in the rat model of hypertension induced by a clip on the right renal artery , sparing the left kidney , we compared the efficacity and the endocrine , renal and cardiac effects of classical therapy ( ct ) of hypertension ( clonidine 0.2 mg/kg and dihydralazine 15 mg/kg in 2 daily subcutaneous injections and furosemide 30 mg/kg/day in the drinking water ) , with inhibition of the angiotensin converting enzyme with a new drug , the s-9490-3 ( 0.5 mg/kg in one daily administration ) .
C0020538
hypertension
C0016860
furosemide