these data indicate that different central mechanisms are involved in mediating the hypotension and bradycardia induced by centrally administered clonidine and adrenaline and do not , therefore , support the hypothesis that the hypotensive effects of clonidine ( i.c.v . ) are mediated by central adrenaline receptor activation in urethane-anaesthetized spontaneous hypertensive rats .
C0428977
bradycardia
C0014563
adrenaline