because immunization with dinucleotides coupled to protein prepared by the same method we have used , yields higher specificity to the base attached to the carrier protein , our findings suggest that , in scleroderma , a single event , akin to that of immunization with a purified antigen , gives rise to the anti-rna antibodies , whereas in systemic lupus erythematosus there is a considerably wider immunological aberration .
C0033684
protein
C0007292
carrier