it is indicated ( a ) that the sites of the synthesis for the melanosomal protein and tyrosinase are different , ( b ) that the melanosomal structural protein is accumulated in the dilated vacuole of smooth er from which the stage i melanosome is synthesized , ( c ) that the synthesis of melanosomal protein becomes markedly aberrant and directly reflects the abnormal fine structure of the melanosome and ( d ) the heterogeneity in synthesis of melanosomal protein as expressed by moab hmsa-1 and hmsa-2 is a useful adjunct for immunohistopathological differentiation of malignant melanoma cells from benign nevoid cells and normal melanocytes .
C0230789
smooth er
C0007634
cells