<s>[INST] my brother is 40 years old, blind, mentally retarded. in the last 6 months has been a major behavioral change wants to eat in bed, gets suddenly aggressive,angry,  does not want to shower, lost weight, does not want to be around people . he can not communicate , he lives in Israel. how can we find out what is wrong with him [/INST] DearWe understand your concernsI went through your details. I can understand. Mentally retarded and blind. I am sure that he is under treatment. The best way to understand his present status and diagnosis, is to consult the same doctor who treats him. Online diagnosis of the case with given description is quite difficult. Take care.If you require more of my help in this aspect, please use this URL.  Make sure that you include every minute details possible. Hope this answers your query. Available for further clarifications.Good luck. </s>