a methylcholanthrene-induced fibrosarcoma model in c3h/hej mice demonstrated that combined chemoimmunotherapy , including partially purified , 1-butanol-extracted , tumor-specific transplantation antigen ( 1 microgram ) , cyclophosphamide ( 20 mg/kg ) , and continuous intrasplenic ( is ) or intravenous ( iv ) infusion of purified human interleukin-2 ( il-2 ) ( 120 u/d ) reduced the outgrowth of 4-mm established tumors , while il-2 alone only modestly decreased tumor growth .
C0086418
human
C0021756
il-2