a marked reduction was found in the steady-state biliary clearance of digoxin from control value 134 +/- 57 ml/min ( mean +/- sd ) to 87 +/- 39 ml/min during treatment with quinine ( p less than 0.05 ) and from 95 +/- 24 to 55 +/- 27 ml/min during treatment with quinidine ( p less than 0.01 ; n = 4 ) .
C0034417
quinine
C0034414
quinidine