since it is unknown if chemicals which are generally safe in pregnancy can potentiate the embryotoxicity of cytotoxic drugs before implantation , the combined effects of cyclophosphamide ( cpa ) and caffeine ( cf ) were studied in the mouse ( day 2 ) with cpa at 20 mg/kg , which induces a 18 % resorption rate , and cf at 100 mg/kg , which does not increase embryolethality .
C0032961
pregnancy
C0010583
cpa