a single intraperitoneal injection of lentinan alone at concentrations of up to 10 mg/kg body weight did not render spleen cells cytotoxic to p-29 cells , but a combination of subthreshold doses of these agents ( 5 x 10 ( 4 ) u/ml il-2 and 5 mg/kg lentinan ) induced significant in vivo lymphokine-activated killer activity in spleen cells of tumor-bearing mice .
C0037993
spleen
C0037999
spleen