acetylation of nucleosomal core histones is thought to be one of the factors regulating transcriptional activity of chromatin , and it is suggested that this reaction negatively regulates thyroid hormone receptor levels in gh1 cells ( samuels , h.h. , stanley , f. , casanova , j. , and shao , t. c. j. biol . chem . 255 , 2499-2508 ) .
C1518457
nucleosomal core
C0007634
cells