during the time course of desensitization the beta ar kinase ( beta ark ) activity is translocated from a cytoplasmic to a plasma membrane location . beta ark translocation can also be effected by prostaglandin e1 ( pge1 ) suggesting that this beta ark may represent a more general enzyme capable of phosphorylating other adenylate cyclase-coupled receptors .
C0010834
cytoplasmic
C0007603
plasma membrane