to study the possible relationship between individual subclass expression and pathogenesis of antibody-mediated disease , we examined the immunoglobulin-g subclass of antiglomerular basement membrane ( gbm ) antibodies , in the sera of 20 patients with auto-antibody mediated nephritis , as well as in a limited number of kidney eluates , using a solid phase radioimmunoassay and monoclonal antibodies specific for human igg subclasses .
C0027697
nephritis
C0022646
kidney