overall , these results are consistent with a scheme where ( a ) both the small and larger molecular weight subunits of pde participate in alpha t-pde interactions , ( b ) the activation of pde by the alpha t.gtp gamma s ( or alpha t.gtp ) species does not result in the complete dissociation of the gamma subunit from the enzyme , and ( c ) the deactivation of this signal transduction system results from a direct interaction between the alpha t.gdp species and the catalytic moiety of the effector enzyme .
C0079469
gtp gamma s
C0018353
gtp