<s>[INST] my uncle is having a calculus of 4mm in left lower ureter near uv junction and GR1 hydronephrosis and also a 5 mm calculus at mid pole.... he is having continuous pain from last 3 days the pain gets relieved on taking injections and medicines  but as soon as the effect is over it again occurs  what should be done in this case? [/INST] HI,I AM DR.TIWARI.FROM YOUR HISTORY IT APPEARS THAT YOUR UNCLE IS SUFFERING FROM NEPHROLITHIASIS THOUGH THESE TINY CALCULI WILL BE PASSED NATURALLY .IT MAY REQUIRE FLUID THERAPY TO EXPELL THEM OUT. GET HIM INVESTIGATED FOR METABOLIC DISORDERS CAUSING KIDNEY STONES. </s>