the data indicate that 1 ) the tmq analogs were antagonists of endoperoxide/thromboxane a2-mediated responses in rat aorta and human platelets involving a similar mechanism of action and 2 ) stereochemical requirements of these tmq analogs for activation of beta adrenoceptors and antagonism of endoperoxide/thromboxane a2-mediated responses are different .
C0086418
human
C0001643
beta adrenoceptors