our data indicate that ( 1 ) cns infection is very common in infants with systemic candidiasis , ( 2 ) combined flucytosine-amphotericin therapy may facilitate treatment of cns infection and should be the initial therapy for systemic candidiasis in infants , ( 3 ) gram stains of csf and urine enhance early diagnosis , ( 4 ) isolation of candida from normally sterile body fluids in high-risk infants should be considered pathogenic and therapy initiated unless the clinical course strongly suggests otherwise , and ( 5 ) toxicity from antifungal agents is common but usually reversible .
C0016278
flucytosine
C0006840
candidiasis