<s>[INST] I have had constant lower right abdominal pain for going on 2 years now. I have been to the ER twice, seen two GI specialist, been examined by 3 OB/GYNs, had 2 CT scans, a colonoscopy, and stool samples. No one an find anything. At one point, I did test positive for C-Diff, and while the associated diarrhea went away, the pain did not.At my last OB/GYN visit, she suggested switching my birth control. I did, but I have seen no improvement. I have noticed the last few months that the pain seems to be worse the week before my period.At this point, I have no idea what to do and feel incredibly frustrated. [/INST] Hi.Thanks for your query.Read and understood your problems.This is a very typical case in which the patient has visited the GI Specialists, Gynecologists, has CT, colonoscopy, stool samples, suspected C.Diff which got treated and now diarrhea.Your pain typically starts\/ gets worst a week before the periods.Hence the probable diagnosis is:-Endometriosis or Anything associated with PID,, the pain increases with the rising congestion secondary to hormonal changes just before the periods starting from a week before the periods. -IBS, Irritable Bowel Syndrome.I would advise you the following in consultation with a Surgical Gastroenterologist and / or Gynecologist for a preferably combined treatment :::-Diagnostic Laparascopy can help a lot in diagnosis as  I said. This will be diagnostic as well as therapeutic in some cases. -If everything is normal, get a treatment on the basis of IBS and you may be fine. </s>