the oligonucleotide blocks , synthesised enzymatically by means of ribonucleases of various substrate specificity and polynucleotide phosphorylases ( tpupc , apupcpc , pgptpupc , gpapupcpc ) or obtained by hydrolysis of poly ( u ) and poly ( a ) with serratia marcescens endonuclease ( hexauridilate and hexaadenilate ) , were joined by t4 rna ligase .
C0035542
ribonucleases
C0020291
hydrolysis