brain and serum concentrations of 6,7-adtn after 100 mumol/kg db-6,7-adtn , determined during catechol-o-methyltransferase ( comt ) inhibition by tropolone , were 5 -- 7 times higher than those during normal comt activity , thus equalling 5,6-adtn concentrations after 100 mumol/kg db-5,6-adtn .
C0006104
brain
C0086045
concentrations