<s>[INST] is there any side effect of par it D? i have been discovered irritable bowel syndrome (IBS). and also a bit of PID (pelvic inflammatory disease). have been prescribed mikacin 500mg injection twice a day and morease with par it D empty stomach. also mirtaz (anti depression) twice a day. are there any side effect or mikacin and mirtaz ? [/INST] Hello,Mitraz long-term use may cause anxiety, palpitations,dry mouth, tremor and irritability. Amikacine may cause fluid retention, nephro and ototoxicity.Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Penchila Prasad Kandikattu, Internal Medicine Specialist </s>