these data indicate that the cytosolic glutathione s-transferases interact with an oxidative microsomal metabolite of iproniazid to enzymatically produce an s- ( 2-propyl ) glutathione conjugate and thus prevent formation of a reactive species which would otherwise chemically decompose to yield hydrocarbons or to covalently bind to cellular macromolecules .
C1383501
cytosolic
C0007634
cellular