analysis of mortality trends in 21 countries indicates that , since oral contraceptives first became available , changes in mortality from non-rheumatic heart-disease and hypertension ( i.c.d . 400-429 ) , cerebrovascular disease ( i.c.d . 430-439 ) , and all non-rheumatic cardiovascular diseases ( i.c.d . 400-469 ) among women aged 15-44 years have been strongly associated with changes in the prevalence of oral-contraceptive use in each country .
C0035439
rheumatic
C0007226
cardiovascular