fk506 , a neutral macrolide with immunosuppressive properties , was shown to selectively and rapidly inhibit the accumulation of il-2 mrna , as well as the mrnas of other early ( e ) phase t cell activation genes such as il-3 , il-4 , gm-csf , tnf alpha , ifn-gamma , and c-myc in activated human peripheral blood t cells .
C1155065
t cell activation
C0039194
t