the nature of the benzo [ a ] pyrene-metabolite-deoxyribonucleoside adducts formed was markedly dependent on the nature of the activation system using . systems where cellular integrity is preserved , namely mouse skin in vivo and rat liver hepatocytes and lung explants in vitro , when treated with benzo [ a ] pyrene , formed deoxyribonucleoside adducts of which the major one co-chromatographed with a bay-region diol epoxide-deoxyguanosine adduct , 10 beta- ( deoxyguanosin-n2-yl ) -7 beta , 8 alpha , 9 alpha-trihydroxy-7,8,9,10-tetrahydrobenzo- [ a ] pyrene .
C0011528
deoxyribonucleoside
C0011503
deoxyguanosine