based on its location at the junction of the aortic isthmus and the ductus arteriosus , the continuity of the ductal wall with the fibromuscular curtain , and the association with cardiovascular malformations causing decreased blood flow through the ascending aorta , coarctation of the aorta is interpreted as the result of diminished blood flow through the fetal aorta , which leads to persistence and aggravation of the normally narrow isthmus and subsequent development of the curtain .
C0003956
ascending aorta
C0003483
aorta