### instruction:
If you are a doctor, please answer the medical questions based on the patient's description.

### input:
Hello, I am 57 year old female and have psoriasis (severe) since 1992 & Hep. B&C. In 2012 I took a year of my life and did the Ribavarin/Intefuron treatment and was Negative the entire time, however 2 weeks after completing treatment I RELAPSED. Anything I do for psoriasis effects my liver & vice versa. I have during this time been on every medicine available from creams, lotions, shampoos, injections etc., I am at a stand still right now plus I have arthritis in every joint. For the first time since 1992, the psoriasis seems to be in a Remission, not totally so I guess I cannot say Remission but it isn t covering my back at this time and I am so happy for this, I would like to know if you can inform me of any New Medications if available for my problem with my liver/psoriasis that I can TRY without it making the other out of control? Thanking you in advance Karen YYYY@YYYY

### output:

Hello, I can understand your concern for Psoriasis with liver problems. After analyzing your query I can make out that you have psoriasis since a long period of time. In general, we prefer to give methotrexate in psoriasis patients but as you have liver problem, so I would not suggest taking the same. In your kind of condition I generally start with Vitamin D3 tablet on daily or weekly basis. Additionally, I prefer to give a steroid based cream such as clobetasol or mometasone. An antihistamine tablet like cetirizine is preferred to relieve the itching. I also suggest doing miniaturization of the area. All the best.