o6-methylguanine ( o6mg ) produced in dna by such sn1 methylating agents as n-methyl-n-nitrosourea and n-methyl-n'-nitro-n-nitrosoguanidine ( mnng ) has been suggested by some to be the lesion that leads to certain biological endpoints in mammalian cells : cell killing , sister chromatid exchange ( sce ) production , mutagenesis and cellular transformation .
C0007634
cell
C0037211
sister chromatid exchange