an increase in initial chemotherapy intensity was evaluated in 29 patients with high risk metastatic non-seminomatous germ cell tumours ( nsgct ) of the testis , defined by the presence of multiple large lung metastases , liver , bone or brain metastases , or the combination of large abdominal mass with high serum concentration of the tumour markers alpha-foetoprotein ( afp ) or beta subunit of human chorionic gonadotrophin ( hcg ) ( afp greater than 500 ku/l or hcg greater than 1000 iu/l ) .
C0041365
tumour markers
C0106132
beta subunit