in vitro studies using clonal assays for hematopoietic progenitors revealed that while the patient 's serum or ranitidine alone did not affect the patient 's or normal bone marrow hematopoiesis , the simultaneous presence of both agents significantly suppressed both patient 's and normal erythroid progenitor ( bfu-e ) colony development .
C0018957
hematopoietic
C0005953
bone marrow