the antihypertensive effect of the fixed combination of timolol , a beta-blocking agent , hydrochlorothiazide , a thiazide diuretic , and amiloride , a potassium sparing agent , was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory african patients with previously untreated diastolic blood pressure of 95-120 mm hg .
C0002502
amiloride
C0032821
potassium