to study the extent to which histamine methylation accounts for the biosynthesis of histamine metabolites in brain , the effects of the histamine methyltransferase ( hmt ) inhibitor metoprine were determined on the whole brain levels of tele-methylhistamine ( t-mh ) , its oxidative metabolite tele-methylimidazoleacetic acid ( t-miaa ) , and brain hmt activity in albino rats .
C0025723
methylation
C0025831
methyltransferase