at therapeutic free concentrations ( 120-360 nm in rheumatoid arthritis ) , the accumulation ratio for chloroquine ( 7-chloro-4- [ [ 4- ( diethylamino ) -1-methylbutyl ] amino ] -quinoline ; cq ) in viable isolated rat hepatocytes is 795 +/- 33 , which is of the same order of magnitude as in vivo hepatic uptake in the rat .
C0003873
rheumatoid arthritis
C0008269
chloroquine