previous studies from this laboratory showed that ( i ) vinyl carbamate ( vc ) was much more carcinogenic than ethyl carbamate ( ec ) and that both carbamates induced the same spectrum of tumors in mice and rats , ( ii ) adducts of [ 14c ] - or [ 3h ] 1 , n6-ethenoadenosine and [ 14c ] - or [ 3h ] 3 , n4-ethenocytidine e were formed in the hepatic rna of infant male b6c3f1 mice administered [ 1-14c ] ethyl or [ 1,2-3h ] ethyl ec and ( iii ) vc formed much more of the 1 , n6-ethenoadenosine ( epsilon ado ) adduct in the hepatic rna and the 7- ( 2-oxoethyl ) -guanine adduct in the hepatic dna of mice than did ec .
C0006948
carbamates
C0041964
ec