taken together our results suggest that 1 ) the 5 s er is a homodimer of two mr congruent to 66,000 hormone binding subunits which may be released as such from the nontransformed 8-9 s er , 2 ) the trypsin digestion products yield two carboxyl-terminal fragments of mr congruent to 30,000 that remain in the form of a dimer having lost their dna-binding region , and 3 ) the trypsin cleavage would occur within the region located between the hormone-binding domain and the dna-binding domain .
C0034804
er
C1148673
dna-binding