following triple transfection of cos-1 cells with p450scc , adrenodoxin , and 17 alpha-hydroxylase cytochrome p450 plasmids , pregnenolone produced in mitochondria by the side-chain cleavage reaction can be further metabolized in the endoplasmic reticulum to 17 alpha-hydroxypregnenolone and dehydroepiandrosterone .
C0373704
pregnenolone
C0376260
17