<s>[INST] just two months shy of 45. Started having pitting edema in feet. have pcos and weigh 275. fatigue easily. hip and knee aches occasionally. Seem to have gained about 15 pnds pretty fast. will losing weight help with edema and how many pounds before it helps [/INST] Hello, The pain in the knee and hip are the cause of gaining weight. Losing weight won't reduce the edema instantly. Pitting edema is a sign of lack of venous return. You need to exercise for the knee and hip to strengthen and the muscles of the thigh and legs so the swelling reduces. If more needed instantly then lasix will be the drug a physician can help with. It's a diuretic and will lose the volume of fluid from the body through kidneys. But I will advise doing exercise in combination with the medicine or else the edema will come back. Hope I have answered your query. Let me know if I can assist you further. Regards, Jay Indravadan Patel, Physical Therapist or Physiotherapist </s>