in order to examine the cellular mechanisms by which estradiol ( e2 ) exerts its acute negative feedback upon luteinizing hormone ( lh ) secretion , a temporal correlation was made among serum lh concentrations , pituitary responsiveness to luteinizing hormone-releasing hormone ( lhrh ) , and the translocation of e2 to nuclear ( ner ) receptors of the pituitary ( pit ) , preoptic hypothalamic area ( poa ) , and the caudal hypothalamic area ( hyp ) .
C0023610
pituitary
C0020663
hypothalamic