il-1 induction of endothelial adhesivity was concentration dependent ( maximum , 10 u/ml ) , time dependent ( peak , 4-6 h ) , and reversible , was blocked by cycloheximide ( 10 micrograms/ml ) or actinomycin d ( 5 micrograms/ml ) but not by acetylsalicylic acid ( 100 microm ) , and occurred without detectable endothelial cell damage .
C0014257
endothelial
C0225336
endothelial