after pretreatment with diltiazem ( 0.3 mg/kg iv ) and propranolol ( 1.0 mg/kg iv ) , sufentanil ( 25 micrograms/kg iv ) produced significantly greater bradycardia ( 38 +/- 4 beats/min ) than it did in non-pretreated or propranolol-pretreatment dogs .
C0428977
bradycardia
C0033497
propranolol