<s>[INST] My father is suffering from an aplastic anemia from more than one years,he had taken cyclosporine approx 8 months due to medicine side effect his cretaine level increase to 2.6. now doctor stop the medicine and they advice to take menabol. please suggest me that he can take Menabol or not.please mail me in this email id:- YYYY@YYYY Regards, Tej Kumar Singh [/INST] Dear Tej, The first question is whether the creatinine has come down to normal after stopping cyclosporin. If it has come down to normal, then cyclosporine may be restarted by an experienced hematologistat a lower dose and the dose may be gradually titrated. If the creatinine rises again, then alternative drugs like Menabol may be tried but remember Menabol has less efficacy. </s>