Chii chinonzi connectomics?
Connectomics ndiko kugadzirwa nokudzidzwa kweconnectomes: mepu dzakakwana dzezvisungo mukati mehurongwa hwetsinga dzomuviri. Kazhinji kazhinji, inogona kurangarirwa sechidzidzo chewiring wiring diagrams nekutarisa kuti kubatana kwechimiro, synapses yega yega, cellular morphology, uye cellular ultrastructure zvinobatsira sei kugadzira network. Masisitimu etsinga mubatanidzwa wakaumbwa nemabhiriyoni ezvibatanidzwa uye izvi zvibatanidzwa zvine mutoro wezvatinofunga, manzwiro, zviito, ndangariro, kushanda uye kusashanda zvakanaka. Naizvozvo, fundo yeconnectomics ine donzo rokufambisira mberi nzwisiso yedu yeutano hwepfungwa nokuziva kupfurikidza nokunzwisisa kuti masero ari musystem yetsinga anobatanidzwa sei nokukurukurirana. Nemhaka yokuti zvivako izvi zvakaoma zvikuru, nzira dziri mumunda uyu dzinoshandisa kushandiswa kwepamusoro-kubudiswa kwekushanda uye kugadzirwa kwemasikirini ekufananidzira, kazhinji magnetic resonance imaging (MRI), electron microscopy, uye maitiro ehistological kuitira kuti kuwedzere kukurumidza, kubudirira, uye kugadziriswa kwemamapu aya ehurongwa hwepfungwa. Kusvika pari zvino, makumi ezviuru emadhata akaunganidzwa akafukidza hurongwa hwepfungwa kusanganisira nzvimbo dzakasiyana-siyana dzecortex, cerebellum, retina, peripheral nervous system uye neuromuscular junctions.  Kazhinji kutaura, kune marudzi maviri econnectomes; macroscale uye microscale. Macroscale connectomics inoreva kushandisa mashandiro uye mashandiro eMRI dhata kuti iite mepu yakakura yefibre uye inoshanda nzvimbo dzegrey mukati meuropi maererano nekuyerera kweropa (kushanda) uye mvura diffusivity (yakagadzirwa). Microscale connectomics ndiko kuiswa kwemepu yezvose zvinobatanidza zvipenyu zviduku zvichishandisa microscopy uye histology. Ndokunge, kubatana kwose kuripo muhurongwa hwavo hwepakati hwetsinga.