in the prepubertal mice , severe testicular damage such as vacuolation and swelling of the round spermatids , necrosis of the late elongated spermatids in stages i to viii , abnormal meiosis in stage xix , and a marked cellular exfoliation into the lumen were detected 1 day after administration of the 150 mg/kg dose .
C0025186
meiosis
C0007634
cellular