the effects of three single oral doses ( 25 mg , 50 mg and 100 mg ) of amitriptyline and desipramine , and of placebo , were compared on a range of cholinergic functions ( resting pupil diameter , pilocarpine-evoked miosis , baseline-sweating , carbachol-evoked sweating , salivation , heart rate ) in eight healthy volunteers .
C0026205
miosis
C0006945
carbachol