these results suggest that lithium and disulfiram exert their synergistic effect on hx hypnosis by acting on the 5-ht system and that an accumulation of 5-hydroxyindoleacetaldehyde , an active metabolite of 5-ht , may be responsible for the increase in the brain sensitivity to barbiturates caused by these drugs .
C0019469
hx
C0004745
barbiturates