the relaxant effect of gaba and ( - ) -baclofen persisted in guinea-pigs pretreated ( 1-2 min ) with picrotoxin ( 1.6 mumol kg-1 ) , whereas it was significantly reduced in animals injected 1 min beforehand with 5-aminovaleric acid ( 0.2 mmol ) .
C0016904
gaba
C0004609
baclofen