<s>[INST] Hello Doc. Samuel here. I've a brother who was beaten by a dog over three weeks ago but nobody knew except him. Now, he's extremely sick and in dire condition. He gets so irritated when he sees water or is invited to drink. Doctors said that it is clearly "Hydrophobia" (Rabies) and nothing to do as it's long over due. Is there anything that can be done to cure? Any hope for him to get well? What will be his next fate? [/INST] Hello  Unprovoked infected dog bite is dangerous and if no precautionary measures and immunization is taken then it may lead to development of Rabies and consequent hydrophobia. Diagnosis in most cases is made on the basis of clinical history along with history of dog bite. Its very sad to say but so far there is no cure of Rabies Hydrophobia. Best you can do is prey and provide him symptomatic treatment. Recently in United States a study was done on mice and it was found that ketamine (anesthetic medicine) has potential to inhibit virus. This result in introduction of induced coma in treatment of Rabies and so far 2 patients have been saved by this treatment. The treatment is named as Milwaukee Protocol. Hope it helps you. Thanks Dr. Seikhoo Bishnoi, MD </s>