the administration of inosine dosed 25 mg/kg daily during 10 1/2 months prevented the development of excentric cardiac hypertrophy on the background of experimental aortic stenosis in rats , reduced the lowering of the working capacity of the animals , and partially inhibited the full development of functional and morphological myocardial changes , detected by electrocardiographic , vectorcardiographic , microscopic , and electronmicroscopic examinations .
C0018787
cardiac
C0027061
myocardial