using recently established human colon carcinoma and renal cell carcinoma under defined in vitro conditions , we observed intertumoral and intratumoral heterogeneity and polarity of responses to tgf-beta ( growth inhibition or stimulation ) that did not correlate with the metastatic phenotype of the cancer cells as assessed in athymic nude mice .
C0086418
human
C1366557
tgf-beta