k-252a , a protein kinase inhibitor isolated from the culture broth of nocardiopsis sp. , inhibits the nerve growth factor ( ngf ) -stimulated phosphorylation of microtubule-associated protein 2 ( map2 ) and kemptide ( synthetic leu-arg-arg-ala-ser-leu-gly ) by blocking the activation of two independent kinases in pc12 cells : map2/pp250 kinase and kemptide kinase .
C0031715
phosphorylation
C0031727
kinase