on the basis of these observations , it seems reasonable to conclude that the narcotics inhibit the secretion of lh , by an action either in the hypothalamus ( e.g. , suppression of lh-releasing hormone ) or directly in the pituitary gland , which leads to a reduction in serum testosterone levels and a subsequent reduction in the wet-tissue weight and secretory activity of the secondary sex organs .
C0020663
hypothalamus
C0023610
lh-releasing hormone