a specific , sensitive and reliable hplc method for the determination of doxorubicin ( dx ) , epirubicin ( epidx ) and their known fluorescent metabolites [ doxorubicinol ( dxol ) , epirubicinol ( epidxol ) 7-deoxy-adriamycinone ( metabolite c ) , adriamycinone ( metabolite d ) , 7-deoxy-13-dihydro-adriamycinone ( metabolite e ) , 13-dihydro-adriamycinone ( metabolite f ) , 4'-o-beta-d-glucuronyl-4'-epidx ( metabolite g ) and 4'-o-beta-d-glucuronly 13-dihydro-4'-epidx ( metabolite h ) ] in biological fluids ( human plasma , bile and urine ) has been developed and tested .
C0013089
doxorubicin
C0014582
epirubicin