the localization of three antigenic domains ( composed of 16 distinct epitopes ) within the primary structure was performed by ( i ) amino-terminal sequencing of three immunoreactive fragments of protein e and ( ii ) sequencing the protein e-coding regions of seven antigenic variants of tick-borne encephalitis virus that had been selected in the presence of neutralizing monoclonal antibodies directed against the e protein .
C0003320
antigenic
C0003316
epitopes