additional experiments employing deae-cellulose chromatography demonstrated that after incubation at 37 degrees c for 1 h , at least some in vivo activation of cytosolic [ 3h ] ru 38486-receptor complexes could be detected in cem-c7 cells , although the antagonist was less effective than the agonist in facilitating this conformational change .
C1383501
cytosolic
C0007634
cells