in four in vivo tests in mice which measured humoral and cell-mediated immunity ( complement-dependent cellular cytotoxicity , complement-independent cellular cytotoxicity , delayed hypersensitivity and graft versus host reaction ) acyclovir showed no inhibitory effects at single doses up to 200 mg/kg given on day 2 after antigenic stimulation .
C0301896
cellular cytotoxicity
C0003320
antigenic