we have tested various carbohydrate structures and neoglycoproteins ( carbohydrate haptens attached to bsa ) as inhibitors of the invasion of human red blood cells by plasmodium falciparum merozoites ( strain fcb ) in synchronous in vitro cultures , using 3h-hypoxanthine incorporation into intraerythrocytic parasites as analytical tool , and have got the following results : the inhibition rate of n-acetyl-d-glucosamine glycosides is increased with increasing lipophilicity of the aglycon or spacer : ch3 less than ( ch2 ) 2nhco ( ch2 ) 2cooch3 less than ( ch2 ) 8cooch3 ;
C0007004
carbohydrate
C0017977
glycosides