for the transferrin receptor this results from a net internalization of receptor molecules from the plasma membrane pool , while for the asgp receptor this decrease is accounted for by a 3.5-fold reduction in ligand binding affinity ( 6.6 x 10 ( -8 ) m to 24.0 x 10 ( -8 ) m ) , with essentially no change in the number of asgp receptors recoverable from the plasma membrane pool by immunoprecipitation .
C0034845
transferrin receptor
C1517880
ligand binding