the increase in type iv collagenase was found to be specific for laminin because another cell-binding matrix protein , fibronectin , did not have any effect , and epidermal growth factor and transferrin actually decreased the type iv collagenase in human melanoma culture medium ( epidermal growth factor , 50 % at 20 ng/ml ; and transferrin , 20 % at 10 micrograms/ml ) .
C0086418
human
C0242275
epidermal growth