thus , we conclude ( 1 ) that igf-i stimulates both cell replication and differentiated functions in cultured murine osteoblasts and ( 2 ) that igf-i and 1,25 ( oh ) 2d3 have the synergistic effect on alp activity and the additive effect on collagen synthesis in mc3t3-e1 cells .
C0007590
cell replication
C0007634
cells