it is concluded that conventional chemotherapy is unlikely to be effective in children with acute lymphoblastic leukaemia who relapse soon after stopping treatment , that `` '' reprophylaxis '' '' of the central nervous system probably with long-term intrathecal chemotherapy is essential , and that some patients relapsing after prolonged unmaintained remission may achieve long-term leukaemia-free survival .
C0023449
acute
C0023418
a-fr