the combined data from histone h1/h5 binding and histone h1 methylation studies suggest that upon addition of exogenous histone h5 to rat liver nuclei the binding of two lysine-rich histones per nucleosome plays a significant role in the induction of specific changes in chromatin structure , which in vivo may have important functional implications in terms of chromatin condensation and suppression of transcription .
C0019644
histone h1
C0007610
nuclei