since rheumatic valvulitis may play a subordinate role , in contrast to etiologies such as myxomatous degeneration of the mitral valve , rupture of chordae tendineae , papillary muscle dysfunction due to coronary artery disease and other causes , left ventricular function is generally determined by the adaptations of the myocardium to the volume overload , or to ischemia or infarction from coronary artery disease rather than to a concomitant myocarditis .
C0022116
ischemia
C0021308
infarction