by two-dimensional gel electrophoresis of proteins insoluble in detergents and high-salt buffer and immunofluorescence microscopy with a panel of polypeptide-specific antibodies to proteins of intermediate filaments ( if ) and desmosomes , we have characterized the cytoskeletons of normal human thyroid gland , several kinds of benign lesion ( goiter , hashimoto 's and graves ' diseases , adenomas ) , and the major thyroid carcinomas ( follicular , papillary , medullary , and anaplastic ) .
C0021769
proteins
C0010853
cytoskeletons