since serine could be interconvertible intramitochondrially to glycine , and because the latter with succinate are the first reactants in heme biosynthesis which is initiated inside the mitochondria , it would appear that erythroid cell sensitivity to cap is predetermined by the mitochondrial glycine-serine pool and might be somehow related to the pathway of heme biosynthesis in these cells .
C0026237
mitochondrial
C0007634
cells