the factors contributing to increase of the uric acid in csf were thought to be increased permeability of blood-csf barrier , global damage of brain tissue , increased nucleic acid catabolism in the central nervous system ( cns ) for example in tumor , inflammation or immunoreaction , increased of xanthine , hypoxanthine or xanthine oxidase activity in the cns , directly increased of plasma components into the csf due to such as subarachnoid hemorrhage , intraventricular hemorrhage , bleeding in the tumor or surgical operation , dysfunction of the csf dynamics .
C0038525
subarachnoid
C0019080
bleeding