within four hours of the onset of acute myocardial infarction 57 consecutive patients were randomised blindly to infusion of 150 mg recombinant tissue plasminogen activator ( rt-pa ) ( group 1 ) over five hours or placebo ( group 2 ) when they were first seen outside hospital or in the accident and emergency department .
C0027051
myocardial infarction
C0032143
recombinant tissue