a detailed morphologic and serologic analysis of this disease revealed the following : ( a ) a 75 % incidence of synovial and periarticular inflammation , very similar to human rheumatoid arthritis , in 5-6 mo-old females , ( b ) close associations between presence of joint inflammation and subsynovial and/or periarticular vasculitis , and ( c ) a close correlation between presence of circulating igm rheumatoid factor ( rf ) and demonstrable synovial and/or joint pathology , i.e. , 95 % of mice with significant levels of igmrf had synovitis and/or arthritis .
C0003873
rheumatoid arthritis
C0022417
joint