1 in order to study the relative contribution of hepatic drug metabolizing enzymes and hepatic blood flow to the clearance of drugs in the hyperthyroid state , the disposition kinetics of two model compounds ( antipyrine and propranolol ) were examined in thyroid-fed dogs as compared to euthyroid and phenobarbitone-pretreated animals .
C0020550
hyperthyroid
C0040132
thyroid