whereas the beta 2 adrenoceptor agonist salbutamol ( 1 microm ) and the membrane permeable analogue of cyclic amp , 8-bromo-cyclic amp ( 1 mm ) were without effect upon total [ 3h ] inositol phosphate formation induced by carbachol , 3-iso-butyl-1-methylaxanthine ( ibmx ) ( ec50 140 microm ) , the high km , cyclic amp selective phosphodiesterase inhibitor rolipram ( ec50 41 microm ) and theophylline ( ec50 76 microm ) all inhibited the inositol phosphate response to low ( 1 microm ) concentrations of carbachol .
C0001455
cyclic amp
C0000661
8-bromo-cyclic amp