d-penicillamine , a reducing and chelating agent used in the treating of rheumatoid arthritis , was tested for its effects of polymorphonuclear leukocyte chemotaxis , phagocytosis , and lysosomal enzymes . beta-glucuronidase release from polymorphonuclear leukocytes after phagocytosis of latex particles was not affected by d-penicillamine at concentrations ranging from 25 to 400 mg/liter .
C0003873
rheumatoid arthritis
C0030817
penicillamine