the cells which did not form e rosettes , but stained positively with the monoclonal anti-leu-1 antibody ( e- , leu-1+ ) had certain functional capability evidenced by their ability to amount a proliferative response to t-cell mitogens , phytohemagglutinin and concanavalin a , but failed to provide t-helper-cell activity to support the differentiation of normal b lymphocytes into immunoglobulin-secreting cells following stimulation with pokeweed mitogen .
C0007634
cells
C1511002
differentiation