as a preliminary step in evaluating the use of thyrotropin releasing hormone ( trh ) linked to toxin fragments for systemic treatment of pituitary disease , we have examined the metabolic degradation , tissue distribution , renal excretion , and toxicity in rats of trh-crm45 which consists of trh coupled to crm45 , a diphtheria toxin-related polypeptide .
C0032002
of pituitary disease
C0040162
trh