this contrasts with the activity in iddm and nonobese niddm patients ( where the g6pase/gk ratio is elevated and normal , respectively ) and would suggest that in the obese diabetic subjects , hepatic glucose production is not a major factor contributing to the maintenance of hyperglycemia in the overnight fasting state ( leaving peripheral insulin resistance as the major cause of hyperglycemia ) .
C0017725
glucose
C0020456
hyperglycemia