it is concluded that all three enzymes may be activated by increases in the intramitochondrial concentration of ca2+ and that the distribution of ca2+ across the mitochondrial inner membrane is determined , as in rat heart mitochondria , by the relative activities of a uniporter ( which transports ca2+ into mitochondria and is inhibited by mg2+ and ruthenium red ) and an antiporter ( which allows ca2+ to leave mitochondria in exchange for na+ and is inhibited by diltiazem ) .
C0230840
mitochondrial inner membrane
C0026237
mitochondria