the alpha-adrenergic antagonist phentolamine and the beta-adrenergic antagonist propranolol , given intravenously , had no effect on exogenously administered pge2 , but both antagonists reduced the flare response to infrared irradiation which is supposed to exert its effect via endogenous prostaglandin release .
C0012472
pge2
C0033554
prostaglandin