1 the effects of substance p ( sp ) on the membrane and contractile properties of the smooth muscle cell , or on neuro-effector transmission in the guinea-pig ileum were observed by means of microelectrodes , double sucrose gap and tension recording.2 sp ( 10 ( -13 ) -10 ( -10 ) m ) induced a phasic contraction of longitudinal muscle strips , but did not change the muscle tone of circular muscle strips , in concentrations up to 10 ( -8 ) m.3 sp ( 10 ( -10 ) -10 ( -8 ) m ) evoked three different membrane responses in longitudinal muscle cells : ( i ) bursts of spike discharges with no significant change in the membrane potential and input membrane resistance ;
C1135918
smooth muscle cell
C0026845
muscle