caldesmon , a major calmodulin- and actin-binding protein of smooth muscle ( sobue , k. , muramoto , y. , fujita , m. , and kakiuchi , s. ( 1981 ) proc . natl . acad . sci . u. s. a . 78 , 5652-5655 ) , has been obtained in highly purified form from chicken gizzard by a modification of a previously published procedure ( ngai , p. k. , carruthers , c. a. , and walsh , m. p. ( 1984 ) biochem . j . 218 , 863-870 ) and was found to cause a significant inhibition of both superprecipitation and actin-activated myosin mg2+-atpase activity in a system reconstituted from the purified contractile and regulatory proteins without influencing the phosphorylation state of myosin .
C0001271
actin
C0026820
contractile