in pt , several abnormalities of mk colony formation were observed : 1 ) increased circulating cfu-mk numbers , 2 ) increased mix-mk colony formation , 3 ) spontaneous mk colony formation without phytohemagglutinin-stimulated leukocyte-conditioned medium and normal serum , 4 ) decreased proportion of larger mk colonies ( greater than 11 cells ) in pt bone marrow , and 5 ) failure of pt plasma or serum to stimulate mk colony formation by normal marrow cells in a normal fashion .
C0005953
bone
C0040028
pt