in vivo administration of the phospholipase a2 inhibitor dibromacetophenone , the anti-inflammatory steroid fluocinolone acetonide or the lipoxygenase inhibitor nordihydroguiaretic acid just prior to i.p . injection of phorbol-12-myristate-13-acetate ( pma , 100 ng ) into unmanipulated cd-1 female mice resulted in a dose-dependent decrease in the number of peritoneal exudate cells ( pec ) producing superoxide anion radical ( o2 ) as assessed by the reduction of nitroblue tetrazolium , i.e . the formation of formazan-positive pec .
C0021966
i
C0003075
anion