the structure of the adduct supports a pathway involving enzyme-catalyzed conjugation of 1,2-dibromoethane with glutathione , non-enzymatic dehydrohalogenation of the resulting half-mustard to form a cyclic episulfonium ion , and attack of the n7 nitrogen of dna guanine on the episulfonium ion to generate this major dna adduct , which may be related to the carcinogenicity of this chemical .
C0012854
dna
C0242958
dna adduct