vmax of the action potential upstroke in canine cardiac purkinje fibers was studied in the presence of seven class i antiarrhythmic drugs -- lidocaine ( 4 micrograms/ml ) , mexiletine ( 4 micrograms/ml ) , propranolol ( 0.9 micrograms/ml ) , procainamide ( 30 micrograms/ml ) , quinidine ( 5 micrograms/ml ) , flecainide ( 4 micrograms/ml ) , and disopyramide ( 3.1 micrograms/ml ) -- at constant cycle lengths ( ccl ) and after abrupt changes in cycle length ( accl ) .
C0003195
antiarrhythmic
C0012702
disopyramide