<s>[INST] My husband, who is is on TRT and Arimidex, has been struggling to find the right doses of both. Since being on these medications, he has been having problems either getting or maintaining a firm erection. He has made several modifications to his med dosing and is using a penis pump as well. He is 51 years old and is healthy and fit. He does have mild HTN and takes a very low dose of Lisinopril. We have been married for 24 years and he has never had this issue until he began with hormone treatment. He is afraid to stop the treatment because of fear that it will take a long time for his body to make testosterone again. This issue has been going on for 2.5 years and we both are in distress over it. It is affecting our marriage. Please advise. [/INST] Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Arimidex dosage is 1 mg per day. He is on testosterone replacement therapy. Right now serum testosterone how much we don't know. Anti hypertensive drugs may also cause libido. Also get examined for other causes for Ed. Hypertension, hypothyroidism, anemia, stress, anxiety etc.. Until examination is done it is difficult to say what it is. Please consult your treating doctor he will examine and treat you accordingly. Hope I have answered your query. Let me know if I can assist you further. </s>