as part of safety evaluation and drug development , 1,4-dihydroxy-5,8-bis [ [ 2- [ ( 2-hydroxyethyl ) amino ] -ethyl ] amino ] -9,10-anthracenedione dihydrochloride ( mitoxantrone , nsc 301739 , cl 232,315 , novantrone ) was tested in the mammalian test systems to determine its mutagenic potential .
C0003174
anthracenedione
C0026259
mitoxantrone