interestingly , the combination of al3+ and f- to produce the fluoro-aluminate species ( alfx ) also inhibits the gtpase of g-proteins , although the mechanism of inhibition ( e.g . binding to the g-protein.mg2+.gdp complex ) is totally distinct from that observed for free al3+ and the overall effect on signal transduction ( e.g . enhanced signal amplification ) is in complete opposition to that observed for free al3+ .
C0018296
gtpase
C0037083
signal transduction