as it has been shown that various kinds of immunopotentiators inhibit the hepatic microsomal drug-metabolizing enzymes and reduce the activation of masked compounds such as tegafur , we investigated the influence of immunopotentiators ( ok-432 and psk ) on the activation of carmofur ( hcfu ) , which is known to be transformed spontaneously in to the tumor-active substance , 5-fluorouracil ( 5-fu ) , in vivo , and compared the results to those obtained for tegafur .
C0016360
5-fu
C0016778
tegafur