this suggests at least two possibilities : ( a ) that loss of controlled nuclear division in bhk cells is closely associated with or required for tumorigenicity , with in vivo passage selecting for a rare tumorigenic variant or ( b ) that loss of controlled nuclear division is secondary to tumorigenicity and results when cells are passed in vivo , i.e. , in vivo passage has the direct effect of causing cells to lose controlled nuclear division .
C0007634
the
C1155789
nuclear division