after 8 weeks of therapy ( 100 mg doses given to 31 in the metoprolol group and 43 in the atenolol group ) , clinical bioequivalence according to stated definition was found for blood pressures and heart rate reductions , although the reductions of systolic and diastolic blood pressures at rest as well as diastolic blood pressure during exercise were significantly greater in the metoprolol group .
C0004147
atenolol
C0428977
heart rate reductions