<s>[INST] I look after a 47yr old man with profound retardation and is non verbal, his psychiatrist stopped Abilify almost 3wks ago due to it making him very restless. She prescribed 20mg Propranolol 3 days ago to stop the Abilify side effect and he still cannot sit in one place and keeps pacing back and forth. He also has a sprained ankle, but it cannot heal because he cannot not sit down for more than 2 minutes.....Is the Propranool dosage too low? Please Help!!!!! [/INST] hello,You may increase the dosage of propanolol to 40mg, in form of 20mg in morning and then in afternoon. If that dosent help- start trihexphenidyl 2mg in morning and 2mg in afternoon. I hope by taking this his akathesia ( irresistable moving of legs) will reduce and stop. This (akathesia) is a common side effect of abilify and may also reduce with time. Wish you good health.Dr. Manisha GopalMD Neuropsychiatry </s>