<s>[INST] hi my sister has atypical lipoma retroperotoneal left side excised twice now mri with contrast showed infiltration in l4l5 with backpain some doctors said it is terminal other want to operate and said that the mri report is wrong because atypical lipoma sclerotic type never infiltate locally in bone please help email catnottiger@yahoo.com many thanks [/INST] Hello. Thanks for writing to us. A lipoma if it is showing infilteration on MRI needs to be operated before it turns carcinogenic. Also the infilteration may increase and affect other vertebrae also and slowly the nerve compression symptoms might appear. I hope this information has been both informative and helpful for you. Regards, Dr. Rakhi Tayal drtayalrakhi@gmail.com </s>