in a randomized , double-blind , placebo-controlled trial , 227 us adults with acute diarrhea in mexico received a single dose of sulfamethoxazole and trimethoprim ( 1600/320 mg ) or 3 days of therapy with loperamide hydrochloride ( 4-mg loading dose , then 2 mg orally after each loose stool ) , sulfamethoxazole-trimethoprim ( 800/160 mg orally twice daily ) , or the combination of both .
C0041041
trimethoprim
C0041044
sulfamethoxazole-trimethoprim