phenobarbitone ( pb ) , 3-methylcholanthrene ( mc ) , aroclor 1254 ( aro ) , isosafrole ( iso ) and skf-525a each induced preferentially the o-dealkylation of different members of the homologous series , resulting in the appearance of 5 different sar plots , which characterized and differentiated between the 5 different inducers . beta-napthoflavone ( bnf ) had a similar effect to mc , whereas pregnenolone 16 alpha-carbonitrile treatment caused no large change in the metabolism of any of the substrates tested .
C1366496
aro
C0025519
metabolism