in vitro , polymerization of tubulin isolated from porcine brains was completely inhibited at a 1 x 10 ( -5 ) m concentration of rhizoxin , and tubulin which had been polymerized by incubation at 37 degrees c for 30 minutes was depolymerized by addition of 1 x 10 ( -5 ) m of the drug .
C0006104
brains
C0086045
concentration