further characterisation of the amplification factor revealed that ( 1 ) the sf of ra patients augmented both the pha and the concanavalin a response of the thymocytes ( 2 ) in the absence of mitogens , sf-treated thymocytes showed an increased uptake of 3h-thymidine , ( 3 ) the sf did not propagate the growth of an interleukin 2 dependent ovalbumin specific t cell clone , but ( 4 ) the sf were found to be required for optimal interleukin 2 release by spleen cells stimulated with suboptimal doses of lectin .
C1515126
growth
C0007634
cells