these data suggest that : ( a ) somatostatin is synthesized in fundic d cells primarily as s14 , ( b ) s14 is produced by rapid processing of a larger precursor but there is little , if any , conversion of s28 to s14 , ( c ) somatostatin biosynthesis is autoregulated , and ( d ) newly synthesized s14 is preferentially released from d cells in response to stimulation .
C0074854
s28
C0037659
s14