contrary to the in vitro findings that dhea inhibits glucose-6-phosphate dehydrogenase ( ec 1.1.1.49 ) , thus leading to the hypothesis that dhea inhibits fat synthesis by diminishing the availability of nadph , the [ nadp+ ] / [ nadph ] ratios calculated from the 6-phosphogluconate dehydrogenase ( ec 1.1.1.44 ) , isocitrate dehydrogenase ( ec 1.1.1.42 ) and malic enzyme ( ec 1.1.1.40 ) redox couples were no more oxidized in the dhea-treated animals than in the control animals .
C0017757
glucose-6-phosphate dehydrogenase
C0220781
synthesis