My 88 year old  mothers blood test showed no report of atypical lymphocytes in November, 2012.  In March, 2013 itshowed .l and in June, 2013 it read .8.  We cannot think of any infections  going on at the times.  We will testagain next week.  Should it read anything again, should I be concerned and what should be our next step to take?
Hello and welcome to Chat Doctor, Atypical lymphocytes are seen in viral infections and lymphoid malignancies. You have mentioned that the number of atypical lymphocytes increased from 1 in March 2013 to 8 in June 2013. Yes, a repeat test should be done. The possibility of infection is high since, the number of atypical cells is low. Is there any associated enlarged lymph node(s). Sometimes lymphoid malignancy of lymph node (lymphoma) can spill over into the blood and these cells are reported as atypical lymphocytes. If any enlarged lymph node is present, an aspiration cytology/ biopsy needs to be done. If lymphoid malignancy is detected, immune markers should be done. Get the test done and consult your hematologist to know the cause of atypical lymphocytes (if present this time too). Thanks and take care Chat Doctor. 