it is concluded that the brain extracellular bicarbonate concentration in respiratory acidosis increases because the h+ formed from the hydrated co2 reacts with the intracellular buffers of brain cells , mainly glial cells , and hco-3 inside the cell is formed and exchanged for cl- outside the cell similar to the hco-3/cl- exchange which occurs between red cells and blood plasma during co2 loading .
C0006104
brain
C0086045
concentration