recent observations reveal deficiencies in the accepted theory rationalizing the biological activities of the beta-lactam antibiotics , since a study of strained carbapenem beta-lactams has shown that the observed antibacterial activities do not correlate either with the pyramidal character of the beta-lactam nitrogen atom or with the ease of base hydrolysis of the lactam amide bond .
C0026458
beta-lactam antibiotics
C0282215
beta-lactam