resistance to the new fluoroquinolones ( e.g. , norfloxacin , enoxacin , ofloxacin , pefloxacin , and ciprofloxacin ) as a consequence of spontaneous single-step mutation occurs at a low frequency , less than 10 ( -9 ) , and generally results in a 300-fold lower level of resistance than does the mutation to nalidixic acid resistance .
C0949665
fluoroquinolones
C0008809
ciprofloxacin