choriocarcinomata and cases where histology has not been carried out but which have poor prognosis ( extra-pulmonary metastases , numerous or large pulmonary metastases , long delay in treatment and the excretion of high levels of hcg ) justify chemotherapy in which vincristine is followed by methotrexate or vincristine is followed by actinomycine d .
C0008497
choriocarcinomata
C0025677
methotrexate