in comparison to the 4,392 children older than 1 year , entered on the same studies , infants had a significantly ( p = .0001 ) increased incidence of leukocytosis , hepatosplenomegaly , meningeal leukemia at presentation , hypogammaglobulinemia , and failure to achieve complete remission ( cr ) status by day 14 of induction therapy .
C0008059
children
C0021270
infants