the cytotoxicity of ketoconazole showed a dose- and time-dependent pattern , with the following concentrations inhibiting 90 % of the growing colonies ( ic90 ) : mcf 7 ( human breast cancer ) 7.25 micrograms/ml , t 47 d ( human breast cancer ) 9.0 micrograms/ml , miapaca ( human pancreatic carcinoma ) 10.0 micrograms/ml , colo 357 ( human pancreatic carcinoma ) , 9.5 micrograms/ml , hct 8 ( human colonic adenocarcinoma ) 27.1 micrograms/ml , du 145 ( human prostatic cancer ) 40.0 micrograms/ml , ar 42 j ( rat pancreatic carcinoma ) 9.0 micrograms/ml , and l1210 ( murine leukemia ) 8.6 micrograms/ml .
C0009368
colo
C0338106
colonic adenocarcinoma