next , to investigate the effect of t cells derived from a gut-associated lymphoid tissue ( galt ) , mesenteric lymph nodes ( mln ) , as well as from spleen on terminal differentiation of postswitch siga pp b cells , lps-driven pp b cells were precultured with the cloned t cells to induce a switch to siga , and subsequently cultured with mln or spleen t cells or a lyt-2+-depleted t cell subset in the presence of a t-dependent polyclonal mitogen , staphylococcal protein a .
C1511002
differentiation
C0004561
b cells