parallel to these , hypertrophy of the golgi apparatus and rough endoplasmic reticulum , formation of giant mitochondria and presence of a great number of secretory cells in the cellular cytoplasm were noted in zona fasciculata spongiocytes and chromaffin cells of the adrenal medulla , and in beta cells of the pancreatic islets during aging thus evidencing for the adaptive changes in the ultrastructure of these cells .
C0230779
rough
C0007634
cells