the specific substitution , using highly selective techniques , of catalytic and/or noncatalytic zinc ions by cobaltous ions in horse liver alcohol dehydrogenase ( ec 1.1.1.1 ) has been studied with dissolved , crystalline and agarose-immobilised enzyme , in order to examine the effect of protein structure on the specificity of the metal exchange .
C0001942
alcohol
C0030016
ec 1