a role of glu-468 in the mechanism of channel formation or function was implied by the changes determined in vitro of channel parameters relative to the wild type : ( i ) the relatively small rates of current increase measured for colicin cooh-terminal peptide derived from the mutants , ( ii ) the small values of steady-state conductance of mutant peptide at ph 3.5 , and ( iii ) the reduced anion selectivity of peptide from the serine mutant .
C0021966
i
C0003075
anion