have B-cell defiance because serum levels of IgE and IgD were low compared to levels of IgG and IgM. There were low levels of IL-2,4,6 that leads to the cytotoxic CMI leading to low levels of B-cell.You need to comment on these result in a scientific fashion giving clear answer supported by facts.
Hi, Welcome to Chat Doctor. B-cells are white blood cells present in the blood which are responsible for humoral response of the body to any infection. Humoral response is the production of antibodies which are specific to the pathogen causing infection and these antibodies attach themselves to the pathogen causing its death. Antibodies are usually immunoglobulins (IG). There are 5 types of Immunoglobulins in our body. Egg, IGA, IGM, IGE and ID. If there is a B-cell deficiency, there will be low levels of Immunoglobulins produced.IL-2, 4 and 6 are factors which are called cytokines which modulate the cell differentiation and hence affect the cell mediated immunity. Deficiency of these factors may cause depletion of both B cells and T cells. Thanks