<s>[INST] I have several lumps under the skin on my inner thigh, they burn and very painful to walk, and sleep threw out the night. I did have blood clots in the past, and I m worried, should I be, What should I do. I went to a doctor and was told its from vertical veins, but I received no answer on what to do. Please help? I also have a Factor 5 blood disorder, that I found out five years ago. [/INST] hello there! Thank you for asking.Factor 5 deficiency with the symptoms you presented are indicative of Esophageal varices with or with out associated DVT. So you need a good endovascular surgeon with allied hematologist to work up further. Clot plus vasculitis plus varices and DVTs need to be ruled out.take careS khan </s>