all compounds showed receptor binding , and 1- ( n ) -fluoresceinyl naltrexone thiosemicarbazone displayed the highest mu-receptor affinity with a ki value of 3 nm . l- ( n ) -fluoresceinyl naloxone thiosemicarbazone was a morphine antagonist in vivo , approximately 6 % as potent as naloxone and naloxonazine in the mouse hot-plate test .
C0027360
naltrexone
C0027358
naloxone