observations on the steroid and peptide concentrations and interactions in the microenvironment of the human ovarian follicle have led to an understanding of three important issues in reproductive biology : ( 1 ) how the oocyte-granulosa-cell complex matures , ( 2 ) how a single follicle is selected and prepared for ovulation and ( 3 ) how the events are synchronized so that an ovum ready for fertilization is extruded at ovulation .
C0018207
granulosa-cell
C0018120
follicle