similar to the dna knotting reaction by bacteriophage t4-induced topoisomerase ( liu , l. f. , liu , c. c. , and alberts , b. m. ( 1980 ) cell 19 , 697-707 ) , the knotting reaction by the drosophila topoisomerase ii requires a high ratio of enzyme/dna .
C0012854
dna
C0000702
a