| smiles,lipo | |
| Cn1c(CN2CCN(CC2)c3ccc(Cl)cc3)nc4ccccc14,3.54 | |
| COc1cc(OC)c(cc1NC(=O)CSCC(=O)O)S(=O)(=O)N2C(C)CCc3ccccc23,-1.18 | |
| COC(=O)[C@@H](N1CCc2sccc2C1)c3ccccc3Cl,3.69 | |
| OC[C@H](O)CN1C(=O)C(Cc2ccccc12)NC(=O)c3cc4cc(Cl)sc4[nH]3,3.37 | |
| Cc1cccc(C[C@H](NC(=O)c2cc(nn2C)C(C)(C)C)C(=O)NCC#N)c1,3.1 | |
| OC1(CN2CCC1CC2)C#Cc3ccc(cc3)c4ccccc4,3.14 | |
| COc1cc(OC)c(cc1NC(=O)CCC(=O)O)S(=O)(=O)NCc2ccccc2N3CCCCC3,-.72 | |
| CNc1cccc(CCOc2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2C)n1,.34 | |
| COc1ccc(cc1)C2=COc3cc(OC)cc(OC)c3C2=O,3.05 | |
| Oc1ncnc2scc(c3ccsc3)c12,2.25 | |
| CS(=O)(=O)c1ccc(Oc2ccc(cc2)C#C[C@]3(O)CN4CCC3CC4)cc1,1.51 | |
| C[C@H](Nc1nc(Nc2cc(C)[nH]n2)c(C)nc1C#N)c3ccc(F)cn3,2.61 | |
| O=C1CCCCCN1,-.08 | |
| CCCSc1ncccc1C(=O)N2CCCC2c3ccncc3,1.95 | |
| CC1CCCCC1NC(=O)c2cnn(c2NS(=O)(=O)c3ccc(C)cc3)c4ccccc4,1.34 | |
| Nc1ccc(cc1)c2nc3ccc(O)cc3s2,3.2 | |
| COc1ccc(cc1)N2CCN(CC2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NCC#N,1.6 | |
| CCC(COC(=O)c1cc(OC)c(OC)c(OC)c1)(N(C)C)c2ccccc2,3.77 | |
| COc1cc(ccc1N2CC[C@@H](O)C2)N3N=Nc4cc(sc4C3=O)c5ccc(Cl)cc5,3.15 | |
| CO[C@H]1CN(CCN2C(=O)C=Cc3ccc(cc23)C#N)CC[C@H]1NCc4ccc5OCC(=O)Nc5n4,.32 | |
| CC(C)(CCCCCOCCc1ccccc1)NCCc2ccc(O)c3nc(O)sc23,2.92 | |
| Clc1ccc(cc1)C(=O)Nc2oc(nn2)C(=O)Nc3ccc(cc3)N4CCOCC4,1.92 | |
| COc1ccc(Oc2cccc(CN3CCCC(C3)N4C=C(C)C(=O)NC4=O)c2)cc1,3.17 | |
| OC(=O)c1cccc(c1)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,2.17 | |
| CNCC[C@@H](Oc1ccccc1C)c2ccccc2,1.2 | |
| Clc1ccc(N2CCN(CC2)C(=O)CCCc3ccncc3)c(Cl)c1,3.93 | |
| COc1cnc(nc1N(C)C)c2ccccn2,1.9 | |
| C(CCCCNc1cc(nc2ccccc12)c3ccccc3)CCCNc4cc(nc5ccccc45)c6ccccc6,2.27 | |
| CSc1c(cnn1c2ccc(cc2)C(=O)O)C(=O)NC3C4CC5CC(CC3C5)C4,1.2 | |
| CNC1=Nc2ncccc2C(=NC1c3cccs3)c4occn4,1.14 | |
| CS(=O)(=O)C1(CC1)c2cc(nc(n2)c3cccc4[nH]ccc34)N5CC6CCC(C5)O6,2.6 | |
| CN([C@@H]1CCN(Cc2ccc(cc2)C(F)(F)F)C[C@@H]1F)C(=O)Cc3ccc(cc3)n4cnnn4,3.3 | |
| CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C,3.94 | |
| CS(=O)(=O)c1ccccc1C(=O)NC[C@@H](O)CN2CCC(CC2)Oc3ccc(Cl)c(Cl)c3,2.34 | |
| O=C(NCc1ccncc1)c2ccc(Oc3ccccc3C#N)cc2,2.57 | |
| CN(C)c1ccnc2sc(C(=O)NCc3ccccc3)c(N)c12,3.62 | |
| CN1CCN(CC1)c2ccc3N=CN(C(=O)c3c2)c4cc(NC(=O)c5cscn5)ccc4C,2.06 | |
| Cn1cncc1c2c3C(=O)N(CC4CC4)C(=O)N(CC5CC5)c3nn2Cc6ccnc7ccc(Cl)cc67,4.33 | |
| COc1ccc2ncc(C#N)c(CCN3CCC(CC3)NCc4cc5SCOc5cn4)c2c1,2.55 | |
| CNC(=O)C1(CCN(CC[C@H](CN(C)C(=O)c2c(OC)c(cc3ccccc23)C#N)c4ccc(Cl)c(Cl)c4)CC1)N5CCCCC5=O,2.78 | |
| OB1N(C(=O)Nc2ccccc12)c3ccccc3,1.4 | |
| CC(C)N(CCC(C(=O)N)(c1ccccc1)c2ccccn2)C(C)C,-.54 | |
| NC(=NC#N)c1sc(Nc2ccccc2)nc1N,2.91 | |
| CCS(=O)(=O)c1ccc(c(C)c1)c2cc(ccc2O[C@H](C)C(=O)O)C(F)(F)F,-.4 | |
| OC(=O)COc1ccc(cc1c2cc(ccc2F)C#N)C(F)(F)F,-.16 | |
| COc1ccc(cn1)C2=Cc3c(C)nc(N)nc3N([C@@H]4CC[C@H](CC4)OCCO)C2=O,2.2 | |
| CC(Nc1ncnc2ccccc12)c3ccccc3,3.4 | |
| CC(C)c1ccc2Oc3nc(N)c(cc3C(=O)c2c1)C(=O)O,1.1 | |
| O[C@@H](CNCCCOCCOCCc1cccc2ccccc12)c3ccc(O)c4NC(=O)Sc34,2.28 | |
| COc1ccccc1Cn2c(C)nc3ccccc23,3.47 | |
| OC(=O)c1ccc(NC(=O)c2cc(OCc3ccccc3F)cc(OCc4ccccc4F)c2)nc1,3 | |
| NC(Cc1c[nH]c2ccccc12)C(=O)O,-1.17 | |
| OC(=O)CCC[C@H]1[C@@H](Cc2ccccc12)NC(=O)c3cc4cc(F)ccc4[nH]3,1.95 | |
| CCNC(=O)c1cc2c(c(cnc2[nH]1)c3cncc(c3)C(=O)O)n4ccc(n4)C(F)(F)F,-.99 | |
| C[C@H](NC(=O)c1c(C)nn(C2CCCC2)c1NS(=O)(=O)c3ccc(C)cc3)C(C)(C)C,2 | |
| N(c1ccccc1)c2cc(Nc3ccccc3)[nH]n2,3.8 | |
| COCCNC(=O)c1cccc(Nc2ncc3cc(ccc3n2)c4ccncc4)c1,3.21 | |
| CCC(CC)NC(=O)c1cnn(C)c1NS(=O)(=O)c2ccc(C)cc2,.36 | |
| NC(=O)c1cc(F)cc(O[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)c1,2.14 | |
| O=C1NC(=NC(=C1C#N)c2ccccc2)SCCc3ccccc3,1.71 | |
| OC(C(=O)OC1CN2CCC1CC2)(c3ccccc3)c4ccccc4,1.19 | |
| Cc1ccccc1NC(=O)CCS(=O)(=O)c2ccc(Br)s2,2.7 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(cc3)C(=O)N(C)C)ncc2F,2.77 | |
| COc1cccc(c1)c2c[nH]c(n2)c3ccccc3,3.8 | |
| O=C(COc1ccccc1)c2ccccc2,2.87 | |
| COc1cc2ncc(C(=O)N)c(Nc3ccc(F)cc3F)c2cc1NCCN(C)C,1.91 | |
| CO[C@@H]1CC[C@@]2(CC1)Cc3ccc(OCC(C)C)cc3C24N=C(C)C(=N4)N,3.4 | |
| COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCCC4,3.13 | |
| O=C1CCOc2cc(COc3ccccc3)ccc12,3 | |
| Clc1cccc2cn[nH]c12,2.33 | |
| CNC(=O)c1ccc(CC(=O)N(C)C2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)cc1,2.8 | |
| COCCNCc1ccc(CCNC[C@H](O)c2ccc(O)c3NC(=O)Sc23)cc1,-.54 | |
| Cn1cncc1c2c3C(=O)N(CC#C)C(=O)N(CC4CC4)c3nn2Cc5ccnc6ccc(Cl)cc56,3.16 | |
| C[C@H](NC(=O)c1cccnc1Oc2ccccc2)c3ccccc3,2.91 | |
| Clc1ccc(CN2CC3CNCC(C2)O3)cc1C(=O)NCC45CC6CC(CC(C6)C4)C5,1.55 | |
| COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1,.2 | |
| Cc1cc(CCC2CCN(CC2)S(=O)(=O)CC3(CCOCC3)N(O)C=O)c(C)cn1,1.43 | |
| C[C@H](Nc1ncc(F)c(Nc2cc([nH]n2)C3CC3)n1)c4ncc(F)cn4,2.47 | |
| CC(=O)Nc1ccc2c(c1)c(cn2CCCO)c3cc(NC4CC4)n5ncc(C#N)c5n3,2.48 | |
| CC1COc2c(N3CCN(C)CC3)c(F)cc4C(=O)C(=CN1c24)C(=O)O,-.45 | |
| CC1(CC1)c2nc(ncc2C(=O)N[C@@H]3C4CC5CC3C[C@@](O)(C5)C4)N6CCOCC6,2 | |
| COC(=O)c1ccc(C)c(NS(=O)(=O)c2ccc3N(C)SC(=O)c3c2)c1,2.6 | |
| COc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O,3.5 | |
| CNCCCC12CCC(c3ccccc13)c4ccccc24,.89 | |
| Oc1cc(nc2ccnn12)c3ccccc3,1.3 | |
| Fc1cc(cc(F)c1C2=CCN(CC2)C=O)N3C[C@H](COc4ccon4)OC3=O,2.01 | |
| CC(C#C)N1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c3C1=O)c6cncn6C,3.59 | |
| C[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1C(=O)Cc3ccccc3,.18 | |
| COc1cc(Nc2nc(N[C@@H](C)c3ncc(F)cn3)ncc2Br)n[nH]1,2.6 | |
| Cc1nc(C)c(nc1C(=O)N)c2ccc([C@@H]3CC[C@@H](CC(=O)O)CC3)c(F)c2,1.3 | |
| COc1ccnc(CCc2nc3c(C)ccnc3[nH]2)c1,2.1 | |
| Cc1cc(CCCOc2c(Cl)cc(cc2Cl)C3=NCCO3)on1,3.72 | |
| CN(C)C(=O)c1ccc(CN2CCc3cc4nc(N)sc4cc3CC2)cc1,1.72 | |
| COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12,1.65 | |
| CCN1CCN(CC1)c2ccc(Nc3cc(ncn3)N(C)C(=O)Nc4c(Cl)c(OC)cc(OC)c4Cl)cc2,3.7 | |
| CC(C)N(CCCNC(=O)Nc1ccc(cc1)C(C)(C)C)C[C@H]2O[C@H]([C@H](O)[C@@H]2O)n3cnc4c(N)ncnc34,2.2 | |
| CCN(CC)CCCCNc1ncc2CN(C(=O)N(Cc3cccc(NC(=O)C=C)c3)c2n1)c4c(Cl)c(OC)cc(OC)c4Cl,2.04 | |
| CCSc1c(Cc2ccccc2C(F)(F)F)sc3N(CC(C)C)C(=O)N(C)C(=O)c13,4.49 | |
| COc1ccc(Cc2c(N)n[nH]c2N)cc1,.2 | |
| CCN(CCN(C)C)S(=O)(=O)c1ccc(cc1)c2cnc(N)c(n2)C(=O)Nc3cccnc3,2 | |
| CC1=CN([C@H]2CCCN(C2)S(=O)(=O)c3ccc(O)c(Oc4ccccc4)c3)C(=O)NC1=O,1.49 | |
| C1Oc2ccccc2C3=NN(CC13)c4ccccc4,4.28 | |
| CNC(=C[N+](=O)[O-])NCCSCc1oc(CN(C)C)cc1,-.95 | |
| CC(C)CC(N1NC(=O)c2nc3cc(Cl)ccc3c(O)c2C1=O)c4ccncc4,1.64 | |
| FC(F)c1nc2ccccc2[nH]1,2.02 | |
| O[C@@H](CNC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)COc3cccc(c3)C#N,3.09 | |
| COc1cc2ncc(C(=O)N)c(Nc3ccc(F)cc3F)c2cc1N4CCN(C)CC4,2.18 | |
| Oc1ccccc1OC(=O)c2cccc3ccccc23,4.4 | |
| COc1ccccc1CNc2cc(C)ccn2,3.28 | |
| Nc1nc(Nc2cccc(Br)c2)c3nc[nH]c3n1,3.04 | |
| Nc1c2CCN(c3ccccc3)c2nc4ccc(Br)cc14,3.12 | |
| COc1cc(OC)c(cc1NC(=O)CCC(=O)O)S(=O)(=O)N(c2ccc(C)cc2)c3ccc(C)cc3,.06 | |
| OC(C(=O)c1ccc(F)cc1)c2ccc(F)cc2,2.49 | |
| CC(C)C[C@H](N)c1oc(nn1)S(=O)(=O)Cc2ccc(F)cc2,1.11 | |
| CC(C)COc1cccc(c1)C(=O)Nc2ccc(C)c(c2)C(=O)Nc3cccnc3,2.81 | |
| COc1ccc(OC)c(CNC(=O)c2cccnc2Oc3ccccc3)c1,3.52 | |
| NC1(CCC1)c2ccc(cc2)c3nc4C=CN5C(=O)NN=C5c4cc3c6ccccc6,2.5 | |
| CC(C(Cc1nc2ccccc2[nH]1)c3nc4ccccc4[nH]3)c5ccccc5,4.48 | |
| Clc1ccc2OCC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,1.33 | |
| OC(=O)Cc1ccc(cc1)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,1.83 | |
| COc1cc2ncc(C(=O)N)c(Nc3cccc(Cl)c3F)c2cc1OC,3.6 | |
| CN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)C4CCC4,3.2 | |
| NC(=N)NC(=O)c1nc(Cl)c(NCc2ccccn2)nc1N,-.56 | |
| Nc1c(NC2CC3CCC2C3)nc(nc1N4CCOCC4)C#N,3.53 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)NCc4c(F)cccc4F,4.3 | |
| NC1(CCN(CC1)c2ncnc3[nH]ccc23)C(=O)NCc4ccc(Cl)cc4,2.88 | |
| CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24,3.08 | |
| Cc1ncc(nc1C(=O)N)c2ccc(cc2)[C@@H]3CC[C@@H](CC(=O)O)CC3,1 | |
| Cn1ncnc1COc2nn3c(nnc3cc2C(C)(C)C)c4cc(F)ccc4F,2.4 | |
| CNCC[C@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2,1.89 | |
| Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)cc4Cl,1.52 | |
| O=C1C=COc2cc(OCc3ccccc3)ccc12,3.33 | |
| [O-][S+](c1ccccc1)c2ccc3nnnn3n2,.79 | |
| [O-][N+](=O)c1ccc2OC(CN(c2c1)c3cccc[n+]3[O-])(C(F)F)C(F)F,3.2 | |
| CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1,.1 | |
| Cc1ncc(nc1c2ccc(cc2)[C@@H]3CC[C@H](CC3)C(=O)O)C(=O)N,.22 | |
| Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3)s2)s1,2 | |
| COc1cc(OC2CCN(CC2)C(=O)C)ccc1Nc3ncc(Cl)c(n3)c4cnc5ccccn45,4 | |
| COc1ccc(cc1)C2=CC(=O)c3ccccc3N2,2.71 | |
| COC1\C=C\OC2(C)Oc3c(C)c(O)c4C(=O)C(=CC(=O)c4c3C2=O)NC(=O)\C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(=O)C)C1C)\C,.7 | |
| CN1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c6cc(cn6C)C#N)c3C1=O,3.67 | |
| CN1SC(=NC1=O)NC(=O)c2cccc(Cl)c2,.87 | |
| Cc1ccc(cc1NC(=O)c2ccc(OCc3ccccn3)cc2)c4nccn4C,2.83 | |
| CC(=O)Nc1ccc(cc1)C(=O)Nc2ccccc2N,.82 | |
| Oc1ccc2C(=O)C=C(Oc2c1)N3CCOCC3,1 | |
| Oc1nc(nc2CCSCc12)c3ccc(cc3)C(F)(F)F,3.07 | |
| Clc1ccc(N2CCN(CC2)C(=O)COCc3cscn3)c(Cl)c1,3.07 | |
| Oc1ccc(cc1)N2C=Nc3cc(O)ccc3C2=O,1.6 | |
| O[C@@H](CNCCc1ccccc1CNCCc2ccccc2F)c3ccc(O)c4NC(=O)Sc34,1.58 | |
| OCC(CO)N1C=Cc2c(NC(=O)CC34CC5CC(CC(C5)C3)C4)cccc2C1=O,2.62 | |
| COc1ccc(c(OC)n1)c2c(F)ccc3c(N)c(nnc23)C(=O)NC4CC4,3.37 | |
| Clc1ccccc1c2cnn[nH]2,2.68 | |
| NC(=O)c1ccc(Oc2cccc3cccnc23)c(c1)[N+](=O)[O-],1.7 | |
| NC(=O)Nc1cc(sc1C(=O)N)c2cccc(O)c2,2.21 | |
| Nc1ccc(cc1)S(=O)(=O)Nc2nccs2,-.37 | |
| COC(=O)C1=Nc2c(N[C@H](C)CO)nc(SCc3cccc(F)c3F)nc2NC1=O,2.49 | |
| COc1cccc(NC(=O)Cn2cc(Oc3ncnc4cc(OC)c(OC)cc34)cn2)c1,3.11 | |
| CC1CCc2cc(F)cc3C(=O)C(=CN1c23)C(=O)O,.74 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cn3c(C)nc(Cl)c3Cl)c2C(=O)N4CC[C@@H](O)C4,1.61 | |
| O=C(NC1(CC1)C#N)[C@@H]2CCCC[C@H]2C(=O)N3CCN(CC3)c4ncc(C#N)s4,1.2 | |
| Cc1ccc(NC(=N)N)cc1C,-1.34 | |
| Clc1ccc(cc1C(=O)NCC2CCCCC2)N3N=CC(=O)NC3=O,1.26 | |
| O=C(Oc1ccccc1)N2CCOCC2,1.3 | |
| CC(C)(C#N)c1cnc(s1)N2CCN(CC2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NC4(CC4)C#N,1.9 | |
| FC(F)(F)c1nnc2ccc(nn12)N3CCCCC3,3 | |
| Cc1c(Sc2ccc(Cl)cc2)c3c(NS(=O)(=O)C)cccc3n1CC(=O)O,.21 | |
| CCCNC(=O)CSc1ccc(cn1)S(=O)(=O)N2CCCC2,1.55 | |
| C[C@@H](Oc1cccc2ncnc(Nc3ccc4c(cnn4Cc5ccccn5)c3)c12)C(=O)N6CCOCC6,2.82 | |
| COc1ccc(Cn2cc3N(CC(C)C)C(=O)N(C)C(=O)c3c2)cc1,3.52 | |
| COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCn4cncn4,3.2 | |
| CCN1CCC[C@H]1CNC(=O)c2c(O)c(Cl)cc(Cl)c2OC,1.09 | |
| CC(=O)Nc1nc(C)c(s1)c2cnc(F)c(NS(=O)(=O)c3sc(C)nc3C)c2,.55 | |
| Cc1ccc2c(c1)c(c(C)n2CC(=O)O)c3ccnc4ccc(cc34)C(F)(F)F,1.78 | |
| CSc1ncccc1C(=O)Nc2nccs2,1.43 | |
| CCOc1ncc(C)c2NC(=C([C@@H](c3ccc(cc3OC)C#N)c12)C(=O)N)C,2.51 | |
| Cc1nc2ccc(Cl)cn2c1c3ccnc(N)n3,2.49 | |
| CC1CC(CC(C)(C)C1)OC(=O)C(O)c2ccccc2,2.31 | |
| C[C@@H](NC(=O)C1CCCCN1C)c2ccc(Nc3ncc4cc(ccc4n3)c5ccncc5)cc2,3.34 | |
| CN(C)C(=O)CN1CCN(CCc2c([nH]c3sc(cc23)C(C)(C)C(=O)N4C5CCC4CC5)c6cc(C)cc(C)c6)CC1,4.13 | |
| CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1CCCN(CCc2ccc(F)cc2)C1)C(C)(C)C,3.12 | |
| NC1(CCC1)c2ccc(cc2)c3ncc4ccncc4c3c5ccccc5,2.2 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NS(=O)(=O)C)C(=O)C(F)(F)F,1.77 | |
| C[C@@H]1CN([C@@H](C)CN1C(=O)c2ccc(cc2)C#N)C(=O)[C@@](C)(O)C(F)(F)F,1.5 | |
| CCOc1ccccc1c2ccc(cc2)c3nc4ccc(F)cc4c(N[C@H](C)C(=O)O)c3C#N,2.5 | |
| Clc1ccc(CC2CCNCC2)cc1C(=O)NCC34CC5CC(CC(C5)C3)C4,1.49 | |
| CC[C@H](NC(=O)c1c(c(nc2ccccc12)c3ccccc3)S(=O)(=O)C)c4ccccc4,3.17 | |
| Fc1ccc(NC(=O)c2cccnc2Oc3ccccc3)cc1,3.19 | |
| CC(CN1CCCCC1)C(=O)c2ccc(C)cc2,1.65 | |
| CC(C)OC(=O)N1CCC(CC1)Oc2ncnc(Nc3ccc(nc3C)S(=O)(=O)C)c2C,2.8 | |
| Cc1ccccc1c2c(C(=O)O)n(CCCOc3cccc4ccccc34)c5ccccc25,3.89 | |
| C[C@@H](NCc1ccccc1c2ccc(CCNC[C@H](O)c3ccc(O)c4NC(=O)Sc34)cc2)c5ccccc5,2.28 | |
| Nc1nc(Nc2ccc(F)c(Cl)c2)c3nc[nH]c3n1,2.75 | |
| CCCSc1nc(N[C@@H]2C[C@H]2c3ccccc3)c4nnn([C@@H]5C[C@H](O)[C@@H](O)[C@H]5O)c4n1,3.97 | |
| CSc1ccc(cc1)N2C(=NC(=NC2(C)C)N)N,-.84 | |
| C[C@@H]1N[S@@](=O)(=NC1=O)c2cccc(c2)c3ccc(C)cc3,1.6 | |
| Nc1nc(N)nc(n1)c2cccc(c2)C(F)(F)F,2.4 | |
| Cc1cccc(CN2CCN(CC2)C(c3ccccc3)c4ccc(Cl)cc4)c1,3.39 | |
| Fc1ccc(cc1)S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,1.79 | |
| OC(=O)COc1ccc(Cl)cc1CN2CCCN(CC2)S(=O)(=O)Cc3ccccc3,1.01 | |
| Clc1cccc(c1Cl)n2nnnc2NCc3ccccc3Oc4ccccn4,3.62 | |
| CN1CCCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3,2.36 | |
| Clc1ccccc1CCNC(=O)c2cc(ccc2Cl)N3N=CC(=O)NC3=O,1.29 | |
| Clc1ccc2C(=O)C3=C(Nc2c1)C(=O)NN(Cc4ccccn4)C3=O,1.1 | |
| C[C@@H](NC(=O)[C@H]1CCCCN1)c2ccc(Nc3ncc4cc(ccc4n3)c5ccncc5)cc2,2.15 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3cccc4ncccc34)c2C(=O)N5CC[C@@H](O)C5,1.98 | |
| C[C@H](NC(=O)[C@@H]1CCCC[C@H]1C(=O)N2CCc3[nH]c4ccc(F)cc4c3C2)C#N,3.5 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NS(=O)(=O)N)C(=O)C(F)(F)F,1.17 | |
| OC(=O)C1CCN(CC1)c2ncccc2c3ccc(Cl)c(c3)C(=O)NCC4CCCCCC4,2.53 | |
| Clc1ccc(CNC(=N)SCCCc2c[nH]cn2)cc1,1.13 | |
| Cc1ccc(cc1)c2cccc(c2)c3nn[nH]n3,1.3 | |
| Cc1ccc2c(n1)c(Sc3ccc(Cl)cc3)c(C)n2CC(=O)O,.35 | |
| CN(C1CCN(C)CC1)c2nccc(Nc3cc(NC(=O)c4ccnc(c4)N5CCOCC5)ccc3C)n2,1.8 | |
| CCCCCC[C@H]1OC(=O)CNC(=O)[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H]1C)[C@H](C)CC)[C@H](C)O,3.2 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2CCN(C2)C(=O)c3ccccc3,.82 | |
| Cc1cnc([nH]1)c2ccc(C)c(NC(=O)c3ccc(OCc4ccccn4)cc3)c2,3.19 | |
| O=C(NCCSCc1ccccc1)c2ccccc2,3.3 | |
| OC(=O)[C@@H](Cc1ccccc1)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,2.5 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3c[nH]c4ccccc34)c2C(=O)N5CC[C@@H](O)C5,2.35 | |
| C[C@H](Nc1cnc(C)c(Nc2cc(C)[nH]n2)n1)c3ccc(F)cn3,1.73 | |
| C(CN1CCCCC1)C2CCc3cc(OCc4ccc(cc4)c5ccccc5)ccc3C2,3.3 | |
| Nc1ccccc1NC(=O)c2ccc(cc2)C3CCN(Cc4ccc(cc4)C(=O)NC5CC5)CC3,2.31 | |
| CC(Cc1cccc(CNCCc2c(Cl)cccc2Cl)c1)NC[C@H](O)c3ccc(O)c4NC(=O)Sc34,2.41 | |
| OCC[C@@]1(CCCNC1)c2ccc(Cl)c(Cl)c2,.61 | |
| COc1ccccc1C(NC(=O)[C@@H]2CCCC[C@H]2C(=O)N3CCN(Cc4ccc(F)cc4)CC3)C#N,3.57 | |
| CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c3ccc(F)c(F)c3)nc4ccccc14,3.13 | |
| CCCNC[C@@H](O)COc1ccccc1C(=O)CCc2ccccc2,1.56 | |
| Oc1c2C(=O)N(NC(=O)c2nc3cc(Cl)ccc13)C(C4CC4)c5ccncc5,.7 | |
| Cc1cc(OC2CCN(CC3CCN(CC3)[C@@](C)(Cc4ccc(F)cc4)C(=O)O)CC2)ccc1Cl,2.08 | |
| O=C(CCc1ccccc1)c2ccccc2,3.77 | |
| CCCCc1ncc(\C=C(/Cc2cccs2)\C(=O)O)n1Cc3ccc(cc3)C(=O)O,-.9 | |
| OC(=O)[C@H](Cc1ccccc1)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,2.5 | |
| C(C(C1CCCCC1)C2CCCCC2)C3CCCCN3,3.02 | |
| COc1cc(Nc2nccc(n2)N(C)c3cc(CO)ccc3C)cc(c1)N4CCOCC4,3.9 | |
| O=C(Nc1nc2C(=O)NC=Nc2s1)c3ccccc3,1.94 | |
| CC[C@H](NC(=O)c1c([S+](C)[O-])c(nc2ccccc12)c3ccc(F)cc3)c4ccccc4,3.72 | |
| CC1=CN([C@H]2CCCN(C2)S(=O)(=O)c3ccc(O)c(Oc4cccc(c4)C(F)(F)F)c3)C(=O)NC1=O,2.27 | |
| COc1cccc([C@H](O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC,1.7 | |
| COc1ccc2nc(N[C@H]3CCC[C@@H](C3)NCc4ccsc4)ccc2c1,2.43 | |
| CN1CCN(CC1)c2ncnc3c2sc4nc(C)cc(C)c34,3.2 | |
| CC(C)(C)OC(=O)N1CCN(CC1)c2ncc(OCc3ccc(cc3)S(=O)(=O)C)cn2,3.27 | |
| O=C(COc1ccccc1)N2CCOCC2,.75 | |
| Cc1nnsc1C(=O)Nc2ccccc2,.97 | |
| CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)O)[C@@H]12,1.07 | |
| CC1=CN([C@H]2CCCN(Cc3ccc(C(=O)O)c(Oc4cccc(c4)C(F)(F)F)c3)C2)C(=O)NC1=O,-.38 | |
| COc1cc(O)cc2OC=C(C(=O)c12)c3ccc(O)cc3,2 | |
| O=C(C1CCCCC1)N2CC3N(CCc4ccccc34)C(=O)C2,2.43 | |
| Cc1ccccc1N2C(=Nc3cccc(C)c3C2=O)Cn4nc(c5ccc(O)c(F)c5)c6c(N)ncnc46,3.55 | |
| Nc1cc(nc2ccc(Nc3cc(nc(N)n3)c4cccc(Cl)c4)cc12)c5ccc(F)cc5,2.5 | |
| O=C1NC=Nc2[nH]ncc12,-.42 | |
| C[C@H](NC(=O)c1c(C)nn(C2CCOC2)c1NS(=O)(=O)c3ccc(C)cc3)C(C)(C)C,.78 | |
| Fc1ccc(SC2=NN3C=NC(=O)C(=C3C=C2)c4c(Cl)cccc4Cl)c(F)c1,2.74 | |
| CC(C(=O)O)n1c(C)c(Sc2ccc(Cl)cc2)c3cc(Cl)ccc13,3.56 | |
| NC(=O)c1sc(cc1N)c2ccccc2,2.33 | |
| Cc1ccc2c(c1)c(c(C)n2CC(=O)O)c3ccnc4cc(Cl)ccc34,1.59 | |
| COc1ccc2ncc(F)c(CCN3CCC(CC3)NCc4cc5OCCOc5cn4)c2n1,1.46 | |
| CS(=O)(=O)c1ccc(cc1)c2cnc(N)c(c2)c3ccc(nc3)C(F)(F)F,2.4 | |
| O=C1CCOc2nc(CCc3ccccc3)ccc12,2.5 | |
| Clc1ccc2OC(=O)Nc2c1,2.16 | |
| CC(C)C(=O)NCCNCC(O)COc1ccc(O)cc1,-.15 | |
| NC1(CCC1)c2ccc(cc2)c3nn4cccc4cc3c5ccccc5,3.3 | |
| OC(=O)COc1ccc(cc1CN2CCN(CC2)S(=O)(=O)c3ccccc3)C(F)(F)F,.4 | |
| CSCCC(NC(=O)c1sccc1Cl)c2nc3ccccc3[nH]2,3.69 | |
| COc1ccnc(CCc2nc3cccnc3[nH]2)c1,1.69 | |
| [O-][N+](=O)c1cccc(c1)C(=O)Nc2nc3ccccc3n2CCN4CCOCC4,3.3 | |
| CC(C)[C@@H](CO)NS(=O)(=O)c1ccc(Cl)s1,2.3 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2cccnc2)NC(=O)OCc3ccccc3)C(=O)C(F)(F)F,3.05 | |
| COc1ccc2nccc([C@H](O)C3CC4CCN3CC4C=C)c2c1,2.16 | |
| N#CC[C@H](C1CCCC1)n2cc(cn2)c3ncnc4[nH]ccc34,2.55 | |
| Clc1ccc(Cl)c(c1)S(=O)(=O)Nc2nccs2,1.14 | |
| O=C1COC2(CCN(CC2)S(=O)(=O)c3ccc(cc3)c4ccc5cnccc5c4)CN1C6CC6,3.32 | |
| COc1ccc(cc1)c2cc(Nc3ccn(C)n3)n4ncc(C#N)c4n2,2.97 | |
| Cc1cc(C(=O)CN2C=C(C=CC2=O)C(F)(F)F)c(C)n1Cc3ccccc3,3.46 | |
| Oc1ccc2nc(sc2c1)c3ccccc3,3.99 | |
| NS(=O)(=O)c1nc2ccccc2s1,1.35 | |
| CS(=O)(=O)c1ccc(c(Cl)c1)c2cc(Cl)ccc2OCC(=O)O,-.75 | |
| OC[C@H]1C[C@H]([C@H](O)[C@@H]1O)n2nnc3c(N[C@@H]4C[C@H]4c5ccc(F)c(F)c5)nc(SCCC(F)(F)F)nc23,3.99 | |
| NC(=O)c1ccccc1OCc2ccccc2,2.5 | |
| CC1CC(=O)Nc2ccccc2N1,.56 | |
| NC(=O)N1c2ccccc2CC(=O)c3ccccc13,1.28 | |
| Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)c4ccccc4)C2,4 | |
| COc1ccc(cc1OC)C2=COc3cc(O)cc(O)c3C2=O,2.8 | |
| CC(=O)Nc1ccc2c(c1)c(Sc3ccc(Cl)cc3)c(C)n2CC(=O)O,.2 | |
| O=C1CCOc2nc(ccc12)C#CC3CCCC3,3 | |
| CN1CCN2C(C1)c3ccccc3Cc4cccnc24,2.82 | |
| COc1ccccc1c2nnc(N)[nH]2,.91 | |
| COc1ccc(cc1OC)N2CCN(CC2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NC4(CC4)C#N,1.4 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccc(NS(=O)(=O)C)cc3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,1.84 | |
| O[C@@H](CNCCSCCCNCCc1ccccc1)c2ccc(O)c3NC(=O)Sc23,.12 | |
| CC(C)(C)NS(=O)(=O)c1cncc(c1)c2ccc3nc(NC(=O)NCC(=O)N4CCOCC4)nn3c2,.96 | |
| CC[C@H](NC(=O)c1c([S+]([O-])C(C)C)c(nc2ccccc12)c3ccccc3)c4ccccc4,3.81 | |
| COc1cc(OC)c(cc1NC(=O)COC(=O)C)S(=O)(=O)N2C(C)CCc3ccccc23,2.07 | |
| C[C@]1(CCCN1c2nc(Nc3cc([nH]n3)C4CC4)c5cccn5n2)C(=O)Nc6ccc(F)nc6,3.16 | |
