most importantly , repeat bone biopsies showed that high doses of calcitriol and phosphorus supplements had reversed the mineralization defect in all patients ( mineral apposition rate , 0.88 +/- 0.04 micron/d ) and consequently reduced parameters of bone osteoid content to normal ( relative osteoid volume , 4.1 +/- 0.7 % ; mean osteoid seam width , 11.0 +/- 1.0 micron ) .
C0005933
bone biopsies
C0262950
bone