in contrast , the vasodilator nitroprusside , in a dose causing an increase in blood flow equal to that of pge2 and pgi2 , potentiated both the histamine-induced plasma leakage , as well as the plasma and leukocyte extravasation after antigen challenge , indicating that the anti-inflammatory actions of the prostaglandins were unrelated to their vasodilator properties per se .
C0012472
pge2
C0033554
prostaglandins