the theory suggests that final effects on alpha-1 mediated neurotransmission may be produced not only by drugs which have direct effects on the alpha-1 receptor or its second messenger , but also by drugs having effects on neurotransmitter systems such as acetylcholine , gaba , and serotonin , among others , which modulate the activity of central norepinephrine neurons or , via feedback mechanisms , by drugs having effects on adrenergic receptors other than the alpha-1 receptor itself .
C0027793
neurotransmission
C0027908
neurotransmitter