we conclude that surgical closure of the symptomatic patent ductus arteriosus in neonates is safe and 100 % effective , with none of the reported complications of indomethacin therapy , and should be the treatment of choice in neonates aged less than 33 weeks ( gestational age ) at birth with symptomatic patent ductus arteriosus .
C0021246
indomethacin
C0013274
patent ductus arteriosus