using cell suspensions treated with 0.005 % saponin which selectively permeabilizes the plasma membrane in 95-98 % of the cells , it was possible to show clearly that the intracellular ca2+ pump mechanism is of non-plasma membrane origin and therefore can be compared directly with the ca2+ pump characterized in detail in synaptosomal membrane vesicles ( gill , d. l. , grollman , e. f. , and kohn , l. d. ( 1981 ) j. biol . chem . 256 , 184-192 ; gill , d. l. , chueh , s. h. , and whitlow , c. l. ( 1984 ) j. biol . chem . 259 , 10807-10813 ) which was proven by flux reversal studies to be derived from the neural plasma membrane ( gill , d. l. ( 1982 ) j. biol . chem . 257 , 10986-10990 ) .
C0007634
cell
C0007603
plasma