comparison of the extent of methylation in mouse dna fragments rendered mgcl2 soluble after mild dnase ii digestion of nuclei , with different reassociation rate and nucleoli-bound , revealed the existence of 3 regions of the genome particularly 5-methylcytosine-rich : the sequences considered to be related to the transcriptionally active chromatin with the highest content of this base and fast reassociating , as well as nucleolar dna with somewhat lower proportion of the methylated cytosines .
C0007610
nuclei
C0007609
nucleoli