it has been shown that bicuculline -- gaba-ergic receptors specific blocking agent in doses of 0.5 and 1.0 mg/kg ( subcutaneously ) , and thiosemicarbazide ( inhibiting the brain gaba synthesis ) in dose of 5.0 and 8.0 mg/kg ( subcutaneously ) were capable of antagonizing diazepam effects and of reducing its tranquilizing activity in an experimental test of conflict behavior in rats .
C0233660
blocking
C0006104
brain