this interface of urine and transitional epithelium may be clinically important in many urologic disease states , since a malfunction of this layer could be involved in a spectrum of urologic diseases that includes irritable bladder syndromes ( e.g. , detrusor instability , interstitial cystitis , urethritis , radiation cystitis , cyclophosphamide-induced cystitis ) , carcinoma in situ , calculus disease , infections , and even carcinogenesis .
C0042075
urologic diseases
C0010692
cystitis