the mrna encoding heavy and light chains of a hybridoma-derived monoclonal igm , kappa anti-immunoglobulin ( rheumatoid factor ) and an igg3 , kappa anti-histone autoantibody from systemic lupus erythematosus and arthritis-prone mrl/mp-lpr/lpr mice have been molecularly cloned , and the nucleotide sequences corresponding to their variable regions have been determined .
C0035448
rheumatoid factor
C0004358
autoantibody