using circular dichroism ( cd ) , it was found that when codissolved in trifluoroethanol ( tfe ) , after drying and subsequent hydration , gramicidin is mainly present in the single-stranded beta 6.3-helical configuration , whereas when using chloroform/methanol or ethanol as the solvent , it is proposed that the dominant conformation of gramicidin in the membrane is that of the double-stranded antiparallel dimer .
C0001963
methanol
C0001962
ethanol