a three-compartment explanatory model was used to derive fractional rate constants for the forward flux of l-dopa into the endothelium of the brain capillaries from the blood ( 1.54 +/- 0.37 min-1 ) , the back flux of dopa and/or its metabolites to the blood from the endothelium ( 0.67 +/- 0.05 min-1 ) , the formation of dopamine from dopa ( 0.20 +/- 0.04 min-1 ) , and the destruction of dopamine ( 0.04 +/- 0.02 min-1 ) .
C0023570
l-dopa
C0013023
dopa