with various cephalosporins as substrates marked discrepancies in the mode of inhibition were observed : cefacedone revealed merely noncompetitive inhibition , cefazolin and cefoperazone demonstrated mixed-inhibition kinetics , and with cephalothin as the substrate enzyme kinetics strongly suggested binding of a second azthreonam molecule .
C3536856
cephalosporins
C0007552
cefoperazone