when controlled by the sv40 early promoter plus enhancer region ( svr11e1a ) this mutant e1a region is capable of immortalizing primary baby rat kidney ( brk ) cells , showing that the information essential for immortalization is located in the n-terminal part of region e1a and is shared by the 13 s and 12 s mrna gene products .
C0086222
enhancer
C0007634
cells