Iyini i - epistatis?
I-epistasis iyisimo sezakhi zofuzo lapho umphumela wokuguquka kwezakhi zofuzo uncike ebukhoneni noma ekungabikho kokuguquka kwezakhi zofuzo kwelinye noma kwamanye ama-gene, abizwa ngokuthi ama-gene aguqulayo. Ngamanye amazwi, umphumela wenguquko yokuguquka kwezakhi zofuzo uncike kulokho okuvelayo. Ngakho-ke, ukuguquka kwe-epistatic kunemiphumela ehlukile uma kwenzeka kukodwa kunangesikhathi kwenzeka ndawonye. Ekuqaleni, igama elithi epistasis lalisho ukuthi umphumela wohlobo oluthile lofuzo ufihlwa yilowo wohlobo oluhlukile.  Umqondo we - epistasis waqala ngo - 1907 kwezofuzo kodwa manje usetshenziswa kwezokuthakwa kwamakhemikhali ezinto eziphilayo, kwezokubalwa kwezinto eziphilayo nakwezokuthuthuka kwezinto eziphilayo. Lesi simo sibangelwa ukusebenzelana phakathi kwezakhi zofuzo (njengezinguquko ezidingekayo nakulawula ukubonakaliswa kwezakhi zofuzo) noma ngaphakathi kwazo (izinguquko eziningi ezidingekayo ngaphambi kokuba i-gene lilahlekelwe umsebenzi), okuholela emiphumeleni engeyona eqondile. I-epistasis inomthelela omkhulu ekwakhekeni kwezwe lokuziphendukela kwemvelo, okuholela emiphumeleni ejulile yokuziphendukela kwemvelo kanye nokuguquguquka kwezimpawu ze-phenotypic.