in addition , relapse following growth of hormone - insensitive cells , and the present observations of further evidence of immunosuppression demonstrated by the significant ( p less than 0.001 ) effect of des on the lytic activity of natural killer cells vs. the negligible effect of the luteinizing - hormone - releasing - hormone , leuprolide ( lupron ) raises concern that the palliative effects of oestrogen therapy are possibly further compromised by a reduction in immunosurveillance to tumour , or equally important , by a decreased capacity to cope with infectious agents .
C0023610
luteinizing
C0085272
leuprolide