a double-blind crossover study to determine the effects on intraocular pressure ( iop ) and blood pressure of topically instilled 0.125 % and 0.25 % solutions of clonidine hydrochloride by comparison with a 2 % pilocarpine hydrochloride solution and placebo was carried out in a total of 21 patients with open-angle glaucoma , each of whom received a single drop of each preparation in the same glaucomatous eye on separate days .
C0017612
open-angle
C0015392
eye