this soluble immune suppressor supernate of immunoglobulin production ( ctc-siss-b ) shares a number of features with the previously described suppressive mediator elaborated by concanavalin a-activated human peripheral t cells ( siss-b ) including : ( a ) the inhibition by a noncytotoxic mechanism , ( b ) the suppression of immunoglobulin biosynthesis either through direct action on the b cell or indirect action via the monocyte , ( c ) the loss of inhibition in the presence of the monosaccharide l-rhamnose , ( d ) the elaboration by cells irradiated with 500 ro 2,000 rad , and ( e ) molecular weights of 60,000 -- 90,000 .
C1516008
suppression
C0007634
the