<s>[INST] Hello Doctor,pl.help me.I am  69,suffering from Osteourtharities on both of my knees for many years.and also gout on my lefl knee.Since last 6 mnts,I am feeling severe pain on my right knee,for which I can't walk properly,after standing from chair,I can't walk and have to wait for a while.So long I have takien pain killers like Zerodol sr, ACE-Proxyvon,Emanzen-D,etc.So long I am taking pain killer,I am feeling better.Now I have been pescribed Zerodol SP. Pl.advice me,which is the right medicine for me to det relief from my severe pain and how long I have to continue the pescribed medicine. [/INST] hitry to avoid painkillers as much as possible,it is not good for the kidneys & the liver in the long runyou can start with immunomodulating drugs like diacerin with glucosamine,vitamin d3 for osteoarthritisfor pain please try with pregablin or gabapentin which no sideeffects on the kidney under medical supervisiontake care </s>