because the diabetic state in rats is associated with lowered t3 ( triiodothyronine ) and t4 levels and because diabetic patients excrete large amounts of myo-inositol , a lipotropic agent , we investigated the effects of myo-inositol and t3 on the elevated myocardial lipid levels and depressed cardiac performance of streptozocin ( 55 mg/kg i.v . ) -induced diabetic ( stz-d ) rats . myo-inositol ( 2.5 g.kg-1.day-1 in the drinking water ) and t3 ( 30 micrograms.kg-1.day-1 s.c. ) were given for an 8-wk period 3 days after diabetes induction .
C0027061
myocardial
C0018787
cardiac