the following effects were observed : ( 1 ) a marked rise in plasma alpha-hanp , ( 2 ) a progressive fall in bp ( from 181/127 to 165/109 mmhg ) and plasma volume , ( 3 ) a probably baroreflex-mediated sympathetic activation , evidenced by raised heart rate and plasma norepinephrine levels , ( 4 ) an increase in serum free fatty acids and circulating insulin ( +45 % ) , ( 5 ) an enhanced diuresis ( +770 % ) and excretion of sodium ( +665 % ) , chloride ( +524 % ) , phosphate ( +518 % ) , other electrolytes , amino acids and free water clearance , ( 6 ) biphasic responses in the glomerular filtration rate ( gfr ) and p-aminohippurate ( pah ) clearance , with initial increases ( +40 and 30 % , respectively ) followed by a rapid return to ( gfr ) , or even a fall below ( pah clearance ) control values , and ( 7 ) a marked rise in the filtration fraction .
C0032105
plasma
C0229671
serum