the deletion of the leu-13 residue in a mutant in which two glycine residues had previously been deleted from the hydrophobic region ( inouye , s. , vlasuk , g. , hsiung , h. , and inouye , m. ( 1984 ) j. biol . chem . 259 , 3729-3733 ) was found to cause the accumulation of the unmodified form of the protein in the cytoplasm and cytoplasmic membrane .
C0010834
cytoplasm
C0007603
cytoplasmic membrane