human high molecular weight urokinase , a plasminogen activator , when minimally reduced with 0.01 m 2-mercaptoethanol for 10 h at ph 8.0 and 25 degrees c and then carboxymethylated with sodium iodoacetate , gave two chains , a functionally active heavy chain with about 80 % of the original activity and a light chain .
C0086418
human
C1420192
heavy chain