seventy-one patients receiving a minimum of two courses of high-dose intracavitary cisplatin ( 100-200 mg/m2/course ) with i.v . thiosulfate administered to protect against cisplatin-induced renal insufficiency were retrospectively evaluated to examine the influence of thiosulfate and large cumulative doses of cisplatin on the incidence of hypomagnesemia .
C0008838
cisplatin
C0035078
renal insufficiency