based on current knowledge of in vitro drug activity , the clinical picture in such serious infections , and the experience with tmp-smz so far , it is predicted that tmp will be used either alone or in combination with other antibacterial agents ( such as the polymyxins , metronidazole , and various sulfonamides in different ratios ) for treatment of some of these infections .
C0041041
tmp
C0279516
antibacterial agents