after adjustment for these factors , low peak expiratory flow rate was associated with chronic respiratory symptoms ( cough , wheeze , shortness of breath , exertional dyspnea , orthopnea , and paroxysmal nocturnal dyspnea ; p less than 0.0001 ) and with certain cardiovascular variables ( history of stroke , p = 0.0014 ; angina , p = 0.05 ; and high pulse rate , p = 0.004 ) .
C0007226
cardiovascular
C0039231
high pulse rate