treatment with the cysteine cathepsin inhibitor l-trans-epoxysuccinylleucylamido ( 4-guanido ) butane ( e64 ) conferred resistance to c12-im , showing that , in these cells , as previously demonstrated for chinese hamster ovary fibroblasts , cysteine proteases were major cytotoxic agents involved in killing by c12-im .
C0007634
cells
C0016030
fibroblasts