young adult diabetic patients with cystic fibrosis have total loss of exocrine pancreas with fat replacement , lack of nesidioblastosis , a qualitative decrease in the number of islets , fibrosis of and amyloid deposits in islets , decreased numbers of insulin-containing cells in each islet , and atrophy of islet cells , probably resulting from progressive ischemia .
C0027773
nesidioblastosis
C0022131
islet cells