oxotremorine increases plasma norepinephrine from 0.62 +/- 0.07 to 3.01 +/- 0.47 ng/ml and plasma epinephrine , from 0.82 +/- 0.14 to 3.42 +/- 0.48 ng/ml , in conscious unrestrained rats . l-propranolol ( 0.5-2.5 mg/kg ) reduces tremor , and at 2.5 mg/kg is more effective than either chemical sympathectomy or adrenal demedullation . d-propranolol and sotalol are also active at 4 and 10 times the dose of l-propranolol , respectively . l-propranolol does not prevent the rise in catecholamines induced by oxotremorine .
C0028351
norepinephrine
C0014563
epinephrine