in 101 breast cancer patients , measurement of oestrogen receptor status in multiple biopsies across a tumour reveals a highly significant difference in the proportion of patients remaining either disease-free ( p less than 0.04 ) or alive ( p less than 0.005 ) , when those with uniformly receptor positive ( ++ ) primary tumours are matched with clinically comparable patients whose tumours were homogeneously receptor negative ( -- ) .
C0027651
tumour
C0012634
disease