we have found : ( 1 ) an early and transient deficit in taurine in weaver cerebellar cortex during the period of granule cell migration , ( 2 ) deficits during the second postnatal week in taurine , aspartic and glutamic acids in both weaver and staggerer cerebellar cortex , ( 3 ) that aspartic and glutamic acid deficits result from failure to increase concentrations at the normal rate after birth rather than from a fall from normal levels , ( 4 ) decreased concentrations of glutamic acid but not of taurine and aspartic acids apparent in the deep nuclei of both weaver and staggerer at about the same time as in cerebellar cortex , ( 5 ) amino acid changes in weaver heterozygote cerebellum which result in values intermediate in magnitude between normal and homozygous weaver animals and ( 6 ) an early and persistent reduction in staggerer deep nuclei of gamma-aminobutyric acid ( gaba ) , the purkinje cell transmitter , indicating early denervation or lack of full innervation of deep nuclei by purkinje cells .
C0007759
cerebellar cortex
C0007765
cerebellum