pulse-chase studies with 14c-glutamine as well as studies with various metabolic inhibitors of the ammoniagenic pathways suggest that glutamine in llc-pk1 cells is metabolized via mitochondrial pathway and that intramitochondrial phosphate-dependent glutaminase pathway plays a predominant role in the regulation of ammoniagenesis to acute acidosis .
C0026237
mitochondrial
C0017796
glutaminase