we wish to report that pretreatment of mer+ cells ( ht-29 human colon carcinoma cells and imr-90 normal human fibroblasts ) with the dna methylating agent mnng , under conditions which should inactivate o6-methyl-transferase , apparently saturates the monoadduct repair system , and allows cnu to form interstrand crosslinks in these cells .
C0016030
fibroblasts
C0007634
cells