morphine concentration in the tissues assayed was plotted against the effect on gastrointestinal transit at the same interval for individual rats regardless of dose , administration route , and observation time : data analysis , in small intestine longitudinal muscle , but not in the brain or plasma , indicated a highly significant correlation and fitting of computer-generated curves described by a currently accepted equation according to the receptor occupation theory of drug response .
C0086045
concentration
C0006104
brain