patients were conditioned with 2 x 60 mg/kg of cyclophosphamide and 6 x 2 gy of total body irradiation and randomized to receive as graft-versus-host disease prophylaxis either the standard methotrexate regimen ( n = 61 ) or cyclosporine ( n = 51 ) , starting on day -1 as 12.5 mg/kg/d orally or as 3 mg/kg/d i.v . and later converting to p.o . when oral intake was tolerated .
C0018133
graft-versus-host disease
C0010592
cyclosporine