| CC1CN(C(=O)c2ccccc2)c3ccccc3NC1=O,1.73 | |
| COc1cc2ncn(c3cc(OCc4ccccc4C(F)(F)F)c(s3)C(=O)O)c2cc1OC,.84 | |
| O[C@@H](CNCCCSCCNCCc1cccc(Cl)c1Cl)c2ccc(O)c3NC(=O)Sc23,1.74 | |
| NC(=O)Nc1cc(sc1C(=O)N[C@H]2CCCNC2)c3cccc(F)c3F,1.32 | |
| CC(C)C(=O)Nc1nc(cc2ccccc12)c3ccccn3,2.7 | |
| Nc1nc(N)c2nc(c(N)nc2n1)c3ccccc3,1.16 | |
| C[C@@](O)(C(=O)Nc1ccc(cc1Cl)S(=O)(=O)NCC=C)C(F)(F)F,3.07 | |
| COc1ccc(cc1)C(=O)NCc2cn(nn2)c3cc(C)nc4ccc(OC)cc34,3.5 | |
| Oc1ccc(CCNCCCS(=O)(=O)NCCOCCc2cccc(Cl)c2)c3sc(O)nc13,1.92 | |
| NC12CC3CC(CC(C3)C1)C2,-.98 | |
| CNC(=O)c1cc(c2nc(cc(n2)C3(CC3)S(=O)(=O)C)N4CCOCC4)c5cc[nH]c5c1,1.7 | |
| O=C1Nc2ccccc2C(=O)C=C1,1.02 | |
| CC[C@@H](NC1=C(Nc2cccc(C(=O)N(C)C)c2O)C(=O)C1=O)c3oc(C)cc3,2.32 | |
| Fc1ccc(CN2CCN(CC2)C3=Nn4c(CC3)nnc4C(F)(F)F)cc1,2.8 | |
| Clc1ccc(cc1)C2(CCCC2)C(=O)Nc3oc(nn3)C(=O)Nc4ccc(cc4)N5CCOCC5,3.72 | |
| CC[C@H](NC(=O)c1c(CN(C)C)c(nc2ccccc12)c3ccccc3)c4ccccc4,4.18 | |
| CCOC(=O)Nc1cccc(c1)[C@H](N2CCN(Cc3nc[nH]c3C)CC2)c4ccc(cc4)C(=O)N(C)CC,2.32 | |
| Nc1nc(cs1)c2ccccc2,2.43 | |
| COc1ccnc(CCc2nc3cc(Br)cnc3[nH]2)c1,2.92 | |
| Nc1nnc(c(N)n1)c2cccc(Cl)c2Cl,1.38 | |
| CCOc1ccc2oc(C(=O)NC(CCSC)c3nc4ncccc4[nH]3)c(C)c2c1,4.23 | |
| CCOC(=O)C(CCc1ccccc1)NC2CCc3ccccc3N(CC(=O)O)C2=O,-.2 | |
| COc1ccc(Cl)c(Nc2ncnc3cc(OCC4CCN(C)CC4)c(OC)cc23)c1,2 | |
| CS(=O)(=O)C1(CC1)c2cc(nc(n2)c3cccc(N)c3)N4CCOCC4,1.35 | |
| Nc1ncc(nc1C(=O)Nc2cccnc2)c3ccc(cc3)S(=O)(=O)N4CCOCC4,2.83 | |
| CS(=O)(=O)NCC(NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4ccc(Cl)cc4,2.1 | |
| CN1CCN(CC1)c2ccc(NC(=O)c3oc(Nc4ccccc4F)nn3)cn2,2.36 | |
| CC[C@H](NC(=O)c1c([S+](C)[O-])c(nc2cc(Br)ccc12)c3ccccc3)c4ccccc4,3.18 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4c(F)cc(F)cn34)N5CCN(CC5)C(=O)C,3.2 | |
| CON(C)C(=O)c1c(Cn2c(C)nc(Cl)c2Cl)sc3N(CC(C)C)C(=O)N(C)C(=O)c13,2.23 | |
| NC1(CCN(CC1)c2ncnc3[nH]ccc23)C(=O)NC(C4CC4)c5ccc(Cl)cc5,3.4 | |
| O[C@H](CNC(=O)c1n[nH]c2ccccc12)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,2.95 | |
| COc1cc(N2CCN(C)CC2)c3nc(cc(N(C)C)c3c1)C(=O)Nc4ccc(cc4)N5CCOCC5,3.3 | |
| CN1CCC(CC1)n2cc(c(C)n2)c3cnc(N)c(c3)c4oc5ccccc5n4,3.4 | |
| CC1N(C(=O)c2ccccc2)c3ccccc3NC1=O,2.11 | |
| CC(C)N1CCN(Cc2oc(nc2)c3cc(cc4[nH]ncc34)c5cccc6[nH]ccc56)CC1,3.49 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CN=C1c2ccccc2)NC(=O)OCC(F)(F)F)C(=O)C(F)(F)F,2.37 | |
| Cc1ccc(Cl)c(Nc2ccccc2C(=O)O)c1Cl,2.33 | |
| COc1ccc2N=CC(=O)N(CCN3CC[C@@H](NCc4cc5OCCOc5cn4)[C@@H](O)C3)c2c1,.78 | |
| CCOc1cc2nccc(Oc3cnc(CC(=O)Nc4n[nH]c(CC)c4C)c(OC)c3)c2cc1OC,3.29 | |
| CCNc1nc(Nc2ccccc2)nc(n1)C#N,3.11 | |
| O=C1CCOc2nc(\C=C\c3ccccc3)ccc12,3.2 | |
| COc1cc2ncnc(Nc3cc(NC(=O)c4ccnc(c4)N5CCOCC5)ccc3C)c2cc1OCCN6CCCC6,2.7 | |
| NS(=O)(=O)c1cc2c(NC(Cc3ccccc3)NS2(=O)=O)cc1C(F)(F)F,1.78 | |
| C(CNCc1ccccc1)NCc2ccccc2,.73 | |
| CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2,1.96 | |
| Cc1cc(Oc2ccc3OCOc3c2)nc(Oc4ccc(cc4)n5ccnc5)n1,3.47 | |
| CS(=O)(=O)Cc1cc(nc(n1)c2cnc3[nH]ccc3c2)N4CCOCC4,1.92 | |
| COC(=O)CCCC(=O)Nc1ccc2C(=O)C(=O)c3ccccc3c2c1,2.96 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccncc3C#N)cn2)c4noc(n4)C5CC5,3.1 | |
| CCN(CC)S(=O)(=O)c1ccc(cc1)c2oc(SCC(=O)N3CCc4ccccc34)nn2,3.9 | |
| OC(=O)C[C@H]1[C@@H](Cc2ccccc12)NC(=O)c3cc4sc(Cl)c(Cl)c4[nH]3,2.53 | |
| Cc1ccc(cc1NC(=O)c2cnn(c2N)c3ccccc3F)C(=O)Nc4ccon4,2.6 | |
| CN1CCN(CC1)c2cc(F)cc3C(=O)C=C(Nc23)C(=O)Nc4ccc(cc4)N5CCOCC5,2.7 | |
| CC(C)Oc1cc(OCCc2cccnc2)cc(c1)C(=O)Nc3ccc(cn3)C(=O)O,.81 | |
| Cn1c(nc2ccccc12)c3ccc(O)nc3,1.2 | |
| CCOC(=O)C1(CCCN(CC2CC2)C1)c3cccc(O)c3,1.89 | |
| OCCCn1c(NC(=O)c2cccc(c2)[N+](=O)[O-])nc3ccccc13,3 | |
| CCC(CC)NC(=O)c1cnn(c1NS(=O)(=O)c2ccc(C)cc2)c3ccccc3Cl,.65 | |
| Clc1ccc2C(=O)C3=C(Nc2c1)C(=O)NN(Cc4ccsc4)C3=O,1.11 | |
| Cc1cc2cc(C)c3nnc(SCC(=O)N4CCN(CC4)C(=O)c5occc5)n3c2cc1C,2.8 | |
| Cc1cc(NC(=O)Nc2ccc(Cl)cc2)n(C)n1,2.96 | |
| CC1(C)N(Cc2ccnc(c2)N3CCOCC3)C(=O)N(C1=O)c4ccc(SC(F)(F)F)cc4,3.73 | |
| CN(C)CC(O)COc1ccc(Nc2cc(Nc3cc(C)ccc3Cl)ncn2)cc1,2.16 | |
| CN(C)S(=O)(=O)c1ccc2C(=CNC(=O)c2c1)C(=O)NC[C@@H](O)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,3.13 | |
| C[C@@H](Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)C(=O)N(C)C,3.67 | |
| CC(CN(C)C)CN1c2ccccc2CCc3ccccc13,2.95 | |
| CC(C)n1ncc2c(cc(nc12)C3CC3)C(=O)NCc4c(C)cc(C)nc4O,3.8 | |
| Cc1cc(Cl)ccc1OC2CCN(C[C@H](O)CNC(=O)c3c[nH]nc3C(F)(F)F)CC2,3.02 | |
| Clc1ccc(NS(=O)(=O)c2ccc(Cl)s2)c(c1)C(=O)Nc3ccc(cc3)S(=O)(=O)N4CCOCC4,3.02 | |
| CN(C)CC(O)COc1ccc(Nc2cc(ncn2)N(CC#N)c3cc(Cl)ccc3Cl)cc1,2.1 | |
| CCN1CCC[C@H]1CNC(=O)c2c(OC)ccc(Br)c2OC,.05 | |
| C[C@@H](CNC(=O)c1c(O)c(O)cc2c(O)c(c(C)cc12)c3c(C)cc4c(C(=O)NC[C@H](C)c5ccccc5)c(O)c(O)cc4c3O)c6ccccc6,3.48 | |
| COc1ccc(cc1C(=O)N)c2ccc3c(nc(nc3n2)N4CCOC[C@@H]4C)N5CCOC[C@@H]5C,2.82 | |
| Oc1cc(ccc1NC(=O)Nc2ccccc2Br)[N+](=O)[O-],3.9 | |
| COc1ccc(cc1)S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,1.39 | |
| C[C@H](CN(C)C(=O)CO)Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12,3.22 | |
| Clc1ccc(O[C@H]2CCCNC2)cc1C(=O)NCC34CC5CC(CC(C5)C3)C4,2.18 | |
| COCCS(=O)(=O)N1CCN(CC1)c2ccc(Nc3nccc(n3)c4cnc(C)n4C(C)C)cc2,2.75 | |
| Oc1ccc(cc1)C2=CC(=O)c3ccc(O)cc3O2,3.2 | |
| Cc1cccc(Nc2ccccc2C(=O)O)c1C,1.89 | |
| CCCc1c(O)c(ccc1OCc2ccc(C(=O)O)c(Br)c2)C(=O)C,2.3 | |
| CC1CCC(CC(=O)Nc2cccc3ncccc23)CC1,3.56 | |
| CCCN[C@H]1CCc2nc(N)sc2C1,3.15 | |
| Nc1nc(OCc2nccs2)nc3c1ncn3[C@@H]4O[C@H](CF)[C@@H](O)[C@H]4O,.47 | |
| CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c3cc(OC)ccc3n4c(C)nnc14,2.46 | |
| Nc1ccccc1NC(=O)c2ccc(cc2)c3ncc(CN4CCC4)cc3F,1.69 | |
| O=C(N1CCN(CC1)c2ncccn2)c3cccc(CC4=NNC(=O)c5ccccc45)c3,2.13 | |
| O[C@@H](CNCCCSCCNCCc1ccccc1Cl)c2ccc(O)c3NC(=O)Sc23,.99 | |
| Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1NC(=O)c3ccc4ncccc4c3,3.87 | |
| c1ccc(cc1)c2nnc(s2)c3ccccc3,4.2 | |
| CC(C)(C)NCC(O)COc1nsnc1N2CCOCC2,-.35 | |
| Cc1ccc(cc1)S(=O)(=O)Nc2c(cnn2c3ccccc3)C(=O)NCc4ccccc4,1.9 | |
| CN1CCCC(CN2CCN(CC2)C(=O)Nc3ccc(Cl)c(Cl)c3)C1,1.98 | |
| CCCCN(CCNC[C@H](O)c1ccc(O)c2NC(=O)Sc12)C(=O)CCOCCc3ccccc3,2.51 | |
| Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)cc4,1.6 | |
| C[C@]1(CCSC(=N1)N)c2cc(c(F)cc2F)c3cncnc3,.8 | |
| CC(C)Oc1cc(n[nH]1)n2cnc3cnc(N[C@@H](C)c4ncc(F)cn4)nc23,2.41 | |
| Nc1[nH]ncc1c2cc(Cl)ccc2Oc3cc(F)c(cc3Cl)S(=O)(=O)Nc4cscn4,2.3 | |
| Cc1cnc(cn1)C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3,.31 | |
| OC(=O)c1ccccc1Cn2nnc(n2)c3cccc(OCc4ccc5ccccc5n4)c3,2.1 | |
| Clc1ccc(cc1)C(=O)C2CCN(CC2)C(=O)C3CC3,2.72 | |
| COCCNCc1cccc(CCNC[C@H](O)c2ccc(O)c3NC(=O)Sc23)c1,.01 | |
| COc1cc2ncc(C(=O)N)c(Nc3ccc(F)cc3)c2cc1OC,2.82 | |
| O=C(Nc1cccc(NC(=O)c2ccccc2)n1)c3ccccc3,4.02 | |
| NCC[C@@H](Oc1cc(Cl)ccc1C#N)c2ccccc2,.76 | |
| CCc1[nH]nc(NC(=O)Cc2ncc(Oc3ccnc4cc(OC)c(OC)cc34)cc2OC)c1C,2.79 | |
| CN(C)CC(O)COc1ccc(Nc2cc(ncn2)N(CC#C)c3cc(Cl)ccc3Cl)cc1,2.8 | |
| Nc1ccc2ncccc2c1,1.33 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2CCN(CCc3ccccc3)C2,1.65 | |
| Cc1c(Sc2ccc(Cl)cc2)c3c(Cl)nccc3n1CC(=O)O,.92 | |
| Brc1ccc2OCC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,1.42 | |
| CC(C)N1CCN(Cc2cnc(c(Cl)c2)c3ccc(cc3)C(=O)Nc4ccccc4N)CC1,1.68 | |
| CC(C)CNc1nc(nc(N2CCNCC2)c1N)C#N,.7 | |
| C[C@@H](O)[C@H](NC(=O)c1ccc(cc1)C#Cc2ccc(CN3CCOCC3)cc2)C(=O)NO,2.03 | |
| O[C@H](CNC(=O)N1C(=O)Nc2ccccc12)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,4.46 | |
| Cc1c(Oc2ccc(Cl)cc2)c3cc(ccc3n1CC(=O)O)C(F)(F)F,2.28 | |
| CC(C)(F)C[C@H](N[C@@H](c1ccc(cc1)c2ccc(cc2)S(=O)(=O)C)C(F)(F)F)C(=O)NC3(CC3)C#N,2.9 | |
| CN(C)CCCN1c2ccccc2CCc3ccccc13,2.49 | |
| CN1CCOc2cc(COC3CCCCC3)cnc12,3.1 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)CN3CCOCC3)C(=O)C(F)(F)F,2 | |
| COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC,2.61 | |
| COc1ccccc1Nc2cc(Oc3cc(C)c(C)nc3c4ccccn4)ccn2,3.37 | |
| Fc1cc(C(=O)Nc2cccc(c2)c3nnn[nH]3)c4nc[nH]c4c1,.29 | |
| Clc1cccc(c1)N2CCN(CCCN3N=C4C=CC=CN4C3=O)CC2,2.67 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3ccccc3C(F)(F)F)c2C(=O)N4CC[C@@H](O)C4,2.74 | |
| CC(=O)c1ncccc1NC(=O)[C@@H]2CC[C@H](CC2)N3C(=O)[C@@H]4[C@@H]5CC[C@@H](C5)[C@@H]4C3=O,3.01 | |
| CC(=O)Nc1ccc2nc(cc(O)c2c1)c3cccc(F)c3,2.41 | |
| COc1ccc2nc(N[C@H]3CCC[C@@H](C3)NCc4ccsc4)cc(C)c2c1,2.41 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4c(F)cccn34)N5CCN(CC5)C(=O)C,3.5 | |
| CC(C)NCC(O)COc1ccccc1OCC=C,.2 | |
| COc1ccc2N=CC(=O)N(CCN3CCC(CC3)NCc4cc5OCCOc5cn4)c2n1,.83 | |
| O=C(N1CCCCC1)c2scc3CCCCc23,3.16 | |
| NC(=O)Nc1sc(cc1C(=O)N)c2ccc(OCCN3CCCCC3)cc2,1.2 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CN=C1c2cccs2)NC(=O)OCc3ccccc3)C(=O)C(F)(F)F,2.02 | |
| CS(=O)(=O)c1ccc2nc(sc2c1)N3CCN(CC3)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,1.49 | |
| Oc1ccc(cc1)C2CNCCc3c(Cl)c(O)c(O)cc23,.87 | |
| CS(=O)(=O)c1cccc(Nc2nccc(Nc3c(Cl)ccc4OCOc34)n2)c1,3.13 | |
| CCS(=O)(=O)c1ccc2OCC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,-.11 | |
| COc1ccc(OC)c(c1)c2cccc3c(N)c(nnc23)C(=O)NC(C)C,3.65 | |
| O=C1C=C(Oc2c1cccc2c3cccc(c3)c4ccsc4)N5CCOCC5,4.2 | |
| CC(C)(C)c1cc2nc3C(=O)N(Cc4ccccc4)Cc3c(O)n2n1,1.9 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccccc3)n2,3.58 | |
| [O-]c1c2c(nn1c3ccc(Cl)cc3)c4ccccc4c[n+]2Cc5ccccc5,4.5 | |
| O=C(NC1(CC1)C#N)[C@@H]2CCCC[C@H]2C(=O)N3CCc4oc5ccccc5c4C3,3.01 | |
| COc1ccc(CNC(=O)Nc2ncc(s2)[N+](=O)[O-])cc1,2.9 | |
| Oc1cc(O)c2C(=O)C(=COc2c1)c3ccc(O)c(O)c3,2.45 | |
| CO[C@@H]1CC[C@@]2(CC1)Cc3ccc(cc3C24N=C(C)C(=N4)N)c5cncc(Br)c5,3.4 | |
| O[C@@H](CNCCc1cccc(CN2CCCC2)c1)c3ccc(O)c4NC(=O)Sc34,-.28 | |
| COc1ccc(cc1)C2=C(C)c3ccc(OC)cc3OC2=O,3.31 | |
| CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)\C(=N/OCOCCOC)\[C@H](C)[C@@H](O)[C@]1(C)O,1.8 | |
| COc1cc2ncc(C(=O)N)c(Nc3ccc(F)cc3F)c2cc1OC,2.95 | |
| CC(C)(C)OC(=O)N1CCN(CC1)c2ncc(OCc3ccncc3)cn2,3.4 | |
| CC(C)C[C@H](CO)Nc1nc(SCc2ccccc2F)nc3nc(N)sc13,4.5 | |
| CNC(=O)[C@H]1CCCN1Cc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC,3.65 | |
| CCn1nc(C)c(C(=O)N[C@@H](C)C(C)(C)C)c1NS(=O)(=O)c2ccc(C)cc2,.95 | |
| Cc1ccc(O)c(O)c1,1.37 | |
| CCc1c2CN3C(=O)C4=C(C=C3c2nc5ccc(O)cc15)[C@@](O)(CC)C(=O)OC4,1.6 | |
| COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN4CCCCC4,4.1 | |
| Nc1n[nH]cc1c2cc(ccc2Oc3cc(F)c(cc3Cl)S(=O)(=O)Nc4cscn4)C(F)(F)F,2.65 | |
| Fc1ccc(cc1C#N)S(=O)(=O)NCC(N2CCCCCC2)c3ccccc3,2.71 | |
| CC(=O)Nc1ccc2ccn(c3cc(NC4COC4)n5ncc(C#N)c5n3)c2c1,2.24 | |
| CCNC(=O)C[C@H]1N=C(c2ccc(Cl)cc2)c3cc(OC)ccc3n4c(C)nnc14,2.42 | |
| COc1ccc(cc1)S(=O)(=O)NCC(N2CCCCCC2)c3ccccc3,3.13 | |
| Cc1ncc(CO)c(CO)c1O,-.58 | |
| NC(=O)Nc1sc(cc1C(=O)N)c2ccc(CNC3CCCC3)cc2,1.22 | |
| CCCSc1nc2ccc(NC(=O)CCC(=O)O)cc2s1,.5 | |
| CS(=O)(=O)Nc1ccc(CCOCCCS(=O)(=O)CCNCCc2ccc(O)c3nc(O)sc23)cc1,1.34 | |
| Cc1cccc(c1)S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,1.84 | |
| C[C@@H]1CN(CCN1C(=O)[C@@H]2CCCC[C@H]2C(=O)NC3(CC3)C#N)c4ccc5c(C)nnc(C)c5c4,1.93 | |
| CC(=O)Nc1ccc2CCN(c3cc(NC4CC4)n5ncc(C#N)c5n3)c2c1,3.3 | |
| Fc1cc(F)cc(c1)c2cc(on2)N(CCCN3CCCCCC3)Cc4ccc5OCOc5c4,3.84 | |
| COc1ccc2nc(C)cc(N3CC(CNC(=O)C4CC4)OC3=O)c2c1,1.55 | |
| CC(C)c1ccccc1Nc2nc(SCc3cccs3)n[nH]2,4.21 | |
| Nc1nc2ccc(F)cc2s1,2.2 | |
| COc1cc(N2CC[C@H](C2)N(C)C)c3NC(=CC(=O)c3c1)C(=O)Nc4ccc(cc4)N5CCOCC5,2.7 | |
| Oc1ccc(cc1)S(=O)(=O)Nc2nccs2,.36 | |
| Clc1cccc(Nc2ncnc3ccccc23)c1,3.9 | |
| O=C(N1CCCC1)c2ccc(cc2)C(=C3CCN(Cc4cscn4)CC3)c5cccc6cccnc56,2.75 | |
| NC(=O)c1cnc(N[C@H]2CCCNC2)c3cc(sc13)c4ccc(F)c(Cl)c4,2.94 | |
| O=C(NC1CCCC1)C(N(Cc2occc2)C(=O)c3ccc([nH]3)c4ccccc4)c5ccncc5,4.36 | |
| CN1C(=N)N(CC(=O)c2ccc(Cl)cc2)c3ccccc13,1.63 | |
| CN1CCN(CC1)C(=O)c2cc3cc(Br)ccc3[nH]2,2.79 | |
| COc1cccc(c1)C(=O)N2CCC(CC2)N3C(=O)Nc4ccccc34,2.65 | |
| CCCS(=O)(=O)N1CCCC(C1)C(=O)N2CCC(Cc3ccccc3)CC2,3.44 | |
| COC1(CCOCC1)c2ccc(NC(=O)C3=CC(=O)c4cc(F)cc(c4O3)c5c(C)nn(C)c5C)cn2,2.98 | |
| CNC(=O)c1ccc(CCC(COc2ccc(cc2)c3cccc(c3)[N+](=O)[O-])N4C(=O)CSC4=O)cc1,3.5 | |
| CN1CCCC1c2cccnc2,.5 | |
| Oc1nc2cc(Cl)cc(Cl)c2c(O)c1c3ccccc3,1.6 | |
| CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc3cnccn3,.9 | |
| Oc1ccc(cc1)C2CC(=O)c3ccc(O)cc3O2,2.4 | |
| NCc1nc2ccccc2[nH]1,.4 | |
| OC(=O)c1cc(nc2ccc(F)cc12)c3ccncc3,-.8 | |
| Nc1nccc(n1)c2ccccc2,2 | |
| OCCN1CC=CC[C@@H](C1)c2ccc(Cl)c(Cl)c2,2.37 | |
| CN(c1ccnc(Nc2cc(cc(c2)N3CCOCC3)N4CCCCC4)n1)c5cc(CO)ccc5C,4.2 | |
| Oc1ccc(cc1)c2cnc3ccccc3n2,3.3 | |
| COc1ccc2[nH]c3CCN(Cc3c2c1)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,2.4 | |
| CC(CCc1cccc(OCc2ccc3ccccc3n2)c1)CC(=O)O,2.4 | |
| FC(F)(F)Oc1ccc(CNC(=O)C2N(CC3CC(F)(F)C3)C(=O)c4ccccc24)cc1,3.9 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3ccccc3C(F)(F)F)c2C(=O)N(C)C,2.9 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2C[C@@H]3CC[C@H]2N(CCc4ccccc4)C3,1.64 | |
| FC(F)(F)c1ccc2[nH]c3CCN(Cc3c2c1)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,4.2 | |
| CCCc1c(OCCCSc2ccc(CC(=O)O)cc2Cl)ccc3c(CC)noc13,3.92 | |
| OC(=O)c1cc(ccc1O)c2ccc(F)cc2F,.59 | |
| CCOc1ccc(Oc2ccc(cc2)S(=O)(=O)NC(=O)c3cccc(c3)c4ccc(Cl)c(Cl)c4)cc1,2.94 | |
| OC1=CC=Cc2cc(O)c(O)c(O)c2C1=O,2.03 | |
| CC1=CN([C@H]2CCCN(C2)S(=O)(=O)c3ccc(O)c(Oc4cc(F)cc(Cl)c4)c3)C(=O)NC1=O,2.35 | |
| O[C@@H](CNCCSCCCNCCc1cccc(c1)C(F)(F)F)c2ccc(O)c3NC(=O)Sc23,1.21 | |
| Cc1c(Sc2ccc(Cl)cc2)c3cc(Cl)ccc3n1CC(=O)O,2.87 | |
| Cc1ccc(cc1NC(=O)c2ccc(OCc3ccccn3)cc2)c4cn(C)c(C)n4,2.71 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)NCc4ccccc4,4 | |
| CN1[C@@H]2CC[C@H]1C[C@H](C2)OC(c3ccccc3)c4ccccc4,1.49 | |
| O[C@@H](CNCCc1cccc(CN2CCC(CC2)c3ccccc3)c1)c4ccc(O)c5NC(=O)Sc45,1.99 | |
| Oc1cccc(c1)N2C(=O)c3ccc(O)cc3C2=O,2 | |
| NS(=O)(=O)c1ccc(NCc2ccccc2)cc1,1.7 | |
| CCCN(c1cccnc1)P(=O)(c2ccccc2)c3ccccc3,2.6 | |
| CC1(C)[C@@H]2CC[C@@]1(CS(=O)(=O)NC3CCN(CC3)c4ccc(cn4)C(F)(F)F)C(=O)C2,3.84 | |
| FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)C(=O)NCC2CCCCN2,1.13 | |
| CN1CC=CCC(C1)c2oc3ccccc3c2,2.47 | |
| CCN(C1CCN(CCC(c2ccc(NC(=O)C)cc2)c3cccc(F)c3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,2.41 | |
| CC(=O)Nc1ccc2ccn(c3cc(Nc4ccn(C)n4)n5ncc(C#N)c5n3)c2c1,3.57 | |
| COc1ccc(cc1F)c2cc(nn2c3ccc(cc3)S(=O)(=O)N)C(F)F,2.8 | |
| O=C(Nc1nnn[nH]1)C2=CC(=C3C=CC=CN3C2=O)Oc4ccccc4,.67 | |
| COc1cccc2c(O)cc(nc12)c3ccccc3,2.3 | |
| Cc1onc(n1)c2ccc(OCC3CN(C3)c4ccc(C)nn4)cc2,2.62 | |
| C(N(Cc1ccccc1)c2nn[nH]n2)c3ccccc3,1.37 | |
| CN1CCN(CC1)c2nc(CCOc3ccc(C[C@H](Nc4ccccc4C(=O)c5ccccc5)C(=O)O)cc3)c(C)s2,2.58 | |
| CC(=O)c1ccc(nc1)N2CCN(CC2)S(=O)(=O)C[C@]34CC[C@H](CC3=O)C4(C)C,2.21 | |
| Clc1cccc(CN2C=CN3C(=O)C=C(N=C23)N4CCOCC4)c1Cl,3.3 | |
| C[C@@H](NC1=CC(=O)NCC1)c2ccc(Nc3ncc4cc(ccc4n3)c5ccncc5)cc2,3.02 | |
| C[C@H]1CN(Cc2cc(Cl)ccc2CCC(=O)O)CCN1C(=O)Cc3ccccc3,1.52 | |
| Clc1cccc(\C=C\2/SC(=O)NC2=O)c1N3CCNCC3,.68 | |
| CSc1nc(nn1Cc2ccccc2)c3ccccc3,3.83 | |
| Nc1ccc2c3ccccc3C(=O)C(=O)c2c1,2.23 | |
| Nc1ccccc1NC(=O)c2ccc(cc2)C3CCN(CCC(=O)Nc4ccccc4F)CC3,2.76 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)N4CCOCC4)n2,2.88 | |
| CN(c1ccnc(Nc2cc(CN3CCOCC3)cc(c2)N4CCOCC4)n1)c5cc(CO)ccc5C,3 | |
| NC(=O)c1cc(O)cc2nc(oc12)c3ccc(O)cc3,2.3 | |
| COc1ccc(N(C(C(=O)NC2CCCC2)c3ccccc3F)C(=O)c4occc4)c(OC)c1,3.09 | |
| C[C@H](C1=CNC(=S)N1)c2cccc(C)c2C,2.9 | |
| CC[C@H](NC(=O)c1c([S+](C)[O-])c(nc2cc(F)ccc12)c3ccccc3)c4ccccc4,3.62 | |
| CCc1ccccc1c2ccc(cc2)c3nc4ccncc4c(O)c3C#N,3.5 | |
| CN(C)CCOc1cc(NS(=O)(=O)c2c(Cl)cc(cc2Cl)C(F)(F)F)ccc1Cl,2.99 | |
| Oc1ccc(cc1)C2=Cc3ccc(O)cc3OC2=O,2.9 | |
| COc1cc(C)c(c(C)c1)S(=O)(=O)N(C)CCOCC(=O)N2CCN(CC2)C3CCN(C)CC3,-.4 | |
| CC(C)(C)c1cc(O)n2nc(N)nc2n1,-.2 | |
| COc1ccc(cc1)c2cc(O)c3cc(Cl)ccc3n2,2.7 | |
| Oc1ccc(cc1)c2csc(n2)c3ccc(O)cc3,3.7 | |
| C[C@]12Cc3cnn(c3C=C1CC[C@@]2(O)CCc4ccc(F)cc4C(=O)N)c5ccc(F)cc5,3.8 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4cc(ccn34)N5CCCC5)N6CCN(CC6)C(=O)C,3.5 | |
| Cc1ccc2[nH]ccc2c1c3nc(cc(n3)C4(CC4)S(=O)(=O)C)N5CCOCC5,1.7 | |
| Nc1ccc(Cl)c(c1)C(=O)NCC23CC4CC(CC(C4)C2)C3,3.45 | |
| O=C(Nc1cccc2cccnc12)c3ccc(cc3)N4C(=O)[C@@H]5[C@H]6C[C@H](C=C6)[C@@H]5C4=O,3.28 | |
| CCCCSc1nc(N)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1,1.51 | |
| Oc1ccc(cc1)c2ccc3cc(O)ccc3c2,4 | |
| Nc1cc(nc2c(cnn12)C#N)c3cccs3,2.3 | |
| CCC(N(CCCN)C(=O)c1ccc(OC)cc1)C2=Nc3ccsc3C(=O)N2Cc4ccccc4,1.39 | |
| Cc1cc(N)c2cc(NC(=O)CCCCC(=O)Nc3ccc4nc(C)cc(N)c4c3)ccc2n1,.53 | |
| CN(C)CC(O)COc1ccc(Nc2cc(ncn2)N(CC#N)c3ccc(C)cc3Br)cc1,2.24 | |
| NC(=O)C1=CN(Cc2ccc(F)c(F)c2)C(=O)C=C1,1.37 | |
| COc1ccc(c(C)n1)c2cccc3c(N)c4C(=O)N(Cc4nc23)C5CCC5,3.92 | |
| OC(=O)c1ccc(cc1)c2ccc(Cl)c(c2)C(=O)NCC34CC5CC(CC(C5)C3)C4,2.48 | |
| COc1cc2c(Nc3ncc(CC(=O)Nc4cccc(F)c4)s3)ncnc2cc1OCCCN5CCC(CO)CC5,2.89 | |
| C[C@H]1CN(Cc2cc(Cl)ccc2OC(C)(C)C(=O)O)CCN1S(=O)(=O)c3ccccc3,.54 | |
| CCCSc1nc(NC[C@@H]2CC[C@H](CC2)C(=O)O)ccc1C(=O)NC3CCCCC3,2.61 | |
| Cc1ccccc1CN2C=CN3C(=O)C=C(N=C23)N4CCOCC4,2.3 | |
| CNC(=O)c1c(F)cccc1Nc2nc(Nc3cc4N(CCc4cc3OC)C(=O)CN(C)C)nc5[nH]ccc25,2.61 | |
| O[C@]1(CN2CCC1CC2)C#Cc3ccc(Oc4ccc(cc4)C(=O)NC5CCCS(=O)(=O)C5)cc3,1.4 | |
| CCCCN(CCCC)CCCOC(=O)c1ccc(N)cc1,1.93 | |
| OC(=O)C(N1CCC(CN2CCC(CC2)Oc3ccc(Cl)c(Cl)c3)CC1)c4ccccc4,2.17 | |
| OCC[C@]1(CCCNC1)c2oc3ccccc3c2,.06 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3ccccc3C(F)(F)F)c2C(=O)N4CC(C)(O)C4,3.18 | |
| Oc1ccc2OC(=O)C(=Cc2c1)c3ccccc3,3.12 | |
| CN(C1CCN(Cc2ccc(cn2)C(F)(F)F)CC1)C(=O)Cc3ccc(cc3)n4cnnn4,1.9 | |
| Nc1n[nH]c(Nc2ccccc2)n1,1.06 | |
| CN(C)S(=O)(=O)c1ccc2Sc3ccccc3\C(=C\CCN4CCN(C)CC4)\c2c1,3.16 | |
| CN(c1ccnc(Nc2cc(cc(c2)N3CCN(C)CC3)N4CCOCC4)n1)c5cc(CO)ccc5C,2.61 | |
| CN(C)CC(O)COc1ccc(Nc2nccc(Nc3ccccc3C#N)n2)cc1,1.2 | |
| Oc1c(I)cc(I)c2cccnc12,2.19 | |
| Clc1ccc2C(=O)C3=C(Nc2c1)C(=O)NN(CC#Cc4ccccc4)C3=O,1.78 | |
| O[C@@H](CNCCc1ccc(CNCCc2ccccc2F)cc1)c3ccc(O)c4NC(=O)Sc34,1.3 | |
| CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c3ccccc13,3.15 | |
| Cc1cc(COc2cnc(nc2)N3CCN(CC3)C(=O)OC(C)(C)C)ccn1,3.7 | |
| CCCN(C)c1nc(ccc1C(=O)NC2CCCCC2)N3CCC[C@@H](CC(=O)O)C3,2.28 | |
| NC12CCC(CC1)(CC2)c3ccccc3,.29 | |
| COc1cc(ccc1Cn2ccc3ccc(NC(=O)OC4CCCC4)cc23)c5nn[nH]n5,2.7 | |
| CCc1nc2c(N)nc3ccccc3c2n1CCCCNS(=O)(=O)C,1.24 | |
