increase of serum ige with frequent localization of ige in the germinal centres , mast cell hyperplasia in lymph nodes and changes of specific granules in the infiltrated eosinophils , such as roughness of the matrix and appearance of tubular structures together with fusing and disappearance of the core , were demonstrated in eosinophilic granuloma of the soft tissue , so-called kimura 's disease , in association with increase of anti-candida ige antibody .
C0282491
germinal centres
C0024204
lymph nodes