during prophylaxis , infections per patient year were comparable in the groups receiving trimethoprim ( 0.0 ) , nitrofurantoin ( 0.14 ) , or trimethoprim-sulfamethoxazole ( 0.15 ) and occurred less frequently than in patients receiving placebo ( 2.8 ; p less than 0.001 , placebo versus each drug regimen ) .
C0041041
trimethoprim
C0041044
trimethoprim-sulfamethoxazole