in this paper , we demonstrate that low concentrations ( 0.5-2.5 microm ) of 1,2-sn-dioctanoylglycerol ( dic8 ) , a potent diacylglycerol used in many previous studies to probe the role of protein kinase c ( pkc ) in cell activation , cause cytosolic alkalinization of human , mouse and pig t lymphocytes through pkc-mediated activation of the na+/h+ antiport .
C0007634
cell
C1383501
cytosolic