mean ( +/- standard deviation ) values for maximal concentration of tritiated imipramine binding sites on platelet membranes were significantly lower in patients with bipolar and familial pure depressive disease ( 754 +/- 149 and 870 +/- 241 femtomoles [ fmole ] /mg of protein , respectively ) than in patients with depressive spectrum and sporadic depressive disease ( 1,236 +/- 241 and 1,188 +/- 325 fmole/mg of protein , respectively ) , neither of which differed from healthy controls ( 1,238 +/- 201 fmole/mg of protein ) .
C0020934
imipramine
C0011581
depressive