caffeine 250 mg , raised blood pressure by 12/6 mm hg , from 129 +/- 25/78 +/- 12 ( mean +/- s.d . ) to a maximum of 141 +/- 30/84 +/- 16 mm hg at 45 minutes ( p less than 0.01 ) , but did not change heart rate , levels of norepinephrine , or epinephrine , or plasma renin activity .
C0028351
norepinephrine
C0014563
epinephrine