blood pressure reduction induced by antihypertensive drugs with different mode of action approximated the pathological altered synthesis of txb2 in spontaneously hypertensive rats to values of normotensive rats : in the kidney medulla by all drugs used , in the aorta only by the most efficient drugs ( clonidine , dihydralazine ) and in plasma and serum only in connection with a reduction in heart rate ( clonidine , propranolol ) .
C0428977
reduction
C0033497
propranolol