we have previously demonstrated in rat liver mitochondria a hydroperoxide-induced hydrolysis of pyridine nucleotides and release of ca2+ [ lotscher , h. r. , winterhalter , k. h. , carafoli , e. & richter , c. ( 1979 ) proc . natl acad . sci . usa 76 , 4340-4344 , and lotscher , h. r. , winterhalter , k. h. , carafoli , e. & richter , c. ( 1980 ) j. biol . chem . 255 , 9325-9330 ] .
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hydrolysis
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proc