hydroxyproline analysis of bone explants and culture medium revealed a 1,25 ( oh ) 2d3-induced decrease in the 3h-hydroxyproline content of the system ( bone + medium ) , suggesting that the effect of 1,25 ( oh ) 2d3 is due to inhibition of collagen synthesis rather than enhanced collagen degradation , impaired incorporation of collagen into bone matrix , or bone resorption .
C0262950
bone
C0005962
bone matrix