this report shows that , in 8- to 10-month-old balb/c mice immunized intraperitoneally with dextran b1355 , approximately 75 % of igg3 anti-alpha ( 1 -- -- 3 ) polyglucan ( anti-dex ) plaque-forming cells ( pfc ) detected in the spleen were identified as double-ig class producers secreting simultaneously igg3 and igm antibodies with the same specificity for the dex epitope .
C0007634
cells
C1327616
secreting