however , stimulation of pcpa ( 200 mg/kg ) pretreated animals did not significantly increase 5-h1aa either 24 or 72 h after administration of the drug.3 pretreatment of rats with pcpa ( 200 mg/kg ) increased striatal synaptosomal uptake of [ ( 3 ) h ] -5ht by 30 % and reduced 5-ht concentration in the rest of the brain by 62 % .4 pcpa ( 150 mg/kg ) markedly reduced the acute behavioural response ( -76 % ) to p-chloroamphetamine ( 10 mg/kg ) although brain 5-ht was only moderately reduced ( -36 % ) .
C0086045
concentration
C0006104
brain