these observations led to the following conclusions : 1 ) crf-li is an important hypothalamic regulator of adenohypophysial acth secretion , 2 ) crf-li in the hypophysial portal circulation is derived from crf-li-containing neurons within the paraventricular nuclei , and 3 ) glucocorticoid negative feedback effects can be exerted at the central level .
C0020663
hypothalamic
C0010132
crf-li