### instruction:
If you are a doctor, please answer the medical questions based on the patient's description.

### input:
I have recently been seeing several doctors over the last 8 mothts due to some odd symptoms, one pupil was VERY dialated and the other was fine. I saw a Neurologist, had the CT Scan and the MRI, and a battery of blood tests (including the one for siphilys) Everything came out clear except that my ANA was abmormally high. I was then sent to a rheumatologist who did another blood test and seems to think I may have Lupus, but it is not conclusive. I am in Wait and See mode and have had a few things pop up and I m not sure if it is connected to the Lupus possiblitiy? or is it something else that I should get checked out? or am I over sensitive to symptoms because of the possibility of Lupus? I m now having cronic lower back pain that is worse in the morning and gets a little better as I move through the day (I ve been taking advil), aslo when I m lying in bed and move to look above my head, I feel a painful pressure in my head that goes away once I lie flat and I have been putting on a little more weight than normal for me. I d appreciate your opionion.

### output:

Hi, Thank you for your query. I can understand your concerns. Systemic Lupus Erythematous (SHE) does not involve axial joints i.e. spinal joints giving rise to chronic low back pain. There are many conditions associated with positive ANA. Anti-double- stranded DNA (anti-ds-DNA)-more specific for the diagnosis of SHE and can be detected by radio-immuno-assay. Predictive value of a positive test is >90 % for SHE if present in high tier. SLE can cause organic psychosis, neurosis, Cranial nerve involvement. That can explain pupillary abnormality. There is a possibility of overlap syn Chat Doctor. I suggest you to undergo the following tests:Serum anti-U1RNP antibodyThyroid function test : serum free T3,freeT4 & TSH assay, as you are gaining weight. Regards 