the arrest of these mutants at the stage before meiosis i spindle formation could be attributed to the failure of dna synthesis because inhibition of synthesis by hydroxyurea also caused arrest at this stage. -- premeiotic dna synthesis occurred before the arrest of cdc7 , which is defective in the initiation of vegetative dna synthesis , and of cdc2 , which synthesizes vegetative dna but does so defectively .
C0598312
dna synthesis
C0012854
dna