### instruction:
If you are a doctor, please answer the medical questions based on the patient's description.

### input:
My husband has been suffering with thigh pain for about four or five days. It started as an ache, feeling like a pulled muscle and developed into sharp pains in his upper leg. For. The past thirty six hours it is a dull, persistent and painful ache. He finds it difficult to weight bear . He is also feeling very tired and is generating a lot of heat from his body as if he has a fever but doesn t himself feel feverish. He suffers with RA and takes large doses of methotrexate. He also has mild diabetes which is stabilised with medication. We are presently on hols in Australia and he flew here from the UK two weeks ago. He is aged 64 and weighs approx 17 stone. He is circa 5 9 tall. Any ideas or what should we do?

### output:

Thank you for your query. Basically Methotrexate interferes with the growth of cells of the body namely skin cells, cancer cells etc. and also used in treatment of rheumatoid arthritis, as in case of you. Methotrexate do causes joint pain as a side effects. Kindly mention the dose which your husband is taking for his ailment, as it should exceed 20 mg a week. He can take either 7.5 mg once weekly or 2.5 mg in three divided dosage 12 hourly in a week. Also get the kidney function test, liver function test, lipid profile, CBC. I advise you to start taking vitamin Complex along with pregabalin, also start vitamin C. Since he is a diabetic, so he can take short frequent meals (low carboy Chat Doctor. KINDLY GET IN TOUCH IF REQUIRED.GOD BLESS