our data suggest ( i ) that differences in early demyelinating activity by the choline lysophospholipids are related to their rate of turnover , as highest activity was associated with the agents that are not metabolized by lysophospholipase ( e.g. , alkyl-ppc ) or lysolecithin acyltransferase ( e.g. , 3-acyl-gpc ) , ( ii ) that the lysopc molecule as such and not its products of catabolism causes demyelination , and ( iii ) that demyelinating activity is not due to the general detergent action of lysopc , but rather that specific interactions appear to trigger the processes of demyelination induced by lysophospholipids .
C0024360
lysopc
C0024367
lysophospholipids