the following lines of experimentation in the present study suggest that metabolic cooperativity exists between granulosa cells and their enclosed oocytes , i.e. , gap junctions are functional , and that in most cases examined , greater than 85 % of the metabolites present in follicle-enclosed oocytes were originally taken up by the granulosa cells and transferred to the oocyte via gap junctions : ( 1 ) when incubated with various radiolabeled compounds , follicle-enclosed oocytes contained more intracellular radioactivity than did oocytes with no attached granulosa cells ( denuded oocytes ) ;
C0018120
follicle
C0018207
granulosa cells