it is proposed that sulphur-containing radicals resulting from attack of biologically-produced oxidants upon penicillamine in the presence of o2 can themselves inactivate alpha 1-antiproteinase , and that such radicals might contribute to the side-effects produced by penicillamine or gold thiol therapy in rheumatoid arthritis .
C0030817
penicillamine
C0003873
rheumatoid arthritis