<s>[INST] My husband was diagnosed years ago with bah. His urinary problems have gotten worse. He is a 66 year old male. His psa was 5.1. His prostate has some calcification. He has no pelvic pain, weight loss, blood in urine just the basic bah symptoms. A TURP is being scheduled. Is this a high indicator for cancer. [/INST] Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Ability can be used by a patient who is already using Lamotrigine and Paroxetine provided there are valid indications. However it should be noted that the paroxetine have effect on metabolism of Lamotrigine and such combinations should be avoided as far as possible. Regarding your another part of question there is definite risk for prostate cancer but nothing suggestive of very high risk indicator. Hope I have answered your query. Let me know if I can assist you further. </s>