we have previously described the development of transcriptional test systems using these templates that can sensitively detect changes in promotor or terminator recognition of an rna polymerase ( wiggs , j.l. , bush , j.w. , and chamberlin , m.j. ( 1979 ) cell 16 , 97-109 ) or changes in the rate of any of the major steps of the transcription cycle ( chamberlin , m.j. , nierman , w.c. , wiggs , j.l. , and neff , n. ( 1979 ) j. biol . chem . 254 , 10061-10069 ) .
C0035681
rna polymerase
C0040649
transcription