we found that a single dose of 4-oxo-it , 100 mg/kg , given on day 11 of gestation ( plug day = day 0 of gestation ) produced a moderate incidence of limb reduction defects and cleft palate ( 39 % and 27 % of surviving fetuses , respectively ) , while a dose of 150 mg/kg affected virtually every fetus .
C0022265
it
C0032961
gestation