1 we have investigated the effects of sulphasalazine and of its principal colonic metabolites ( 5-aminosalicylic acid and sulphapyridine ) on prostaglandin inactivation , synthesis and actions on gastrointestinal smooth muscle.2 sulphasalazine inhibits prostaglandin f ( 2alpha ) breakdown in 100,000 g supernatants in all organs so far tested from 7 species with an id ( 50 ) of approx .
C0033554
prostaglandin
C0033561
prostaglandin f