the question whether glucose or insulin regulates gluconeogenesis by effecting changes in the fructose-6-phosphate ( f-6-p ) substrate cycle ( phosphofructokinase ( pfk ) , fructose-1,6-diphosphatase ( fdpase ) ) was investigated in vivo in fasted normal rats using [ 3-3h , u-14c ] - or [ 3-3h,6-14c ] glucose .
C0017715
gluconeogenesis
C0017725
glucose