both serum insulin and proinsulin decreased ( insulin from 15 +/- 8 to 10 +/- 4 microu/ml , p less than .02 ; proinsulin from 31 +/- 18 to 13 +/- 5 pm , p less than .02 ) , and the molar ratio of proinsulin to insulin also tended to decrease ( from 0.321 +/- 0.08 to 0.24 +/- 0.10 , p less than .10 ) .
C0033362
proinsulin
C0021641
insulin