although impairment of t-cell or nk-mediated anti-tumor responses by using 400 r 60co-irradiated or balb/c nude ( nu/nu ) mice suggested that certain immunologic responses were not effective in preventing experimental metastasis , impairment of macrophage function with chlorine , silica , trypan blue , carrageenan , cyclophosphamide or pristane were effective and resulted in enhanced malignancy of the parental raw117 line .
C0027651
tumor
C0006826
malignancy