having crossed the bbb , the activated t-cells interact with local glial cells by releasing factors , including interferon-gamma , which induced astrocytes to synthesize and express , on their membranes , class ii major histocompatibility antigens ( ia determinants ) , which are critically required for immunogenic presentation of antigens to t-cells .
C0019630
class ii major histocompatibility antigens
C0206431
presentation