amino acid sequence alignments of c. crescentus cuznsod with eucaryotic cuznsods and with cuznsod of photobacterium leiognathi ( the only other bacterium from which cuznsod has been isolated and sequenced ) suggest similar supersecondary structures for bacterial and eucaryotic cuznsods but reveal four novel substitutions in c. crescentus cuznsod : a phenylalanine critical to intrasubunit hydrophobic bonding replaced by alanine , a histidine ligand of zinc replaced by aspartate , and substitutions of two other previously invariant residues that stabilize zinc or both copper and zinc .
C0002520
amino acid
C0001898
alanine