the binding of chromomycin a3 , an antitumour antibiotic , to various dna and chromatin isolated from mouse and rat liver , mouse fibrosarcoma and yoshida ascites sarcoma cells was studied spectrophotometrically at 29 degrees c in 10-2 m tris-hcl buffer , ph 8.0 , containing small amounts of mgcl2 ( 4.5-10-5 -- 25-10-5 m ) .
C0008546
chromatin
C0007634
cells