indirect immunofluorescent studies , in which monoclonal anti-alpha-tubulin antibodies were used , showed that these compounds ( 2-meoe2 greater than 2-ohe2 greater than e2 ) at high concentrations caused abnormal and fragmented polar formations as well as disorientated microtubule arrangement in the dividing mcf-7 and hela cells .
C0002318
alpha-tubulin
C0026046
microtubule