that proinsulin mrna content was a good indicator of diabetes severity and islet dysfunction was seen in the inverse correlation between proinsulin mrna content and fasting plasma glucose ( r = 0.69 , p less than 0.001 ) , and a direct correlation between proinsulin mrna and plasma insulin ( r = 0.86 , p less than 0.001 ) , and pancreatic insulin content ( r = 0.61 , p less than 0.01 ) .
C0033362
proinsulin
C0021641
insulin