accounting for histopathologic diagnosis , stage of disease , ploidy , and the proportion of tumor g1/100 cells , the following sequence of adverse prognostic factors in order of their relative ranks was established : ( 1 ) absence of breast cancer ( p=0.0001 ) , ( 2 ) hypertriploid dna index ( p=0.049 ) , and ( 3 ) presence of metastatic disease ( p=0.079 ) .
C0027651
tumor
C0006826
cancer