these data confirm that the kdo residue ( s ) present in all endotoxins play ( s ) a major role in the signal ( s ) leading to il-1 production by human monocytes , and show that il-1 induction by lps ( 1 ) requires a free carboxyl group in the kdo and ( 2 ) is correlated with the degree of substitution of the kdo .
C0014264
endotoxins
C0023810
lps