chronic myelogenous leukemia ( cml ) is associated with the reciprocal translocation of a region of chromosome 22 called bcr with the c-abl gene of chromosome 9.5 ' coding sequences from the bcr gene are spliced in-frame to the second exon of the abl gene to produce a cml-specific 8.5 kilobase message which encodes the bcr-abl hybrid protein p210 .
C0023473
cml
C3274672
bcr-abl