the fact that terminally differentiated cells such as pulmonary alveolar macrophages can activate benzo [ a ] pyrene and mediate an increase in frequencies of mutations and sister chromatid exchanges in cocultivated 'detector ' cell populations , i.e. , chinese hamster v79 cells , suggests that non-target cells of chemical carcinogens may play an important role in the activation of environmental carcinogens .
C0037211
sister chromatid exchanges
C0007634
cells