furthermore , a single intraperitoneal injection of 2,4-dinitrophenol ( dnp ; 30 mg/kg ) in ccl4-treated rats ( 1.0 ml/kg three times per week for 7 weeks ) showed hyperammonemia and hepatic encephalopathy ( loss of consciousness ) elicited a marked increase of tyr and phe levels in the brain .
C0019151
hepatic encephalopathy
C0006104
brain