as scid mice appear to contain early lymphoid cells committed to the b lineage ( pro-b cells ) , we asked whether the introduction of an igm heavy-chain gene alone ( mu-transgenic scid mice ) or both igm heavy- and kappa light-chain genes ( mu kappa-transgenic scid mice ) would allow further differentiation of scid pro-b cells into pre-b and b cells .
C1292769
pre-b
C0004561
b cells