renal beta-adrenoceptors activate adenylate cyclase in glomeruli and distal nephrons via an interaction with the stimulatory g protein gs . alpha 1-adrenoceptors bind to an as yet uncharacterized g protein and activate phospholipase c to produce the putative second messengers 1,4,5-inositol trisphosphate and diacylglycerol . alpha 1-adrenoceptors are found in most segments of the nephron where they regulate sodium reabsorption , and metabolic functions such as gluconeogenesis .
C0022646
renal
C0027713
nephron