<s>[INST] Hello doctor, My wife is 24 years old and she has PCOD. We have been trying to conceive for the past 2 years, but no result. We went to infertility specialist six months ago. He started the treatment through medicines and one IUI. But, all the treatments failed. Then, he decided to go for IVF. Our doctor said that my semen sample is normal. In this IVF cycle 15 eggs were retrieved. Out of the 15 eggs they decided 8 eggs for IVF and 7 eggs for ICSI. Later, the doctor said that all 8 IVF eggs failed to be fertile because egg layer was very strong and And all the 5 eggs with ICSI are fertile. He transferred two embryos today and said that the embryo quality is good. Is ICSI a safe process? Will it affect the IQ of the baby or cause any birth defect? What about the fertility status during their adulthood? And finally, why is egg layer so thick? [/INST] Hi. I can understand your concerns. Revert back to an infertility specialist online for further follow up --> </s>