analysis of the idiotypes associated with the monoclonal antibodies showed those that combined with cyclic sp1 also inhibited the binding of a common human anti-hbs ( chbs ) idiotype with its rabbit anti-idiotype serum , whereas a monoclonal antibody that did not react with the cyclic sp1 epitope failed to inhibit the chbs idiotype-anti-idiotype reaction .
C0003316
epitope
C0021013
idiotype