seven kinds of suppositories were constructed with oleaginous base materials ( witepsol h-15 ( h-15 ) and e-85 ( e-85 ] : a conventional type suppository containing valproic acid ( vpa ) mixed with e-85 ( i ) , a conventional type suppository containing sodium salt of vpa ( sodium valproate ) ( s-vpa ) mixed with h-15 ( ii ) , hollow type suppositories containing vpa in the forms of oily liquid ( free acid ) ( iii ) , macrogol 1000 or 6000 mixture ( iv or v ) , powder ( s-vpa ) ( vi ) and aqueous solution ( s-vpa was dissolved in 0.9 % nacl solution ) ( vii ) in each cavity .
C0037567
sodium salt
C0042291
vpa