five patients with evaluable malignant fibrous histiocytoma ( mfh ) of bone ( three with primary tumor and two with primary tumor and metastatic disease ) were treated with preoperative chemotherapy including high dose methotrexate ( hdmtx ) with citrovorum factor rescue ( cfr ) as is used for patients with osteogenic sarcoma .
C0025677
methotrexate
C0029463
osteogenic