after acute beta-adrenergic blockade ( 5 mg atenolol intravenously ) in 11 patients with essential hypertension but no heart failure arterial blood pressure and inotropic state fell slightly ( -5.4 % and -7.5 % , respectively ) , but there was a definite decrease in heart rate ( -13.8 % ) , cardiac index ( -11.5 % ) and cardiac work ( -14.3 % ) .
C0018801
heart failure
C0018787
cardiac