when brain grafts containing gnrh cells were used to correct reproductive deficits in hypogonadal mice , there were higher splenocyte counts in males with grafts , a similar trend in females , and a lower ratio of single staining cd4+ to cd8+ thymocytes in all females with grafts vs. all females without , regardless of whether or not the grafts corrected the reproductive hormone status of the recipients , indicating an effect of the graft surgery on the immune system .
C0023610
gnrh
C0035150
reproductive