a diagnosis of encephalitis was considered on early eeg evidence ( stereotyped repetitive sharp wave bursts ) and was confirmed by isolation of echo 5 virus from brain specimen , and ultrastructural observation of characteristic cytopathic effect ( disappearance of organelles , proliferation of smooth membranes ) and of probable viral particules in astrocytes , without any inflammatory process .
C0014038
encephalitis
C0006104
brain