as the observed infection rate when metronidazole was given at the start of operation was seven-fold that previously found in the same department when 1 g metronidazole was administered 3-4 hours preoperatively ( 28/103 vs. 2/50 , p less than 0.01 ) , the timing of metronidazole prophylaxis was assumed to be potentially important for its ability to protect also against aerobic postoperative infection .
C0009450
infection
C0392618
postoperative infection