in the proband a heritable chromosomal basis for his bilateral retinoblastomas is established [ 46 , xy , del ( 13 ) ( pter leads to q12.5 : : q22.1 leads to qter ) mat ] , and in his sister the relatively modest effects of triplication of the mid-portions of 13q are demonstrated [ 46 , xx , ins ( 12 ; 13 ) ( 12pter leads to 12p11.2 : :13q22.1 leads to 13q12.5 : :12p11.2 leads to 12qter ) mat ] .
C1520537
13q
C1520539
13q12