taken together , our results suggest that : 1 ) pkc plays an important role in the transduction of activating signals for m phi activation by maf and a23187 to mediate cytotoxicity against some ( p815 ) but not other ( ns-1 ) tumor cells , 2 ) the induction of tnf-alpha mrna expression and tnf secretion may be achieved via a pkc-independent pathway , and 3 ) m phi are equipped with more than one signal transduction pathways for affecting distinct functional activities .
C0037083
transduction
C0033634
pkc