we studied the molecular mechanisms of the abnormal response of the beta-adrenergic receptor-adenylate cyclase system in the myocardium of spontaneously hypertensive rats ( shr ) by adp-ribosylation catalyzed by cholera toxin and pertussis toxin , by reconstitutive assay of cardiac membranes with the human platelet membranes , and by immunostaining with polyclonal antibody against beta gamma-subunits of guanine nucleotide-binding proteins .
C0001643
beta-adrenergic receptor
C0086418
human