feeding experiments with tryptophan samples labeled specifically with radioactive and stable isotopes have shown that pseudomonas aureofaciens converts this amino acid into pyrrolnitrin in such a way that the indole nitrogen gives rise to the nitro group , the amino group becomes the pyrrole nitrogen , c-3 of the precursor side chain becomes c-3 of the antibiotic , and h-2 of the indole ring and h-alpha of the side chain give rise to h-5 and h-2 of pyrrolnitrin , respectively .
C0034325
pyrrole
C0034336
pyrrolnitrin