at least two modes of binding are identified by a new two-stage elution procedure that discriminates between nucleosomes which are retained by the hg-column because of their salt-labile associations with sh-reactive non-histone proteins , and nucleosomes in which a conformational change has made the thiol groups of histone h3 accessible to sh-reagents .
C0028623
nucleosomes
C0019647
histone h3