to determine the influence of inflammation and topical treatment with 5-aminosalicylic acid or prednisolone on arachidonic acid metabolism in vivo , we carried out a double-blind controlled study on the release of prostaglandin e2 and leukotriene b4 to the rectal lumen in 24 consecutive patients with proven distally located ulcerative colitis .
C0021368
inflammation
C0032950
arachidonic acid metabolism