the effects of chelation of divalent cations in the interaction of platelets and tumor cells has been studied in a homologous human system using human platelet-rich plasma and two tumor cell lines of human origin : sknmc ( neuroblastoma ) cells , which cause platelet aggregation by an adenosine diphosphate-dependent mechanism , and u87mg ( glioblastoma ) cells , which function by a thrombin-dependent mechanism .
C0032176
platelet aggregation
C0007634
cells