we report a case with multiple osseous manifestations affecting the entire skeleton , but mainly the skull ( osteolysis with absence of frontal bone ) , the vertebral column ( scoliosis with triple deviation ) , the upper right limb ( demineralisation and multiple pathological fractures ) and lower members ( fractures of the right and left femur ) with enlargement of the entire ventricular system and well marked scissures , signs of an cortico-subcortical atrophy shown by scanogram .
C0037303
skull
C0016732
frontal bone