none of the other kinetic properties of the enzyme including the affinity for substrate , sensitivity to guanine nucleotide and fluoride activation , and cholera toxin-induced modification of enzymic activity were affected by treatment of islets with iap , suggesting that neither the catalytic nor the gtp-regulatory component of the membrane adenylate cyclase complex is the site of iap action .
C0018328
guanine
C0018353
gtp