when serum urate was reduced in normal subjects and 30 patients to a mean of 2.1 and 2.3 mg/dl , respectively , probenecid elicited a significantly lower urate excretion rate in gout ( 532 +/- 202 micrograms/min/1.73 m2 ) than in controls ( 922 +/- 136 micrograms/min/1.73 m2 ; p less than 0.01 ) .
C0033209
probenecid
C0018099
gout