the cytotoxic effects of three anticancer drugs , methotrexate ( mtx ) , 5-fluorouracil ( 5-fu ) and oridonin ( rub a ) , were investigated using a human gastric adenocarcinoma cell line ( mgc80-3 ) and a human esophageal cancer cell line ( caes-17 ) by means of colony-forming assay , dye exclusion test , measurement of incorporation of 3h-thymidine into dna and examination of mitotic index .
C0025677
methotrexate
C0014859
esophageal cancer