electrophoretic analysis of non-histone proteins revealed two reproducible effects of feeding the carcinogenic diet : relative to the bulk of nuclear non-histone protein , there was a reduction in the amount of a slightly basic 65000 mol . wt . polypeptide , and an increase in the level of a high molecular weight protein that was almost undetectable in material from normal rats .
C0028589
nuclear
C0019652
histone