the four male patients with multiple hamartoma syndrome ( cowden 's disease ) in this report , have most of the previously reported findings associated with this syndrome and several important unreported findings that include multiple cutaneous trichilemmomas , cafe-au-lait spots , cutaneous squamous cell carcinoma , pathologic fracture , craniomegaly , probable malignant lung tumor , retinal glioma , drusens of the optic disk and retina , pseudotumor cerebri , mediastinal mass , and multiple small papillomatous lesions of the esophagus , stomach , and duodenum .
C0035335
retinal
C0035298
retina