in early and moderate stages of disease there was polyantigenic expansion of all the intrinsic components of mesangium , glomerular basement membrane ( gbm ) , and tubular basement membrane ( tbm ) assessed by polyclonal antisera to collagen types iv and v , laminin , and by monoclonal antibodies to type iv collagen and fibronectin and to four other intrinsic components of normal renal extracellular matrices ( mbm10 , 11 , 12 , and 15 ) .
C0017655
mesangium
C0022646
renal