using wheat germ agglutinin-purified insulin receptor extracted from liver , no significant difference in insulin binding was identified in either model of obesity . beta-subunit autophosphorylation was significantly decreased in both obese models relative to that in controls ( 72 % in the obese zfr and 49 % in the overfed sprague-dawley model ) .
C0028754
obese
C1257763
overfed