administration of cyproheptadine for four months to a patient with nelson 's syndrome was associated with evidence of skin lightening , decreased plasma acth concentrations , return of a normal circadian periodicity of plasma acth concentrations , and lack of responsiveness of plasma acth concentrations to trf administration , in contrast to the response seen in the untreated state .
C0010620
cyproheptadine
C0027577
nelson 's