a 1-year follow-up study of the t-cell subset abnormalities was carried out in 16 severe haemophilia a patients , treated `` '' on demand '' '' with an average amount of 500 u/kg/yr of factor viii concentrate ( group a ) and in 15 mild haemophiliacs or von willebrand patients treated only sporadically with less than 3000 u of factor viii and no longer exposed to any other blood component in the 2 years preceding the beginning of the study ( group b ) .
C0042974
von willebra
C0015506
factor vi