previous studies demonstrating hydrolysis of phosphatidylinositol bisphosphate ( pip2 ) and generation of inositol phosphates in neutrophils exposed to 20.0 mm naf provide indirect evidence that activation of phospholipase-associated guanine nucleotide regulatory protein , a guanine nucleotide binding protein which regulates the activation of a membrane inositol-specific phospholipase c , is an early event in the neutrophil stimulus-response pathway triggered by fluoride .
C0037508
naf
C0016327
fluoride