five of the eight loci ( tgfb-1 , bmp-2a , bmp-2b1 , bmp-2b2 , vgr-1 ) mapped near mutant loci associated with connective tissue and skeletal disorders , raising the possibility that at least some of these mutations result from defects in tgf-beta-related genes .
C0527443
bmp-2a
C0053932
bmp