a very high degree of specific dexamethasone binding to chromatin and a marked in vitro inhibition of rna-synthesizing capacity of purified lymphoma cell nuclei was found to correlate closely with the very strong cytolethal effect of glucocorticoids on lymphoma cells ( in this case neither b- nor t-cells ) of a young patient , whose condition rapidly and unexpectedly deteriorated after a total dose fo 90 mg of prednisone given during a two day period ;
C0008546
chromatin
C0007610
of