structural analyses of a hereditary abnormal antithrombin iii , antithrombin iii toyama , which has normal progressive antithrombin activity but no heparin cofactor activity , have been carried out to elucidate the molecular abnormality causing recurrent thrombophlebitis of a patient and to identify an amino acid residue essential for the binding with heparin .
C0040046
thrombophlebitis
C0019134
heparin