for children living in an endemic malarious area , a single dose of mefloquine 7.1-12.5 mg/kg , given in combination with sulfadoxine ( 14.3-25.0 mg/kg ) and pyrimethamine ( 0.7-1.3 mg/kg ) , is a safe and effective treatment for uncomplicated chloroquine-resistant plasmodium falciparum malaria .
C0008269
chloroquine
C0024535
plasmodium falciparum malaria