a review of the progress of 176 patients with parkinson 's disease who were given maximum tolerated doses of l-dopa between november , 1969 , and december , 1972 , showed that the ratio of observed to expected deaths after 12 years ' sustained therapy was 2.59 ( 2.14 for males and 3.64 for females ) .
C0030567
parkinson 's disease
C0023570
l-dopa