in the cultured in vitro human blood lymphocytes treated with 5-bromodeoxycytidine ( brdc ) plus thymidine ( dt ) in concentrations of 0.05 mm and 0.4 mm , respectively , metaphases of the second division , containing chromosomes with differentially stained sister chromatids appear after a 30 hours treatment , attaining 85 per cent at 36 hours .
C0008633
chromosomes
C1519334
sister chromatids