melc have acquired a pattern of dna hypomethylation , nuclease sensitivity , and partially disrupted nucleosome configuration of the chromatin containing the transcriptionally inactive alpha 1 and beta maj globin domains , which distinguish them from the domains of nonerythroid transcribed genes , e.g . immunoglobulin or albumin , or ribosomal rna genes which are actively transcribed in uninduced cells .
C0008546
chromatin
C0007634
cells