gtp and its stable analogue , guanyl-5'-yl-imidodiphosphate ( gpp ( nh ) p ) , did not affect the affinity ( 100 pm ) or density ( 30 pmol/g wet wt ) of [ 3h ] spiperone binding sites , but did decrease the potency of a number of ergoline compounds including pergolide , lergotrile and ly-141865 , as well as dopamine agonists to displace [ 3h ] spiperone binding .
C0018353
gtp
C0018366
gpp ( nh ) p