when permeability to both k+ and h+ was increased ( e.g using valinomycin plus a protonophore or nigericin ) , stimulation of k+-atpase was much less dependent on the anion and the observed dissipation of the vesicular ph gradient was consistent with an 'uncoupling ' of atp hydrolysis from h+ accumulation .
C0001473
atpase
C1510699
atp hydrolysis