colchicine produced notable changes in the tissue of both species : 1 ) the secretion of lipid droplets and golgi vesicle contents ( exocytosis ) was inhibited and the droplets and vesicles became randomly distributed throughout the cell , 2 ) the golgi apparatus was significantly reduced in size , 3 ) casein and lipid continued to be synthesized as evidenced by greater numbers of secretory vesicles and increased sizes of casein micelles and lipid droplets , 4 ) secretory vesicles showed a propensity to cluster around lipid droplets , 5 ) isolated microtubules were found occasionally in the control tissue , ordinarily in the vicinity of the golgi apparatus , but rarely in the colchicine-treated tissue .
C0007634
cell
C0230704
lipid droplets