<s>[INST] Hi, I am 62 years Male suffering with Parkinson disease, hyper tension, Anaemia and TB infection and recently diagonised with Rosai Dorfman Disease.I already had spleenectomy done 30 years back. Can I know the causes,symptoms and treatments available for RDD?Is it curable? I have been operated in the right axillary lymph node and 2 swollen structures were removed. what are precautionary measures i need to take and what about the chemotherapy, does it have any side effects? what is the diet i need to follow? Please email me at the earliest thanks, [/INST] Treatment depends upon the individual patient and is planned after thorough testing to determine the extent of disease. Ideal treatment, however, has not been established, and there is no ongoing clinical trial. It is believed that 70% to 80% of patients have spontaneous improvement of symptoms without treatment, although they may have alternating episodes of worsening and relieving of symptoms for a long period of time. Some patients with severe or persistent disease or cases where organ function is threatened (such as breathing obstruction or kidney failure) may require treatment with surgery, steroids, and/or chemotherapy. Rarely radiation therapy may be used. Chemotherapy may include vinblastine, 6-MP, methotrexate, thalidomide, or Gleevec. The ultimate goal of an overall treatment plan, of course, is to use as little treatmen </s>