in the rat , et-1 ( 0.1-0.4 nmol/kg i.v . ) induced a biphasic effect on arterial blood pressure ( bp ) , with a transient fall being followed by a rise , which was unaffected by indomethacin pretreatment , whereas i.v . infusion of et-1 induced only an increase in bp .
C0079281
et-1
C0079284
et-1