after oral treatment of the dams during the period of organogenesis ( days 6-15 of gestation ) with both phb and dph in doses causing marked symptoms and signs of toxicity ( 40 and 170 mg/kg/day respectively ) , an abnormally high incidence of cleft palate was observed in the foetuses ( 4.3 % and 9.3 % resp . ) .
C0032961
gestation
C0031412
phb