to further elucidate the regulatory behavior of brain pdhc , the effects of 2-oxoglutarate and 3-hydroxybutyrate on the flux of pdhc ( as determined by [ 1-14c ] pyruvate decarboxylation ) and the activation ( phosphorylation ) state of pdhc were determined in isolated , non-synaptic cerebro-cortical mitochondria in the presence or absence of added adenine nucleotides ( adp or atp ) .
C0004927
behavior
C0006104
brain