<s>[INST] My husband is a very moody person.  One day he is fine and enjoys doing things with me and our kids and the very next day is can be VERY moody--will not speak to us at all and is very irritable.  It seems like this happens every month right before I am about to start. It seems as though it gets worse the older he gets! Is there any kind of medication that he can get from the doctor for this? [/INST] Hello,The symptoms are indicative of a possibility of mood disorder: bipolar? but to pin point the diagnosis one has to interview him in detail to know the reason of his up and down behaviour.You may better take him to a psyciatrist and Im very hopeful that after drugs are started he will feel much relaxed and your family will be at peace and will enjoy life in a better way.Usually, we use a mod stabilizing agents like sodium valporare or lithium or oxcarbazepine in suh cases depending on several other actors- like presnece of hypertension or diabetes or some other comorbid illness.Also you must get his baseline blood tests like TSH, lipid, liver and kidney, blood counts,  ECG test before proceeding for any medicine.Wish you good healthDr. Manisha GopalMD Neuropsychiatry </s>