influx of each folate compound proceeded with approximately the same vmax , fluctuated in the same fashion with the ionic composition of the medium , and was blocked by low concentrations of an n-hydroxysuccinimide ester of methotrexate in both an anion-deficient buffer and in a buffered saline medium containing physiological concentrations of glucose and bicarbonate .
C0022023
ionic
C0003075
anion