coagulation factor v ( fv ) is a single-chain glycoprotein ( mr 330,000 ; domain structure a1-a2-b-a3-c1-c2 ) that is activated to factor va ( fva ; mr 174,000 ) by thrombin , which cleaves away the b domain leaving a heterodimeric structure composed of a heavy chain ( a1-a2 ; mr 94,000 ) and a light chain ( a3-c1-c2 ; mr 74,000 ) .
C0015498
coagulation factor v
C0015501
factor va