thus , the known difference in 2 , 3-dpg binding to fetal or adult deoxyhemoglobin does not measurably influence the erythrocyte 2 , 3-dpg concentration , indicating that in vivo the 2 , 3-dpg synthesis in hypoxia is virtually regulated by the erythrocyte ph , which in turn is determined by plasma ph and the oxygenation state of hemoglobin .
C0014792
erythrocyte
C0019046
hemoglobin