morphine and levorphanol , added in vitro , inhibited the stimulation-induced overflow of tritium at similar concentrations and to a similar degree in slices from morphineand placebo-pretreated animals. -- it is concluded that , during chronic treatment with morphine , an adaptation takes place in the brain to compensate for the acute effect of narcotic analgesics , i.e . inhibition of the release of noradrenaline by nerve impulses .
C0086045
concentrations
C0006104
brain