the effects of simvastatin ( mk-733 ) , a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase , on serum lipids , lipoproteins , and apolipoproteins were investigated in 29 patients ( 12 men , 17 women , aged 37 to 73 ) with moderate to severe hypercholesterolemia .
C0074554
simvastatin
C0020443
hypercholesterolemia