treatment of mice with endotoxin ( lipopolysaccharide , lps ) and the two lps-induced monokines , tumor necrosis factor ( tnf ) and interleukin-1 ( il-1 ) , caused a depression of liver cytochrome p-450 and related drug-metabolizing enzymes , as well as other acute-phase changes including increase in plasma fibrinogen levels and hypoferremia .
C0014264
endotoxin
C0023810
lps