immunocytochemical evidence indicated that tpa induced a redistribution ( outward ) of pkc to the plasma membrane in tpa-sensitive hl60 cells , whereas it caused a translocation ( inward ) of the enzyme to the nucleus or the perinuclear region in k562 , cho , and e7sks cells , which are resistant to tpa in terms of cell growth and differentiation .
C0007603
plasma membrane
C0007634
cells