| CNc1nc2ccccc2n1Cc3sc4N(CC(C)C)C(=O)N(C)C(=O)c4c3C(=O)N5CC[C@@H](O)C5,1.61 | |
| CC(C)Oc1ccc(cc1)C(=O)Nc2cc(NC(=O)c3cccc(c3)N(C)C)ccc2C,3.1 | |
| CC(=O)Nc1nnc(s1)S(=O)(=O)N,-.78 | |
| CCC[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1S(=O)(=O)c3ccccc3,1.02 | |
| CN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)Cc4ccc(NC(=O)C)cc4,2.9 | |
| Nc1ncnc2sc(nc12)c3c(ncn3C[C@H]4CCCO4)c5ccccc5,2.65 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CN=C1C2CCCCC2)NC(=O)OCc3ccccc3)C(=O)C(F)(F)F,2.87 | |
| NC1(CCC1)c2ccc(cc2)c3ncc4ncccc4c3c5ccccc5,2 | |
| CC(=O)Nc1ccc2ccn(c3cc(NCCCCO)n4ncc(C#N)c4n3)c2c1,2.58 | |
| COC1=CC(=N/C/1=C\c2[nH]c(C)cc2C)c3cc4ccccc4[nH]3,2.55 | |
| Nc1ccccc1NC(=O)c2ccc(cc2)N3CCOCC3,1.2 | |
| CCC(CCNC)Oc1cc(Cl)ccc1C#N,.38 | |
| O=C(Nc1ccccc1)c2oc3ccccc3c2,3.44 | |
| COc1cc2ncnc(Nc3ccc(OCc4ccccn4)c(C)c3)c2cc1OC,3.6 | |
| COCCC(=O)N[C@H](C)c1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,3.08 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CN=C1c2ccc(F)cc2)NC(=O)OCc3ccncc3)C(=O)C(F)(F)F,2.22 | |
| COc1cc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)ncnc2cc1OCCCN5CCC(CO)CC5,2.11 | |
| Cc1ccc2c(c1)c(c(C)n2CC(=O)O)c3ccnc4c(F)cccc34,.53 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2CCN(C2)C(=O)Cc3ccccc3,.81 | |
| CCC(C)NC(=O)c1c(C)nn(c1NS(=O)(=O)c2ccc(C)cc2)c3ccccc3,.66 | |
| CN(C)c1ccc(cc1)S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(C)c4Cl,2 | |
| COc1ccc2c(c1)c(CC(=O)O)c(C)n2c3ccnc4cc(Cl)ccc34,1.68 | |
| NC(=N)Nc1cc(Cl)nc(n1)c2ccccc2,2.16 | |
| COc1cccc(Nc2oc(nn2)C(=O)Nc3ccc(nc3)N4CCOCC4)c1,2.8 | |
| CC(C)Oc1cc(OCCCN2CCCC2)cc3ncnc(Nc4c(Cl)ccc5OCOc45)c13,3.1 | |
| CCN(CC)CCOc1ccc(cc1OC)N(C)C(=O)c2ccc(cc2)c3ccc(cc3)C(F)(F)F,3.13 | |
| C[C@H](NC(=O)c1c(C)nn(c1NS(=O)(=O)c2ccc(C)cc2)C(C)(C)C)C(C)(C)C,1.84 | |
| Cc1ccc2c(c1)c(c(C)n2CC(=O)O)c3ccnc4c(Cl)cccc34,1.27 | |
| COc1ccc(cc1)C(=O)C2CCN(CC2)C(=O)c3occc3,2.42 | |
| COc1cc(Nc2ncnc3cccc(O[C@H](C)C(=O)N4CCOCC4)c23)ccc1Oc5ccc(C)nc5,3.6 | |
| COc1ccc(C=NN=Cc2ccc(OC)c(OC)c2)cc1OC,3.38 | |
| CS(=O)(=O)c1ccccc1C(=O)NCC(O)CNC2CCN(Cc3ccc(Cl)c(Cl)c3)CC2,1.21 | |
| CN(C1CCN(Cc2nc3CCCCc3s2)CC1)C(=O)Cc4ccc(cc4)n5cnnn5,2.5 | |
| C[C@H](Oc1ccc(Cl)cc1CN2CCN([C@@H](C)C2)C(=O)Cc3ccc(Cl)cc3)C(=O)O,1.66 | |
| CN1SC(=NC1=O)NCc2ccccc2,1.2 | |
| CC(C)N1CCC[C@H](CN2C(=Nc3ccc(cc3C2=O)c4ccc(Cl)cc4)C)C1,3.3 | |
| Clc1ccc2[nH]c3CCN(Cc3c2c1)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,3.65 | |
| COc1cccc(CNCc2cccc(CCNC[C@H](O)c3ccc(O)c4NC(=O)Sc34)c2)c1,.91 | |
| Nc1ncc2cc(c(N)nc2n1)c3c(Br)cccc3Br,2.06 | |
| OC(=O)c1cccc(CN2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2)c1,1.26 | |
| Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCc3ccccc3,3.41 | |
| C[C@H]1CN(CCN1c2ncc(OCc3ccc(cc3)S(=O)(=O)C)cn2)C(=O)OC(C)(C)C,3.5 | |
| CN1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c3C1=O)c6ncnn6C,3.8 | |
| CCN(CC)c1ccc(cc1)c2nn3c(nnc3s2)c4[nH]nc5CCCc45,3.37 | |
| Nc1ncnc2sccc12,1.19 | |
| CC(O)(C(=O)Nc1ccc2c(c1)c3ccccc3S2(=O)=O)C(F)(F)F,3 | |
| CC(C)(C(=O)O)c1ccc(cc1)C(O)CCCN2CCC(CC2)C(O)(c3ccccc3)c4ccccc4,.42 | |
| Nc1c(nnc2c(c(F)ccc12)c3ncccn3)C(=O)NC4CC4,1.59 | |
| NC(=N)NCCC[C@H](NC(=O)COCC(c1ccccc1)c2ccccc2)C(=O)O,.18 | |
| OC[C@H](O)C(=O)N1CCC(=CC1)c2ccc(cc2F)N3C[C@H](COc4ccon4)OC3=O,1.09 | |
| Cc1nc(C)c(nc1C(=O)N)c2ccc3c(CC[C@@]34CC[C@@H](CC4)C(=O)O)c2,1.2 | |
| COc1c2OC(=O)C=Cc2cc3ccoc13,1.97 | |
| CC(C)CNCc1ccc(cc1)c2ccccc2S(=O)(=O)N3CCCC3,1.9 | |
| Fc1cc(Cl)ccc1N2CCN(CC2)C(=O)COCc3ccncc3,2.55 | |
| OCCNCc1cc(Br)ccc1OCc2ccc(Cl)cc2,2.98 | |
| FC(F)Oc1ccc(cc1OCC2CC2)C(=O)Nc3c(Cl)cncc3Cl,3.95 | |
| Cc1cccc(C(=O)N)c1NC(=O)c2ccccc2,1.09 | |
| Cc1nnc(N)s1,-.4 | |
| Cc1cc(Cl)ccc1OC2CCN(C[C@H](O)CNC(=O)C3=CNC(=O)c4c(F)cccc34)CC2,3 | |
| NC(=N)c1ccc(cc1)C(=O)N2CCN(CC2)S(=O)(=O)c3ccc4cc(Br)ccc4c3,.36 | |
| CC(N1NC(=O)c2nc3cc(Cl)ccc3c(O)c2C1=O)c4ccccn4,.51 | |
| C1Oc2ccc(Oc3ccnc(Oc4ccc(cc4)n5ccnc5)n3)cc2O1,3.27 | |
| CC(C)Oc1cc(Oc2ccc(cc2)S(=O)(=O)C)cc(c1)C(=O)Nc3nccs3,3.61 | |
| NS(=O)(=O)c1ccc(CCNc2ccc3nnc(c4ccccc4)n3n2)cc1,2.19 | |
| C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc4C(=O)C(=CN1c24)C(=O)O,-.35 | |
| CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1,2.8 | |
| CC[C@H](NC(=O)c1c(N)c(nc2ccccc12)c3cccc(F)c3)c4ccccc4,4.05 | |
| COc1cc2c(Nc3ccc(F)cc3F)c(cnc2cc1N4CCN(C)CC4)C(=O)N,1.75 | |
| CNC(=O)c1ccc(Oc2ccc(cc2)C#C[C@]3(O)CN4CCC3CC4)cc1,1.99 | |
| Nc1c(NC2CCOC2)nc(nc1N3CCOCC3)C#N,1.6 | |
| CN1C(=O)C=C(CCc2ccccc2)N=C1N,2 | |
| CS(=O)(=O)N1CCN(Cc2cc3nc(nc(N4CCOCC4)c3s2)c5cccc6[nH]ncc56)CC1,3.3 | |
| CC1(C)Oc2ncnc(N)c2N=C1c3ccc(cc3)[C@@H]4CC[C@@H](CC(=O)O)CC4,1.32 | |
| CN(C)c1ccc(cc1)S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,1.7 | |
| COCCC(=O)Nc1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,2.78 | |
| Cc1cc(OC2CCN(CC3CCN(CC3)[C@@H](Cc4ccc(F)cc4)C(=O)O)CC2)ccc1Cl,2.54 | |
| COc1cc2ncnc(Nc3ccc(Cl)c(O)c3)c2cc1OC,3.3 | |
| CS(=O)(=O)NCCC(NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4ccc(Cl)cc4,2.2 | |
| CS(=O)(=O)N1CCc2c1nc(nc2c3cnc(N)nc3)N4CCOCC4,1.2 | |
| Nc1nc(N)c2cc(NCc3ccc(Cl)c(Cl)c3)ccc2n1,2.22 | |
| Cc1c(Sc2ccc(Cl)cc2)c3ccc(cc3n1CC(=O)O)S(=O)(=O)C,.79 | |
| COc1cc(c(OC)nn1)c2c(F)ccc3c(N)c(nnc23)C(=O)NC4CC4,2.75 | |
| CN1CCN(CC1)c2ccc3ncc(C(=O)N)c(Nc4ccc(F)cc4F)c3c2,2.3 | |
| CCn1c(C)ncc1c2ccnc(Nc3ccc(cc3)C(=O)NC)n2,2.53 | |
| OC1(CCN(Cc2c[nH]c3ccccc23)CC1)c4ccc(Cl)cc4,2.25 | |
| CCCc1cc(Nc2nc(NCc3onc(C)c3)ncc2Br)n[nH]1,3.63 | |
| CCNCc1cnc(s1)c2ccc(cc2)C(=O)Nc3ccccc3N,.95 | |
| Fc1ccc2[nH]c3CCN(Cc3c2c1)C(=O)[C@@H]4CCCC[C@H]4C(=O)NCC#N,2.77 | |
| Clc1cc(Cl)cc(CS(=O)(=O)NCC(N2CCCCCC2)c3ccccc3)c1,3.23 | |
| CS(=O)(=O)c1ccc(cc1)N2CCN(CC2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NCC#N,.67 | |
| FC(F)(F)c1nnc2ccc(nn12)N3CCN(Cc4ccc(cc4)C#N)CC3,2.9 | |
| COc1ccnc(C[S+]([O-])c2nc3cc(OC(F)F)ccc3[nH]2)c1OC,2 | |
| FC(F)c1nc2ccccc2n1c3nc(nc(n3)N4CCOCC4)N5CCOCC5,3.04 | |
| CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1CCCN(CCc2ccccc2)C1)C(C)(C)C,1.46 | |
| CC1CCN(CC1)C(=O)c2scc3OCCOc23,2.26 | |
| C[C@H](NC1=NC(=O)C(C)(S1)C(F)(F)F)c2ccccc2F,3.1 | |
| COc1ccc(Cl)cc1NC(=O)CCS(=O)(=O)c2ccc(Br)cc2,3.4 | |
| COCCNCc1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,1.86 | |
| Nc1ccc(cc1)S(=O)(=O)N2CCCC2,.98 | |
| CC[C@H](NC(=O)c1c(N)c(nc2ccccc12)c3ccccc3)c4ccccc4,3.89 | |
| O=C(NC1(CC1)C#N)[C@@H]2CCCC[C@H]2C(=O)N3CCN(CC3)c4ccccc4,1.99 | |
| COc1cc2ncnc(N3CC[C@H](C3)Oc4cnc5ccccc5n4)c2cc1OC,4.04 | |
| CCc1csc(n1)N2CCN(CC2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NC4(CC4)C#N,2.1 | |
| Cc1ccc(cc1)n2c(C)cc(C(=O)NS(=O)(=O)c3ccc(C)cc3)c2C,2.5 | |
| O[C@@H](CNCCCCCCCCCN1CCC(CC1)OC(=O)Nc2ccccc2c3ccccc3)c4ccc(O)c5NC(=O)C=Cc45,2.16 | |
| CNc1c(Cl)cnc2[nH]c(nc12)c3ccc(OCCN4CCOCC4)cc3,2.63 | |
| COc1c(N2CCO[C@@H](CN(C)C)C2)c(F)cc3C(=O)C(=CN(C4CC4)c13)C(=O)O,-.62 | |
| O=C(NC1CCCCC1)c2cccnc2Sc3ccccc3,3.01 | |
| C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@H]2O,3.72 | |
| C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CCC2=O,3.4 | |
| CCS(=O)(=O)c1ccc(c(C)c1)c2cc(ccc2OCC(=O)N)C(F)(F)F,2.77 | |
| C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc3nc(NC4CC4)sc13,4.37 | |
| O=C(CSc1ccncc1)Nc2ccc(cc2)C(=O)c3ccccc3,3.6 | |
| Oc1cc(O)c2C(=O)C(=COc2c1)c3ccc(cc3)[N+](=O)[O-],3.24 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3ccccc3C(F)(F)F)c2C(=O)N4CCC4,3.46 | |
| C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C)SC3CN(C3)C4=NCCS4,2.1 | |
| CN1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c6cc(oc6C)C#N)c3C1=O,4.26 | |
| COc1cc2c(NC(=O)Nc3c(Cl)cccc3Cl)ncnc2cc1OCC4CCN(C)CC4,2.7 | |
| Cc1c(c2c(NS(=O)(=O)C)cccc2n1CC(=O)O)S(=O)(=O)c3ccc(Cl)cc3,-.83 | |
| C[C@H](Nc1ccc2ncn(c3cc([nH]n3)C4CC4)c2n1)c5ncc(F)cn5,2.74 | |
| CN(c1ccc(c(C)c1)c2cc(ccc2OCC(=O)O)C(F)(F)F)S(=O)(=O)C,-.59 | |
| CC\C(=C(/c1ccccc1)\c2ccc(\C=C\C(=O)O)cc2)\c3ccccc3,3.89 | |
| CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1CCCN(CCc2ccc(cc2)C(F)(F)F)C1)C(C)(C)C,2.85 | |
| CCCCC1C(=O)N(N(C1=O)c2ccccc2)c3ccccc3,.45 | |
| CC(=O)NC1CC2CCCC(C1)N2C(=O)Nc3ccc(Cl)c(c3)C(F)(F)F,2.79 | |
| COc1c(Nc2ccc(nc2C)S(=O)(=O)C)ncnc1OC3CCN(CC3)C(=O)OC(C)C,2.4 | |
| CC(=O)Nc1ccc(cc1)c2ccnc(Nc3ccc(cc3)N4CCOCC4)n2,2.91 | |
| OC(=O)c1[nH]c2ccccc2c1CCCOc3cccc4ccccc34,2.75 | |
| C[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1C(=O)Cc3ccc(Cl)cc3,1.21 | |
| Cc1nc2nc(nn2c(O)c1Cc3ccccc3)c4cccnc4,1.52 | |
| C[C@H](Nc1nc(Nc2cc(C)[nH]n2)cc(n1)N3CCOCC3)c4ncc(F)cn4,1.91 | |
| COc1ccc(NC(=O)CSc2nnc(C)n2c3ccc(C)cc3)cc1,2.94 | |
| CC1CC(CN)CC(CO)C1,-1.4 | |
| FC(F)(F)c1nnc2ccc(NCc3cccnc3)nn12,2.06 | |
| COc1cc2nnc(C(=O)N)c(Nc3ccc(C)cc3F)c2cc1N4CCN(C)CC4,2.36 | |
| CC(C)c1nc2ccccc2n1c3nc(N4CCOCC4)c5nc(OC6CN(C6)C7CCS(=O)(=O)CC7)n(C)c5n3,2.9 | |
| CCN(CC)CCOC(=O)C1(CCCC1)c2ccccc2,2.3 | |
| OC1(CNCCc2ccccc12)c3ccccc3,1.38 | |
| CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(N3CCOCC3)c(F)c2,.67 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccncc3C#N)cn2)c4ncc(F)cn4,3.4 | |
| Cc1cnc(NC(=O)Cc2ccccc2)s1,2.9 | |
| c1ccc2ncncc2c1,1 | |
| CS(=O)(=O)Cc1cc(nc(n1)c2cccc3cc[nH]c23)N4CCOCC4,2.8 | |
| CC(C)(C)NS(=O)(=O)c1cncc(c1)c2ccc3nc(N)nn3c2,1.41 | |
| O[C@@H](CNCCSCCCOCCc1ccccc1)c2ccc(O)c3NC(=O)Sc23,2.54 | |
| CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12,3.7 | |
| C[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1C(=O)Cc3ccccc3Cl,1.1 | |
| CC[C@@H](NC1=C(Nc2cccc(C(=O)N(C)C)c2O)C(=O)C1=O)c3ccccc3,2.14 | |
| CC1=CC2=NNC(=O)N2c3cc(ccc13)c4ccccc4CO,3.18 | |
| Cc1ccc(NC(=O)c2cccc(c2)N3CCOCC3)cc1NC(=O)c4ccc(OCc5ccccn5)cc4,3.2 | |
| NC1=NC(Nc2c(F)ccc(F)c12)c3occc3,1.2 | |
| CC(C)NC(=O)c1cnc(N2CCC(CC2)N3C(=O)OCc4ccccc34)c(Cl)c1,3.57 | |
| CC(=O)CC(C1=C(O)c2ccccc2OC1=O)c3ccccc3,.86 | |
| CC(C)C(CCCN(C)CCc1ccccc1)(C#N)c2ccccc2,3.6 | |
| Oc1ccc(CCNCCS(=O)(=O)CCCOCCSc2ccccc2)c3sc(O)nc13,2.68 | |
| C[C@@H](O)[C@@H](CO)Nc1nc(SCc2cccc(F)c2F)nc3nc(N)sc13,2.83 | |
| Fc1ccc(cc1)C(=O)C2CCN(CCN3C(=O)Nc4ccccc4C3=O)CC2,2.9 | |
| OC1(CN2CCC1CC2)C#Cc3ccc(Oc4ccc(cc4)C(=O)NCc5ccncc5)cc3,2.48 | |
| CS(=O)(=O)c1ccc2c3CN(CCc3[nH]c2c1)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,1.5 | |
| C[C@@H](NC(=O)C)c1ccc(Nc2ncc3cc(c(C)cc3n2)c4ccncc4)cc1,3.45 | |
| CC[C@H](N1CCC[C@@H](C1)N2C=C(C)C(=O)NC2=O)c3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3,.22 | |
| O=C1Nc2ccccc2C=C1,1.32 | |
| CN(CCO)Cc1ccc(cc1)c2cc(C(=O)N)c(NC(=O)N)s2,.97 | |
| COc1ccc(C=C2SC(=O)NC2=O)cc1OC,1.17 | |
| OC(=O)COc1ccccc1N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,2 | |
| COc1ccc(CNC(=O)c2sc3nc(C)cc(C)c3c2N)cc1,3.85 | |
| CCCc1c(O)c(ccc1OCc2cccc(NC(=O)c3ccccc3C(=O)O)c2)C(=O)C,1.9 | |
| Cc1c(Cl)ccc(OC2CCN(C[C@H](O)CNC(=O)C3=CNC(=O)c4cc(ccc34)S(=O)(=O)C)CC2)c1Cl,2.83 | |
| COc1ccc(cc1)C(=O)C2CCN(CC2)C(=O)c3ccc(F)cc3,2.92 | |
| CC(C)NC[C@@H](C(=O)N1CCN(CC1)c2ncnc3[C@H](O)C[C@@H](C)c23)c4ccc(Cl)cc4,1.3 | |
| CC1=CN([C@H]2CCCN(Cc3ccc(C(=O)O)c(Oc4cccc(Br)c4)c3)C2)C(=O)NC1=O,-.51 | |
| COc1cc(ccc1Cn2ncc3ccc(NC(=O)OC4CCCC4)cc23)C(=O)NS(=O)(=O)c5ccccc5,1.8 | |
| O[C@H](CNC(=O)C1=CNC(=O)c2cc(ccc12)S(=O)(=O)NC3CC3)CN4CCC(CC4)Oc5ccc(Cl)c(Cl)c5,3.67 | |
| CN1CCN(CC1)c2ccc3N=CN(C(=O)c3c2)c4cc(NC(=O)c5ccc(cc5)C#N)ccc4C,2.73 | |
| Fc1cccc2[nH]c3CCN(Cc3c12)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,3.2 | |
| NC1C2CN(CC12)c3nc4N(C=C(C(=O)O)C(=O)c4cc3F)c5ccc(F)cc5F,.3 | |
| [O-][N+](=O)c1ccc2c(c1)nc3CCCCCn23,2.58 | |
| Oc1ccc2OCC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,.52 | |
| CC1(CC1)c2c(cnn2c3ccc(cc3)C(=O)O)C(=O)NC4C5CC6CC(CC4C6)C5,1.11 | |
| COc1ccc2c(C)cc(N[C@H]3CCC[C@@H](C3)NCc4ccsc4)nc2c1,2.46 | |
| OCC[C@@]1(CCCNC1)c2oc3ccccc3c2,.12 | |
| Oc1ccc(cc1)c2nc3ccc(O)cc3s2,3.65 | |
| CC[C@H](NC(=O)c1c([S+](C)[O-])c(nc2cc(CN(C)C)ccc12)c3ccccc3)c4ccccc4,2.75 | |
| CC(=O)c1ccc2NC(=CC(=O)c2c1)c3cccnc3,1.41 | |
| OC(=O)c1cccc(c1)C(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,1.23 | |
| Cc1c(Sc2ccc(Cl)cc2)c3cc(F)ccc3n1CC(=O)O,1.84 | |
| COc1ccc2c(C)cc(N[C@H]3CCC[C@@H](C3)NCc4cccc(OC(F)(F)F)c4)nc2c1,3.61 | |
| COc1cccc(Nc2nc(NCC3CCCO3)c4ccccc4n2)c1,3.9 | |
| CCOc1cc2nnc(C(=O)N)c(Nc3cccc(Cl)c3F)c2cc1N4CCN(C)CC4,1.99 | |
| COc1ccc(cc1OC)C(C)NC(=O)C2(N)CCN(CC2)c3ncnc4[nH]ccc34,1.8 | |
| CN(c1cccc(c1)C(=O)Nc2ccc(C)c(NC(=O)c3ccc4ncccc4c3)c2)S(=O)(=O)C,2.8 | |
| CC(C)[C@H](N(CCCN)C(=O)c1ccc(C)cc1)C2=Nc3cc(Cl)ccc3C(=O)N2Cc4ccccc4,2.88 | |
| Cc1ccsc1CN2NC(=O)C3=C(C2=O)C(=O)c4ccc(Cl)cc4N3,1.15 | |
| CC(=O)N1CCN(CCOc2ccc(cc2)C3CCN(CC3)c4ccc5nnc(n5n4)C(F)(F)F)CC1,3.2 | |
| Cc1cc(C)c2c(N)c(sc2n1)C(=O)NC3CC3,2.53 | |
| CN1C(=O)c2c(onc2c3ccccc3)C=C1c4ccncc4,2.61 | |
| Cc1ccc(Nc2c(F)cccc2Cl)c(CC(=O)O)c1,1.02 | |
| COC(=O)CCC(=O)Nc1ccc2C(=O)C(=O)c3ccccc3c2c1,2.72 | |
| NC(=O)c1cnc(N[C@H]2CCCNC2)c3cc(sc13)c4ccncc4,.77 | |
| Cc1cccc(c1)N(Cc2cc(F)c(F)cc2F)C(=O)O[C@H]3CN4CCC3CC4,2.24 | |
| CCCC(=O)N1CCN(CC1)c2nnc(c3ccccc3)c4ccccc24,3.2 | |
| C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](C)CN1C(=O)c3cc4c(cn(C)c4cc3Cl)C(=O)C(=O)N(C)C,3.6 | |
| O=C1COc2ccc(CNC3CCN(CCN4C(=O)COc5ccc(cc45)C#N)CC3)nc2N1,.23 | |
| CN1SC(=NC1=O)NC(=O)c2ccccc2,1.13 | |
| C[C@H]1[C@@H]2CN(CCN3CCOCC3)CC[C@H]2Cc4[nH]c5ccc(cc5c14)C(F)(F)F,2.87 | |
| CC(C)NCC(O)COc1cccc2[nH]ccc12,-.12 | |
| C[C@H](Nc1ncc(C)c(Nc2cc(C)[nH]n2)n1)c3ncc(F)cn3,1.75 | |
| CN(C)CCNCc1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,1.4 | |
| Cc1ccccc1Nc2ncnc3ccccc23,2.85 | |
| Cn1c(CN2CCN(CC2)c3ccccc3)nc4ccccc14,3.11 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3ccccc3C(F)(F)F)c2C(=O)N4CCCCC4,4.07 | |
| Nc1c(NC2CCCC2)nc(nc1N3CCOCC3)C#N,2.59 | |
| C1CN2C[C@@H](N=C2S1)c3ccccc3,.81 | |
| CCCCOc1nc(N)c2NC(=O)N(Cc3cccc(CC(=O)OC)c3)c2n1,3.76 | |
| CC(C)(C)OC(=O)N1CCN(CC1)c2ccc(OCc3ccc(cc3)S(=O)(=O)C)cc2,3.9 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4ccc(cn34)N(C)C)N5CCN(CC5)C(=O)C,4.1 | |
| Fc1ccc2[nH]c3CCN(Cc3c2c1)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,3 | |
| COc1ccc(NC(=O)c2ccnc(N)n2)cc1,1.72 | |
| O[C@H](CNC(=O)C1=CNC(=O)c2cc(ccc12)S(=O)(=O)N3CCC3)CN4CCC(CC4)Oc5ccc(Cl)c(Cl)c5,3.02 | |
| CC(C)c1ccccc1Cc2cc(C(=O)Nc3ccc(cc3)S(=O)(=O)c4ccccc4C(C)(C)C)c(O)c(O)c2O,3.44 | |
| COc1cccc(c1)c2cc(O)c3cc(NC(=O)C)ccc3n2,2.41 | |
| CCC(CC)C[C@@H](N1CCC[C@@H](C1)N2C=C(C)C(=O)NC2=O)c3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3,1.68 | |
| CN(c1ccnc(Nc2cccc(c2)S(=O)(=O)C)n1)c3cccc4[nH]ncc34,3.21 | |
| O=C(N[C@H]1CN2CCC1CC2)c3ccc(s3)c4ccccn4,.7 | |
| C[C@H](Nc1nc(Nc2cc(C)[nH]n2)c(C)nc1C#N)c3ncc(F)cn3,1.92 | |
| OCCc1cccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)c1,3.83 | |
| COc1cc(F)ccc1c2cncc(CNC(=O)c3ccccc3)c2,3.76 | |
| COc1cc(OC)c(cc1NC(=O)CSc2ccncc2)S(=O)(=O)N3C(C)CCc4ccccc34,2.82 | |
| Cc1cc(Nc2ccccc2)n(CCC#N)n1,2.3 | |
| CNC(=O)c1ccccc1Sc2ccc3c(\C=C\c4ccccn4)n[nH]c3c2,3.8 | |
| COc1cc(OC)nc(n1)N2N=CC(=C(Cl)C2=O)Cl,1.4 | |
| Oc1ccc(CCNCCS(=O)(=O)CCCOCCc2oc3ccccc3c2)c4sc(O)nc14,2.86 | |
| C[C@H](NC(=O)c1c(C)nn(C2CCN(C)CC2)c1NS(=O)(=O)c3ccc(C)cc3)C(C)(C)C,.8 | |
| NC1(CCC1)c2ccc(cc2)c3c(ccn4ncnc34)c5ccccc5,1.7 | |
| CN1CCN(CC1)C(=O)c2cc3ccccc3n2C,1.71 | |
| CN(C)CC(O)COc1ccc(Nc2nccc(Nc3ccc(Cl)cc3)n2)cc1,2.6 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3ccnc4ccccc34)c2C(=O)N5C[C@H](O)CO5,2.14 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4c(OC)cccn34)N5CCN(CC5)C(=O)C,3.5 | |
| CCCSc1c(cnn1c2ccc(cc2)C(=O)O)C(=O)N(C)C3CCCCC3,.59 | |
| O=S(=O)(Cc1cc(nc(n1)c2ccccn2)N3CCOCC3)c4ccccc4,1.34 | |
| CCN(CC)C(=O)N[C@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1,2.73 | |
| CCOC(=O)C1(CCN(C)CC1)c2ccccc2,1.4 | |
| O=C(NC1=CC(=CNC1=O)c2ccncc2)[C@H](Cc3ccccc3)NC4(CC4)c5ccccn5,3.44 | |
| CNC(=O)C[C@H](Nc1ncc(Cl)c(Nc2cc([nH]n2)C3CC3)n1)c4ccc(F)cc4,2.23 | |
| Cc1cc(O[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)cc(c1)C(=O)N,2.08 | |
| Oc1cc(O)cc(\C=C\c2ccc(O)c(O)c2)c1,2.11 | |
| CCCSc1ncccc1C(=O)N(C)[C@@H]2[C@@H]3CC4C[C@H]2C[C@@](O)(C4)C3,2.49 | |
| CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl,.44 | |
| COCCNC(=O)c1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1C,2.78 | |
| Cc1cccc2c3CN(CCc3[nH]c12)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,2.99 | |
| Cc1cc(N)c2cc(NC(=O)CCC(=O)Nc3ccc4nc(C)cc(N)c4c3)ccc2n1,1.39 | |
| COc1cccc2c(ccnc12)c3c(C)n(CC(=O)O)c4ccc(C)cc34,.49 | |
| CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12,.77 | |
| C1CC1Nc2ccc3nnc(c4ccccc4)n3n2,3.15 | |
| CC(=O)NCC(NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4ccc(Cl)cc4,2.4 | |
| CC(=O)N1CCN(CC1)c2ccc(Nc3nccc(n3)c4cnc5ccccn45)cc2,2.82 | |
| Cc1c(Cl)ccc(OC2CCN(C[C@H](O)CNC(=O)c3c[nH]nc3C(F)(F)F)CC2)c1Cl,3.66 | |
| NC1(CCC1)c2ccc(cc2)c3c(ncc4nccn34)c5ccccc5,1.7 | |
| CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12,1.54 | |
| NC1(CCC1)c2ccc(cc2)c3ncc4cccnc4c3c5ccccc5,1.7 | |
| ON=Cc1oc(cc1)[N+](=O)[O-],1.31 | |
| CC(C)OC(=O)C1=CN(Cc2c(F)cccc2F)c3sc(c(CN(C)Cc4ccccc4)c3C1=O)c5ccc(NC(=O)C(C)C)cc5,3.5 | |
| Clc1cccc(C(=O)N2CCN(CC2)c3ccccn3)c1Cl,2.98 | |
| CC(=O)Nc1ccc2[nH]cc(c3cc(NC4CC4)n5ncc(C#N)c5n3)c2c1,2.65 | |
| C1Cc2ncc(c3ccc4OCCOc4c3)n2C1,2.33 | |
| CNC1=Nc2ncccc2C(=NC1c3cccs3)c4occc4,1.85 | |
| Oc1c(C#N)c(nc2ccncc12)c3ccc(cc3)c4ccccc4C(F)(F)F,3.3 | |
| C[Si](C)(C)C#Cc1cn(C[C@H]2CN(C(=O)O2)c3ccc(C4=CCS(=O)(=O)CC4)c(F)c3)nn1,1.26 | |
| C[C@@H](NC(=O)C)c1ccc(Nc2ncc3cc(cc(C)c3n2)c4ccncc4)cc1,3.46 | |
| CN1CCN(CC1)S(=O)(=O)c2ccc(c3cnc(N)c(n3)C(=O)Nc4cccnc4)c(c2)C(F)(F)F,3.25 | |
| CCC(CC)NC(=O)c1cnn(c1NS(=O)(=O)c2ccc(C)cc2)c3ccccc3,.79 | |
| CC(=O)C1=CN(Cc2ccccc2)C(=O)N(Cc3ccc(F)cc3)C1=O,3.2 | |
| Cc1nc(C)c(nc1C(=O)N)c2ccc(cc2)C34CCC(CC3)(CC4)C(=O)O,1.3 | |
| Cc1sc2ncnc(SCC(=O)N3CCN(CC3)C(=O)c4occc4)c2c1C,2.7 | |
| OC(=O)CCCS(=O)(=O)c1cccc(c1)C(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,.66 | |
| CN(C)CC(O)COc1ccc(Nc2ncc(Cl)c(Nc3ccccc3)n2)cc1,2.25 | |
| CCOC(=O)[C@H](Cc1ccc(cc1)[N+](=O)[O-])NC(=O)c2ccccc2,2.79 | |
| CCc1cccc(c1)N(C)C(=N)Nc2cccc3ccccc23,1.57 | |
