type ii tyrosinemia ( richner-hanhart syndrome ) is a familial aminoacid disorder , clinically characterized by ocular changes ( keratitis ) , palmo-plantar hyperkeratosis , no constant mental changes with mental deterioration , abnormal urinary excretion and high serum tyrosine level in consequence of the absence of tyrosine-aminotransferase .
C0015392
ocular
C0022568
keratitis