the low values of long-chain acyl-coa hydrolase ( ec 3.1.2.1 ) activity , as measured in intact mitochondria and on a mitochondrial matrix fraction ( i.e. , 1.6 nmol x min-1 per mg protein ) , do not support the proposal that the hydrolase activity plays a significant role in the loose-coupling of brown adipose tissue mitochondria , either by a futile cycle mechanism or promoted by free fatty acid-induced uncoupling .
C1510421
mitochondrial matrix
C0026237
mitochondria