significantly fewer patients treated with acyclovir within the first three days after the onset of exanthem had complications of zoster , as compared with patients treated with placebo ( p = 0.02 by fisher 's exact test ) , but acyclovir also stopped progression of zoster in patients treated after three days of rash ( p = 0.05 by fisher 's exact test ) .
C0001367
acyclovir
C0019360
zoster