at peak effects , cardiac index increased from 2.53 to 3.07 l/min/m2 ( +20 % , p less than 0.01 ) , stroke volume index from 35 to 41 ml/beat/m2 ( +18 % , p less than 0.05 ) , stroke work index from 35 to 44 g x m/beat/m2 ( +26 % , p less than 0.05 ) , epinephrine from 0.05 to 0.15 ng/ml ( +200 % , p less than 0.05 ) , urine volume from 50 to 81 ml/h ( +61 % , p less than 0.05 ) , pulmonary capillary wedge pressure decreased from 23 to 18 mmhg ( -24 % , p less than 0.001 ) , mean pulmonary arterial pressure from 33 to 27 mmhg ( -19 % , p less than 0.001 ) , right atrial pressure from 10 to 7 mmhg ( -27 % , p less than 0.001 ) , systemic vascular resistance from 1735 to 1546 dyne x s x cm-5 ( -11 % , p less than 0.1 ) , pulmonary vascular resistance from 204 to 168 dyne x s x cm-5 ( -25 % , p less than 0.05 ) , arterio-venous oxygen difference from 6.09 to 5.36 ml/dl ( -12 % , p less than 0.05 ) , norepinephrine from 0.45 to 0.34 ng/ml ( -24 % , p less than 0.1 ) , renin activity 1.80 to 1.26 ng/ml/h ( -30 % , p less than 0.05 ) , respectively , whereas there were no significant changes in blood gases , heart rate , blood pressure , double product , aldosterone , urine na+ , k+ or lactate/pyruvate .
C0014563
epinephrine
C0028351
norepinephrine