in order to estimate the relative magnitude of the two alternative pathways of monodeiodination of thyroxine ( t4 ) in adult humans , the metabolic clearance rates ( mcr ) and production rates ( pr ) of 3,3',5'-triiodothyronine ( reverse-t3 , rt3 ) and of 3,5,3'-triiodothyronine ( t3 ) were determined in six euthyroid control subjects ( c ) and in five hypothyroid patients ( h ) receiving l-t4 as replacement therapy ( 0.15-0.3 mg/day ) .
C0041014
triiodothyronine
C0020676
hypothyroid