radioligand receptor studies show that alpha-methylnoradrenaline differs from noradrenaline in being much more selective ( 70 times ) for the alpha 2 subclass of adrenoceptors than noradrenaline and it is likely that the antihypertensive action of methyldopa results from selective activation of alpha 2 adrenoceptors by alpha-methylnoradrenaline in the nucleus tractus solitarius and the anterior hypothalamus .
C0028351
noradrenaline
C0025805
alpha-methylnoradrenaline