the mean plasma t1/2 of cimetidine was 3.1 h in mild renal dysfunction ( creatinine clearance 50-75 ml/min ) and 4.5 h in severe renal failure ( creatinine clearance 5-15 ml/min ) and of cimetidine sulphoxide 5.3 and 14.4 h respectively .
C0022646
renal
C0035078
renal failure