molecular cloning has defined two types of natriuretic peptide receptors : the anp-c receptor of relative molecular mass ( mr ) 60-70,000 ( 60-70 k ) , which is not coupled to cgmp production and may function in the clearance of anp and the anp-a receptor of mr 120-140 k , which is a membrane form of guanylate cyclase in which ligand binding to the extracellular domain activates the cytoplasmic domain of the enzyme .
C1529723
anp-a
C0018358
guanylate cyclase