given the embryologic derivatives of the ovary , which comprise gonadal ridges composed of mesodermal cells covered by coelomic epithelium , we postulate that patients with hereditary predisposition to ovarian carcinoma harbor the first germinal hit in both the epithelial cells of the ovary as well as their derivatives in the coelomic mesothelium .
C0014609
epithelium
C0014597
epithelial cells