a simple model based on a known prominent structural feature , which is common to the trypsin family of serine proteases , two extensive coaxial halfcylinders of beta-sheets , to which previously no mechanistic function could be assigned , is proposed to account for the role of the attractor in the catalytic process : ( 1 ) control of the entry of a specific substrate to the catalytic site by co-ordinated disentanglement of the interlocking sidechains ;
C0041236
trypsin
C0036734
serine proteases