<s>[INST] Yes, I was on antibiotic for a bad skin infection and the I was given a Z pack for a sinus infection. Took Diafluciane for yeast infection. But not all of the rash went away. I am 67years old. The rash is in my anal area. What could this be and what should I take ? My name is carol [/INST] Hello Carol,Thanks for posting here your question.From what you are describing, it looks like it is a yeast infection caused by the antibiotic. The fact that Diflucan worked, even if just partially, confirms that. Sometimes using just one dose of Diflucan is not enough for yeast infections of the skin. If I was your caring doctor, I would recommend using for some days a topical cream like Fluconazole cream, ketoconazole 2% or miconazole 1%. The topical antifungal will avoid systemic side effects and clear the area that has still the fungus.Hope this helps,Take care.Dr. Papaqako </s>