in the mouse chloroform-induced ventricular fibrillation model and in the guinea pig ouabain-induced arrhythmia model , drugs of classes i ( amefalone , aprindine , lidocaine , mexiletine , phenytoin , procainamide , or quinidine ) , ii ( metoprolol or propranolol ) , and iv ( bepridil ) were active .
C0042510
ventricular fibrillation
C0025859
metoprolol