antibody-forming cells ( afc ) already existing in the bone marrow were not responsible for this activity since depletion of afc by passage through a sephadex g-10 column did not affect the numbers of anti-tnp afc and immunoglobulin-secreting cells ( igsc ) in the spleen of bmc-reconstituted mice when assayed 7 days after the transfer .
C0005953
bone marrow
C0005955
cells