in rats with renal failure produced by excision of one kidney and infarction of large portions of the other kidney , given a low calcium , high phosphorus diet for 2-3 weeks , gfr was reduced by 80 percent , the fractional excretion of sodium increased from 7 to 23 percent , that of bicarbonate from 16 to 23 percent and that of water from 4 to 13 percent .
C0035078
renal failure
C0022646
kidney