a cell-mediated mutagenesis assay employing cultured primary sencar keratinocytes for the metabolism of promutagens , and v-79 fibroblasts as target cells for the resulting genotoxic metabolites , was used to survey the effects of murine beta-interferon ( ifn-beta ) on 7,12-dimethylbenz [ a ] anthracene ( dmba ) and benzo [ a ] pyrene ( bp ) -dependent mutagenesis and cytotoxicity .
C0016030
fibroblasts
C0015980
ifn-beta