anticonvulsant properties of alpha-ethyl-alpha-methyl-gamma-thiobutyrolactone ( alpha-emtbl ) were compared with those of the antiepileptic drugs ethosuximide ( esm ) and valproate ( vpa ) by testing their ability to block seizures in mice caused by maximal electroshock ( mes ) , pentylenetetrazol ( ptz ) , picrotoxin ( picro ) , bicuculline ( bic ) , methyl-6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate ( dmcm ) , n-methyl-d , l-aspartate ( nmda ) , aminophylline ( amph ) , strychnine ( str ) , beta-ethyl-beta-methyl-gamma-thiobutyrolactone ( beta-emtbl ) , and t-butylbicyclophosphorothionate ( tbps ) .
C0036572
seizures
C0002575
aminophylline