we have studied the effect of organic co-solvents ( monohydric alcohols and formamide ) on the dimer-tetramer equilibrium of human haemoglobin by measuring the dependence of oxygen affinity upon haemoglobin concentration over a 100-fold concentration range and analysing the data with a modified monod-wyman-changeux model in which the equilibrium ( tetramer ) in equilibrium with ( dimer ) + ( dimer ) was taken into account .
C0019046
haemoglobin
C0019016
haemoglobin