ly 165163 decreased whole brain concentrations of the serotonin metabolite , 5-hydroxyindoleacetic acid , but not of serotonin itself , decreased the rate of accumulation of 5-hydroxyindoleacetic acid after probenecid administration to block its efflux from brain , decreased the rate of decline in serotonin concentration after inhibition of serotonin synthesis with alpha-propyldopacetamide and decreased the accumulation of 5-hydroxytryptophan after decarboxylase inhibition by m-hydroxybenzylhydrazine .
C0006104
brain
C0086045
concentration