in the virus-infected lymphocyte cultures of ebv-seropositive adult donors , in vitro regression of transformation , which is known to be caused by t lymphocytes , was suppressed by tpa , ebv-specific and -non-specific cytotoxicity of t cells generated in mixed cultures of peripheral blood lymphocytes ( pbl ) of seropositive adults and autologous lymphoblastoid cell line ( lcl ) cells was markedly lowered by the presence of tpa in the cultures , however , tpa had little effect on proliferation of t cells in stimulated cultures , and addition of tpa to the reaction mixture for the cytotoxicity test did not lower the cytotoxicity .
C0039194
t
C1155046
proliferation