to help better understand the role of changes in cellular cation homeostasis in the pathogenesis of renal tubular cell injury , the alterations in cation content of renal cortex and isolated renal cortical mitochondria occurring during models of nephrotoxicity secondary to gentamicin and hgcl2 were determined both during a developing phase of injury prior to the appearance of cell necrosis and after advanced injury when cell necrosis was present .
C0026237
mitochondria
C0007634
cell