we have further examined the action of these agents on single k+ channels in rat pancreatic b-cells 1 ) tolbutamide and glyburide , two hypoglycemic sulfonylureas which decrease k+ ( atp ) channel activity in the cell-attached patch , affect the kinetics of k+ ( atp ) channel in a manner similar to glucose .
C0017628
glyburide
C0038766
sulfonylureas