incubation of the neutral metalloendopeptidase thermolysin at ph 9-10 in the presence of 10 mm cacl2 for 2 days at room temperature with subtilisin at a 50:1 molar ratio leads to a derivative possessing lower ( approximately 3 % ) but intrinsic catalytic activity .
C1442934
metalloendopeptidase
C0039815
thermolysin