upon incubation of antithrombin iii with thrombin in the presence of a monoclonal antibody recognizing an epitope exposed on the heavy chain part of thrombin-cleaved two-chain antithrombin iii , antithrombin iii was preferentially cleaved by the enzyme as a substrate , rather than covalently complexed with the enzyme to form an equimolar , stable acyl complex .
C0014442
enzyme
C0026741
complexed