the chromatography procedure separated factor xa from factor x , the russel 's viper venom proteinase used to activate factor x , and traces of contaminating thrombin . alpha-factor xa was unstable at ph 7.6 and 25 degrees c , undergoing slow proteolytic degradation to functionally heterogeneous products as evidenced by the greater loss of coagulation assay activity compared to activity measured with a chromogenic substrate .
C0030946
proteinase
C0597304
proteolytic