after intravenous administration of aminophylline equivalent to 10 mg kg-1 theophylline , the average mean residence time ( mrt ) was 58 per cent higher in the protein-deficient rats , while the total plasma clearance ( cl ) per kilogram of body weight and elimination rate constant ( k ) were decreased by 39 per cent and 45 per cent , respectively , when compared to rats on a normal protein diet .
C1335665
protein
C0034693
rats