monolayer cultures of a rat hepatocyte cell line shown previously to accumulate a nuclear pool of free heparan sulfate chains that are enriched in sulfated glucuronic acid ( glca ) residues ( fedarko , n.s. , and conrad , h.e. , ( 1986 ) j. cell biol . 587-599 ) were incubated with 35so4 ( 2- ) , and the rate of appearance of heparan [ 35s ] sulfate in the nuclei was measured .
C0007634
cell
C0007610
nuclei