administered at doses of 100 to 1,000 micrograms per day according to the clinical status , octreotide resulted in a definite reduction , sometimes complete , of diarrhoea and flushes in about 60 % of the cases , and in a significant decrease of urinary output of 5 hydroxy-indol acetic acid from initial values , in 18 patients that could be tested before and during the initial phase of therapy ( - 37.6 +/- 7.9 % , p less than 0.02 ) .
C0028833
octreotide
C0011991
diarrhoea