because thiazides and beta-blockers have adverse effects on lipoproteins , while magnesium repletion ( shown to occur with amiloride ) and beta 2 agonists improve lipids , we studied the effects of 3 months each of amiloride with and without salbutamol with and without placebo in a 2 x 2 factorial crossover study in which all patients took timolol-hydrochlorothiazide twice daily for 1 year .
C0023820
lipoproteins
C0023779
lipids