members of the genera rickettsia , coxiella and rochalimaea show considerable diversity in host cell range ( in vivo vs. in vitro ) , kind of association with host cell ( pericellular , intracellular ) , mode of entry , interactions with various host cell membranes , intracellular localization ( intraphagosomal , free in cytoplasm , intranuclear ) , adaptation to preferred microhabitat ( e.g. , optimal ph for enzymes ) , details of growth cycle , mechanisms of host cell damage .
C0007634
cell
C0010834
cytoplasm