rats were given i.p . imipramine ( 20 mg/kg ) , acutely or chronically , and the levels of serotonin ( 5-ht ) , norepinephrine ( ne ) , dopamine ( da ) and their metabolites in the brain at different times were compared with the concentrations of imipramine and desipramine .
C0006104
brain
C0086045
concentrations