6-keto-pge1 is not extensively metabolised in the isolated perfused rat lung ( 20.4 or 4.2 % , depending on protocol ) , compared with pge1 ( 84.3 or 78.5 % ) , and is a much poorer substrate for the principal prostaglandin metabolising enzyme , prostaglandin 15-hydroxydehydrogenase .
C0002335
pge1
C0033554
prostaglandin