to discover if these alterations are linked to a genetic defect of the v1 receptor , we have studied the binding of vp on liver and kidney membranes of two other models , female diabetic mice c57 bl-6 orl db/db ( db/db mice ) and female zucker rats fatty/orl fa/fa ( fa/fa rats ) , which exhibit different temporal pattern of obesity , hyperinsulinemia and insulin resistance .
C0020459
hyperinsulinemia
C0021655
insulin resistance