together our results indicate that optimal induction of an ige-specific response requires the exposure of b cells to a particular complex of signals that include ( a ) a signal ( s ) involving th-b cell interaction that primes b cells to receive additional signals from soluble lymphokines , ( b ) a specific b cell proliferative signal provided by lmw-bcgf , and ( c ) a specific b cell differentiation signal provided by il-4 .
C0004561
b
C1511002
b cell differentiation