since lamellar ichthyosis and psoriasis share similar features of epidermal hyperproliferation and the presence of activated , dilated , tortuous vessels , but differ in the lack of immunologic cellular activity , their contrasting response to cyclosporine suggests that the target of the action of cyclosporine is the immune system rather than the keratinocyte or the endothelium .
C0033860
psoriasis
C0010592
cyclosporine