subsequent to src kinase-mediated tyrosine phosphorylation , the insulin receptor , either immobilized on insulin-agarose or in detergent extracts , exhibits a 2-fold increase in associated kinase activity using histone as substrate . src kinase mediates phosphorylation of predominantly tyrosine residues on both alpha and beta subunits of the insulin receptor .
C0282625
src kinase
C1519726
phosphorylation