following treatment with nocturnal , pulsatile , s.c. infusions of lh-rh ( 50 micrograms/night ) for nine nights a twenty-year-old patient with hypogonadotropic hypogonadism presented a markedly enhanced , biphasic secretion of lh during an lh-rh infusion test ( 200 micrograms lh-rh i.v. , t = 4 hours ) indicating a hypothalamic defect and a deficiency in endogenous lh-rh production .
C0020663
hypothalamic
C0023610
lh-rh