our results demonstrated a reversible inhibition of cerebral sulfate transferase activity ( p less than 0.001 or less than 0.01 ) and to a lesser extent ( p less than 0.001 or ns ) of dna synthesis in brain cell cultures by the highest concentrations studied of amikacin , cefuroxime , and ceftazidime which correspond to peak cerebrospinal fluid values attained by intraventricular therapy in patients .
C0006104
brain
C0086045
concentrations