in a prospective , randomized , double-masked study , 2 % epinephrine applied topically twice each day for two weeks to the eyes of patients with glaucoma or ocular hypertension caused an 8.1 +/- 1.4-mm hg ( mean +/- s.e.m . ) reduction of intraocular pressure in placebo-treated patients , but only a 1.9 +/- 0.6-mm hg decrease in patients treated with 25 mg of orally administered indomethacin four times each day ( p less than .0005 ) .
C0017601
glaucoma
C0028840
ocular hypertension