the newly introduced alpha 2-adrenoceptor antagonist bdf 8933 , which is an imidazoline derivative , stimulates insulin release as well , while the irreversible alpha-adrenoceptor blocking agent benextramine of different structure failed to do so , even when being present in concentrations blocking the alpha 2-adrenoceptor-mediated effects of clonidine .
C1449836
imidazoline
C0009014
clonidine