this rise was directly related to the degree of residual glucagon secretion and inversely related to plasma-free insulin concentrations.thus , we conclude : ( a ) that patients with iddm are , to varying degrees , dependent upon epinephrine-mediated beta-adrenergic mechanisms to promote glucose recovery from hypoglycemia and that the degree of this dependence upon epinephrine is an inverse function of the residual capacity to secrete glucagon in response to hypoglycemia in individual patients ;
C0017687
glucagon
C0020615
hypoglycemia