we report here that this mutation was not found in 5 familial and 27 sporadic cases of creutzfeldt-jakob disease or in 3 patients with kuru , so that although this mutation may be responsible for amyloidogenesis and transmissibility in gerstmann-straussler-scheinker syndrome , it can not be the only cause of human spongiform encephalopathy .
C0022802
kuru
C0162534
spongiform encephalopathy