<s>[INST] hi, my wife is experiencing unpredictable swelling of hands sometimes left and sometimes right. she also experience it with her genital. what is possible cause of this. prompt reply will be highly appreciated. this happens frequently. (twice to thrice a month) [/INST] Hello, It could be a vasculitis.Consult a physician and get evaluated. A detailed evaluation is required to find out the exact cause. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Shinas Hussain, General & Family Physician </s>