before commencing the randomized thrombolysis in myocardial infarction phase ii ( timi ii ) study , 370 patients were administered intravenous recombinant tissue plasminogen activator ( rt-pa ) within 4 hours of onset of acute myocardial infarction ( ami ) and assigned to 2-hour ( immediate ) percutaneous transluminal angioplasty ( n = 33 ) , 18- to 48-hour ( delayed ) angioplasty ( n = 288 ) or no angioplasty ( n = 49 ) in a nonrandomized , observational pilot study .
C0032143
recombinant tissue
C0027051
myocardial