to compare the formation and persistence of alkylated dna bases in the g1- and s-phase compartments in liver in vivo , regenerating rat liver was exposed to [ 14c ] dimethylnitrosamine ( 0.57 mg/kg , ip injection ) or n- [ methyl14c ] -n-nitrosourea ( 3.3 mg/kg , intraportal injection ) during the g1 phase of the cell cycle ( 12 h after partial hepatectomy ) , or at 24 h after partial hepatectomy with 30 % hepatocytes in dna synthesis , or at 43 h after partial hepatectomy , 4 h after an hydroxyurea block from 14 to 39 h after operation with 80 % hepatocytes in dna synthesis .
C0023884
liver
C0193398
partial hepatectomy