in 13 cases in which the m components were measured over a period of time , three distinct patterns were observed , which may reflect the cellular and subcellular origin of the two proteins : 1 ) in 2 cases the minor component remained relatively stable while the dominant protein changed with time and treatment , suggesting the origin to be two cell lines -- the minor arising from a quiescent clone of the monoclonal gammopathy of undetermined significance , and the major m component arising from a more rapidly proliferating plasma cell line ;
C0026470
of
C0032112
plasma cell