<s>[INST] Dear sir, my wife has been diagnosed with gall bladder stones . The US report says Gall bladder appears contracted and shows few small calculi in its lumen... Gall bladder walls are of normal thickness. No Pericholecystic collection seen. The Liver function test says: S: Amylase ---- 1502 U/L SGOT (AST)-----592 IU/L SGPT (ALT).-----421IU/L Bilirubin -----------0.9 Mg/dl Alkaline Phosphatase : 169 U/L She got acute pain in upper abdomen before 5 days followed next day we did all these tests. Kindly suggest the best Advice please. We are from Delhi. Regards Deepak - 0000 [/INST] Hi Deepak Thanks for writing in. The serum amylase report is very high. This suggests an acute pancreatitis which can explain the pain she had. Sometimes the stones in the gall bladder pass down to the pancreatic duct and obstruct it causing pancreatitis. Also the SGPT and SGOT are very high. I would suggest you get her admitted with some Gastroenterologist  ASAP.  A symptomatic gall stones  requires a surgery. I would also be happy to review the tests reports , so please send me over all the tests reports in detail. Hope I have answered your query. If you have any further questions I will be happy to help Regards Dr. Om Lakhani </s>