<s>[INST] I have been suffering with fibromyalgia and cfs for about eight years now. It started when I got Legionnaires disease which lasted six months instead of ten days. Over the course of time I have been using hydrocodone and Savella to control the pain. Unfortunately the pain continues to increase steadily and I find that what really relieved my pain several years ago is now inadequate to control it. I currently take 5-6 hydrocodone daily (which has been one of the few drugs to actually bring me relief) and 2 Savella, 1 in the morning and one in the evening. I do not want to go back up on the hydro [I used to take eight a day, but got down to three at one point.] Is there another drug that would have more of an impact on the pain, but wouldn t be as harmful as 8 hydro a day? [/INST] Hi, Medications that seem to have a good track record of success in patients with FM are Lyrica (pregabalin), Trokendi (Long acting Gabapentin), and Cymbalta (duloxetine), Savella is also indicated for FM and you are already on this medication. Therefore, if you are to be tried on any other medication make certain you your doctor is aware since taking MULTIPLE medications at the same time as the Savella could get you toxic side effects. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Dariush Saghafi, Neurologist </s>