these data demonstrate that ( 1 ) glycogenolysis is more sensitive than gluconeogenesis to the inhibitory effect of small increments in insulin concentrations , ( 2 ) gluconeogenesis could be suppressed by insulin but only at higher insulin concentrations , ( 3 ) this suppression of gluconeogenesis from alanine by insulin was due to an intrahepatic effect rather than an effect on the splanchnic extraction of alanine , and finally , ( 4 ) that insulin can suppress glucagon in the absence of hyperglycemia .
C0021641
insulin
C0020456
hyperglycemia