however , upon investigation of these genetic deficiencies in guinea pigs for signs of dysregulation in the humoral immune system and especially autoantibodies , many complement-deficient guinea pigs ( greater than 50 % ) had elevated levels of serum igm and higher concentrations of anti-hapten ( dinitrophenyl ) antibodies as signs of polyclonally stimulated antibody synthesis .
C0009498
complement
C0229671
serum