in seven human melanoma cell lines and one human fibroblast strain some correlation of resistance to cell killing was found with two bifunctional alkylating agents ( melphalan , chlorambucil ) and three monofunctional agents ( 4 ( 5 ) - ( 3,3-dimethyl-l-triazeno ) imidazole-5 ( 4 ) -carboxamide ( dtic ) , methylmethane sulphonate ( mms ) and n-methyl-n1-nitro-n-nitrosoguanidine ( mnng ) , but little cross-resistance was found between these two groups of agents or with cytosine arabinoside ( ara-c ) .
C0016030
fibroblast
C0007634
cell