the chinese subjects had at least a twofold greater sensitivity to the beta-blocking effects of propranolol than the white subjects , as indicated by the mean ( +/- sem ) plasma concentrations producing a 20 percent reduction in the heart rate in both the supine position ( 197 +/- 31 vs. 536 +/- 58 nmol per liter ; p less than 0.05 ) and the upright position ( 131 +/- 27 vs. 343 +/- 39 nmol per liter ; p less than 0.05 ) and after exercise testing ( 96 +/- 12 vs. 185 +/- 23 nmol per liter ; p less than 0.05 ) .
C0033497
propranolol
C0428977
reduction