transport of acid phosphatase into lysosomes was sensitive to nh4cl and dependent on mannose 6-phosphate specific receptors by the following criteria : ( i ) inhibition of endocytosis of acid phosphatase by mannose 6-phosphate , ( ii ) enhancement of the secretion of acid phosphatase in the presence of antibodies to the mannose 6-phosphatase specific receptor , and ( iii ) secretion of about two-thirds of newly synthesized acid phosphatase in i-cell fibroblasts .
C0007634
cell
C0016030
fibroblasts