nineteen patients with severe oedema due to either cirrhosis of the liver or to congestive cardiac failure , who had failed to respond to previous diuretic therapy , were treated with either increasing doses of frusemide ( group a ) , or with frusemide in a fixed dose of 80 mg daily and increasing doses of spironolactone ( group b ) .
C0018802
congestive cardiac failure
C0016860
frusemide