a novel approach was adopted in which these responses were assessed following reduction of muscarinic receptor concentration ( machr ) in the brain ( assessed from [ 3h ] qnb binding ) by the alkylating derivative of oxotremorine , n- [ 4- ( 2-chloroethylmethylamino ) ] -2-pyrrolidone ( bm 123 ) .
C0086045
concentration
C0006104
brain