to determine whether the extent of estrogen deficiency influences the occurrence of the disturbance , the authors measured the levels of estradiol ( e2 ) , estrone ( e1 ) , and sex-hormone binding globulin ( shbg ) , and the percent and total non-shbg-bound e2 in 24 women with frequent hot flashes and 24 women who had never experienced the symptom .
C0014942
estrone
C0600142
hot flashes