this new protein ( cam-bp103/97 ) has now been identified as a major substrate for protein kinase c in erythrocytes since phosphorylation of both of its subunits ( mr = 103,000 and 97,000 ) is elevated 3-15-fold in the presence of the phorbol ester , 12-o-tetradecanoylphorbol beta-acetate ( tpa ) , under the following conditions : ghost membranes incubated with protein kinase c purified from rat brain , ghost membranes from erythrocytes pretreated with tpa , and intact erythrocytes metabolically labeled with 32po4 and stimulated by tpa .
C0031586
phorbol ester
C0039654
tpa