neonatal treatment with the catecholamine neurotoxin 6-hydroxydopamine ( 6-oh-da ) leads to permanent noradrenaline ( na ) denervations of distant projections ( e.g . in the neocortex ) with a concomitant na hyperinnervation in regions close to the perikarya ( e.g . in the cerebellum ) a `` '' pruning effect ' mainly affecting the locus coeruleus na neuron system .
C0007412
catecholamine
C0028351
n