My son, 13 months old, had lab work done to determine whether or not he has his dads hereditary protein c defieciency. Everything came back normal except for his protein s level. It was 45, the normal range for this hospitals lab is 65-100. My son s doctor is unfamiliar with this lab and said she would research it and get back to us. Can you please help us? Does his level of 45 mean he has protein a deficiency or does it still have time to rise to normal levels? Thank you.
Hello, Welcome to the ChatDoctorThankyou for your questionImmunologic methods for the measurements of protein C include enzyme linked immunosorbant assay (ELISA), radioimmunoassay and electroimmunoasay. Normaly in adults it approximates 70 to 140 percent of protein C antigen level of whole pooled plasma level. But in infants total protein is normal at lower level as compare to adults. And Also infants and neonates have lower levels of protein C than their adult counterparts, therefore age based normal ranges must be derived separately for the child Chat Doctor. Hopefully my answer will be helpful.