specific nuclear binding sites are localized in the distal parts of the nephron , with some variations according to the steroid hormone considered : target cells for aldosterone are located in the distal tubule and cortical collecting duct , glucocorticoid receptors are present in all distal segments , whereas those of 1-25 ( oh ) 2d3 are restricted to the thick ascending limb of henle 's loop and to the medullary collecting tubule .
C0027713
nephron
C0227658
ascending limb of henle 's loop