we have directly compared neurite outgrowth from embryonic day 15 rat retinal explants placed onto beds of ( 1 ) schwann cells without ecm , ( 2 ) schwann cells expressing ecm ( including a basal lamina ) , ( 3 ) cell-free ecm prepared from neuron-schwann cell cultures , ( 4 ) nonglial cells ( fibroblasts ) , and ( 5 ) 2 isolated ecm components , laminin and type i collagen .
C0015350
cell
C0022984
laminin