consistent with an increase in platelet-vascular interactions in vivo , excretion of a prostacyclin metabolite was also significantly increased ( p less than 0.005 ) in the patients with systemic sclerosis ( 248 ( 39 ) v 112 ( 10 ) ng/g creatinine ) and tended to increase further on cooling .
C0033567
prostacyclin
C0036421
systemic sclerosis