<s>[INST] I had a kidney transplant almost fours years ago. I was always a healthy person but they were just failing. I am female 5ft 10.5 inc and weight about 162 lbs. The last couple of months when I go to bed within ten minutes my legs get uncomfortable with the sensation of cold water running though my veins. What do you think it is? [/INST] it seems to me as restless leg syndrome,you should rule out anaemia,iron deficiency,vitamin dediciency,check thyroid status,check drugs like ranitidine,amitriptyline causes this </s>