we studied expression of contractile actin isotypes by measuring mrna levels in total cellular rna purified from right ( rv ) and left ventricles ( lv ) of calves with severe pulmonary hypertension after a 2-wk exposure to hypobaric hypoxia and age-matched controls . alpha-skeletal actin mrna was increased greater than 10-fold in the rv of hypertensive animals , whereas alpha-cardiac actin mrna did not appear to change . alpha-skeletal actin mrna and alpha-cardiac actin mrna did not increase in the lv of any of the hypoxic animals .
C0026820
contractile
C0001271
actin