the ontogeny of gamma-melanocyte stimulating hormone ( gamma-msh ) -like immunoreactive ( gamma-mshi ) structures in the brain and hypophysis was investigated in the rat by means of indirect immunofluorescence . gamma-mshi neurons in the arcuate nucleus appeared at day 13 of gestation , in the anterior hypophysis at day 16 , in the intermediate lobe at day 18 , and in the nucleus commissuralis after birth . gamma-mshi fibers first appeared at day 15 of gestation in the hypothalamic area and extended dorsally to reach the surface of the diencephalon .
C0006104
structures
C0003741
arcuate nucleus