<s>[INST] Hello doctor how are youi am a PCOS patient and was on glyciphage and aldactone for like almost 2 years. now we consulted a fertility specialist who discontinued these medicines and gave me oosure plus twice a day and MCBM 69 once a dayhow wil it help in controlling my weight as well,> are these meds ok.? i am very concerned as this becomes like a vicious circle, weight , pcos, infertility, weight and so on..email : [/INST] Hello,Oosure plus and MCBM 69 medications are quite helpful in facilitating your conception chances. They have supportive role.However, you have to undergo other fertility test to rule out exact cause:1) Husband semen analysis test.2) Ovulation test- Serial follicular study in mid cycle to check proper ovulation.3) Tubal patency test- by HSG (hystero salpingography) or laparoscopy.4) Complete hormone assay including D-21 progesterone, thyroid profile, blood sugar & prolactin test.5) Test for cervical factor- Post Coital Test (PCT), Anti-sperm antibody (ASA) etc.For weight reduction, you have to undergo regular physical exercise by means of jim workout/ treadmill/ cycling/ ab exercise etc. Low carbohydrate diet and fresh vegetables/ fruits, Vitamin-E supplement are quite effective.Kindly, consult with your doctor for complete evaluation with above mentioned tests. Good luck. </s>