since phosphorylation of 2'-ndg creates a chiral center in the molecule , it was of interest to examine whether both monophosphate enantiomers were produced by the viral thymidine kinase , whether they both could be further phosphorylated by cellular kinases and , if so , whether the respective triphosphates were equally inhibitory to the dna polymerases .
C0031727
kinases
C0012892
dna