out of 72 pregnancies correctly classified by the amniotic-fluid alpha-fetoprotein ( a.f.p . ) test , 2 of 56 without neural-tube defects and all 16 with open neural-tube defects ( 8 with anencephaly and 8awith open spina bifida ) had raised levels of ache .
C0027794
neural-tube defects
C0002902
anencephaly