based on this information , it is suggested that effectiveness of currently used topical fluoride treatments may be significantly increased by ( 1 ) including in the regimen a dicalcium-phosphate-dihydrate-forming treatment so that a portion of the labile fluoride is re-incorporated as tooth-bound fluoride , and ( 2 ) employing application methods which ensure the effective delivery of treatment agents to the fissures , and to approximal and cervical surfaces , where most caries occurs .
C0016327
fluoride
C0011334
caries