to study the structure and the molecular mechanisms of action of brain alpha-adrenoceptors , their solubilization was undertaken . alpha 1-adrenoceptors were first successfully solubilized from fresh rat brain membranes by treatment with 0.3 percent deoxycholate , after prelabeling of the binding site by the highly specific tritiated antagonist 3h-prazosin .
C0034784
alpha-adrenoceptors
C0001638
alpha 1-adrenoceptors