polymorphonuclear leukocytes ( pmn ) from ten patients with chronic stable plaque psoriasis , five of whom had more than 40 % skin involvement and five with less than 20 % involvement , responded in a dose-related fashion to stimulation with the arachidonic acid lipoxygenase products 5- and 12-hydroxyeicosatetraenoic acid ( 5- and 12-hete ) and leukotriene b4 ( ltb4 ) in an in vitro chemokinesis assay .
C0014518
ten
C1511567
skin involvement