interleukin-1 ( il-1 ) , a cytokine , primarily produced by activated macrophages , has been involved in the control of hematopoiesis by acting synergistically with other hematopoietic growth factors , and has been demonstrated to be an effective agent in reducing the myelosuppression associated with the therapy for malignant disease .
C0018951
hematopoiesis
C0079490
hematopoietic growth factors