<s>[INST] Hi, I am 12 weeks pregnant. I was prescribed Clarithromycin 500mg at 11 weeks. I took it for 3 days (5 tablets in all) before my midwife strongly advised me to stop taking it. What risk has my baby had as a result of taking this?I had taken Amoxicillin 500mg for 3 days before this but it had no effect on a severe sinus infection, hence my doctor changed over to the Clarithromycin. [/INST] Hello, and I hope I can help you today. Clarithromycin is in a class of antibiotics that can be used during pregnancy, however the risks of taking it are less known than a penicillin-based antibiotic like Amoxicillin. However, there is no evidence that Clarithromycin is harmful during pregnancy, so you do not need to worry about the doses you already have taken. If your infection has not cleared from Amoxicillin alone, I suggest you either finish the Clarithromycin or consult with your physician about an alternate choice for an antibiotic.I hope I was able to adequately answer your question today, and that this information was helpful. Best wishes for the pregnancy,Dr. Brown </s>