compared with placebo , nicardipine significantly reduced mean blood pressure ( -14 % ) and renovascular resistance ( -28 % ) , increased heart rate ( +15 % ) , renal plasma flow ( rpf ; +21 % ) , glomerular filtration rate ( gfr ; +43 % ) and urinary sodium excretion ( +181 % ) .
C0028005
nicardipine
C0020649
reduced