to assess the potential of monoclonal antibodies that inhibit platelet function in vitro as in vivo therapeutic agents , f ( ab ' ) 2 fragments ( 0.17 to 0.81 mg/kg ) of a murine monoclonal antibody ( 7e3 ) that binds to platelet glycoproteins iib and/or iiia and blocks platelet aggregation induced by adp were infused into three dogs .
C1416485
platelet glycoproteins iib
C0032176
platelet aggregation