analysis of the distribution of cells along phases of the cell cycle uncovered in the high glucose cultures a decreased proportion of cells in g0-g1 ( 70.5 +/- 5 % versus 73.2 +/- 4 % in controls , p less than 0.05 ) and an increased proportion of cells in s phase ( 16.5 +/- 2.7 % versus 13.5 +/- 2.2 % in controls , p less than 0.01 ) , suggesting that the replicative delay is likely to occur between the phase of dna synthesis and mitosis .
C1516337
phases
C0007634
cells