light and electron microscopic studies of skin from patients with inherited connective tissue disorders ( e.g. , ehlers-danlos syndrome , osteogenesis imperfecta , marfan syndrome , cutis laxa ) have led us to the following generalizations about what components change , how individual collagen or elastic fibers are altered and how individual alterations affect overall dermal organization : 1 ) there is a limited change in the repertoire of collagen fibrils in the skin ;
C0410787
inherited connective
C0013720
ehlers-danlos syndrome