the antiarrhythmic effects of mexiletine ( n = 14 ) were compared to procainamide ( n = 16 ) by a double-blind parallel protocol in 30 patients ( group i ) with frequent premature ventricular contractions ( pvcs ) ( greater than 20/hr ) , and to amiodarone by an open-label sequential approach in 25 patients ( mean left ventricular ejection fraction of 32.6 +/- 13.4 % ) with life-threatening ventricular arrhythmias ( group ii ) resistant to two or more conventional agents .
C0025887
mexiletine
C0151636
premature ventricular contractions