by utilizing the y-1 cell line , which is tumorigenic and responds to corticotropin by secreting steroids , and the amt-bu-a1 ( amt ) cell line , which is nontumorigenic and does not respond to corticotropin but has a nuclear marker , brdurd ( r ) , and a cytoplasmic marker , cap ( r ) , we have reconstituted cells containing y-1 karyoplasts and amt cytoplasts .
C0010834
cytoplasmic
C0007634
cells