this transcriptional activation of the malic enzyme gene is dose dependent , i.e . the treatment of euthyroid male rats with daily doses of 17.5 and 35 mg of dhea/100 g of body weight for 7 days elevated the rate of malic enzyme gene transcription in liver above the basal levels 4-5- and 8-9-fold , respectively .
C0162493
transcriptional activation
C0040649
gene transcription