the diminished tolerance to asa damage in vitro when compared with in vivo , and the inability of 16,16-dimethyl prostaglandin e2 to prevent these damaging effects in vitro , underscores the probable crucial role for blood flow , and possibly neural innervation , in mediating the protective effects of prostaglandins .
C0012472
prostaglandin e2
C0033554
prostaglandins