1 ld 3098 ( cirazoline ) is an imidazoline derivative , possessing agonist properties at alpha-adrenoceptor sites.2 when transmitter release was measured directly as tritium overflow from perfused cat spleen preparations , prelabelled with [ ( 3 ) h ] -noradrenaline , ld 3098 was found to be 10 times more selective for presynaptic than for postsynaptic alpha-adrenoceptors.3 in addition , in this preparation , ld 3098 appears to induce a postsynaptic sensitization to the transmitter released by nerve depolarization because under conditions in which [ ( 3 ) h ] -noradrenaline overflow decreased , there was a paradoxical potentiation in the response to nerve stimulation .
C0034783
adrenoceptor
C0034784
alpha-adrenoceptors