32 patients with stable angina pectoris who had been receiving a controlled-release formulation durules of isosorbide 5-mononitrate ( imdur ) 60 to 120 mg daily with concomitant beta-blocker therapy for at least 1 year were entered into a study to evaluate possible rebound phenomena from the abrupt withdrawal of isosorbide 5-mononitrate and to determine whether nitrate tolerance had developed .
C0064079
isosorbide 5-mononitrate
C0028125
nitrate