the ability of the two early simian virus 40 ( sv40 ) coded proteins , the large and small t-antigens , to abortively induce the disappearance of cytoplasmic actin-containing networks in cultured cells has been studied in rat embryo fibroblasts after microinjection of intact sv40 dna , dna fragments from the early region of sv40 , and a purified sv40 large t-antigen related protein ( the d2 hybrid protein ) isolated from cells infected with the adenovirus-sv40 hybrid virus ad2+d2 .
C0016030
fibroblasts
C0007634
cells