an investigation to rule out non-bronchial primary adenocarcinomas in randomized therapy studies should include : ( 1 ) a history of any previous operations on primary carcinomas , histologic comparisons , ( 2 ) a careful physical examination , ( 3 ) renal investigation , ( 4 ) colorectal investigation , ( 5 ) gynecologic investigation , and ( 6 ) a careful search for symptoms of primary tumors in other organs , especially the pancreas .
C0031809
physical examination
C0220825
investigation