or ( c ) increased presynaptic inhibition of primary afferents by a direct action.2 baclofen ( 9.4-70.3 mumol/kg , i.p . ) , which may mimic spinal presynaptic inhibition , produced a dose-dependent increase in the response times of mice in a hot-plate test , but high doses also impaired motor function.3 morphine hydrochloride ( 5.3-40 mumol/kg , i.p . ) increased the response time of mice in the hot-plate test and had little effect on motor function.4 combination of baclofen ( 9.4 or 23.4 mumol/kg ) with morphine ( 13.3 mumol/kg ) produced greater increases in response time than either drug administered alone but with little concurrent effect on motor function.5 the possibility that baclofen may have some analgesic action and a potentiating effect on other analgesics is discussed .
C0770901
morphine hydrochloride
C0026549
morphine