the role played by renal prostaglandin e2 in the maintenance of hypertension in chronic renal disease has been investigated through studying the response of body weight , blood pressure , glomerular filtration rate ( gfr ) , 24-hour natriuresis , plasma renin activity ( pra ) , plasma aldosterone and urinary pge2 excretion to the administration of indomethacin ( 2mg/kg daily , during 3 days ) .
C0022646
renal
C0022661
chronic renal disease