in order to investigate in more detail the role of the insp3-sensitive ca2+ store in secretion from these cells , we have used a combination of an insp3-mobilizing muscarinic agonist and the sesquiterpene lactone thapsigargin ( tg ) , which releases internal ca2+ without concomitant breakdown of inositol lipids or protein kinase c activation , to examine the events which follow depletion of the releasable ca2+ store in these cells .
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secretion
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cells