withdrawal of perifusate chloride or bicarbonate and the application of the drugs 4-acetamido-4'-isethiocyanostilbene-2,2'-disulfonic acid ( sits ) and probenecid , both blockers of transmembrane anion movement , have been used to establish that a chloride-bicarbonate exchange system is operative in the cell membrane and that it is one of the control mechanisms of phi .
C0003075
anion
C0008203
chloride