compared with normal cells , grafts repopulated with cf cells retained bioelectric responses that reflect reduced cellular permeability to chloride ions ( cl- ) : ( 1 ) greater inhibition of short circuit current ( isc ) when exposed to amiloride , ( 2 ) reduced cl- diffusion potential difference , and ( 3 ) failure of isoprenaline ( isoproterenol ) to increase isc .
C0010674
cf
C0002502
amiloride