the h-35 rat hepatoma , a cell line which is relatively resistant to the classical anthracycline antibiotics such as adriamycin [ the concentration of drug which inhibits cell proliferation by 5090 ( ic50 ) = 2.5 microm ] and daunorubicin ( ic50 of 0.5 microm ) , is markedly more sensitive to the 4-demethoxydaunorubicin derivative , idarubicin ( ic50 of 0.025 microm ) .
C0011015
daunorubicin
C0020789
idarubicin