three stages of clinical disease occurred in the principals : ( i ) an initial short ( 18.0 +/- 7.9 days ) stage of induction , during which the dogs usually grew suboptimally , but were otherwise healthy , ( ii ) an intermediate stage of preliminary clinical signs of deficiency , characterized by a variable period ( 58.5 +/- 37.0 days ) of progressive inappetance , failure to grow , loss of body weight , and coprophagia , and ( iii ) a terminal stage , which , in most dogs , was abrupt in onset and short ( 7.6 +/- 6.0 days ) and consisted of either a neurologic syndrome or sudden unexpected death syndrome .
C0012634
disease
C0039082
syndrome