the synergic effects on hela cells between 1-hexylcarbamoyl-5-fluorouracil ( hcfu ) , a lipophilic masked compound of 5-fluorouracil ( 5-fu ) , and hyperthermia were investigated , with the following results : ( 1 ) after the cells had been exposed to the drug at 77 microm for 1 , 2 or 3 days , with or without heat ( 43 degrees c ) for 2 h , treatment with hcfu and heat inhibited cell growth by 9.2 % on day 3 , compared to control cells , hcfu alone , heat alone or the combined treatment with 5-fu plus heat .
C0007595
cell growth
C0007634
cells