these results suggest that 1 ) the hyperglycemic response induced by clonidine and other alpha-2 adrenergic agonists is mediated by alpha-2 adrenergic receptors located within the central nervous system and 2 ) clonidine-induced hyperglycemia is effected , in part , by enhanced gluconeogenesis .
C1373110
alpha-2 adrenergic agonists
C0009014
clonidine