in all hearts , treated and untreated , the development of severe cell damage , whenever it occurs , is closely associated with cell swelling , mitochondrial dilation with concomitant appearance of amorphous osmiophilic densities , and abnormalities in and , ultimately disappearance of lysosomes , suggesting that damage to cell membranes is a central event in the progression of reversible injury to irreversible infarction and that protection of membrane integrity should be a reasonable aim in efforts to ameliorate or delay ischemic injury .
C0007634
cell
C0026237
mitochondrial