recently , work in this laboratory has shown that changes in the 'dynamic ' component of fluidity , lipid composition and phospholipid methylation activity of distal colonic brush-border membranes could be detected after administration of 1,2-dimethylhydrazine to rats of the sherman strain for 5-15 weeks , i.e. , before the development of colon cancer .
C0009368
colonic
C0007102
the