the location of reaction product coupled with ultrastructural alterations in the tissue suggests that pancreatic elastase instilled into the trachea may reach the interstitium in two ways : first , transport may take place across intact alveolar type i cells via pinocytotic vesicles , and second , a small amount of enzyme may gain access to the connective tissue after the disruption of epithelium in a few highly focal areas .
C0225699
alveolar type i cells
C0014609
epithelium