analysis of the changing distribution of origin site of 1,990 colorectal cancers observed at a large midwestern hospital shows a statistically significant trend of a decreasing percentage of distal ( rectum , p=.0192 ) and an increasing percentage of proximal ( cecum , p=.0015 ) large-bowel lesions during a period of at least 30 years .
C0007531
cecum
C0021851
large-bowel