studies in spontaneously hypertensive rats ( shr ) , which represent a model of genetically determined arterial hypertension , reveal that cardiac hypertrophy can be controlled by long-term blood pressure normalization with the use of various antihypertensive agents , such as arterial vasodilatators ( hydralazine ) , converting enzyme inhibitors ( captopril ) , beta-receptor blockers ( metoprolol ) , antiadrenergic substances ( alpha-methyldopa , guanethidine ) , and calcium antagonists ( nifedipine , felodipine ) .
C0020538
arterial hypertension
C0028066
nifedipine