thus , in the intact human heart , digitalis ( 1 ) significantly decreased all measures of ventricular myocardial refractoriness , ( 2 ) had no significant effect on retrograde conduction and refractoriness of the his-purkinje system , and ( 3 ) widened the zone of reentry within the his-purkinje system due to shortening of the functional refractory period of the ventricular muscle with attainment of longer v2-h2 delays .
C0086418
human
C0919509
h2