airway reactivity ( assessed by the provocative concentration of methacholine causing a 20 % fall in fev1 ) correlated with both the dose of isoproterenol required for the target pulse pressure response ( rs = -0.46 ; p less than 0.05 ) and the isoproterenol-induced increase in low-frequency heart-rate variability ( rs = 0.47 ; p less than 0.05 ) .
C0022245
isoproterenol
C0428977
low