studies reported in this paper have demonstrated that administration of phenobarbital ( 0.05 % in the diet ) for 6 months following a single dose of diethylnitrosamine ( 5 to 10 mg/kg ) given within 24 hours after partial hepatectomy resulted in a marked increase in the number of enzyme-altered foci in the liver as well as in the production of hepatocellular carcinomas .
C0193398
partial
C0023884
liver