treatment caused the formation of featherless skin areas which exhibited an early maturation of the epidermis , a uniform distribution of interstitial collagen and rarefaction of fibronectin in the dermal extracellular matrix , and a significant increase of collagen content and proline incorporation in collagen noncollagen proteins , characterized by an increased hydroxyproline-to-proline ratio .
C0020388
hydroxyproline
C0033382
proline