taken together , the present evidence for the existence of a specific cytoplasmic afp-binding protein in mcf-7 cells and previously reported evidence for de novo synthesis of free immunoreactive and bound nonimmunoreactive forms of cytoplasmic afp by mcf-7 cells is consistent with the conclusion that most of the endogenous afp synthesized in breast cancer cells is rapidly bound to specific cytoplasmic afp-receptors , and that binding of afp to these receptors masks its immunoreactivity .
C0010834
cytoplasmic
C0206587
cytoplasmic