### instruction:
If you are a doctor, please answer the medical questions based on the patient's description.

### input:
Is there a clear difference between Histoplasmosis and Miliary TB.  My tests so far indicate that at sometime I was exposed to Histo.  But after lung wedge biopsy everything keeps on coming up negative ( but show I have the granulomas all over both my lungs).  Plum. Dr. thinks we should try Itraconazole, Infectious Diseases is not sure and leaning towards TB.

### output:

Hi Dear !! Thanks for your query to Chat Doctor. Read and reviewed your query and health concerns. IN the given situation of Yours, You seem to suffer from-Histoplasmosis-which has micronodular lung pattern, and can mimic Military TB. But immunocompromised body state in HIV patients, both could be present simultaneously. Antigen testing in urine and serum is more sensitive (80%) in diagnosis of Histoplasmosis. Other causes-like Acidosis/blastomycosis need to be ruled out with Chest Physician Consults and CT chest and flexible bronchoscopy. This plan would reduce your dilemma from histoplasmosis and Military TB. Hope this would help you to plan further of this complex illness of yours. If need be, update any health issue 24 x 7 by a direct question Tod ME, at following Chat Doctor link-Dear, if satisfied, Dont forget to close this query with YOUR pleasing feedback comments to rate this reply and service, to boost the morale of incoming Emergency patients like YOU, at Chat Doctor services. If you want to update more details and ask more update queries, You are most Welcome herewith !! Good Day!! Wishing Good Healthy Life in time to come!! Chat Doctor. N. Senior Surgical Specialist. S. Genl-CVTS