the effects of ligand binding on the accessibility of both tyrosine and tryptophan residues to the quencher are modest in all cases , though the changes are in the same direction as seen using other physicochemical techniques such as hydrogen exchange ( m. lennick and n.m. allewell , proc . natl . acad . sci . u.s.a. 78 ( 1981 ) 6759 ) .
C1517880
ligand binding
C1418943
proc