in a multicenter , single-blind , interpatient study , 103 outpatients with mild to moderate hypertension were given , after 2 weeks of placebo wash-out , 160 mg oxprenolol slow-release in fixed combination with chlorthalidone ( 20 mg per tablet ) ( sroc 160 ) once daily or conventional oxprenolol ( 80 mg ) in fixed combination with chlorthalidone ( 10 mg per tablet ) ( coc 80 ) twice daily for 8 weeks .
C0020538
hypertension
C0008294
chlorthalidone