cypro administration caused a significant reduction in : 1 ) baseline 17-hydroxycorticosteroid ( 17-oh ) excretion ( -31 +/- 7.2 % ) , 2 ) the increase above baseline in 24 h 17-oh excretion on the day after metyrapone ( -32 +/- 4.9 % ) , 3 ) serum 11-deoxycortisol concentrations 8 h ( -45 +/- 5.5 % ) and 24 h ( -18 +/- 3.6 % ) after the first dose of metyrapone , and 4 ) plasma acth concentration 8 h ( -32 +/- 8.2 % ) and 24 h ( -22 +/- 8.0 % ) after the first dose of metyrapone .
C0000163
17-hydroxycorticosteroid
C0010139
11-deoxycortisol