the transformant 11564 which was studied in detail , has the same characteristics as the original mutant 10248 including continued growth in medium containing 8-br-camp , an increase in the ka for camp activation of the kinase , a greatly reduced amount of type ii protein kinase activity , an altered incorporation of the photoaffinity label 8-n3 [ 32p ] camp into the ri* subunit of pki , and an absence of camp-dependent phosphorylation of a mr = 52,000 protein in intact cells .
C0031727
kinase
C0031715
phosphorylation