the cardiovascular effects produced by i.c.v . injection of the three sympathomimetic amines could be reproduced in cross-circulation experiments in the recipient dog when the amines were injected into its head circulation , and the effects of noradrenaline and phenylephrine , but not those of isoprenaline , were abolished by the alpha-adrenoceptor blocking agent yohimbine ( 1 mg/kg ) injected intravenously into the donor dog.5 .
C0007226
cardiovascular
C0005775
circulation