between april 1981 and may 1984 , 61 patients with advanced diffuse large-cell lymphoma completed treatment with macop-b ( methotrexate with leucovorin rescue , doxorubicin , cyclophosphamide , vincristine , prednisone , and bleomycin ) , an innovative pilot chemotherapy program emphasizing weekly treatment , antibiotic prophylaxis , daily corticosteroid treatments , and brief duration ( 12 weeks ) .
C0279852
macop-b
C0010583
cyclophosphamide