experiments using ( b10itimes c57bl/10 ) f1 responding lymphocytes sensitized and assayed with tnp-modified parental cells indicated that the homology required for lympholysis was between modified stimulating and modified target cellsmthe possibility is raised that histocompatibility antigens may serve in the autologous system as cell surface components which are modified by viruses or autoimmune complexes to form cell-bound modified-self antigens , which are particularly suited for cell-mediated immune reactions .
C0243092
cell
C0007634
cell