<s>[INST] I am currently undergoing acne treatment , with 2 and a half months into my Oratane course of 40mg, with another one a half months to go. While the acne has almost entirely disappeared, I am left with redness on my cheeks and neck as well spots (reddish too), also my skin tone has gotten at least 2 shades darker. My pharmacist suggested Demalin. How safe is it on dark skin? And in how long can I expect to see changes? [/INST] Hi, you are having redness over your face as you are on isotretinoin oral therapy and redness is a known and acceptable side effect with isotretinoin. You can use a mild moisturiser or calamine lotion to soothe your skin. However if your skin is dry or too much itchy along with redness then you might use a mild steroid cream or pimecrolimus. I would not suggest using demelan at this point of time as it would irritate your skin  and make it more red. Use a good sunscreen too, it will prevent darkening of your skin. Take care </s>