it is shown here that eight alloreactive cd4+ t cell clones ( tcc ) secreted significant amounts of tnf-alpha after stimulation with either specific alloantigen or 12-o-tetradecanoylphorbol 13-acetate together with the calcium ionophore ionomycin ( up to 50 ng/ml/24 h/10 ( 6 ) cells ) whereas cd8+ tcc failed to do so ( max . 2 ng/ml/24 h/10 ( 6 ) cells ) .
C1327616
secreted
C0007634
cells