multinucleated giant cell ( syncytium ) formation induced by the interaction between the gp120 glycoprotein expressed on the surface of cells infected with human immunodeficiency virus type ( hiv-1 ) and the cd4 receptor of uninfected cd4-positive ( cd4+ ) cells may play an important role in the depletion of t4 lymphocytes in acquired immune deficiency syndrome ( aids ) patients .
C0699040
surface of cells
C0007634
cells