in guinea-pigs , gradual suprabasal movement and loss of rounded , atpase-positive langerhans cells from the epidermis were detectable from 5 to 20 days after irradiation but the magnitude of the cell loss and redistribution was partially obscured by the simultaneous appearance of clusters of replacement langerhans cells in the basal layer and by keratinocyte hyperplasia .
C0014520
epidermis
C0022567
hyperplasia