we now show that the apo-alpha 2 beta 2 complex of tryptophan synthase will bind two unnatural substrates , pyridoxamine phosphate and indole-3-pyruvic acid , and will convert them by a single-turnover , half-transamination reaction to pyridoxal phosphate and l-tryptophan , the natural coenzyme and a natural product , respectively .
C0034266
pyridoxal phosphate
C0009235
coenzyme