treatment of cells with mrna or protein synthesis inhibitors ( alpha-amanitin and cycloheximide ) prolonged coupling to a similar extent as did treatment with 8-brcamp . alpha-amanitin blocked transcription of gap junction mrna , but levels of cytoplasmic mrna encoding the 27-kda gap junction protein were maintained , presumably by block of transcription of an mrna degrading factor .
C0007634
cells
C0010834
cytoplasmic