premenopausal patients with progressive measurable metastatic breast cancer who demonstrated either stable or responsive disease 12 weeks following oophorectomy were randomized either to receive cyclophosphamide , methotrexate , and 5-fluorouracil ( cmf ) combination chemo-therapy ( 20 patients ) or to continue under observation alone ( 14 patients ) .
C0010583
cyclophosphamide
C0950521
cmf