thus , it is suggested that the increases in pra , prc and rrc in the captopril rats may be related to both the blood pressure reduction and interruption of the negative feedback inhibition of renin synthesis and release by aii , and that the decrease in prs in the captopril rats is due to the increased consumption and probably to the decreased rate of substrate production in the liver which is secondary to the decrease in plasma aii .
C0020649
blood pressure reduction
C0006938
captopril