aminoglycoside-resistant variants of pseudomonas aeruginosa strain pao1 were readily selected by culturing the organism in medium containing increasing concentrations of gentamicin , tobramycin or amikacin until the strains were growing in a concentration of drug 128-fold greater than the minimal inhibitory concentration for the sensitive parent strain .
C0002556
aminoglycoside
C0002499
amikacin