since it was unknown whether the uncharged or the anionic form of hypoglycemic sulfonylureas and meglitinide is the effective modulator of atp-dependent k+ channels and insulin secretion , we studied the inhibitory effects of tolbutamide and meglitinide on the atp-dependent k+ current at different external ph .
C0038766
sulfonylureas
C0040374
tolbutamide