we report herein that , when granulocytes are `` '' primed '' '' by a 90-min preincubation with the recombinant human hemopoietic growth factor granulocyte-macrophage colony-stimulating factor ( gm-csfrh ) , elevation of the concentration of cytosolic ca2+ ions ( [ ca2+ ] i ) becomes a more effective transduction signal capable of triggering the generation of substantial quantities of superoxide ( o2- ) anions by the cell .
C0022023
+ io
C0003075
) anio