these results indicate first , that all androgen-binding sites in prostatic nuclei can be released , either with nuclease/salt or trypsin digestion procedures to yield a 3 s androgen receptor with uniform binding characteristics , and second , that the androgen receptors are distributed between two intra-nuclear pools -- one containing about 10,000 molecules/nucleus sensitive to micrococcal nuclease digestion and salt and the other containing about 8,000 to 13,000 androgen receptors tightly bound to the nuclear matrix .
C0007610
nucleus
C0028581
nuclear matrix