since neither saralasin ( 0.5 mum ) , a competitive antagonist of angiotensin ii , nor meclofenamate ( 6.8 mum ) , an inhibitor of prostaglandin synthesis , depressed hypoxic pressor responses , it was concluded that these humoral transmitters were not directly involved in the hypoxic mechanism , and therefore served as independent reference agonists .
C0036193
saralasin
C0003009
angiotensin ii