that the factor conferring ecac-c specificity was immunoglobulin was demonstrated by the retention of ecac-c-specific reactivity of patient sera in the presence of normal peripheral blood mononuclear cells , the ability of patient sera ( without cells ) to effect complement-mediated lysis against erythrocytes labeled with ecac-c ( 8.0 +/- 6.7 % ) but not with control kidney antigen ( 0.7 +/- 0.7 % ) , and the fact that purified immunoglobulin from patient sera could substitute for the latter in an ecac-c-specific antibody-dependent cellular cytotoxicity assay .
C0229671
sera
C0009498
complement