leading strand dna synthesis of pub110 , starting by a nick at the plasmid replication origin ( oriu ) , is performed by dna polymerase iii , since replication is blocked at non-permissive temperature in thermosensitive mutants dnad , dnaf , dnah and dnan known to cause thermosensitivity of the various subunits of dna polymerase iii .
C0598312
replication
C0012890
dna polymerase iii