the influence of paromomycin on the activity of ribosomal suppressors has at least two aspects : ( 1 ) the drug increases translational ambiguity in sup1 and sup2 mutants in vitro and ( 2 ) it induces the alteration ( extension or restriction ) of sup 1 or sup2 suppression spectra in vivo .
C0035553
ribosomal
C1519614
translational