we conclude that lys-107 , lys-125 , and lys-136 are situated within the heparin-binding site of human antithrombin and that binding of heparin to antithrombin causes a conformational change of antithrombin that leads to the exposure of lys-236 for s-dabitc modification .
C0724532
human antithrombin
C0003438
antithrombin