these studies were initiated to determine ( 1 ) if cisplatin ( cis-ddp ) -induced hyperglucagonemia is related to decreased hormone degradation , ( 2 ) the relationship between impaired kidney function associated with cis-ddp nephrotoxicity and hyperglucagonemia , and ( 3 ) the contribution of cis-ddp-induced hyperglucagonemia to disturbances in glucose metabolism in male f-344 rats .
C0035078
impaired kidney function
C0008838
cis-ddp