copper concentration , intracellular copper distribution , and inducibility of metallothionein-like metal-binding protein ( mlp ) by copper or cadmium addition to culture medium were compared among three types of skin fibroblasts derived from patients with menkes ' disease and wilson 's disease , both exhibiting genetic defects of copper metabolism , and from normal subjects ( control ) .
C0025545
metallothionein
C1323274
metal-binding