the results showed that prazosin proved adequate as sole medication in 6 patients during the entire observation period and satisfactory reduction of blood pressure ( less than 90 mmhg diastolic ) could be achieved and maintained in over 80 % of patients with a combination of prazosin and beta-blockers , with supplementary treatment with diuretics in some cases as and when necessary because of fluid retention and consequent loss of efficacy .
C0020649
reduction
C0032912
prazosin