we report here that ( 1 ) ph1 in human fibroblasts is controlled by a membrane-bound na+/h+ exchanger , which rapidly restores ph1 after an acute cytoplasmic acidification , and ( 2 ) epidermal growth factor ( egf ) and serum factors induce a rapid and persistent elevation of ph1 by modifying the ph1 sensitivity of the na+h+ exchanger .
C0086418
human
C0242275
epidermal growth factor