as an initial approach to experiments directed toward effective adoptive immunotherapy for cancer using lymphokine genes , we transferred retrovirally a complementary dna encoding mouse gamma-interferon ( ifn-gamma ) into a specific cytotoxic t-lymphocyte clone , designated e-4 , against 203 glioma cells ( a 20-methylcholanthrene-induced mouse glioma line ) and confirmed the efficacy of ifn-gamma production from the exogenous gene on augmentation of tumor targeting .
C0006826
cancer
C0027651
tumor