the ability of purified tryptase to promote collagenolysis was demonstrated in a dose-dependent fashion using latent collagenase derived from rheumatoid synovium , synovial fluid , il-1-stimulated cultured synoviocytes , and partially purified latent collagenase derived from conditioned media , with between 10 and 92 % of the collagen substrate degraded .
C0039099
synovium
C0224522
synoviocytes