men aged 40-64 years with mild to moderate hypertension [ diastolic blood pressure ( dbp ) 100-130 mmhg ] were randomized to treatment with a diuretic ( n = 3272 ) or a beta-blocker ( n = 3297 ) , with additional drugs if necessary , to determine whether a beta-blocker based treatment differs from thiazide diuretic based treatment with regard to the prevention of coronary heart disease ( chd ) events and death .
C0018799
the
C0018787
heart