<s>[INST] my wife has a serious infection in her leg which is eating through her skin we have already been to see our gp and she said that the infection is too serious for plastic surgeons to cut it out and cover with a skin graph and she said it might need to be amputated is there any other way [/INST] Hi,This type of severe infection is common in diabetecs so first rule out diabetes.If she is diabetec then consult diabetes leg specialist and get examined.There are all  chances of having gangrene on the part and amputation might require if not properly treated in time.Consult surgeon or diabetec leg specialist for examination and line of treatment.Ok and take care. </s>