at equieffective anti-inflammatory doses in the rat , etodolac ( 3 mg/kg/day ) did not significantly lower the concentrations of either pge2 or 6-keto-pgf1 alpha , whereas both 3 mg/kg/day of naproxen and 300 mg/kg/day of aspirin significantly lowered the concentrations of both prostaglandins .
C0012472
pge2
C0033554
prostaglandins