in order to analyze the role of the transmembrane-charged amino acids in the association and cell surface expression of the tcr.cd3 complex , we have carried out site-directed mutagenesis of lys271 in the transmembrane domain of the tcr beta chain and analyzed the capacity of the altered chain to assemble in a tcr beta-negative t-cell line .
C0034790
tcr
C0039194
t-cell