the changes in estradiol concentration were associated with decreases in ovarian weight ( 372 +/- 19 vs 185 +/- 11 mg , p less than 0.001 ) and in the microsomal enzyme activities of 3 beta-hydroxysteroid dehydrogenase ( 156 +/- 5 vs 53 +/- 4 nmol/mg prot/min , p less than 0.001 ) , 17 hydroxylase ( 4.7 +/- 0.8 vs 3.7 +/- 0.7 nmol/mg prot/min , p less than 0.002 ) , 17,20 desmolase ( 279 +/- 14 vs 50 +/- 7 pmol/mg prot/min , p less than 0.001 ) , 17 keto-steroid reductase ( 132 +/- 11 vs 6 +/- 1 nmol/mg prot/min , p less than 0.001 ) , and aromatase ( 19 +/- 1.5 vs 0.9 +/- 0.1 nmol/mg prot/min , p less than 0.001 ) in lhrha treated animals .
C0030016
reductase
C0003805
aromatase