thirty-six subjects ( healthy , severe angina pectoris , or acute myocardial infarction ) were studied 15 minutes either after the beta 1-selective beta-blocking drug metoprolol had been administered in total doses of 2 and 10 mg intravenously or after pindolol , a beta blocker with intrinsic sympathomimetic activity ( isa ) , in total doses of 0.2 and 1.0 mg intravenously had been given .
C0002962
angina pectoris
C0025859
metoprolol