<s>[INST] My granddaughter has low white blood cells. She is mixed Afra-american and white. She is tired alot and is not real active. Short times. She went to the dermatologist because she had blogges and she ran a biobsy then ran the blood test that showed her white blood cell count was off. Any thoughts on what this could be? [/INST] Hi      Thanks for using Health Care Magic Forum,Low white cell count may be due to acute viral infections, such as with a cold or influenza. It can be associated with chemotherapy, radiation therapy, myelofibrosis and aplastic anemia (failure of white cell, red cell & platelet production). HIV and AIDS are also a threat to white cells.Other causes of low white blood cell count include systemic lupus erythematosus, Hodgkin's lymphoma, some types of cancer, typhoid, malaria, tuberculosis, dengue, rickettsial infections, enlargement of the spleen, folate deficiencies, psittacosis and sepsis. Many other causes exist, such as deficiency in certain minerals, such as copper and zinc.Drug for seizure can reduce WBC count in blood.I Hope I Provided Useful Information. Do ask Furthur Questions to help You get well soon.RegardsDr.J.Kingson John David </s>