<s>[INST] Hello doctor,I am a 27-year-old pregnant lady. I am in 31 st week of pregnancy. My WBC has been increasing off late. My present WBC count is 19.0×10^3 cells per liter. And I have not had any infections from the time I am pregnant. Now I have been asked to get an MPN panel test. It has got me worried. Now I would like to know the chances of MPN test results being normal? And I would also like to know if this happens to pregnant women where in the WBC increases during pregnancy and goes back to normal after delivery? [/INST] Hello, Welcome to the icliniq.com. The total WBC count can be elevated normally as well in pregnancy. It is a physiological response to pregnancy. The count can generally return after some time. If there is no sign of infection like sore throat, cold, burning micturition, diarrhea, etc., then you might not worry regarding that. However, kindly attach your CBC (complete blood count) report so that I can comment further. It is advisable to investigate with peripheral smear examination report first and then if needed MPN panel by flow cytometry suggested. So your chance of having MPN negativity can be predicted after looking your full CBC and peripheral smear examination report only. So kindly attach that two reports. I hope I have answered your question. </s>