the role of ornithine decarboxylase ( orndcase , ec 4.1.1.17 ) and of the polyamines [ putrescine ( put ) , spermidine ( spd ) , and spermine ( spm ) ] in mouse skin tumor promotion was investigated by the use of alpha-difluoromethylornithine ( chf2-orn ) , an enzyme-activated irreversible inhibitor of orndcase .
C0029282
ornithine decarboxylase
C0002260
alpha-difluoromethylornithine