infusion of nicotine to inhibit prostacyclin synthetase completely reversed the bradycardia induced by bradykinin in captopril-treated rabbits , an effect unrelated to ganglion blockade by nicotine since mecamylamine had no effect on the actions of bradykinin . beta-adrenoceptor blockade with nadolol did not modify the bradycardia caused by bradykinin in captopril-treated rabbits whereas atropine methylnitrate caused a marked reduction .
C0428977
bradycardia
C0128170
atropine methylnitrate