the biologic changes occurring in severely ischemic myocytes in vivo as the affected cells pass through the phase of reversible to the phase of lethal or irreversible injury are reviewed with special emphasis on the effect of ischemia on the production and utilization of highenergy phosphate , the destruction of the adenine nucleotide pool , and the appearance of signs of damage to the plasma membrane of the sarcolemma .
C0007634
cells
C0007603
plasma