we find that ( i ) the number of clones found in the peritoneum ( a major tissue source of ly-1 b cells ) decreases with age till mono- or biclonality is common by approximately 6 months , ( ii ) many clones from different mice show the same size rearrangements at both the ig heavy and light chain loci and ( iii ) the igh rearrangements found in a clone isolated from the spleen of one mouse are a subset of those found in the peritoneum of the same mouse , implying migration occurs from the peritoneum to the spleen .
C0007634
cells
C1708726
loci