these results indicate that elimination of the regulatory domain of pkc produces constitutively active pkc that can bypass activation by the phorbol ester . delta pkc beta , in synergy with a calcium ionophore , was capable of activating the interleukin 2 promoter , indicating that cooperation of pkc-dependent and calcium-dependent pathways is necessary for activation of the interleukin 2 gene .
C0021756
interleukin 2
C0879590
interleukin 2 gene