the relative amount of dopa decarboxylase in this trapping mechanism as compared to the parenchyma per se was estimated in various cns regions , measuring the formation of dopamine from l-dopa in vitro or in vivo in two experimental models on rats and rabbits : ( 1 ) on the basis of the treatment with a peripheral decarboxylase inhibitor ( carbidopa , which inhibits also microvascular dopa decarboxylase in the cns ) it could be calculated that the enzyme in the microvessels of the caudate nucleus ( rich in catecholamine nerve terminals ) , cerebellum ( poor in catecholamine nerves ) , and spinal cord comprised 25 , 91 and 79 per cent , respectively , of the total enzyme activity .
C3714787
cns
C0037925
spinal cord