the rate and profile of formation of these metabolites is species-dependent.5 13,14-dihydro-15-keto prostaglandin f ( 2alpha ) is the principal prostaglandin f series metabolite in all species.6 pig and guinea-pig kidney contain an unidentified enzyme which converts 13,14-dihydro-15-keto prostaglandin f ( 2alpha ) to 13,14-dihydro prostaglandin f ( 2alpha ) .7 rat kidney contains a high concentration of a prostaglandin 9-hydroxy dehydrogenase which converts 13,14-dihydro-15-keto prostaglandin f ( 2alpha ) to 13,14-dihydro-15-keto prostaglandin e ( 2 ) .8 rabbit kidney contains a novel 9-hydroxydehydrogenase which oxidises prostaglandin f ( 2alpha ) directly to e ( 2 ) , thus producing a compound with more potent renal actions .
C0033554
prostaglandin
C0033559
prostaglandin e