intracellular gm2 increased five- to fifteen-fold in all of the gm2 gangliosidosis cell lines tested , including those from patients with infantile tay-sachs disease ( tsd ) , sandhoff disease , late infantile and juvenile variants of tsd with high residual enzyme activity , adult onset gm2 gangliosidosis , and the ab-variant .
C0268274
gm2
C0036161
sandhoff disease