<s>[INST] I had a tongue biopsy a few months ago, and the lesion has returned along the border of the previous. I followed up with the NP a couple weeks later, but she said she didn't understand the results, and would get back in contact with me. Unfortunately I have not heard back since. She told me that it said squamous cell mucosa with granulomas. I am having pain from the lesion, therefore having a hard time sleeping, and was curious if anyone could give me some insight as to what may be going on. [/INST] Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. It looks like granuloma formation that can be due to infection and inflammation..So first of all consult an Oral Surgeon and get evaluated so that they can check the report and if needed another Biopsy can be done for confirmation..For now you can apply Lidocaine gel over the lesion so that the pain can subside..Along with it you can take anti inflammatory painkillers like Ibuprofen.You can do warm saline gargles and antiseptic mouthwash gargles.Do cool compresses over the lesion to reduce inflammation..However you should consult an Oral Physician/ Surgeon immediately so that appropriate treatment can be advised.Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Honey Arora </s>