the recent development of several specific competitive inhibitors of the rate-limiting enzyme in cholesterol biosynthesis ( 3-hydroxy-3-methylglutaryl-coenzyme a reductase , hmg coa reductase ) has opened up an important new avenue of therapy for patients with hypercholesterolemia who are not responsive to dietary treatment alone .
C0063164
3-hydroxy-3-methylglutaryl-coenzyme a reductase
C0020374
hmg coa reductase