in a study of 16 men and 55 women with temporal lobe epilepsy ( tle ) , we found that the serum dehydroepiandrosterone sulfate ( dhea-s ) level was significantly lower ( p less than 0.05 ) in patients who were treated with phenytoin ( mean +/- sd dhea-s in men , 685 +/- 429 ng/ml ; in women , 580 +/- 289 ) , carbamazepine ( women , 779 +/- 529 ) , or a combination of the two drugs ( men , 491 +/- 246 ; women , 474 +/- 284 ) than in age- and sex-matched untreated patients ( men , 2634 +/- 418 ; women , 2011 +/- 1435 ) or in normal subjects ( men , 2870 +/- 1052 ; women , 1764 +/- 617 ) .
C0014556
temporal lobe epilepsy
C0031507
phenytoin