two classes of infected cells , with different distributions throughout the liver , were distinguished : ( i ) cells containing a low copy number of double-stranded hbv nucleotide sequences , confined to the cell nucleus and thought to represent hbv dna , and ( ii ) cells containing large amounts ( estimated to be greater than 10 or 15 genome copies per cell ) of hbv dna , much of it in a single-stranded form and largely confined to the cell cytoplasm ;
C0007634
cell
C0010834
cytoplasm