it appears , therefore , that there is no qualitative difference between the enzyme obtained from leukocytes of patients with chronic myelogenous leukemia and the enzyme obtained from normal leukocytes , suggesting that the difference in total cell activity is due to an actual decrease in amount of enzyme in chronic myelogenous leukemia or to a mixed cell population , one with a normal quantity of enzyme and the other with little or no active enzyme . ( 4 ) in both the normal cell and the leukemic cell extracts , transferase and phosphorylase activities could not be separated .
C0023473
chronic myelogenous leukemia
C1517806
leukemic cell