as a result of histological and ultracytochemical investigations concerning the influence of thiamine and its disulfide derivative , thiamine tetrahydrofurfuryl disulfide ( ttfd ) , on acetylcholinesterase ( ache ) in extirpated guinea pig atria , it was found that there was a clear increase in the ache activity by 10 ( -4 ) m ttfd , a weak increase with 10 ( -5 ) m and an extremely weak increase , about the same as that in only the nutrient ( locke 's solution ) , with 5 x 10 ( -4 ) m .
C0039840
thiamine
C0016865
ttfd