because ir genes are certainly involved in controlling the immune response against modified autologous mhc antigens , the author forwards an original hypothesis for explaining the linkage disequilibrium between different alleles at the hla : a , b , c loci : the ir gene ( genes ) in a given haplotype is particularly efficient for recognizing some particular altered antigens of different serie ( say a1 and b8 ; a3 and b7 ) .
C0301872
immune response
C0003320
antigens