in the presence of nadh , the optimal ph for the enzyme was 7.7 and the apparent michaelis constants of the enzyme for progesterone and pregnenolone at 37 c and ph 7.4 were 6.9-7.1 x 10-6m and in the order of 10-5m , respectively , 17alpha , 20beta-dihydroxypregn-4-en-3-one was the only significant metabolite produced from 17alpha-hydroxyprogesterone by microsomal fraction of the human testis in the presence of nadh .
C0033308
progesterone
C0020387
17alpha-hydroxyprogesterone