the metabolic fate of alkyl homologs ( alkyl=methyl , ethyl , propyl , pentyl , and tert-butyl ) of n-butyl-n- ( 4-hydroxybutyl ) nitrosamine ( bbn ) , a potent bladder carcinogen , was investigated in the rat , in order to elucidate any possible correlation of structure and metabolism with organospecific carcinogenicity to the urinary bladder of these n-nitrosamines .
C0007090
carcinogen
C1516272
metabolism