at doses that caused a comparable degree of alpha 1-adrenergic receptor blockade , ketanserin ( 0.1 , 0.3 , and 1.0 mg/kg i.v . ) as well as prazosin ( 0.01 , 0.03 , and 0.10 mg/kg i.v . ) decreased the blood pressure as a result of a reduction in total peripheral resistance .
C0032912
prazosin
C0020649
blood pressure