to determine whether hyperglycaemia alters the accuracy with which [ 2 ( 3 ) h ] and [ 3 ( 3 ) h ] glucose reflect glucose turnover measured with [ 6 ( 14 ) c ] glucose in patients with type 1 ( insulin-dependent ) diabetes mellitus , glucose utilisation rates were measured during a simultaneous infusion of [ 2 ( 3 ) h ] , [ 3 ( 3 ) h ] and [ 6 ( 14 ) c ] glucose after maintenance of normoglycaemia overnight and when glucose concentrations were clamped at 5.3 , 7.5 and 9.7 mmol/l while insulin and glucagon concentrations were held constant .
C0020456
hyperglycaemia
C0021641
insulin