in vitro studies on the effect of lh and prostaglandins on delta5 3beta-hydroxysteroid dehydrogenase activity using indomethacin pre-treated testis as the experimental model , revealed a greater stimulation of the enzyme activity when the incubation medium contained lh and pge2 both at a concentration of 1 microgram/ml in comparison to the effect produced by 1 microgram lh/ml alone , but the augmentory effect of pge2 on testicular response to lh was not evidenced as the lh : pge2 ratio became 1 : 10 .
C0033554
prostaglandins
C0012472
pge2