it was found that ( i ) the majority of supercoiled sv40 dna molecules displayed a single binding site for the enzyme , ( ii ) the supercoiled structure of sv40 dna was frequently retained during transcription , and ( iii ) the majority of rna molecules synthesized from the supercoiled sv40 dna template showed no self-complementarity and sedimented relatively homogeneously in the 15s to 16s region of a sucrose gradient ( in contrast , the rna product synthesized from the nicked-circular sv40 dna template showed self-complementarity and sedimented heterogeneously ) .
C0040649
transcription
C0035668
rna