<s>[INST] i am 55 and suffer with ms I have a redundant bowel the muscle is completly dead but anal irrigation is working so far. I have had episodes of blood in the urine I have had lots of tests but they have found no reason. MY question is could the MS be damaging my kidney. I have paroxsmsmal spasms and take targin and oxynorm for pain as i had severe effects from all the neurological pain killers? [/INST] Hi,Thanks for writing in.Multiple sclerosis is condition affecting nerves and this can cause symptoms due to bladder disturbances. The symptoms can include all of those associated with both emptying and storage problems, and can also lead to kidney damage. Bladder storage dysfunction is a symptom of overactive bladder. This can cause your bladder muscles to contract more frequently with urges to urinate. There can also be an emptying dysfunction when the bladder does not empty completely. It’s possible to have both emptying and storage dysfunctions if you have multiple sclerosis.I suggest you get an ultrasound scan for your kidneys and bladder to know if there is any overfilling or obstruction in bladder. </s>