prolyl 4-hydroxylase is inhibited competitively with respect to ferrous ion by several bivalent cations , especially zinc , with respect to 2-oxoglutarate by pyridine 2,5-dicarboxylate , pyridine 2,4-dicarboxylate , 3,4-dihydroxybenzoate and many related compounds , with respect to oxygen by superoxide dismutase-active copper chelates and with respect to the peptide substrate by a number of peptides .
C0022023
ion
C0007447
cations