combinations of piperacillin ( pip ) with 3 systemic fluoroquinolones : pefloxacin ( pef ) , ofloxacin ( ofl ) and ciprofloxacin ( cip ) were evaluated by checkerboard technique ( bacteriostatic activity ) and by time-killing curve technique ( bactericidal activity as a function of time ) for 4 bacterial strains with following mics ( micrograms/ml ) : 1 e. coli ( pip : 1 , pef : 0.12 , ofl : 0.06 , cip : 0.016 ) ;
C0949665
fluoroquinolones
C0030771
pef