the purposes of these studies were as follows : ( a ) to compare gastric acid secretion throughout an entire 24-h period in 8 patients with duodenal ulcer disease and in 7 normal subjects , and ( b ) to determine in duodenal ulcer patients to what extent total , 24-h acid secretion was reduced by oral cimetidine ( n = 7 ) or parietal cell vagotomy ( n = 7 ) .
C0013295
duodenal ulcer
C0008783
cimetidine