studies on its toxicity and action in avian and simian malaria show that its chronic toxicity in monkeys is similar to that of the established antimalarials and that it lacks causal prophylactic , gametocidal and sporontocidal activity against plasmodium gallinaceum.dds is also inferior to the established antimalarials in its schizontocidal activity against p. gallinaceum , while against p. knowlesi its activity is of the same order as that of proguanil and against p. cynomolgi it is more effective than quinine , mepacrine , pyrimethamine , chloroquine and proguanil but less effective than sulfadiazine .
C0034283
pyrimethamine
C0008241
proguanil