these combined results indicate that ( a ) extensive lens fiber junctions and functional cell-to-cell channels are found between differentiated lentoid lentoid cells in vitro , ( b ) lens fiber junctions appear to form during the course of lens cell differentiation in culture , ( c ) a significant increase occurs in the putative junctional protein before the cultures are highly developed , ( d ) the increased levels of mp28 and junction formation may be required for the full expression of the differentiated state in the lens fiber cell , and ( e ) this culture system should prove to be valuable for additional experiments on lens junctions and for other studies requiring the development of lens fiber cells in vitro .
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lens
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of