the selectivity of the effect of embolization on e ( 5- [ 14c ] ht ) , the lack of an effect on imipramine-insensitive e ( 5- [ 14c ] ht ) extraction , and the much smaller changes after progressive lobar ligation indicate that , although derecruitment of vascular surface area secondary to mechanical obstruction may contribute to postembolization depression of e ( 5- [ 14c ] ht ) , additional mechanisms such as local saturation of 5-ht uptake or selective damage to endothelial cell transport of 5-ht may underlie these observations .
C0023690
ligation
C0005847
vascular