a tentative explanation of the mechanism of interaction in terms of inhibition of renal tubular supplementary spironolactone , involve a tendency to development of hypokalemia , hypochloremia , and alkalosis , it is recommended that supplementary use of bendroflumethiazide in this setting is combined with the administration of potassium chloride or potassium-saving diuretics .
C0037982
spironolactone
C0020621
hypokalemia