the prolonged administration of imipramine and electroshock , as well as other antidepressant treatments , e.g . administration of the monoamine oxidase inhibitor pargyline or atypical antidepressants such as trazodone , mianserin citalopram , fluoxetine , inhibit the interaction between beta- and-alpha-adrenoceptors ( with the alpha 2-subtype playing a major role ) and may thus contribute to the phenomenon known as the beta-adrenoceptor down-regulation .
C0020934
imipramine
C0003289
antidepressant