in addition to being excreted in urine unchanged , tolazamide was metabolized to 1- ( hexahydroazepin-1-yl ) -3-p- ( carboxyphenyl ) sulfonylurea ( 2 ) , p-toluenesulfonamide ( 3 ) , 1- ( hexahydroazepin-1-yl ) -3-p- ( hydroxymethylphenyl ) sulfonylurea ( 4 ) , 1- ( 4-hydroxyhexahydroazepin-1-yl ) -3-p-tolylsulfonylurea ( 5 ) and a labile , unidentified metabolite 6 by man .
C0040372
tolazamide
C0038766
sulfonylurea