<s>[INST] My mom is taking Glipizide and Metformin.  She is having really painful side effects which make her veins in her legs hurt so much she has trouble walking.  They were not controlling her blood sugar levels either; she got to 500.  I started giving her Humulin N, 15 ml day and night.  This morning she finally got to 147 on her blood sugar reading.  Her doctor has finally started her on Lantus 15 mg one time at night..  My mom wants to stop taking the other medications because of the terrible side effects, will she be able to do this and be able to take the Lantus alone?  She is 71, weighs 185 and is 5 ft tall.  Has high blood pressure and lipidemia. [/INST] Hello, Thanks for the query to H.C.M. Forum. Weight 185  lbs, height 5' , age 71 years , diabetic , lipidemia , All are sufficient to develops pain in calf muscles( leg cramps). Since , how many days , she is having diabetes, mention it . Blood pressure is high ? lower or upper ( systolic or diastolic). In my opinion oral hypoglycemic with parental hypoglycemic will act together. Consult a Diabetologist and get his opinion. Hope I have answered your question. If further any question I will help. Good luck. Dr. HET </s>