despite its ability to block egf-stimulated growth and down-regulation in fibroblasts , the antibody was unable to block the growth and soft agar colony formation of alpha tgf-secreting melanoma cells , nor could the antibody detect egf receptor in these cells under the conditions developed to prevent down-regulation and lysosomal degradation of the egf receptor .
C0016030
fibroblasts
C0007634
cells