<s>[INST] I have a close family member who is experiencing very serve medical issues. He was told that he has a hole in his brain. the doctors asked him if he had ever been shot or stabbed. No, he has not. They have him in the hospital for observation because the hole is eating away his brain and has moved to his face where it is now eating his cheekbones. They are going to do surgery in a few days on him. I am trying to find out some side effects for spice (fake weed). Could this be something that has cause his sudden illness? [/INST] symptoms described by u are suggestive of multiple myeloma. Get his MRI brain and serum electrophoresis for M protein done. regards. </s>