to compare in vitro and in vivo cyclosporin a ( cya ) effects on early events involved in human t cell activation , lymphocytes obtained from healthy donors and from diabetic patients undergoing cya therapy were studied for their interleukin 2 ( il-2 ) responsiveness , surface il-2 receptor ( il-2r ) expression and il-2r mrna accumulation , following stimulation with mitogen or anti-cd3 monoclonal antibody .
C0086418
human
C0021756
interleukin 2