the comparative efficacy of a 12-week acute treatment with 800 and 1600 mg cimetidine daily and the effectiveness of a 400-mg single-dose maintenance treatment versus placebo lasting 6 months were studied in a double-blind fashion in 30 and 24 patients , respectively , with gastroesophageal reflux ( ger ) disease .
C0008783
cimetidine
C0017168
gastroesophageal reflux