the preventive and therapeutic effects of 2- ( 10,11-dihydro-10-oxodibenzo [ b , f ] thiepin-2-yl ) propionic acid ( cn-100 ) on local and systemic changes of rats with adjuvant arthritis being used frequently as experimental model of rheumatoid arthritis were investigated in comparison with those of reference drugs , indometacin and pranoprofen .
C0003873
rheumatoid arthritis
C0021246
indometacin