such cells , now routinely cultured in our laboratory from tissue obtained at the time of reduction mammoplasty , were used to study the actions of estradiol ( e2 ) , the progestin promegestone ( r5020 ) , and the antiprogesterone ru486 on cell growth and progesterone-dependent 17 beta-hydroxysteroid dehydrogenase ( e2dh ) activity , which is considered good marker of epithelial differentiation as well as progesterone dependency .
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cells
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the