trazodone ( 1 mg iv or 0.25 mg ivt ) produced hypotension and bradycardia that is consistent with the activation of noradrenergic neurons in the anterior hypothalamus perhaps as a result of trazodone acting on presynaptic alpha 2 receptors or on presynaptic serotonin receptors to increase the release of norepinephrine .
C0020649
hypotension
C0028351
norepinephrine