<s>[INST] My 4 yr old son, has history of GERD diesase, hole in the heart, hydrocele, hernia, night time leg pain. He recently sdtarted to have nighttime nose bleeds and a blood test revealed a slightly raised AST level. Are these related and should i be worried? [/INST] AST is a non specific enzyme...may or may not be associated with underlying liver disease...but if he has nose bleeds then check his prothrombin time because prolonged PT due to liver disease causes bleeding...since your child does not have other features like jaundice, the nose bleeds may be isolated event....unrelated to AST ... </s>