the second selection , starting from one of the mutants obtained in the first-step selection , yielded a strain , gts-31 , in which both glucose uptake activity and the quantity of the glucose transporter were 10-20 % of the levels in cho-k1 cells , whereas the responsiveness of glucose transport to insulin , and the activities of leucine uptake and several glycolytic enzymes remained unchanged .
C0021641
insulin
C0017952
glycolytic