four cytoplasmically synthesized rat liver mitochondrial enzymes , located either as soluble enzymes in the mitochondrial matrix ( l-glutamate dehydrogenase and malate dehydrogenase or in the intermembrane space ( sulfite oxidase ) or as an integral membrane protein located on the matrix face of the inner mitochondrial membrane ( d-beta-hydroxybutyrate dehydrogenase ) , were all shown to be synthesized as precursors larger than their mature counterparts by 1000-6000 daltons .
C0026237
mitochondrial
C1510421
mitochondrial matrix