with a median follow-up of 4 years , antithymocyte globulin plus steroids in combination with methotrexate as graft vs. host prophylaxis was associated with less severe growth suppression than methotrexate alone , while there were no significant associations between growth during the first 2 years following transplant and prepubertal status at transplant ( as defined by age ) , graft vs. host disease , thyroid or gonadal function , or previous therapies received by the leukemia patients .
C0025677
methotrexate
C0023418
patients