the excretion of 5-oxoproline/creatinine ( mumol/mmol ) rose progressively as pregnancy advanced ( non-pregnant mean 10 , sd 5 , first trimester mean 46 , sd 12 , second trimester mean 150 , sd 180 , and third trimester mean 280 , sd 320 ) and by the third trimester was over 20 times greater than in non-pregnant women .
C0032961
pregnancy
C0032980
second trimester