our results indicate that , in the management of pyelonephritis complicating preexisting renal disease , if the minimal inhibitory gentamicin concentration for an infecting organism is greater than the usual therapeutic an nontoxic serum levels of the compound , then it may be appropriate to use alternate antibiotics that demonstrate lesser reduction in tissue drug accumulation in diseased kidneys .
C0022658
renal disease
C0022646
kidneys