in incubations of cyclic imides ( ph 8 , 1 hr ) with a rat liver dihydropyrimidinase preparation from which omega-amidase had been removed , adipimide was classed as a good substrate and succinimide and glutarimide were classed as very poor but definite substrates . alpha-phenylsuccinimide , the n-demethylated metabolite of phensuximide , was a much better substrate than succinimide . alpha-phenylglutarimide was not a substrate .
C0020926
imides
C0038623
succinimide