since repeated treatments with these agents before or after initiation with a single subcarcinogenic dose of 7,12-dimethylbenz [ a ] anthracene ( dmba ) did not alter significantly the development of skin tumors ( curtis et al . ; perchellet and boutwell ) , the present results suggest that , in the two-step initiation-promotion protocol , both ibmx and cyclic amp treatments may decrease specifically the promoting stimulus of skin carcinogenesis .
C0037286
the
C0037267
the