meister and co-workers ( manning , j. m. , moore , s. , rowe , w. b. , and meister , a . ( 1969 ) biochemistry 8 , 2681-2685 ) have shown that l-methionine-s-sulfoximine , one of the four diastereomers of methionine sulfoximine , preferentially inhibits glutamine synthetase irreversibly in the presence of atp , due to the formation of tightly bound products , adp , and methionine sulfoximine phosphate .
C0025646
l-methionine
C0025649
methionine sulfoximine