the increase was attributed to the increased cytosolic ca2+ in mg2+-deficiency which can cause : 1 ) increase of hydro and endoperoxide levels as a consequence of the increase of arachidonic acid release and eicosanoid synthesis in mg2+-deficiency , and 2 ) inhibition of the mitochondrial respiratory activity and activation of ca2+-dependent proteases which may activate the conversion of xanthine dehydrogenase to xanthine oxidase which generates active o2 species .
C1383501
cytosolic
C0043316
xanthine dehydrogenase