the circular dna is resistant to the action of escherichia coli exonuclease iii and t7 exonuclease , but becomes sensitive to these nucleases after treatment with pronase showing the presence of a protein that binds non-covalently to the ends of the dna to circularize it as well as protect it from digestion with exonucleases .
C0012925
circular dna
C0012854
dna