<s>[INST] I have been on DIABEETE FREE program for9 weeks what heart medicines Can I elemate.Lost 28 lbs sugar has dropped from 200s to 120.Taking heart meds.metoprolo 50mg simvastatin40mg.enalapril 10mg clopidogrel75mg.isosorbide30mg.terazosin2mg. clopidogrel75mg. metformin 1000 a day reduced to 500. [/INST] Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Simvastatin is heart protective. DO NOT STOP IT. Good sugar control don't mean you can change hypertension drugs. If blood pressure is well controlled, can start reducing doses by a GP. Hope I have answered your query. Let me know if I can assist you further. </s>