in contrast , maturation of the capacity of the splenic b-cell population to reconstitute irradiated recipients to give a heterogeneous , adult-like pfc response to three 'thymic-independent ' antigens ( tnp-pa , dnp-ficoll and tnp-ba ) takes place considerably later ( between 3 and 4 weeks of age ) .
C1511002
maturation
C0007634
pfc