from the first report of the efficacy of the iodides for the treatment of sporotrichosis ( 1903 ) until the introduction of the imidazoles ( azoles , 1960s ) , the number of antifungal agents available was very limited , including griseofulvin ( 1939 ) , nystatin ( 1950 ) , amphotericin b ( 1956 ) , and flucytosine ( 1964 ) .
C0003308
antifungal agents
C0016278
flucytosine