the positive chronotropic effect of acetone on acr can be reduced by adding 0.002 mm of propranolol ( a non-selective beta 1- and beta 2-adrenergic receptor blocker ) , or by pretreating the rat with reserpine ( an ne depleter ) ( 5 mg/kg body weight , i.p. , 24 h prior to experiment ) .
C1372804
positive chronotropic
C0028351
ne