although both ageing of the brain da neurones and mptp ( as an example of a da-specific neurotoxin ) reproduce some aspects of the subregional striatal da loss found in idiopathic pd , neither of these two mechanisms mimicks the large caudate-putamen difference in da loss ( with the putamen much more affected than the caudate nucleus ) which is typical of idiopathic pd .
C0010097
striatal
C0007461
caudate nucleus