in the presence of human and rat liver microsomes or eight purified cytochrome p-450 isozymes reconstituted with nadph-cytochrome p-450 reductase , this phenolic antioxidant is converted to the oxidoreduction-active metabolite , tert-butylquinone , that can stimulate the nadph oxidase activities of these preparations by 2- to 7-fold .
C0010762
cytochrome p-450
C0030012
oxidoreduction