in each circumstance , lysosomal enzyme release was reduced by previous treatment of cells with pharmacological doses of drugs which disrupt microtubules ( e.g . 10 ( -3 ) -10 ( -5 ) m colchicine ) or with agents which affect accumulation of adenosine 3 ' 5'-monophosphate ( camp ) ( e.g . 10 ( -3 ) m cyclic nucleotides and 2.8 x 10 ( -4 ) -2.8 x 10 ( -6 ) m prostaglandin e ( pge ) and a ( pga ) compounds ) .
C0007634
cells
C0026046
microtubules