<s>[INST] Hi, I have been diagnosed two days ago with e coli that counts 10 on seventh, and got antibiotics Ciprobay 500 mg. But, I have constant low back pain which spreads to the legs. I can not sleep at all!! What I need to do in order to get better?? Thanks! [/INST] U r having back pain with radiculopathy along with uti most probably. I advise my pts for mri in such cases. U will get benifit by physiotherapy and back strengthning exercises. If it is severe and mri shows disc buldge etc u may require surgery. </s>