fibrin seal ( consisting of fibrinogen , cold insoluble globulin , factor xiii , antiplasmin , platelet growth factor , thrombin , and calcium chloride ) , cryoprecipitate , at avitene were applied to areas of pulmonary wedge resections in dogs and cynomologus monkeys in an attempt to stop bleeding and air leakage .
C0040018
thrombin
C0019080
bleeding