examples of this latter category include the changes in urinary hydroxyproline output in patients with bone metastases or the altered levels of serum acute phase proteins in neoplasia in general.7 tumor-derived markers may be produced by either the tumor cell population itself , e.g. , cea , alpha-fetoprotein ( afp ) , and other oncofetal antigens , inappropriate hormones such as acth etc. , or by their supporting framework ( stroma ) , e.g. , the osteolysins of human breast cancer.3
C0041365
neoplasia
C0002210
alpha-fetoprotein