the ability of cytoplasmic extracts from t cells undergoing antigen-specific , il-2-dependent proliferation to induce dna synthesis in isolated , quiescent nuclei was markedly inhibited in the presence of aprotinin , providing strong evidence that a cytoplasmic activator of dna replication , adr , is involved in the signal transduction process for antigen-specific , il-2-dependent t cell proliferation .
C0039194
t cells
C1155046
t cell proliferation