however , concurrent treatment with saccharin ( 50 micrograms/ml , nontoxic dose ) and mnu or enu ( 29 micrograms/ml or 44 micrograms/ml , respectively ) was effective in inducing transformation ( greater than 300 colonies/10 ( 5 ) cells ) , but only when the cells were treated with saccharin after being released from a g1 block ( amino acid deprivation ) and followed by mnu or enu treatment in early s phase .
C0007634
cells
C1517342
g1 block