we discuss the pathogenesis of the clinical and pathologic ocular findings with regard to the inherited absence of the enzymes hexosaminidase a and b and an accumulation of the substrates , gm2 ganglioside and asialo gm2 , in the nervous system ( including retina and optic nerve ) and globoside and other hexosamine-containing substances in the viscera ( including cornea ) .
C0027763
nervous system
C0029130
optic