evidence suggesting that the new genes encode tissue-specific transcriptional factors and belong to the same regulatory cascade as the other paired domain genes includes ( i ) tissue-specific expression of pox meso in the somatic mesoderm and of pox neuro in the central and peripheral nervous system , ( ii ) nuclear localization of their proteins , ( iii ) dependence on prd activity and ( iv ) presence of the paired domain in genes of known regulatory activity .
C0040648
transcriptional factors
C0017362
genes