five pertinent topics are discussed : ( a ) examples of dominant , recessive , and x-linked single-gene disorders known to be associated with epilepsy , ( b ) examples of gross chromosomal aberrations associated with epilepsy , ( c ) discussion of multifactorial and polygenic inheritance and issues of genetic heterogeneity with specific reference to idiopathic generalized epilepsy , febrile seizures , and infantile spasms , ( d ) brief review of experimental clues to possible pathogenetic mechanisms underlying genetic forms of epilepsy , and ( e ) an overview of strategies for applying genetic linkage analysis to hereditary epileptic disorders .
C0037769
infantile spasms
C0014544
epileptic