<s>[INST] Hi, My bday party is Saturday, 11/6/10; however, 11/3/10, I had a severe allergic reaction to nuts. I was given steroids, pepcid and benadryl at hospital. I was sent home with 40 mg of prednisone 2x a day or 4 days, 40 mg of pepcid 2 x a day and benadryl 25 - 50mg every 4 - 6 hours. I went to allergist who gave me a script to ween off prednisone. For 11/5/10 - 30mg, 11/6/10 - 20mg, 11/7/10 - 10mg, 11/8/10 - 5mg (end). My question, the "caution category" on the prescription info sheet doesn't indicate if I could consume a glass (or two) of wine on 11/6/10; is it safe to consume 1 or 2 glasses of wine on 11/6/10? [/INST] HI, thanks for using healthcare magicThe alcohol should not be used if you are still currently using the medication.The benadryl would have sedative effect and this would be worse with the use of alcohol.In addition, alcohol can affect the stomach to cause gastritis which can also occur with the steroids.When the medication has been discontinued, then you can use alcohol.I hope this helps </s>