details of cytoskeletal changes are far from clear as yet , but interference with or modulation of these particular effects infer that cytoplasmic organization is the seat of feedback control of osmotic flow rate , the basis for viability in the presence of dramatic cytosolic dilution and a major factor in the observed disparity in osmotic and diffusional permeability coefficients .
C0010834
cytoplasmic
C1383501
cytosolic