however , cardiac beta 1- and beta 2-adrenoceptors seem to be differentially affected in different kinds of heart failure : while in end-stage idiopathic dilated cardiomyopathy the diminished cardiac beta-adrenoceptor function is due to a selective loss in beta 1-adrenoceptors , in mitral valve disease , tetralogy of fallot and end-stage ischaemic cardiomyopathy it is characterized by a concomitant reduction in beta 1- and beta 2-adrenoceptors .
C0018787
cardiac
C0018801
heart failure