the binding of methotrexate ( mtx ) to igg in conjugates was examined by studies on a direct mtx conjugate with a monoclonal antibody ( amm46 ) to mouse mammary tumor mm46 cells and corresponding irrelevant antibody and normal gamma-globulin conjugates , all prepared by the active ester method with mtx n-succinimidyl ester ( mtx-osu ) .
C0003250
monoclonal antibody
C0003241
antibody