since reciprocal hyperreactivity ( day 1 ) and cross-tolerance to lethality ( day 4 ) could be achieved by treatment with salmonella smooth- or rough-form lps as well as with free lipid a , it was concluded that lipid a represents the active principle of lps in inducing both hyperreactivity and tolerance to the lethal effect of lps .
C0023767
lipid a
C0023810
lps