percutaneous absorption of isosorbide dinitrate ( isdn ) , determined from plasma concentrations of isdn and its metabolites isosorbide 2-mononitrate ( is-2-mn ) and isosorbide 5-mononitrate ( is-5-mn ) , was studied in 8 healthy subjects aged 19 to 25 years following application of a single plaster containing 40 mg isdn to the hairless skin on the left side of the chest for 72 h .
C0022252
isdn
C0064079
isosorbide 5-mononitrate