four aspects for the use of plc/prf/5 cell line as an alternative source of hbsag for hepatitis b vaccine production were assayed in this study : improvement in hbsag production with chemical inducers , tests for the presence of hepatitis b virions , antigenic topology of hbsag polypeptides and immunogenicity of hbsag in guinea pigs .
C0062527
hepatitis b vaccine
C0019163
hepatitis