the antitumor activity of 1- ( 2-chloroethyl ) -3-isobutyl-3- ( beta-maltosyl ) -1-nitrosourea ( ta-077 ) , a novel water-soluble nitrosourea derivative , against leukemia l1210 , ehrlich carcinoma , sarcoma 180 , lewis lung carcinoma , yoshida sarcoma , rat ascites hepatomas and walker 256 carcinosarcoma was examined and compared with those of 3 reference nitrosourea antitumor agents , 1- ( 2-chloroethyl ) -3- ( beta-d-glucopyranosyl ) -1-nitrosourea , 3- [ ( 4-amino-2-methyl-5-pyrimidinyl ) methyl ] -1- ( 2-chloroethyl ) -1-nitrosourea hydrochloride and 1- ( 2-chloroethyl ) -3-cyclohexyl-1-nitrosourea .
C0007097
carcinoma
C0243038
lewis lung carcinoma