it has an overall efficacy comparable with amitriptyline and imipramine in depressive illness , but at dosages which have achieved a similar overall clinical improvement , mianserin causes significantly fewer anticholinergic side effects than amitriptyline or imipramine and also appears less likely than these drugs to cause serious cardiotoxicity on overdosage .
C0011581
depressive illness
C0020934
imipramine