as approximately two-thirds of aids patients appear to be in negative balance with respect to folate and/or vitamin b12 , the fact that azt-induced inhibition of pyrimidine incorporation into dna is occurring in cells which may be megaloblastic , i.e. , in a state of impaired dna synthesis , suggests that these cells may be more susceptible to azt toxicity .
C0012854
dna
C0598312
dna