from these experiments we conclude that ( i ) c-myc , c-myb , and p53 are regulated independently at both the transcriptional and post-transcriptional levels , ( ii ) dfmo inhibits mel cell proliferation and expression of several genes , including c-myc , c-myb and p53 , and ( iii ) dfmo suppresses terminal differentiation but is unable to alter proto-oncogene changes associated with the early stages of differentiation .
C0596290
cell proliferation
C0086661
c-myc