### instruction:
If you are a doctor, please answer the medical questions based on the patient's description.

### input:
My sister aged 42 years is under various medications prescribed by the Psychiatrist in the last 2 years.... With various medications, she feels better then and from July 2011, doctor prescribed medications of LONAZEP 0.25 (0-0-1) and OLEANZ PLUS (0-0-1) for one year... As of now (May 2012), in the last 10 months, though there was NO side-effects noticed, But, in the last 2 weeks or so, she is finding it difficult to concentrate much on routines, not showing interest in anything , feels sleepy always, change in food habits , tend to eat more sweets, etc.... I told the doctor last week, he told me to reduce LONAZEP 0.25 tab to 1/2 at night for a month and 1/4 tab to later one month and discontine from July........ Is there any side effects of the LONAZAP further.. We are based in India...

### output:

Hi and welcome to Chat Doctor. Thanks for your question... Clean Plus is a combination medication which contains Olanzapine 5 mg (which is given for psychosis) and Fluoxetine 20 mg (which is given for depression). Located is a medication given for sleep disturbance and anxiety. Though you have not mentioned the initial diagnosis made at the time of starting the medication, I am presuming that she must have suffered from depressive and psychotic symptoms, which must have been the reason she was put on that particular combination.  Now, you have mentioned that there were no side effects noticed so far with this medication. It is therefore very unlikely that she is suddenly having side effects of Located after being on that medication for about 10 months. Moreover, 0.25 mg is a minimal dose and is unlikely to suddenly cause all these symptoms.  The symptoms which she is experiencing, i.e. difficulty in concentrating, lack of interest, lethargy, excessive sleep, increased appetite, etc. may be depressive symptoms. I would suspect that she may be having a relapse of her depression. I think you should discuss this with your doctor, so that he can assess her in detail to see if she is actually having a relapse of her previous symptoms.  Furthermore, I think it is okay to taper down the dose of Located, because sedative medication are usually advised only for short periods and can have an addictive potential. Nevertheless, I strongly feel that she needs detailed assessment and further observation in order to be given the correct treatment. All the best. - 