this result , along with the comparisons of gel profiles for different extents of digestion , suggests that removal of histone h1 from nuclei results in an increased susceptibility of the dna to staphylococcal nuclease at one or both ends of many of the core particles and that a strong block to further digestion occurs within these core particles resulting in the formation of a relatively stable 102-bp fragment .
C0019644
histone h1
C0007610
nuclei