the islets were pulse labelled for 15 min with [ 3h ] leucine ( present in rat insulin i and ii ) or [ 35s ] methionine ( unique to rat insulin ii ) and then incubated for a 165 min post-label ( chase ) period during which the majority of labelled proinsulin was converted to insulin but under conditions whereby greater than 95 % of radiolabelled proinsulin or insulin was retained in the islets .
C0033362
proinsulin
C0021641
insulin