<s>[INST] I am having a creatinine level of 2.6 however my urea is within normal range.I take medicines for cholesterol -tonac tg,Diabetes-Novoronn and glimy,Anti coagulation-Preva As,Admenta,And anti depressant-Citopam 10.Also For pressure I Take Losar-25.Can you tell me the reason for this rise in creatinine level and it is continuosly rising last time it was 2.1 and now 2.6 [/INST] Hi There are quite a few underlying diseases and several drugs involved here. Nevertheless, your question may not have anything to with them!? Generally both urea and creatinine rise together (eg. renal impairment) At times urea rises disproportionately (eg. Dehydration). Raising creatinine with normal urea is rather unusual - It could mean technical error - repeat it If it is still the same, one need to investigate for metabolic / muscle disease Good luck </s>