in comparison with mean clearance estimates that have been reported for normal adult volunteers ( 0.293 +/- 0.078 liter/hr/kg ) , children less than 12 years of age ( 0.461 +/- 0.117 liter/hr/kg ) were found to have significantly higher clearances , whereas no difference was observed between older children ( 0.287 +/- 0.101 liter/hr/kg ) and adults .
C0008059
children
C1455726
older children