these differences in enzyme localization imply that acetoacetate is converted into acetoacetyl-coa only by 3-oxo acid-coa transferase in the mitochondria and cytoplasm of the chick brain , whereas , in the rat brain , this reaction is performed by 3-oxo acid-coa transferase in mitochondria and by acetoacetyl-coa synthetase in the cytosol .
C0010834
cytoplasm
C0026237
mitochondria