it is suggested that insulin is essential for the induction and maintainance of l-pyruvate kinase activity , that carbohydrates in the absence of insulin are unable to maintain the enzyme activity in cultures of hepatocytes , and that insulin and glycolytic metabolites may act synergistically to increase the activity of l-pyruvate kinase by increasing the synthesis of the enzyme .
C0021641
insulin
C0017952
glycolytic