we found that the six drugs , i.e. , daunorubicin ( dnr ) , doxorubicin ( dox ) , rubidazone ( rbz ) , detorubicin ( det ) , n-l-leucyl-dnr ( leu-dnr ) and n-l-leucyl-dox ( leu-dox ) , accumulate at various levels in the cardiac tissue and are metabolized to different extents , leading to the appearance in the heart of variable amounts of dnr or dox .
C0011015
dnr
C0013089
dox