the effect on the heparin thrombin clotting time ( htct ) of a so-called acute phase protein , alpha1-acid glycoprotein , was studied in test systems consisting of purified fibrinogen , antithrombin iii , heparin and thrombin , and compared to the effect of platelet material ( crude platelet factor 4 ) .
C0001347
acute
C0016006
fibrinogen