the n-acetylated analog of grf was as potent and active as the parent peptide , and the identity of the amino acid in position 2 of ( n-ac-tyr1 ) -grf ( 1-29 ) -nh2 proved to be determining for enzyme activation , with d-phe2 and d-trp2 derivatives acting as partial agonists and the ( n-ac-tyr1 , d-arg2 ) analog being an efficient competitive antagonist of grf ( 1-29 ) -nh2 .
C2697525
analog
C0037668
grf