although in a majority of eyes with stage 1 changes there is a progression to hole formation , spontaneous separation of the vitreous without hole formation may occur in some cases ( 44 % ) and cause characteristic biomicroscopic changes , including foveal reattachment , disappearance of the yellow spot or ring , and , in some cases , a pseudo-operculum , with one or more lamellar holes or facets .
C0015392
eyes
C0042907
separation