ro 23-9424 demonstrated significant activity against all strains tested in systemic infections , including those strains resistant in vivo to cefotaxime ( staphylococcus aureus 753 , serratia marcescens sm and pseudomonas aeruginosa 8780 ) and fleroxacin ( streptococcus pneumoniae 6301 and streptococcus pyogenes .
C0243026
systemic
C0007554
cefotaxime