in the light of these findings it is concluded that a dual regulation of single metabolic pathways , i.e . lipolysis , by a single class of hormones , e.g . catecholamines , ( 1 ) prevents excessive activation of lipolysis and cyclic amp accumulation which may lead to a depletion of cellular adenine nucleotides via an increased release of inosine and hypoxanthine which can not be re-utilized , and ( 2 ) adds a further degree of flexibility in regulation by restricting the stimulatory effects of both hormones to a narrow range of concentrations which is easily modified by inhibiting ligands .
C0001455
cyclic amp
C0001413
adenine nucleotides