in a mouse model using intraperitoneal inoculation of streptococcus pneumoniae type 3 , the 50 % effective dose , ed50 , after single doses one hour post-inoculation was considerably lower for ceftriaxone ( cro ) than for cefuroxime ( cxm ) and cefotaxime ( ctx ) , in spite of the same minimal inhibitory concentration , mic , of 0.02 mcg/ml against the pneumococcus for all 3 drugs .
C0007561
ceftriaxone
C0007554
cefotaxime