the density of total beta-adrenoceptors ( defined with isoprenaline ) and of beta 1- and beta 2-adrenoceptors ( defined with cgp 20712a and ici 118,551 respectively ) was studied by saturation binding of both radioligands in 13 brain areas . beta-adrenoceptor density was higher in caudate , putamen and nucleus accumbens ( 100-120 fmol/mg protein ) than cortex ( 50-70 fmol/mg protein ) and densities were lowest in hypothalamus and cerebellum ( 27-38 fmol/mg protein ) .
C0006104
brain
C0028633
nucleus