the inhibition of cellular replication and the induced maturation produced by these agents appears to be a consequence of the inhibition of imp dehydrogenase , since growth inhibition is partially reversed and differentiation is completely prevented by the simultaneous exposure of cells treated with inhibitors of imp dehydrogenase to exogenous guanosine , which serves to circumvent the effects of the blockage of imp dehydrogenase .
C0007589
differentiation
C0007634
cells