Dx colon CA met to liver Sep 2008, Colon resection Oct 2008, Folfiri Jan 2009-2012, Folfox 2012 6mo did not work, Cetuximab/Irinotecan Feb 2013- Jul 2013.  1st 3 mo of cetuximab/Irin was amazingly effective. Metastases and liver lesions under control with little or no activity on PET until 2nd 3mo of cetuximab. Now new multiple lesions in liver, paraortic and carinii nodes reflared, and new small lesions on pancreas, omentum fat and peritoneum.My current onc has no more alternatives for me except for a phase 1 trial for one specific genome that may be sensitive to tx. Trial is in Dallas.  Id like a second opinion to see if a more aggressive proven tx is available. 61yrs, no pain, otherwise good health and activity. Never mind, I already know the answer. A 2nd opinion from a reliable doc is always helpful to make the right decision.
Your case is a stage 4 ca colon, as u taken first line of chemotherapy with two types of regime. Now recurrence of liver lesions and metastasis indicates as the rituximab/ irinotectan what you are receiving is either not acting or already it's your advanced stage. As the oncologist suggest going for new treatment is one of the best option and only hope for the your disease. Hope u get well soon and also involving in trials help in research activity of malignancies