data derived from previously published studies that utilized single-pass perfusions of mouse livers in situ with parathion or methyl parathion were analyzed to determine liver/perfusate kp values from the equation kp = ( t 1/2ss ) ( q ) / ( 0.693 ) ( vh ) , where kp is the liver/perfusate distribution ratio , t 1/2ss is the half-life for approach to steady state of the chemical , vh is the liver volume , and q is the perfusate flow rate .
C0030514
parathion
C0025709
methyl