due to increased fracture incidence as a result of osteoidosis observed under ethane-hydroxy diphosphomate ( ehdp ) administration , today amino-hydroxy-propylidine diphosphonate ( apd ) and dichloromethylene diphosphonate ( clodronate ) are preferred in the treatment of paget 's disease .
C0012544
diphosphonate
C0012081
dichloromethylene diphosphonate