though there was a significant ( p less than 0.01 ) reduction of the heart rate of 26 % by metoprolol ( m ) and of 21.2 % by pindolol ( p ) , the o2-uptake during submaximal work was unchanged under p with 1.66 +/- 0.4 l/min and under m with 1.7 +/- 0.44 l/min in comparison with the control ( c ) of 1.71 +/- 0.38 l/min .
C0428977
reduction
C0031937
pindolol