Iyini i-enzyme inhibitor?
I- enzyme inhibitor iyinhlanganisela ye- molecule ebopha indawo esebenzayo ye- enzyme, noma enye indawo ku- enzyme, futhi ivimbe i- enzyme's catalysis yokusabela. Ngokuvamile ama- enzyme inhibitors akhethekile ku- enzyme eyodwa futhi alawula umsebenzi waleyo enzyme. Zilawula nama - enzyme abalulekile njengama - protease noma ama - nuclease okuthi uma engalawulwa, alimaze iseli.  Ubuthi obuningi obuvezwa izilwane noma izitshalo buyi-enzyme inhibitors, futhi ama-molecule amaningi emithi ayi-enzyme inhibitors evimbela i-enzyme yabantu engajwayelekile noma i-enzyme ebalulekile ekusindeni kwe-pathogen. Njengoba ngokuvamile ama-anti- pathogen inhibitors ehlasela i- enzyme eyodwa kuphela, imithi enjalo iqondene kakhulu futhi ngokuvamile ayinawo imiphumela emibi kubantu.  Ngokuvamile izidakamizwa ezivimbela ama- enzyme zinama- dissociation constants aphansi, okusho ukuthi inani elincane le- inhibitor lizovimbela i- enzyme. Ukutholakala kwama - enzyme inhibitor nokucwengwa kwawo kucwaningwa emkhakheni we - biochemistry nowokuthakwa kwemithi.