to investigate whether paneth-cell secretion is controlled via cholinergic mechanisms , the ultrastructure of paneth cells was studied in four animal groups : ( 1 ) germ-free ( gf ) control mice ( jcl : icr [ gn ] , male , 13 weeks old ) , ( 2 ) gf mice injected subcutaneously with atropine sulfate ( 200 mg/kg body weight , dissolved in physiological saline 20 mg/ml ) , ( 3 ) ex-gf mice inoculated with feces from specific-pathogen-free ( spf ) mice , and ( 4 ) ex-gf mice injected with atropine and inoculated with feces from spf mice .
C0596005
atropine sulfate
C0004259
atropine