therefore , we incubated adult rat hepatocytes on a laminin-rich matrix , matrigel , a new system that permits hepatocytes to respond to xenobiotics with induction of the microsomal hemoproteins , the cytochromes p-450 , in culture as they do in the intact liver ( schuetz , e. g. , li , d. , omiecinski , c. j. , muller-eberhard , u. , kleinman , h. k. , elswick , b. , and guzelian , p. s. ( 1988 ) j. cell . physiol . 134 , 309-323 ) .
C0018974
hemoproteins
C0010762
cytochromes p-450