the incidence of potentially serious drug-related elevations of bun or serum creatinine was examined among 1468 patients with rheumatoid arthritis or osteoarthritis who took daily therapeutic doses of aspirin , ibuprofen , or oxaprozin , an investigational nonsteroidal antiinflammatory drug ( nsaid ) , in multicenter clinical trials .
C0029408
osteoarthritis
C0004057
aspirin