medium conditioned by brl-3a cells , a known source of insulin-like growth factor ii ( igf-ii ) , induced phenotypic transformation ( anchorage-independent proliferation ) of mouse balb/c 3t3 fibroblasts but not rat nrk-49f fibroblasts , in the presence of 10 % calf serum .
C0007634
cells
C0016030
fibroblasts