glyburide ( 10 ( -7 ) to 3 x 10 ( -5 ) m ) , a sulfonylurea which has been shown to block the atp-modulated potassium channel in insulin-secreting cells , caused concentration-dependent shifts to the right ( up to 100-fold ) of the ic50 value for brl 34915 and diazoxide , and at 10 ( -6 ) m , abolished the relaxation response to minoxidil sulfate .
C0017628
glyburide
C0038766
sulfonylurea