in conclusion , absolute proximal reabsorption of bicarbonate , chloride , and water during carbonic anhydrase inhibition 1 ) proceeds isohydrically , with minimal anion concentration gradients generated , over a wide range of filtered loads , and 2 ) can be flow dependent ( with plasma loading ) as well as modulated by peritubular protein concentration , even though passive chloride transport is minimized .
C0003075
anion
C0008203
chloride