however , nidd patients with impaired joint mobility had a significantly increased frequency of microvascular disease , as shown by retinopathy and/or nephropathy ( 42 % versus 22 % , p less than 0.05 ) , were more often on insulin treatment ( 86 % versus 63 % , p less than 0.05 ) and more frequently had additional rheumatic disorders such as dupuytren 's contracture and osteoarthritis ( 36 % versus 18 % , p less than 0.05 ) .
C0022417
joint
C0029408
osteoarthritis