<s>[INST] I developed c-diff after hospitalization.  Now I have it again after taking amoxicillin for a sinus and bronchitis infection.  Will I ever be able to get shed of this stuff or is it something I will deal with every time I take antibiotics?  Is there a vaccine for it? [/INST] HelloI understand your concernI need to ask you certain questions first.What treatment you took previously for c.diificle infection?What exactly are the symptoms you are experiencing now?C.diificle infection are generally treated by drug metronidazole for 7-10 days if diarrhea is associated with fever and abdominal pain.If it is just diarrhea,it may be a mild infection,it will resolve  by discontinuing antibiotics which you are already taking for other health ailment.Probiotics can be used to aid regrowth of normal intestinal flora.If symptoms persists beyond 2days after stopping antibiotics,then a course of metro is given as mentioned above.If you have already done with this course and here is recurrence with diarrhea,fever,abdominal pain,a second line treatment with vancomycin drug is done for 7-10 days under prescription.Instead of amoxycillin,other alternative alternatives like erythromycin or doxycycline can be used if antibiotic treatment is neccesary for your sinusitis.Met your physician in this regard.Hope this information helps.Wish you good health </s>