with the aim of obtaining new agents for the photochemotherapy of psoriasis , we have prepared monofunctional reagents for dna by starting from 4,5'-dimethylangelicin ( 2 ) , an angular furocoumarin , and introducing in a 4'- ( hydroxymethyl ) ( 3 ) , 4'- ( methoxymethyl ) ( 4 ) , or 4'- ( aminomethyl ) group ( 5 ) , in way analogous to what other authors have done previously on trioxsalen , a dna bifunctional reagent .
C0012854
dna
C0000702
a dna