an attempt was made in this study to determine the type of beta-adrenoceptor mediating this response.2 in anaesthetized , unilaterally nephrectomized cats , a comparison was made of the ability of two selective beta-adrenoceptor antagonists to block the tachycardia and hypotension caused by isoprenaline ( mediated respectively by beta ( 1 ) - and beta ( 2 ) -adrenoceptors ) and the release of renin caused by renal nerve stimulation.3 isoprenaline ( mean dose of 0.224 +/- 0.022 nmol/kg ) , increased heart rate by approximately 43 beats/min and decreased mean blood pressure by 47 mmhg .
C0022245
isoprenaline
C0039231
increased