to determine the role of tissue-type plasminogen activator ( t-pa ) and immediate percutaneous transluminal coronary angioplasty ( ptca ) in treating patients with evolving transmural myocardial infarction , 50 patients received t-pa ( 1.25 mg/kg iv over 3 hrs ) or placebo according to 3:1 double-blind randomization 3.8 +/- 1.1 hr after onset of symptoms .
C0027051
myocardial infarction
C0032143
t-pa