in the anaesthetised guinea pig , eprozinol ( 5 mge . kg-1 ) , isoprenaline ( 2 micrograms . kg-1 ) and theophylline ( 15 mg . kg-1 ) administered intravenously cause a clear inhibition of the bronchospasm induced by intravenous perfusion of histamine or serotonin , with an intensity not significantly different for all three compounds .
C0039771
theophylline
C0006266
bronchospasm