glucose loading of the tumor-bearing rats rendered the foot tumors physically more easy to heat ( due to inhibition of tumor blood flow ) , but combined hyperthermia and hyperglycemia lead to a decrease in survival rate ( 13 % compared to 41 % with heat alone ) , most animals died with widespread metastases in lymph nodes , lungs and kidneys .
C0017725
glucose
C0020456
hyperglycemia