the elimination kinetics of theophylline were investigated following intravenous administration of aminophylline in 12 subjects ( six fit young , and six healthy hospitalised elderly volunteers ) at 09.00 h and 21.00 h on separate occasions at least 5 days apart to determine whether time of administration had significant effects on clearance in young and elderly subjects .
C0002575
aminophylline
C0036572
fit