as the gastroprotective activities of both de-nol and sucralfate on ethanol lesions can be reversed by pretreatment with indomethacin and as de-nol and sucralfate increase the mucosal generation and luminal release of pge2 , we postulate that mucosal prostaglandins may be involved in the mechanism of action of these drugs on the gastric mucosa .
C0012472
pge2
C0033554
prostaglandins