<s>[INST] I am looking for a solution for extreme pain in all my joints. I was tested for RA and it came back negative even though my sister has progressive RA. My finger joints are large in the knuckles and my right knuckle is deformed and painful, finger joints are very tender to bumps and I have trouble picking up heavy pots and pans and opening jars. I am experiencing severe pain in my right side- hip and shoulder. So painful that I can t do my normal household chores. I m wondering if this is chronic inflammation and I have a severe sensitivity to drugs. I don t want to go that route. I am taking Melexacam for pain but it gives me bad discomfort in my gut. What do you suggest? What can I do? [/INST] hi tour symptoms do point towards rheumatoid arthritis even though your test is negative-- this is called sero negative arthritis. YOu should undergo complete check up and start medication early ,since it can be a disabling disease. </s>