this study assessed the possible interactions of the cyclooxygenase inhibitor indobufen with one sulphonylurea , glipizide , and with two beta-adrenoceptor antagonists , one of which is extensively metabolised already in the first passage through the liver ( propranolol ) while the other essentially escapes biotransformation ( atenolol ) .
C0038766
sulphonylurea
C0017642
glipizide