we have investigated this here by fractionating mouse bone marrow and isolating haematopoietic stem cells using a three-step method combining equilibrium density centrifugation and two fluorescence-activated cell sortings ( facs ) , and have tested the ability of each bone marrow fraction , including highly purified haematopoietic stem cells , to generate osteoclasts during co-culture with preosteoclast-free embryonic long bones .
C0007634
cell
C0018956
haematopoietic stem cells