following electrothermic lesion , hepatic steroid metabolism in male rats was generally `` '' feminized '' '' ( increased 5alpha-reduction and decreased 6beta- and 16alpha-hydroxylation of 4-androstene-3,17-dione , decreased 2alpha- , 2beta- , 18- and 7beta-hydroxylation of 5alpha-androstane-3alpha , 17beta-diol and induced 15beta-hydroxylation of 5alpha-androstane-3alpha,17beta-diol,3,17-disulfate ) , whereas hepatic metabolism in female rats remained essentially unchanged .
C0038317
steroid
C0002854
a-androsta