<s>[INST] Hi, I am currently doing research about the Nipah Virus. I would like to know if there are any drugs or vaccines that have been tested on humans and if they are effective or not. What are the aspects of the Nipah Virus that still remain vague? What are some future studies that will be conducted in hopes of finding a vaccine to combat the Nipah Virus? [/INST] HelloThe following reading is taken as such Gantz's infectious disease latest edition 2013 .Nipah viruses were responsible for outbreak of several febrile "ENCEPHALITIS" IN HUMANS in MALAYSIA in 1999.-The outbreak was associated with respiratory illness in pigs and was initially considered to be JUVENILE ENCEPHALITIS because of epidemiology.-Other outbreaks occurred in Bangladesh & INDIA.The N genes of NIPAH virus have 78 % nucleotide homology ,but this virus has no more than 49 % similarity with any other members of the PARAMYXOVIRINAE.Now about the clinic finding :The incubation period for NIPAH virus ranges from 4 to 18 days .The onset of disease may be influenza-like with high fever & myalgia.Sore throat , dizziness & drowsiness and disorientation can occur.Mortality is about 50%.Nipah viruses grow well in Vero cells.- A cytopathic effects usually develops within 3 days in most cases.-Required a level 4 lab.-Positive virus neutralization tests, only in a level 4 lab, are demonstrated by the inhibition of cytopathic  effect producing by sera.---ELISA tests are less effective.-PCR available.The infection can be spread by the AEROSOL route, so care should be exercised as NIPAH  VIRUS has been isolated  in the respiratory secretions and urine of patients identified as having NIpah virus encephalitis in MALAYSIA & BANGLADESH.NO VACCINES or TREATMENT are available till 2013 .Future studies are continuous or not I DON'T KNOW.Hope this will be helpful for you. </s>