in 1986 , 275 seronegative mentally handicapped residents were vaccinated intramuscularly in the deltoid region with 20 micrograms ( 1.0 ml ) of a recombinant deoxyribonucleic acid yeast-derived hepatitis b vaccine ( engerix-b , smithkline biologicals , rixensart , belgium ) on a zero- , one- , six-month schedule .
C0062527
recombinant
C0116078
engerix-b