the usefulness of two alpha-2 adrenergic agonists ( clonidine and guanfacine ) and their comparative effectiveness were evaluated regarding the control of the opiates abstinence syndrome and the secondary effects , including development of cardiovascular abnormalities , in 88 parenteral heroin abusers admitted to two hospital units for the treatment of addiction .
C1373110
alpha-2 adrenergic agonists
C0079466
guanfacine