a model depicting possible relationships between ligand binding sites on brain hexokinase , and how their interactions might lead to observed regulatory properties , is developed based on these and previous studies of ligand binding as well as evidence that mammalian hexokinases ( mr 100,000 ) have evolved by duplication and fusion of a gene coding for an ancestral hexokinase with mr 50,000 and which , like the mammalian enzyme , was sensitive to inhibition by glc-6-p .
C1517880
ligand binding
C1417249
mr