the dna component of 5-fluoropyrimidine toxicity causes immediate growth inhibition of asynchronous s-49 cell cultures , which is self-limited within 12 hr both by the accumulation of intracellular deoxyuridine 5'-monophosphate competing for thymidylate synthetase binding and by the excretion of deoxyuridine into the cell medium which competes with 5-fluorodeoxyuridine uptake .
C0011535
deoxyuridine
C0016343
fluorodeoxyuridine