ca2+ ( 10 microm ) , cyclic amp ( 100 microm ) and a protein kinase c-activating phorbol ester , phorbol 13-myristate 12-acetate ( pma ; 100 nm ) produced marked changes in the phosphorylation state of a number of proteins in permeabilized islets after incubation for 1 min at 37 degrees c .
C0031586
phorbol
C0039654
pma