<s>[INST] my daughter is around 9 yrs old she suffering from epilepsy first attack came on feb 2007 & second was on 17 sept 2011 after 3.5 yrs. both attck came in deep sleep.her all report like Video eeg ,Mri ,Ct Scan ,EEG are normal. now she is on valparin 300 mg crono twice daily,she suffering from hair loss & weight gain problems. pls advice me [/INST] Hi, Thanks for writing in. Valproate is know to cause the side effects that your daughter is experiencing. even though it is expected to get better over time, if the weight gain is significant (>2 kg/month), we should consider other drugs as well. If she has absence seizures, the other drug can be ethosuximide or lamotrigine . If she has GTCS, she can be given phenytoin, carbamazepine or lamotrigine. Please speak with her neurologist about this. Regards </s>