Using a weighted regression analysis implemented in the program SCORE-Seq, we found a rare variant constellation across the entire NKAIN1-SERINC2 region that was associated with alcohol dependence in European-Americans (Fp: overall, P=1.8&#215;10(-4); VT: overall, P=1.4&#215;10(-4); Collapsing, P=6.5&#215;10(-5)) and European-Australians (Fp: overall, P=0.028; Collapsing, P=0.025), but not in African-Americans, and not associated with any other disorder examined.
C0001973
Alcoholic Intoxication, Chronic