those indicating a poor prognosis were : older age at onset , being underweight , poor grip strength , many affected joints , involvement of wrist or metatarsophalangeal joints , poor functional status , fulfilment of many of the american rheumatism association criteria for rheumatoid disease , raised erythrocyte sedimentation rate , seropositivity on sheep cell agglutination or latex tests , low haemoglobin level , raised blood urea level , and early erosions on x-ray films .
C0022417
joints
C0003873
rheumatoid disease