the activity is primarily due to ornithine decarboxylase ( odc ) as evidenced by several criteria : the concurrent production of equimolar amounts of co2 and putrescine , the sensitivity of the reaction to difluoromethylornithine ( dfmo ) , a specific inhibitor of odc , the lack of major effect of two inhibitors of ornithine-2-oxo-acid transaminase , upon the dfmo-sensitive component of decarboxylation , the failure to profoundly reduce decarboxylation activity in the presence of a large excess of many aminoacids which could compete for non-specific decarboxylases .
C0029282
ornithine
C0007054
decarboxylases