we describe specific problems associated with the development of an aids vaccine i.e . lack of experience with human retroviruses , the integration of the hiv genome in cellular dna , hiv infection of critical cells in the immune system , persistence of hiv in the brain , large variations in the virus envelope gene , immune interactions with the cd-4 protein and the generation of infection enhancing antibodies .
C0019693
hiv infection
C0009450
infection