to ascertain whether the absence of immunocytochemically detectable gst-p and ggt proteins in peroxisome proliferator-induced neoplastic lesions is due to the absence of specific mrnas , we analyzed the total rna isolated from hepatocellular carcinomas induced by three different peroxisome proliferators ( ciprofibrate , wy-14643 , and br-931 ) and the genotoxic carcinogens , 2-acetylaminofluorene and aflatoxin b1 ( afb ) , for the presence of gst-p , ggt , and alpha-fetoprotein ( afp ) mrnas .
C2239176
hepatocellular carcinomas
C0002210
alpha-fetoprotein