intracerebroventricular administration of alpha-hanp increased significantly urine flow from 178 +/- 37 to 303 +/- 43 microliter/min ( mean +/- sem ) , sodium excretion from 27.3 +/- 8.9 to 54.4 +/- 10.5 , mumol/min , potassium excretion from 16.1 +/- 3.7 to 24.0 +/- 5.1 mumol/min , and osmolar and negative free water clearances , accompanied by a significant rise in renal blood flow from 77.0 +/- 14.6 to 94.9 +/- 16.9 ml/min .
C0086418
alpha-hanp
C1312248
27