estromustine was the main metabolite in plasma as well as in the tumour ( range 235 to 450 and 205 to 485 ng./gm. , respectively ) , whereas estramustine ( 20 to 45 ; 95 to 370 ) , estrone ( 62 to 140 ; 63 to 160 ) and estradiol ( 8 to 15 ; 7 to 36 ) were found in lower concentrations .
C0014921
estramustine
C0014912
estradiol