### instruction:
If you are a doctor, please answer the medical questions based on the patient's description.

### input:
dear sir I am suffering from Psoriasis for the past one decade.I am currently only using Propysalic ointment and one mosturizer. I feel nausea when i take methotraxate. I have also tried Homeopathic and ayurvedic medicines but none seems to work. Currently my condition has worsened and the ointment is not able to control the same.Kindly help me Ved Prakash

### output:

Hello Led Prakash. Thanks for sharing your query here. Topicals in the form of Proposal ointment can be used if involvement is up to a certain percentage of body area by Psoriasis. Beyond a specific limit, you will need oral /injectable therapy which unfortunately has the potential if side effects, if not monitored closely. For a chronic condition like psoriasis, treatment regimen is modified according to the severity of disease, which might be different in different times of the year. So, a close follow-up with your dermatologist is important for optimum result and achieving a remission. For the methotrexate that you are using, side effects like nausea and vomiting may be dose-dependent. Therefore, several physicians consider adjusting the dose or modifying the mode of intake to eliminate the problem. The total dose of Methotrexate can be divided & taken over 2 days every week; or you may take it at bedtime, if taking during the day causes nausea; it can also be taken after food, instead of before. Still if nausea persists, you may consider switching over to injectable Methotrexate once a week. Several other Chat Doctor. I would advise you to discuss these with your dermatologist and continue the therapy. Hope the is helpfulTake care!