the results provide evidence for a hitherto unsuspected messenger role for sodium ions in excitable tissue , whereby neuronal activity and the resultant influx of sodium will cause activation of phospholipase systems involved in hydrolysis of phosphatidylinositols , thereby generating two second messengers , the inositol phosphates , which mobilize calcium from internal stores , and the diacylglycerols , which activate protein kinase c .
C0031671
phospholipase
C0020291
hydrolysis