<s>[INST] My father is detected with CKD5 in 2010 his Creatinine was 20 which was reduced to 4.4 through dialysis . In 2012 his creatinine level is same but his body weight is reducing day by day in 1 year he has reduced from 54 to 47 kg. Apart from CKD5 hes having below complications too: Aneamia (he s anaemic from day 1 and his Hb is always around 5.5-8, nowdays its just 5) Piles Hepatitis B Insomnia He has become very weak and irritated (he hardly moves out home, es retired and at home, although he do his daily routine normally) Please suggest what is the cause of his reduced body weight and what diet/medicines he should be given to regain weight, energy ,hb and his normal lifestyle [/INST] Hi Welcome to HCM and thanks for your query. Most of the complications mentioned are directly or indirectly related to the CKD. The anemia can be improved by erythropoietin and iron supplements. Apart form this he needs calcium and B Complex supplements and restriction of potassium intake. His diet will consist of low salt, moderate protein intake. His fluid intake needs to be adjusted after physical examination. It is a complex problem and should be managed in consultation with a nephrologist. Wishing him best possible health Regards DR GS </s>