<s>[INST] I have Policystic Kidneys ( diagnosed in 1988) and to ensure that my BP is under control, I was prescribed Lorem 5mg and Amlogard 5mg, bds, initially by the Nephrologist . Later on, it was observed taht my BP is in teh range of 140/100, so the dosage was inreased as folows: Amolrad 10mg, Lorem 5 mg in morning and Amlogard 5mg, Lorem 5mg at night. I had been taking this dosage and my BP was normally 130/85-90 or at times it would be 140/90. About 2.5 months back, when i visited the nephrologist for regular check up, my BP was 150/100 and so my dosage was prescribed as Lorem5mg, same as before, Amlogard 20 mg in morning and 10 mg in evening. After few days of taking teh increased dose, I started observing swelling in my feet and increase in the girth of my legs. I was concerned and so again visited the doctor. He mentioned it could be due to Amlodipine and so he changed the medicine to S.Numlo 5mg, Arkamin 100mcg and Lorem 5mg-- BDS. However, since then, the swelling has almost gone in my left foot , but teh girteh of both legs is till in increased in size, I get lot of itching, at night. The portion, just above the ankle on both legas, is showing red patches- this stae when shared wth the Nephrologist, I have been advised to go for venous mapping, wich I am yet to get done. Please advise, even if S.Numlo has amlodipine, why Amlogard wsa stopped and why thsi swelling occured. Is t becaus eof Amlodipine or something else. Thanks red patchesnot reduced ( i generally go after ahve been taking [/INST] Please check your kidney function tests. Itching and red patches can also mean worsened kidney function. It can happen due to natural history of illness or due to recent increase in dose of Lorem. Amlogard/S-Amlo cause leg swelling in roughly 5% of patients and not all. </s>