it was shown that laminin was located in the lamina densa of basement membranes ( bm ) in normal human tissue and visible on bm like structures around decidua cells , bm were abnormally thick and often multilayered but continuous and laminin positive in intraductal breast carcinomas and well differentiated follicular carcinomas of thyroid , in invasive carcinomas laminin immunostaining displayed an heterogeneous pattern with disruptions and even may completely disappeared , in tumor stroma , blood vessels bm had a laminin abnormal staining with a multilayered pattern .
C0022984
laminin
C0004799
bm