are discussed together with our earlier results .
C0003289
antidepressant
C0020934
imipramine