however , in a patient with known localized in situ carcinoma and previous persistent cytologic findings of the same from that particular site , the finding of frankly malignant cells from the same site in the follow-up bronchoscopic examination was almost definitely an indication of microinvasive carcinoma , which usually showed evidence of both in situ and invasive carcinoma in the bronchial brushing specimens .
C0334227
malignant cells
C1334274
invasive carcinoma