the two oxidized metabolites of acyclovir , 9-carboxymethoxymethylguanine ( ki = 720 microm ) and 8-hydroxy-9- ( 2-hydroxyethoxymethyl ) guanine ( ki greater than 2000 microm ) , were less inhibitory than was the parent drug .
C0001367
acyclovir
C0018321
guanine