changes in the anions ( chloride , iodide , bromide , nitrate , bicarbonate , sulphate , phosphate , citrate , and acetate ) indicated that the molecular size of the anion rather than its chemical nature was the significant factor and suggested that the ions had to cross a barrier relatively impermeable to anions of radius greater than 3.5 to 4 a degrees . changes in osmolality and glucose concentration were without effect .
C0006222
bromide
C0003075
anions