in order to test this hypothesis , the effect of agents capable of altering the activation of aa including cytochrome p-450 inducers and inhibitors , cobaltous chloride which decreases the amount of p-450 , prostaglandin synthetase inhibitors ( indomethacin and naproxen ) , antioxidants ( butylated hydroxyanisole , alpha-tocopherol , ascorbic acid and ascorbic acid palmitate ) and other chemicals known to decrease aa hepatotoxicity ( dimethylsulfoxide and cysteamine ) , on the biliary excretion of aa-gs was studied in hamsters , the species most sensitive to aa-induced hepatotoxicity .
C0003968
ascorbic acid
C0049690
ascorbic acid