the combination of antineoplastic agents used was changed from 5-fluorouracil ( 5-fu ) + vincristine ( vcr ) + bleomycin ( blm ) or peplomycin ( pep ) + mitomycin c ( mmc ) or 5-fu + vcr + pep + cyclophosphamide ( cpm ) + adriamycin ( adm ) to cpm + adm + cis-platinum ( ddp ) or methotrexate ( mtx ) + vinblastine ( vbl ) + adm + ddp .
C0042679
vincristine
C0280658
vcr