hybrids formed by fusion of either human acute lymphoblastic or chronic lymphocytic leukemia cells and the mouse myeloma p3.x63.ag8/653 have been used to show that the expression of two cell surface antigens , bp37 and p76 , associated with b cell activation and detected by the monoclonal antibodies bb1 and bb2 , respectively , segregate with human chromosomes 12 and 19 , respectively .
C0003320
antigens
C1155003
b cell activation