<s>[INST] Hello Dear doctor, Hope you are fine. I am a women and I am 38Y. It is 16 months that I live with my husband and I have two small myomas which are not attached with endometer ( I did diagnostic hysteroscopy). My husband has oligo spermia. I did ICSI in July 2011but the result was negative.  The doctor told me to do it again. What is your advice in this regard. I am also a medical person.  Regards, Rahila [/INST] Hi,Welcome to HealthcareMagic .I would suggest you to go for ICSI as to be frank that is the only left option. Because your husband has oligospermia so chances of getting healthy sperm is by ICSI.  In this they will culture immature spermatozoa to sperms. If by ICSI sperms couldn't be grown then next plan would be donor sperm  hope I have been helpful .RegardsDr.Deepika Patil </s>