since the gene for esterase d ( esd ) is known to be tightly linked to the retinoblastoma locus ( rb1 ) in the q14.1 band of chromosome 13 , we have cloned the esd gene from a human cdna library by using oligonucleotides specific for a partial amino acid sequence of the purified enzyme to provide a genetic marker for further studies on retinoblastoma .
C0080113
rb1
C0035335
retinoblastoma