we can conclude , therefore , that the development of pp b cells into iga-producing plasma cells in gut-associated lymphoid tissues ( galt ) appears to require at least two steps : one which involves heavy chain switching to iga and which is governed by iga class-specific switch t cells in pp , and one which involves differentiation of post-switch b cells and which is governed by helper t cells in lymphoid tissues outside of pp ( such as mln and spleen ) .
C0039194
t cells
C0024296
lymphoid tissues