it is shown that shortly after extracellular free ca2+ concentration is lowered to the micromolar range , the actin-containing , junction-associated belt of microfilaments , together with the vinculin-rich junctional plaque material , is irreversibly detached as one structural unit from the plasma membrane , contracts , and is displaced towards the perinuclear cytoplasm where it gradually disintegrates .
C0007603
plasma membrane
C0010834
cytoplasm