these data indicate that ( 1 ) administration of antigens into inflamed lung results in an enhanced systemic immune response , ( 2 ) although larger quantities of soluble antigens administered by the pulmonary route accumulate in the hln when lungs are inflamed , cells from this tissue do not exhibit an enhanced pfc response , and ( 3 ) large doses of soluble antigens instilled into normal lungs induce a greater systemic immune response that the same doses administered i.v .
C0003320
antigens
C0301872
immune response