hgcl2 induced ( 1 ) a lymphoproliferation in spleen and lymph nodes involving b and t helper cells while the number of t suppressor/cytotoxic cells was not modified , ( 2 ) an increase in the number of ig containing cells resulting in a rise in all serum ig isotypes , and ( 3 ) an early thymic atrophy probably immunologically mediated , which was not involved in the induction phase of the disease since adult thymectomy had no effect .
C0040113
thymic
C0040071
thymectomy