when these cells were stimulated with beta- [ ( 3 ) h ] estradiol , the mg ( 2+ ) -soluble fraction showed a significant enrichment in chromatin-bound estradiol receptor : the mg ( 2+ ) -soluble mononucleosomes showed a 3- to 4-fold enrichment and the di- and trinucleosomes , a 7- to 19-fold enrichment , when compared to the corresponding subunits in the mg ( 2+ ) -insoluble chromatin fraction .
C0007634
cells
C0008546
chromatin