eight patients who improved their exercise duration to angina or marked fatigue ( greater than or equal to 25 % ) on timolol 10 to 30 mg twice daily over that on placebo 8 to 14 mo previously were subjects in a double-blind , randomized , crossover 4-wk study of the effect of timolol on exercise duration 2 and 12 hr after medication .
C0002962
angina
C0040233
timolol