<s>[INST] my mother has red lines similar to streaking all over upper and lower right leg. she does not have any problems with them being itchy or painful what so ever. she has been complaining of joint discomfort that is worse when she firsts wakes however no pan in chest/increase with touch. I am not quite sure what it could be i see no sign of infection? [/INST] Hello,I would explain that her symptoms could be related to Cushing disease. For this reason, I recommend checking cortisol plasma levels and some other blood lab tests (ACTH, complete blood count, thyroid hormone levels, PCR, ESR). You should discuss with your doctor on the above tests.Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Ilir Sharka, Cardiologist </s>