these findings are in line with the proposal that circulating noradrenaline reaches every hepatocyte , causing a clear overall increase of inositol phosphate formation and thus calcium release from the endoplasmic reticulum , while the hepatic nerves reach only a few cells causing there a small local change of inositol phosphate metabolism and thence a propagation of the signal via gap junctions .
C0014239
endoplasmic reticulum
C0007634
cells