since the apical tight junctions of the epithelium never appeared open or never contained hrp in the spaces between the fusion points , and since the intercellular spaces between adjacent epithelial cells below the junctions only infrequently contained tracer after 5 min , by increasing amounts after 15-60 min of hrp perfusion , a vesicular transport of hrp from the apical epithelial surface to the intercellular spaces , bypassing the tight junctions , is suggested .
C0007634
the
C0242358
tight junctions