the positive relationship between cl1mu and cl3mx in both smokers and nonsmokers ( r = 0.98 , p less than 0.001 ) supports the concept that two n-demethylation pathways for theophylline metabolism are under common regulatory control and involve a form of cytochrome p450 distinct from that mediating 8-hydroxylation of theophylline to dmu .
C0025519
metabolism
C0010762
cytochrome p450