a total of 574 patients with cancer of the breast and no involvement of axillary lymph nodes were randomised , after simple mastectomy with axillary sampling , to receive either no adjuvant treatment or oral fluorouracil 500 mg , methotrexate 25 mg and chlorambucil 10 mg p.o . on day 1 and fluorouracil 500 mg and chlorambucil 10 mg p.o . on day 2 ( lmf ) every 21 days for eight cycles .
C0016360
fluorouracil
C0065134
lmf