the characteristics of the reactions leading to the covalent binding of the n-methyl group of the azo derivative to microsomal protein and its metabolism to form the hydrocarbon , methane , possessed a number of similarities in the apparent kinetic parameters ( km and vmax ) , induction , and inhibition patterns indicating a common pathway of metabolism to form a reactive intermediate and the involvement of cytochrome p-450 .
C0025519
metabolism
C0010762
cytochrome p-450