a decrease of joint space is a sensitive and early indicator of osteoarthrosis and showed that 10 weeks after intraarticular application of ibuprofen , phenylbutazone , oxyphenbutazone , flufenamic acid , niflumic acid , na-salicylate , clofezone , bumadizone and dexamethasone the degenerative alterations in the injected knee joints were more severe than by applications of chloroquine , d-penicillamine , salicylamide and indometacin .
C0031463
phenylbutazone
C0030078
oxyphenbutazone