endothelial cells from human umbilical veins produce a procoagulant identified as thromboplastin ( tissue factor , factor iii ) when stimulated with the phorbol ester 12-0-tetradecanoyl-phorbol-13-acetate ( tpa ) , phytohaemagglutinin ( pha ) or endotoxin , inducible thromboplastin synthesis ( i.e . synthesis of the protein component of thromboplastin , apoprotein iii ) was totally inhibited by cycloheximide and actinomycin d , indicating that de novo protein and rna syntheses are necessary .
C0003601
apoprotein
C0033684
protein