these data suggest that stage 23 to 24 mesenchyme cells undergo normal chondrogenic maturation in culture in the presence of xylosides even though ( a ) most of the polysaccharides are synthesized onto the exogenously supplied xyloside substrate and released into the medium , ( b ) the proteoglycans that are synthesized are greatly reduced in polysaccharide content , and ( c ) the extracellular matrix as a consequence is greatly depleted in chondroitin sulfate content and , therefore , is abnormal in general morphology .
C0033692
proteoglycans
C0015350
extracellular matrix