relatively high concentrations of mk-733 ( simvastatin ) and mk-803 ( lovastatin , mevinolin ) , which are 3-hydroxy-3-methylglutaryl coenzyme a ( hmg-coa ) reductase inhibitors , were found to inhibit acyl coenzyme a : cholesterol acyltransferase ( acat ) of rabbit intestinal microsomes with ic50 's of 2.0 x 10 ( -5 ) and 3.6 x 10 ( -5 ) m , respectively .
C0074554
simvastatin
C0024027
mevinolin