trichloroethylene ( tri ) , administered by gavage for 10 consecutive days , at doses of 500 to 1500 mg/kg body wt increased liver weight ( 175 % of control ) , decreased hepatic dna concentration ( 66 % of control ) , and increased the synthesis of dna ( 500 % of control ; as measured by [ 3h ] dt incorporation ) in b6c3f1 mice and alderley park mice .
C0012854
dna
C0598312
synthesis