we propose that nucleotide selection during ongoing dna synthesis results largely from the different relative rates of forward ( beta ) and backward ( -alpha ) reactions involving the [ dnan x dnmp x ppi ] intermediate : the forward ( incorporation ) reaction is expected to predominate for the correct nucleotide , whereas the backward ( abortive ) reaction is expected to predominate for incorrect nucleotides .
C0011529
dnmp
C0028630
nucleotides