subcutaneous transplantation of 1.0 x 10 ( 6 ) cells of a clonal tissue culture line of w/fu aml into 6- to 8-week-old rats produced local myeloblastomas in 8 -- 10 days which progressed to infiltration of regional nodes , replacement of greater than 90 % of the bone marrow , ascites , and fatal peripheral blood leukemia with concomitant hyperlysozymemia .
C0005953
bone
C0023418
concomitant