cell fractionation and crossover reconstitution assays of adherent ( adh ) and nonadherent ( nad ) splenocyte populations from vehicle and casein-treated mice indicated that : 1 ) adh splenocytes from casein-treated mice were responsible for suppression of humoral responses , 2 ) nad splenocytes from casein-treated mice reconstituted with vehicle or naive adh cells abrogated the immunosuppression , and 3 ) suppression of humoral responses in cultures containing casein adh splenocytes was due to this cell populations inability to function as accessory cells in humoral responses rather than induction of suppressor macrophages .
C0007634
cell
C0007613
function