the mean serum concentration of cbz is lower when the drug is given in combination with phenytoin ( 59.4 % ) , primidone ( 58.2 % ) , phenobarbital ( 65.7 % ) , and valproate ( 83.0 % ) than when cbz is given alone ( 100 % ) , whereas the mean concentration of cbz-epoxide is increased by valproate ( 144.8 % ) , by primidone ( 118.5 % ) , and by a combination of the latter ( 167.4 % ) .
C0031412
phenobarbital
C0033148
primidone