to determine the effect of benzodiazepine premedication on central nervous system and cardiovascular effects of bupivacaine , the authors administered toxic doses of bupivacaine to awake spontaneously breathing pigs after intravenous premedication with midazolam ( 0.06 mg/kg ) , diazepam ( 0.15 mg/kg ) , or saline .
C0005064
benzodiazepine
C0026056
midazolam