this inhibition does not appear to involve a direct physical interaction of pge2 with the avp receptor which is coupled to adenylate cyclase , since ccct cells must be preincubated with pge2 for 20 min for the inhibition to be observed , and since pge2 added to the apical surface of ccct cells inhibits camp release in response to avp acting from the basolateral surface .
C0007634
cells
C0699040
surface of