in a blind cross-over study , 12 patients with ventricular arrhythmias ( vpc 's ; lown grades ii-ivb ) resistant to a daily dose of quinidine 1.2 g , disopyramide 0.8 g , n-propyl-ajmaline 0.1 g were randomly given , each dose for one week , placebo ( pl ) , mexiletine ( mex ; 400 , 600 , 800 mg daily ) and lorcainide ( lor ; 200 , 300 , 400 mg daily ) .
C0151636
vpc 's
C0025887
mexiletine