d-penicillamine , an antirheumatic drug having chelating ability , was investigated for the effects on vitamin b6 and metals at doses ranging from 25 to 600 mg per kg , p.o. , or in case of the highest dosing of d-penicillamine , together with s.c. administration of cupric sulfate or pyridoxine hydrochloride for 28 days in rats .
C0087162
vitamin b6
C0700496
pyridoxine hydrochloride