to obtain a dynamic and non-invasive picture of hepatic fibrosis in pre-cirrhotic liver diseases we measured both the concentration of the n-terminal peptide of procollagen iii , as a marker of collagen synthesis , and the activity of pz-peptidase , an enzyme involved in collagen degradation , in the serum of alcoholic or chronic viral hepatitis patients .
C0023884
liver
C0276623
chronic viral hepatitis