the acth secretion induced by histamine ( 0.5 mg/100 g ) was inhibited completely by the pretreatment with the antagonists of h1-receptor , diphenyhydramine ( hydrochloride , 0.2 -- 0.5 mg/100 g ) , promethazine ( hydrochloride , 0.1 -- 0.2 mg/100 g ) and d-chlorpheniramine ( maleate , 0.02 -- 0.05 mg/100 g ) .
C2757048
antagonists
C0546876
promethazine