the results of the simulation for a single cycle initiated in fully recovered tissue under normal and simplified pathological conditions ( ischemia and infaraction ) indicate ( a ) that the conduction velocity of the cellular action potential in ventricular cardiac tissue may be several ( 3-5 ) times greater than is normally considered to be the case , ( b ) that the ventricular activation wave front propagates transmurally from endocardium to epicardium despite fiber orientation parallel to these surfaces , without the need for assuming the existence of either lateral contacts between adjacent cells or fibers with a transmural orientation , ( c ) the wave front of activation propagates through ventricular cardiac tissue with an anisotropic phase velocity , ( d ) the presence of ischemia and infarction gives rise to tangential spread of activation , and ( e ) small subendocardial infarcts should not be considered to be electrically silent .
C0022116
ischemia
C0021308
infarcts