it is suggested that proliferative cells of the peri-portal region , which begin dna synthesis early after partial hepatectomy , have the greatest ability to form clones of atpase-deficient putative pre-neoplastic foci after initiation by a carcinogen and might thus represent , if exposed to carcinogen in early s-phase , the effective target cell population for the induction of hepatocellular carcinomas .
C0227525
cells
C2239176
hepatocellular carcinomas