to test the hypothesis that graves ' dermopathy is due to cross-reactivity of thyroid autoantibody ( ies ) with a cellular target in pretibial skin , we tested the serum and serum immunoglobulin fraction of 20 such patients for their effects on the metabolic activities of cultured thyrocytes ( rat frtl cells ) , human pretibial skin fibroblasts , and human fibroblasts of other origins .
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cells
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fibroblasts