the analgesic effect of 5-hydroxytryptamine ( 5-ht , 200 and 250 micrograms/kg ) administered into the lumbar intrathecal space of rats was blocked in the tail-flick , hot-plate and shock titration tests of nociception when the animals had previously been treated with n-2-chloroethyl-n-ethyl-2-bromobenzylamine ( dsp4 ) , which depletes noradrenaline in the spinal cord .
C0036974
shock
C0028351
noradrenaline