the possibility of a primary familial immunological abnormality as an aetiological factor in childhood leukaemia was suggested by binding some infections significantly more frequently reported in parents than in controls , but more strongly supported by the finding of a significantly ( p less than 0.02 ) increased prevalence of disorders associated with autoimmunity ( but not of other conditions such as peptic ulceration , infective hepatitis , tuberculosis or malignancy ) amongst members of all families compared to those of controls .
C3714514
infections
C0037088
finding