the close association of certain populations of anti-polynucleotide antibodies during the course of active sle , the presence of cross-reacting antigenic determinants of sdna , ndna , and dsrna , the preferential avidity of anti-ndna antibodies for sdna , and the frequent increase of anti-sdna antibodies in sle and other diseases associated with active tissue destruction suggest that sdna is a ubiquitous antigen that may stimulate the formation of antibodies reactive with a variety of polynucleotides .
C0003316
antigenic
C0003320
antigen