the discrepancy of the in vivo inhibitory effect of high alpha-amanitin concentrations on rrna synthesis versus a lack of effect on purified rna polymerase i , which presumably transcribes these genes , can be explained if continued transcription of the large rrna precursor by rna polymerase i requires ongoing transcription by rna polymerase iii , or if there is degradation ( wastage ) of rrna precursor and/or processed products in the absence of transcription by rna polymerase iii .
C0040649
transcription
C0035678
rna