we investigated the site of binding and the mechanism of aggregation of platelets by as-vwf by ( a ) pre-incubating platelets with either of two monoclonal antibodies , one against glycoprotein ib ( gpib ) or a second against the glycoprotein iib/iiia complex ( gpiib/iiia ) , and ( b ) varying the concentration of fibrinogen in the medium .
C0032176
aggregation
C0016011
glycoprotein iib/iiia