in addition to the well-known features ( e.g. , intrauterine growth retardation , microcephaly , mental retardation and typical craniofacial abnormalities ) , 29 % of the cases had heart defects , 10 % had g.u . tract malformations , and 1.8 % had spina bifida .
C0025958
microcephaly
C0376634
craniofacial abnormalities