the effects of heat inactivation , decomplemented rat serum , egta treatment , removal of any possible anti-myelin antibody by absorption using syngeneic myelin and absence of surface staining for immunoglobulins on serum-treated oligodendrocytes , c9 depletion and reconstitution , and oligodendrocyte staining for surface c9 demonstrate that this cytotoxicity is mediated by complement via antibody independent activation of the classical pathway and is membrane attack complex dependent .
C0229671
serum
C0009498
complement