in the other 13 patients the tpp effect was either normal or low , suggesting a deficiency or an inability to use the transketolase apoenzyme , probably as a result o long-standing thiamine deficiency or the presence of liver disease . a further eight patients ( 12.5 % ) had normal transketolase activity but a low tpp effect , perhaps reflecting failure of hte coenzyme tpp to recombine with the transketolase apoenzyme in the presence of normal thiamine stores .
C0009235
coenzyme
C0039848
tpp