this method has allowed the demonstration of coordinate regulation between the gene coding for phosphoribosylglycineamide synthetase [ 5-phosphoribosylamine : glycine ligase ( adp-forming ) , ec 6.3.4.13 ] , defective in our ade-c mutants , and the gene coding for phoshoribosylaminoimidazole synthetase [ 5'-phosphoribosylformylglycinamidine cyclo-ligase ( adp-forming ) , ec 6.3.3.1 ] , defective in our ade-g mutants .
C0023689
ligase
C1334397
gene