the basis for our previous observations [ kaminsky , l.s. , guengerich , f.p. , dannan , g.a . & aust , s.d . ( 1983 ) arch . biochem . biophys . 225 , 398-404 ] that rates of microsomal metabolism of warfarin were markedly less than the sum of rates of the reconstituted constituent isozymes of cytochrome p-450 has been investigated .
C0025519
metabolism
C0010762
cytochrome p-450