the hypothesis that giant metamyelocytes eventually die within the marrow was supported by the observations that a significant proportion of these cells contain intracytoplasmic autophagic vacuoles , that some giant metamyelocytes suffer from a marked depression of rna and protein synthesis and that degenerating giant metamyelocytes can be recognized within the cytoplasm of some bone marrow macrophages .
C0007634
cells
C0010834
cytoplasm