at the peak of the response , 10 -- 18 days p.o. , reacting neurones showed nucleolar condensation and vacuolation , the appearance of intranuclear electron-dense particles , extensive accumulation of intracytoplasmic lipid droplets , increased numbers of microtubules and neurofilaments , focal mitochondrial aggregates , and widespread mitochondrial degeneration .
C0027882
neurones
C0027834
neurofilaments