Im a 50 year old female who smokes.  Recently I have been experiencing shortness of breath - for about 2 months.  Now I have sharp twinges in the centre of my chest, a little over to the right.  They hyave started more recently, in the last couple of weeks and happen randomly throughout the day , during activity and at rest.  I also have an under active thyroid - for 10 years.  Tiredness has been put down to end of the menopause and age.
Thanks for your question on Chat Doctor. I can understand your concern. Since you are a active smoker, we should rule out heart and lung related diseases because both of them can cause chest discomfort and breathlessness. So consult doctor and get done 1. ECG and 2d echo to rule out heart diseases. 2. Clinical examination of respiratory system and PFT (pulmonary function test) for the diagnosis of bronchitis. You may need cardiac supportive Chat Doctor.  In any case, you should quit smoking as soon as possible. Don't worry, you will be alright. First diagnose your self and then Start appropriate treatment. Hope I have solved your query. I will be happy to help you further. Wish you good health. Thanks.