using the quantitative-histochemical evaluation of the cholinergic marker enzyme acetylcholinesterase ( ache ) in the epithalamus ( nucleus medialis habenulae ) and in different cortical areas of rats during postnatal ontogenesis it is shown that ( i ) the cholinergic differentation in the thalamic structure seems to be already finished immediately after birth and ( ii ) the cholinergic synaptogenesis in the cerebral cortex does not start until birth , but takes place postnatally in phylogenetic graduated cortices in temporal echeloned steps ( paleo- greater than archi- greater than neocortex ) .
C0152361
epithalamus
C0039729
thalamic structure