we have demonstrated : ( 1 ) bone mass in this sample of juvenile diabetics is depressed , without evidence of impaired overall growth or delayed maturation , ( 2 ) this reduced bone mass probably results from a failure to gain the normal component of endosteal bone expected at this age , ( 3 ) this abnormality in bone growth progresses with disease but does not appear to vary with serum glucose control , and ( 4 ) in this population of diabetics there is a minimal but significant reduction in serum total and ionized calcium and serum magnesium without compensatory elevation of parathyroid hormone .
C0262950
bone
C0005941
abnormality