to investigate in adult animals the distribution and differentiation of the synapses made by axotomized cns neurons whose regenerating axons are guided back to their natural targets in the brain , we attached an autologous peripheral nerve ( pn ) graft 2-3 cm in length to the ocular stump of a transected optic nerve ( on ) in adult hamsters , inserted the distal end of the graft into the superior colliculus ( sc ) , and , 6-8 weeks later , labeled the retinal ganglion cell ( rgc ) axons that entered the sc with hrp orthogradely transported from the eye .
C3714787
cns
C0006104
brain