Kuyini ukuvuselelwa kwe-CRISPR/Cas9 okuqondiswe ku-allele ethile (i-TASCA)?
Uhlelo lwe-CRISPR/Cas9 luyitheknoloji yokuhlela izakhi zofuzo evumela ukuguqulwa ngokunembile kokulandelana kwe-DNA ye-genome. I-Targeted Allele-Specific CRISPR/Cas9 Activation (i-TASCA) yenza abacwaningi bakwazi ukuvula i-gene ethile ngaphakathi kwe-genome ngokukhomba ukulandelana okuthile kwe-DNA nokukhuthaza ukubonakaliswa kwe-gene oyifunayo.  I-TASCA ingasetshenziswa ezinhlotsheni ezihlukahlukene zezicelo, njengokwelashwa kwezakhi zofuzo, ukutholwa kwemithi, nocwaningo oluyisisekelo ngokusebenza kwezakhi zofuzo. Inikeza ithuluzi elinamandla lokutadisha indima yezakhi zofuzo ezithile ezinqubweni zamaseli nasezifweni.