four hours after a single intraperitoneal injection of fe-nta , 5 mg iron/kg body wt , loss of microvilli , increased number of cytoplasmic vacuoles , electron-dense cytoplasmic deposits , mitochondrial swelling , karyorrhexis , and rupture of cytoplasmic membrane were observed in proximal tubular epithelia .
C0042219
vacuoles
C0010834
cytoplasmic