this , together with the observed focal uniformity of maturation found in bone marrow , and the periodicity of the fluctuations of the neutrophils in the peripheral blood , leads to the formulation of the hypothesis of a constant functional withdrawal of granulocytes from the peripheral blood with a periodic delivery of new cells from the marrow , which in leucopenia and in leucocytosis represents a depression or a stimulation , respectively , of the normal mechanism .
C0229664
peripheral blood
C0005773
peripheral blood