<s>[INST] My Mother 81 years old, was given Invega 6mg in the hospital in January. She was admitted for a UTI and low sodium level of 124. they were not sure if this caused the psychotic behavior so they admitted her to the senior psych ward and put her on Invega... It made her like a zombie but at the same time gave her the shakes and made her anxious (couldn t sit still, etc). On February 18th, the psychiatrist took her completely off the invega but she still has the anxious sypmtoms... is this normal? How long does it take to get this out of her system. The Dr. said she should be feeling a little better by now... HELP!!! [/INST] Hello Welcome to Health Care Magic.We understand your concern.I am Dr Alok Sinha, MD Psychiatry, from India.I will try to help you.Hyponatremia is known to cause a delirious state in a person leading to poor orientation about person, place and time, difficulty in focusing and shifting attention at will and altered sleep wake cycle. The person suddenly starts behaving strange, may claim that other may harm him/her or plotting against him/her. He/she may also hear strange voices, at the same time others may deny hearing the same. The person appears confused and puzzled, seems to be talking nonsense and often may shout or weep without obvious reason.  In such situation it may be necessary to start a antipsychotic medicines for some time, as in your mother's case the doctor started Invega (Paliperidone) a well known antipsychotic medicine. If hyponatremia is corrected then these behavioural oddities get resolved spontaneously and the antipsychotic medicine may be stopped gradually. So, your doctors have rightly decided to stop antipsychotic medicine now.Sometimes antipsychotic drugs have their own side effects like tremors of hands and feet, rigidity of limbs, anxiety, inner restlessness, tendency to move always and inability to sit at a place (called "akathisia").  Apparently your mother suffered this adverse effect.  You may discuss these issues with her treating psychiatrist who may prescribe her few medicines like clonazepam and trihexyphenidyl for some days to relieve her symptoms.Hope this answers your question. I wish her all the best. </s>