at steady state , binding was inhibited by unlabeled igf-i , igf-ii , msa iii-2 , msa ii , insulin , and proinsulin , in order of potency , but not by high concentrations of epidermal growth factor and human growth hormone , chemically unrelated polypeptides 125i-labeled igf-i binding to patient 's cells was decreased by approximately 75 % , whereas binding of epidermal growth factor to its cell surface receptors was unaffected .
C0021641
insulin
C0033362
proinsulin