the hosts attempt to withhold iron from neoplastic cells by preventing the return of the metal to plasma and diverting it to storage , by increasing the synthesis of ferritin to accommodate the added stores , and by surrounding tumor cells with macrophages that can ingest lactoferrin-bound iron , but these mechanisms are often not effective against the iron-accumulating mechanisms of the tumor .
C0597032
neoplastic cells
C0027651
tumor