<s>[INST] Hi doctor, I am pregnant, and my entire body is itching. What could be the reason? Please help. [/INST] Hello. If there is itching alone (especially involving palms and soles) without any skin rashes, it could be a condition called obstetric cholestasis. In obstetric cholestasis, the liver is unable to send out the waste product called bile acids, and they accumulate in the blood and get deposited in the skin leading to itching. This can be picked up by a simple blood test. It can affect the baby if the levels are too high. We generally deliver the baby by 37 weeks to avoid this. You will need other tests to check for liver function, hepatitis virus, etc. And we need to monitor the baby through scans, CTG (cardiotocography), etc. </s>