maximum development of the binding spectrum in hepatocytes was always within one second of the addition of each carbamate , indicating that for these carbamates membrane permeability was not rate limiting for access to , and metabolism by , cytochrome p-450 and that much of the cells ' cytochrome p-450 was unoccupied by endogenous substrates .
C0025519
metabolism
C0010762
cytochrome p-450