the gonadotrope cells of the ovine anterior pituitary were insulated from hypothalamic inputs by imposing an immunologic barrier generated by active immunization of ovariectomized ewes against gonadotropin-releasing hormone ( gnrh ) conjugated to keyhole limpet hemocyanin ( klh ) through a p-aminophenylacetic acid bridge .
C0020663
hypothalamic
C0023610
gnrh