twelve analogs of the antifolates aminopterin ( amt ) and methotrexate ( mtx ) having the - ( ch2 ) 2cooh moiety replaced by - ( ch2 ) nx , where x = so3h , po3h2 or nh2 , were evaluated as inhibitors of fpgs isolated from human liver .
C0002583
aminopterin
C0025677
methotrexate