arthritis symptoms improved in 21 of these jra patients , and the improvement was significantly associated with a mean 1-hour serum mtx level of greater than or equal to 5.8 x 10 ( -7 ) m ( p = 0.008 ) and a dosage of greater than or equal to 0.3 mg/kg/week ( p = 0.004 ) .
C3495559
jra
C0025677
mtx