<s>[INST] I have had several surgeries on my foot due to an auto accident injury 2014. My concern is I am having severe pain in my right leg. Charlie horse type cramping that starts in the outer ankle, pain moving up the outer calf and down into the anterior part of the coco the making toes curl under. The knee pain is more often than not, a sharp And stabbing pain throughout then knee. With pain also in the upper thigh region. Note that I do have pins screws and grafting in the foot and ankle. Any ideas or suggestions? [/INST] Hello, It might be due to peripheral vascular disease arising due to the poor blood supply to the legs. As a first line management, you can take analgesics like paracetamol or aceclofenac for pain relief. If symptoms persist better to consult a general surgeon and plan for an ultrasound Doppler. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Shinas Hussain, General & Family Physician </s>