thirteen patients with severe rosacea ( rosacea papulopustolosa , rosacea conglobata , and rhinophyma ) were treated orally with 0.05 , 0.5 , or 1.0 mg/kg body weight 13-cis-retinoic acid ( isotretinoin , ro 4-3780 ) for 12-28 weeks .
C0035854
rosacea
C0035466
rhinophyma