the ligand binding at l site shows the apparent dissociation constant ( kd ) of 1 to 3 x 10 ( -6 ) m and total binding sites ( bt ) of 6 to 8 x 10 ( 7 ) /cell , represents approximately 85 % of the total saturable binding , displays a broad specificity interacting with cytochalasins c , d , and e , is not displaceable by d-glucose , is located mostly in a cytosol fraction , and exists in intimate relation to cytoskeletal actin .
C0007634
cell
C1383501
cytosol