by means of covalently immobilized fumarase and mitochondrial or cytoplasmic malate dehydrogenase we were able to detect physical interactions between different enzymes of the citric acid cycle ( fumarase with malate dehydrogenase , malate dehydrogenase with citrate synthase and fumarase with citrate synthase ) and between the enzymes of both mitochondrial and cytoplasmic halves of the aspartate-malate shuttle ( aspartate amino-transferase and malate dehydrogenase ) .
C0026237
mitochondrial
C0010834
cytoplasmic