evidence for premature initiation of deoxyribonucleic acid ( dna ) replication after thymine starvation of bacillus subtilis w23t ( - ) is presented , based on ( i ) increase in the number of ade ( + ) relative to met ( + ) transformants yielded by the dna isolated from cultures after starvation ( the ade ( - ) marker being near the origin of replication , whereas met ( - ) is close to the terminus ) , and ( ii ) increase in both the initial rate and final level of tritiated thymine incorporation in the presence of chloramphenicol after release from starvation .
C0598312
deoxyribonucleic acid
C0012854
dna