recent studies in our laboratory and others have demonstrated that dna polymerase inhibitors such as the ara nucleosides , aphicolin and dideoxythymidine are potent inhibitors of the dna excision repair process in confluent human fibroblasts as evidenced by the agent-dependent accumulation of single-strand interruptions in the dna of uv-irradiated , but not in unirradiated , cellular dna .
C0016030
fibroblasts
C0007634
cellular