in these patients we demonstrated that ( a ) cml with a breakpoint in the bcr region without cytogenetically detectable ph chromosome is characterized by the same genomic recombination of 5'-bcr and c-abl as cml with standard ph translocation and ( b ) unusual localization of 5'-bcr and c-abl sequences caused by complex ph translocation does not interfere with transcription of the bcr-abl fusion gene .
C0023473
cml
C1835417
bcr-abl fusion gene