a single dose of 9-hydroxy-ellipticine , 2-n-methyl-9-hydroxy-ellipticine , 9-fluoro-ellipticine , and 9-amino-ellipticine ( 5 to 10 mg/kg body wt , ip ) resulted in murine bone marrow toxicity as shown by chromosome clumping , chromatid aberrations , and micronuclei formation .
C0008633
chromosome
C0008545
chromatid