we thus studied the possibility of coupling to proton transport by studying the following : 1 ) the effect of acidifying the epithelium by means of co2 and protonophores , 2 ) the effect of alkalinizing the epithelium with the anion-exchange inhibitor 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid ( dids ) and by removal of chloride from the serosal medium , 3 ) the effect of inhibiting the proton-translocating atpase of the skin , 4 ) dependence on mucosal ph .
C0003075
anion
C0008203
chloride