hemoglobin solution , as a potential oxygen-carrying resuscitation fluid in blood volume replacement therapy , has two limitations : higher oxygen affinity ( p50 approximately 12-16 mm hg ) and shorter vascular retention time ( plasma half-disappearance time approximately 2-4 h ) of free hemoglobin as compared to hemoglobin in the red cells .
C0019046
hemoglobin
C0014792
red cells