these include the activities in vitro ( 1 ) catalyzing adp-ribosylation of one of the membrane proteins directly , ( 2 ) enhancing membrane adenylate cyclase activity in c6 cells , ( 3 ) reversing receptor-mediated inhibition of insulin or glycerol release from pancreatic islets or adipocytes , respectively , and the activities in vivo ( 4 ) inhibiting epinephrine-induced hyperglycemia , ( 5 ) potentiating glucose-induced hyperinsulinemia , ( 6 ) reducing hypertension and increasing the heart rate in genetically hypertensive rats .
C0021641
insulin
C0022131
pancreatic islets