these results are consistent with the idea that , like heme deprivation , the activation by ca2+ and phospholipid promotes the first step of the reaction pro-inhibitor in equilibrium reversible inhibitor leads to irreversible inhibitor and suggest that , in the presence of hemin albeit by a different mechanism , this activation affects the same inhibitor that is activated in the absence of heme -- namely , hci .
C0018988
hemin
C0018966
heme