when the 1,4-dihydropyridine ca2+-channel blocker nifedipine ( 1 microm ) was incubated with synaptosomes for 1 min , there was a 17.0 % decrease in [ ca2+ ] i and when it was combined with either u-50,488h ( 1 microm ) or clonidine ( 1 microm ) there was a reduction in [ ca2+ ] i of 35.0 and 48.1 % respectively i.e . the effects were additive .
C0012315
dihydropyridine
C0028066
nifedipine