in this study , the possible relationship between cell shape , microtubules , and granulosa cell steroidogenesis in vitro was further explored by culturing ( 24 h ) granulosa cells obtained from antral follicles of pregnant mare 's serum gonadotropin-treated rats in either eagles 's minimum essential medium alone ( mem-cells ) or in collagen gels ( gel-cells ) in the absence or presence of colchicine , a microtubule-depolymerizing agent previously shown to inhibit cell-spreading in vitro .
C0026046
microtubule
C0007634
cell