we assayed extracts of the clones for the activities of 10 enzymes important for de novo purine synthesis and found that , in addition to gart , two other purine pathway activities , phosphoribosylamine-glycine ligase ( phosphoribosylglycinamide synthetase , gars ) and phosphoribosylformylglycinamidine cyclo-ligase ( phosphoribosylaminoimidazole synthetase , airs ) , are similarly overproduced .
C0220781
synthesis
C1414989
gart