we report that approximately 1/4 of monoclonal rheumatoid factors produced by hybridomas derived from fusions of spleen cells from mrl/lpr/lpr mice with systemic lupus erythematosus ( sle ) and arthritis exhibited multiple reactivities with other autoantigens , including ddna , histones , and/or cytoskeletal-cytoplasmic elements .
C0010853
cytoskeletal
C0010834
cytoplasmic