to test the possibility that lyb3 , an isogenic b cell-triggering receptor lacking in xid-mutant mice , plays a direct role in the maturation of the immune response , the antibody profile in normal mice immunized eigher with antigen alone or in combination with anti-lyb3 receptor substantially elevated and accelerated the primary igg2a response , whereas it had little effect on the igg1 response .
C0301872
immune response
C0003320
antigen