in separate studies , when the plasma glucose level was clamped at baseline values by a variable rate of glucose infusion , the agr was suppressed during the tolbutamide infusion in all 7 normal [ change in agr ( delta agr ) = -35 +/- 12 pg/ml ; p less than 0.05 ] and all 6 noninsulin-dependent diabetic subjects ( delta agr = -14 +/- 5 pg/ml , p less than .05 ) .
C0040374
tolbutamide
C0011860
noninsulin-dependent diabetic