the polyamine biosynthesis inhibitor alpha-difluoromethylornithine ( dfmo ) has been shown to potentiate the cytotoxicity of 1,3-bis ( 2-chloroethyl ) -1-nitrosourea ( bcnu ) in 9l rat brain tumor cells and in non-central nervous system human cancer cells in vitro , but the effects on a human brain tumor cell line have not been reported .
C0007257
bcnu
C0006118
human brain tumor