we have previously shown that a 10-min intravenous infusion of 6-iodo-amiloride , an analogue of the sodium channel blocker amiloride , causes a sustained decrease in blood pressure in two genetic models of hypertension , spontaneously hypertensive rats ( shr ) and dahl salt-sensitive ( ds ) rats .
C0002502
amiloride
C0020538
hypertension