spermidine ( spd ) and spermine ( spm ) produced in anaesthetized dogs significant cardiovascular changes at higher doses than other transmitters , i.e . l-noradrenaline , l-adrenaline , histamine , acetylcholine , which produce cardiovascular effects at doses of 0.01-0.05 micrograms/kg given intravenously .
C0028351
noradrenaline
C0014563
adrenaline