given chronically , the first and second generation antidepressants imipramine and citalopram , and antidepressant neuroleptics levomepromazine and chlorprothixene , elevated moderately but significantly ( by 15-30 % ) the density of [ 3h ] naloxone binding sites in rat cerebral cortical membranes .
C0020934
imipramine
C0003289
antidepressant