addition of insulin in vitro to in vivo activated receptors increased the proportion of antiphosphotyrosine antibody-precipitable receptors in both tissues but increased the tyrosine kinase activity only in liver-derived receptors , indicating that most activatable insulin receptors reside on the plasmalemma in muscle whereas a significant proportion ( 35 % ) of liver receptors are not accessible to insulin in vivo .
C0034805
antibody
C0007603
plasmalemma