to determine the relative contributions of direct angiotensin-ii-like myotropism and sympathetic nerve stimulation to the partial agonist effect of saralasin , the renal vascular responses to i.v . saralasin ( 5 , 10 , 20 micrograms/kg/min ) were assessed in normal conscious rabbits before and after sympatholytic treatment with guanethidine ( 24 mg/kg/day for 9 days ) and in 6 chronic tetraplegic patients ( 0.5 , 1 , 5 micrograms/kg/min ) before and after alpha-adrenoreceptor blockade with i.v . thymoxamine ( 1 mg/kg/h ) .
C0003009
angiotensin-ii
C0036193
saralasin