we conclude that urinary excretion of hypoxanthine and xanthine increases dramatically whereas uric acid excretion rises moderately in children undergoing tumor lysis while receiving allopurinol , that acute renal failure occurs in children with a higher purine load per deciliter of glomerular filtrate , but that factors other than tubular precipitation of purine metabolites are likely to be involved in the pathogenesis of renal failure during tumor lysis .
C0002144
allopurinol
C0034140
purine