1 noradrenaline and 28 imidazolidine ( clonidine-like ) and imidazoline ( oxymetazoline-like ) compounds with various phenyl ring substituents have been examined for their ability to inhibit responses to transmural stimulation and exogenous acetylcholine in ileal preparations from reserpine-treated guinea-pigs.2 the bathing solution contained propranolol , mepyramine , cimetidine and desipramine to preclude interference with the responses by other than the alpha-receptor-mediated actions of the compounds.3 in transmurally stimulated preparations the inhibitory response to noradrenaline is due to a combination of prejunctional alpha-adrenoceptor stimulation and a postjunctional depressant effect that does not involve adrenoceptor activation.4 of the 28 imidazolidines and imidazolines studied , 21 inhibited transmurally elicited responses .
C0030071
oxymetazoline
C1449836
imidazolines