by a strict , permanently normotensive decrease of blood pressure -- as pharmacotherapy above all the beta-receptor blocker propranolol alone or in the approved combination therapy with dihydralazine and/or hydrochlorothiazide was used -- in connection with suitable measures for the intervention of other individual factors with effect on heart and circulation the risk of complications in definitive hypertension could be reduced .
C0020261
hydrochlorothiazide
C0020538
hypertension