fine-mapping analysis indicated that the tk gene was within a 1.2-kb avai-haeiii fragment , and dna sequencing of this region revealed an open reading frame capable of encoding a polypeptide of 176 amino acids possessing considerable homology to the tk genes of the vaccinia , variola , and monkeypox orthopoxviruses and also to a variety of cellular tk genes .
C0079941
open reading frame
C0007634
cellular