in the presence of indomethacin , the negative chronotropic effects of both atp and adenosine ( 3 mumol/kg each ) were significantly augmented to a similar extent , proportionally : the maximal percent increase in sinus rhythm cycle length following atp increased from 203 +/- 33 to 266 +/- 62 ms ( p less than 0.025 ) , and following adenosine increased from 44 +/- 8 to 64 +/- 20 ms ( p less than 0.001 ) .
C0001480
atp
C0001443
adenosine