at concentrations of 3.5 mm and above , alloxan caused an increase in lactate dehydrogenase ( ldh ) , glutamate-pyruvate transaminase ( gpt ) and intracellular potassium ( k+ ) leakage , all of which are indices of plasma membrane damage , and decreased the intracellular reduced glutathione content ( gsh ) of the cells .
C0007603
plasma membrane
C0007634
cells