the biochemical and functional properties of the thymidine kinase ( tk ) of the herpes simplex virus type 1 mutant r100 , that is highly resistant to 9- ( 2-hydroxyethoxymethyl ) guanine ( acyclovir ) , are reported in comparison with the properties of its parental strain , wt .
C0018321
guanine
C0001367
acyclovir