previous in vivo studies in the rat detected only two hepatic mab-dna adducts , 3- ( deoxyguanosin-n2-yl ) -mab ( n2-dg ) and n- ( deoxyguanosin-8-yl ) -mab ( c8-dg ) , which respectively accounted for 25 % and 70 % of the total mab bound to dna at 8 h after a single dose of the carcinogen .
C0242958
dna adducts
C0012854
dna