in the present study , recombinant tgf-beta 1 precursor was shown to bind to the insulin-like growth factor ( igf ) -ii/mannose 6-phosphate ( man6p ) receptor on the plasma membrane of cells since : 1 ) insulin , which induces an increase in cell surface igf-ii/man6p receptors on adipocytes , caused a 2.7-fold increase in tgf-beta 1 precursor binding to adipocytes ;
C1334090
insulin-like growth factor
C1334189
igf-ii