the reaction of the holo- ( beta-plp ) 2 with alpha subunits at 25 degrees c is accompanied by a negative enthalpy change , which is almost twice as large as that for complex formation with the apo-beta 2 protein , thus indicating that the interaction enthalpy becomes more favorable in the presence of the coenzyme pyridoxal 5'-phosphate ( plp ) .
C0009235
coenzyme
C0034266
pyridoxal 5