it is established that the preparation k-2-9 being administered in combination with cis-dichlorodiaminoplatinum ( ddp ) lowers the ddp toxic effects , in particular nephrotoxicity and enterotoxicity , increases the activity of the enzymes participating in microsomal liver oxidation , the activity of kidney transamidinase , the quantity of sh-groups of the liver and kidney tissue , intensifies the antitumour effect of ddp .
C0022646
kidney
C1514845
kidney tissue