selection in long-term culture of alloreactive t cells , by successive in vitro restimulation with semi-allogeneic cells , results in primed responder cell populations which maintain full proliferative reactivity to allogeneic cells as well as to the t cell mitogens concanavalin a ( con a ) and phytohemagglutinin ( pha ) but are depleted of cells which can effect target cell destruction in either a specific or nonspecific manner .
C3485979
allogeneic cells
C0007634
cells