lysosomal enzymes are released in the absence of phagocytosis when cytochalasin b ( 5 mug/ml ) converts polymorphonuclear leukocytes ( pmn ) to secretory cells : lysosomes merge directly with the plasma membrane upon encounter of pmn with zymosan , and cells selectively extrude substantial proportions of lysosomal , but not cytoplasmic enzymes . beta-adrenergic stimulation of human leukocytes produced a dose-related reduction in beta-glucuronidase release ( blocked by 10 ( -6 ) m propranolol ) whereas alpha-adrenergic stimulation ( phenylephrine plus propranolol ) was ineffective .
C0024369
lysosomes
C0010834
cytoplasmic