we studied the effect of metformin therapy ( 1700 mg daily ) on glucose tolerance , insulin secretion , and insulin binding to monocytes in 10 non-insulin-dependent diabetics ( mean duration of disease 2.6 yr ) who were treated for 4 wk with either metformin or placebo in a double-blind cross-over study .
C0011860
non-insulin-dependent
C0025598
metformin