the role of granule membrane constituents has been elucidated with neutrophils disrupted by nitrogen cavitation and then fractionated in percoll gradients to resolve four postnuclear fractions : cytoplasm , light membranes or gamma fraction ( site of the nadph-oxidase ) , a light granule ( beta ) fraction containing putative constituents of the nadph-oxidase ( cytochrome b-245 and an associated flavoprotein ) , and a fraction of heavy granules .
C0068355
nadph-oxidase
C0016223
flavoprotein