<s>[INST] sir am 22 yrd old, and i hav got tan on my forehead, chin,also there are dark patches encircling my eyes due to specs .m using clearxmax(hydroquinone,tretinoin,fluocinolone acetonide),hav noticed bit of changes bt red patches are cuming along with bit of burning sesation..is ti abnormal?? [/INST] Hi, If burning sensation is marked cream may be stopped and follow up with prescribing doctor or a dermatologist should be done. Tretinoid and Acetonide may cause these side effects. Meanwhile OTC analgesics like acetaminophen can be used for anti inflammatory response or pain suppressants unless the lesion s reviewed again. Hope I have answered your question. Let me know if I can assist you further. Wishing you a speedy recovery. Regards, Dr. Saddiq Ulabidin, General & Family Physician </s>