1,4-dichloro-4-demethoxydaunorubicin and 2,3-dichloro-4-demethoxydaunorubicin were respectively as active and 2.5 times less active than was daunorubicin against hela cells in vitro while they were inactive against p388 and l1210 leukemias in vivo .
C0020789
4
C0011015
daunorubicin