to shed further light on the mechanism of age-associated t-cell-mediated immunoregulatory alterations in gut non-specific mucosal immune responses , we studied in vitro the function of a variety of concanavalin a ( con a ) -activated immunoregulatory t-cell subsets derived from aged murine peyer 's patches ( pp ) ( balb/c > 24 months old ) in the production of class-specific immunoglobulins ( ig ) by young ( 5-8 months old ) lipopolysaccharide ( lps ) -activated pp b cells .
C0026724
mucosal
C0031272
pp