metabolism of 32-hydroxy-24,25-dihydrolanosterol ( lanost-8-ene-3 beta,32-diol ) , a posturated intermediate of the 14 alpha-demethylation ( removal of c-32 ) of 24,25-dihydrolanosterol ( lanost-8-en-3 beta-ol ) , by a reconstituted system consisting of yeast cytochrome p-450 which catalyzes lanosterol 14 alpha-demethylation ( cytochrome p-45014dm ) ( yoshida , y. , and aoyama , y . ( 1984 ) j. biol . chem . 259 , 1655-1660 and aoyama , y. , yoshida , y. , and sato , r. ( 1984 ) j. biol . chem . 259 , 1661-1666 ) and nadph-cytochrome p-450 reductase was studied .
C0025519
metabolism
C0010762
cytochrome p-450