nevertheless , because ila pi 4.8 retains the full spectrum of igf bioactivities in vitro , and significant quantities are present in normal human serum ( 21 % ) , it would suggest that proteolytic conversion of igf-i , somatomedin a and igf-ii to ila pi 4.8 in vivo may be a physiologically significant event .
C0037657
igf
C0021666
igf-ii