phenotypic , molecular , and cellular genetic data favor the presence of a myeloma stem cell early in hematopoietic development so that , as in chronic myelogenous leukemia ( cml ) , a far distance exists between the primordial malignant cell that was the target of malignant transformation and the dominant clinical phenotype .
C0023473
chronic myelogenous leukemia
C0334227
malignant cell