these results demonstrate that 1 ) the antidepressant activity of quinupramine can not be attributed to inhibition of monoamine uptake , 2 ) unchanged quinupramine penetrates into the cns and affects some of the processes of neurotransmission and 3 ) the pharmacological activities of imipramine , when administered orally , may be attributed to desipramine , the metabolite formed .
C0003289
antidepressant
C0011685
desipramine