the modification of the alpha-amino group on val-1 ( beta ) of hemoglobin a as a ketoamine ( 2-oxo-3-hydroxypropyl group ) apparently lowers the pka of the alpha-amino group of the protein , since this derivative of hemoglobin elutes earlier on carboxymethylcellulose columns than the derivatives containing 2-oxo-3-hydroxypropyl groups on the epsilon-amino groups , and unmodified hemoglobin a .
C0019046
hemoglobin
C0019016
hemoglobin a