desensitization of kitten atria with 30mum ( - ) isoprenaline resulted in a 6-fold and 15-fold increase in the ec50 's of ( - ) isoprenaline for its positive chronotropic effects ( sinus pacemakers ) and positive inotropic effects ( left atria ) , respectively , but only in a 2-fold increase of the ec50 of ( - ) isoprenaline for adenylyl cyclase stimulation in membrane particles from atria .
C1372804
positive
C0022245
isoprenaline