diagnosis of solid variants of endometrioid and serous carcinomas should also take into consideration the rate of occurrence of such ultrastructural signs typical of malignant cells as deep invaginations of the nuclear membrane , extended perinuclear space , increased number of nucleoli and macrosegregation of their content , increased number of myelin figures , polymorphism of mitochondria , cut-up cellular surface , well-developed laminar complex , and hypertrophy of the cytoplasmic reticulum .
C0230540
perinuclear space
C0007634
cellular