we studied the cytochemical distribution of tetrahydrofolate dehydrogenase ( fh4d ) , an enzyme involved in nucleic acid metabolism and thus in cell proliferation and differentiation processes , in bone marrow blasts from 37 cases of acute lymphoblastic leukemia ( all ) , of whom 23 were pediatric patients .
C0005953
bone marrow
C0023449
acute lymphoblastic leukemia