in order to evaluate and compare the efficacy and safety of nifedipine retard and isosorbide-5-mononitrate as monotherapy in the treatment of stable angina , 18 patients with abnormal exercise electrocardiograms and angiographically proven coronary arterial disease were studied in a randomised placebo controlled double-blind crossover study comparing isosorbide 20 mg twice a day , sustained released isosorbide 40 mg once daily and nifedipine 20 mg twice a day each given for two weeks .
C0064079
isosorbide-5-mononitrate
C0022251
isosorbide