mannitol also significantly lessened the s-t segment elevation ( epicardial electrocardiogram ) occurring during myocardial ischemia in the isovolumic hearts and this reduction was associated with significant increases in total coronary blood flow ( p < 0.005 ) and with increased collateral coronary blood flow to the ischemia area ( p < 0.005 ) .thus , increases in serum osmolality produced by mannitol result in the following beneficial changes during myocardial ischemia : ( a ) improved myocardial function , ( b ) reduced s-t segment elevation , ( c ) increased total coronary blood flow , and ( d ) increased collateral coronary blood flow .
C0018787
hearts
C0027061
myocardial