the enzymatic replication of plasmids containing the unique ( 245 base pair ) origin of the escherichia coli chromosome ( oric ) can be initiated with any of three enzyme priming systems : primase alone , rna polymerase alone , or both combined ( ogawa , t. , baker , t. a. , van der ende , a . & kornberg , a . ( 1985 ) proc . natl . acad . sci . usa 82 , 3562-3566 ) .
C0058594
primase
C0035681
rna polymerase