e-induced stimulation of pituitary-adrenal activity is mediated by beta adrenoceptors and involves release of crf , because it can be prevented by beta-adrenoceptor blockers and by destruction of crf neurons ( hypothalamic lesions ) , blockade of crf release ( chlorpromazine , morphine , and nembutal ) , or administration of crf antiserum .
C0020663
hypothalamic
C0010132
crf