in rats , the sleeping time induced by overdosage with eight steroid anesthetics -- alfathesin , 3- ( 3-oxo-17beta-hydroxy-19-nor-4-androsten-17alpha-yl ) -propionic acid-lactone ( sc-8109 ) , 21-hydroxy=5alpha-pregnane-3,20-dione ( p-234 ) , 4-pregnene-3,11,20-trione ( bio.66 ) , 17-hydroxy-3-oxo-4-androstene-17alpha-propionic acid-gamma-lactone ( sc-5233 ) ,3alpha-hydroxy-5beta-pregnane-11,20-dione , 5beta-pregnane-3,11,20-trione ( u-1373 ) , and hydroxydione -- was abolished or considerably reduced by a variety of catatoxic compounds , particularly 3beta-hydroxy-20-oxo-5-pregnene-16alpha-carbonitrile ( pcn ) , 9alpha-fluoro-11beta,17-dihydroxy-3-oxo-4-androstene-17alpha-propionic acid potassium salt ( cs-1 ) , prednisolone , ethylestrenol and spironolactone .
C0038317
steroid
C0033006
pregnane