the inhibition of lung colonization in c57bl/6 mice by rtimp is one of the first examples showing an antimetastatic effect of a selective metalloproteinase inhibitor in a mammalian animal model , and supports an essential role for metalloproteinase ( s ) in the extravasation and invasion of tumor cells during lung colonization by blood-borne tumor cells .
C0024109
lung
C0024121
lung