it is likely that this reduced 1,25- ( oh ) 2d receptor number in the parathyroid glands of chronically uremic animals renders the glands less responsive to the inhibitory action of 1,25- ( oh ) 2d on the synthesis and secretion of pth , and may contribute to the hyperparathyroidism associated with chronic renal failure .
C0030518
parathyroid glands
C0020502
hyperparathyroidism