<s>[INST] hi i am 27 years old.i have pcos.i want 2 be pregnency last 5 month.but i have no pregnecy.i take  metformin,bromocriptin,Mythyildopa,Alductone.i have high bp.my weight 82 kg. How can i reduce pco,prolectine,testosterone level?how can i pregnent.pls help me. Jisia bangladesh [/INST] Hello, Jisia.I am Dr Adil. Polycystic ovarian syndrome is not uncommon. My 3 female-relatives also have this disease. And i see many who visit gynecological clinic due to the similar problem.Yes, it is difficult to conceive with polycystic ovaries. This is because, polycystic ovaries often fail to release the egg, that is required for conception. Being over-weight is one of the risk factor. The aim of the treatment is, 1. Cycle regulation, 2. Treatment of the hormonal imbalance3. and the most important one, induction of ovulation (release of egg from ovary). You are taking the right treatment, metformin helps to lose weight and it also helps in the induction. You may discuss with your doctor about the addition of other medicines that help in ovulation induction. and i think one or more drugs that can be considered are missing from your list. There are other medicines also...! You may discuss it with your doctor, or you may change your doctor and visit someone who is well  qualified in the gynecological field. I am restraining myself from prescribing any medicine without proper history and evaluation. and don't worry, keep your hopes up, my all three relatives did conceive, although they conceived late, that is 3-4 years after marriage, with the help of treatment..I hope my answer will help you.Kind Regards.Dr Adil Ramzan </s>