a series of novel omega- ( n , n , n-trialkylammonium ) alkyl ester and thioester derivatives [ rcom ( ch2 ) nnr3+ x- , m = o or s. n = 2-6 , x = i or cl ] of 11 nonsteroidal antiinflammatory carboxylic acid agents ( naproxen , ketorolac , indomethacin , ibuprofen , sulindac , ketoprofen , flufenamic acid , mefenamic acid , zomepirac , etodolac , and tifurac ) was prepared and evaluated for their antiinflammatory , analgesic , and gastrointestinal erosive properties .
C0014898
ester
C0007066
carboxylic acid