they include : development of a micromethod for determining drugs in biological objects , estimation of drug stability in biological objects on storage , evaluation of drug distribution coefficients , investigation of drug solubility rate , drug binding to plasma proteins and erythrocytes , studying of drug metabolism in vitro and in vivo , investigation of drug kinetics in test tissues after single and repeated administrations , estimation of drug bioavailability , investigation of drug excretion and distribution in organs and tissues , determination of concentration-effect relationships in test tissues and studying of drug pharmacokinetics in models simulating pathological processes .
C0025519
metabolism
C0221102
excretion