to test the hypothesis that non-steroidal anti-inflammatory drugs ( nsaids ) accelerate the progression of osteoarthritis by reducing synthesis of vasodilator prostaglandins , thereby diminishing joint perfusion , 105 osteoarthritis patients awaiting hip arthroplasty were treated prospectively with a strong or weak prostaglandin synthesis inhibitor , indomethacin or azapropazone , respectively .
C0022417
joint
C0029408
osteoarthritis