when compared to lean , nondiabetic db+/m+ or m+/m+ mice , db+/db+ mice demonstrated markedly altered in vivo immune responses characterized by a significantly diminished ability to reject allogeneic skin grafts , a markedly diminished capacity to generate cytotoxic cells after sensitization with allogeneic el-4 lymphoma cells and a significantly enhanced plaque-forming cell response to sheep erythrocytes .
C3485979
allogeneic
C0007634
cell