the mutational basis of cancer is supported by the clonal nature of tumors , the mutagenicity of most carcinogens , high mutation frequencies in cells of cancer-prone human fibroblasts lacking dna repair enzymes , the correlation of in vitro dna damage and in vitro mutation and transformation frequencies with in vivo tumorigenesis , age-related incidences of various hereditary tumors , and the correlation between photoreactivation of dna damage and the biological amelioration of uv-induced neoplasms .
C0006826
cancer
C0027651
neoplasms