however , significant depression of sinus nodal automaticity occurred with propafenone concentrations above 5.10 ( -6 ) m in the presence of cholinergic or complete autonomic blockade with atropine ( 10 ( -6 ) m ) and propranolol ( 5.10 ( -5 ) m ) .
C0033429
propafenone
C0033497
propranolol