various amounts of thyroglobulin ( 5-500 micrograms ) were used to immunize low ( dba/2 and c57bl/6 ) and high ( akr ) responder mice to observe the possible role of different thyroglobulin epitopes ( or of their density ) on the development of thyroiditis , to determine whether the h-2 control is observed for various amounts of antigen , and to find the optimum amount of thyroglobulin which best shows the genetic control of this disease .
C0003316
epitopes
C0003320
antigen