when multicellular spheroids , which simulate small bits of tissue , are exposed to a freeze-thaw ( ft ) cycle , the survival of the individual cells in the spheroid is higher if the cells of the spheroid are trypsinized and plated as single cells immediately after thawing than if the spheroid is allowed to remain intact for 4 hr and then trypsinized for plating .
C0007620
survival
C0007634
the cells