in 19 parkinsonians with prominent dose-by-dose fluctuations , double-blind crossover trials comparing 8-week regimens of standard carbidopa/levodopa ( 25/100 ) to sinemet cr ( 50/200 ) showed comparable clinical outcomes , with mean daily dosing for optimal control reduced from 10.2 to 5.4 ( although mean daily levodopa dosage increased from 1,340 to 1,781 mg/day ) .
C0353697
carbidopa/levodopa
C0023570
levodopa