immunohistochemical studies , using anti-rat spleen prostaglandin d synthetase antibody and the immunoperoxidase method , showed that prostaglandin d synthetase was localized in langerhans cells ( not in keratinocytes ) in the epidermis , in macrophages or histiocytes , and also in mast cells in the dermis .
C0023005
langerhans cells
C0014520
epidermis