twice-weekly application to mouse skin of 10 nmol of the potent tumor promoter , 12-o-tetradecanoylphorbol-13-acetate ( tpa ) , beginning at 3 weeks after topical application of 1.2 mumol of 7,12-dimethylbenz [ a ] anthracene ( dmba ) , was found to cause a rapid loss of persistent dmba-dna adducts from both epidermal and dermal dna .
C0000702
a
C0012854
dna