<s>[INST] My lip randomly swells, no pain, just a tingly feeling, what is wrong with me? For the past 2 weeks my lip randomly swells up. It does not always swell in the same area, sometimes my upper right lip, other times my lower left, ect. I do not believe it is an allergy because the swelling is not consistent with any particular activity. What I mean by that is, my lip sometimes swells during work, or when I am sleeping, or even in the middle of class. Benadryl has no effect. The swelling varies in duration, from an hour to a whole day. I feel no pain, just a tingly feeling when the lip is starting to swell. I can also tell when the swelling is going to start. I am a 19 year old male, healthy, no history of allergy. I also only have one sexual partner that i have been with for over 2 years, so I am ruling out an STD. [/INST] Hi, This seems to be due to allergic problem (even though you feel it is not because of allergy). Try taking Vitamins and Antihistaminics (such as Cetrizine/levocetrizine), drink plenty of water. Any more doubts you are welcome. Regards Dr. Naveen Kumar </s>