these results support the hypothesis that the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine produces a clinical syndrome , indistinguishable from parkinson 's disease , via a selective destruction only of neurons with perikarya in the substantia nigra pars compacta and the ventral tegmental area .
C0027882
neurons
C0599444
perikarya