in an effort to determine whether the natural history and clinical course may be different , with implications relevant to prophylaxis against opportunistic infections , we have documented the clinical courses of the first 24 known cases of acquired immunodeficiency syndrome ( aids ) in women in rhode island , most of whom developed centers for disease control-defined aids before the availability of an effective antiviral agent ( i.e. , zidovudine ) or a well-defined approach to prophylaxis against opportunistic infections ( e.g. , oral trimethoprimsulfa ) .
C0001175
aids
C0043474
zidovudine