<s>[INST] Hi, I am a 24 year old man, having a rare burning feeling while urinating for last 7 years. The problem has grown with time. Last year in USG, ~100 mal PVR was found, the uroflowmetry was not good and in cystoscopy, the comment prostate grade I congested was made. Now I don t feel the intense burning feeling at the time of urination but a more often irritation is there, specially after the ejaculation (even in normal time). Recently in RUG the urethra is seen to be narrowed (in a small region under the prostate) and my doctor prescribed the following medicine to see the responce: Niftran 100 mg and Silodal (silodosin) 4 mg. Afetr taking them on the very first day, I noticed the semen become very much liquid during ejculation. Is it a severe side effect and will it continue?? Is there a great possibility of getting cured by these medication? What are the most common treatment to this? No infection was ever found in urine or semen. Thanks ... Rustam [/INST] Hello Dr Faisal here,I have read and understood your query, I will tell u that niftran and silodosin doesn't have any such side effect. semen keeps on changing its consistency depending on hydration status.semen is  initially well formed and liquefies with  passage of time(liquefaction time). these drugs will help you a little .Niftran is for infection and it has to be taken for 7 to 10 days. the other drug(silodal) is a urethral dilator and it will help you in a long run.  if it doesn't settle and it is making a lot of trouble only then you should undergo dilatation maneuvers surgically . but i will suggest you that if u can take it along, don't worry much about this problem.  Hope I have answered your query. Let me know if I can assist you further.Take CareRegards.Dr. FAISAL BACHA, MEDICAL SPECIALIST (FCPS INTERNAL MEDICINE) </s>