the live oral vaccine gave significantly better protection than the heat-vaccinated , subcutaneously injected vaccine since ( i ) only control calves and calves given the killed vaccine developed profuse diarrhea , ( ii ) clinically , the mild fever responses seen after challenge in calves given the live vaccine were significantly lower ( p less than 0.0005 ) , ( iii ) autopsies performed 21 days after the challenge infection revealed normal findings in calves given the live vaccine , whereas calves given the killed vaccine showed signs of acute enteritis and chronic salmonellosis , ( iv ) all 12 calves given either 100 x or 100,000 x the ld25 survived the 21-day observation period ;
C0042210
vaccine
C0042212
killed