| CC[S+]([O-])c1ncccc1C2(O)CCN(CC34CC(c5ccccc35)c6ccccc46)CC2,2 | |
| C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)CO)[C@@]4(C)CC(=O)[C@H]23,1.4 | |
| CN1C(=O)C=C(CCc2cccc(c2)c3ccccc3)N=C1N,3.8 | |
| CC1=CC2=NNC(=O)N2c3cc(ccc13)c4occc4,2.07 | |
| C[C@@H](NC1=CC(=O)CC1)c2ccc(Nc3ncc4cc(ccc4n3)c5ccncc5)cc2,3.2 | |
| CCCSc1ncccc1C(=O)NC2CCCCC2,3.24 | |
| C[C@@H](NC(=O)c1c(C)nn(c1NS(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(C)(C)C,1.2 | |
| COc1cc2ncnc(Nc3cc(NC(=O)c4ccnc(c4)N5CCOCC5)ccc3C)c2cc1OCCN6CCOCC6,3.19 | |
| COc1ccc2N=CC(=O)N(CCN3CC[C@H](NCc4cc5OCCOc5cn4)[C@H](O)C3)c2c1,.77 | |
| O[C@]1(CN2CCC1CC2)C#Cc3ccc(Oc4ccc(cc4)C(=O)NCc5ccnc6ccccc56)cc3,3.88 | |
| CCCNCC(O)COc1ccccc1C(=O)CCc2ccccc2,1.72 | |
| CCN(CC)c1ccc2C=C(C(=O)O)C(=O)Oc2c1,-.2 | |
| CC(C)N1CCN[C@H](C1)C(=O)N2CCN(CC2)C(=O)Nc3ccc(Cl)c(Cl)c3,2.21 | |
| CCOC(=O)\C=C\[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H](CC(=O)[C@@H](NC(=O)c2cc(C)on2)C(C)C)Cc3ccc(F)cc3,2.8 | |
| C[C@@H]1CN(C[C@H](C)O1)c2nc(N3CCOC[C@@H]3C)c4ccc(nc4n2)c5ccccc5,3.75 | |
| CN1N(C(=O)C=C1C)c2ccccc2,.11 | |
| CC1=CN([C@H]2CCCN(Cc3ccc(C(=O)O)c(Oc4cccc(F)c4)c3)C2)C(=O)NC1=O,-1.03 | |
| CC(C)[C@H](N)C(=O)OCCOCn1cnc2C(=O)N=C(N)Nc12,-1.3 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2CCCN(CCc3ccccc3)C2,1.65 | |
| CNc1c(Br)cnc2[nH]c(nc12)c3ccc(cc3)S(=O)(=O)C,2.88 | |
| Clc1ccc(CN2C[C@@H]3C[C@H]2CN3)cc1C(=O)NCC45CC6CC(CC(C6)C4)C5,1.45 | |
| Clc1ccc2N=C3NC(=O)CN3Cc2c1Cl,1.86 | |
| OC(=O)c1cccnc1N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,1.71 | |
| CC(=O)Nc1nc(N)n(n1)c2ccccc2,-.2 | |
| CC(C)NC[C@H](O)COc1cccc2ccccc12,.99 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)Cc3ccccc3C(=O)O)C(=O)C(F)(F)F,1.14 | |
| CCN(CC)c1ccc2C=C(C(=O)C)C(=O)Oc2c1,2 | |
| CCOC(=O)c1c(nc2cc(C)ccn12)c3ccccc3,3.8 | |
| CN(c1ccc(cc1)c2cc(ccc2OCC(=O)O)C(F)(F)F)S(=O)(=O)C,-.81 | |
| CN(c1ccccc1)c2ccnc(Nc3cc(cc(c3)N4CCOCC4)N5CCOCC5)n2,3.47 | |
| Nc1ncnc2c1ncn2[C@@H]3O[C@H](CSCCCNC(=O)NCc4ccccc4)[C@@H](O)[C@H]3O,.9 | |
| COc1cc2ncnc(Nc3cc4ccccc4cn3)c2cc1OC,3.9 | |
| Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]56[C@@H](Oc1c25)c7[nH]c8ccccc8c7C[C@@]36O,2.7 | |
| CNC(=O)c1cnn(c1NS(=O)(=O)c2ccc(C)cc2)c3ccccc3,-.54 | |
| COCCNC(=O)c1ccc(Nc2ncc3cc(ccc3n2)c4ccnc(C)c4)cc1,3.56 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3c[nH]c4ncccc34)c2C(=O)N5C[C@H](O)CO5,2.04 | |
| O=S(=O)(Nc1nc(nn1Cc2ccccc2)c3ccccc3)c4ccccc4,1.25 | |
| CNC(=O)Nc1nc2ccc(cn2n1)c3cncc(c3)S(=O)(=O)NC(C)(C)C,1.58 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4ccccn34)N5CCN(CCO)CC5,3.2 | |
| NC1(CCC1)c2ccc(cc2)N3C(=O)c4ccccc4N=C3c5ccccc5,1.6 | |
| CC(=O)c1ccc2OCC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,.37 | |
| CCN(CC)CCOC(=O)c1ccc(N)cc1,0 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)S(=O)(=O)CC4CCCO4)n2,2.82 | |
| CC1(O)CN(C1)S(=O)(=O)c2ccc3C(=CNC(=O)c3c2)C(=O)NC[C@@H](O)CN4CCC(CC4)Oc5ccc(Cl)c(Cl)c5,2.54 | |
| NC(Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(=O)O,.97 | |
| O=C1C(=O)c2ccccc2c3ccccc13,2.6 | |
| Clc1ccc(CN2CCNCC2)cc1C(=O)NCC34CC5CC(CC(C5)C3)C4,1.84 | |
| CC1(C)CCC(=C(CN2CCN(CC2)c3ccc(cc3)C(=O)NS(=O)(=O)c4ccc(N[C@H](CCN5CCOCC5)CSc6ccccc6)c(c4)S(=O)(=O)C(F)(F)F)C1)c7ccc(Cl)cc7,.64 | |
| Fc1ccc(cc1)n2cc(C3CCNCC3)c4cc(Cl)ccc24,2.4 | |
| CS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4ccoc34)n2)c1,3.52 | |
| CCN1C=C(C=C(C)C1=O)[C@@]2(N=C(N)c3c(F)cccc23)c4cccc(c4)c5cc(ccn5)C#CC,4.4 | |
| COC(=O)NC1=CN=C(N(CC(=O)NC(C(C)C)C(=O)C(F)(F)F)C1=O)c2ccc(F)cc2,1.82 | |
| CCCCNc1nc(N)c2NC(=O)N(Cc3ccc(OCCN(C)C)nc3)c2n1,1.9 | |
| CC(N)C(=O)Nc1c(C)cccc1C,-.15 | |
| NC1CCN(CC1)c2nccc(C(=O)NCC34CC5CC(CC(C5)C3)C4)c2Cl,1.19 | |
| COc1ccc(cc1)C(=O)N2CCC(CC2)C(=O)c3ccc(F)cc3,2.92 | |
| Cc1ccc(OC(=O)N2CCN3CCC2CC3)cc1,1.02 | |
| CC(=O)Nc1ccc2cnn(c3cc(NC4CC4)n5ncc(C#N)c5n3)c2c1,3.44 | |
| CCN(CC)C(=O)c1ccc(C2=CC3(CCNCC3)Oc4ccccc24)c(O)c1,.77 | |
| CN1CCOc2nc(ccc12)C#Cc3ccccc3,3.8 | |
| CCOC(=O)CN(c1ccccc1C)S(=O)(=O)c2ccc(Cl)cc2,4.03 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2CCCN(C2)C(=O)Cc3ccccc3,1.32 | |
| [O-][n+]1cc(ccc1Cl)C(=O)Nc2ccc(F)cc2,1.38 | |
| N#Cc1ccc(Nc2nccc(NC3CC3)n2)cc1,3.01 | |
| Nc1ccccc1NC(=O)c2ccc(cc2)c3ncc(CN4CCC4)cc3C#N,1.22 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccncc3C#N)cn2)C(=O)OCC(F)F,2.3 | |
| CN(C)CC(O)COc1ccc(Nc2nccc(n2)N(CC#N)c3cc(Cl)ccc3Cl)cc1,2.4 | |
| CN(c1ccnc(Nc2cc(cc(c2)N3CCOCC3)N4CCCC4)n1)c5cc(CO)ccc5C,3.8 | |
| Cn1nc(cc1NC(=O)Nc2ccc(Cl)cc2)C(C)(C)C,3.97 | |
| CC1Nc2cc(Cl)c(cc2C(=O)N1c3ccccc3C)S(=O)(=O)N,1.64 | |
| Cn1cnc(c2ccccc2)c1C#Cc3ccnc(N)n3,2.94 | |
| CNC(=O)c1cc(C(=O)c2ccc(Cl)cc2)c(Br)[nH]1,3.1 | |
| CN1CC(C1)n2nccc2c3cc(Cl)ccc3Oc4cc(F)c(cc4F)S(=O)(=O)Nc5ncns5,1 | |
| Oc1ccc(Nc2nc(cs2)c3ccc(cc3)C#N)cc1,4.1 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccc(NC(=O)C)cc3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,2.09 | |
| Cc1ccc(cc1)S(=O)(=O)c2ccccc2,2.74 | |
| CC(NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4ccc(F)cc4,2.4 | |
| COc1cc2ncc(C(=O)N)c(Nc3ccc(F)cc3F)c2cc1NCCN4CCCCC4,2.52 | |
| COc1ccc(Sc2c(C)n(CC(=O)O)c3ccc(C)cc23)cc1,1.01 | |
| CC(NC(=O)c1c(C)nn(c1NS(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(C)(C)C,1.21 | |
| Cc1ccc2c(c1)c(Sc3ccc(Cl)cc3)c(C)n2CC(=O)O,2.18 | |
| Clc1cccc(NC(=O)c2ccccn2)c1,3.4 | |
| CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@@H]3CC[C@@H](C)CC3)C1=O,1.73 | |
| Clc1ccc(cc1)c2oc(cc2)C(=O)N(Cc3ccccn3)c4ccc(cc4)N5CCNCC5,3 | |
| O=C1NC=Nc2scc(c3cccs3)c12,2.18 | |
| CC(C)N1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c6cncn6C)c3C1=O,4.02 | |
| OCCN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1,3.6 | |
| O=C(NC1(CC1)C#N)[C@@H]2CCCC[C@H]2C(=O)N3CCN(CC3)c4nc5ncccc5s4,1.4 | |
| Nc1ccccc1NC(=O)c2ccc(cc2)c3nccs3,2.3 | |
| CCN1CCOc2cc(COc3ccccc3)cnc12,3.7 | |
| Nc1ncc([nH]1)c2ccc(F)cc2,1.39 | |
| Clc1cc(Nc2ncnc3[nH]nc(OCCN4CCCC4)c23)ccc1OCc5ccccn5,2.87 | |
| COc1ccc(cn1)c2ccc3nc(N)sc3c2,3.2 | |
| COc1ccc(cc1)c2ccnc(N)n2,2.08 | |
| O=C(NC1(CC1)C#N)[C@@H]2CCCC[C@H]2C(=O)N3CCc4[nH]c5ccccc5c4C3,2.66 | |
| NC(=O)NC(=O)C(Nc1ccc2CCCc2c1)c3ccccc3,3.3 | |
| COc1cc2nnc(C(=O)N)c(Nc3cccc(Cl)c3F)c2cc1N4CCN(C)CC4,2.35 | |
| CS(=O)(=O)Cc1cc(nc(n1)c2cccc(CO)c2)N3CCOCC3,1 | |
| Cc1ccc2c(c1)c(c(C)n2CC(=O)O)c3ccnc4c(cccc34)C#N,.52 | |
| CCCSc1ccc2nc(NC(=O)OC)[nH]c2c1,3.24 | |
| CCOc1ccc2nc(N)sc2c1,2.4 | |
| N(c1ccccc1)c2ccnc3ccccc23,2.78 | |
| C[C@]12N[C@H](Cc3ccccc13)c4ccccc24,1.6 | |
| COc1cc(ccc1Cn2ccc3ccc(cc23)C(=O)NCC4CCCC4)C(=O)NS(=O)(=O)c5ccccc5,1.93 | |
| NC1=NN(CC1)c2cccc(c2)C(F)(F)F,2.55 | |
| O[C@@H](CNCCCOCCNCCc1cccc(Cl)c1)c2ccc(O)c3NC(=O)Sc23,-.03 | |
| CC(C)(C(=O)Nc1oc(nn1)C(=O)Nc2ccc(cc2)N3CCOCC3)c4ccc(Cl)cc4,2.96 | |
| Cc1ccc(cc1)C(=O)N2CCC(CC2)C(=O)c3ccc(Cl)cc3,3.79 | |
| c1ccc(nc1)c2nc3ccccc3[nH]2,2.5 | |
| CCN(CC)C(=O)c1ccc(cc1)C(=C2CCN(Cc3ccc(F)cc3)CC2)c4cccnc4,3.65 | |
| OC(=O)CO[C@H]1[C@@H](Cc2ccccc12)NC(=O)c3cc4sc(Cl)c(Cl)c4[nH]3,1.38 | |
| COc1cc(CCc2cc(Nc3ccnc(NCc4ccccn4)n3)n[nH]2)cc(OC)c1,3.5 | |
| [O-][N+](=O)c1cc(ccc1NCCSc2ccccc2)S(=O)(=O)NC(=O)c3ccc(cc3)N4CCNCC4,-.04 | |
| Nc1cc(nc2ccc(Nc3cc(nc(N)n3)c4ccc(cc4)C(F)(F)F)cc12)c5ccc(F)cc5,1.54 | |
| Fc1cnc(NC(=O)[C@H](CC2CCOCC2)c3ccc(cc3)S(=O)(=O)C4CC4)s1,3.19 | |
| NC(=N)SCc1ccc(Cl)c(Cl)c1,1.28 | |
| N#Cc1ccc(cc1)C(c2ccc(cc2)C#N)n3cncn3,1.7 | |
| Cc1ccc(COC(=O)N2CCC(CNc3ncccn3)CC2)cc1,3.6 | |
| COC[C@H](C)Oc1cc(O[C@@H](C)Cc2ccccc2)cc(c1)C(=O)Nc3ccc(cn3)C(=O)O,1.5 | |
| Oc1ncc(NCc2ccccc2)c(O)n1,.82 | |
| COc1cc(ccc1Nc2ccccc2C(=O)O)c3ccc(Nc4ccccc4C(=O)O)c(OC)c3,1.8 | |
| COc1cc(cc(OC)c1OC)C(=O)c2cc(Cl)ccc2N,3.38 | |
| Nc1ccccc1NC(=O)c2ccc(cc2)c3ncccc3C#N,1.58 | |
| CN(C)CC1CCn2c(C1)c(C3=C(C(=O)NC3=O)c4cn(C)c5ccccc45)c6ccccc26,2.88 | |
| COc1ccc2cc(CCC(=O)C)ccc2c1,3.06 | |
| C[C@@H]1CN(CCN1C(=O)[C@@H]2CCCC[C@H]2C(=O)NC3(CC3)C#N)c4ccc5c(C)noc5c4,2.67 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2CCN(Cc3ccccc3)C2,1.49 | |
| Oc1ccc(NC(=O)c2ccc(O)cc2)cc1,1.5 | |
| COC(=O)[C@H](Cc1ccc(cc1)[N+](=O)[O-])NC(=O)c2cccc3ccccc23,3.58 | |
| COc1cc(ccc1Nc2ncc3N(C)C(=O)CCN(C4CCCCC4)c3n2)C(=O)NC5CCN(C)CC5,2.87 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)C(=O)N)n2,2.39 | |
| Cc1ccc(OCC(=O)O)c(c1)n2nc3ccccc3n2,-.84 | |
| C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)c5ccc(C)nc5)C(=O)N1,3.6 | |
| CC1=C(Cc2ccccc2)C(=O)n3nc(NCc4ccc(Cl)cc4)nc3N1,3.7 | |
| Fc1ccc2OCC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,.9 | |
| N(c1ccccc1)c2ccccc2,3.2 | |
| CSCCC(NC(=O)c1ccccc1)c2nc3ccccc3n2Cc4ccc(cc4)C#N,4.24 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccncc3C#N)cn2)C(=O)OC(C)(C)C,3.33 | |
| Oc1cccc2ccccc12,2.5 | |
| CCN1CCN(CC1)C(=O)c2cc3cc(Cl)ccc3[nH]2,3.14 | |
| COc1cccc2c1c(NS(=O)(=O)c3ccc(Cl)s3)nn2Cc4cccc(CNC(=O)[C@@H]5COCCN5)c4,1.61 | |
| COc1ccc2c(c1)cc(C(=O)O)n2Cc3ccc(Cl)c(Cl)c3,1.66 | |
| NC(=O)c1cccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)c1,1.61 | |
| C[C@H](N)C(=O)N[C@@H](CCc1ccccc1)\C=C\S(=O)(=O)c2ccccc2,1.66 | |
| CN1CCNc2nc(CCOc3ccc(C[C@H](NC(=O)c4c(Cl)cccc4Cl)C(=O)O)cc3)ccc12,.07 | |
| C(Sc1nc2cccnc2[nH]1)c3ccccc3,3.22 | |
| OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c2ccccc2)(C(F)(F)F)C(F)(F)F,4.5 | |
| C[C@H](Nc1nc(Nc2ncc(C#N)s2)cc(n1)N3CCOCC3)c4ncc(F)cn4,2.26 | |
| CCN(CC)CCNC(=O)c1ccc(N)cc1,-.92 | |
| CC(C)Oc1cc(OCCc2ccsc2)cc(c1)C(=O)Nc3ccc(cn3)C(=O)O,1.74 | |
| O=C(Nc1ccc(Nc2ccc(NC(=O)c3ccccc3)c4C(=O)c5ccccc5C(=O)c24)c6C(=O)c7ccccc7C(=O)c16)c8ccccc8,2.63 | |
| COc1ccc(cc1OC)C(=O)Nc2cc(NC(=O)c3cccc(c3)N(C)C)ccc2Br,3.49 | |
| COc1ccccc1CN[C@H]2CCCN[C@H]2c3ccccc3,1.5 | |
| NC(=O)c1cccc(O[C@@H]2C[C@H]3CC[C@@H](C2)N3CC4CC4)c1,.07 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)OCc3cc(C)nc(C)c3)C(=O)C(F)(F)F,2.38 | |
| COCCCNS(=O)(=O)c1ccc(Nc2nccc(n2)c3cnc4ccccn34)cc1,3.41 | |
| CN[C@@H](C)[C@H](O)c1ccccc1,-1.15 | |
| FC(F)(F)c1cccc2c3CN(CCc3[nH]c12)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,3.75 | |
| OC(=O)[C@H](Cc1ccc(OCCNc2nc3ccccc3[nH]2)cc1)NC(=O)c4c(Cl)cccc4Cl,.6 | |
| COc1nc(N)nc2c1ncn2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O,-.58 | |
| C[C@@H]1NC(C)(C)CO[C@@]1(O)c2cccc(Cl)c2,1.69 | |
| CCN(C1CCN(CCC(N2CCN(CC2)c3ccccc3)c4ccccc4)CC1)C(=O)Cc5ccc(cc5)S(=O)(=O)C,2.67 | |
| CN1CCN(CC1)C(=O)[C@@H]2CCCC[C@H]2C(=O)NCC#N,-.1 | |
| Fc1ccc(cc1Cl)C2CNCC=CC2,1.33 | |
| Clc1cc(Cl)cc(c1)S(=O)(=O)NCC(N2CCCCCC2)c3ccccc3,3.36 | |
| CN1CCC(CC1)(c2cc(nc(n2)c3cccc4[nH]ccc34)N5CCOCC5)S(=O)(=O)C,1.9 | |
| C[C@@H](NC(=O)c1cccnc1Oc2ccccc2)c3ccccc3,3.14 | |
| CC1=CN([C@H]2CCCN(C2)S(=O)(=O)c3ccc(O)c(Oc4ccc(Cl)cc4)c3)C(=O)NC1=O,2.12 | |
| CCN(C1CCN(CC[C@H](C2CCN(CC2)S(=O)(=O)C)c3cc(C)cc(C)c3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,1.93 | |
| CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1CCCN(CCc2ccc(OC)cc2)C1)C(C)(C)C,1.45 | |
| COC(=O)COc1ccc(O)cc1,.92 | |
| C(=C\c1nn[nH]n1)/c2ccccc2,-.4 | |
| CN(C)CCC=C1c2ccccc2C=Cc3ccccc13,2.83 | |
| Oc1ccc(CCNCCCCCCNC(=O)Nc2ccccc2)c3sc(O)nc13,1.26 | |
| CC1SC2=C(C(=O)O)C(=O)c3cc(F)c(cc3N12)N4CCNCC4,-1.1 | |
| COc1ccccc1S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,.89 | |
| O[C@H]([C@H](Cc1ccccc1)NC(=O)c2cc3cc(Cl)ccc3[nH]2)C(=O)N4C[C@@H](O)[C@@H](O)C4,2.8 | |
| CCOc1ccc(cc1)N2C(=O)c3cccnc3N=C2[C@@H](C)N(CC4CCN(C)CC4)C(=O)Cc5ccc(F)c(c5)C(F)(F)F,1.4 | |
| CC1(C)Cc2c(c3ccccc3)c(c(CC(=O)O)n2C1)c4ccc(Cl)cc4,3.07 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Oc3cccc4ccccc34)c2C(=O)N5CC[C@@H](O)C5,2.87 | |
| Fc1ccccc1COc2cc(OCCCN3CCCC3)ccc2C(=O)Nc4ccccc4,3.85 | |
| CCC(=O)NCC[C@@H]1CCc2ccc3OCCc3c12,2.57 | |
| CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c3ccccn3,2.5 | |
| Oc1ccc(CC(=O)c2ccc(O)cc2O)cc1,2.54 | |
| Clc1cccc(Cl)c1c2nnc3cccc(Cl)n23,2.66 | |
| CNCCCN1c2ccccc2CCc3ccccc13,1.24 | |
| C[C@@H](N1CCC[C@@H](C1)N2C=C(C)C(=O)NC2=O)c3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3,-.3 | |
| O[C@@H](CNCCc1cccc(CNCCc2ccccn2)c1)c3ccc(O)c4NC(=O)Sc34,-.07 | |
| CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(c(F)c2)n3ccc(c3)C#N,1.6 | |
| CS(=O)(=O)C1(CC1)c2cc(nc(n2)c3ccccc3)N4CCOCC4,2.6 | |
| COc1ccc2N=CC(=O)N(CCN3CC[C@H](NCc4ccc5OCC(=O)Nc5n4)[C@H](O)C3)c2c1,.39 | |
| Clc1ccc(cc1)S(=O)(=O)Nc2nnc(s2)c3ccccc3,1.14 | |
| CN1SC(=O)c2cc(ccc12)S(=O)(=O)NC3CC3,1.3 | |
| COc1ccc(cc1OC)c2cc(NC(=O)Cc3ccc4ccccc4c3)[nH]n2,3.1 | |
| CN([C@@H]1CCN(Cc2ccc(nc2)C(F)(F)F)C[C@@H]1F)C(=O)Cc3ccc(cc3)n4cnnn4,1.8 | |
| COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4CCCO4,.9 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccncc3C#N)cn2)c4noc(C)n4,2.6 | |
| COc1cc(ccc1Cn2ccc3ccc(NC(=O)OC4CCCC4)cc23)C(=O)NS(=O)(=O)c5ccccc5,2.2 | |
| CCCc1c(O)c(ccc1OCc2ccc(cc2)C(=O)O)C(=O)C,2.1 | |
| Clc1ccc(c(Cl)c1)c2nnc3cccc(Cl)n23,2.88 | |
| CCn1c(C)ncc1c2ccnc(Nc3ccc(cc3)S(=O)(=O)NCCOC)n2,2.44 | |
| ONC(=O)c1ccc(NS(=O)(=O)c2ccccc2)cc1,.75 | |
| CN1CCCCC1CCN2c3ccccc3Sc4ccc(cc24)[S+](C)[O-],1.6 | |
| Nc1ccnc(n1)c2cccnc2,.44 | |
| Cc1nc(C)c(nc1C(=O)N)c2ccc(cc2)[C@@H]3CC[C@@H](CC(=O)N)CC3,2.7 | |
| Oc1c2C(=O)N(NC(=O)c2nc3cc(Cl)ccc13)C(C4CCCC4)c5ccccn5,1.9 | |
| Cc1cccc(NS(=O)(=O)c2ccc(cc2)c3ccc(cc3)C#N)n1,2.42 | |
| C[C@@H](Oc1cc(cnc1N)c2cnn(c2)C3CCNCC3)c4c(Cl)ccc(F)c4Cl,2.33 | |
| Cc1onc(C)c1CCC2CCN(CC2)S(=O)(=O)CC3(CCOCC3)N(O)C=O,.9 | |
| Cc1ccccc1C(=O)NCC23CC4CC(CC(C4)C2)C3,4.28 | |
| CN1CCN(CC1)C(=O)c2ccc(cc2)C(=C3CCN(Cc4cscn4)CC3)c5cccc6cccnc56,1.98 | |
| CC1(C)N=C(N)N=C(N)N1c2ccc(Oc3ccc(Cl)cc3)c(Cl)c2,.79 | |
| COc1ccc(cc1)n2cnc3cc(NS(=O)(=O)c4ccccc4)ccc23,3.7 | |
| OC(=O)c1ccccc1CN2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,2.48 | |
| CNc1nc(C)c(s1)c2nc(Nc3cccc(c3)N4CCCN(CC4)C(=O)C)ncc2C#N,3.2 | |
| Fc1cc(cc(F)c1CN2CCOCC2)c3cccc4ncc(nc34)c5cnn(c5)C6CCNCC6,1.86 | |
| CCC(N(CCCN)C(=O)c1ccc(C)cc1)C2=Nc3ccsc3C(=O)N2Cc4cccnc4,.01 | |
| OC(=O)c1cc2cc(OCc3ccccc3)ccc2[nH]1,.4 | |
| OC(=O)c1ccccc1C(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,1.73 | |
| Cc1ccc(cc1NC(=O)c2ccc(OCc3ccccn3)cc2)c4c[nH]c(C)n4,2.97 | |
| CCc1c(C)nc(SCC(=O)Nc2nc(cs2)c3ccc(OC)cc3)nc1O,3.78 | |
| CO[C@H]1CN(CCN2C(=O)C=Cc3ccc(cc23)C#N)CC[C@H]1NCc4cc5OCCOc5cn4,.63 | |
| Nc1cc(c(cn1)c2cc(nc(n2)N3CCOCC3)N4CCOCC4)C(F)(F)F,2.7 | |
| OC(=O)CCc1ccc(OCc2cc(Cl)ccc2c3ccccc3)cc1,3.22 | |
| COc1ccc2CC3C4C=CC(O)C5Oc1c2C45CCN3C,.8 | |
| CNC(=O)c1cc(sc1NC(=O)N)c2ccccc2,3.19 | |
| C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC2C(=O)N(C)c3ccccc3c4ccccc24,3.6 | |
| C[C@H](NC(=O)c1cccc2CCN(Cc3ccc(Cl)cc3)c12)c4ccc(cc4)C(=O)O,1.47 | |
| CC(=O)Nc1cccc(Nc2ncnc(n2)N3CCC(CC3)OCc4ccc(OC(F)(F)F)cc4)c1C,4.4 | |
| CC(O)(C(=O)Nc1ccc(cc1)S(=O)(=O)c2ccc(F)cc2)C(F)(F)F,3.12 | |
| C[C@@H]1CN(C[C@H](C)N1)c2c(F)c(N)c3C(=O)C(=CN(C4CC4)c3c2F)C(=O)O,-.15 | |
| Cc1sc2c(C(=N[C@@H](CC(=O)OC(C)(C)C)c3nnc(C)n23)c4ccc(Cl)cc4)c1C,3.82 | |
| CSc1ccc(OCc2ccccc2)c(c1)C(=O)Nc3ccc(cn3)C(=O)O,1.6 | |
| Oc1ccc(cc1)c2nc3ccccc3s2,4.1 | |
| COc1cc(Nc2nc(N[C@@H](C)c3ncc(F)cn3)nc(N4CCOCC4)c2Cl)n[nH]1,2.85 | |
| Clc1cccc(NNC(=O)c2cccnc2Cl)c1,1.87 | |
| Cc1ccc(NC(=O)CCC2CCCCC2)cc1NC(=O)c3ccc(O)cc3,4.13 | |
| CCc1c(C(=O)C(=O)N)c2c(OCC(=O)N)cccc2n1Cc3ccccc3,2.1 | |
| Nc1cccc2C(=O)C(=O)c3ccccc3c12,2.31 | |
| COc1ccc2cc(ccc2c1)C(C)C(=O)O,.23 | |
| CCOC(=O)Nc1cccc(c1)[C@H](N2CCN(Cc3cccnc3)CC2)c4ccc(cc4)C(=O)N5CCC5,3.02 | |
| C1NC(Cc2ccccc12)c3ccccc3,1.9 | |
| CCN(CC)S(=O)(=O)c1ccc(cc1)c2cc(ccc2OCC(=O)O)C(F)(F)F,.67 | |
| CN(C)CCOC(C)(c1ccccc1)c2ccccn2,-.2 | |
| NCCc1ccc(O)c2nc(O)sc12,.33 | |
| COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c3cccnc13,2.09 | |
| CN(C)CC(O)COc1ccc(Nc2nccc(n2)N(CC#C)c3cc(Cl)ccc3Cl)cc1,3.2 | |
| COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3,2.23 | |
| OCC(=O)N1CCC[C@@H]1COc2cccc3ncnc(Nc4ccc(OCc5ccccn5)c(Cl)c4)c23,3.71 | |
| CCN(CC)C(C)C(=O)c1ccccc1,1.18 | |
| CCCN(CCC)C(=O)c1cccc(c1)C(=O)N[C@@H](Cc2ccccc2)[C@H](O)CNCc3cccc(OC)c3,2.7 | |
| Oc1cc(nc2ccccc12)c3ccccc3,2.54 | |
| Cc1cc(O)ccc1N2C(=O)c3ccc(O)cc3C2=O,2 | |
| FC(F)(F)c1cc(COCC(N2CCNCC2)c3cccc(Cl)c3)cc(c1)C(F)(F)F,4.2 | |
| COc1cc2ncnc(Nc3cc(NC(=O)c4cccc(c4)N(C)C)ccc3Cl)c2cc1OC,4.26 | |
| C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)nc(OCC45CC6CC(CC(C6)C4)C5)nc23,3.58 | |
| CC(C)NC(=O)c1ccc(C)c(c1)N2C=Nc3ccc(cc3C2=O)N4CCN(C)CC4,1.56 | |
| C[C@H](Nc1nc(Nc2ncc(C)s2)c(F)c(n1)N3CCOCC3)c4ncc(F)cn4,3.27 | |
| OC(=O)c1ccc(cc1)c2nnn(Cc3ccccc3F)n2,.3 | |
| CC(C)NCC(O)COc1nccs1,-.97 | |
| CNC(=O)c1cccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)c1,1.93 | |
| CC(C)NCC(O)COc1ccccc1CC=C,.99 | |
| CC(=O)Nc1ccc2c(c1)c(cn2CCO)c3cc(NC4CC4)n5ncc(C#N)c5n3,2.71 | |
| OC(=O)c1ccccc1O,-1.36 | |
| Cn1cnc(c2ccccc2)c1c3cc4c(N)ncnc4s3,2.94 | |
| CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1,.44 | |
| CC(C)C[C@@H](N1CCC[C@@H](C1)N2C=C(C)C(=O)NC2=O)c3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3,.91 | |
| COc1ccc(Cl)c(Nc2ncnc3cc(OC)cc(OC4CCN(C)CC4)c23)c1,3.6 | |
| CCOC(=O)c1ccc(OCCC2CCN(CC2)c3ccc(C)nn3)nc1,3.76 | |
| Cc1ccc2nc(CCNCCCO)ccc2c1NC(=O)CC34CC5CC(CC(C5)C3)C4,1.18 | |
| OCC(CO)Nc1nc(SCc2cccc(F)c2F)nc3nc(NC4CC4)sc13,3.11 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccc(cc3)C#N)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,2.76 | |
| C[C@@H](COCCCS(=O)(=O)CCNCCc1ccc(O)c2nc(O)sc12)c3ccccc3,2.32 | |
| CN(C)CC(O)COc1ccc(Nc2ncc(C)c(Nc3ccccc3)n2)cc1,2 | |
| CCCSc1nc(ccc1C(=O)NC2CCCCC2)N3CCCC(C3)C(=O)O,1.72 | |
| C[C@@H]1CCCN1CCc2oc3ccc(cc3c2)c4ccc(cc4)C#N,3.51 | |
| COc1cc2ncc(C(=O)N)c(Nc3cccc(Cl)c3)c2cc1OC,3.5 | |
| Brc1ccc(cc1)S(=O)(=O)NCC(N2CCCCCC2)c3ccccc3,3.21 | |
| Oc1ccccc1CCC(=O)Nc2ccccc2,2.71 | |
| C[C@@H]1CN[C@@H]2[C@@H](C1)O[C@]3(CC[C@H]4[C@@H]5CC=C6C[C@@H](O)CC[C@]6(C)[C@H]5CC4=C3C)[C@@H]2C,2.63 | |
| NC(=O)N1c2ccccc2C[C@H](O)c3ccccc13,.79 | |
| Nc1nnc(s1)c2ccccc2,1.8 | |
| Fc1ccc(C2CCN(CC2)C(=S)COCc3ccncc3)c(Cl)c1,4.23 | |
| COc1ncnc(NS(=O)(=O)c2ccc(N)cc2)c1OC,-.73 | |
| C[C@H]1CCCN1CCc2oc3ccc(cc3c2)c4ccc(cc4)C#N,3.25 | |
| COc1cc(Nc2nc(N[C@@H](C)c3ncc(F)cn3)ncc2Cl)n[nH]1,2.53 | |
| CC(N1NC(=O)C2=C(C1=O)C(=O)c3ccc(Cl)cc3N2)c4ccsc4,.9 | |
