the evidence for this is that 1 ) the rate of accumulation of [ 3h ] inositol 1-phosphate is linear for up to 90 min in the presence of carbachol , 2 ) pretreatment of cells with 100 microm carbachol for 75 min does not diminish the subsequent ability of carbachol to increase [ 3h ] inositol 1-phosphate accumulation , and 3 ) the production of all of the [ 3h ] inositol phosphates including the polyphosphoinositide metabolites [ 3h ] inositol bis- and trisphosphate continues for up to 75 min in the presence of carbachol and declines rapidly when the muscarinic receptor antagonist atropine is added .
C0021554
inositol phosphates
C0021547
inositol