factor ixa active site-inhibited by 5-dimethylaminonaphthalene-1-sulfonyl glutamyl-glycylarginyl chloromethyl ketone was shown to be a competitive inhibitor of factor ixa binding in the absence ( ki = 2.3 nm ) and presence ( ki = 0.43 nm ) of factor viiia and factor x and of factor x activation ( ki = 0.4 nm ) by factor ixa in the presence of factor viiia , indicating that the generation of factor xa is not required for factor ixa binding and that factor ixa bound to activated platelets in the presence of factor viiia is closely coupled with rates of factor x activation .
C0015520
factor xa
C0015518
factor x