leukemic cell and plasma concentrations of daunorubicin were examined serially in a patient with acute lymphoblastic leukemia following administration of the drug by two different regimens : regimen a-an iv bolus dose of 50 mg/m2 , and regimen b-a loading dose of 15 mg/m2 followed by 35 mg/m2 infused over 4 hours .
C1517806
leukemic cell
C0023449
acute lymphoblastic leukemia