<s>[INST] i went to er today cause i woke up fine and in the mid afternoon my thumb and part of my palm became very bruised hurted and i had numbness and tingling they ran various test and sent me home they could not figure it out i am trying to research online what it can be they did xray of the hand [/INST] Hello, It would explain that your symptoms could be related to local inflammation. A pinched nerve can not be excluded either. For this reason, I would recommend performing nerve conduction studies and inflammation tests (PCR, ESR, complete blood count). Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Ilir Sharka, Cardiologist </s>