although tolbutamide inhibited 86rb efflux from glucose-deprived islets , whether in the absence or presence of extracellular ca2+ or ouabain , a primary action of the sulfonylurea on the ca2+-responsive k+ channels appeared unlikely , because tolbutamide failed to suppress the increase in 86rb outflow evoked by either the ionophore a23187 or ouabain .
C0038766
sulfonylurea
C0040374
tolbutamide