following incubation of the labeled hormone with reconstituted cytosol-chromatin at 0 degrees , 1alpha,25-dihydroxy [ 3-h ] cholecalciferol is primarily associated with the cytoplasmic receptor , after shifting the incubation temperature to 25 degrees , a progressive increase in the concentration of the nuclear receptor complex and a concomitant decrease in the concentration of the cytoplasmic binding component occur .
C0206588
nuclear receptor
C0010834
cytoplasmic