differentiation of cll cells , induced by culturing the cells with 12-0-tetradecanoyl phorbol-13-acetate ( tpa ) , was accompanied by increases in mhc class ii expression at the cell surface of up to more than 20-fold , and resulted in detectable expression of dq antigens on greater than 90 % of the cells in all the subjects studied .
C0007589
differentiation
C0007634
cells