acceptability and plasma concentrations of rilmenidine , a new antihypertensive agent mainly eliminated via the kidney , were evaluated in 17 hypertensive patients ( supine diastolic blood pressure , 104 +/- 3 mmhg ) with renal insufficiency ( creatinine clearance , 35 +/- 4 ml.minute-1/1.73 m2 ; range , 12 to 58 ) .
C0022646
kidney
C0035078
renal