although morphine administration alone in general did not significantly affect ach content and turnover in specific brain areas , morphine administered prior to tbi either prevented injury-induced changes in ach turnover ( dorsal pontine tegmentum ) or actually reduced the rate constant for ach utilization ( kach ) and the turnover rate of ach ( trach ) following injury ( thalamus , amygdala , cingulate/frontal cortex , and hippocampus ) .
C0423896
content
C0006104
tbi