to determine the influence of in vitro activity , pharmacokinetic properties , and therapeutic regimen on the antibacterial effect in vivo , we compared three cephalosporins , cefotiam , cefmenoxime , and ceftriaxone , in a rabbit model of experimental escherichia coli endocarditis after 4 days of treatment .
C0279516
antibacterial
C0007561
ceftriaxone