our objectives were to test whether pretreating the human rectum with an enema of 400 micrograms of a prostaglandin e1 analog ( misoprostol ) would ameliorate the mucosal injury provoked by an enema of 10 mg of bisacodyl , and to follow the evolution of the bisacodyl-induced injury in normal volunteers .
C0691211
enema
C0005632
bisacodyl