to determine whether a serum parameter of collagen metabolism , serum procollagen type iii peptide , correlated with hepatic collagen in a model of diet-induced fibrosis , rats were fed a control or cirrhogenic diet for 6 months and treated with either subcutaneous vehicle or the hepatoprotective prostaglandin 16,16-dimethyl prostaglandin e2 ( 100 micrograms per kg ) twice daily .
C0033554
prostaglandin
C0012472
prostaglandin e2