after the phagocytosis of parasites , macrophages were transferred into uninfected syngeneic mice , where they mimicked some of the important immunological changes normally associated with active trypanosome infection : ( i ) splenic background plaque-forming cells increased nonspecifically and ( ii ) the specific immune response to sheep erythrocytes was either enhanced or suppressed , depending on the timing of the antigen challenge : priming simultaneously with the transfer of trypanosome-containing macrophages enhanced immune responsiveness ;
C0031308
phagocytosis
C0007634
cells