studies we have done to identify the cellular substrate ( s ) of the lymphoma plasma membrane-associated pkc have shown that gp85 is preferentially phosphorylated in isolated membrane preparations following addition of the pkc activator , tpa ( phorbol-12-o-tetradecanoyl-phorbol 13-acetate ) , but not the biologically inactive tpa analogue , 4 alpha-pdd ( 4 alpha-phorbol 12,13-didecanoate ) .
C0007634
cellular
C0007603
plasma membrane