the phosphopeptide arg-arg-ala-ser ( 32p ) -val-ala however , reproducing the phosphorylation site of pyruvate kinase and previously phosphorylated by camp-dependent protein kinase , can be very readily dephosphorylated with favourable kinetic constants ( km 0.28 microm , vmax = 62 units/micrograms ) while its derivatives ala-ser ( 32p ) -val-ala , arg-arg-ala-thr ( 32p ) -val-ala , arg-arg-pro-ser ( 32p ) -pro-ala as well as other peptides and protein substrates phosphorylated by either protein kinase-c or casein kinase-2 are either unaffected or very slowly dephosphorylated by the phosphatase .
C0031715
phosphorylation
C0034348
pyruvate kinase