since the nzb/w mouse is a good animal model for human systemic lupus erythematosus and sjogren 's syndrome and since tibolone , lynestrenol , and ethylestrenol have endocrinological profiles which are not prohibitive for treatment of male and female patients , investigation whether these compounds have a value in the treatment of human autoimmune diseases seems warranted .
C1527336
sjogren 's syndrome
C0004364
autoimmune diseases