none of the sera from 50 normal individuals , seven patients with sjogren 's syndrome ( five of them primary and two associated with rheumatoid arthritis ; none of them with lymphoma ) , 25 patients with mixed connective tissue disease , 10 patients with systemic lupus erythematosus and five patients with progressive systemic sclerosis , had antibodies directed against this cytoplasmic specificity , as determined by indirect immunofluorescence .
C1527336
sjogren 's syndrome
C0003873
rheumatoid arthritis