in contrast , a progressive increase in igg1 anti-tg affinity was seen in clinically euthyroid individuals compared with their relatives with thyroid disease and high titred hashimoto 's disease patients , suggesting that either rising titres of high affinity igg1 anti-tg or affinity maturation of igg1 anti-tg may be indicative of impending hypothyroidism .
C0040123
tg
C0020676
hypothyroidism