the inhibitory substance : ( a ) was heat stable at 56 c for 30 minutes , ( b ) was not overcome by the addition of phytohemagglutinin , ( c ) was active in a manner that was proportional to the concentration of serum in the culture media , ( d ) was not lymphocytotoxic at a concentration which was profoundly inhibitory to blastogenesis , ( e ) was found in the first peak eluted from a sephadex g-200 column , ( f ) was nonspecifically active because it inhibited the blastogenesis of a panel of lymphocytes from healthy animals , ( g ) was present in 59 % of cows with lymphoma in the terminal stages of disease , ( h ) was rarely present in healthy cows or cows with inflammatory conditions , and ( i ) was not associated with bovine leukemia virus infection in the absence of tumor development .
C0024264
lymphocytes
C0024299
lymphoma