the possible role of protein kinase-c ( pkc ) , calcium and cyclic amp ( camp ) in mediating the metabolic and mitogenic effects of insulin-like growth factor-i ( igf-i ) on chondrocytes was investigated using a pkc activator ( phorbol ester 12,13-dibutyrate , pdbu ) , a pkc inhibitor ( compound h7 ) , a calcium channel blocker , ( verapamil ) and a camp analogue ( dibutyryl camp ) .
C0001455
camp
C0012054
dibutyryl camp