in rats given 0-2,000 pmol 25 ( oh ) d3 chronically by mouth , there was a dose-dependent decline in the percent of serum radioactivity made up of 1,25-dihydroxy- [ 26,27-methyl-3h ] cholecalciferol [ 1,25 ( oh ) 2 [ 3h ] d3 ] as well as a decline in mitochondrial 1-hydroxylase , and these correlated significantly ( r = 0.83 , p less than 0.001 ) .
C2713074
25 ( oh ) d3
C0008318
cholecalciferol