a series of experiments was conducted to investigate the effects of alpha-msh , mif-i and melatonin on novelty-induced defecation , step-down activity , plasma 11-ohcs levels and whole brain da and ne concentrations over days of novelty x drug treatment . alpha-msh consistently enhanced and sustained novelty-induced defecation , increased plasma 11-ohcs levels in the resting intact rats and in the novelty exposed hypophysectomized ( hypox ) rats , and decreased brain da and ne levels in intact , hypox and sham-hypox rats .
C0004927
conducted
C0006104
brain