the proteolytic activity was identified as an elastase by the following criteria : 1 ) capacity to hydrolyze the synthetic substrate methoxysuccinyl-ala-ala-pro-val-4-methylcoumaryl-7-amide known to be specific for the pmn elastase , 2 ) pattern of apo-b proteolysis identical to that exhibited by pure pmn elastase , 3 ) inhibition of the proteolysis by the elastase inhibitor methoxysuccinyl-ala-ala-pro-val-ch2cl , 4 ) identity in molecular weight ( 28,000-30,000 ) of this activity with a pure preparation of pmn elastase labeled with [ 3h ] diisopropylfluorophosphate .
C0030306
elastase
C0064833
pmn elastase