activation of human peripheral blood mononuclear cells with okt3 ( 10 ng/ml ) for 48 h , followed by culture in low concentrations of il-2 ( 10 units/ml ) and tnf ( 250 units/ml ) resulted in higher cell recovery ( 50- to 3300-fold ) compared to the number of cells in the initial culture and enhanced lytic activity against both raji and fresh lung tumor targets ( mean 100-fold ) by day 30 compared to those expanded with higher concentrations of il-2 ( 100 units/ml ) alone .
C0086418
human
C0021756
il-2