<s>[INST] Hello doctor, I was suffering from OCD for four years. I had taken medication Fluoxetine and Clomipramine for it. I had recently started smoking one year back and now want to quit. I just want to know that does smoking further harm OCD. [/INST] Hello. Smoking can affect your OCD (obsessive-compulsive disorder). First, it can exacerbate the associated anxiety thus worsening OC symptoms. Second, it can affect the blood levels of medicines you are taking for treatment thus affecting their efficacy. The other harms of smoking are well known. So I would suggest you quit smoking. </s>