it was shown that prolonged administration of sympatholytics ( ornide or actadine ) and also of a blocker of the alpha-adrenorecptors with phentholamine or of beta-adrenoreceptors with inderal led to the accumulation of zinc in the cytoplasm of beta-cells , reduction of the content in them of specific aldehyde-fuchsinophilic granularity , neoformation of the islands of langerhans and to increase in the animal sensitivity to the exogenous insulin .
C0030281
beta-cells
C0022131
of