in four patients , whose hypertension was not controlled ( supine blood pressure greater than 150 -- 90 mmhg ) by addition of 5 mg/day of prazosin to previous treatment ( diuretics and beta-blockers ) , clonidine ( 150 -- 450 microgram/day ) led to control of hypertension in three cases .
C0009014
clonidine
C0020538
hypertension