in 13 dogs who received all four drug treatments ( mexiletine , quinidine , combination and placebo ) significantly greater antiarrhythmic efficacy was seen with combination therapy ( 8 of 13 ) than was seen with mexiletine alone ( 1 of 13 ) , quinidine alone ( 3 of 13 ) and saline ( 0 of 13 ) ( p less than .005 ) .
C0025887
mexiletine
C0003195
antiarrhythmic