investigation into the hormonal regulation of phosphofructokinase reveals that glucagon stimulates phosphorylation of phosphofructokinase which results in decreased affinity for fructose-2,6-p2 appears to be due to the decreased synthesis by inactivation of fructose-2,6-p2,2-kinase and increased degradation as a result of activation of fructose-2,6-bisphosphatase .
C0031715
phosphorylation
C0031727
kinase