for instance in a gram-positive infection , inflammatory cells may be activated to produce endogenous pyrogen at the site of bacterial multiplication by any or all of the following mechanisms , most of which have been demonstrated experimentally : phagocytosis of bacteria , chemotactic factors produced by bacteria or released from injured tissue of complement activation , immune reactions ( either cellular or antibody-mediated ) in a previously sensitized host , and toxins , e.g . endotoxins which may activate phagocytic cells directly .
C0031308
phagocytosis
C0031307
phagocytic cells