[ 3h ] glutamate uptake into astrocytes in primary culture was potently inhibited by the aspartate analogues l- and d-aspartic acid , dl-threo-beta-hydroxy-aspartic acid-beta-hydroxymate ( ic50 's : 136 , 259 , 168 , and 560 microm , respectively ) and by beta-dl-methylene-aspartate , a suicide inhibitor of aspartate aminotransferase ( ic50 : 524 microm ) , and by the endogenous sulphur-containing amino acid l-cysteinesulfinic acid ( ic50 : 114 microm ) , [ 3h ] glutamate uptake was not significantly affected by either n-methyl-d-aspartate or dl-homocysteine thiolactone .
C0004015
aspartic acid
C0949752
beta