in a prospective randomised trial in which 93 patients undergoing elective colorectal operations were given a short prophylactic course of metronidazole and kanamycin orally or systemically , postoperative sepsis occurred in only 3 ( 6.5 % ) of those given antimicrobials systemically , compared with 17 ( 36 % ) of those given oral prophylaxis ( p less than 0.01 ) .
C0025872
metronidazole
C1136254
antimicrobials