although the growth-enhancing effects of both il-4 and tnf-alpha on the cd3-dependent t-cell proliferation were noticeable regardless of when these cytokines were introduced in culture , the inhibitory effect of il-4 on the cd3-independent il-2-initiated t-cell activation was observed only if il-4 was added at the initiation but not later than 24 hr of `` '' t cells + il-2 '' '' cultures .
C1155046
t-cell
C0021756
il-