the purpose of the present study was : ( 1 ) to determine the length of time required for the development of increased circulating insulin concentration and adipose tissue insulin resistance in response to gh in the ob/ob mouse , ( 2 ) to examine the relationship between the rise in insulin concentration and the development of insulin resistance , and ( 3 ) to test whether the hormone derivative could enhance insulin resistance in isolated adipose tissue when added in vitro .
C0020459
increased
C0021655
insulin resistance