to investigate the actions of lidocaine and diltiazem on the ischemic alterations associated with the onset of acute ischemic arrhythmias , the left anterior descending coronary artery was occluded for 6-min periods separated by 30 min of reperfusion , under control conditions and after injection of lidocaine ( 2.4-3.8 micrograms/ml of plasma ) or diltiazem ( 390-510 ng/ml ) in open-chest anesthetized pigs .
C0023660
lidocaine
C0003811
arrhythmias