isosorbide dinitrate increased the cardiac output during exercise from 4.6 +/- 0.9 liter/min to 5.3 +/- 0.8 liter/min ( p less than 0.01 ) but also did not change exercise vo2 ( control , 488 +/- 62 ml/min ; isosorbide , 473 +/- 44 ml/min ) , peak lactate concentration ( control , 19.2 +/- 6.0 mg/dl ; isosorbide , 21.4 +/- 8.2 mg/dl ) or oxygen debt ( control , 522 +/- 154 ml ; isosorbide , 445 +/- 147 ml ) ( all p less than 0.10 ) .
C0022252
isosorbide dinitrate
C0022251
isosorbide