to further elucidate the site of action of opioids on the pituitary-adrenal axis , we studied the effect of d-ala2 , mephe4 , met- ( o ) enkephalin-ol ( sandoz , fk 33-824 ) on plasma acth and beta-endorphin immunoreactivity and serum cortisol in 7 normal subjects and 11 patients with cushing 's syndrome ( cushing 's disease , n = 7 ; adrenal adenoma , n = 2 ; ectopic cushing 's syndrome , n = 2 ) after administration of human corticotropin-releasing hormone ( hcrh ) .
C0001622
cushing 's disease
C0010481
cushing 's syndrome