we conclude that a site capable of accelerating the plasminogen activation by tissue-type plasminogen activator preexists in fibrinogen , that this site becomes exposed upon fibrin formation or disruption of fibrinogen by plasmin or cnbr and that this site is within the stretch a alpha 148-197 , which is retained in the a alpha-chain remnants of fibrinogen degradation products .
C0015982
fibrin
C0163275
fibrinogen degradation products