the studies suggest that the use of a combination of anticholinergic and beta 2-adrenergic drugs is justified , because the dominant mechanism in bronchospasm is the effect of acetylcholine on muscarinic receptors and because ipratropium bromide increases the action of fenoterol , so as to obtain prolonged bronchospasmolytic and antibronchoconstrictive effects with halved doses of beta 2-agonist .
C0006266
bronchospasm
C0700580
ipratropium bromide