lysosomes obtained from livers of uremic mice sacrificed at different time intervals demonstrated a lability of the lysosomal membranes ( as determined by the acid phosphatase activity in mu/mg ) which was maximal at 4-6 h of urethral ligation , declining towards normal at 24 and 48 h , despite an increase in the animal 's blood urea .
C0024369
lysosomes
C0230812
of the lysosomal membranes