in the isolated blood-perfused canine ventricular tissue , antiarrhythmic agents could be classified as having : 1 ) positive chronotropic and inotropic effects ( procainamide ) , 2 ) negative chronotropic but positive inotropic effects ( quinidine ) , and 3 ) negative chronotropic and inotropic effects ( lidocaine , ajmaline , diphenylhydantoin , and propranolol ) .
C0003195
antiarrhythmic agents
C0033216
procainamide