using tryptophan , which facilitates the study of gluconeogenesis prior to the phosphoenolpyruvate ( pep ) carboxykinase step by increasing the level of certain hepatic metabolites , we have found that in animals fasted for 24 h glucose markedly decreased hepatic malate and aspartate concentrations without a corresponding fall in that of pyruvate , suggesting a decrease in pyruvate carboxylase activity .
C0017715
gluconeogenesis
C0017725
glucose