these cells secreted elevated levels of both egf-like factors and tgf-beta , suggesting that the lack of responsiveness of these cells to exogenous growth factors arose from autocrine stimulation . myc-transfected cells displayed conditional anchorage-independent growth : they formed numerous colonies in soft agar in the presence of egf but relatively few colonies in the presence of pdgf or tgf-beta .
C1327616
secreted
C0007634
cells