Rates and radicality of amino acid substitution vs. expression level and ubiquity. Relationship between relative substitution rate (Ka/Ka; A, C) and mean absolute change of polarity (|ΔP|; B, D) and log mean gene expression rate in whole fly (A, B) and coefficient of variation of expression rate across larval and adult tissues (C, D). Expression data from . Solid lines: regressions significant at P<0.0001; dashed lines: regression without significant terms (shown for a comparison). Second-degree polynomial regression lines are shown when the quadratic term is significant, otherwise a linear regression is used.
Yampolsky and Bouzinier BMC Genomics 2010 11(Suppl 4):S10 doi:10.1186/1471-2164-11-S4-S10