we interpret the action of substoichiometric podophyllotoxin on microtubule ends in terms of effects on interconversion of growing and shrinking microtubules in a dynamic system in which tubulin-gtp-podophyllotoxin is kinetically analogous to tubulin-gtp in addition and to tubulin-gdp in dissociation .
C0026046
microtubule
C0041348
tubulin