As effective as other brands; bit harder to peel off the backing; wasteful packaging [SEP] These patches work as well as other patches I've tried. They are not a miraculous cure-all, but they do help flatten out the acne and draw out the stuff that needs to be drawn out (don't want to get too gross and graphic here). They are small (1 cm diameter) so the coverage is limited, but they adhere well.<br /><br />There are a couple of cons with these that lower my score:<br /><br />> They are harder to peel off the backing than others, and it's easy to fold over the edge of the patch when removing it, making it less effective. Other brands I've used have slits in the backing material, making it much easier to dispense a patch without damaging it.<br /><br />> The packaging is very wasteful. Each sheet of 20 comes in its own box. You could easily fit several sheets into one box. Either the box should be made much smaller or each box should hold multiple sheets. There's no need for all this packaging waste.<br /><br />Three stars (average). While these work as well as other patches, there are other options that are better choices.