3-isobutyl-1-methylxanthine , a potent inhibitor of cgmp-phosphodiesterase activity , potentiated the differences in cgmp between slices of the hepatomas and surrounding liver or control , suggesting that the higher steady-state cgmp content of the tumors reflected enhanced basal cgmp synthesis which was partially offset by increased nucleotide degradation .
C2239176
hepatomas
C0023884
liver