to test whether metformin treatment might improve peripheral insulin sensitivity in non insulin dependent diabetes , we measured peripheral glucose uptake in 12 non insulin dependent diabetics before ( a ) and after 4 weeks ( b ) of metformin therapy ( 2 x 850 mg/day ) by the hyperinsulinemic clamp technique ( 80 mu/m2/min ) .
C0011860
non insulin dependent diabetics
C0025598
metformin