| CCN1CCN(CC1)C(=O)c2cc3cc(F)ccc3[nH]2,2.28 | |
| CC(C)C[C@H](CO)Nc1nc(SCc2ccccc2)nc3nc(N)sc13,4.2 | |
| CN1CCC[C@@H]1CCO[C@](C)(c2ccccc2)c3ccc(Cl)cc3,3.48 | |
| O=C(N[C@H]1CN2CCC1CC2)c3ccc(s3)c4ccccc4,1.9 | |
| CC(NCC(O)c1ccc(cc1)[N+](=O)[O-])C23CC4CC(CC(C4)C2)C3,3.53 | |
| CC1=CN(C2CCCN(Cc3cccc(Oc4ccc(C)cc4)c3)C2)C(=O)NC1=O,3.38 | |
| CCCN(CCNCCc1ccc(O)c2NC(=O)Sc12)C(=O)CCOCCc3ccccc3,2.23 | |
| O=C1N=C(NCc2ccccc2)SN1Cc3ccccc3,3.01 | |
| COc1cc(OC)c(cc1NC(=O)Cc2ccnc(F)c2)S(=O)(=O)N3c4ccccc4Oc5ccccc35,3.37 | |
| OC(=O)c1ccc2c(c1)nc(Nc3cccc(Cl)c3)c4ccncc24,1.29 | |
| NC(=N)Nc1nc(CSCCC(=N)NS(=O)(=O)N)cs1,-.6 | |
| CN(CCO)C(=O)c1ccc(cc1)[C@@H](N2CCN(Cc3ccc(F)cc3)CC2)c4cccc(NC(=O)C5CC5)c4,3.38 | |
| CCN(C1CCN(CC[C@H](C2CCN(CC2)S(=O)(=O)C)c3cccc(c3)C(F)(F)F)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,1.9 | |
| CN1CCCC(COc2nccc(Nc3cc(NC(=O)c4ccnc(c4)N5CCOCC5)ccc3C)n2)C1,1.9 | |
| O[C@H](CNC(=O)C1=CNC(=O)c2c(F)cccc12)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,3.15 | |
| CN(C)CCCN(C)S(=O)(=O)c1ccc(Nc2nccc(n2)c3cnc4ccccn34)cc1,2.16 | |
| OC1=CC(=O)C2=C(O1)c3ccccc3N(Cc4ccccc4)C2=O,1.97 | |
| CC(O)(C(=O)Nc1ccc(cc1)S(=O)(=O)c2ccc(O)cc2)C(F)(F)F,2.78 | |
| CCCSc1ncccc1C(=O)N(C)[C@H]2[C@@H]3CC4C[C@H]2C[C@@](O)(C4)C3,2.48 | |
| Cn1cncc1c2c3C(=O)N(CC#CCO)C(=O)N(CC4CC4)c3nn2Cc5ccnc6ccc(Cl)cc56,2.55 | |
| Fc1cccc(F)c1CS(=O)(=O)N2CCN(CC2)c3ncccc3C(F)(F)F,3.9 | |
| CS(=O)(=O)c1ccc(cc1)c2cc(C(=O)N[C@H]3CCCNC3)c(NC(=O)N)s2,.68 | |
| Cc1onc(C(=O)N)c1C(=O)Nc2nccs2,1.63 | |
| CNCCC(Oc1ccc(cc1)C(F)(F)F)c2ccccc2,1.92 | |
| CCn1cnc(c2ccccc2)c1c3nc4c(N)ncnc4s3,2.97 | |
| CCCc1c(O)c(ccc1OCCCCSCC(=O)O)C(=O)C,1.3 | |
| CN(c1ncccc1CNc2nc(Nc3ccc4NC(=O)Cc4c3)ncc2C(F)(F)F)S(=O)(=O)C,2.63 | |
| CCc1nc2cc(O)ccc2c(Oc3ccc(\C=C\C(=O)O)cc3)c1c4ccccc4,3 | |
| Cc1ccc(s1)C(NC(=O)c2ccccc2O)C(=O)Nc3c(C)cccc3C,4.05 | |
| COCCOc1nc(N)c2NC(=O)N(Cc3cccc(CC(=O)OC)c3)c2n1,1.86 | |
| C[S+]([O-])c1ccc(cc1)c2nc(c3ccc(F)cc3)c([nH]2)c4ccncc4,3.34 | |
| CCC(CC)n1nc(C)c(C(=O)N[C@@H](C)C(C)(C)C)c1NS(=O)(=O)c2ccc(C)cc2,1.88 | |
| CN1CCN(CC(=O)Nc2ccc(C3=CC=CN4C(=O)C=C(N=C34)N5CCOCC5)c6sc7ccccc7c26)CC1,2.6 | |
| NC1=NC2(CCN(CC2)C(=O)c3ccc(nc3)C#N)Nc4c(F)ccc(F)c14,.79 | |
| CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(N3Cc4cccnc4C3)c(F)c2,2.88 | |
| CC[C@H](NC(=O)c1c([S+](C)[O-])c(nc2ccccc12)c3ccccc3)c4cccnc4,2.2 | |
| OCC(=O)N1CCC(CC1)c2[nH]nc(c3ccc(Cl)cc3F)c2c4ccncn4,1.79 | |
| CC(C)Oc1cc(n[nH]1)n2cnc3ccc(N[C@@H](CO)c4ccc(F)cn4)nc23,2.79 | |
| NC(=O)c1cnc2[nH]c(nc2c1NCCCNC(=O)C3CCC3)c4ccc(OCCN5CCCCC5)cc4,2.48 | |
| CNC(=O)OC[C@@H](C)N(c1cc(Cl)ccc1CO)S(=O)(=O)c2ccc(Cl)cc2,3 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(C(=O)NCCN(C)C)c(F)c3)n2,1.96 | |
| CC1(CCC(=O)N1Cc2cccs2)C(=O)NC3CCCCC3,2.15 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4ccccn34)N5CCN(CC5)C(=O)N,3.3 | |
| NC(=O)c1cccc(c1)[S+]([O-])[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4,1.1 | |
| CN(C)c1nc(Cc2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2)nc(N(C)C)c1CC(=O)O,1.46 | |
| CCC(CC)NC(=O)c1nnn(c1NS(=O)(=O)c2ccc(C)cc2)c3ccccc3,.46 | |
| Nc1nc(SCc2ccccc2)nc3c1ncn3[C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O,1.24 | |
| CN1C(=O)N(C)c2[nH]c(nc2C1=O)c3cccnc3,.7 | |
| CO[C@@H]1CN(Cc2ccc(cc2)C(F)(F)F)CC[C@@H]1N(C)C(=O)Cc3ccc(cc3)n4cnnn4,3.1 | |
| COc1ccc2cc(ccc2c1)[C@H](C)C(=O)O,.13 | |
| CN(C)C1=C(C)N(C)N(C1=O)c2ccccc2,.78 | |
| CCC(CC)CNC(=O)c1ccc2c(c1)c(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c4ccccc4C)cn2C,2.7 | |
| NC(=O)c1cncc(c1)c2ccc(cc2)[C@@H]3CC[C@@H](CC(=O)O)CC3,.22 | |
| CC(C(=O)O)c1ccc(c(F)c1)c2ccccc2,.85 | |
| COc1cc(ccc1Nc2ncc(c(n2)c3cnc4ccccn34)C(F)(F)F)N5CCN(CC5)C(=O)C,3.7 | |
| NC1(CCC1)c2ccc(cc2)c3ncc4nccn4c3c5ccccc5,1.3 | |
| COC[C@H](C)Oc1cc(Oc2cc(F)cc(F)c2)cc(c1)C(=O)Nc3ccc(cn3)C(=O)O,1.36 | |
| CCC(C)(C)C[C@@H](N1CCC[C@@H](C1)N2C=C(C)C(=O)NC2=O)c3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3,1.37 | |
| Fc1cccc(c1)C(COCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)N3CCNCC3,3.2 | |
| COc1cc(F)ccc1c2cncc(CNC(=O)c3ccccn3)c2,3.2 | |
| CSCc1cc(nc(n1)c2ccccc2)N3CCOCC3,3.26 | |
| CN(C)CCCNc1cc(nc2c(cnn12)C#N)n3ccc4ccc(NC(=O)C)cc34,1.62 | |
| CC(=O)Nc1ccc2ccn(c3cc(NCCN4CCCC4)n5ncc(C#N)c5n3)c2c1,2.24 | |
| Clc1cccc2c3CN(CCc3[nH]c12)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,3.59 | |
| Oc1ccc(cc1)C2=COc3cc(O)ccc3C2=O,2.46 | |
| Nc1ccc2[nH]c(Cc3ccc(Oc4ccccc4)cc3)nc2c1,3.8 | |
| CN1C(=O)C(=Cc2cnc(NC(CCO)CCO)nc12)Oc3ccc(F)cc3F,1.5 | |
| CCc1ccc(NC(=O)c2ccc3cc(ccc3c2)C(=N)N)cc1,1.1 | |
| CC#Cc1ccnc(c1)c2cc(ccc2O)C3(N=C(C)C(=N3)N)C4CC4,3.6 | |
| Fc1ccc(cc1)C(NC(=O)CC2CCN(Cc3ccn(c3)c4ccc(cc4)C(F)(F)F)CC2)C5=CNC(=O)C(=C5)Cl,3.12 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC=O)C(=O)C(F)(F)F,1.84 | |
| COc1cc(ccc1Nc2ncc(C)c(n2)c3cnc4ccccn34)N5CCN(CC5)C(=O)C,2.9 | |
| Nc1cccc2C(=O)N(Cc3cccc(Cl)c3)C(=O)c12,3.18 | |
| NC(=O)Nc1cc(sc1C(=O)N[C@H]2CCCNC2)c3ccccc3,1.04 | |
| Nc1nc(Cl)nc(NCc2ccccc2)n1,2.26 | |
| COc1cccc(COCC(O)CN2CCC(CC2)C(=O)N)c1,-.5 | |
| Oc1ccc(CCNCCCCCCOCCc2ccccc2)c3sc(O)nc13,2.21 | |
| COC[C@H](C)Oc1cc(Oc2ccccc2)cc(c1)C(=O)Nc3ccc(cn3)C(=O)O,.95 | |
| Clc1ccc2ncc(c3cccc(NC4CNC4)n3)n2c1,1.19 | |
| NC(=N)Nc1ccc(cc1)C(=O)Oc2ccccc2,-.21 | |
| NC1(CCC1)c2ccc(cc2)C3=NN4C=CC(=O)N=C4C=C3c5ccccc5,.2 | |
| CCOc1ccc(NC(=O)C)cc1,1.5 | |
| O=C(CC12CC3CC(CC(C3)C1)C2)Nc4ccc5[nH]ncc5c4,4.03 | |
| OC(=O)Cc1csc(n1)c2ccc(Cl)cc2,-.22 | |
| Cc1oc(cc1)c2ccc(cc2F)S(=O)(=O)N3CCC[C@H]3C(=O)N4CC[C@@H](N)C4,1.2 | |
| Cc1onc(c1)[C@H](O)[C@](C)(OCc2ccc(cc2)c3ccccc3)C(=O)NO,2.88 | |
| COc1cccc(Oc2cncnc2O)c1,.59 | |
| CC(C)Oc1cc(Nc2nc3c(cc2F)ncn3[C@@H](CO)c4ccc(F)cn4)n[nH]1,2.97 | |
| OC(=O)c1cccc(c1)c2ccc3c(C(=O)NCC45CC6CC(CC(C6)C4)C5)c(Cl)ccc3n2,2.84 | |
| Nc1nc(N)c(nc1Cl)C(=O)Nc2ccccn2,2.67 | |
| CN1CCN(CC1)C(=O)c2cc3cc(Cl)ccc3[nH]2,2.4 | |
| CCn1c(C)c(C(=O)O)c(c2cccc(c2)N3CCN(CC3)c4ccc(NS(=O)(=O)c5ccc(N[C@H](CCN6CCC(O)CC6)CSc7ccccc7)c(c5)S(=O)(=O)C(F)(F)F)cc4)c1c8ccc(Cl)cc8,4.2 | |
| CC1CN(C1)C(=O)c2nnc3c(cccc3c2N)c4ncccn4,1.21 | |
| OC[C@H](Nc1ncc(Cl)c(Nc2cc([nH]n2)C3CC3)n1)c4ccc(F)cc4,3.75 | |
| C[C@H]1COCCN1c2cc(CS(=O)(=O)C)nc(n2)c3ccc4[nH]ccc4c3,2.38 | |
| COCCCc1cc(Nc2nc(NCc3onc(C)c3)ncc2Br)n[nH]1,3.07 | |
| OCc1ccc(OC2CCN(CC3CCN(CC3)[C@@H](Cc4ccccc4)C(=O)O)CC2)cc1Cl,.8 | |
| OC(=O)CNCCNc1ccc(Cl)c(c1)C(=O)NCC23CC4CC(CC(C4)C2)C3,1.94 | |
| COc1cc(ccc1C2CC2)N3CCN([C@H](C)C3)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,3.49 | |
| CCNC(=O)c1ccc(C)c(c1)N2C=Nc3ccc(cc3C2=O)N4CCN(C)CC4,1.47 | |
| O=C(Nc1nc(cs1)c2ccccc2)c3cccnc3,3.62 | |
| CS(=O)(=O)n1c2ccccc2c3cc(NC(=O)CCc4ccncc4)ccc13,3.4 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccncc3C#N)cn2)C(=O)OCC(F)(F)F,3 | |
| Nc1nnc(Cc2ccc(Cl)cc2)s1,2.34 | |
| OC(=O)c1c(C#N)c2ccccc2n1Cc3ccc(Cl)c(Cl)c3,1.26 | |
| O[C@@H](CNCCc1cccc(c1)c2cccc(CNCc3ccccc3)c2)c4ccc(O)c5NC(=O)Sc45,2.32 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)S(=O)(=O)CCCN4CCOCC4)n2,2.43 | |
| C[C@H](CO)Nc1nc(SCc2ccccc2F)nc3nc(N)sc13,3.12 | |
| OCC[C@]1(CCCNC1)c2ccc(Cl)c(Cl)c2,.62 | |
| C=CCN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)Nc4ccccc4,3.6 | |
| C[C@H](NC(=O)c1c(C)nn(c1NS(=O)(=O)c2ccc(cc2)C#N)c3ccc(F)cc3)C(C)(C)C,.45 | |
| OC(=O)[C@H](Cc1ccc(F)cc1)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,2.98 | |
| CS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4ncoc34)n2)c1,2.5 | |
| COCCC(=O)N(C)c1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,3.23 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccc(cc3)C#N)cn2)C(=O)OC(C)(C)C,2.89 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)N4CCN(CC4)S(=O)(=O)CCN(C)C)n2,2.52 | |
| Nc1ccc2ccccc2n1,1.7 | |
| CCCCN1Cc2c(O)n3nc(cc3nc2C1=O)c4occc4,.8 | |
| CN1C=C(C(=O)NC[C@@H](O)CN2CCC(CC2)Oc3ccc(Cl)c(Cl)c3)C(=CC1=O)C(F)(F)F,2.76 | |
| Nc1nc2ccc(cc2s1)c3cccc(O)c3,3.1 | |
| CC#CCN1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c3C1=O)c6cncn6C,3.61 | |
| C[C@@H]1CN(CCN1C(=O)[C@@H]2CCCC[C@H]2C(=O)NC3(CC3)C#N)c4ccc5c(C)nn(C)c5c4,2.7 | |
| Cc1nccc(c1Cl)c2ccc(cc2)c3nc4ccncc4c(O)c3C#N,2 | |
| O=C1C=C(Oc2c1cccc2c3ccccc3)N4CCOCC4,2.9 | |
| COc1ncc2C=CC(=O)N(CCN3CCC(CC3)NCc4cc5OCCOc5cn4)c2n1,.2 | |
| COc1cc(ccc1Cc2cn(C)c3ccc(NC(=O)CC4CCCC4)cc23)C(=O)O,2 | |
| Cc1c(c2cc(F)ccc2n1CC(=O)O)S(=O)(=O)c3ccc(Cl)cc3,-.16 | |
| NS(=O)(=O)c1ccc(Nc2nccc(Nc3c(Cl)ccc4OCOc34)n2)cc1,2.7 | |
| CCC(C)(CC)C[C@@H](N1CCC[C@@H](C1)N2C=C(C)C(=O)NC2=O)c3ccc(C(=O)O)c(Oc4cccc(Br)c4)c3,1.97 | |
| CC1(C)[C@@H]2CC[C@@]1(CS(=O)(=O)N3CCN(CC3)c4ccc(cn4)C#N)C(=O)C2,2.46 | |
| NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C(Cl)Cl)cc1Cl,.37 | |
| Cc1nc2ncnn2c(O)c1CCOC(=O)c3ccccc3F,.99 | |
| O[C@H](CNS(=O)(=O)c1cccc(c1)C#N)CN2CCC(CC2)Oc3ccc(Cl)c(Cl)c3,3.42 | |
| O=C(NCCCCc1ccccc1)c2ccccc2,3.8 | |
| CC(C)C[C@H](NC(=O)N1CCOCC1)C(=O)NCC#N,.08 | |
| NC(=O)C1CCCCC1,.9 | |
| CN(C)c1ncnc2nc[nH]c12,.95 | |
| Nc1nonc1\C(=N\O)\Nc2ccc(F)c(Cl)c2,2.7 | |
| COc1ccc(cc1)S(=O)(=O)Nc2ccccn2,.87 | |
| Cc1ccc(cc1)c2csc3ncnc(O)c23,2.59 | |
| CCOc1ccccc1c2ccc(cc2)c3nc4ccncc4c(O)c3C#N,3 | |
| COc1ccc(NC(=O)C=C)cc1,1.68 | |
| CC1=CN([C@H]2CCCN(C2)S(=O)(=O)c3ccc(O)c(Oc4cccc(Br)c4)c3)C(=O)NC1=O,2.3 | |
| CS(=O)(=O)c1ccc2C(=CNC(=O)c2c1)C(=O)NC[C@@H](O)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,2.63 | |
| CN1CCC[C@H]1c2ccccn2,.44 | |
| Oc1ccc(cc1)c2oc3ccc(O)cc3n2,3.4 | |
| CC[C@H](Nc1ncnc2[nH]cnc12)C3=Nc4cccc(F)c4C(=O)N3c5ccccc5,2.72 | |
| Cn1c(Nc2ccc(cc2)C(F)(F)F)nc3cc(Oc4ccnc(c4)c5ncc([nH]5)C(F)(F)F)ccc13,3.45 | |
| Nc1nc(ns1)c2ccccc2,2.2 | |
| N\C(=C(/C#N)\c1ccccc1C(F)(F)F)\Sc2ccc(N)cc2,3.4 | |
| CC(N(O)C(=O)N)c1cc2ccccc2s1,2.05 | |
| Cc1onc(NC(=O)CSc2nc(C)cc(C)n2)c1,1.52 | |
| COc1c(cc2ccccc2c1C(=O)N(C)C[C@@H](CCN3CCC(CC3)N4CCCNC4=O)c5ccc(Cl)c(Cl)c5)C#N,3 | |
| CNC1=Nc2ncccc2C(=NC1c3ccns3)c4occc4,1.44 | |
| CN1C(=O)N(C)c2ncn(CC(O)CO)c2C1=O,-1.25 | |
| CN1C(=O)CC(C)(CCc2cccc(c2)c3ccccc3)N=C1N,2.03 | |
| COc1cc(ccc1Cc2cn(C)c3ccc(cc23)C(=O)NCCc4ccccc4)C(=O)NS(=O)(=O)c5ccccc5C,2.51 | |
| Cc1ccc(cc1)c2nn(c3ncnc(N)c23)C(C)(C)C,4.1 | |
| COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC4CCN(CC(=O)N)CC4,3.1 | |
| NC(=O)c1ccc(Br)cc1,1.75 | |
| C1CCN(CC1)c2ncnc3[nH]cnc23,1.84 | |
| CCOc1cccc(Nc2oc(nn2)C(=O)Nc3ccc(nc3)N4CCOCC4)c1,3.6 | |
| C[C@H](Oc1ccc(SCCCCCc2ccccc2)cc1)C(=O)c3nc(C)c(CCCC(=O)O)s3,2.03 | |
| Fc1ccc(CN2CCN(CC2)[C@H](c3ccc(cc3)C(=O)N4CCC4)c5cccc(NC(=O)C6CC6)c5)cc1,3.58 | |
| N[C@H](Cc1c[nH]c2ccccc12)C(=O)O,-.92 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c(SCCCO)c(Cc3ccccc3C(F)(F)F)sc12,4.05 | |
| CN1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c6oc(cc6Cl)S(=O)(=O)C)c3C1=O,3.97 | |
| C[C@H](NC(=O)c1c(C)nn(C2CCC2)c1NS(=O)(=O)c3ccc(C)cc3)C(C)(C)C,1.57 | |
| Clc1ccc2C(=O)C3=C(Nc2c1)C(=O)NN(Cc4cccs4)C3=O,1.52 | |
| COc1ccc2N=CC(=O)N(CCN3CC[C@@H](NCc4ccc5OCC(=O)Nc5n4)[C@@H](F)C3)c2c1,.83 | |
| O=C(Nc1ccc(nc1)n2ccnc2)c3ccc(cc3)C#N,2.2 | |
| Nc1[nH]ncc1S(=O)(=O)c2ccccc2,1.1 | |
| Cc1ccc(cc1)S(=O)(=O)Nc2c(C(=O)NCC(C)(C)C)c(C)nn2c3ccccc3,1.46 | |
| CS(=O)(=O)Cc1cc(nc(n1)c2cccc3[nH]ccc23)N4CCOCC4,1.7 | |
| C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)nc(OCC4CCC(F)(F)CC4)nc23,1.72 | |
| CCn1c2ccccc2c3cc(NC(=O)CCc4ccncc4)ccc13,3.75 | |
| CCS(=O)(=O)c1ccc(c2cc(Cl)ccc2OCC(=O)O)c(c1)C(F)(F)F,.62 | |
| COc1ccccc1C[C@H](N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2)C(=O)O,2.77 | |
| COc1cc2nnc(C(=O)N)c(Nc3ccc(F)cc3F)c2cc1N4CCN(C)CC4,2.36 | |
| Fc1ccc2cn[nH]c2c1,2.3 | |
| CC(C)N(CCCNC(=O)Nc1ccc(cc1)C(C)(C)C)C[C@H]2O[C@H]([C@H](O)[C@@H]2O)n3ccc4c(N)ncnc34,2.4 | |
| CCC1(CCC(=O)NC1=O)c2ccc(N)cc2,.6 | |
| OC(=O)CCCc1ccc(cc1)N(CCCl)CCCl,1.47 | |
| NC1=NC2(CCN(CC2)C(=O)c3ccc(cc3)C#N)Nc4cccc(F)c14,.66 | |
| Cc1ccc(cc1c2ccc(nc2)C(=O)NCC3CC3)C(=O)NC4CC4,3.36 | |
| CC(C)N=C1C=C2N(c3ccc(Cl)cc3)c4ccccc4N=C2C=C1Nc5ccc(Cl)cc5,3.17 | |
| CO[C@@H]1CN(CCN2C(=O)C=Nc3ccc(OC)cc23)CC[C@H]1NCc4ccc5OCC(=O)Nc5n4,.97 | |
| Oc1cc(OCc2ccccc2)ccn1,1.69 | |
| CN(C)CC(O)COc1ccc(Nc2cc(Nc3cc(Cl)ccc3Cl)ncn2)cc1,2.6 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3ccccc3C(F)(F)F)c2C(=O)N4C[C@H](O)CO4,3.15 | |
| CN1CCN(CC1)c2ccc(Nc3ncc(C)c(Nc4cccc(c4)S(=O)(=O)NC(C)(C)C)n3)cc2,2.84 | |
| COc1cc2ncnc(Nc3ccncc3)c2cc1OC,2.22 | |
| N(c1ccccc1)c2[nH]nnc2c3ccccc3,3.37 | |
| O=C(NC1(CC1)C#N)[C@@H]2CCCC[C@H]2C(=O)N3CCN(CC3)c4nc5cnccc5s4,1.66 | |
| O[C@@H](CNCCc1ccc(CNCCc2ccccc2)cc1)c3ccc(O)c4NC(=O)Sc34,1.11 | |
| NS(=O)(=O)c1cc(Cl)c(Cl)c(c1)S(=O)(=O)N,.92 | |
| Fc1ccc(cc1)c2cn3ccccc3n2,3.1 | |
| Fc1ccc(CC2=NNC(=O)c3ccccc23)cc1N4C(=O)CCC4=O,1 | |
| O=C(Nc1cc(nn1c2ccccc2)c3ccccc3)c4cccc(c4)C#N,3.82 | |
| CN(C)c1cccc2c(cccc12)S(=O)(=O)N(C)CC(=O)O,-1.45 | |
| Cc1cc(on1)c2ccc(cc2F)N3C[C@H](Cn4ccnn4)OC3=O,1.99 | |
| COc1ccnc(NC2CCN(CC2)C(=O)c3ccccc3)c1,2.06 | |
| CCC(=O)N[C@H]1CC[C@H](C1)C(=O)N(C)c2ccc(cc2)c3oc4ccccc4n3,3.4 | |
| Nc1c(cnn1c2ccc(F)cc2)C(=O)c3cccc(OC[C@H](O)CO)c3,1.94 | |
| O=C1C=C(N=C2N(Cc3cccc4ccccc34)C=CN12)N5CCOCC5,3.3 | |
| COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCN4CCN(C)CC4,3.3 | |
| O=C1NCCc2[nH]c(cc12)c3ccncc3,1.49 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,3 | |
| COc1cc(ccc1OCCN2CCCC2)N3C=Nc4cc(sc4C3=O)c5ccc(Cl)cc5,2.74 | |
| CN(C)c1ccnc2sc3C(=O)N(C=Nc3c12)c4ccccc4,2.34 | |
| CN1CCc2c(NC(=O)Cc3ccccc3)c4ccccc4nc12,2.8 | |
| C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)nc(OC(C4CC4)C(F)(F)F)nc23,1.83 | |
| Cc1c[nH]c(\C=C\2/C(=O)Nc3ccccc23)c1CCC(=O)O,1.2 | |
| COc1ccc(Nc2nccc(n2)c3cnc(C)n3C(C)C)cc1,3.43 | |
| C[C@H](Oc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c3ncc(F)cn3,1.82 | |
| Clc1cnc(cc1C(=O)NCC23CC4CC(CC(C4)C2)C3)N5CCNCC5,2.09 | |
| Cc1c(Sc2ccc(Cl)cc2)c3cc(Cl)ccc3n1Cc4nnn[nH]4,3.25 | |
| CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C2=O)C(=O)O,-.86 | |
| CN(C)CCOC(c1ccccc1)c2ccccc2C,1.47 | |
| CC(C)c1noc(n1)N2CCN([C@H](C)C2)c3ncc(OCc4ccncc4C#N)cn3,3.1 | |
| C[C@@H](N(CC1CCS(=O)(=O)CC1)C(=O)Cc2ccc(c(F)c2)C(F)(F)F)C3=Nc4ncccc4C(=O)N3c5ccc(Cl)cc5,2.9 | |
| CCOc1ccc2nc(NC(=O)CC)sc2c1,3.4 | |
| CC1=CN([C@H]2CCCN(C2)S(=O)(=O)c3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3)C(=O)NC1=O,-1.28 | |
| [O-][N+](=O)c1ccc(cc1)C2=Nc3ccccc3C(=O)N2,2.5 | |
| O=C(NCc1ccccn1)c2ccc(Oc3ccccc3)cc2,2.7 | |
| CN1CCN(CC1)S(=O)(=O)c2ccc(cc2F)c3cnc(N)c(n3)C(=O)Nc4cccnc4,2.66 | |
| COc1ccccc1C2=COc3cc(O)ccc3C2=O,2.55 | |
| Cn1cc(CN2CCc3cc4nc(N)sc4cc3CC2)cn1,1.06 | |
| Fc1ccc(cc1F)N2C=CN=C(SCC(=O)NC3CCCC3)C2=O,2 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)OCc3ccccn3)C(=O)C(F)(F)F,1.91 | |
| Cn1c(SCc2c(Cl)cccc2Cl)nnc1c3ccc4nonc4c3,3.35 | |
| COc1ccc(cc1)C(=O)CS(=O)(=O)c2ccccc2,1.96 | |
| CN(C)CC\C=C\1/c2ccccc2Sc3ccc(Cl)cc13,3.42 | |
| Clc1ccc(cc1)C2(CCC2)C(=O)Nc3oc(nn3)C(=O)Nc4ccc(cc4)N5CCOCC5,3.2 | |
| C[C@H](CO)Nc1nc(SCc2ccccc2)nc3NC(=O)Nc13,2.75 | |
| COCCN(C)Cc1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,2.65 | |
| CC(COc1ccccc1)NC(C)C(O)c2ccc(O)cc2,.56 | |
| CN(C1CCN(Cc2ccc(cc2)C(F)(F)F)CC1)C(=O)Cc3ccc(NC(=O)C)cc3,2.9 | |
| C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCN(CCc2ccc(Cl)cc2Cl)CC1)N(O)C=O)c3ncc(F)cn3,3.27 | |
| CN1CCN(CC1)c2ccc(Nc3ncc(F)c(N[C@@H]4[C@@H]5C[C@@H](C=C5)[C@@H]4C(=O)N)n3)cc2C,2.9 | |
| Cc1ccc2c(c1)c(Sc3ccccc3)c(CC(=O)O)n2C,1.74 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(cc3)N4CC(C4)NC(=O)C)ncc2F,2.76 | |
| NC(=O)c1cc2ccccc2nc1N,1.07 | |
| O=C(N1CCNCC1)c2cc3ccccc3[nH]2,.6 | |
| N#CCc1c[nH]c2ccc(OCc3ccccc3)cc12,3.71 | |
| CN([C@@H]1CCN(Cc2nc3ccccc3s2)C[C@@H]1F)C(=O)Cc4ccc(cc4)S(=O)(=O)C,2.1 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N2CC[C@H]3CCN(CCc4ccccc4)C[C@@H]23,2.47 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CN=C1c2ccc(F)cc2)N)C(=O)C(F)(F)F,1.05 | |
| Cc1cc(Nc2ccnc(NCc3onc(c3)C4CC4)n2)n[nH]1,2.5 | |
| COc1ccc2CCC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,.66 | |
| COc1cccc(c1)C(=O)NCCCOc2cccc3ccc(N)nc23,2.46 | |
| Cc1ccc(cc1)c2ccc(F)cc2COc3ccc(CCC(=O)O)cc3,3.24 | |
| CC[C@H](C)[C@H](N)C1=N[C@@H](CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(=O)N)NC(=O)[C@@H](CC(=O)O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC,-.46 | |
| COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(C)[C@@H](C)C(=O)N,3.42 | |
| OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1\C=C\C(=O)Nc3ccccc3,1.52 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)NCc3cccnc3)C(=O)C(F)(F)F,2.84 | |
| CC[C@H](NC(=O)c1c([S+]([O-])CC)c(nc2ccccc12)c3ccccc3)c4ccccc4,3.45 | |
| Nc1n[nH]c2c(Cl)cccc12,1.7 | |
| NC(=O)c1cccc(OC2CCN(CC3CC3)CC2)c1,.49 | |
| Cc1cc(CN2Cc3ccccc3C2C(=O)Nc4ccc(Cl)cc4)ccc1OCC(=O)O,1.38 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c(SC3CCCC3)c(Cc4ccccc4C(F)(F)F)sc12,4.21 | |
| OC(=O)[C@H](Cc1cccc(F)c1)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,2.68 | |
| CC1SC2=C(C(=O)O)C(=O)c3cc(F)c(cc3N12)N4CCN(CC5=C(C)OC(=O)O5)CC4,.47 | |
| CN([C@H]1CCN(Cc2ccc(cc2)C(F)(F)F)C[C@H]1F)C(=O)Cc3ccc(cc3)n4cnnn4,3.3 | |
| CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(c(F)c2)n3cc(nn3)C#N,.8 | |
| COC(=O)c1ccc2OCC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,.83 | |
| Clc1ccc2OCOc2c1Nc3ccnc(Nc4ccccc4)n3,3.9 | |
| COc1cc(OC2CCN(C)CC2)c3c(Nc4c(Cl)ccc5OCOc45)ncnc3c1,2.98 | |
| Cc1cc(CN2Cc3ccccc3C[C@H]2C(=O)Nc4ccc(Cl)cc4Cl)ccc1OCC(=O)O,2.41 | |
| Oc1ccc(cc1)C2=Cc3ccc(O)cc3OC2,3.8 | |
| OB(O)c1ccccc1C=O,.83 | |
| O=C(N1CC(=O)Nc2ccccc12)c3occc3,1.21 | |
| Oc1ccc(CCNCCCS(=O)(=O)NCCOCCc2ccc(F)cc2)c3sc(O)nc13,1.57 | |
| CCN(C1CCN(CC[C@H](c2ccc(cc2)S(=O)(=O)C)c3cc(F)c(F)c(F)c3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,2.55 | |
| C[C@@H]1CN(CCN1c2ncc(OCC3CCN(CC3)S(=O)(=O)C)cn2)C(=O)OC(C)(C)C,3.5 | |
| O=C1C=CN=C2C=CC=CN12,.2 | |
| O[C@@H]1CN(CCN2C(=O)C=Cc3ccc(cc23)C#N)CC[C@@H]1NCc4ccc5OCC(=O)Nc5n4,.11 | |
| CNC(=O)c1ccc2C(=O)C=C(Nc2c1)c3cccnc3,1.01 | |
| Clc1n[nH]c2cccc(Nc3ccnc(Nc4cc(cc(c4)N5CCOCC5)N6CCOCC6)n3)c12,2.78 | |
| Nc1ccccc1NC(=O)c2ccc(cc2)c3ncc(CN4CCCCC4)s3,2.82 | |
