the synthesis of cat is constitutive in e. coli and other gram-negative bacteria which harbor plasmids bearing the structural gene for the enzyme , whereas gram-positive bacteria such as staphylococci and streptococci synthesize cat only in the presence of chloramphenicol and related compounds , especially those with the same stereochemistry of the parent compound and which lack antibiotic activity and a site of acetylation ( 3-deoxychloramphenicol ) .
C0008169
cat
C0001038
acetylation