the mutagenic and carcinogenic substance benzo [ a ] pyrene reacts with dna following activation to its corresponding 7,8-diol 9,10-epoxide ( bpde ) , and the major dna adduct ( bp-n2-gua ) is formed when the c ( 10 ) -position of bpde reacts with the n2-position of guanine .
C0012854
dna
C0242958
dna adduct