the toxicology studies indicated that the maximal tolerated dose of free amphotericin b was 0.8 mg/kg of body weight and the 50 % lethal dose ( ld50 ) was reached at 1.2 mg/kg , while neither the maximal tolerated dose nor the ld50 for the liposomal amphotericin b was reached at a dose of 12 mg/kg .
C0002679
amphotericin b
C1145701
liposomal amphotericin b