theophylline decreased the incidence of apnea ( p less than .05 ) , increased respiratory minute volume ( p less than 0.001 ) , decreased ( paco2 ( and paco2 p less than 0.001 ) , increased the slope of the co2 response curve ( p less than 0.02 ) with a significant shift to the left ( p less than 0.02 ) .
C0039771
theophylline
C0003578
apnea