<s>[INST] Hello doctor,I had been diagnosed as a person with diabetes before 10 years. Now I am taking Amaryl MV 2 bd dosage. Still, my rbs is around 250 to 270. What I need to do? Is there any possibility that I can avoid insulin therapy and by oral therapy only I can be treated? And now I think I am facing problems with neuropathy also. Pain in the palm and numbness in the feet even some sexual issues also. Please suggest to me what kind of treatment I should follow. [/INST] Hello. You are facing complications of diabetes, to control sugar you can take Glimipride 3 mg before breakfast and Sitagliptin Metformin 50/500 mg twice daily after breakfast and dinner. Avoid junk food, fatty meals, and deep-fried items along with sugary drinks. Brisk walk for 25 minutes for five days a week. Avoid anxieties try to relax. Eat Short meals instead of three meals, I mean divide your daily meal into small portions. Complications due to uncontrolled diabetes. 1. HbA1c,  2. Lipid profile. 3. Serum creatinine. 4. Urine analysis. 5. Fasting blood sugar. </s>