Antisense treatment significantly reduced (by approximately 50%) the volume of water drunk in response to i.c.v. injection of renin or subcutaneous isoproterenol, but did not reduce water intake elicited by the other dipsogenic stimuli.The i.c.v. administration of mismatch, scrambled or sense oligonucleotides did not inhibit water intake.
C0001969
Alcoholic Intoxication