this finding is discussed in relation to the possible oncogenesis of aml , which in this case may mean that the deletion of chromosome # 8 at band 8q22 and the resultant loss of genetic material with possible antioncogenic activity is the critical event leading to malignant transformation in aml and not the translocation of the end of 21q next to 8q .
C1515459
8q22
C1515445
8q