this reduced stroke volume occurred despite a 40 % increase in myocardial contractility ( peak lv dp/dt ) and elevation of left ventricular end diastolic pressure . beta-adrenoceptor blockade with propranolol abolished the rise in peak lv dp/dt , while vagal blockade with methylscopolamine abolished the bradycardia and combined blockade with propranolol and methylscopolamine abolished the rise in peak lv dp/dt and reduced the bradycardia .
C0033497
propranolol
C0428977
bradycardia