Waa maxay waqtiga nus-ka-noqoshada ee Iodine-125?
Context:Iodine-125 (125I) waa radioisotope of iodine kaas oo loo isticmaalo baaritaanka bayoolajiyada, sawir qaadista daawada nukliyeerka iyo daaweynta shucaaca sida brachytherapy si loo daweeyo xaalado dhowr ah, oo ay ku jiraan kansarka qanjirka 'prostate', uveal melanomas, iyo burooyinka maskaxda. Waa radioisotope-ka labaad ee ugu cimriga dheer ee iodine, ka dib iodine-129. Kala badh noloshiisu waa 59.49 maalmood wuxuuna ku baaba'aa qabashada elektaroonigga ilaa xaalad kicin ah oo ah tellurium-125. Xaaladdaani ma ahan 125mTe ee metastable, laakiin waa xaalad tamar hoose oo isla markiiba ku baaba'da gamma oo leh tamar ugu badnaan 35 keV. Qaar ka mid ah tamarta dheeriga ah ee 125Te ee la soo kiciyay ayaa laga yaabaa inay gudaha u beddelaan elektaroonno la soo saaray (sidoo kale 35 keV), ama x-rays (laga bilaabo electron bremsstrahlung), iyo sidoo kale wadar ahaan 21 Auger electrons, kuwaas oo lagu soo saaray tamar hooseeya oo ah 50 ilaa 500 electron volts. Ugu danbeyntii, 125Te oo ah xaalad xasilooni ah ayaa la soo saaraa oo ah badeecada ugu dambeysa ee kala go'a. Isbedelka gudaha iyo Auger electrons waxay keenaan waxyeelo yar oo ka baxsan unugyada oo ay ku jiraan atomka isotope. X-rays iyo gamma rays waxay leeyihiin tamar hoose oo ku filan si ay u gaarsiiyaan qiyaasta shucaaca ee sare si xushmad leh unugyada u dhow, ee "joogtada ah" brachytherapy halkaas oo kaabsoosha isotope ay ku sii jiraan (125I waxay la tartamaysaa palladium-103 isticmaalka noocan oo kale ah) Sababtoo ah nuska noloshiisu aad u dheer tahay iyo soo saarida foton tamar yar oo lagu ogaan karo gamma-counter crystal detectors, 125I waa isotope la doorbido oo loogu talagalay in lagu calaamadeeyo unugyada difaaca jirka ee tijaabada shucaaca iyo hababka kale ee gamma-counting ee ku lug leh borotiinka ka baxsan jirka. Isotope-ka isla astaamaha ayaa ka dhigaya mid waxtar u leh brachytherapy, iyo hababka baaritaanka daawada nukliyeerka qaarkood, halkaas oo ay ku xiran tahay borotiinnada (albumin ama fibrinogen), iyo halka nus-nolosha ka dheer tan ay bixiso 123I ayaa loo baahan yahay baaritaanka baaritaanka ama baaritaanka shaybaarka dhowr maalmood. Iodine-125 waxaa loo isticmaali karaa in lagu baaro/sawir qaato qanjirka thyroid, laakiin iodine-123 ayaa loo doorbidayaa ujeedadaas, sababtoo ah irradiation-ka ayaa si fiican u galaya iyo nus-nolosha gaaban (13 saacadood). 125I waxay faa'iido u leedahay baaritaanka heerka shaandhaynta glomerular (GFR) ee lagu ogaanayo ama la kormeero bukaannada qaba cudurka kelyaha. Iodine-125 waxaa loo isticmaalaa daaweynta brachytherapy ee daaweynta burooyinka. Daawada shucaaca ee unugyada nuugaya iodine (sida qanjirka thyroid), ama nuugaya dawooyinka shucaaca ee ay ku jiraan iodine, beta-emitter iodine-131 waa isotope la doorbido.
Waqtiga nuska ee iodine-125 waa 59. 49 maalmood.