moreover , this desensitization process appears to be heterologous , because alpha 2-adrenergic agonists ( e.g. , clonidine or norepinephrine ) and the muscarinic agonist ( carbachol ) exhibited significantly lower potency for inhibiting cyclase activity when compared to untreated cultures .
C1373110
alpha 2-adrenergic
C0009014
clonidine