in a study of the effect of guanethidine-induced sympathectomy on the development of hypertension is spontaneous hypertensive rats ( shr , okomoto strain ) , only a partial sympathectomy could be produced as assessed by biochemical parameters ( tyrosine hydroxylase activity in ganglia and tissue norepinephrine concentrations ) and by evaluation of response to stimulation of vasomotor outflow in pithed rat preparations .
C0018318
guanethidine
C0020538
hypertension