from the biochemical data in the accompanying article and the morphological data here , we conclude that macrophages release cholesterol by two major pathways : 1 ) an hdl-independent secretion of lamellar bodies containing cholesterol , which originate from lysosomes , and 2 ) an hdl-dependent release of cholesterol via the formation of lamellar bodies descending from lipid droplets , which intracellularly fuse with hdl-containing endosomes .
C0008377
cholesterol
C0023822
hdl