histopathologic studies at 3 hours , 6 hours , 24 hours , 14 days , and 4 weeks after bcg showed a definite sequence of events occurred , progressing from 1 ) inflammatory cell response at the periphery of the lesion , disruption of melanogenesis , extensive dumping of pigment from melanoma cells , proceeding to actual cell death at 24 hours , to 2 ) macrophages containing melanin and granulomas replacing tumor by 2 weeks .
C0007634
cell
C0007587
cell death