we have recently proposed that a third component , once affected by adp binding , induces a conformational transition of the fibrinogen receptor from the low to the high affinity state , which is responsible for platelet aggregation [ de cristofaro , r. , landolfi , r. , castagnola , m. , de candia , e. , di cera , e. , & wyman , j . ( 1988 ) proc . natl . acad . sci . usa 85 , 8473-8476 ] .
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C0041703
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