since most studies on the regulation of the [ 3h ] imipramine binding sites by antidepressants have used desipramine displaceable binding , which is heterogenous in nature and contains binding not related to 5-ht uptake sites , the present report studies the possible effects of chronic ( 3 weeks ) administration of imipramine or norzimeldine ( 10 mg/kg intraperitoneally twice daily ) on 5-ht sensitive [ 3h ] imipramine binding sites .
C0003289
antidepressants
C0011685
desipramine