<s>[INST] Hi I am 49 yrs, male. middle part of all the fingers (softer side) of my both hands including thumb have itching, flaking, cracking skin. Doctors say it is due to metallic / nickel allergy . soaps also react and worsen the problem. I have tried petroleum jelly, moisturizer and creams but not getting result. can you please guide me? [/INST] IT MIGHT BE FUNGAL AS NO MOITURISER WORKS ON ITI ADVISE TO ADD ANTIFUNGAL FLUCONAZOLE 150 MG ONCE A DAY FOR 4 WEEKTAKE FEXOFENADINE 120 MG BD ANND CAN ADD CPM TAB AT NIGHT IF MORE ITCHING AT NIGHTKEEP AREA DRY AND AIRY AND SWEAT FREENON OILY AND NON GREESY FOODSNEED TO CLEAN WATER AND MAKE IT DRY AFTER EVERY TIME WHEN YOU PUT WATER ON HANDSAPPLY ANTIFUNGAL POWDER AND CREAMS 3 - TIMES A DAYCONTINUE 3-4 WEEK </s>