furthermore , sce frequency was the most sensitive toxicological endpoint to detect embryotoxic effects of cpa treatment before implantation , since it was significantly increased in embryos exposed to 5 mg/kg cpa on day 2 of pregnancy while embryolethality at term and both cytogenetical ( structural chromosomal aberrations , micronuclei ) and developmental parameters ( cell number , differentiation in culture ) before implantation did not indicate any toxic effect .
C0010583
cpa
C0032961
pregnancy