the results support the idea ( i ) that a bacterial or host-derived collagenase is not required for extensive corneal damage during a p. aeruginosa corneal infection , and ( ii ) that a p. aeruginosa corneal infection may severly damage the cornea by producing extensive corneal edema and by causing the loss of the corneal proteoglycan ground substance , thus resulting in dispersal of undamaged collagen fibrils , weakening of the cornea , and subsequent descemetocele formation and corneal perforation by the anterior chamber pressure .
C0339289
corneal damage
C0339293
corneal perforation