although interaction of il-2-toxin with il-2r+ t cells initially mimics the stimulatory effects of il-2 upon c-myc , interferon gamma , il-2r , and il-2 gene expression , the consequences of inhibition of protein synthesis mediated by the adp-ribosyltransferase activity of the toxin dominate after 7 hr and are indistinguishable from those effects mediated by cycloheximide .
C0021756
il-2
C0879590
il-2 gene