this hypothesis is supported by three lines of evidence : ( a ) replacement of the chloride content of the ringer solution by the less permeant anion isethionate abolished the slow phases of the carbachol response . ( b ) reduction of chloride permeability ( by lowering ph ) caused rapid repolarization during the recovery period after carbachol . ( c ) when the membrane potential was clamped at the resting level throughout the action of carbachol , so avoiding chloride redistribution , the clamping current records did not show the slow phases attributed to chloride movement.5 .
C0003075
anion
C0008203
chloride