this observation indicates that the hypoprothrombinemia found in low birth weight infants at one day of age is attributable to reduced synthesis of factor ii coagulant antigen in the liver at this stage , but the prophylactic administration of vitamin k seemed to be effective even in such infants , probably because of the increase in factor ii coagulant antigen synthesis ( p less than .001 ) during the first seven days of life .
C0020640
hypoprothrombinemia
C0042878
vitamin k