1 prostaglandin c ( 2 ) causes a prolonged fall in arterial blood pressure in the cat.2 at constant heart rate this fall in arterial pressure is accompanied by falls in stroke volume , left ventricular end diastolic pressure , and left ventricular dp/dt max.3 if mean aortic pressure and left ventricular end diastolic pressure are held constant as well as heart rate , prostaglandins c ( 2 ) and e ( 2 ) do not affect dp/dt max in the cat.4 in the dog , under similarly controlled conditions , prostaglandins c ( 2 ) and e ( 2 ) raise dp/dt max.5 we conclude that prostaglandins e ( 2 ) and c ( 2 ) have no direct inotropic action in the cat , but both have a direct positive inotropic action in the dog .
C0033554
prostaglandins
C0033559
prostaglandins e