we have found that when the concentration of brain ach and ch is increased to a new steady state as a result of oxotremorine and physostigmine injections the turnover rate of brain ach decreases from 0.34 mumol/g/hr ( in saline-treated mice ) to 0.12 and 0.061 mumol/g/hr , respectively .
C0086045
concentration
C0006104
brain