the renal histology in the acute episode was that of scleroderma with intimal sclerosis and 'onion skinning ' of vessels and glomerular ischemic injury but with no evidence of damage by immune complexes either histologically or by immunofluorescence . improvement occurred after treatment with plasmapheresis , cyclophosphamide , and captopril with return of near normal renal function .
C0162864
intimal
C0005847
vessels