in an infectious poliovirus cdna construct , the determinant encoding antigenic epitope n-ag1 ( in a loop located between two beta-strands in poly-peptide vp1 ) was altered by site-directed mutagenesis , to be partially similar with the determinants for presumptive epitopes in polypeptides vp1 or vp3 of hepatitis a virus ( hav ) .
C0003320
antigenic
C0003316
epitopes