using the human c-erbb-2 cdna as a probe , we applied in situ hybridization techniques to acute promyelocytic leukemia cells with a 15 ; 17 chromosome translocation , t ( 15 ; 17 ) ( q ; 22 ; q21 ) , and were able to localize the c-erbb-2 gene on chromosome 17 to band q12 or q21 and on the proximal side of the breakpoint in the translocation .
C0086418
human
C0243036
erbb