in the presence of dmpc , thermal denaturation could be measured for apo a-i above 70-75 `` '' c and for apo a-i1 and apo c above about 45 oc . in general , the denaturations were biphasic reactions for all apolipoproteins tested , with only a third , minor intermediate phase for apo a-i/dmpc denaturation . the two major kinetic phases are identified as an unfolding reaction of the apolipoprotein bound to the complex followed by a desorption step.the relaxation times ( tau ) associated with the latter step are dependent on the molecular weight of the apoprotein : when the temperature is increased from 70 to 90 oc , tau decreases from 400 to 1 min for apo a-i , while for apo a-i1 and apoc as the temperature is increased from 50 to 70 oc , tau decreases from 15 to l min .
C0003591
apolipoprotei
C0003594
apo