thirteen of 14 temperature-sensitive mutants deficient in successive steps of mitotic chromosome transmission ( cdc2 , 4 , 5 , 6 , 7 , 8 , 9 , 13 , 14 , 15 , 16 , 17 and 20 ) from spindle pole body separation to a late stage of nuclear division exhibited a dramatic increase in the frequency of chromosome loss and/or mitotic recombination when they were grown at their maximum permissive temperatures .
C1166688
mitotic chromosome
C1158501
mitotic