the major c21- and c19-steroids formed from progesterone by the tumors grown in the presence of estrogen were 5 alpha-steroids such as 3 alpha- or 3 beta-hydroxy-5 alpha-pregnan-20-one , 3 alpha , 17-dihydroxy-5 alpha-pregnan-20-one , androsterone , and 5 alpha-androstane-3 alpha , 17 beta-diol , whereas the major steroids formed by the tumors in the absence of estrogen were 4-ene-3-ketosteroids such as 20 alpha-hydroxy-4-pregnen-3-one , 17-hydroxy-4-pregnene-3,20-dione , and testosterone .
C0038317
steroids
C0022640
ketosteroids