selective destruction of central noradrenergic neurons by [ n- ( 2-chloroethyl ) -n-ethyl-2-bromobenzylamine ] ( dsp 4 ) or reserpine plus blockade of catecholamine synthesis by alpha-methyl-p-tyrosine abolished the hypotension and bradycardia produced by guanabenz but merely reduced the bradycardia from clonidine .
C0035179
reserpine
C0020649
hypotension