the effect of ang-ii on granulosa cell ang-ii receptor content was mimicked by the ca2+ ionophore a23187 , but not by the phorbol ester 12-o-tetradecanoylphorbol 13-acetate , suggesting that an elevation of cytosolic ca2+ may be important for the homologous down-regulation of the ang-ii receptor .
C0031586
phorbol ester
C0039654
12-o-tetradecanoylphorbol 13-acetate