it is suggested , therefore , that corneal opacity due to befunolol hydrochloride topically administered to the eye , is concerned mainly with the epithelium in cornea , since the drug is uncapable of passing barrier probably existing in surface layer of epithelium but it easily penetrates in corneal layers from endothelial side to attain reversely to epithelial cells .
C0014609
epithelium
C0014597
epithelial cells