according to the most widely accepted pathogenetic theory , this phenomenon represents , together with vertebral collapse and increased bone density , a pathognomonic sign of ischemic osteonecrosis of the vertebrae , similar to osteonecrosis of the head of the thigh bone and , like this , favored by many different factors , such as old age , repeated traumas , alcoholism , rheumatoid arthritis , arteriosclerosis and corticosteroid therapy .
C0029445
osteonecrosis
C0262950
bone