<s>[INST] CONCERNS: I ve noticed that my legs have been swelling mostly around the ankles.....Both ankles. It s not that bad, when compared to previous swelling issues but it is the longest - since about February. I did start a new desk job so I am sitting more. But I started that back in November, and most days I walk during my breaks and for 20 minutes during lunch. What is concerning me more is that my calf muscles are getting really tight. And, I have a bump now on my right calf that has moved a little bit; around this area, there’s also a sensation like my muscle might spasm. Mostly while at my work desk, I notice my muscles tightening in my calf, hamstring and into my inner thigh. It s slightly worse on my right leg. HISTORY/ETC: I m a 37 year old female; about 60lbs overweight. I exercise lightly about 2 to 3 times per week; have a history of issues with my IT Band in my right leg tightening, and tailbone issues. Due to the tailbone issues, I m unable to sit ergonomically correct” in my desk chair and therefore sit at a recline. I am currently taking 50mg per day of Sertraline (started about 8 weeks ago). ETC: I ve tried drinking more water, stretching more, and elevating legs - and it doesn t make a bit of difference. Most physical activity hasn t really bothered it....maybe walking a little bit. Thank you for your time:) [/INST] Hello, As this appears to be a lack of venous return issue. I will advise you to modify your exercises and change it to aerobics 5 days a week. Sitting for longer in a wrong position can apply stress over the lumbar spine leading to paraspinal muscle spasm and the symptoms of calf muscles tightness. Changing the routine of the exercise and doing a frequent change of position will help to reduce the symptoms. Also using piles pillow will be good to avoid pressure stress applied over the tail bone and there by reducing the inflammation. Posture correction is a must. Hope I have answered your query. Let me know if I can assist you further. Regards, Jay Indravadan Patel, Physical Therapist or Physiotherapist </s>