( +/- ) -isoprenaline was inactive and failed to inhibit the effect of adrenaline.3 the effect of adrenaline on kininogen could be reproduced in vitro by incubation of whole blood , but not cell-free plasma , with the catecholamine for 5 min at 37 degrees c.4 propranolol or phenoxybenzamine , as well as heparin or acetylsalicylic acid ( aspirin ) , blocked the reduction of rat blood kininogen by adrenaline in vivo and in vitro .
C0022245
isoprenaline
C0007412
catecholamine