in temperature studies , below 47 degrees c , the decrease in the activation rate was not related to the thermal denaturation of enzyme or substrate , nor to the choice of activator enzyme ( factor xiia or kallikrein ) , nor to the species of factor xii ( human or bovine ) but to a behavior , designated a thermal transition , associated with the surface or the protein-surface interaction .
C0015527
factor xiia
C0015525
factor xii