the svk14 cell line developed by taylor-papadimitriou et al can serve as a model for study of the modification of various cellular processes by certain pharmacologic and physiologic agents , because these cells resemble normal keratinocytes with respect to a variety of parameters related to proliferation and differentiation , as follows : the svk14 cells show the same ability to form ionophore-induced cross-linked envelopes that is strongly suppressed when the calcium level in the culture medium is reduced .
C0007589
differentiation
C0007634
cells