we investigated the methylation reaction catalyzed by 1500-fold purified rat liver dna methyltransferase ( dmase ) on native micrococcal luteus dna ( ml-dna ) and poly ( dc-dg ) templates containing covalently bound ( + ) -7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo [ a ] pyrene ( anti-bpde ) , the strongly carcinogenic , principal metabolite of benzo [ a ] pyrene .
C0025723
methylation
C0012873
dna methyltransferase