human alpha-thrombin , the procoagulant activation product of prothrombin , elicits chemotaxis in human peripheral blood monocytes and several macrophagelike continuous cell lines , most notably j-774.2 , but not in human peripheral blood granulocytes . alpha-thrombin is effective in stimulating cell movement at concentrations ranging from 10 ( -10 ) to 10 ( -6 ) m but is optimally active at 10 ( -8 ) m .
C0026473
peripheral blood monocytes
C0229664
peripheral blood