tunicamycin , an inhibitor of dolichol-diphospho-n-acetylglucosamine formation and hence an inhibitor of n-linked oligosaccharide biosynthesis , suppressed total proteoglycan synthesis by swarm rat chondrosarcoma chondrocytes without affecting the size of the proteoglycan molecule , its secretion from the cell , or its ability to be retained in the extracellular matrix .
C0033692
proteoglycan
C0015350
extracellular matrix