release of lysosomal hydrolases ( including phospholipase a ) , increase in content of lysophosphatidyl choline and cardiolipin and decrease in content of phosphatidyl choline and phosphatidyl ethanolamine , activation of lipid peroxidation , inhibition of the cell antioxidant system , inhibition of tricarboxylic acid cycle enzymes and of beta-hydroxybutyrate dehydrogenase in mitochondria were detected in hepatocytes of rats after acute poisoning with necrosogenic toxins d-galactosamine , allyl alcohol and apamide .
C0007634
cell
C0026237
mitochondria