synthesis of macromolecules was perturbed in treated parasites : rates of dna and rna synthesis declined 50-100 % , while protein synthesis increased up to 4-fold in 36-h treated cells . alpha-dl-difluoromethylornithine treatment progressively limits the parasites ' ability to synthesize nucleic acids and blocks cytokinesis while inducing morphological changes resembling long slender leads to short stumpy transformation .
C0007634
cells
C0010813
cytokinesis