to see whether antihistamines could prevent and reverse histamine-induced pulmonary edema and increased lung vascular permeability , we compared the effects of a 4-h intravenous infusion of 4 mug/kg per min histamine phosphate on pulmonary hemodynamics , lung lymph flow , lymph and plasma protein content , arterial blood gases , hematocrit , and lung water with the effects of an identical histamine infusion given during an infusion of diphenhydramine or metiamide on the same variables in unanesthetized sheep .
C0019588
histamine
C0062740
histamine phosphate