the bone marrow at 4 and 12 hours exhibits an increase in number , mitoses , size , and cytoplasmic granulation of myeloblasts and promyelocytes but a decrease in mature neutrophils , demonstrating that g-csf acts not only as a mitogen and growth factor for early cells in the myeloid series but also as a releasing factor for mature marrow neutrophils .
C0005953
bone marrow
C0079459
g-csf