since the hotf-binding element is similar to the upstream promoter sequence ( ups ) of the adenovirus 2 major late promoter ( ad2mlp ) , we examined whether rat hotf is homologous to the upstream stimulatory factor ( usf ) or major late transcription factor previously identified in hela cells , which interacts with the ups and activates the transcription from the ad2mlp .
C0040648
hotf
C0076925
upstream stimulatory