in order to delineate the sequence of development of the metabolic changes in the obese-hyperglycaemic syndrome in the nzo mouse , the uptake of 2-deoxyglucose , glucose utilization and glycogen synthesis by isolated soleus muscle in the absence and presence of graded doses of insulin was measured , and related to the gain in body weight and development of hyperinsulinaemia and hyperglycaemia .
C0017725
glucose
C0020456
hyperglycaemia