in another lung disease , emphysema , pulmonary granulocytes ( pmns ) are thought to be doubly responsible for lung dissolution : they release potent proteolytic enzymes including elastase , and they generate reactive oxygen species that oxidize a reactive site methionine group in alpha-1-protease inhibitor ( alpha-1-pi ) rendering it , in turn , impotent as an anti-elastase .
C0024115
lung disease
C0024109
lung