when the interval of exposure to 100 microm 7-oh-mtx was increased to 6 hr , cell growth was inhibited by 60 % and there was mild ( approximately 50 % ) inhibition of purine and thymidylate biosynthesis associated with a small increase in cellular dihydrofolate and a small decline in cellular tetrahydrofolates .
C0007595
cell growth
C0007634
cellular