they received adriamycin , vincristine , prednisolone and l-asparaginase ( opal ) initially , and those in whom complete remission was achieved proceeded to cranial irradiation and intrathecal methotrexate , followed by continuous oral maintenance chemotherapy comprising weekly methotrexate , cyclophosphamide , and daily 6-mercaptopurine for 3 years .
C0042679
vincristine
C0084990
opal