st 587 [ 2- ( 2-chloro-5-trifluoromethylphenylimino ) imidazolidine ] , a highly alpha 1-selective agonist which easily penetrates into the brain , up to 20 mg/kg i.p . exerted no effects on the thresholds for electroshock and pentylenetetrazol-induced seizures in mice and rats , but displayed significant anticonvulsant efficacy in kindled rats and epileptic gerbils .
C0036572
seizures
C0014544
epileptic