to detect nuclear protein factors which might account for a tissue-specific and inducible expression of the rat tyrosine aminotransferase ( tat ) gene promoter , extracts from rat liver and spleen nuclei have been fractionated by heparin-sepharose chromatography and the fractions assayed for sequence-specific binding to the distal tat gene promoter element ( sequence between -313 and -210 ) .
C0028589
nuclear protein
C0007610
nuclei