after just 4 days of exposure to melatonin , mcf-7 cells exhibited reduced numbers of surface microvilli , nuclear swelling , cytoplasmic and ribosomal shedding , disruption of mitochondrial cristae , vesiculation of the smooth endoplasmic reticulum , and an increase in the numbers of autophagic vacuoles .
C0010834
cytoplasmic
C0035553
ribosomal