thus , though il2 gene activation , synthesis or release apparently can be activated via at least two pathways : t cell receptor or thy-1 , it seems that activation of the genes responsible for synthesis and release of the helper factors , which ensure antigen-specific b cell proliferation and differentiation , needs th cell-b contact mediated via the antigen-specific t cell receptor .
C0879590
il2 gene
C1155008
b cell proliferation