these in vitro studies demonstrated that : 1 ) the spleen cells from tb rats ( tb-spleen cells ) showed strongly depressed mitogen responses to concanavalin-a ( con-a ) , phytohemagglutinin-p ( pha-p ) and lipopolysaccharide ( lps ) , 2 ) the mitogen response of lymph node cells from tb rats was slightly depressed , 3 ) the removal of plastic or nylon-wool adherent cells or phagocytic cells from tb-spleen cells resulted in a restoration of the mitogen response , 4 ) the con-a response of normal spleen cells could be suppressed by the addition of tb-whole spleen cells , 5 ) the suppressor cell activity was not abrogated by the in vitro treatment with x-irradiation ( 2000 rads ) , 6 ) carbonyl-iron treated tb-spleen cells showed a normal level of mitogen response , and on addback to normal spleen cells no suppressive activity was detected in them .
C0032167
plastic
C0028736
nylon