incubation of 3t3 fibroblasts with phosphatidic acid ( pa ) from egg lecithin or with thrombin resulted in decreases in cellular camp due to inhibition of adenylate cyclase , in rapid increases in inositol 1,4,5-tris-,1,4-bis- , and 1-monophosphates probably due to activation of phospholipase c , and in arachidonic acid release .
C0016030
fibroblasts
C0007634
cellular