the destructive reaction was accompanied by increased formation of cytochrome p-420 , loss of microsomal heme content , and diminished catalytic activity of cytochrome p-450-dependent monooxygenases such as aryl hydrocarbon hydroxylase and 7-ethoxycoumarin o-deethylase .
C0003927
aryl hydrocarbon hydroxylase
C0000644
7-ethoxycoumarin o-deethylase