to clarify whether tsh binding inhibitor immunoglobulins ( tbii ) are antibodies to the membrane site associated with the tsh receptor itself or its neighboring sites , the interactions of tsh and tbii with soluble tsh receptor were investigated with a tsh radioreceptor assay using labeled highly purified bovine tsh ( btsh ) and triton extracts from guinea pig crude fat cell membranes ( 800-10,000 x g fraction ) .
C0021027
immunoglobulins
C0003241
antibodies