surface distal tubules of sprague-dawley rats made acidotic by ammonium chloride gavage ( arterial blood ph : 7.15 +/- 0.01 , [ hco3 ] : 14.8 +/- 0.5 mm ) were perfused in vivo at 8 and 24 nl/min with 4 different isoosmotic , 25 mm bicarbonate solutions : group 1 was perfused with 60 mm na , group 2 with 60 mm choline , group 3 with 60 mm choline + 3 x 10 ( -4 ) m amiloride , and group 4 with 60 mm na + 10 ( -3 ) m acetazolamide .
C0001122
acidotic
C0000981
acetazolamide