when guanosine 3',5'-monophosphate ( cyclic gmp ) and adenosine 3',5'-monophosphate ( cyclic amp ) are localized in canine thyroid by a flurescence immunocytochemical procedure , distinct staining patterns for each nucleotide are seen : cyclic amp is distributed throughout the follicular cell cytoplasm before and after administration of thyroid-stimulating hormone , while cyclic gmp is localized to the follicular cell mumbrane in the control state , and increased cytoplasmic fluorescence is visualized after acetylcholine .
C0007634
cell
C0010834
cytoplasmic