a greater than 40-fold difference in rates of chlorpyrifosoxon hydrolysis observed between rat ( low activity ) and rabbit sera ( high activity ) correlated well with the reported large differences in ld50 values for chlorpyrifos in these two animals , consistent with an important role of serum paraoxonase in detoxification of organophosphorus pesticides in vivo .
C0020291
hydrolysis
C0052451
paraoxonase