activities of several steroid metabolizing enzymes ( steroid sulfate-sulfatase , 17 beta-hydroxysteroid dehydrogenase , 5 alpha-reductase , and 3 alpha beta-hydroxysteroid dehydrogenase ) as well as total tissue content and subcellular distribution ( nuclear-extranuclear ) of several androgen precursors , active androgens , and androgen deactivation products ( dhea sulfate , dhea , 5-androstenediol , 4-androstenedione , testosterone , dht , and 3 alpha-androstanediol ) were quantified in primary tumors and lymph node metastases of human prostatic cancer obtained from patients without previous endocrine manipulation .
C0039602
5 alpha-reductase
C0033572
prostatic