this study also suggests that surgical stress of sham operation may alter directly the na innervation of the spleen , possibly by inducing temporary retraction of na fibers of the parenchymal compartment , which is likely to reduce the availability of ne for interaction with cells of the immune system that possess adrenoceptors and are present adjacent to na varicosities in this region.4+ bilateral vagotomy ameliorated the effects of sham operation on na innervation ;
C0037993
spleen
C0020962
immune system