the effects of a cardioselective beta-adrenoceptor blocker without intrinsic sympathomimetic activity ( isa ) ( atenolol ) and a noncardioselective beta-adrenoceptor blocker with isa ( bopindolol ) on circadian heart rate were studied in 10 patients ( 2 women and 8 men ) with an average age of 52 years and the following diagnoses : coronary heart disease ( n = 4 ) and hypertension ( n = 6 ) .
C0004147
atenolol
C0020538
hypertension