histological methods demonstrated that the use of psychopharmacological drugs in schizophrenic patients does not remove the characteristic neuron pathology ( shrinkage , atrophy , lipofuscin dystrophy , cytolysis ) , but increases the metabolic processes in the intact nervous cells ( an increase in the volume and basophilia in the cytoplasma , an enlargement of nuclei and nucleoli ) and the glia activity ( an increase in the amount of perineuronal satellites , general glia and the glioneuronal index ) .
C0007610
nuclei
C0007609
nucleoli