to evaluate the analgesic efficacy of a controlled-release morphine sulfate preparation , ms contin tablets ( msc , purdue frederick , toronto , ontario , canada ) , after a single dose and under steady-state conditions , the authors compared msc administered every 12 hours with morphine oral solution ( mos ) administered every 4 hours in 17 adult cancer patients with chronic severe pain .
C0029040
ontario
C0006823
canada