by using chimeric promoter constructions , in which distal and proximal segments of ctnt-129 are fused to reciprocal segments of the herpes simplex virus thymidine kinase ( hsv tk ) gene promoter , the dna segment responsible for this cell specificity can be localized to the ctnt distal promoter region , located between 50 and 129 nucleotides upstream of the transcription initiation site .
C0086860
constructions
C0007634
cell