in one patient , microscopic examination of biopsy specimens of two lesions that were taken within 24 and 72 hours , respectively , after they had turned black demonstrated the following histologic findings : blood clots and hemorrhage in the stratum corneum , degeneration and necrosis of epidermal cells , eosinophilic cytoplasmic masses within degenerating epidermal cells , thrombosis of superficial and deeper dermal blood vessels , a mononuclear cell infiltrate in and around dermal blood vessels , and a mixed polymorphonuclear and lymphocytic infiltration in the areas of hemorrhage and degenerating epidermis .
C3496194
epidermal cells
C0014520
epidermis