neither low dose ( 100,000 u/kg bolus followed by 100,000 u/kg/h continuous infusion ) nor high dose ( 100,000 u/kg bolus followed by 800,000 u/kg/h ) recombinant human superoxide dismutase had an effect upon water and sodium content of whole brain at 1 h of reperfusion following 1 h of ischemia , but high-dose treatment effectively reduced brain water content at 3 h of reperfusion .
C0006104
brain
C0423896
content