( 1 ) in 24,089 autopsy records from 1956 to 1979 we found in 16,653 corpses without gallstones 495 = 2.97 % , and in 7,436 corpses with gallstones 266 = 3.57 % colorectal cancers. -- ( 2 ) in 503 corpses with previous cholecystectomy performed more than one year before death we found 17 = 3.38 % colorectal cancers. -- ( 3 ) there is no higher incidence of colorectal cancer after cholecystectomy. -- ( 4 ) in the corpses with gallstones , cholecystectomy or cirrhosis of the gallbladder there were significantly more cancers in the right hemicolon than in corpses without gallstones. -- ( 5 ) a synetiology by genetic , epidemiologic or ( and ) metabolic factors may be possible. -- ( 6 ) a co-influence of primary bile acids on the genesis of colorectal cancer is discussed. -- ( 7 ) in patients over 50 years with gallstones it is mandatory for the surgeon to exclude a co-existing colorectal cancer before performing cholecystectomy .
C0016976
gallbladder
C0008320
cholecystectomy