in order to detect even subclinical hints of nephrotoxicity after application of carboplatin , sensitive non-invasive methods , e.g . determination of urinary enzyme ( lactate dehydrogenase , leucine aminopeptidase , gamma-glutamyltransferase , n-acetyl-beta-glucosaminidase ) , glomerular and tubular protein excretion ( albumin , alpha-1-microglobulin ) and determination of the creatinine clearance , were used .
C0033684
protein
C0001924
albumin