in vitro microsomal metabolism of the r and s enantiomers of warfarin to dehydrowarfarin and 4'- , 6- , 7- , 8- , and 10-hydroxywarfarin is catalyzed by cytochrome p-450 isozymes and was used as the basis for evaluating similarities and differences between human cytochrome p-450 isozyme compositions .
C0025519
metabolism
C0010762
cytochrome p-450