in the present report , we stimulated murine peyer 's patch ( pp ) b cells by nonspecific multifunctional b cell stimulatory factors ( bsf ) secreted by one of several autoreactive ( self-major histocompatibility complex ( mhc ) -class ii antigen-responsive ) t cell hybridoma clones derived from pp of syngeneic mature adult mice , and then determined in vitro whether aging-associated intrinsic defects could be demonstrated in the proliferation of , and the synthesis and secretion of mucosal iga by , the bsf-activated b cells .
C1327616
secreted
C0007634
bsf