a hypothesis concerning the mechanism whereby chloroquine phosphate and hydroxychloroquine sulfate are therapeutically active in rheumatoid arthritis is presented , based on in vitro data that ( 1 ) utilize drug concentrations not higher than those clinically achievable , and ( 2 ) might explain mechanisms that may be applicable in treated rheumatoid arthritis patients .
C0596007
hydroxychloroquine sulfate
C0003873
rheumatoid arthritis