during 60-day hypokinesia the hemopoietic system of rats developed important changes typical of the stress-state ( atrophy of thymico-lymphatic system , lymphopenia and neutrophilosis ) and hypokinesia per se ( activation at the early stage and inhibition at the late stage of bone marrow erythropiesis , reduction of the rate of lympho- and myelopoiesis by the end of the experiment , emergence of pathologically changed megakaryocytes ) .
C0005953
bone marrow
C0025166
megakaryocytes