the metabolism of n-nitrosopyrrolidine ( npyrr ) via alpha-hydroxylation is modified by pretreatments of the animals with compounds which affect the microsomal level of cytochrome p-450 and by addition , in vitro , of 2-diethylaminoethyl-2,2-diphenyl valerate hydrochloride ( skf 525-a ) , an inhibitor of cytochrome p-450 .
C0025519
metabolism
C0010762
cytochrome p-450