when , on the other hand , the purified chalone was injected into rats following partial hepatectomy , not only was an inhibition observed during the g ( 1 ) -s transition but an increase in the ratio of metaphases to anaphases was found , suggesting that a block also occurs at metaphase as a result of the action of the purified liver chalone used in this study .
C0193398
partial hepatectomy
C0023884
liver