Hi,I am Dhilipkumar kumar of age 26 Year,I have been affected by Hepatitis B from 1year.My Current status is HBsAG Positive (quatity = 210 iu/ml) HBeAg Negative (qu = 1.5) HBV DNA is In the the pegylated interferon alpha 2 b (treatment of 48 week.)( this week is my 13th week of PEG-IFN) How to loss HBsAG. Please Help me.Regards.Sankar
Hello. Thanks for asking query at Chat Doctor. As I understand you are suffering from chronic hepatitis B (E antigen negative), currently on PEG IFN therapy. You have not given details of the baseline DNA level or at the end of 12 week therapy. Basic aim of chronic hepatitis B treatment is brought down the DNA level to 0(NIL), normalize SGPT (ALT) and prevent the chances of chronic liver disease or liver cancer. Secondary aim is to get Bag negative, which may not happen to everybody who is treated. It may happen in about 7-8% of those who are treated with PEG IFN, but definitely primary objectives of treatment are more important and will happen. You can also discuss these things with your hepatologist who initiated the treatment. Take care.