investigated was the effect of various amino agents ( stained and phthalic anhydride and sulfopicric acid ) on the complement-and antigen-fixing activity of igg and igm antibodies isolated from guinea pig sera , the donor animals being hyperimmunzed with type o , strain polyana , of the foot-and-mouth disease virus , at the moderate modification ( 75-86 per cent acetylation , and 36-40 per cent 'phthalation ' ) of the primary amino groups the foot-and-mouth disease antibodies retained only half of the conjugation caused greater and complete loss of this activity .
C0009498
complement
C0229671
sera