<s>[INST] Hello doctor, I had this acne situation for the past three months. I am not sure of the cause. It started from the side jawline till the cheeks, and it got worse. I tried Benzoyl peroxide and it only helps to control but does not get well, and the skin got dried. Is it a hormonal change? What can I do? I am depressed for a year. Kindly advice. [/INST] Hello. Acne along the jawline and lower face can indeed be an indicator of hormonal imbalance. Do you have any menstrual irregularities, or facial hair growth or recent weight gain? I would appreciate if you send me the photograph to assess the severity and nature of your acne. Use the following medications after consulting your treating doctor. 1. Tablet Azithromycin 500 mg three days per week, for three consecutive days. 2. Use Adapalene plus Clindamycin gel. Apply once at night on acne in little amount without rubbing it and wash after one hour. 3. Use Benzoyl peroxide face wash. Do this for three weeks. </s>