<s>[INST] Hi, my son is k/c/o Thalesseamia major. He has fever since Monday, it keeps on fluctuating 20 Oct 2014 his HB was 9.6, wbc 4600, platelets 181000 Fever ranges between 99 to 102° f 22 Oct HB 8.8, wbc 3000, platelets 136000 Dengue ns1 was negative Psmp negative Sgpt was 182 Yesterday full afternoon he was normal, no fever, but at night 102°f Today also 102°f I m scared for the following reasons 1 blood can t be transfused coz his fever is still there, how much will the HB drop from 8.8 on 22 Oct till today 2 he is feeling very sleepy 3 his motions are lose since last night, total 2 motions 4 has is wbc fallen more 5 has his platelets decreased further I have been giving him crocin D s 8ml and ibugesic 13 ml Please guide me and also guide me if I can transfuse blood in such condition [/INST] child having high grade fever, a case of Thalassemia, with deranged LFt(SGPT - 184), with loose stools with decreasing platelet count goes in favour of either Enteric fever or Viral hepatitis(could be transfusion induced). Dont transfuse blood at this point, the child might have to be admitted and might require antibiotic therapy. Take a pediatric consultation asap as the child might develop sepsis later on. </s>