its inhibition patterns with respect to substrate , glucose 1-phosphate , and activator , adenosine monophosphate , show it to be a potent ( ki = 40 microm ) r-state inhibitor of phosphorylase b , mimicking the binding of glucose-1-phosphate , and , as predicted for an r-state inhibitor , its binding to amp-activated phosphorylase a is even tighter ( ki = 10 microm ) .
C0031711
phosphorylase b
C0017916
phosphorylase