abnormal tubulofilamentous structures have been identified in electron micrographs of thin sections and negatively stained impression grids prepared from brains of animals with scrapie and other spongiform encephalopathies , and we showed that such tubules contain a core of filamentous structures resembling scrapie-associated fibrils ( saf ) .
C0036457
scrapie
C0162534
spongiform encephalopathies