although vancomycin had no effect on the presence or absence of documented fungal infection , patients treated with vancomycin received empiric amphotericin b for recurrent or persistent fever later ( mean of 14 days after initial antibiotic coverage was begun ) than did patients receiving placebo ( mean of 9.9 days ; p less than 0.005 ) , and thus received fewer total days of empiric amphotericin b therapy ( mean of 16.3 days ) than did patients given placebo ( mean of 24.6 days ; p less than 0.01 ) .
C0026946
fungal infection
C0002679
amphotericin b