within this cephalosporin series , analogs ( 9f approximately 13f ) with 2-hydroxyimino-2- ( 3-hydroxyphenyl ) acetyl group at the 7-position of a cephem nucleus were found to have the highest antibacterial activity against a wide-range of microorganisms , including beta-lactamase-producing bacteria .
C0597979
beta-lactamase
C0004611
bacteria