the presence of interstrand crosslinks in the dna of cis-diamminedichloroplatinum ( ii ) ( cisplatin ) -treated chinese hamster cells was demonstrated by the formation of a species of hybrid-labelled dna in cells that had been density and radioactively prelabelled with a combination of [ 3h ] thymidine and 2'-deoxy-5-bromouridine ( brdurd ) prior to treatment .
C0012854
dna
C0598312
formation