in the presence of 0.1-0.2 mm ca2+ , the 68-kda and 160-kda components , and to a lesser extent the 200-kda component , of the neurofilament triplet polypeptides were degraded by the cytosolic protease , whereas the cytoskeleton-bound protease needed two-fold higher concentration of ca2+ to degrade the neurofilaments .
C1383501
cytosolic
C0010853
cytoskeleton