the authors studied 310 postmenopausal women in a defined population over the period 1974-1981 to evaluate whether hysterectomy and certain other characteristics predicted change in postmenopausal estrogen use status during this period and , as a secondary issue , whether women who subsequently began postmenopausal estrogen use had different characteristics prior to use , an important question in the evaluation of the relation of postmenopausal estrogen use to morbidity and mortality from cancer , cardiovascular disease , or other diseases in observational studies .
C0007222
cardiovascular disease
C0012634
diseases