recent studies of platelet-derived growth factor ( pdgf ) have revealed several structural and functional similarities between this growth factor or components linked to its mechanism of action and certain oncogene products : pdgf itself has a structural homology with the transforming protein of simian sarcoma virus , the pdgf receptor has a functional homology ( tyrosine kinase activity ) with a family of oncogene products , and pdgf induces the expression of the cellular counterparts of myc and fos .
C0018284
growth factor
C0032200
pdgf