intravenous administration of bsa into 3-month-old rabbits producing detectable anti-bsa antibody only of the ige class of immunoglobulin induced a variety of intravascular blood coagulation alterations observed in the plasma 15 min after antigen challenge included : a ) the intravascular consumption of intrinsic blood coagulation factors xii , xi , and ix and possibly the reduction in clottable fibrinogen ;
C0005778
coagulation
C0015525
blood