in order to ascertain the extent of hypothalamo -- pituitary -- thyroid ( hpt ) axis dysfunction in endogenous depression , we determined nocturnal serum thyrotropin ( tsh ) concentrations , tsh responses to thyrotropin releasing hormone ( trh ) administration , and serum triiodothyronine ( t3 ) and thyroxine ( t4 ) concentrations in 40 research diagnostic criteria primary , definite endogenous depressives and 40 individually matched normal control subjects .
C0032002
pituitary
C0040162
thyrotropin releasing hormone