a more variant mutant actin species is synthesized in hut-14t , which differs from the original mutant polypeptide by ( i ) one additional negative net charge , ( ii ) a short half-life in the cell , ( iii ) a greatly diminished ability to incorporate into the detergent-resistant cytoskeleton , ( iv ) a decrease in affinity for deoxyribonuclease i ( ec 3.1.21.1 ) , and ( v ) a faster rate of synthesis .
C0007634
cell
C0010853
cytoskeleton