<s>[INST] My wife has been having some problems with her HEART RATE jumping up to 135, 160 just lying down and she has sharp pains in her chest and some numnes in her face, we have taken her to the doctor and they can not find any evdience of a heart attack, but something is going on. also after these attacks she is week and shortness of breath. [/INST] Hello, Regarding your concern, I would explain that your wife's symptoms could be related to a panic disorder. Anyway, before coming to this conclusion, I would recommend performing some tests: - an ambulatory 24-48 hours ECG monitoring in order to examine her heart rhythm trends for a prolonged time and exclude possible cardiac arrhythmia - pulmonary function tests in order to exclude a lung disorder - thyroid hormone levels for thyroid gland dysfunction - blood electrolytes for possible imbalance. You should discuss with her doctor on the above tests. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Ilir Sharka, Cardiologist </s>