the influence of cyclic amp on cartilage degradation was investigated by using phosphodiesterase inhibitors [ theophylline and 3-isobutyl-1-methylxanthine ( ibmx ) ] , forskolin ( which activates the catalytic subunit of adenylate cyclase ) and cyclic amp analogues ( dibutyryl and 8-bromo ) .
C0039771
theophylline
C0000096
3-isobutyl-1-methylxanthine