in contrast to individuals with either hemolytic anemia without hemoglobinopathy or sickle cell anemia who had beta mrna to alpha mrna ratios of approximately one , a patient with hb s-beta-thalassemia had a ratio of beta mrna to alpha mrna of 0.75 while two subjects with homozygous beta-thalassemia had severe deficiencies of beta mrna .
C0019045
hemoglobinopathy
C0002895
sickle cell anemia