in conclusion : ( 1 ) plasma plp regulation in patients with liver disease is abnormal , ( 2 ) a significant factor in the decrease in plasma plp after intravenous pyridoxine administration in these patients appears to be an increase in the total plasma clearance of the coenzyme , and ( 3 ) it is postulated that this may be due to increased degradation of plp by the diseased liver .
C0023895
liver disease
C0023884
liver