in the kidneys of streptozotocin-injected mice , the concentration of succinyl-coa was increased , that of citrate and guanosine 5'-triphosphate was decreased , that of glucose 6-phosphate , fructose 6-phosphate and fructose 1,6-diphosphate was unaffected , and the metabolite concentration ratios suggested increased mitochondrial [ nad+ ] / [ nadh ] ratio and decreased cytoplasmic [ nad+ ] / [ nadh ] ratio .
C0026237
mitochondrial
C0010834
cytoplasmic