the mutation ( tdci ) responsible for the altered expression of the dehydratase in mb201 was located at min 91 on the e. coli chromosome and appeared to tightly linked to if not identical with pgi , the gene encoding phosphoglucose isomerase , as judged by growth experiments on glucose and fructose , direct assay of phosphoglucose isomerase activity , spontaneous and simultaneous reversion of mb201 ( tdci ) to tdci+ and pgi+ phenotype , and cosegregation of the two loci during transduction with p1 phage .
C0008633
chromosome
C1708726
loci