further studies of ara-a and deoxyadenosine phosphorylation in wild-type and resistant cell lines disclosed that , although deoxycytidine kinase is the principal enzyme for their phosphorylation in vitro , their intracellular conversion to cytotoxic nucleotides depends on the joint action of deoxycytidine kinase and adenosine kinase rather than purine-specific deoxynucleoside kinase , as previously thought .
C0031715
phosphorylation
C0011486
deoxycytidine kinase