methotrexate ( mtx ) and aminopterin ( amt ) analogues containing l-homocysteic acid or l-cysteic acid in place of l-glutamic acid were synthesized and tested as inhibitors of dihydrofolate reductase from l1210 cells and folyl polyglutamate synthetase from mouse liver .
C0025677
methotrexate
C0002583
aminopterin