the transition from replication-dependent to replication-independent histone synthesis during gametogenesis is a regular process directed to the formation of a highly compacted metabolically inert chromatin ( males ) and to the formation of histone protein pool in order to provide the chromatin nucleosome structure in the sperm nucleus during fertilization , as well as the nuclear chromatin in zygotes and blastomeres ( females ) .
C0008546
chromatin
C0028623
nucleosome