to examine the nephrotoxicity of prolonged gentamicin administration compared to the effect obtained when a less toxic aminoglycoside is substituted during the course of treatment , we gave gentamicin ( 67.5 mg/kg per day ) to rats for 21 days , gentamicin for 14 days followed by either netilmicin or tobramycin for 7 days , or gentamicin for 14 days followed by saline diluent .
C0002556
aminoglycoside
C0027780
netilmicin