it has been postulated that 3- ( 3-oxo-7alpha-methylthio-4-androsten-17alpha-yl ) propionic acid gamma-lactone ( i ) is a key intermediate in the metabolism of the anti-aldosterone agent , spironolactone ( 3- [ 3-oxo-7alpha-acetylthio-17beta-hydroxy-4-androsten-17alpha-yl ] propionic acid gamma-lactone ) .
C0037982
spironolactone
C0022947
lactone