the paper points out the importance of the cytologic study of the cerebro-spinal fluid as a routine procedure in cases of leukemia , since it is well known that the therapeutic agents have difficulty in penetrating the blood-brain barrier and that foci of cns leukemic infiltration may represent points of reactivation points of reactivation of the disease even during the therapeutic remission .
C0005854
blood-brain barrier
C3714787
cns