synergism between il-2 and lentinan was also observed in mice bearing spontaneous lung micrometastases : neither il-2 ( less than 5 x 10 ( 4 ) u/mouse ) nor lentinan ( less than 2.5 mg/kg ) alone had a therapeutic effect , but multiple injections of il-2 with a single injection of lentinan resulted in significant inhibition of spontaneous pulmonary metastases .
C0024109
lung
C0153676
pulmonary metastases