not only are host radiosensitive lymphocytes of systemic origin necessary for the manifestation of normal pln hypertrophy , but as few as 2.5 x 10 ( 6 ) parental lymph node cells ( lncs ) injected into the hind footpad of adult f1 hybrid rats disseminate widely , provoking significant systemic gvh reactions , as measured by splenomegaly , and distant lymphadenopathy .
C0020564
hypertrophy
C0038002
splenomegaly