these data , correlating changes in the environment of the noncatalytic or regulatory nucleotide binding site on the ca2+-atpase with coupling activity , indicate that uncoupling is an intramolecular process , involving a ligand binding site on the atpase , and that exclusion of h2o from the site occupied by noncatalytic nucleotides , during at least part of the catalytic cycle , is an event associated with energy transduction .
C0001476
ca2
C0001473
atpase