the acidification defect of vpl3 and vpl6 mutants correlated with a marked deficiency in vacuolar atpase activity , diminished levels of two immunoreactive subunits of the protontranslocating atpase ( h+-atpase ) in purified vacuolar membranes , and accumulation of the intracellular portion of pra as the precursor species .
C0379099
vacuolar atpase
C0018437
h