the km values for isoprenaline for the sulphotransferase of mouse liver and monkey lung , are respectively , 51,3 microm and 138 microm . the significance of this detoxication reaction is discussed in relation to ( a ) the importance of lung as a potential biotransformation site of isoprenaline , ( b ) asthma deaths supposed to be associated with the use of isoprenaline in the form of pressurised aerosols and ( c ) the ability of the different tissues to synthesize paps in vitro .
C0024109
lung
C0004096
asthma