<s>[INST] I am taking omnacorticol 45 mg for last one month due to vasculitis problem in my toe tip. I have to take this medicine in a reducing dose (5 mg reduction each week) upto 8 more weeks. Is there any problem in getting pregnant wile taking this medicine? Also after 8 weeks if i continue to take 5 mg daily, is there any problem in getting pregnant [/INST] Hello mam, Omnacortil (prednisolone) is known to associated rarely with increased risk of cleft lip/palate in some studies.A risk of premature delivery is also possible.. Its better to avoid it during atleast the first 3-4 months of pregnancy when organogenesis occurs.. Now its better that you use some form of contraception till your tapering is over.. Take care </s>