other characteristic degenerative signs were vacuolation of cytoplasm up to formation of great optically empty spaces , widening of the perinuclear space , swelling of mitochondria , disintegration of rhoptria , micronemata , and golgi zone , coarse-plaque loosening , and displacement of electron-dense areas of the nucleus up to disintegration with maintenance of the karyoplasm .
C0007610
nucleus
C0008546
karyoplasm