because salicylates are the agents most commonly employed in treatment of osteoarthritis and because we recently showed that 10 ( -3 ) m sodium salicylate ( i.e. , approximately 20 mg % ) suppresses proteoglycan synthesis in normal canine knee cartilage in vitro , we have studied the effects of this compound on osteoarthritis knee cartilage from dogs whose anterior cruciate ligament had been transected 9 weeks previously .
C0029408
osteoarthritis
C0409959
osteoarthritis knee