these observations suggest that : ( 1 ) both estrogen and androgens control the viability of the granulosa cells and thereby the follicle , ( 2 ) the action of estrogen and androgen is mediated through receptors within the granulosa cells since these antihormones prevent the nuclear uptake of their respective hormone , ( 3 ) the granulosa cells of preovulatory follicles appears to be more dependent on estrogen than on androgen , and ( 4 ) each steroid appears to have a specific role in maintaining the granulosa cell ;
C0018120
follicle
C0018207
granulosa cell