this article will cover the renal handling of the aminoglycosides , the pathogenetic mechanisms of nephrotoxicity , and the clinical aspects of aminoglycoside induced acute renal failure with particular emphasis on recent data which have increased our understanding of the interaction of aminoglycosides with the renal tubular cell and the effects of this interaction on cellular function and integrity .
C0022646
renal
C0022660
acute renal failure