since betamethasone and betamethasone 17-valerate penetrate rat skin in vivo at essentially the same rate , it is concluded that the latter compound is relatively resistant to hydrolysis during penetration , and that it binds to rat corticosteroid receptor proteins in such a manner as to prevent expression of corticosteroid activity .
C0005308
betamethasone
C0750848
betamethasone 17-valerate