in a short-term ( over 4 weeks ) clinico-microbiological study on 18 soviet school children , 12 years of age , it was found that a supervised oral hygiene action with the amine fluoride-containing caries-preventing agents silca and elmex fluid ( produced in the gdr ) had resulted in a marked reduction in plaque formation , an improvement in gingival conditions and a reduction of the germ content in the plaques .
C0016327
fluoride
C0011334
caries