the fetus was diagnosed as having i-cell disease based on the findings that ( 1 ) lysosomal enzyme activities except for acid phosphatase and alpha glucosidase were clearly elevated in amniotic fluid and were reduced in cultivated amniotic fluid cells , and ( 2 ) cytoplasmic inclusions were seen in cultivated amniotic cells by phase contrast microscopy .
C0205708
cytoplasmic inclusions
C0007634
cells