the following features of tdm of tcas are reviewed : ( 1 ) the relationships between tca concentration in plasma and the multiple pharmacologic actions and clinical effects of tcas , ( 2 ) the use of tdm to improve antidepressant efficacy while avoiding both cardiac and brain toxicity , ( 3 ) the protocol to follow when using tdm of tcas and the rationale behind it , and ( 4 ) common laboratory errors that can be readily avoided but that could otherwise lead to spurious results .
C0086045
concentration
C0006104
brain