in the current studies , inhibition of poly ( adp-ribose ) polymerase by 3-aminobenzamide , nicotinamide , or theophylline in cells exposed to lethal concentrations of h2o2 prevented the sequence of events that eventually led to cell lysis -- i.e. , the decrease in nad , followed by depletion of atp , influx of extracellular ca2+ , actin polymerization and , finally , cell death .
C0007634
cell
C0007587
cell death