lovastatin ( mk-803 , mevinolin ) and simvastatin ( mk-733 , synvinolin ) , 2 highly potent 3-hydroxy-3-methylglutaryl coenzyme a ( hmg coa ) reductase inhibitors , have been heralded as breakthrough therapy for the treatment of atherosclerotic disease .
C0024027
mevinolin
C0074554
synvinolin