these and earlier results on the stereoselective k-region metabolism studies of 7-methylbenz [ a ] anthracene and 12-methylbenz [ a ] anthracene indicate that cytochrome p-450 isozymes exhibit different stereoselectivities in the k-region epoxidations of ba and dmba and a methyl substituent at the c12 position of ba alters the stereoheterotopic interactions between cytochrome p-450 isozymes and the ba molecule .
C0025519
metabolism
C0010762
cytochrome p-450