to investigate the mechanism by which alpha-adrenoceptor blocking drugs prevent ventricular arrhythmias associated with myocardial ischaemia and reperfusion , we studied the effects of alpha blockade , alpha-adrenoceptor agonists , and myocardial catecholamine depletion on arrhythmias and cellular electrophysiology during ischaemia and reperfusion in isolated perfused guinea pig hearts .
C0085612
ventricular arrhythmias
C0003811
arrhythmias