when a small dose of lipopolysaccharide was injected into mice previously injected with heat-killed propionibacterium acnes , most of the animals died with acute hepatic failure which was produced by cytotoxic factors from activated adherent cells , and liver cells were injured by antibody-dependent cell-mediated cytotoxic ( adcc ) reaction or activated macrophages in vitro .
C0162557
acute hepatic failure
C0227525
liver cells