these results indicate that inherent cellular properties , not associated with gross differences in ra uptake or metabolism , primarily determined the relative sensitivity or insensitivity of hl-60 cells to ra-induced differentiation but that ra responsiveness was markedly regulated by extracellular factors , one of which , serum albumin , appeared to act by decreasing the initial cell association and metabolism of ra , whereas other , as yet unidentified exogenous factors , may have acted independently of these functions .
C0007634
cellular
C0007589
differentiation