two lines of evidence suggest that these genes may play a role in the development of human malignancy : ( 1 ) dna from a variety of human tumors transforms nih 3t3 mouse fibroblasts and the transforming genes from a number of carcinomas , sarcomas , and hematological malignancies have been identified as members of a family of genes , the ras family , closely related to the oncogenic genes of the harvey and kirsten murine sarcoma viruses ;
C0006826
malignancy
C1261473
sarcomas