in contrast , the solvent isotope effect on the vmax for the horseradish peroxidase catalyzed demethylation reaction was approximately 1.5 with either ethyl hydroperoxide or hydrogen peroxide as the oxidant , indicating that the exchange of hydrogens in the enzyme and hydroperoxide for deuterium in d2o has little effect on the rate of the demethylation reaction .
C0020275
hydrogens
C0011744
deuterium