### instruction:
If you are a doctor, please answer the medical questions based on the patient's description.

### input:
HI. I have panhypopifuitarism & was recently prescribed Amlodopine 5mg & Indapamide 2.5mg to reduce blood pressure. My blood pressure is better but I am getting dreadful muscle & joint pain, in my arms & legs...esp calves. Am also v tired & brain fogged...and finding I wake several times during thd night. Could these drugs be causing my pain?

### output:

Hi, thank-you for providing the brief history of you. As to know that what is panhypopituitarism is the below-mentioned will help you understand. BackgroundThe pituitary gland is called the master endocrine gland of the body because it controls the function of other endocrine organs. The anterior pituitary produces the hormones' thyrotropin (thyroid-stimulating hormone [TSH]), corticotropin (a Chat Doctor.  The anterior pituitary is controlled by specific hypothalamic-releasing hormones. The posterior pituitary produces desmopressin (antidiuretic hormone [ADH]) and oxytocin. Panhypopituitarism is a condition of inadequate or absent production of the anterior pituitary hormones. It is frequently the result of other problems that affect the pituitary gland and either reduce or destroy its function or interfere with hypothalami secretion of the varying pituitary-releasing hormones. Panhypopituitarism can be the end result of various clinical scenarios. The signs and symptoms are diverse. Since the pituitary gland is the main of all, any abnormality in that can lead to various issues including the growth hormone. Consulting a physician can help further into the depth of the situation. Also, fatigue is common due to disturbed metabolism and may lead to muscle & joint aches and pains. Undergoing physical therapy will help improve the metabolism & immune system. Regards Jay In