however , a number of newer fluoroquinolones ( at-4140 , opc-17100 , opc-17066 , pd-117596 , pd-124816 , pd-127391 , and win-57273 ) , all containing a cyclopropyl group at r-1 and , with the exception of win-57273 , either a halogen or methyl group at r-8 , were more active than ofloxacin in vitro .
C0949665
fluoroquinolones
C0028902
ofloxacin