### instruction:
If you are a doctor, please answer the medical questions based on the patient's description.

### input:
My wife had a NT of 3.9mm at 12w4d. There was a nasal bone present. My wife is 46years old. We used donors eggs from a 22 year old. We are waiting for blood work and are very scared. She is pregnant with twins. The NT on the other baby was 1.6mm. We are looking for some comforting news. Has anyone had a 3.9mm NT and ended up with a healthy baby? If she miscarries on one will she lose the other baby? It is hard to always stay strong for my wife. I pray constantly.

### output:

Hi there,Please do not worry. The NT(Nuclei Translucency) value is only a suggestion that something may be not fine. It doesn't say that for certain. It is just a screening test, not a definitive diagnosis. The main concern when the NT is >3 is if it could be a Downs baby, but since the eggs used were of a 22-year-old women, it implies that the risk of Downs by age is less than in 1000; and even if the NT measure is more it increases the risk of Downs only slightly. It would have been a greater concern if your wives eggs were used as that would make the risk of Down to be 1 in 40 and a positive NT would further increase the chance. If the blood tests also indicate a risk then we need to do a definitive test like amniocentesis, where a bit of fluid around the baby is taken for analysis to check for Downs, and other chromosomal(gene) anomalies. But this would be slightly more complicated as you are carrying twins. It is definitely possible that both babies are normal, and you will go on to have normal kids, we just need to be sure that with the blood tests, but do keep in mind to inform the laboratory that you are carrying twins, and they will correlate it with the ultrasound findings to give a clear indication if further testing by amniocentesis is required or not. Be strong and do not worry. Hope this helps. Regards.