this protracted delay in the onset of puberty can not be accounted for by the `` '' gonadostat '' '' hypothesis , which states that increased sensitivity of the hypothalamic gnrh oscillator to gonadal steroid feedback is an essential feature of the prepubertal inhibition of gonadotropin secretion , because orchidectomy during neonatal development does not interrupt the prepubertal suppression of lh and fsh secretion .
C0018067
o gonad
C0029189
orchidecto