when investigating the effects of divalent cations ( mg2+ , ca2+ , sr2+ , ba2+ , mn2+ and ni2+ ) on 3h-baclofen binding to rat cerebellar synaptic membranes , we found that the specific binding of 3h-baclofen was not only dependent on divalent cations , but was increased dose-dependently in the presence of these cations .
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divalent
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cations