patients with sustained atrial fibrillation or flutter for more than 2 hours ' duration , stable hemodynamic status , and prior digoxin therapy were randomized to receive either intravenous amiodarone , 5 mg/kg over 20 minutes ( 41 patients ) , or oral quinidine , 400 mg immediately and 400 mg in 4 hours ( 39 patients ) , with cross-over at 8 hours if reversion was not achieved .
C0004238
atrial fibrillation
C0034414
quinidine