fine structural changes in the sarcoplasmic reticulum ( sr ) in myocardial ischemia , induced by occlusion of the anterior descending branch of the left coronary artery in the canine heart , were studied by the freeze-fracture technique in situ and in vitro and compared to the alterations in ca2+-stimulated atpase activity and sodium dodecyl sulfate gel electrophoresis of the isolated sr .
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