to determine whether pharmacological control of blood pressure could affect the renal function and its deterioration in shr with renal ablation , we studied effects of oral administration of captopril ( 50 mg/kg/day ) and ramipril ( 10 mg/kg/day ) , angiotensin converting enzyme inhibitors ( acei ) , nilvadipine ( 10 mg/kg/day ) and benidipine ( 3-6 mg/kg/day ) , calcium channel blockers ( ccb ) , and indapamide ( 10 mg/kg/day ) , a non-thiazide diuretic , for 2 and 12 weeks on systolic blood pressure ( sbp ) , blood urea nitrogen ( bun ) and serum creatinine ( scr ) , endogenous creatinine clearance ( ccr ) , and urinary protein excretion ( up ) in shr subjected to 5/6 nephrectomy a week before .
C0022646
renal
C0027695
nephrectomy