in order to determine the possible effects of the circulating intrinsic factor antibodies ( ifa ) on gastric morphology and secretory function , four groups of 12 rats each received intravenous injection daily for 8 to 12 weeks of immunoglobulin g ( igg ) fractions separated on deae-cellulose columns from various sources : ( 1 ) sera of patients with pernicious anemia , containing both ifa and parietal cell antibodies ( pca ) , ( 2 ) sera from patients with atrophic gastritis , containing parietal cell antibody only , and ( 3 ) and ( 4 ) sera of rabbits immunized with semipurified human or rat intrinsic factor ( if ) .
C0038351
gastric
C0017154
atrophic