24,25-dhcc increased intestinal absorption of calcium equally well in anephric patients , suggesting that conversion of 24,25-dhcc to 1,24,25-trihydroxycholecalciferol by the kidney can not be the sole mechanism by which 24,25-dhcc expresses biological activity , even though in vitamin d deficient rats nephrectomy does abolish the ability of large doses of 24,25-dhcc to increase calcium absorption .
C0022646
kidney
C0027695
nephrectomy