microinjection ( icv ) of human recombinant il-1 beta ( 50 ng ) caused acute ( response within 60 min ) increases in colonic temperature ( 1.8 degrees c ) , oxygen consumption ( vo2 ; 36 % ) , white blood cell count ( 96 % ) , and brown adipose tissue ( bat ) activity ( mitochondrial gdp binding , 129 % ) in conscious rats .
C0086418
human
C0021753
recombinant il-1 beta