the present study provides conclusive evidence for two central issues : that calcium is the first messenger for the prompt , plasma membrane-mediated action of thyroid hormone to increase cellular sugar uptake , and that thyroid hormone produces an acute increase in calcium uptake by the heart , an effect that is demonstrable at physiological concentrations and is thyroid hormone specific and , therefore , points to a physiological relevance for this action .
C0007603
plasma membrane
C0007634
cellular