to elucidate whether or not histamine can be released by antigen from the nasal surface layer in sufficient quantities to produce nasal manifestation of allergy and which among three factors , i.e. , the number of surface basophilic cells , the histamine release from these cells , or the mucosal histamine sensitivity , is the most responsible for the degree of nasal allergen provocation , we determined the allergen-induced histamine release from specimens of the mucus-epithelial layer of patients with nasal allergy and also counted the number of basophilic cells in these specimens after staining by hansel 's method .
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of surface
C0007634
the