in the human leukemia k-562 ( s6 ) cell line ( a ) the accumulation of alpha-globin chains is low or absent , ( b ) zeta-globin gene expression is correlated with expression of epsilon-chains and ( c ) the genes responsible for the terminal cell division are not operated within 8-12 cell cycles , while k-562 ( s6 ) cells are fully induced to erythroid differentiation .
C0002270
alpha-globin
C0043472
zeta-globin