in the search for compounds active against human immunodeficiency virus ( hiv ) , we have found that members of a novel series of tetrahydro-imidazo [ 4,5,1-jk ] [ 1,4 ] -benzodiazepine-2 ( 1h ) -one and -thione ( tibo ) derivatives inhibit the replication of hiv-1 , the main aetiological agent of aids , but not of hiv-2 , or of any other dna or rna viruses .
C0598312
replication
C0012854
dna