it is suggested that the initial enhancement by ethanol of brain tryptophan metabolism is caused by catecholamine-mediated lipolysis followed by displacement of protein-bound serum tryptophan , whereas the activation of liver tryptophaan pyrrolase , which is produced by the same mechanism , leads to the later decreases in the brain concentrations of tryptophan and its metabolites .
C0006104
brain
C0086045
concentrations