opiate binding sites of the kappa-subtype were visualized in guinea-pig brain sections using in vitro autoradiography . kappa-binding sites , defined as [ 3h ] ( - ) -bremazocine binding in the presence of high concentrations of [ d-ala2 , mephe4 , gly-ol5 ] enkephalin and [ d-ala2 , d-leu5 ] enkephalin , were found in the cortical laminae v and vi , hippocampal dentate gyrus , and lateral habenulae .
C0006104
brain
C0086045
concentrations