as a continuation of a previous controlled trial using `` '' high-dose '' '' metronidazole as a specific sensitizer of hypoxic cells , we used a more efficient nitroimidazole derivative ( misonidazole , miso ) in combination with higher doses of radiation in patients with supratentorial high-grade astrocytomas .
C0028179
nitroimidazo
C0026218
( misonidazo