### instruction:
If you are a doctor, please answer the medical questions based on the patient's description.

### input:
my mother is suffering from Tb..she is having  Tb in her chest as well as in her spine which is causing lot of trouble for her..treatment is going on for almost last three months still no sign of relief could b seen..doctors have preferred her to tak complete bed rest for another two months..plz suggest what to do??

### output:

Thanks for posting your question on Chat Doctor! I appreciate your concern towards your mothers' illness. Tuberculosis is a chronic contagious disease caused by a slowly multiplying organism and having ability to develop resistance to commonly used antibiotics. So, to overcome these problems the treatment involves the use of four or more antibiotics given in two phases. For TB affecting the spine the following regimen is used by most of the centers:In the initial phase Isoniazid, Rifampicin, Pyrazinamide and Ethambutol are given once daily for two months and in the continuation phase Isoniazid and Rifampicin are administered once daily for a period of 12-18 months depending upon the severity of the infection involving the spine. Vitamin pyridoxine is supplemented along with Isoniazid to prevent its side effect involving the nerves. A regular followup is required to see whether the patient is taking the medication or not, improvement in the general condition, appetite, weight gain, fever etc. Lab investigations done include ESR, Chest X-ray sputum analysis to check the response to the treatment. Since your mother is having TB of spine and the fact that treatment is a bit longer, therefore it takes time to show the improvement. However, you are advised to consult your physician. Wishing your mother a speedy recovery from the illness. Regards!