the presence of 4 human malignant tumors ( 1 breast , 1 lung , and 2 colon carcinomas ) growing subcutaneously as heterotransplants in nude mice did not significantly affect the body weights of adult animals until the tumors reached very large dimensions ( tumor wt greater than 15 % of the body wt ) .
C0006826
malignant tumors
C0027651
tumor