although alpha-p18 caused little increase in the cytolysis of platelets treated with c5b-9 ( total release of lactate dehydrogenase less than 5 % ) , it markedly increased the cell stimulatory responses induced by these complement proteins , including , secretion from platelet alpha- and dense granules , conformational activation of cell surface gp iib-iiia , release of membrane microparticles from the platelet surface , and exposure of new membrane binding sites for components of the prothrombinase enzyme complex .
C1536403
cytolysis
C0007634
cell