the fetal prostacyclin synthesis , as assessed by the production of 6-ketoprostaglandin f1 alpha ( a metabolite of prostacyclin ) by the umbilical artery , was reduced from 21.3 +/- 1.6 ng/gm/min of dry weight in the controls ( n = 25 , mean +/- se ) to 7.8 +/- 1.1 ng/ml/min ( p less than 0.001 ) in infants of mothers receiving 500 mg of acetylsalicylic acid , but it was unchanged in infants with mothers receiving 100 mg of acetylsalicylic acid ( 19.5 +/- 2.3 ng/gm/min ) .
C0021270
infants
C0004057
acetylsalicylic acid