comparison of the formation of radiation-induced dna -- protein crosslinks in whole chromatin with that in the dna -- core histone complex has demonstrated that the core histones are the specific proteins involved in crosslinking . gamma irradiation of the chromatin subunit in the presence of radical scavengers has shown the hydroxyl radical to be the most effective aqueous radical intermediate for the promotion of crosslinking and the solvated electron and superoxide radical to be essentially ineffective .
C0598312
formation
C0012854
dna