pre-s1 protein could be expressed in hepatocyte cytoplasm and on membrane in some cases with chronic viral hepatitis , cirrhosis and hepatocellular carcinoma ( hcc ) , and its expression was intimately associated with hbsag , hbcag in liver and hbv dna in serum , indicating that pre-s1 protein may represent the essential component of hepatitis b virus ( hbv ) and also serve as one of the markers of hbv infection .
C0023890
cirrhosis
C0023884
liver