sindbis virus obtained after passage on human fibroblasts from patients with i-cell disease ( mucolipidosis ii ) and called i-cell virus differed from sindbis virus obtained from chick fibroblasts or from normal human fibroblasts in two ways : ( 1 ) the i-cell virus was extremely unstable to freezing and thawing , ( 2 ) the i-cell virus showed greatly exaggerated sensitivity to inactivation by triton x-100 .
C0016030
fibroblasts
C0007634
cell