unlike the changes observed in the polyamine levels after pma treatment , the activities of ornithine and s-adenosylmethionine decarboxylases , which are polyamine biosynthetic enzymes , did not significantly change . alpha-methylornithine and alpha-difluoromethylornithine and methylglyoxal bis ( guanylhydrazone ) , which are inhibitors of the polyamine biosynthetic enzymes , did not affect differentiation in control or pma-treated cells .
C0029277
ornithine
C0002260
alpha-difluoromethylornithine