when a fourfold or greater increase in tetanus antitoxin titre was obtained in 75 % of controls , the respective figures were 38 % in the sulphamethoxazole-trimethoprim-treated group ( p less than 0.05 ) , 45 % in the trimethoprim group ( p greater than 0.05 ) , and 50 % in the sulphamethoxazole group ( p greater than 0.05 ) .
C0041044
sulphamethoxazole-trimethoprim
C0041041
trimethoprim