endothelium-derived relaxing factor is released spontaneously and in response to flow , platelet-derived products ( that is , serotonin , thrombin and adenosine diphosphate ) and certain autacoids ( that is , acetylcholine , bradykinin , histamine , substance p , vasopressin , alpha-adrenergic agonists ) .
C0036751
serotonin
C0037343
autacoids