employing brain microdialysis techniques , we have examined the effects of the enantiomers of cis-8-hydroxy-1-methyl-2- ( di-n-propylamino ) tetralin ( alk-3 ; 0.01-0.3 mg/kg s.c. ) , its trans-1-methyl analogue ( alk-4 ; 0.3 mg/kg s.c. ) and the pure enantiomers of the parent compound -- 8-oh-dpat ( 0.3 mg/kg s.c. ) -- in an attempt to address stereochemical agonist structure-activity requirements of 5-ht release-controlling 5-ht1a autoreceptors in brain .
C0663443
alk-4
C0006104
brain