these results 1 ) have demonstrated the ability of a peptidic grf antagonist to specifically suppress pulsatile gh release after its systemic administration , presumably by acting on pituitary grf receptors , and 2 ) support the notion that grf receptors are also present in the hypothalamus and are available for the physiological mediation of grf-induced inhibition of gh release by a central mechanism .
C0020663
hypothalamus
C0037668
grf