the dependence of the apparent association constant for microtubule formation on ligand concentration was analyzed by the linked function theory of wyman ( wyman , j . ( 1964 ) , adv . protein chem . 19 , 224-286 ) , leading to the conclusion that the formation of a tubulin-tubulin contact involves the binding of one additional magnesium ion per tubulin dimer .
C0026046
microtubule
C0041348
tubulin