in this study , 62 patients with confirmed initial normal renal function and treated with 2 to 5 mg/kg/day of gentamicin sulfate or tobramycin sulfate for a minimum of seven days were followed up prospectively for the development of aminoglycoside-related renal failure , defined as at least a one-third reduction in renal function .
C0027519
tobramycin sulfate
C0002556
aminoglycoside