binding studies using the enantiomers of the synthetic cannabinoid 7-hydroxy-delta 6-tetrahydrocannabinol 1,1-dimethylheptyl homolog in preparations of rat brain cortical membranes reveal that the ( + ) - ( 3s,4s ) enantiomer hu-211 blocks n-methyl-d-aspartate ( nmda ) receptors in a stereospecific manner and that the interaction occurs at binding sites distinct from those of other noncompetitive nmda antagonists or of glutamate and glycine .
C0006864
cannabinoid
C0039663
tetrahydrocannabinol