we suggest that the primary event in receptor-stimulated inositol phospholipid metabolism is phosphodiesterase attack upon ptdins4,5p2 to yield 1,2-diacylglycerol and inositol-1,4 , 5-trisphosphate , and that this is an essential coupling event in a general mechanism by which receptors mobilize ca2+ in the cytosol of stimulated cells .
C1383501
cytosol
C0007634
cells