T cell acute lymphoblastic leukaemia presenting with sudden onset right oculomotor nerve palsy with normal neuroradiography and cerebrospinal fluid studies
- Vijaya Raj Bhatt1,
- Muniba Naqi1,
- Rajiv Bartaula1,
- Srujitha Murukutla1,
- Sulagna Misra1,
- Muhammad Popalzai2,
- Kavitha Paramanathan2,
- Qun Dai2
- 1Department Of Medicine, Staten Island University Hospital, Staten Island, New York, USA
- 2Division Of Hematology/Oncology, Department of Medicine, Sanford R Nalitt Institute for Cancer and Blood Related Diseases, Staten Island University Hospital, Staten Island, New York, USA
- Correspondence to Dr Srujitha Murukutla,
Leptomeningeal disease presenting with neurological dysfunction is not uncommon in leukaemia. However, it is often accompanied by abnormalities in cerebrospinal fluid (CSF) studies and/or neuroradiography. Here, the authors describe a case of a young patient presenting with sudden onset right oculomotor nerve palsy with normal neuroradiography and CSF studies, who was subsequently diagnosed to have T cell acute lymphoblastic leukaemia (T-ALL). This case highlights that neurological manifestations can be the initial presenting feature of T-ALL and can occur suddenly despite normal neuroradiography and initial CSF studies.
Competing interests None.
Patient consent Obtained.