both the membrane potential change and the rapid sodium influx can be inhibited by a fast acting analog of amiloride , a sodium channel blocker , while valinomycin , a potassium ionophore , has no effect on the potential change nor on the sodium uptake , suggesting that the transmembrane potassium gradient is not important in the thrombin-induced depolarization .
C0002502
amiloride
C0032821
potassium