clinical , haematological and instrumental ( doppler ultrasound ) parameters were assessed and no major events were noted in either of the two treatment groups though in the calcium heparin group , 2 patients showed clinical signs of dvt ( not confirmed by doppler ultrasound ) and no side effects were noticed , except for a cutaneous rash in one defibrotide patient and an episode of bleeding on the third postoperative day in a patient treated with calcium heparin .
C3540840
clinical signs
C0015230
cutaneous rash