the high incidence ( 28 % ) of hypersensitivity reactions , the temporal relationship ( 4 hours ) between the arteriographic procedure ( utilizing iodine-containing contrast medium ) and the initial infusion of ril-2 ( while some of the contrast medium was still present ) , and the absence of such hypersensitivity reactions among patients receiving systemic ( intravenous ) ril-2 ( not requiring the use of concomitant iodine-containing contrast medium ) provide additional evidence that in the presence of a potentially immunogenic moiety , ril-2 , a potent stimulant of the human immune system , can produce an initial sensitization followed by subsequent anamnestic reaction upon reexposure of the patient to the immunogen ( even without the additional ril-2 ) .
C0086418
human
C0021756
ril-2