| COc1cc(ccc1OC[C@H](OP(=O)(O)O)C2CC2)N3C=Nc4cc(sc4C3=O)c5ccc(Cl)cc5,-.04 | |
| CCCC(=O)Nc1ccc(Cl)c(c1)c2oc3cccnc3n2,3.37 | |
| O=C(Nc1cccc(c1)c2nnn[nH]2)c3cccc4[nH]cnc34,-.05 | |
| Cc1c(Sc2ccc(Cl)cc2)c3cc(ccc3n1CC(=O)O)S(=O)(=O)C,.54 | |
| Cc1ccc2c(c1)c(c(C)n2CC(=O)O)S(=O)(=O)c3ccc(Cl)cc3,.06 | |
| CCC1(CCCCN(C)C1)c2cccc(O)c2,.8 | |
| COc1ccc(cc1)S(=O)(=O)NC2=CC=C(N(CC(=O)NC(C(C)C)C(=O)C(F)(F)F)C2=O)c3ccccc3,2.5 | |
| COc1cc(OC)c(cc1NC(=O)CCC(=O)O)S(=O)(=O)N2c3ccccc3Oc4ccccc24,-.53 | |
| Oc1ccc(CCNCCCS(=O)(=O)NCCOCCc2cccc(c2)C(F)(F)F)c3sc(O)nc13,2.62 | |
| CCCSc1nc2ccc(NC(=O)CCNC(=O)N)cc2s1,2.9 | |
| CC(C)C[C@H](CO)Nc1nc(S[C@@H](C)c2ccccc2)nc3NC(=O)Sc13,4.3 | |
| CCC(N1NC(=O)c2nc3cc(Cl)ccc3c(O)c2C1=O)c4cccnc4,.7 | |
| COc1cc(Nc2cc(nc(N[C@@H](C)c3ncc(F)cn3)n2)N4CCOCC4)n[nH]1,2.18 | |
| NC(=O)c1ccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)c(F)c1,2.1 | |
| CN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)Cc4ccc(Cl)cc4,3.5 | |
| Nc1ncccc1NCc2cccc(c2)c3cccnc3,3 | |
| Clc1ccc(NC(=O)N2CCN(C[C@@H]3CCCN(C3)C4CC4)CC2)cc1Cl,3.57 | |
| Nc1nnc(CCSCCc2nnc(N)s2)s1,-.1 | |
| CNc1cccc(CCOc2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2F)n1,-.05 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)N4CCN(CC4)C(=O)C)n2,2.39 | |
| CN1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c6oc(cc6)S(=O)(=O)C)c3C1=O,2.71 | |
| COCCC(=O)NC(C)c1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,2.98 | |
| CC(C)Cc1ccc(cc1)[C@@H](C)C(=O)NS(=O)(=O)C,.51 | |
| COC(=O)CCCCCCC(=O)Nc1ccc2C(=O)C(=O)c3ccccc3c2c1,2.6 | |
| Oc1cc(O)c2C(=O)C(=COc2c1)c3ccc(F)cc3,3.6 | |
| CC(=O)Nc1cnc2ccn(c3cc(NC4CC4)n5ncc(C#N)c5n3)c2c1,2.69 | |
| CC[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1S(=O)(=O)c3ccccc3,.44 | |
| C(Cc1nc2ccccc2[nH]1)c3nc4ccccc4[nH]3,3.3 | |
| CC[C@H](CO)Nc1nc(SCc2ccccc2)nc3NC(=O)Sc13,3.22 | |
| O[C@]1(CN2CCC1CC2)C#Cc3ccc(Oc4ccc(cc4)C(=O)NC5CCS(=O)(=O)C5)cc3,1.64 | |
| COc1cc(cc(OC)c1OC)C(=O)Nc2cc(NC(=O)c3cccc(c3)N(C)C)ccc2C,2.54 | |
| Fc1cccc(COc2cc(OCCCN3CCCC3)ccc2C(=O)Nc4ccccc4)c1,3.67 | |
| C[C@H](NC(=O)c1c(NS(=O)(=O)c2ccc(C)cc2)n(nc1C(F)(F)F)c3ccccc3)C(C)(C)C,2.35 | |
| NC(=O)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c3ncnc(N)c13,-.87 | |
| COc1ccc(Oc2ncccc2C(=O)NCc3ccccc3Cl)cc1,3.59 | |
| COc1cc2ncc(C(=O)N)c(Nc3ccccc3F)c2cc1OC,2.81 | |
| CC(C)NCCCOc1ccc(NC(=O)C)cc1CC=C,-.01 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(cc3)N4CCOCC4)ncc2F,3.01 | |
| CN(C)C(=O)c1ncc(Oc2cc(cc3oc(C)cc23)C(=O)Nc4cnc(C)cn4)cn1,2.1 | |
| C(=C\c1c(nc2sccn12)c3ccccc3)/c4ccncn4,3.4 | |
| CCOc1ccc(cc1)N2C(=Nc3ccccc3C2=O)CC,3.27 | |
| CCCc1c(O)c(ccc1OCCCSc2ccc(CC(=O)O)cc2Cl)C(=O)CC,3.57 | |
| CC1=NC(=C(NC1=O)c2ccc(CN3CCC(CC3)N4C(=O)Nc5ccccc45)cc2)c6ccccc6,3.9 | |
| ON(C=O)C1(CS(=O)(=O)N2CCN(CC2)c3ccc(F)cc3)CCC1,1.34 | |
| O=C(Nc1ccccn1)c2ccc3[nH]c(nc3c2)c4ccc(NC(=O)C56CC7CC(CC(C7)C5)C6)cc4,4.24 | |
| Nc1ccccc1NC(=O)c2ccc(CNc3nccc(n3)c4cccnc4)cc2,2.28 | |
| CCCSc1nc(N[C@@H]2C[C@H]2c3ccccc3)c4nnn([C@@H]5C[C@@H]([C@@H](O)[C@H]5O)C(=O)N)c4n1,2.05 | |
| COc1ccc2nc(C)cc(c2c1)n3cc(CN4CCN(CC4)C(=O)C)nn3,1.3 | |
| C1NCC(CC=C1)c2ccc3ccccc3c2,1.64 | |
| C(Cc1ccccc1)NCc2ccccc2,1.65 | |
| CCC1(C(=O)NC(=O)NC1=O)c2ccccc2,.05 | |
| O[C@@]1(CN2CCC1CC2)C#Cc3ccc(Oc4ccc(cc4)C(=O)NCc5ccncn5)cc3,1.77 | |
| CN1CCN(CC1)c2ccc3N=CN(C(=O)c3c2)c4cc(NC(=O)c5ccccc5F)ccc4C,2.75 | |
| Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O,3.06 | |
| CCn1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2OC)cn1,3.42 | |
| COCCNS(=O)(=O)c1ccc(Nc2nccc(n2)c3cnc4cccnn34)cc1,2.8 | |
| Cc1c(Sc2ccc(Cl)cc2)c3c(cccc3n1CC(=O)O)c4ccccc4,2.61 | |
| CN(c1ccnc(Nc2cc(cc(c2)S(=O)(=O)C)N3CCOCC3)n1)c4cc(CO)ccc4C,2.9 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CN=C1c2ccc(F)cc2)NC(=O)OCc3ccccc3)C(=O)C(F)(F)F,2.47 | |
| Cc1nocc1C(=O)Nc2ccc(c(N)n2)c3ccccc3OC(F)(F)F,3.7 | |
| CC1(COc2cc(ccc2NC(=O)CN3CCOCC3)c4cccc5C(=O)C=C(Oc45)N6CCOCC6)COC1,2.2 | |
| Oc1ccc(cc1)c2nc3ccccc3nc2c4ccc(O)cc4,2.7 | |
| Clc1cnc(OC2CCNCC2)cc1C(=O)NCC34CC5CC(CC(C5)C3)C4,1.56 | |
| Cc1nc(C)c(nc1C(=O)N)c2ccc(cc2)C34CCC(CC(=O)O)(CC3)CC4,1.6 | |
| Oc1ccc(C(=O)Cc2ccccc2)c(O)c1,3.09 | |
| C(N1CCN(CC1)c2nc3ccccc3s2)c4nnnn4Cc5cccs5,3.65 | |
| N[C@@H]1CCCN(C1)c2c(\C=C\3/SC(=O)NC3=O)cccc2c4ccncc4,1.56 | |
| Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1NC(=O)c3cccnc3,3.11 | |
| CCCN(CCC)C(=O)c1cccc(c1)C(=O)N[C@@H](Cc2ccccc2)[C@H](O)CNC3Cc4ccccc4C3,3.3 | |
| OC(=O)c1ccc2cccc(O)c2n1,3.3 | |
| CC1=CC2=NNC(=O)N2c3cc(ccc13)c4ccc(cc4)C(=O)N5CCOCC5,2.77 | |
| Nc1[nH]nc2ccccc12,1 | |
| CS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)c3ccc(F)cc3,1.5 | |
| CCCCCSc1nc(O)c2sc(N)nc2n1,2.86 | |
| CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(c(F)c2)n3cnc(c3)C#N,1.51 | |
| COc1ncccc1c2cccc3c(N)c4C(=O)N(Cc4nc23)C5CCC5,3.26 | |
| COCCC(C)n1nc(C)c(C(=O)N[C@@H](C)C(C)(C)C)c1NS(=O)(=O)c2ccc(C)cc2,.78 | |
| Nc1ccccc1NC(=O)c2ccc(cc2)C3CCN(Cc4ccccc4)CC3,2.51 | |
| CC(C)C[C@H](CO)Nc1nc(SCc2ccncc2)nc3nc(N)sc13,2.9 | |
| CCCC1=CC(=O)NC(=S)N1,.7 | |
| O=C1N2CCOC2=Nc3ccccc13,.6 | |
| NC(=O)c1cc(cc(c1)[N+](=O)[O-])[N+](=O)[O-],.81 | |
| NC(=O)COc1ccc(OCCNCC(O)COc2ccccc2)cc1,.63 | |
| COc1ccc(OC)c(c1)c2cccc3c(N)c(nnc23)C(=O)NC4(C)CCC4,4.48 | |
| CCC1(C)CC(=O)NC1=O,.23 | |
| NC(=O)c1ccn2c(c3ccccc3)c(nc2c1)c4ccc(cc4)C5(N)CCC5,2 | |
| CC1=CC2=NNC(=O)N2c3cc(ccc13)c4ccc[nH]4,3.29 | |
| CC(C)N1CCN(Cc2cnc(c(F)c2)c3ccc(cc3)C(=O)Nc4ccccc4N)CC1,1.6 | |
| CN([C@@H]1CCN(Cc2ccc(cn2)C(F)(F)F)C[C@@H]1F)C(=O)Cc3ccc(cc3)n4cnnn4,2.1 | |
| CCCCCC\N=C\1/C=CN(Cc2ccccc2)c3cc(Cl)ccc13,.98 | |
| CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O,-1.1 | |
| OC(=O)CC(=O)N[C@H]1[C@@H](Cc2ccccc12)NC(=O)c3cc4sc(Cl)c(Cl)c4[nH]3,1.18 | |
| Nc1nc2ccccc2s1,2 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)C(=O)NCCO)n2,2.09 | |
| Cc1ccc(F)c(Nc2ccnc(Nc3ccc(cc3)S(=O)(=O)N)n2)c1,3.1 | |
| CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O,1.69 | |
| FC(F)(F)c1nnc2ccc(nn12)n3ccnc3,.91 | |
| CCOC(=O)c1ccc(CCN2CCN(CC2)c3ccc(C)nn3)cc1,2.58 | |
| Cc1cc(ccn1)c2ccc(cc2)c3nc4ccncc4c(O)c3C#N,1.6 | |
| Cn1cnc(c2ccccc2)c1\C=C\c3ccnc(N)n3,2.61 | |
| Cc1cc(C)c(C(=O)N[C@@H](Cc2ccc(OCCCNc3ccccn3)cc2)C(=O)O)c(C)c1,.49 | |
| COc1cc2ncc(C(=O)N)c(Nc3ccc(F)c(Cl)c3)c2cc1OC,3.22 | |
| OC(=O)c1cc(nc2ccccc12)c3ccccc3,-.7 | |
| N[C@H]1CCN(C1)c2c(Cl)cccc2\C=C\3/SC(=O)NC3=O,1.89 | |
| OC(=O)c1ccccc1c2ccc(Cl)c(c2)C(=O)NCC3(O)CCCCCC3,-.34 | |
| CC(C)N1CCN(CC1)C(=O)NCc2ccc(Cl)c(Cl)c2,2.75 | |
| C[C@H](N1CCC[C@@H](C1)N2C=C(C)C(=O)NC2=O)c3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3,-.26 | |
| COc1ccc(N(C(C(=O)NC[C@@H](C)O)c2ccccc2F)C(=O)c3occc3CO)c(OC)c1,1.37 | |
| NC1(CCC1)c2ccc(cc2)c3ncc4cccn4c3c5ccccc5,2.5 | |
| NC(Cc1ccc(cc1)N(CCCl)CCCl)C(=O)O,.39 | |
| CC(C)Nc1nc(NCc2ccccc2)c3sccc3n1,3.9 | |
| CNS(=O)(=O)c1ccc(Oc2ccc(cc2)C#C[C@]3(O)CN4CCC3CC4)cc1,2.03 | |
| Cc1ccc(Oc2ccnc(Nc3ccc(cc3)S(=O)(=O)N)c2)c(C)n1,2.47 | |
| CCOC(=O)c1ccc(COCC2CCN(CC2)c3ccc(C)nn3)cc1,2.68 | |
| Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1,2.54 | |
| Cc1cc(Oc2ccnc(Nc3ccc(cc3)N4CCOCC4)c2)c(nc1C)c5ccccn5,2.59 | |
| CS(=O)(=O)c1ccc2C(=CNC(=O)c2c1)C(=O)NC[C@@H](O)CN3CCC(CC3)Oc4ccc(C#N)c(Cl)c4,1.41 | |
| C[C@H]1O[C@H]([C@H](O)[C@H]1Cl)n2cnc3c(N)nc(OC4CCCC4)nc23,3.18 | |
| Nc1ncnc2[nH]ccc12,1.78 | |
| Fc1cc(Oc2ccc(cc2c3ccnnc3)C(F)(F)F)c(Cl)cc1S(=O)(=O)Nc4nncs4,1.15 | |
| NC(=O)c1cccc(O[C@@H]2C[C@H]3CC[C@@H](C2)N3CCc4ccccc4)c1,2 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(cc3)C(=O)N)ncc2F,2.7 | |
| Clc1ccc2[nH]ncc2c1,2.44 | |
| CN1CCN(CC1)C(=O)c2cc3ccccc3[nH]2,1.7 | |
| NC(=O)c1cccc(S[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)c1,2.22 | |
| NC(=O)C[S+]([O-])C(c1ccccc1)c2ccccc2,1.12 | |
| CC(=O)Nc1ccc(CNc2[nH]nc3ccnc(Oc4ccccc4)c23)cc1,3.03 | |
| NC(=N)N1CCc2ccccc2C1,-1.01 | |
| NC(=O)c1c(NC(=O)NCCCCN2CCCC2)snc1OCc3c(F)cc(Br)cc3F,2.5 | |
| O=S(=O)(C1CCNCC1)C2(CC2)c3cc(nc(n3)c4cccc5[nH]ccc45)N6CCOCC6,1.1 | |
| Cc1ccc2c(c(C)n(CC(=O)O)c2c1)c3ccnc4cc(Cl)ccc34,2.41 | |
| CN(c1ccc2c(C)n(C)nc2c1)c3ccnc(Nc4ccc(C)c(c4)S(=O)(=O)N)n3,3.3 | |
| Cc1ccc2nc(NCCN)c3ncc(C)n3c2c1,.88 | |
| CNC(=O)c1ccc(C)c(c1)N2C(=CC(=C(Br)C2=O)OCc3ccc(F)cc3F)C,2.8 | |
| Oc1ccc(Cl)cc1C(=O)Nc2ccccc2,2.9 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3ccnc4ccccc34)c2C(=O)N5C[C@@H](O)[C@@H](O)C5,1.18 | |
| O=C1N([Se]c2ccccc12)c3ccccc3,3.31 | |
| COc1ccc2C=CC(=O)N(CCN3CCC(CC3)NCc4cc5OCCOc5cn4)c2c1,1.31 | |
| CC(C)COc1cc(OC(C)C)cc(c1)C(=O)Nc2ccc(cn2)C(=O)O,1.6 | |
| Clc1ccc2NC(=O)CN(C(c3ccccc3)c2c1)C(=O)c4ccccc4,3.31 | |
| CNC(=O)c1ccc(Nc2nccc(n2)c3cnc(C4CC4)n3C(C)C)cc1,2.77 | |
| CC(C)CC(N1NC(=O)c2nc3cc(Cl)ccc3c(O)c2C1=O)c4ccccn4,1.83 | |
| CC(C)C[C@H](NC(=O)N1CCOCC1)C(=O)N[C@@H](CCc2ccccc2)\C=C\S(=O)(=O)c3ccccc3,3.4 | |
| O=C(CN1CCOCC1)Nc2c(cnn2c3ccccc3)C#N,.5 | |
| CC1=C(C(=O)c2cc(O)c(O)c(CCc3ccc(C)cc3)c2C1=O)C4=C(C)C(=O)c5c(CCc6ccc(C)cc6)c(O)c(O)cc5C4=O,3.36 | |
| CCN(CC)CC(=O)Nc1c(cnn1c2ccccc2)C#N,.4 | |
| CCN1CCN(CC(=O)Nc2ccc(c3cccc4C(=O)C=C(Nc34)N5CCOCC5)c6sc7ccccc7c26)CC1,2.6 | |
| CCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C,3.3 | |
| CCCC(C)(COC(=O)N)COC(=O)NC(C)C,2.01 | |
| CC(=O)Nc1ccc(O)cc1OC[C@@H](O)CN2CCC3(CC2)Cc4cc(Cl)ccc4O3,2.76 | |
| [O-][N+](=O)c1ccc2[nH]ncc2c1,2.2 | |
| Cc1cc(C)cc(c1)c2[nH]c3ccccc3c2CCNCCCCc4ccncc4,3.3 | |
| COC(CN1C(=O)NC2=C(C=C(N(CC(=O)NC(C(C)C)C(=O)C(F)(F)F)C2=O)c3ccccc3)C1=O)OC,1.56 | |
| O=S(=O)(Cc1ccccc1)NCC(N2CCCCCC2)c3ccccc3,2.83 | |
| CCOC(=O)Nc1ccc2Sc3ccccc3N(C(=O)CCN4CCOCC4)c2c1,3.1 | |
| OC(=O)[C@H](Cc1ccccc1C#N)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,2.12 | |
| Cc1ccc(C)c(OCCCC(C)(C)C(=O)O)c1,.72 | |
| O=S(=O)(NCC(N1CCCCCC1)c2ccccc2)c3cccnc3,2.1 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)N,2.4 | |
| O=S(=O)(Nc1cccnc1)c2ccccc2,.84 | |
| COC(=O)[C@@H]1C2CCC(C[C@@H]1c3ccc(I)cc3)N2CCCF,2.3 | |
| COCCOc1cc2nccc(Nc3cc(O)c(Cl)cc3F)c2cc1OC,2.64 | |
| CC(C)N1CCN(Cc2cnc(c3ccc(cc3)C(=O)Nc4ccccc4N)c(c2)C#N)CC1,1.28 | |
| O=C(Nc1oc(nn1)C(=O)Nc2ccc(cc2)N3CCOCC3)c4ccccc4,1.02 | |
| Cc1ccc(cc1)n2nc(cc2NC(=O)Nc3ccc(OCCN4CCOCC4)c5ccccc35)C(C)(C)C,4.49 | |
| COc1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cc1OCCCN4CCN(C)CC4)C(=O)N,1.2 | |
| Cn1cnc2cc(cnc12)C#Cc3ccccc3,3.5 | |
| C[C@H](Nc1ncc(F)c(Nc2cc([nH]n2)N(C)C)n1)c3ncc(F)cn3,1.98 | |
| O=C1C2=Nc3ccccc3CN2c4ccccc14,2.71 | |
| CCNC1=CC=C(N(CC(=O)NC(C(C)C)C(=O)C(F)(F)F)C1=O)c2ccccc2,2.37 | |
| Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(F)c(F)c4,.75 | |
| C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc3NC(=O)C(=O)Nc13,2.48 | |
| COc1ccc(Cl)cc1NC(=O)Nc2cnccn2,3.63 | |
| CCOC(=O)Nc1cccc(c1)[C@H](N2CCN(Cc3c[nH]c(C)n3)CC2)c4ccc(cc4)C(=O)N(C)CC,2.11 | |
| Cc1ccc(NC(=O)c2ccc(Cl)c(c2)C(F)(F)F)cc1C(=O)Nc3cccnc3,2.83 | |
| CNc1cccc(CCOc2ccc(C[C@H](NC(=O)c3c(F)cccc3Cl)C(=O)O)cc2)n1,-.42 | |
| NCc1ccc(NC(=O)c2cc(Nc3ncccn3)c4cc(ccc4c2)\C(=N\O)\N)cc1,-.85 | |
| CCS(=O)(=O)c1cccc(c1)c2cc(ccc2OCC(=O)O)C(F)(F)F,-.66 | |
| CCOc1cc2ncc(C(=O)N)c(Nc3ccc(F)cc3F)c2cc1N4CCC(O)CC4,2.74 | |
| CN1CCN(CC1)c2cc3c(Nc4ccc(F)cc4F)c(cnc3cc2F)C(=O)N,2.63 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4ccccn34)N5CC6CN(CCO)CC(C5)O6,2.5 | |
| NC1(CCC1)c2ccc(cc2)c3nn4ccccc4c3c5ccccc5,3.2 | |
| CN(C)C(=O)N[C@@H]1CC[C@H](CCN2[C@@H]3CC[C@H]2C[C@H](C3)Oc4cccc(c4)C(=O)N)CC1,.22 | |
| COCCNC(=O)c1ccc(Nc2ncc3cc(ccc3n2)c4cccnc4)cc1,3.11 | |
| CCOC(=O)c1ccc(OCCC2CN(C2)c3ccc(C)nn3)cc1,3.22 | |
| OC1CCN(CC1)C(=O)[C@H](Cc2ccccc2)NC(=O)c3cc4cc(Cl)ccc4[nH]3,3.6 | |
| C=CCOc1cc(ccc1NC(=O)CN2CCOCC2)c3cccc4C(=O)C=C(Oc34)N5CCOCC5,3 | |
| Cc1cccc(n1)C#Cc2ccccc2,3.6 | |
| CCN(C1CCN(CCC(C2CCN(CC2)S(=O)(=O)CC)c3ccccc3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,1.63 | |
| CCc1cccc2c(cn(CC(=O)NCCOC)c12)C#N,1.95 | |
| COc1cccc2sc(NC(=O)c3ccccc3)nc12,3.96 | |
| Nc1nc(nn1Cc2ccccc2)c3ccccc3,1.91 | |
| COc1ccc2OCC(=O)N(CCN3CCC(CC3)NCc4cc5OCCOc5cn4)c2c1,1.24 | |
| CC(NC(=O)c1cc(O)nc2ccccc12)c3ccccc3,2.2 | |
| COc1ccnc(c1)N(C)c2ccnc(Nc3cc(cc(c3)N4CCOCC4)N5CCOCC5)n2,2.23 | |
| Nc1nc(OC2CCCC2)nc3c1ncn3[C@@H]4O[C@H](CF)[C@@H](O)[C@H]4O,1.5 | |
| Oc1oc(c2ccccc2)c(n1)c3ccccc3,3.42 | |
| COc1ccc(\C=C/2\CCc3ccccc3C2=O)cc1CN4CCOCC4,3.8 | |
| CC(C)(C)c1ccc(cc1)C(O)CCCN2CCC(CC2)C(O)(c3ccccc3)c4ccccc4,3.99 | |
| NC(=O)c1cnc(N[C@H]2CCCNC2)c3cc(sc13)c4ccc(F)c(F)c4,2.17 | |
| O[C@@H](CNCCCOCCOCCc1ccccc1)c2ccc(O)c3NC(=O)Sc23,1.09 | |
| FC(F)(F)c1cccc(C(=O)N[C@H]([C@@H]2CCCCN2)c3ccccc3)c1Cl,2.61 | |
| COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(Cl)c(c2)c3nc4ccccc4[nH]3,3.83 | |
| FC(F)(F)c1csc(n1)N2CCN(CC2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NC4(CC4)C#N,2.4 | |
| CC(C)Nc1nc(nc(N2CCOCC2)c1N)C#N,2.04 | |
| O=C1NC=Cc2nc(c3ccc(CN4CCC(CC4)c5n[nH]c(n5)c6ccccn6)cc3)c(cc12)c7ccccc7,3.9 | |
| Cc1cc(N)nc(CCNC(=O)c2ccc(cc2)C#N)c1,1.62 | |
| CCNC1=Nc2ccccc2C(=NC1c3cccs3)c4ccccc4,3.98 | |
| Cc1ccc(c(C)c1)c2nnc(O)c3ccccc23,3.41 | |
| Fc1ccc(cc1)N2CCN(CC2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NC4(CC4)C#N,2.12 | |
| Cc1nc(nc(N2CCCC2)c1Cl)c3ccccn3,3.2 | |
| C[C@@H](NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4ccc(Cl)cc4,3.3 | |
| COc1ccc(Cl)c(c1)C(=O)NCC23CC4CC(CC(C4)C2)C3,4.39 | |
| C[C@@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)C[C@H](C)N1C(=O)Cc3ccccc3,.7 | |
| Cc1ccc(cc1)C(=O)N(CCCN)CC2=Nc3cc(Cl)ccc3C(=O)N2Cc4ccccc4,1.47 | |
| O=C(NCC#N)[C@@H]1CCCC[C@H]1C(=O)N2CCc3ccccc3C2,1.91 | |
| COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC,3.35 | |
| CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]4CCOC4,3.7 | |
| CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1CCCN(CCc2ccc(O)cc2)C1)C(C)(C)C,.77 | |
| CCOC(=O)c1ccc(OCC2CCN(C2)c3ccc(C)nn3)cc1,3.44 | |
| OC(=O)[C@H](Cc1ccc(OCCc2ccc3OCCNc3n2)cc1)NC(=O)c4c(Cl)cccc4Cl,-.18 | |
| O.O.O.CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]3(C)[C@@H]2[C@H](OC(=O)c4ccccc4)[C@]5(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c6ccccc6)C(=C([C@@H](O)C3=O)C5(C)C)C,3.4 | |
| [O-][S+](CCC1C(=O)N(N(C1=O)c2ccccc2)c3ccccc3)c4ccccc4,-.51 | |
| COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC,2.81 | |
| COc1ccc(C)c(c1)N(C)c2ccnc(Nc3cc(cc(c3)N4CCOCC4)N5CCOCC5)n2,3.18 | |
| Clc1ccc(CN(Cc2ccc(Cl)cc2)c3nn[nH]n3)cc1,2.74 | |
| Cc1c(F)ccc2c1c(Sc3ccc(Cl)cc3)c(C)n2CC(=O)O,2.23 | |
| CN(c1ccnc(Nc2cc(cc(c2)N3CCOCC3)N4CCOCC4)n1)c5cc(CO)ccc5C,2.94 | |
| Nc1n[nH]c(N)c1Cc2ccc3OCOc3c2,.47 | |
| CCCCSc1nc(N)c2ncn(Cc3c(F)ccc(C)c3F)c2n1,3 | |
| COc1ccc(cc1CNCCO)c2ccc3c(nc(nc3n2)N4C[C@@H](C)O[C@@H](C)C4)N5CCOCC5,1.31 | |
| OC(=O)c1cc2ccccc2n1Cc3ccccc3,.78 | |
| COc1cccc(c1)C(COCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)N3CCNCC3,3.1 | |
| Nc1ccc2C(=O)C(=O)c3ccccc3c2c1,2.39 | |
| Cc1cc(CNc2ncc(Br)c(Nc3cc(C)[nH]n3)n2)on1,2.92 | |
| COc1ccc(CCN2CNC(=NC2)SCc3ccc(Cl)cc3)cc1OC,2.41 | |
| Clc1ccc(NC(=O)N2CCN(C[C@@H]3CCCN(Cc4ccccc4)C3)CC2)cc1Cl,4.26 | |
| CC(=O)Nc1nc(ns1)c2ccccc2,2.8 | |
| OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc(cc1)[N+](=O)[O-],1.15 | |
| NS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)c3ccc(F)cc3,1.95 | |
| O[C@@H](CNCCSCCCNCCc1cccc(Cl)c1Cl)c2ccc(O)c3NC(=O)Sc23,2.2 | |
| C[C@@](Cc1ccc(O)c(O)c1)(NN)C(=O)O,-.7 | |
| CC(=O)Nc1cccc2c1c(Oc3ccc(Cl)cc3)c(C)n2CC(=O)O,-1.41 | |
| COC[C@H](C)Oc1cc(Oc2ccc(cc2)S(=O)(=O)C)cc(c1)C(=O)Nc3ccc(cn3)C(=O)O,-.41 | |
| CC1=C(CCN2CCC(CC2)c3noc4cc(F)ccc34)C(=O)N5CCCCC5=N1,2.05 | |
| Cc1nc(CS(=O)(=O)c2ccc(Cl)cc2)cc(n1)N3CCOCC3,1.8 | |
| COc1c(N2CCNC(C)C2)c(F)cc3C(=O)C(=CN(C4CC4)c13)C(=O)O,-.82 | |
| OC(=O)[C@H](Cc1ccc(F)cc1)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)cc4)CC2,1.9 | |
| COc1ccc2nc(C)cc(OCC(=O)Nc3ccccc3OC)c2c1,3.9 | |
| CCN(CC)C(=O)c1ccc(cc1)C(=C2CCN(Cc3ccc(F)cc3)CC2)c4ccccn4,3.28 | |
| CCCCCCCN(CC)CCCC(O)c1ccc(NS(=O)(=O)C)cc1,1.2 | |
| CC(NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4ccc(Cl)cc4,2.7 | |
| C[C@]12CCC(=O)C=C1C=C[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CC[C@@]45CCC(=O)O5,3.2 | |
| Cc1ccc2c(c1)c(Sc3cccc(Cl)c3)c(C)n2CC(=O)O,1.85 | |
| COc1ccc2c(C)nc(NC(=N)N)nc2c1,-.51 | |
| CC[C@H](NC(=O)c1c(O)c(nc2ccccc12)c3ccccc3)c4ccccc4,3.91 | |
| Fc1ccc(CNc2ncc(Br)c(Nc3cc([nH]n3)C4CC4)n2)cc1,4.28 | |
| OC(=O)COc1ccc(cc1c2ccc(Cl)cc2)C(F)(F)F,.9 | |
| COCCCc1cc(Nc2ccnc(NCc3onc(C)c3)n2)n[nH]1,2.04 | |
| CC(O)(C(=O)c1ccccc1)c2ccccc2,2.92 | |
| C[C@@H](c1ncncc1F)[C@](O)(Cn2cncn2)c3ccc(F)cc3F,1.7 | |
| Clc1ccc(OC2CCN(CC2)C3CCN(CC3)C(=O)c4ccc(cc4)C5=NOC(=O)N5)cc1Cl,2.24 | |
| COc1cc(CO)cc(c1)N(C)c2ccnc(Nc3cc(cc(c3)N4CCOCC4)N5CCOCC5)n2,3 | |
| CC(C)NC(=O)c1c(C)nn(c1NS(=O)(=O)c2ccc(C)cc2)c3ccccc3,.46 | |
| CN1CCC[C@H]1CCN2CCCc3cc(NC(=N)c4cccs4)ccc23,.37 | |
| COC1=CC=C2C(=CC1=O)C(CCc3cc(OC)c(OC)c(OC)c23)NC(=O)C,1.12 | |
| Cc1ccc(CN2[C@@H]3CC[C@H]2C[C@H](C3)Oc4cccc(c4)C(=O)N)s1,2.39 | |
| OB1N(C(=Nc2ccccc12)S)c3cccnc3,-.62 | |
| COc1ccccc1CCNCc2cccc(CCNC[C@H](O)c3ccc(O)c4NC(=O)Sc34)c2,.82 | |
| Cn1c(C(=O)O)c(CCCOc2cccc3ccccc23)c4ccccc14,2.99 | |
| O=S(=O)(c1ccccc1)C2(CC2)c3cc(nc(n3)c4cccc5[nH]ccc45)N6CCOCC6,3.4 | |
| FC(F)(F)c1ccc(cc1)S(=O)(=O)NCC(N2CCCCCC2)c3ccccc3,4.29 | |
| CS(=O)(=O)c1ccc(C(=O)Nc2ccc(Cl)c(c2)c3ccccn3)c(Cl)c1,2.84 | |
| Cc1nc(N)c2nc(O)n(Cc3ccccc3)c2n1,2.04 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)Cc4ccc(cc4)C#N,3.9 | |
| O=C(Nc1ccccc1)c2ccccc2,2.8 | |
| CCC(CO)NCCNC(CC)CO,-1.42 | |
| CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1,-.33 | |
| CCN1CCO[C@@H](CN2CCN(CC2)C(=O)Nc3ccc(Cl)c(Cl)c3)C1,2.68 | |
| COC[C@H](N1CCN(C[C@@H]1C)C2(C)CCN(CC2)C(=O)c3c(C)ncnc3C)c4ccc(cc4)C(F)(F)F,2.7 | |
| COc1ccc(cc1OC)S(=O)(=O)Nc2ccc(\C=C\C(=O)Nc3ccccc3N)cc2,2.56 | |
| OC(=O)C(N1CCC(CC1)N2CCC(CC2)Oc3ccc(Cl)c(Cl)c3)c4ccccc4,2.23 | |
| C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)C)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]4(C)C=CC(=O)C=C14,2.65 | |
| Clc1ccccc1CNC(=O)c2ccccc2Oc3ccccc3,3.58 | |
| CC1(COc2ccc3c(c2)ncn3c4ccc5cccc(N6CCC(N)CC6)c5n4)COC1,1.99 | |
| OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c3ccc(Cl)cc3,2.67 | |
