in conclusion , ( a ) physiological increments in the plasma glucose concentration , independent of their effects on insulin and glucagon secretion , can significantly reduce net hepatic glucose production in vivo but at levels as high as 230 mg/dl can not induce net hepatic glucose storage and ( b ) in the presence of basal insulin the ability of hyperglycemia to stimulate net hepatic glucose storage is influenced by the plasma glucagon concentration .
C0021641
insulin
C0020456
hyperglycemia