in a cohort of 268 type i diabetic patients , aged 19.6 +/- 4.1 years ( mean +/- 1 sd ) , with a diabetes duration of 10.4 +/- 4.9 years , treated by the same team , using the same conventional treatment regime during the total observation period , the progression rate of early retinopathy within the first two decades of diabetes was deduced from observed transitions of the retinal status from one stage of retinopathy ( as defined by fluorescein angiography ) to a higher one ( malone et al. , 1977 ) within one year .
C0035298
retinal
C0035309
retinopathy