at 5 mg/kg ( 16.5 x 10 ( -6 ) mol/kg ) propranolol caused a small , but significant , increase in blood pressure in sham-operated sh rats , whereas both after 1 and 5 mg/kg ( 3.3 x 10 ( -6 ) and 16.5 x 10 ( -6 ) mol/kg ) immediate hypotension was observed in baroreceptor-denervated animals .
C0033497
propranolol
C0020649
hypotension