in order to determine whether d2-dopaminergic receptors in brain exist in different affinity states for agonists and whether these receptors could be completely converted from their agonist high-affinity state to their agonist low-affinity state , we examined the effect of a guanine nucleotide on the competition between [ 3h ] spiperone and dopamine agonists for binding to homogenates of calf caudate nucleus .
C0006104
brain
C0007461
caudate nucleus