as csa is known to block the signalling cascade initiated by perturbation of t-cell receptor ( tcr ) , it is suggested that both the ia expression in the thymus and the signalling via receptors on thymocytes , the signals presumably generated by tcr binding to class ii mhc molecules , might be necessary for phenotypic differentiation of class ii mhc-restricted t cells ( cd4+8- cells ) , but not for class i mhc-restricted t cells ( cd4-8+ ) .
C0034790
t-cell receptor
C0039194
t cells