| C[C@H](NC(=O)c1c(C)nn(c1NS(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(C)(C)C,1.44 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)Cc3cccc(c3)C(=O)O)C(=O)C(F)(F)F,.68 | |
| OC(=O)CCC(=O)c1ccc(cc1)c2ccccc2,.58 | |
| CCCSc1c(cnn1[C@@H]2CC[C@@H](CC2)C(=O)O)C(=O)NC3CCCCC3,1.39 | |
| COc1cc(Nc2c(cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)C#N)c(Cl)cc1Cl,3.5 | |
| Nc1c(nnc2c(cccc12)c3ncccn3)C(=O)NC4CC4,1.5 | |
| C[C@H](NC(=O)c1c(C)nn(CC(F)(F)F)c1NS(=O)(=O)c2ccc(C)cc2)C(C)(C)C,.93 | |
| CC(C)(C)OC(=O)N1C[C@@H]2CC[C@H]1CN2c3ncc(OCc4ccc(cc4)S(=O)(=O)C)cn3,3.4 | |
| CC[C@@]1(O)C(=O)OCC2=C1C=C3N(Cc4cc5c(CN(C)C)c(O)ccc5nc34)C2=O,.31 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2CCCN(CCCc3ccccc3)C2,2.6 | |
| COc1cc2c(Nc3c(Cl)ccc4OCOc34)ncnc2cc1OCC5CCN(C)CC5,1.83 | |
| Clc1ccccc1CNC(=O)c2cccnc2Oc3ccccc3,3.68 | |
| NS(=O)(=O)c1cc(ccc1Cl)C2(O)NC(=O)c3ccccc23,.97 | |
| Cc1cc(OCCCS(=O)(=O)C)cc(C)c1c2cccc(COc3ccc4[C@H](CC(=O)O)COc4c3)c2,2.3 | |
| COc1ccc2nc(NC(=O)CCc3ccc(OC)c(OC)c3)sc2c1,3.57 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(C(=O)NCCN(C)C)c(F)c3)ncc2F,2.26 | |
| CN1CCN(CC1)C(=O)c2cc3cc(C)ccc3[nH]2,2.22 | |
| CNc1cccc(CCCc2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)O)s2)n1,.78 | |
| COc1cc(OC)c(cc1NC(=O)CCc2nn[nH]n2)S(=O)(=O)N3C(C)CCc4ccccc34,-.34 | |
| CCOC(=O)c1ccc(OCCC2CCN(CC2)c3ccc(C)nn3)cn1,2.63 | |
| CC(C)(C(=O)c1cccnc1)c2cccnc2,1.45 | |
| CNC(=O)c1ccc(Oc2ccc3CCN(CCc3c2)C4CCC4)nc1,1.45 | |
| CC(C)(C)OC(=O)N1CCN(CC1)c2ccc(OCc3ccc(cc3)S(=O)(=O)C)cn2,3.2 | |
| Fc1cccc(c1F)c2cncc(CNCC3CC3)n2,1.82 | |
| OC1N=C(c2ccccc2Cl)c3cc(Cl)ccc3NC1=O,2.38 | |
| CCCNC(=O)c1nnc2c(cccc2c1N)c3cncc(c3)C(=O)N4CCC4,2.79 | |
| CS(=O)(=O)c1cccc2c3CN(CCc3[nH]c12)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,1.7 | |
| CN(C)CCCNS(=O)(=O)c1ccc(Nc2nccc(n2)c3cnc4cccnn34)cc1,1.4 | |
| Nc1c2CCCCc2nc3ccccc13,.38 | |
| O=C(C1CCN(CC1)c2nnc(s2)n3cccc3)N4CCc5ccccc5C4,3.7 | |
| COc1ccc(CN2CCc3c(C2)[nH]c4ccccc34)cc1OC,3.1 | |
| CNC1=Nc2ncccc2C(=NC1c3cccs3)c4cccs4,2.63 | |
| Clc1ccc2NC(=O)CN(C(c3ccccc3)c2c1)C(=O)c4occc4,3 | |
| CC(C)CNc1nc(nc(NC2CCS(=O)(=O)C2)c1N)C#N,2.3 | |
| Cn1cc(nc1c2c3C(=O)N(CC#C)C(=O)N(CC4CC4)c3nn2Cc5ccnc6ccc(Cl)cc56)C#N,3.4 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4cc(F)ccn34)N5CCN(CC5)C(=O)C,3.7 | |
| O[C@]1(CN2CCC1CC2)C#Cc3ccc(Oc4ccc(cc4)C(=O)NCc5ccncn5)cc3,1.78 | |
| CN(C)CCNC(=O)c1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,2.29 | |
| CC1=CC2=NNC(=O)N2c3ccccc13,2.35 | |
| Cc1cc(c(S)cc1Cl)S(=O)(=O)Nc2nc(Nc3ccc(Cl)cc3)n[nH]2,2.09 | |
| CCCCC[C@@H](N1CCC[C@@H](C1)N2C=C(C)C(=O)NC2=O)c3ccc(C(=O)O)c(Oc4cccc(Br)c4)c3,1.69 | |
| CCC(N(CCCN)C(=O)c1ccc(C)cc1)C2=Nc3ccsc3C(=O)N2Cc4ccc(Cl)cc4,2.32 | |
| CN1CC(=O)N2[C@H](Cc3c([nH]c4ccccc34)[C@H]2c5ccc6OCOc6c5)C1=O,2.6 | |
| CCC(CC)NC(=O)c1cnn(c1NS(=O)(=O)c2ccc(C)cc2)c3ccccn3,.27 | |
| CC1=C(OCc2ccccc2)C(=O)C=CO1,1.87 | |
| O=C(CC12CC3CC(CC(C3)C1)C2)Nc4cccc5ncccc45,3.83 | |
| O=C1C(=O)c2cccnc2c3ccccc13,1.88 | |
| COc1ccccc1OCC(O)CO,.24 | |
| CNc1c(Br)cnc2[nH]c(nc12)c3cnn(c3)C4CCN(C)CC4,2.5 | |
| CN(CC[C@@H](Oc1ccc(cc1)c2ccccc2)c3ccc(F)cc3)CC(=O)O,2.86 | |
| CCc1cccc2c3CCOC(CC)(CC(=O)O)c3[nH]c12,.49 | |
| CS(=O)(=O)c1ccc(cc1)[C@H](CC2CCCC2)C(=O)Nc3nccs3,3.88 | |
| CN1CC(c2ccccc2)c3cccc(N)c3C1,2.08 | |
| Nc1cccc(NC(=O)c2ccc(CNC(=O)OCc3cccnc3)cc2)c1,1.6 | |
| CCc1c(cnn1c2ccc(cc2)C(=O)O)C(=O)NC3C4CC5CC(CC3C5)C4,.9 | |
| CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1,2.12 | |
| CCCSc1nc(N[C@@H]2CC[C@H](CC2)C(=O)O)ccc1C(=O)NC3CCCCC3,2.02 | |
| NC1(Cc2ccc(Cl)cc2)CCN(CC1)c3ncnc4[nH]ccc34,2.72 | |
| CC(C)CCCC(C)\N=C\1/C=CN(Cc2ccccc2)c3cc(Cl)ccc13,1.58 | |
| CC1=CC(=O)Oc2c3CCCNc3c(C)cc12,2.9 | |
| CC#Cc1cncc(c1)c2cccc(c2)C3(N=C(C)C(=N3)N)C4CC4,3.3 | |
| CN1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c6cncn6C)c3C1=O,2.69 | |
| NC(=O)c1cnc(N[C@H]2CCCNC2)c3cc(sc13)c4ccc(F)cc4,2.01 | |
| Cc1c(Sc2ccc(Cl)cc2)c3cccc(Cl)c3n1CC(=O)O,2 | |
| OC(CCN1CCCCC1)(C2CCCCC2)c3ccccc3,2.68 | |
| Fc1ccc(N2CCN(CC2)C(=O)COCc3ccncc3)c(Cl)c1,2.63 | |
| COc1cc(F)ccc1c2cncc(CNC[C@@H]3CCCO3)n2,2 | |
| Nc1ncnc2nc(cc(c3cccc(Br)c3)c12)c4ccc(nc4)N5CCOCC5,3.2 | |
| CC1=CN(Cc2ccccc2)C(=O)NC1=O,1.19 | |
| CCCCCC1=CC(=O)NC(=N1)N,1.62 | |
| C[C@H](NC(=O)c1c(C)nn(c1NS(=O)(=O)c2cccc(CN3CCOCC3)c2)c4ccccc4)C(C)(C)C,.29 | |
| Clc1ccc2C(=O)C3=C(Nc2c1)C(=O)NN(Cc4cocc4)C3=O,.6 | |
| O=C1CCOc2nc(COc3ccccc3)ccc12,2.3 | |
| Nc1nc2ccccc2n1C(=O)c3ccccc3,1.56 | |
| CC(C)c1nnc2ccc(cn12)c3ocnc3c4cc(F)ccc4F,2.44 | |
| CC(=O)N1CCN(CC1)c2ccc(OCC3COC(Cn4ccnc4)(O3)c5ccc(Cl)cc5Cl)cc2,3.7 | |
| CC1=CN([C@H]2CCCN(Cc3cccc(Oc4cccc(Br)c4)c3)C2)C(=O)NC1=O,3.68 | |
| COc1cc(ccc1Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)N4CCN(C)CC4,3.9 | |
| CCN(C1CCN(CC[C@H](c2ccc(cc2)S(=O)(=O)C)c3cccc(Cl)c3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,2.37 | |
| CCn1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(F)ccc34)cc2OC)cn1,3.93 | |
| COc1cc(F)ccc1c2cncc(CNC(=O)C3CC3)c2,2.9 | |
| Cn1cc(cc1c2c3C(=O)N(CC=C)C(=O)N(CC4CC4)c3nn2Cc5ccnc6ccc(Cl)cc56)C#N,4.27 | |
| O=C(NCC#N)c1ccc(cc1)c2ccnc(Nc3ccc(cc3)N4CCOCC4)n2,2.37 | |
| CNC(=O)C1(CCN(CC[C@H](CN(C)C(=O)c2cc(cc3ccccc23)C#N)c4ccc(Cl)c(Cl)c4)CC1)N5CCCCC5=O,2.5 | |
| O[C@@H]1CNC[C@H]1N2C=Cc3c(NC(=O)Cc4ccc(F)c(c4)C(F)(F)F)cccc3C2=O,1.33 | |
| CC(C)OC(=O)N1CCC(CC1)Oc2ncnc(Oc3cccnc3C)c2C,3.8 | |
| Cc1ncc2CN=C(c3ccccc3F)c4cc(Cl)ccc4n12,3.4 | |
| CCN(C1CCN(CC[C@H](C2CCN(CC2)S(=O)(=O)C(F)(F)F)c3ccccc3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,3.39 | |
| CN1C(=O)c2c(onc2c3ccncc3)C=C1c4ccccc4,3.17 | |
| Cc1cc(N)n(n1)c2ccccc2,1.25 | |
| Cn1cc(nc1c2c3C(=O)N(CC=C)C(=O)N(CC4CC4)c3nn2Cc5ccnc6ccc(Cl)cc56)C#N,3.92 | |
| OC(=O)C[C@H]1[C@@H](Cc2ccccc12)NC(=O)c3cc4cc(F)ccc4[nH]3,1.26 | |
| NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl,-.09 | |
| CC(=O)N1CCN(CC(O)COc2ccc(Br)cc2)CC1,1.6 | |
| Clc1ccc(cc1Cl)C2=CSC3=NCCN23,1.54 | |
| O=S(=O)(NCC(N1CCCCCC1)c2ccccc2)c3ccc(cc3)C#N,2.86 | |
| O=C1C=CN=C2C=C(C=CN12)C#Cc3ccccc3,2.9 | |
| COc1ncc2N=CC(=O)N(CCN3CCC(CC3)NCc4cc5OCCOc5cn4)c2n1,-.14 | |
| CC(C)N(C(C)C)C(=O)C(C(CNC(=O)NCc1ccccc1F)c2ccccc2)c3cccnc3,4.2 | |
| Cc1sc(CN2CCNCC2)cc1C(=O)NCC34CC5CC(CC(C5)C3)C4,2.55 | |
| Cc1cc(CCCOc2c(C)cc(cc2C)c3noc(n3)C(F)(F)F)on1,3.63 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CN=C1c2ccccc2)NC(=O)OCc3ccccc3)C(=O)C(F)(F)F,2.12 | |
| COc1cc2ncnc(Nc3cc(NC(=O)c4ccnc(c4)N5CCOCC5)ccc3C)c2cc1OCCN6CCCCC6,3.35 | |
| NC(=O)c1cncc(O[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)n1,1.1 | |
| COc1cc2c(Nc3cccc(Cl)c3Cl)c(cnc2cc1NCCN(C)C)C(=O)N,3.41 | |
| CN1C(C(=O)Nc2ncc(C)s2)C(=O)c3ccccc3S1(=O)=O,.3 | |
| CC1=CN([C@H]2CCCN(Cc3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3)C2)C(=O)NC1=O,-.55 | |
| CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)\C(=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(=O)C)[C@@H]1C)\C)cc(O)c4c3C2=O,1.19 | |
| CCN1C=C(C(=O)O)C(=O)c2cc(F)c(nc12)N3CCNCC3,-.83 | |
| COc1ccc2c(C)cc(N[C@H]3CC[C@@H](C3)NCc4cn(C)c5ccccc45)nc2c1,2.53 | |
| Cc1ccn2c(c(C)nc2c1)c3ccnc(N)n3,2.39 | |
| Cc1cc2NC(=O)C(=CC(=O)c2cc1C)O,1.99 | |
| COc1cc(N2CCCN(C)CC2)c3NC(=CC(=O)c3c1)C(=O)Nc4ccc(cc4)N5CCOCC5,2.1 | |
| CC(C)(c1cc(nc(n1)c2cccc3[nH]ccc23)N4CCOCC4)S(=O)(=O)C,2.65 | |
| CC(C)(C)OC(=O)c1ncn2c1[C@@H]3CCCN3C(=O)c4c(Br)cccc24,2.48 | |
| COc1cc2ncnc(Nc3cccc(O)c3)c2cc1OC,2.6 | |
| CC[C@H](NC(=O)c1c(CC[S+](C)[O-])c(nc2ccccc12)c3ccccc3)c4ccccc4,3.15 | |
| CCS(=O)(=O)c1ccc(c(C)c1)c2cc(Cl)ccc2OCC(=O)O,-.65 | |
| Fc1ccccc1Nc2oc(nn2)C(=O)Nc3ccc(cc3)N4CCOCC4,3.05 | |
| Nc1ccc2c(c1)C(=O)C(=O)c3cc(N)ccc23,1.72 | |
| COC(=O)N1CCOc2cc(COc3ccccc3)cnc12,2.5 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NS(=O)(=O)c3ccccc3)C(=O)C(F)(F)F,2.26 | |
| N[C@@H]1CCCN(C1)c2c(Cl)cccc2\C=C\3/SC(=O)NC3=O,1.97 | |
| CC[C@H](NC(=O)c1c([S+](C)[O-])c(nc2ccccc12)c3cccs3)c4ccccc4,3.56 | |
| CCN(C)C(=O)c1ccc(cc1)C(=C2CCN(Cc3ccc(F)cc3)CC2)c4ccccc4NC(=O)C,2.79 | |
| Nc1nccc(n1)c2cc3C(=O)NC[C@@H](CCF)c3[nH]2,.51 | |
| CCCc1nc2c(C)cc(cc2n1Cc3ccc(cc3)c4ccccc4C(=O)O)c5nc6ccccc6n5C,2.21 | |
| COc1ccc2nccc([C@@H](O)[C@@H]3C[C@H]4CCN3C[C@@H]4C=C)c2c1,2.26 | |
| FC(F)(F)c1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)N3CCN(CC3)c4ccncc4Cl,3.54 | |
| OCC(CO)CN1C(=O)C(Cc2ccccc12)NC(=O)c3cc4cc(Cl)sc4[nH]3,3.56 | |
| Cn1c(ccc1c2ccc3NC(=S)OC(C)(C)c3c2)C#N,3.4 | |
| CS(=O)(=O)c1ccc(c[n+]1[O-])C(=O)Nc2ccc(F)cc2,.84 | |
| Nc1nccc(n1)n2ccc3ccccc23,2.71 | |
| CCN(C1CCN(CCC(N2CCC(CC2)C(=O)C)c3ccccc3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,.9 | |
| CCN(CC)C(=O)c1ccc(cc1)[C@@H](N2CCN(Cc3ccc(F)cc3)CC2)c4cccc(NC(=O)C5CC5)c4,3.99 | |
| CC(C)Cc1ccc(cc1)C(C)C(=O)NS(=O)(=O)C,.78 | |
| Cc1cc(NC(=O)c2ccccc2)n[nH]1,1.75 | |
| C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc3NC(=O)C=Nc13,3.1 | |
| CC1=CN([C@H]2CCCN(C2)[C@@H](CC(C)(C)C)c3ccc(C(=O)O)c(Oc4cccc(Br)c4)c3)C(=O)NC1=O,1.12 | |
| CC(C)(NC(=O)c1sccc1Oc2ccc(F)cc2[N+](=O)[O-])C#C,3 | |
| Nc1nc2nc(cc(n2n1)C(F)(F)F)c3cccs3,2.01 | |
| Cc1c(OCC(F)(F)F)ccnc1C[S+]([O-])c2nc3ccccc3[nH]2,2.7 | |
| NC1=CC2=NNC(=O)N2c3cc(ccc13)c4cccs4,3.26 | |
| Nc1nc2ccc(cc2[nH]1)C(=O)c3ccccc3,2.29 | |
| NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)C2(F)F,-1.5 | |
| CN1C=C(C(=O)c2c(O)cc(O)cc12)c3ccc(O)cc3,2.2 | |
| CC(C)Oc1ccc2C(=O)C(=COc2c1)c3ccccc3,4.07 | |
| NC(=O)N(c1ccc(C(=O)N)c(n1)c2ccc(F)cc2F)c3c(F)cccc3F,1.6 | |
| CCCNC(=O)c1nnc2c(cccc2c1N)c3cc(C)ccc3OC,3.99 | |
| CNC(=O)c1ccc(CN2CCC(CC2)c3ccc(cc3)C(=O)Nc4ccccc4N)cc1,1.99 | |
| C[C@H](NC(=O)c1c(C)nn(C2CCSCC2)c1NS(=O)(=O)c3ccc(C)cc3)C(C)(C)C,1.29 | |
| CC[C@H]1[C@@H](Cc2cncn2C)COC1=O,-.37 | |
| NC1=CC2=NNC(=O)N2c3cc(ccc13)c4ccc[nH]4,2.3 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3c[nH]c4ncccc34)c2C(=O)N5CC[C@@H](O)C5,1.71 | |
| CCOc1cccc(\C=C\2/SC(=O)NC2=O)c1N3CCC[C@@H](N)C3,1.86 | |
| CS(=O)(=O)C1(CCOCC1)c2cc(nc(n2)c3cccc4[nH]ccc34)N5CCOCC5,2.4 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)OCc3ccncc3)C(=O)C(F)(F)F,2.41 | |
| Cc1ccc(cc1)S(=O)(=O)Nc2c(C(=O)NC3CCCCC3)c(C)nn2c4ccccc4,1.68 | |
| CN1C(=O)C(=Cc2cnc(NC3CCOCC3)nc12)Oc4ccc(F)cc4F,2.76 | |
| O=C1Oc2ccccc2C=C1c3ccccc3,3.22 | |
| COc1ccccc1C(=O)NCC23CC4CC(CC(C4)C2)C3,4.43 | |
| Cc1nc(cs1)C(=O)N2CCCC3(CCN(Cc4ccccc4)CC3)C2,.24 | |
| CS(=O)(=O)n1c2ccccc2c3cc(NC(=O)N4CCOCC4)ccc13,2.7 | |
| CCOc1ccccc1c2ccc(cc2)c3nc4ccc(F)cc4c(C(=O)O)c3C,1.18 | |
| CC(C)(C)C(=O)Nc1ccc2c(c1)C(=O)C(=O)c3ccccc23,2.83 | |
| CN1CCN(CC1)C(=O)OC2N(C(=O)c3nccnc23)c4ccc(Cl)cn4,1.1 | |
| Nc1ncnc2oc(c3cocc3)c(c4occc4)c12,3.1 | |
| OC(=O)c1ccc(Nc2ncc(Br)c(Nc3ccccc3)n2)cc1,1.65 | |
| Oc1ccc(O)c2C(=O)C=CC(=O)c12,1.91 | |
| CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccccn2,.24 | |
| C[C@@H](Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)C(=O)N(C)CCO,3.56 | |
| Oc1ccc2C(=O)C(=COc2c1)c3ccc(O)c(O)c3,1.88 | |
| Brc1ccc2oc3C(=O)NC(=Nc3c2c1)[C@@H]4CCCN4,2.19 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccc(cc3C#N)S(=O)(=O)C)cn2)C(=O)OC(C)(C)C,3.3 | |
| CN1CCN(CC1)c2cc(Nc3cc(C)[nH]n3)nc(Sc4ccc(NC(=O)C5CC5)cc4)n2,3.47 | |
| Cc1cnc(NS(=O)(=O)c2ccccc2)c(C)n1,-.03 | |
| CCCC(=O)NCc1cncc(c1)c2ccc(F)cc2OC,2.9 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)Cc3ccc(cc3)C(=O)O)C(=O)C(F)(F)F,.35 | |
| Cc1nnc2CN=C(c3ccccc3Cl)c4cc(Cl)ccc4n12,2.34 | |
| C[C@@H]1CN(CCN1C(=O)[C@@H]2CCCC[C@H]2C(=O)NC3(CC3)C#N)c4ccc5c(c4)c(C)nn5C,2.8 | |
| Cn1cc(cc1c2c3C(=O)N(CCO)C(=O)N(CC4CC4)c3nn2Cc5ccnc6ccc(Cl)cc56)C#N,3 | |
| Cc1cccc(n1)c2nc3cc(Cl)ccc3[nH]2,4.1 | |
| COC(=O)c1ccc(CC(=O)N(C)C2CCN(CCC(c3ccccc3)c4ccccc4)CC2)cc1,4 | |
| F[C@H]1CN(CCN2C(=O)C=Cc3ccc(cc23)C#N)CC[C@H]1NCc4ccc5OCC(=O)Nc5n4,.66 | |
| C[C@H](NC(=O)c1c(C)nn(C2CCN(CC(F)(F)F)CC2)c1NS(=O)(=O)c3ccc(C)cc3)C(C)(C)C,1.08 | |
| C[C@@H]1CN(CC2(CC2)C(=O)N)CCN1S(=O)(=O)c3ccc(cc3)C(C)(O)C(F)(F)F,1.03 | |
| c1ccc2[nH]ncc2c1,1.9 | |
| COCCS(=O)(=O)c1ccc(Nc2nccc(n2)c3cnc(C)n3C(C)C)cc1,2.56 | |
| Oc1ccc(CCNCCS(=O)(=O)CCCOCCc2ccccc2)c3sc(O)nc13,2.61 | |
| COc1ccc(OC(F)(F)F)cc1CN[C@H]2CCCN[C@H]2c3ccccc3,2.9 | |
| Nc1nc(cs1)c2ccc(Cl)cc2,3.31 | |
| NS(=O)(=O)c1cc(C(=O)O)c(NCc2occc2)cc1Cl,-.9 | |
| CCOC(=O)c1ccc(N)cc1,1.83 | |
| CCN(C1CCCCC1)C(=O)c2cnn(c2NS(=O)(=O)c3ccc(cc3)c4ocnc4)c5ccccc5,1.46 | |
| Oc1nc2cc(Cl)c(Cl)c(c2nc1O)[N+](=O)[O-],.21 | |
| CNCC[C@@H](Oc1cc(OC)ccc1C#N)c2ccccc2,.87 | |
| CCc1c(C)nc2sc(C(=O)N)c(N)c2c1C,2.62 | |
| OC(=O)c1ccc(OCC(=O)COc2ccc(SCCCCCc3ccccc3)cc2)cc1,3.63 | |
| COc1cc2ncc(C(=O)N)c(Nc3ccc(F)cc3F)c2cc1NCCN4CCOCC4,2.68 | |
| OCCCN1C(=O)C(Cc2ccccc12)NC(=O)c3cc4cc(Cl)sc4[nH]3,3.49 | |
| OC(=O)CC[C@H]1[C@@H](Cc2ccccc12)NC(=O)c3cc4sc(Cl)c(Cl)c4[nH]3,2.84 | |
| OCCO[C@H]1C[C@H]([C@H](O)[C@@H]1O)n2nnc3c(N[C@@H]4C[C@H]4c5ccc(F)c(F)c5)nc(SCCC(F)(F)F)nc23,4.17 | |
| Cc1cc(CNc2ncc(Cl)c(Nc3cc(C)[nH]n3)n2)on1,2.68 | |
| CCCc1cc(cc(OC)c1OC)C2=N[C@H](CO2)C(=O)NO,1.69 | |
| ON(C=O)C1(CS(=O)(=O)N2CCN(CC2)c3ccc(F)cc3)CCOCC1,.85 | |
| CC(C)[C@@H](CN1CC[C@](C)([C@@H](C)C1)c2cccc(O)c2)NC(=O)[C@H]3Cc4ccc(O)cc4CN3,2.39 | |
| OC(=O)c1cccc(c1)c2cccc(c2)C#N,.3 | |
| CC1(C)[C@@H]2CC[C@@]1(CS(=O)(=O)N3CCN(CC3)c4ccc(cn4)C(F)(F)F)C(=O)C2,3.8 | |
| CC1=CN([C@H]2CCCN(C2)[C@H](CC(C)(C)C)c3ccc(C(=O)O)c(Oc4cccc(Br)c4)c3)C(=O)NC1=O,1.09 | |
| COc1cc2ncc(C(=O)N)c(Nc3cc(C)ccc3F)c2cc1OC,3.16 | |
| COc1cc(Oc2ccnc3ccc(F)cc23)ccc1CC(=O)Nc4noc(C)c4C,4.06 | |
| Cc1cc(NC(=O)c2ccc(Cl)cc2)n(n1)c3ccccc3,3.25 | |
| OC(=O)c1ccc(cc1)n2ncc(C(=O)NC3C4CC5CC(CC3C5)C4)c2C6CCCC6,1.72 | |
| CC1=C(CCC(=O)O)C(=O)Oc2cc(O)ccc12,-.7 | |
| CC(C)(O)c1ccc(Nc2nc3ccc(cc3[nH]2)C#N)cc1,2.73 | |
| CN(C)CC(O)COc1ccc(Nc2cc(Nc3ccc(F)cc3F)ncn2)cc1,1.48 | |
| COc1cc2ncc(C(=O)N)c(Nc3ccccc3Cl)c2cc1OC,2.89 | |
| C1CNCC(C1)c2nc3ccccc3s2,1 | |
| [O-][N+](=O)c1cccc2ccc(nc12)C(Cl)(Cl)Cl,3.7 | |
| C[C@H](Nc1ncc(Cl)c(Nc2cc([nH]n2)N(C)C)n1)c3ncc(F)cn3,2.33 | |
| CN(C)C(=O)CN1C(=O)C(Cc2ccccc12)NC(=O)c3cc4cc(Cl)sc4[nH]3,3.07 | |
| CN(C)c1ccccc1S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,1.74 | |
| O=C1NC(=NC(=C1C#N)c2ccccc2)SCc3ccccc3,1.56 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)NCc3ccncc3)C(=O)C(F)(F)F,2.16 | |
| C[C@H](CO)Nc1nc(SCc2cccc(Cl)c2)nc3nc(N)sc13,3.31 | |
| CCN1CCN(Cc2ccc(cc2)c3cc4c(N[C@H](C)c5ccccc5)ncnc4[nH]3)CC1,3.97 | |
| OC(CN1CCOCC1)c2ccccc2,1 | |
| OCCN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1,3.8 | |
| CC(=O)Nc1ccc2ccn(c3cc(NCCCN4CCCC4)n5ncc(C#N)c5n3)c2c1,1.87 | |
| CN(C)c1cccc2c(cccc12)S(=O)(=O)N,1.95 | |
| Cc1[nH]c(C(=O)NC2CCN(CC2)c3nc(cs3)C(=O)O)c(Cl)c1Cl,.14 | |
| CCC[C@H](CO)Nc1nc(S[C@@H](C)c2cccc(c2)C#N)nc3NC(=O)Sc13,3.7 | |
| O[C@H](CNC(=O)C1=CNC(=O)C=C1C(F)(F)F)CN2CCC(CC2)Oc3ccc(Cl)c(Cl)c3,2.71 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NS(=O)(=O)C(F)(F)F)C(=O)C(F)(F)F,1.01 | |
| Fc1ccc(cc1)C(=O)C2CCN(CC2)C(=O)c3ccc(F)cc3,2.9 | |
| CC(C(=O)O)c1cccc(c1)C(=O)c2ccccc2,-.12 | |
| Nc1nccc(\C=C\c2ccc(Cl)cc2)n1,3.5 | |
| CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C)C=O,2.6 | |
| OC(=O)c1cccnc1Nc2cccc(c2)C(F)(F)F,1 | |
| CC1(C)COCc2sc(nc12)N3CCN(CC3)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,2.4 | |
| COc1cc2ncc(C(=O)N)c(Nc3cccc(F)c3F)c2cc1OC,2.82 | |
| OCCN1CCN(Cc2ccc3c(NC(=O)CC45CC6CC(CC(C6)C4)C5)c(Cl)ccc3n2)CC1,2.93 | |
| O=C1CCOc2cc(OCc3cccc(c3)C#N)ccc12,2.8 | |
| Cc1nc(C)c(nc1C(=O)N)c2ccc([C@@H]3CC[C@H](CC(=O)O)CC3)c(F)c2,1.2 | |
| Cn1cnc(c1Sc2ncnc3nc[nH]c23)[N+](=O)[O-],.19 | |
| CC(C)(C)OC(=O)NCCCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23,1.2 | |
| O=C(NC1(CC1)C#N)[C@@H]2CCCC[C@H]2C(=O)N3CCc4[nH]c5ncccc5c4C3,2.13 | |
| Nc1scc2C(=NN(C(=O)c12)c3ccc(F)cc3)C(=O)NC4CC4,2.8 | |
| O[C@@H](CNCCc1ccc(NC[C@H](O)c2ccccc2)cc1)c3ccc(O)c(NC=O)c3,.02 | |
| CCCC1CCCCC(=N1)N,1.1 | |
| NNC1=Nc2ccccc2NC1=O,.44 | |
| Clc1c(NCC2CCNCC2)nccc1C(=O)NCC34CC5CC(CC(C5)C3)C4,.6 | |
| COCCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC(C)C)C,3.8 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)N4CCN(CC4)C(=O)CN(C)C)n2,3.31 | |
| COCC[C@H](Oc1ncnc2c1cnn2c3ccccc3Cl)C(=O)Nc4ccc(C)cn4,3.6 | |
| OC(=O)[C@H](N1CCC(CN2CCC(CC2)Oc3ccc(Cl)c(Cl)c3)CC1)c4ccccc4,2.14 | |
| Cn1c(CN2CCN(CC2)c3cccc(Cl)c3)nc4ccccc14,3.75 | |
| CCN1C(=O)C2=C(OC(=CC2=O)O)c3ccccc13,1.13 | |
| CN([C@@H]1CCN(Cc2ccc(cc2)C(F)(F)F)C[C@@H]1F)C(=O)Cc3ccc(cc3)S(=O)(=O)C,2.7 | |
| Cc1ccc(Oc2ccc(cc2)C(=O)NCc3ccncc3)cc1,3.65 | |
| O[C@H](CNC(=O)C1=CNC(=O)c2ccccc12)CN3CCC(CC3)Oc4ccc(C#N)c(Cl)c4,2.56 | |
| NC(=N)Nc1ccc(Cl)c(Cl)c1,-.31 | |
| Cc1ccc2c(c1)c(c(C)n2CC(=O)O)c3ccnc4c(cccc34)S(=O)(=O)C,-.34 | |
| CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c2cccc3ccccc23,3.12 | |
| FC(F)(F)c1cccc(c1)S(=O)(=O)NCC(N2CCCCCC2)c3ccccc3,3.12 | |
| Oc1cccc(NC(=O)c2ccc(OCCCN3CCCC3)cc2OCc4cccc(F)c4)c1,3.15 | |
| NCCCCN(Cc1nc2ccccc2[nH]1)C3CCCc4cccnc34,.83 | |
| CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(N3CCN(CC3)c4cnccn4)c(F)c2,1.49 | |
| Oc1cccc(NC(=O)c2ccc(OCCCN3CCCC3)cc2OCc4cccc(c4)C#N)c1,2.41 | |
| CCN(CC)CCOCCOC(=O)C1(CCCC1)c2ccccc2,1.33 | |
| Fc1cccc(COc2ccc3C(=O)CCOc3c2)c1,3.4 | |
| Fc1ccc(cc1)N2CCN(CC2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NCC#N,1.92 | |
| Fc1ccc(Nc2oc(nn2)C(=O)Nc3ccc(nc3)N4CCOCC4)cc1F,2.9 | |
| Cc1c(Sc2ccc(Cl)cc2)c3cc(ccc3n1CC(=O)O)c4ccccc4,3.7 | |
| FC(F)(F)c1cc(COCC(N2CCNCC2)c3ccccc3)cc(c1)C(F)(F)F,2.9 | |
| COc1cc2ncnc(Nc3cccc(C)c3)c2cc1OC,3.5 | |
| C[C@H](NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4ccc(Cl)cc4,2.67 | |
| CN1C(=O)N(CCCCC(=O)C)C(=O)c2c1ncn2C,.22 | |
| C[C@H]1CN(Cc2cc(Cl)ccc2CC(=O)O)CCN1S(=O)(=O)Cc3ccccc3,1.12 | |
| C(Nc1nc2ccccc2[nH]1)c3ccccc3,2.76 | |
| CS(=O)(=O)N1CCOc2cc(COc3ccccc3)cnc12,2.4 | |
| OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3,3.08 | |
| COc1ccc(CN(CCN(C)C)c2ccccn2)cc1,1.39 | |
| OC(=O)c1ccc(CN2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2)cc1,1.1 | |
| OC[C@H]1CCCN1CCCOc2ccc3c(Nc4cc(CC(=O)Nc5cccc(F)c5F)[nH]n4)ncnc3c2,2.06 | |
| FC1(CCN(CC1)C(=O)COCc2ccncc2)c3ccc(Cl)cc3,3.03 | |
| COc1cnccc1COc2cnc(nc2)N3CCN(CC3)C(=O)OC(C)(C)C,3.8 | |
