cells from gardner 's syndrome ( gs ) and familial polyposis coli ( fp ) patients , persons with a hereditary predisposition to colon cancer , were compared to those of normal persons for sensitivity to the cytotoxic and mutagenic action of n-methyl-n'-nitro-n-nitrosoguanidine ( mnng ) , a model compound chosen because methylating agents have been implicated in colon carcinogenesis .
C0007634
cells
C0032580
familial polyposis coli