in assessing the humoral immunoregulatory status in patients with inflammatory bowel disease , we found that the antibody production by the b cells that spontaneously secrete tetanus-specific immunoglobulin g in vitro , and which occur in the circulation 7 days postimmunization , was highly variable and below normal in the majority of crohn 's disease and ulcerative colitis patients .
C0021390
inflammatory bowel disease
C0010346
crohn 's disease