dl-alpha-monofluoromethyldopa ( mfmd ) is a potent enzyme-activated irreversible inhibitor of aromatic l-amino acid decarboxylase which , when given to rats or mice at 100 and 250 mg/kg i.p. , respectively , causes a linear accumulation of l-dopa and 5htp and an exponential decline of noradrenaline , dopamine , and 5ht concentrations in the brain .
C0086045
concentrations
C0006104
brain