doxepin-treated subjects experienced fewer lesions ( p less than 0.001 ) , less waking hours with lesions ( p less than 0.01 ) , lesser degree of itch and/or discomfort ( p less than 0.001 ) , and less swelling or angioedema ( p less than 0.001 ) as compared to placebo-treated subjects .
C0013085
doxepin
C0033774
itch