these results suggest that ( 1 ) the pre-ovulatory lh surge begins between midnight and 0800 h in the majority of women , ( 2 ) luteinization of the granulosa cells within the pre-ovulatory follicle occurs in response to the lh surge , ( 3 ) the increase in prolactin at the time of the lh surge is not directly related to increasing levels of oestradiol but may be due to a decrease in hypothalamic inhibition of prolactin secretion which occurs coincident with the release of lhrh associated with the preovulatory lh surge .
C0020663
hypothalamic
C0023610
lhrh