this report , for the first time , demonstrates that diethyl-nitrosamine ( ndea ) and a new nitrosamine compound-n-1-methylacetonyl-n-3-methylbutyl-nitrosamine ( mambna ) , which are suspicious carcinogens of esophageal cancer ( ec ) in linxian , henan province , are able to cause the malignant transformation ( altered morphology , extended life span , anchorage independent growth , invasiveness , tumorigenicity , etc . ) of normal diploid fibroblasts derived from human fetal lung .
C0012200
ndea
C0028197
nitrosamine compound