relative to sham operated rats , endocrine effects of the ovarian grafts were as follows : 1 ) animals with ovarian grafts showed an advancement of puberty , 2 ) rats with bilateral grafts showed more 5 day estrous cycles and higher fsh levels , 3 ) hemi-ovariectomy of animals with bilateral grafts produced a greater increase in both lh and fsh 6-8 hr post-surgery in contrast to controls which only showed an increase in serum fsh levels , 4 ) weights of the bilateral grafts were comparable to intact ovaries , but the unilateral grafts were small and comparable to their original size at the time of transplantation ( the intact ovary showing compensatory hypertrophy ) , 5 ) both control and bilateral ovarian graft groups showed ovarian compensatory hypertrophy , 6 ) removal of the small unilateral ovarian graft had no detectable endocrine effect on the remaining intact ovary which had already undergone compensatory hypertrophy , 7 ) removal of the intact ovary of rats with a unilateral graft produced a remarkable increase in the weight of the remaining small autograft such that these animals had the largest remaining gonad as well as higher uterine weights than controls .
C0029939
ovary
C0029936
removal