we now determine the in situ activity of this enzyme from the turnover of the deoxycytidine triphosphate ( dctp ) pool in rapidly growing 3t6 mouse fibroblasts , as well as in cells whose dna replication was inhibited by aphidicolin or amethopterin , by following under steady state conditions the path of isotope from [ 5-3h ] cytidine into nucleotides , dna , and deoxynucleosides excreted into the medium .
C0598312
dna replication
C0012854
dna