<s>[INST] My brother had first seizure 6 years back  after getting treatment for  Schizophrenia disease ,seizure repeat after 3 years ..he is prescribed epsolin er 300  and gardinal 60 +30 daily  by doctor ..how long he has to take the medicine ...  ......thanks [/INST] Hi,Regarding your concern, I would explain that this therapy may need to be taken for some years. You should know that antiepileptic drugs are usually prescribed for years, and are usually stopped gradually after 3 years seizure-free. Anyway both these drugs have a lot of adverse effects when taken for a prolonged times. There are a lot of treatment options, which have less adverse effects (carbamazepine, valproic acid, lamotrigine, etc.). You should discuss with his doctor on the above issues. Hope to have been helpful. Let me know if I can assist you further.Best wishes,Dr. Aida </s>