dihydroorotate dehydrogenase is mitochondrial in mammals , but the isofunctional enzyme , dihydroorotate oxidase was found to be cytoplasmic , whereas orotate phosphoribosyltransferase and orotidine-5'-phosphate decarboxylase , which are cytoplasmic in mammals , were found to be particulate .
C0026237
mitochondrial
C0010834
cytoplasmic