at the lowest dose , venous plasma iso averaged 48 pg/ml and was associated with increased heart rate ( 9 % ; p less than 0.001 ) , cardiac index ( 20 % ; p less than 0.001 ) , and stroke volume ( 9 % ; p less than 0.02 ) and decreased total peripheral resistance index ( -21 % ; p less than 0.001 ) .
C0022245
iso
C0039231
increased heart rate