Iyini i-epigenomics?
I - epigenomics iwukufunda ngesethi ephelele yezinguquko ze - epigenetic ezintweni zofuzo zamangqamuzana, ezaziwa ngokuthi i - epigenome. Le nkambu iyafana ne-genomics ne-proteomics, okuyizo izifundo ze-genome ne-proteome yeseli. Izinguquko ze-epigenetic yizinguquko eziguquguqukayo ku-DNA noma kuma-histone eseli ezithinta ukubonakaliswa kofuzo ngaphandle kokushintsha ukulandelana kwe-DNA. Ukugcinwa kwe-epigenomic kuyinqubo eqhubekayo futhi kunendima ebalulekile ekusimameni kwama-eukaryotic genomes ngokubamba iqhaza ezindleleni ezibalulekile zokuphila njengokulungiswa kwe-DNA. Kuthiwa ama - flavone ezitshalo avimbela izimpawu ze - epigenomic ezibangela umdlavuza. Izinguquko ezimbili ze-epigenetic ezibonakala kakhulu yi-DNA methylation kanye nokuguqulwa kwe-histone. Izinguquko ze-epigenetic zidlala indima ebalulekile ekubonakalisweni nasekulawulweni kwezakhi zofuzo, futhi zibandakanyeka ezinqubweni eziningi zamaseli ezinjengokuhlukaniswa / ukuthuthukiswa kanye ne-tumorigenesis. Ukucwaninga nge-epigenetics ezingeni lomhlaba wonke kuye kwenzeka muva nje ngokulungiswa kwezivivinyo ze-genomic high-throughput.