cells transfected with either the first or second construct and selected for the tk+ phenotype were then tested for tk induction after superinfection with hsv-1 ( f ) delta 305 , containing a deletion in the coding sequences of the tk gene , and viruses containing , in addition , a ts lesion in the alpha 4 regulatory protein ( ts502 delta 305 ) or in the beta 8 major dna-binding protein ( tsha1 delta 305 ) .
C0007634
cells
C0015295
coding sequences