using the earlier established liposome system for antigen presentation , in which liposomes bearing major histocompatibility complex ( mhc ) -class ii molecules inserted into and protein antigen covalently linked to the membrane were found to be sufficient for an antigen-specific and mhc-restricted activation of t cells , the minimal requirements for t-b cell interaction were investigated .
C0206431
antigen presentation
C0019630
major histocompatibility complex