Lymph nodes - not lymphoma
Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 7 November 2013, last major update March 2013
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
- Develop from lateral plate mesoderm (on either side of intermediate mesoderm)
- First, lymphatic sacs arise from endothelial outgrowths of large central veins at week 5
- Second, lymphatic plexus develops from lymphatic sacs
- Third, plexuses are invaded by mesenchymal cells that proliferate and aggregate to form lymph nodes
- Small collections of lymphoblasts are present by first trimester
- By second trimester, cortex is distinguishable from medulla and primary follicles are present
Animation of lateral plate mesoderm
Development of lymph node
End of Lymph nodes - not lymphoma > Embryology
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