the high hydrodynamic volume of the proteoglycans , the large polyanionic domain of their polysaccharide chains , the specific primary structure of their protein moiety and their localization both on the cell surface and in the extracellular matrix enable the proteinglycans to regulate cell growth and development , assembly of the extracellular matrix components and cell-matrix and cell-cell interactions .
C0033692
proteoglycans
C0015350
extracellular matrix