<s>[INST] For several years I have had peripheral neuropathy, drug induced (nitrofurantoin), but a symptom other than the tingling and burning suddenly occurred this morning ... very heavy legs. Are they connected? Or are the heavy legs due to something else? [/INST] Hi,heaviness of legs is due to  some other cause not due to peripheral neuropathy.It may be due to lumvar spine pathology or brain involvement .Before advising investigation I  would exam you .You are advised to consult neurologist.Thanks </s>