aphidicolin , a tetracyclic diterpenoid obtained from the culture filtrates of cephalosporium aphidicola and other fungi , inhibits the growth of eukaryotic cells and of certain animal viruses ( sv40 , herpes and vaccinia viruses ) by selectively inhibiting the cellular replicative dna polymerase alpha or the viral-induced dna polymerases .
C0007595
growth of
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cellular