the antiepileptic drug valproic acid ( vpa ) was administered via four different routes in the mouse during gestational stages sensitive for interference with neural tube defect formation : a single oral intubation or injection , sc or ip , on day 8 , or infusion via subcutaneously implanted osmotic minipumps from day 7 1/2 to 8 1/2 of gestation .
C0042291
valproic acid
C0032961
gestation