<s>[INST] i have a herniated l4/5 disc with sciatic nerve pain.I have been on buprenorphine for past drug use (i dont use at all now or for past 10 years) so i want to change over to a painkiller for severe days however not sure which would be best. My doctor at the hospital who prescribes the bup suggested Jurnista however it seems not many chemists stock these so i wondered if you have any advice for me.My goal is to only take pills when in extreme pain to be most effective but i get the feeling a lot of the suggested pills one needs to take daily. Im a 57 year old female and wonder if any opiate has better health outcomes than others for the body. [/INST] Hi,Thank you for posting your query.Herniated lumbar disc results in radiculopathy, which causes neuropathic pain.Best medications for relieving neuropathic pain are pregabalin, gabapentin and duloxetine. However, I must tell you that these also need to be taken daily.Morphine is not a good option for long term use in your case.Please get back if you require any additional information.Best wishes,Dr Sudhir Kumar MD (Internal Medicine), DM (Neurology)Senior Consultant NeurologistApollo Hospitals, Hyderabad,My personal URL on this website:   My email: drsudhirkumar@yahoo.comMy blog: </s>