although the mechanism ( s ) by which lead induces mutations is unknown , failure of both compounds to induce sce and dna single-strand breaks , detectable by alkaline elution , suggests that lead-induced mutations may not be a result of direct damage to dna but may occur via indirect mechanisms including disturbances in enzyme functions important in dna synthesis and/or repair , or in dna-helical structure .
C0012854
dna
C0598312
dna synthesis