based on the enhanced incorporation of bromodeoxyuridine into origin-distal regions of dna during the in vitro runoff replication assay , we conclude that the active histone h5 gene in embryonic erythrocytes is preferentially replicated in the transcriptional direction from an origin in the 5'-flanking dna , whereas its inactive counterparts in msb-1 cells and chicken embryo fibroblasts are preferentially replicated in the opposite direction .
C0007634
cells
C0016030
fibroblasts