the effect of the increase in 5 alpha-reductase activity without a compensatory change in 3 alpha ( beta ) -hydroxysteroid dehydrogenase activity was to alter the mean ratio between 5 alpha-reductase and 3 alpha ( beta ) -hydroxysteriod dehydrogenase activities from 0.47 +/- 0.11 in the normal prostate to 1.84 +/- 0,19 in hyperplastic tissue .
C0039602
5 alpha-reductase
C0033572
prostate