measurements were made of the activities of the four key enzymes involved in gluconeogenesis , pyruvate carboxylase ( ec 6.4.1.1 ) , phosphoenolpyruvate carboxylase ( ec 4.1.1.32 ) , fructose 1,6-diphosphatase ( ec 3.1.3.11 ) and glucose 6-phosphatase ( ec 3.1.3.9 ) , of serine dehydratase ( ec 4.2.1.13 ) and of the four enzymes unique to glycolysis , glucokinase ( ec 2.7.1.2 ) , hexokinase ( ec 2.7.1.1 ) , phosphofructokinase ( ec 2.7.1.11 ) and pyruvate kinase ( ec 2.7.1.40 ) , in livers from starved rats perfused with glucose , fructose or lactate .
C0017715
gluconeogenesis
C0017725
glucose