research on antimetabolites of nucleic acid purines led to drugs for the treatment of acute leukemia ( 6-mercaptopurine and thioguanine ) , gout and hyperuricemia ( allopurinol ) , and herpesvirus infections ( acyclovir ) , and for the prevention of organ transplant rejection ( azathioprine ) .
C0018099
gout
C0002144
allopurinol