we describe a mutant of chinese hamster ovary cells which is resistant to elevated levels of alpha-methylornithine and alpha-difluoromethylornithine , reversible and enzyme-activated irreversible inhibitors , respectively , of the enzyme ornithine decarboxylase ( odc ) .
C0002260
alpha-difluoromethylornithine
C0029282
ornithine decarboxylase