to assess the mechanism by which inhibitors of angiotensin converting enzyme ( ace ) lower blood pressure , we evaluated the role of endogenous angiotensin ii in the antihypertensive effect of mk 421 , a long-lasting ace inhibitor , in rats made hypertensive by chronic infusion of norepinephrine or vasopressin .
C0020649
lower blood pressure
C0028351
norepinephrine