in the in vivo study , etu orally administered as a single 30 or 45 mg/kg dose to rats on day 19 of pregnancy was found to induce necrosis of neuroblasts in the fetal cns after 18 and 24 hours of dosing and a high incidence of hydrocephalus in postnatal pups at both doses .
C3714787
cns
C0020255
hydrocephalus