these sites bound the radioligand in a reversible manner at low temperature ( less than 2 degrees c ) but irreversibly at temperatures between 6 and 24 degrees c , properties characteristic of the activation of the enzyme by treatment with gmp.p ( nh ) p described previously ( krall , j. f. , leshon , s. c. , frolich , m. , and korenman , s. g. ( 1981 ) j. biol . chem . 256 , 5436-5442 ) .
C0039476
temperatures
C1521970
characteristic