while the selective anti-herpes agents ( e ) -5- ( 2-bromovinyl ) -durd , ( e ) -5- ( 2-chlorovinyl ) -durd , ( e ) -5- ( 2-iodovinyl ) -durd , ( e ) -5- ( 3,3,3-trifluoro-1-propenyl ) -durd and ( e ) -5- ( 1-propenyl ) -durd did not induce sce unless their concentration was about 1000-5000-fold greater than that required to inhibit herpes-virus replication , several other durd analogues such as 5-vinyl-durd , 5-ethynyl-durd , 5-formyl-durd , 5-hydroxymethyl-durd and 5-trifluoromethyl-durd induced sce at a concentration closely corresponding to those required to inhibit either virus replication or tumour-cell growth .
C0037211
sce
C0007634
cell