in pithed spontaneously hypertensive rats , 5-carboxamidotryptamine , 5-ht , and to a lesser extent the 5-ht1 receptor agonist ru 24969 , but not the 5-ht1a receptor agonist 8-oh-dpat , produced depressor responses which were antagonised by methysergide and metitepin , but which do not clearly fit with any of the 5-ht1 ligand binding sites .
C0597357
8-oh-dpat
C1517880
ligand binding