these data are contrasted with previous reports for chinese hamster lung fibroblasts that the increase in intracellular ph which results from activation of the na+/h+ antiporter in bicarbonate-free media is necessary for s6 phosphorylation , protein synthesis , and hence , for subsequent dna synthesis ( pouyssegur , j. , chambard , j. c. , franchi , a. , paris , s. , and van obberghen-schilling , e. ( 1982 ) proc . natl . acad . sci . u.s.a. 79 , 3935-3939 ; chambard , j.c. , and pouyssegur , j . ( 1986 ) exp . cell res . 164 , 282-294 ) .
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fibroblasts
C0007634
cell