among these peptides , the followings were found to be most sensitive substrates for individual enzymes : boc-asp ( obzl ) -pro-arg-nh-mec ( kcat = 160 s-1 , km = 11 microm , kcat/km = 15,000,000 m-1 s-1 ) for human alpha-thrombin , z-less than glu-gly-arg-nh-mec ( kcat = 19 s-1 , km = 59 microm , kcat/km = 320,000 m-1 s-1 ) for bovine factor xa , boc-gln-gly-arg-nh-mec ( kcat = 5.8 s-1 , km = 140 microm , kcat/km = 42,000 ) for bovine factor xiia , boc-asp ( obzl ) -ala-arg-nh-mec ( kcat = 9.2 s-1 , km = 120 microm , kcat/km = 77,000 m-1 s-1 ) for bovine activated protein c , and boc-gly-phe-arg-nh-mec ( kcat = 29 s-1 , km = 230 microm , kcat/km = 130,000 m-1 s-1 ) for bovine plasma kallikrein .
C0086418
human
C0313532
plasma kallikrein