compared to acv , 2'ndg was a more efficient substrate for hsv-1 thymidine kinase ( vmax/km for 2'ndg 30-fold higher than that of acv ) , whereas 2'ndg monophosphate is a more efficient substrate for gmp kinase ( vmax/km for 2'ndg monophosphate 492-fold higher than that for acv monophosphate ) .
C0001367
acv
C0017066
2'ndg