because of the demonstrated relationship between n6-dimethylation of adenine in 23s rrna and clinical resistance to macrolide , lincosamide , and streptogramin b-type antibiotics in staphylococci and streptococci , the observed systematic differences found in rrna methylation combined with greater cellular permeability may be related to the relatively greater efficacy of macrolide , lincosamide , and streptogramin b-type antibiotics in treating infections caused by gram-positive organisms .
C0035704
23s rrna
C0035701
rrna