administration of 5htp ( 50-200 mg/kg ) to naive guinea pigs , or of 5htp ( 20-80 mg/kg ) to carbidopa- ( 25 mg/kg 1 hr previously ) pretreated animals , markedly elevated brain 5-hydroxytryptamine ( 5ht ) concentrations but depressed whole brain tryptamine content .
C0006104
brain
C0086045
concentrations