in order to evaluate the role of histamine as a possible mediator of the acth-cortisol response to naloxone , a specific opioid receptor antagonist , 12 normal men were treated with naloxone before and after the administration of dexchlorpheniramine and cimetidine , respectively h1 and h2 histamine receptor antagonists .
C0008783
cimetidine
C2757005
h2