only one ( 2 % ) of 57 subjects taking trimethoprim-sulfamethoxazole ( 160 mg/800 mg daily ) experienced diarrhea during a two-week study , whereas eight ( 14 % ) of 58 subjects taking trimethoprim alone ( 200 mg daily ) and 10 ( 33 % ) of 30 taking placebo developed illness ( p less than .05 and p less than .0001 , respectively ) .
C0041044
trimethoprim-sulfamethoxazole
C0041041
trimethoprim