daily treatment of rats with 2,4,7-triamino-6-phenylpteridine ( triamterene , dyrenium ) a potassium sparing diuretic , in daly doses of 1.5 mg , 3 mg and 4.5 mg/100 g body weight over the period of three weeks caused severe degenerative changes of renal cortical and medullary tubules resembling osmotic ( sucrose ) nephrosis .
C0040869
triamterene
C0700653
dyrenium