using radioactive steroid substrates of both c21 and c19 configurations , kinetic studies of these tissues showed that the major pathway of testosterone production was via the delta5 pathway , i.e . pregnenolone leads to 17 alpha-hydroxypregnenolone leads to dehydroepiandrosterone leads to androstenedione and androstenediol leads to testosterone , with the accumulation of dehydroepiandrosterone and androstenediol .
C0373704
pregnenolone
C0376260
17 alpha-hydroxypregnenolone