under conditions of an outwardly directed oh- gradient , dids-sensitive folate uptake was cis inhibited ( greater than 90 % ) by reduced folate analogues : dihydrofolate ( ic50 = 0.40 microm ) , folinic acid ( ic50 = 0.50 microm ) , 5-methyltetrahydrofolate ( ic50 = 0.53 microm ) , and ( + ) amethopterin ( ic50 = 0.93 microm ) .
C3536866
folate analogues
C0023413
folinic acid