the rate of iodination and the extent and the efficiency of coupling , assessed by the t4 residues formed per atom of iodine bound , have been studied by in vitro enzymatic iodination of iodine-poor ( 0.01 % i ) human goiter thyroglobulin ( tgb ; 1 microm ) with varying concentrations of iodide ( 0.75 x 10 ( -5 ) -10 ( -4 ) m i- ) , lactoperoxidase ( 0.1-5 micrograms/ml ) , and hydrogen peroxide ( h2o2 ) generated from glucose ( 1 mg/ml ) and glucose oxidase ( 0.025-2.5 mu/ml ) .
C0018021
goiter
C0040123
thyroglobulin