since its proximate carcinogenic metabolite , n-hydroxy-2-na , was known to react directly with dna in vitro to give specific carcinogen-base adducts , we investigated the in vivo formation and persistence of ( 2-na ) -dna adducts in the bladder and liver and attempted to determine whether or not these lesions correlated with tissue susceptibility .
C0012854
dna
C0242958
dna adducts