a 3.7-kilobase ( kb ) genomic clone of the human beta-globin gene , including 1.5-kb upstream and approximately 0.5-kb downstream , was utilized in chromosomal in situ hybridization for precise mapping of the beta-globin locus on peripheral blood lymphocyte-derived metaphases from a normal male , and for further evaluation of a clonal t ( 7 ; 11 ) ( q22 ; p15 ) translocation on bone marrow-derived metaphases from a 46-year-old male with erythroleukemia .
C0008633
chromosomal
C1708726
locus