determination by dilution analysis of the effects of vinblastine on the apparent dissociation rate constants for tubulin loss at opposite microtubule ends indicated that a principal effect of vinblastine is to decrease the dissociation rate constant at a ends ( i.e. , it produces a kinetic cap at a ends ) , whereas it has no effect on the d-end dissociation rate constant .
C0041348
tubulin
C0026046
microtubule