our results suggest that : 1 ) manoalide modifies arachidonic acid release and metabolism to prostaglandins and leukotrienes in mouse cultured peritoneal macrophages stimulated by phorbol myristate acetate , calcium ionophore a23187 and zymosan and 2 ) the analgesic properties of manoalide seem to be partially correlated with reduced eicosanoid production in zymosan-stimulated mouse peritoneal exudates .
C0206190
peritoneal macrophages
C0031153
peritoneal