as there is a continuous translocation of cytoplasmic receptor to the necleus in the growing uterus , the antagonistic action of antiestrogens appears to derive from their ability to effect a marked perturbation in the subcellular distribution of receptor , whereby very little of receptor ( ca . 10 % ) is cytoplasmic , and further estrogen receptor accumulation ( most likely synthesis ) is blocked .
C0010834
cytoplasmic
C0034804
estrogen