this assay enabled us to isolate two hybridomas secreting antibodies ( designated 2f4 and 4g12 ) that recognized il-1 alpha and not interleukin-1 beta as judged by the ability of the antibodies to : ( a ) precipitate il-1 alpha , ( b ) inhibit the binding of 125i-il-1 alpha to the il-1 receptor on el4 cells , ( c ) inhibit the biological activity of il-1 alpha as measured in a lectin-induced , il-1-dependent thymocyte proliferation assay .
C0021753
interleukin-1 beta
C0021755
il-1