in order to investigate an effective administration method for ok-432 , a potent biological response modifier ( brm ) , in patients with cervical cancer , preoperative local administration was conducted and the following results obtained : immunohistochemical examination using monoclonal antibodies indicated that the group given local injection of ok-432 showed a marked increase in ia antigen-positive t4 cells , ia antigen-positive macrophages and nk cells in the tissue of the area surrounding the cervical cancer and in regional lymph nodes compared with the non-injection group .
C0039215
t4 cells
C0019630
ia antigen