a number of carbamoyl- and n ( 1 ) -substituted analogs of physostigmine were synthesized and their in vitro potencies ( ic50 values ) vs. human erythrocyte and brain ( cerebral cortex and caudate nucleus ) acetylcholinesterase ( ache ) and electric eel ache and against human brain and plasma butyrylcholinesterase ( bche ) were compared to the potencies of physostigmine and other traditional anticholinesterases .
C0007461
caudate nucleus
C0006104
brain