a specific cross-desensitization occurred between gaba and ( - ) -baclofen.4 the bicuculline-insensitive relaxation induced by gaba and ( - ) -baclofen was prevented by tetrodotoxin and hyoscine but not by phentolamine plus propranolol , naloxone or theophylline.5 in preparations in which the muscle tone was raised by histamine or prostaglandin f ( 2alpha ) , gaba and ( - ) -baclofen induced relaxation to the same extent as before increasing the tone .
C0016904
gaba
C0004609
baclofen