following partial blockade of the alkali-cation transport system with ouabain , two distinct but interrelated mechanisms operate in the cellular response : ( a ) an increase in intracellular na stimulates the pump so that the short-term alteration in electrolyte compostition is less than would be expected from the fraction of pump sites inhibited , and ( b ) there is a cycloheximide-sensitive recovery in transport capacity reflecting a restoration of functional transport sites to their normal density on the cell surface .
C0007634
cellular
C0699040
cell surface