in untreated dogs ( n = 7 ) under pentobarbital anesthesia ( with adrenal hormone release measured directly by cannulation of the adrenolumbar veins ) cumulative nicotine infusions ( 1-24 micrograms/kg/min i.v . ) caused dose-dependent release of epinephrine ( from 3.0 +/- 0.7 to 111 +/- 30 micrograms/kg/min ) and norepinephrine ( from 0.4 +/- 0.1 to 11.2 +/- 3.1 ) .
C0014563
epinephrine
C0028351
norepinephrine