under the electron microscope i ) apparently all the cells forming rosettes or reacting with the gold-labeled anti-fcrii mab ( cikm5 or the f ( ab ) fragment of iv.3 ) contained birbeck granules and ii ) the gold-labeled mab were internalized in unfixed langerhans cells by receptor-mediated endocytosis and accumulated in lysosomes .
C0007634
cells
C0230694
birbeck granules