the effect of liposomally-associated vitamin k1 , administered orally , was investigated using rabbits with warfarin-induced hypoprothrombinaemia , and evaluated in comparison with other dosage forms of the vitamin , including a vitamin k1 emulsion , the physical mixture of the emulsion with empty liposomes , polyoxyethylene hydrogenated castor oil ( hco-60 ) -stabilized emulsion and the vitamin solubilized by hco-60 .
C0220825
evaluated
C0031809
physical