the 24 cases of multiple myeloma were diagnosed using : -- topographical criteria : inhomogenous sharing , nests of plasmocytes exclusively away from the periphery of vessels , -- cytological criteria such as frequent cellular immaturity , nuclear immaturity in binucleated cells , bizarre shaped nuclei . . . -- immunological criteria obtained by immunofluorescence method : strictly monoclonal labelling of plasma cells or `` '' limit '' '' -monoclonal labelling in 50 % of cases .
C0026764
multiple myeloma
C0032112
plasma cells