at 63 days , prior to clinical evidence of leukemia , glucose-metabolizing enzymes from spleen mnc changed , and there were decreases in ache from both blood and spleen mnc that progressively decreased at 83 days , when there was depressed body weight , splenomegaly , elevated wbc , depressed rbc , hypoglycemia , hyperbilirubinemia , and elevated serum enzyme levels .
C0017725
glucose
C0020615
hypoglycemia