the acute administration of an anticonvulsant dose of ethosuximide ( 150 mg/kg ) had no effect on brain gamma-aminobutyric acid ( gaba ) concentration , whereas a toxic dose ( 400 mg/kg ) increased significantly the concentration of brain gaba ( 1.23 +/- 0.05 vs. 1.92 +/- 0.14 mumol/g of wet tissue ) .
C0086045
concentration
C0006104
brain