in most cases of cml and some cases of ph+ all the protooncogene abl from 9q34 is translocated to the breakpoint cluster region ( bcr ) of the bcr gene at 22q11 to form a chimeric gene encoding a novel 210-kd protein ( p210 bcr-abl ) with enhanced tyrosine kinase activity .
C0023473
cml
C1704928
abl