these data indicate that ( 1 ) quantitatively , oc cells are the predominant cell type in the metabolism of lead in this in vitro system of oc and ob cell monolayers , ( 2 ) mediated incorporation of lead into oc cells occurs and likely involves changes in membrane permeability effected by hormonal stimuli , such as pth , and ( 3 ) modulations in cellular calcium metabolism induced by lead at low concentration may have the potential of disturbing multiple cell functions of different tissues that depend upon calcium as a second messenger .
C0007634
cells
C0007613
the