to determine functional subcellular loci of p53 , a cellular protein associated with cellular transformation , we analyzed the nucleoplasmic , chromatin , and nuclear matrix fractions from normal mouse 3t3 cells , from methylcholanthren-transformed mouse ( metha ) cells , and from various simian virus 40 ( sv40 ) -transformed cells for the presence of p53 .
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nucleoplasmic
C0007634
cells