to determine whether a similar potential for hyperosmolarity-induced depression also exists in cardiac muscle , right ventricular papillary muscles from cats were exposed to hypertonic solutions of mannitol or sucrose under circumstances in which positive inotropic effects were precluded by prior exposure to a bathing solution of 4.0 mm ca2+ and paired electrical stimulation to maximize intracellular ca2+ before addition of the hyperosmotic substances .
C0027061
cardiac muscle
C0030352
papillary muscles