the role of glutathione ( gsh ) as a determinant of cellular sensitivity to the cytotoxic and dna-damaging effects of cyclophosphamide ( cp ) was studied in a dual culture system of rat hepatocytes and k562 human chronic myeloid leukemia cells , which have elevated aldehyde dehydrogenase activity with a corresponding insensitivity to activated cp .
C0023473
chronic myeloid leukemia
C0010583
cp