these differences in enzyme localization imply that acetoacetate is converted into acetoacetyl-coa only by 3-oxo acid-coa transferase in the mitochondria and cytoplasm of the chick brain , whereas , in the rat brain , this reaction is performed by 3-oxo acid-coa transferase in mitochondria and by acetoacetyl-coa synthetase in the cytosol .
C0000988
acetoacetate
C0022618
oxo