these results indicate that anomalies comparable to those seen in the infants of mothers treated with isotretinoin , 13-cis retinoic acid , during pregnancy can also be induced in mice and suggest that the site affected by ra may be neural crest cells , including those in the cephalic and caudal regions , and cells committed to somitic mesoderm in the trunk region .
C0022265
13-cis
C0032961
pregnancy