to determine the antisteroidogenic effect of ketoconazole ( ktz ) in the human testis , we measured the plasma delta 5-pregnenolone , delta 5-17 alpha-hydroxypregnenolone , dehydroepiandrosterone ( dhea ) , progesterone , 17 alpha-hydroxyprogesterone , androstenedione ( a ) , and testosterone ( t ) concentrations in three men with previously untreated metastatic prostate cancer at various time intervals for 24 h before and 48 h after the administration of 200 mg oral ktz every 8 h .
C0373704
pregnenolone
C0376260
17