the pharmacokinetics and thrombolytic properties of a variant of human tissue-type plasminogen activator ( t-pa ) , obtained by deletion mutagenesis of the nh2-terminal fibronectin-like finger ( f ) and epidermal growth factor ( e ) domains , and substitution of the three known glycosylated asn residues by gln ( t-pa-delta fe3x ) , were studied in dogs with a copper coil-induced thrombosis of the left anterior descending coronary artery .
C0086418
human
C0242275
epidermal growth factor