the strong reduction in prl secretion and the restoration of the prl response to trh by 0.1 microgram/kg x min da infusion in high majority of hyperprolactinemic patients , seem to indicate that both prl hypersecretion and abnormal prl response to trh in women with pathological hyperprolactinemia are due to a relative da deficiency at the da receptor site of the pituitary lactotrophs .
C0040162
trh
C0032002
pituitary