<s>[INST] My wife is 49, 5'2" and weighs about 140.  She had a stage 2 melenoma on her right thigh almost 2 years ago.  For three days now she has had what feels like a small round ball like irratation under the skin on the bottom of her right foot.  There does not seem to be a break in the skin, so we believe it must be a gland or lymph node or something?  It is painful to the touch and to walk on and she said it was itching some.  what do you think we should do, give it time or have it checked. [/INST] Hi,Thanks for writing in.Any patient who has malignant melanoma in the past must consult a doctor immediately if there is any lump, swelling, skin changes or any suspicious symptoms. Please get her examined by the oncologist at the earliest and get her condition confirmed.Malignant melanoma is one of the violent tumors and can spread to any where in the body without any particular signs or symptoms. Even if the area looks more like an inflammation and without break in the skin it should not be ignored. There are symptoms like irritation and itching which means some pathological process is taking place. Please do not worry. </s>