in a controlled , double-observer , multicenter study , we compared the effect of a fixed combination of timolol 0.5 % -pilocarpine 4 % twice a day with that of timolol 0.5 % twice a day plus pilocarpine 4 % three times a day in 80 patients with open-angle glaucoma whose intraocular pressure was greater than 21 mm hg on timolol 0.5 % twice a day alone .
C0017612
open-angle glaucoma
C0040233
timolol