we now demonstrate that this effect is triggered by the lipid a domain of lipopolysaccharide since a defined tetraacyl disaccharide 1,4'-bisphosphate precursor of mature lipid a , designated lipid iva ( raetz , c. r. h. , purcell , s. , meyer , m. v. , qureshi , n. , and takayama , k. ( 1985 ) j. biol . chem . 260 , 16080-16088 ) , is fully active in stimulating kappa chain mrna synthesis .
C0023810
lipopolysaccharide
C0023767
lipid a