the strengths and weaknesses of the two hypotheses are compared in relation to the following characteristics of torsade de pointes : facilitation by slow heart rate , suppression by pacing , r on t phenomenon , difficulty of induction by programmed stimulation , aggravation by hypokalemia , manifestation of an idiosyncratic reaction to class ia antiarrhythmic drugs , spontaneous termination , suppression by magnesium salts and isoproterenol and induction by such drugs as sotalol , bepridil and prenylamine .
C0428977
slow heart rate
C0037707
sotalol