after total mastectomy with axillary node sampling , followed by local radiotherapy , 1,032 pre- and perimenopausal women with operable breast cancer were randomized to observation alone , or to adjuvant chemotherapy for 1 year with either cyclophosphamide monotherapy or with a combination of cyclophosphamide , methotrexate , and 5-fluorouracil ( cmf ) .
C0016360
5-fluorouracil
C0950521
cmf