a series of hla-dr-reactive mouse anti-human b cell or anti-ia monoclonal antibodies ( mab ) have been used to explore the serological complexity of human class ii antigens at the determinant level , using two techniques : ( a ) cross antibody-binding competitor assays using 125i-labeled and-unlabeled mab were performed to study the topological organization of the corresponding determinants to determine epitopic clusters recognized by this collection of mab and ( b ) differential reactivity of mab to detergent-solobilized solid-phase-immobilized hla-dr molecules to determine epitopes expressed on identical dr isotypes .
C0086418
human
C0019764
hla-dr