biogenesis of the mitochondrial matrix enzyme , ornithine transcarbamylase , has been shown to begin with synthesis on cytoplasmic ribosomes of a precursor , designated pre-ornithine transcarbamylase , which is approximately 4000 daltons larger than its corresponding mitochondrial subunit , followed by post-translational uptake and proteolytic processing of the precursor to its mature counterpart by mitochondria .
C0010834
cytoplasmic
C0035553
ribosomes