whereas vessel ingrowth in corneas containing tumor cell-conditioned media was detected as early as day 2 or 3 and was maximal by day 7 , inclusion of mitoxantrone or bisantrene in the conditioned media at a 1:1 ratio ( 160 microm mitoxantrone or 32 microm bisantrene ) resulted in complete inhibition of angiogenesis throughout the 14-day evaluation period .
C0005847
vessel
C1510884
inhibition of angiogenesis