| NC(=O)CN1C(=O)C(Cc2ccccc12)NC(=O)c3cc4cc(Cl)sc4[nH]3,3.22 | |
| CN(C)CCNC(=O)c1c(C)[nH]c(\C=C\2/C(=O)Nc3ccc(F)cc23)c1C,1.75 | |
| Fc1ccc(Nc2oc(nn2)C(=O)Nc3ccc(nc3)N4CCOCC4)cc1,3 | |
| CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N3CCCC3)C(=O)Cc4ccccc4,.99 | |
| Cc1[nH]c(C(=O)NC2CCN(CC2)c3cc(cc(Cl)n3)C(=O)O)c(Cl)c1Cl,1.74 | |
| COc1ccc(cc1)C(=O)Nc2cc(NC(=O)c3cccc(c3)N(C)C)ccc2C,3.17 | |
| Cc1cc(C)cc(c1)c2[nH]c3ccc(cc3c2CCNCCCCc4ccncc4)C(C)(C)C(=O)N5C6CCC5CC6,4.3 | |
| C[C@H]([C@H](O)c1ccc(O)cc1)N2CCC(O)(CC2)c3ccccc3,.91 | |
| CCCSc1nc(ccc1C(=O)NC2CCCCC2)N3CCC[C@H](CC(=O)O)C3,2.18 | |
| NC(=O)Nc1sc(cc1C(=O)N[C@H]2CCCNC2)c3ccc(F)cc3,1.76 | |
| CCCSc1nc(ccc1C(=O)NC2CCCCC2)N3CCCCC3C(=O)O,1.36 | |
| Oc1ccc(cc1)C(c2ccc(O)cc2)C(Cl)(Cl)Cl,3.86 | |
| CNc1c(Br)cnc2[nH]c(nc12)c3ccc(OCCCN4CCOCC4)cc3,2.96 | |
| CSc1ccc(OCc2ccccc2)c(\C=C\c3ccc(cn3)C(=O)O)c1,2.45 | |
| CNc1cccc(CCOc2ccc(C[C@H](NC(=O)c3c(C)cc(C)cc3C)C(=O)O)cc2)n1,.52 | |
| CN1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c6cc(cn6C)S(=O)(=O)C)c3C1=O,3.18 | |
| CCCc1c(O)c(ccc1OCc2ccc(\C=C\c3nn[nH]n3)cc2)C(=O)C,3.3 | |
| C1CN=C(N1)c2ccc3ccccc3n2,.6 | |
| CCCNCc1cnc(s1)c2ccc(cc2)C(=O)Nc3ccccc3N,1.75 | |
| COC(=O)CCn1cc(c2cc(NC3CC3)n4ncc(C#N)c4n2)c5cc(NC(=O)C)ccc15,2.72 | |
| CC(C#Cc1ccccc1)N2NC(=O)C3=C(C2=O)C(=O)c4ccc(Cl)cc4N3,1.4 | |
| CC1=CC(=O)Oc2cc3NCCCc3cc12,2.7 | |
| OC(=O)COc1ccc(cc1c2cccc(c2)C#N)C(F)(F)F,.05 | |
| CNc1nc(C)c(s1)c2nc(Nc3cccc(c3)N4CCCNCC4)ncc2C#N,1.64 | |
| O[C@@H](CNCCCSCCOCCc1ccccc1)c2ccc(O)c3NC(=O)Sc23,2.3 | |
| CCNC(=O)c1cc2c(c(cnc2[nH]1)c3cncc(c3)C(=O)N)n4ccc(n4)C(F)(F)F,1.81 | |
| C\N=C(/S)\n1nc(nc1N)c2ccc(Cl)cc2,4.12 | |
| CC1=C(CCC(=O)O)C(=O)Oc2c(C)c(O)ccc12,-.3 | |
| CC(Cc1ccccc1)N(C)CC#C,2.16 | |
| C[C@H](NC(=O)c1c(C)nn(C2CCOCC2)c1NS(=O)(=O)c3ccc(C)cc3)C(C)(C)C,.5 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NS(=O)(=O)NCc3ccccc3)C(=O)C(F)(F)F,2.57 | |
| Cc1c(CC(=O)O)c2cc(F)ccc2n1S(=O)(=O)c3ccc(cc3)S(=O)(=O)C,-.44 | |
| CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1CCCN(C1)S(=O)(=O)c2ccccc2)C(C)(C)C,.9 | |
| CCCN(CCC)CCc1cccc2NC(=O)Cc12,.76 | |
| CC(NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4cccnc4,1.2 | |
| Clc1ccc(cc1C(=O)NCCc2ccccc2)N3N=CC(=O)NC3=O,.74 | |
| Cc1ccc2c(c1)c([S+]([O-])c3ccc(Cl)cc3)c(C)n2CC(=O)O,.05 | |
| CCN(CC)C(=O)c1ccc(cc1)C(=C2CCNCC2)c3ccc(Cl)c(Cl)c3,2.4 | |
| OC(=O)[C@H](Cc1cccc(c1)C#N)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,2.26 | |
| COc1ccccc1C(=O)Nc2nc3ccccc3[nH]2,2.9 | |
| CNc1ncc(s1)C(=O)c2ccccc2,2.36 | |
| COc1cc2ncnc(Nc3ccccc3)c2cc1OC,3.04 | |
| CN1CCN(CC1)c2ccc(Nc3ccnc4ccccc34)cc2,1.3 | |
| CNC[C@H](O)c1ccc(Cl)c(c1)C(=O)NCC23CC4CC(CC(C4)C2)C3,1.41 | |
| OC(CCN1CCCCC1)(C2CC3CC2C=C3)c4ccccc4,2.49 | |
| COc1ccc(CNC(=O)CSc2nc3cccnc3s2)cc1,2.5 | |
| C[C@@H](NC(=O)C)c1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,3.18 | |
| CC1=CN([C@H]2CCCN(Cc3ccc(C(=O)O)c(Oc4cccc(C)c4)c3)C2)C(=O)NC1=O,-.82 | |
| CCCc1c(O)c(O)c(C(=O)O)c2cc(Cc3ccccc3)c(C)cc12,2.6 | |
| CS(=O)(=O)Nc1cccc(NC(=O)CN2CCN([C@H](Cc3ccccc3)C2)C(=O)C[C@H](N)Cc4ccc(F)c(F)c4)c1,2.06 | |
| O=S1NC(=NO1)Cc2ccc3ccccc3c2,1.85 | |
| O=C(N1CCN(CC1)c2ccccn2)c3cccc(CC4=NNC(=O)c5ccccc45)c3,2.36 | |
| COc1cnc(nc1N(C)c2ccccc2)c3ccccn3,2.79 | |
| CS(=O)(=O)c1ccc(cc1Cl)[C@@H](C[C@H]2CCC(=O)C2)C(=O)Nc3cnccn3,1.39 | |
| Cc1nc(cs1)C(=O)N2CCOC3(CCN(Cc4ccc(Cl)cc4)CC3)C2,2.17 | |
| CN(C(=O)N1CCC(CC1)N2CCC(CC2)Oc3ccc(Cl)c(Cl)c3)S(=O)(=O)c4ccc(C)cc4,4.49 | |
| Cc1ccnc(NCc2ccccc2)c1,3.08 | |
| CN1C=CNC1=S,-.42 | |
| COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN4CCC[C@@H]4C(=O)N,3.58 | |
| CS(=O)(=O)c1cccc(Nc2nccc(Nc3c(Cl)ccc4ccoc34)n2)c1,3.7 | |
| NC(=N)Nc1ccc(cc1)C(=O)Oc2ccc(cc2)[N+](=O)[O-],.5 | |
| CCN(C1CCN(CCC(C2CCN(Cc3ccccc3)CC2)c4ccccc4)CC1)C(=O)Cc5ccc(cc5)S(=O)(=O)C,2.41 | |
| CN(C)C(=O)CC(NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4ccc(Cl)cc4,2.4 | |
| Clc1cccc(c1)S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,2.62 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4c(C)cccn34)N5CCN(CC5)C(=O)C,3.2 | |
| CS(=O)(=O)c1ccc(nc1)c2nnc(\C=C\c3oc(nn3)c4ccc(cc4)C#N)n2c5ccccc5Cl,2.66 | |
| Oc1ccc(cc1)C2=Cc3cc(O)ccc3OC2=O,2.9 | |
| CN1C(=O)CN=C(c2ccccc2F)c3cc(ccc13)[N+](=O)[O-],2.1 | |
| CCN1CCN(CC(=O)Nc2ccc(c3cccc4C(=O)C=C(Oc34)N5CCOCC5)c6sc7ccccc7c26)CC1,3.05 | |
| COc1ccc(CNCc2ccc(cc2)c3cc(C(=O)N)c(NC(=O)N)s3)cc1,2.55 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(F)cc3)n2,3.62 | |
| COc1ccc2C(=NC(=O)N(CCN3CCC(CC3)NCc4cc5OCCOc5cn4)c2c1)C,.29 | |
| COC(=O)C1C(CC2CCC1N2C)OC(=O)c3ccccc3,1.06 | |
| Cc1nc2ccc(NC(=O)CCNC(=O)N)cc2s1,.9 | |
| O[C@H](CNC(=O)c1c[nH]c2ccccc12)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,3.91 | |
| C[C@H](CO)Nc1nc(SCc2occc2)nc3NC(=O)Sc13,2.21 | |
| Clc1ccc(CNc2nc(nc3ncccc23)N4CCN(CC4)C(=O)[C@@H]5CCCN5)c(Cl)c1,2.41 | |
| O=C(CN1CCN(CC1)c2ccccc2)Nc3c(cnn3c4ccccc4)C#N,2.3 | |
| Cc1ncc([N+](=O)[O-])n1CCO,-.11 | |
| COCCN1CCN(CC(=O)Nc2ccc(C3=CC=CN4C(=O)C=C(N=C34)N5CCOCC5)c6sc7ccccc7c26)CC1,3.2 | |
| CNS(=O)(=O)c1ccc2C(=CNC(=O)c2c1)C(=O)NC[C@@H](O)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,2.77 | |
| OC1(CN2CCC1CC2)c3ccc(cc3)c4ccccc4,1.5 | |
| Oc1nnc(Cc2cccc(c2)C(=O)N3CCOCC3)c4ccccc14,1 | |
| C[C@H](Nc1ncc(Br)c(Nc2cc(C)[nH]n2)n1)c3ncc(F)cn3,2.39 | |
| CN(C1CCCCC1)C(=O)c2cnn(c2NS(=O)(=O)c3ccc(C)cc3)c4ccccc4,2.01 | |
| CSc1ncccc1C(=O)NCc2ccc(C)cc2,2.71 | |
| CNCC[C@@H](Oc1cc(ccc1C#N)C(F)(F)F)c2ccccc2,1.3 | |
| CCC(C)Nc1nc(nc(N2CCOCC2)c1N)C#N,2.8 | |
| C1Cc2ccccc2CN1c3ccncc3,1.4 | |
| CC(N)(COP(=O)(O)O)C(=O)O,2.5 | |
| Oc1ccc(Cl)cc1C(=O)Nc2ccc(F)cc2F,3.6 | |
| CN(C)C(=O)N[C@@H]1CC[C@@H](CCN2[C@@H]3CC[C@H]2C[C@H](C3)Oc4cccc(c4)C(=O)N)CC1,.12 | |
| C[C@H](NC(=O)c1c(C)nn(c1NS(=O)(=O)C2CCCCC2)c3ccccc3)C(C)(C)C,1.75 | |
| NC(=O)c1cnc(N[C@H]2CCCNC2)c3cc(sc13)c4ccc(Cl)cc4,2.78 | |
| CCN(CC)C(=O)c1ccc(cc1)C(=C2CCN(Cc3ccc(F)cc3)CC2)c4ccc(NC(=O)OC)cc4,4.01 | |
| Cc1ccccc1CCOCCCS(=O)(=O)CCNCCc2ccc(O)c3nc(O)sc23,2.84 | |
| CCN(C)C(=O)c1ccc(cc1)[C@@H](N2CCN(Cc3cccnc3)CC2)c4cccc(NC(=O)C5CCC5)c4,3.27 | |
| CC(C)CN1C(=O)N(C)C(=O)c2cn(Cc3cccc4ccccc34)cc12,4.41 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccncc3C#N)cn2)c4onc(n4)C(F)(F)F,3.1 | |
| C[C@H](O)C(=O)N1CCN(Cc2sc3c(nc(nc3c2C)c4cnc(N)nc4)N5CCOCC5)CC1,1.9 | |
| Oc1ccc(cc1)C2=Cc3ccccc3OC2=O,3 | |
| COc1cc(OC)c2nc(C)c3CCN(c4ccc(O)cc4)c3c2c1,1.5 | |
| COc1ccccc1N2CCN(CC3=C(Br)C(=O)N(N3C)c4ccccc4)CC2,2.5 | |
| CN1CCN(CC1)c2ccc3N=CN(C(=O)c3c2)c4cc(ccc4C)C(=O)Nc5ccon5,1.87 | |
| O[C@@H](CNCCSCCCNCCc1cccc(Cl)c1)c2ccc(O)c3NC(=O)Sc23,.98 | |
| CCc1[nH]c2nc(Sc3cnc4ccc[n+]([O-])c4c3)nc(N5CC[C@@H](N)C5)c2c1Cl,2 | |
| OC1(C(=O)Nc2ccccc12)c3ccccc3,1.71 | |
| NC(=O)c1ccccc1O,1.09 | |
| OCC(CO)NC(=O)CN1C(=O)C(Cc2ccccc12)NC(=O)c3cc4cc(Cl)sc4[nH]3,2.61 | |
| CC(C)Oc1cc(OCCN2CCOCC2)cc3ncnc(Nc4c(Cl)ccc5OCOc45)c13,3.68 | |
| Brc1cccc2c3CN(CCc3[nH]c12)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,3.12 | |
| NC(Cc1ccccc1)c2ccccc2,1.32 | |
| CCOC(=O)c1ccc(OC(=O)CCCCCN=C(N)N)cc1,2.41 | |
| COc1ccc2c(c1)[nH]c3c(C)nccc23,2.9 | |
| Cc1cc(ccc1O[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)C(=O)N,2.23 | |
| OCCNCCNc1ccc2c(NC(=O)CC34CC5CC(CC(C5)C3)C4)cccc2n1,1.79 | |
| Clc1cccc(NC(=O)N2CCN(C[C@@H]3CCCN(C3)C4CC4)CC2)c1,2.74 | |
| COc1ccccc1CNCCc2cccc(CCNC[C@H](O)c3ccc(O)c4NC(=O)Sc34)c2,.91 | |
| Cn1ncc(Cl)c1c2cc(sc2Cl)C(=O)N[C@H](CN)Cc3cccc(F)c3,2.99 | |
| Nc1nc(O)c2ncn(COCCO)c2n1,-1.42 | |
| CN(C)C(=O)N[C@@H]1CC[C@@H](CCN2CCN(CC2)c3cccc(Cl)c3Cl)CC1,3.6 | |
| O[C@H](CNC(=O)c1c[nH]nc1C(F)(F)F)CN2CCC(CC2)Oc3ccc(Cl)c(Cl)c3,3.34 | |
| Cc1ccc(COC(=O)N2CC[C@H](CNc3ncccn3)[C@H](F)C2)cc1,3.21 | |
| Clc1ccc2C(=O)C3=C(Nc2c1)C(=O)NN(Cc4ccncc4)C3=O,-.16 | |
| C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO,1.87 | |
| CS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4CCOc34)n2)c1,3 | |
| CS(=O)(=O)c1ccc(s1)C(=O)NC[C@@H](O)CN2CCC(CC2)Oc3ccc(Cl)c(Cl)c3,2.86 | |
| COc1cccc(c1)S(=O)(=O)c2c(C)n(CC(=O)O)c3ccc(C)cc23,-.42 | |
| Clc1ccc2C(=C3CCNCC3)c4ncccc4CCc2c1,1.48 | |
| OC(=O)CCCCn1nnc(n1)c2ccc(cc2)C(=O)N3CCC(CC3)N4CCC(CC4)Oc5ccc(Cl)c(Cl)c5,1.6 | |
| O=C(NC1(CC1)C#N)[C@@H]2CCCC[C@H]2C(=O)N3CCN(CC3)c4nc5ccncc5s4,1.6 | |
| O=C(C1CCN(CC1)c2nnc(s2)n3cccc3)N4CCN(Cc5ccc6OCOc6c5)CC4,2.5 | |
| CCN1CCOC(C1)C(=O)N2CCN(CC2)C(=O)Nc3ccc(Cl)c(Cl)c3,2.1 | |
| O=C1COC2(CCN(CC2)S(=O)(=O)c3ccc(cc3)c4ccc5cccnc5c4)CN1C6CC6,3.24 | |
| COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OC[C@@H]4CCCN(C)C4,3.05 | |
| NC(=N)NC(=O)c1nc(Cl)c(NCc2ccncc2)nc1N,-.51 | |
| Oc1ccccc1OCC(=O)NC2CCCC2,2.31 | |
| Clc1ccc(cc1C(=O)NCC23CC4CC(CC(C4)C2)C3)C5CCNCC5,1.58 | |
| CCC[C@@H](CNC(=O)c1nc(Cl)c(N)nc1N)[N+](C)(C)CCCc2ccc(OC)cc2,.4 | |
| Oc1ccc(cc1)c2oc3cc(O)ccc3n2,3.3 | |
| NC(=O)c1sc(cc1NS(=O)(=O)c2ccc(cc2)C(F)(F)F)c3ccsc3,2.39 | |
| Clc1ccc(N2CCN(CC2)C(=O)COCc3ccncc3)c(Cl)c1,3.38 | |
| CN1CCN(CC1)c2ccc3N=CN(C(=O)c3c2)c4cc(NC(=O)c5oncc5)ccc4C,1.75 | |
| CS(=O)(=O)c1ccc2OCC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,-.51 | |
| CCOC(=O)N1CCN(CC1)C(=O)[C@H](Cc2cccc(c2)C(=N)N)NS(=O)(=O)c3c(cc(cc3C(C)C)C(C)C)C(C)C,1.67 | |
| CNC1=Nc2ncccc2C(=NC1c3cccs3)c4cc[nH]c4,1.73 | |
| CC1(C)CC(=O)c2c(N)c3ccccc3nc2C1,3 | |
| C[C@H]1O[C@H]([C@H](O)[C@H]1Cl)n2cnc3c(N)nc(OCC4CC45CC5)nc23,3.68 | |
| CC(C)Oc1cc(Nc2nc(N[C@@H](C)c3ccc(F)cn3)nc(OC(CO)CO)c2Cl)n[nH]1,2.77 | |
| CCS(=O)(=O)c1ccc(c(F)c1)c2cc(Cl)ccc2OCC(=O)O,-.92 | |
| C[S+]([O-])CCN1C(=O)C(Cc2ccccc12)NC(=O)c3cc4cc(Cl)sc4[nH]3,3.17 | |
| Clc1c(ccnc1N2CCNCC2)C(=O)NCC34CC5CC(CC(C5)C3)C4,1.77 | |
| COc1ccc(cc1OC)N2CCN([C@H](C)C2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NC4(CC4)C#N,1.85 | |
| O[C@H](CNC(=O)C1=CNC(=O)c2ccccc12)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,3.42 | |
| Nc1cc(cc(c1)C(F)(F)F)C(=O)Nc2cccc(c2)c3nnn[nH]3,.2 | |
| CCN(CC)C(=O)c1ccc(cc1)C(=C2CCNCC2)c3ccccc3,1.2 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)N(C)C)n2,3.51 | |
| Fc1ccc(cc1)C(=O)N2CCC[C@@H](C2)c3onc(n3)c4ccc(F)cc4,3.73 | |
| CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)c3c(C)cc4c(C(C)C)c(O)c(O)c(C=O)c4c3O,2.75 | |
| CN(CCCOCCOCCc1ccccc1)CCc2ccc(O)c3nc(O)sc23,2.44 | |
| CCn1cc(NC(=O)Cc2ccc(Oc3ccnc4ccc(F)cc34)cc2OC)cn1,3.88 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)NCc3ccc[n+]([O-])c3)C(=O)C(F)(F)F,1.48 | |
| OC(=O)c1ccc2c(c1)nc(Nc3cccc(c3)C#C)c4ncncc24,.92 | |
| CCS(=O)(=O)c1ccc(Oc2cc3nc([nH]c3cc2CN4C(=O)CCC4=O)c5ccccn5)cc1,2 | |
| Oc1ccc(CCNCCCS(=O)(=O)NCCSCCc2ccccc2)c3sc(O)nc13,1.77 | |
| Clc1ccc(cc1C(=O)NCC23CC4CC(CC(C4)C2)C3)N5N=CC(=O)NC5=O,2.1 | |
| CCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O,1.38 | |
| Cc1ccccc1C[C@H](N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2)C(=O)O,2.54 | |
| CNC(=O)c1nc(cnc1N)c2ccc(Cl)c(c2)S(=O)(=O)Nc3cccc(F)c3F,2.8 | |
| O=C(Nc1nccs1)c2ccccc2,2.43 | |
| Fc1ccc(cc1Cl)C(=O)Nc2ccc(Cl)nc2,3.64 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c(SC3CCCCC3)c(Cc4ccccc4C(F)(F)F)sc12,4.14 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4ccccn34)N5CCNCC5,2.4 | |
| CC(C)NC(=O)NS(=O)(=O)c1cnccc1Nc2cccc(C)c2,.3 | |
| OC(=O)c1cncc(c1)c2cnc3[nH]c(cc3c2n4ccc(n4)C(F)(F)F)C(=O)NC5CC5,-.98 | |
| NC(=O)c1sc(cc1N)c2ccc(Cl)cc2,3.3 | |
| CN1C(=O)N(Cc2ccc(Br)cc2)c3ccccc13,2.81 | |
| Nc1nc2cc3CCN(Cc4cccc(F)c4)CCc3cc2s1,3.3 | |
| COc1ccc(Cl)cc1C(=O)Nc2nc3ccccc3[nH]2,4.05 | |
| CN1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c3C1=O)c6nc(cn6C)S(=O)(=O)C,2.64 | |
| CN(CCN(C)C(=O)CCOCCc1ccccc1)CCc2ccc(O)c3nc(O)sc23,2.59 | |
| COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC4CCN(CC4)S(=O)(=O)C,2.82 | |
| CC1(C)C(=O)Nc2ccccc12,2.3 | |
| CNS(=O)(=O)CCc1ccc2[nH]cc(C3CCN(C)CC3)c2c1,.48 | |
| Cc1ccc2c(c1)c(c(C)n2CC(=O)O)c3cc(C)nc4ccccc34,2.88 | |
| C1CN(CCO1)c2cc(Nc3nccc(Nc4cccc5[nH]ncc45)n3)cc(c2)N6CCOCC6,3.05 | |
| CC(C)(C)CNc1nc(nc(N2CCOCC2)c1N)C#N,3.08 | |
| O=C1Nc2ccc(cc2C1=O)S(=O)(=O)N3CCC[C@H]3CNc4ccccc4,2.4 | |
| Fc1ccc(cc1)C(=O)N2CCC(CC2)C(=O)c3ccc(Cl)cc3,3.49 | |
| OC(=O)COc1ccc(Cl)cc1CN2CCN(CC2)S(=O)(=O)c3ccccc3,.49 | |
| Nc1[nH]nc2cccc(Cl)c12,1.92 | |
| CC(C)(N)C(=O)N[C@H](COCc1ccccc1)C(=O)N2CCC3(CC2)CN(c4ccccc34)S(=O)(=O)C,1.4 | |
| C[C@H]1C[C@H](CN1C#N)NS(=O)(=O)c2cc(Br)ccc2Br,2.13 | |
| CC(C)(C)NC(=O)Nc1ccc(cc1)c2c(N)nc(N)nc2COCc3ccccc3,3.09 | |
| COc1ccc(N(C(C(=O)NC[C@@H](C)O)c2ccccc2F)C(=O)c3ccoc3Cl)c(OC)c1,2.36 | |
| C[C@H](Nc1nc(Nc2cc(C)[nH]n2)cnc1C#N)c3ccc(F)cn3,2.51 | |
| CC(=O)Nc1ccc2ccn(c3cc(NC4CC4)n5ncc(C#N)c5n3)c2c1,3.29 | |
| CCN1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c6cncn6C)c3C1=O,2.87 | |
| CCCNC[C@H](O)COc1ccccc1C(=O)CCc2ccccc2,1.69 | |
| Fc1ccc(Oc2cc(F)c(cc2F)S(=O)(=O)Nc3ncc(Cl)s3)c(c1)c4cn[nH]c4,2.7 | |
| CC1=CN([C@H]2CCCN(C2)[C@H](CC3CCOCC3)c4ccc(C(=O)O)c(Oc5cccc(Cl)c5)c4)C(=O)NC1=O,-.25 | |
| CC(=O)Nc1nc(cs1)c2cccs2,2.77 | |
| O=C1N(Cc2ccccc12)C3CCN(CCC(c4ccccc4)c5ccccc5)CC3,4.1 | |
| CCNC(=O)c1cc2c(c(cnc2[nH]1)c3cncc(c3)C(=O)O)n4nc(cc4C)C(F)(F)F,-.88 | |
| OC(=O)[C@H](Cc1ccccc1F)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,2.58 | |
| COc1cc2cc(nc(C)c2cc1OC)c3ccc(O)cc3O,3.9 | |
| Cc1cc(NC(=O)Nc2ccc(Cl)cc2)n(n1)c3ccccc3,4.15 | |
| [O-][N+](=O)c1cccc(c1)c2ccc(OCC(CCc3ccc(cc3)C(=O)N4CCCC4)N5C(=O)CCCC5=O)cc2,2.31 | |
| Oc1ccc(cc1)C2=Cc3cccc(O)c3OC2=O,2.8 | |
| OC(=O)Cc1cccc(c1)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,1.58 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(cc3)N4CCN(CC4)C(=O)CO)ncc2F,2.19 | |
| Cc1ccc(cc1)S(=O)(=O)Nc2c(cnn2c3ccccc3)C(=O)NC4CCCCC4,.8 | |
| Cn1cncc1c2c3C(=O)N(C4CC4)C(=O)N(CC5CC5)c3nn2Cc6ccnc7ccc(Cl)cc67,3.53 | |
| CC1=CN([C@H]2CCCN(C2)S(=O)(=O)c3ccc(O)c(Oc4cccc(F)c4)c3)C(=O)NC1=O,1.6 | |
| CC(C)[C@H](NC(=O)CCc1ccccc1)C(=O)N2CCCC2,2.49 | |
| COc1ccccc1C(=O)Nc2nc3ccccc3s2,3.61 | |
| COc1ccc(cc1)c2csc(n2)N(CCCN3CCOCC3)C(=O)c4occc4,3.34 | |
| O=C1CCCc2nc(ccc12)C#Cc3ccccc3,3.53 | |
| C(CCNc1cc(nc2ccccc12)c3ccccc3)CNc4cc(nc5ccccc45)c6ccccc6,3.65 | |
| CCCSc1nc(N[C@@H]2C[C@H]2c3ccccc3)c4nnn([C@@H]5C[C@H](CO)[C@@H](O)[C@H]5O)c4n1,3.99 | |
| NC(=O)c1cccc(C[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)c1,1.19 | |
| OC(CN1CCCCC1)(C(=O)c2ccccc2)c3ccccc3,3.41 | |
| CCc1ccc(CCNCCCSCCNC[C@H](O)c2ccc(O)c3NC(=O)Sc23)cc1,.86 | |
| CN1CCN(CC1)S(=O)(=O)c2ccc(c(C)c2)c3cnc(N)c(n3)C(=O)Nc4cccnc4,2.6 | |
| C[C@H](O)C(=O)N1CCN(CC1)c2ccc(Nc3nccc(n3)c4cnc(C)n4C(C)C)cc2,2.15 | |
| CN(C)c1nc(nc(n1)N(C)C)N(C)C,2.44 | |
| COC(=O)c1ccc(NC(=O)c2cc(OC)c(OC)c(OC)c2)cc1,3.2 | |
| OC1=NC(=O)CN1N=Cc2oc(cc2)c3ccc(cc3)[N+](=O)[O-],1.35 | |
| NC1(CCN(CC1)c2ncnc3[nH]ccc23)C(=O)NC(CCCN4CCCC4)c5ccc(Cl)cc5,1.3 | |
| O=C(CS(=O)(=O)c1ccccc1)c2ccccc2,1.86 | |
| Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)cc4C,1.79 | |
| COc1cccc(NC(=O)CC23CC4CC(CC(C4)C2)C3)c1C,4.21 | |
| O=C(Cc1ccccc1)Nc2nccs2,2.5 | |
| O=C(Nc1cccc2cccnc12)[C@@H]3CC[C@H](CC3)N4C(=O)[C@@H]5[C@@H]6CC[C@@H](C6)[C@@H]5C4=O,3.94 | |
| O=C(Cc1cccc2ccccc12)Nc3ccccc3,3.9 | |
| CNC1(C)C2CCC(C2)C1(C)C,-.84 | |
| N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc3cc(F)c(F)cc3F,.31 | |
| CC(C)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+](=O)[O-],3.46 | |
| C[C@H](CO)Nc1nc(SCc2csc(C)n2)nc3nc(N)sc13,1.73 | |
| COc1cc(cc(OC)c1OC)C(=O)N2CC[C@@](CCN3CCC(CC3)(C(=O)N)c4ccccc4)(C2)c5ccc(Cl)c(Cl)c5,3.23 | |
| C[C@@H](Oc1cccc2ncnc(Nc3ccc4c(cnn4Cc5cscn5)c3)c12)C(=O)N6CCOCC6,2.81 | |
| O=S(=O)(Nc1cccnc1)c2cccs2,.54 | |
| Brc1ccc(cc1)C(=O)Cn2cnc3ccccc23,3.22 | |
| CCCc1nc2c(N)nc3ccccc3c2s1,4.09 | |
| OC(=O)C1Cc2c([nH]c3ccccc23)C(N1)c4ccccc4,.78 | |
| COc1cc(CNc2nc3ccccc3[nH]2)cc(OC)c1OC,2.36 | |
| OC1=C(C(=O)Nc2cc(Cl)ccc12)c3cccc(Oc4ccccc4)c3,2.96 | |
| CCn1c2ccccc2c3cc(NC(=O)C(C)C)ccc13,4.2 | |
| COc1ccc(CNC(=O)N(CC=C)C2CCN(CCC(c3ccccc3)c4ccccc4)CC2)cc1,3.6 | |
| COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OC[C@@H]4CCCN(C)C4,2.9 | |
| CN(c1cccc(CO)c1)c2ccnc(Nc3cc(cc(c3)N4CCOCC4)N5CCOCC5)n2,2.6 | |
| C[C@H](CO)Nc1nc(SCc2csc(C)n2)nc3NC(=O)Sc13,1.73 | |
| Cn1nnc(n1)c2ccc(cn2)c3ccc(cc3F)N4C[C@H](COc5ccon5)OC4=O,1.24 | |
| CS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4OCOc34)n2)c1,2.83 | |
| NC(=O)c1cnc(N[C@H]2CCCNC2)c3cc(sc13)c4ccc(F)cc4F,1.97 | |
| CCN(C(=O)c1oc(cc1)c2ccc(Cl)cc2)c3ccc(cc3)N4CCNCC4,3.3 | |
| O=C(CCN1CCCCC1)Nc2ccc(C3=CC=CN4C(=O)C=C(N=C34)N5CCOCC5)c6sc7ccccc7c26,2.9 | |
| Cc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)c3occc3,2.17 | |
| CC(C)(C)OC(=O)N1CCN(CC1)c2ncc(OCc3ccncc3F)cn2,3.6 | |
| Cc1ccc(CN2C(=O)CCSc3ccc(Cl)cc23)cc1,3.7 | |
| CC(C)C(NC(=O)CN1C(=O)c2nc(O)nc(O)c2C=C1c3ccccc3)C(=O)C(F)(F)F,1.88 | |
| NC(=O)c1cccc(C[C@@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)c1,1.11 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3c(C)n[nH]c3C)c2C(=O)N4C[C@H](O)CO4,1.07 | |
| O=C1N(C(=Nc2c1cnn2c3ccccc3)c4occc4)c5ccccc5,3.29 | |
| Clc1ccc(OC2CCN(CC2)C3CCN(CC3)C(=O)C4=CNC(=O)c5ccccc45)cc1Cl,3.51 | |
| COc1ccc2OCC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,.87 | |
| Nc1ncnc2c1nc(Sc3nc4cccc(Cl)c4s3)n2CCO,2.37 | |
| COc1cc2ncnc(Nc3cc(NC(=O)c4cccc(c4)N5CCOCC5)ccc3C)c2cc1OC,3.6 | |
| Cc1ccccc1C(=O)N2CCN(CC2)c3ccccn3,2.18 | |
| OC(=O)[C@H](Cc1ccc(F)cc1)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)cc4Cl)CC2,2.6 | |
| COc1ccc(c(OC)c1)c2cncc(CNC3CCCC3)n2,2.14 | |
| COC1CCN(CC1)C(=O)C2CCN(CCc3c([nH]c4sc(cc34)C(C)(C)C(=O)N5C6CCC5CC6)c7cc(C)cc(C)c7)CC2,4.09 | |
| C1NCC(CC=C1)c2oc3ccccc3c2,1.94 | |
| O[C@H](CNC(=O)C1=CC(=O)Nc2ccccc12)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,3.48 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CN=C1C(C)C)NC(=O)OCc2ccccc2)C(=O)C(F)(F)F,2.63 | |
| CCN(CC)C(=O)c1ccc(cc1)[C@@H](N2CCN(CCOC)CC2)c3cccc(NC(=O)C4CC4)c3,2.35 | |
| CN(C)CCCNS(=O)(=O)c1ccc(Nc2nccc(n2)c3cnc4ccccn34)cc1,1.9 | |
| Cc1nc2ncnn2c(O)c1CCOC(=O)c3c(F)cccc3F,.16 | |
| COc1ccc(F)c(F)c1C(=O)c2cnc(NC3CCN(CC3)S(=O)(=O)C)nc2N,2.08 | |
| NC(=O)c1cccc(N[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)c1,1.01 | |
| Clc1ccc(cc1)c2cn3ccccc3n2,4 | |
| CCN1C(=O)NC(C1=O)c2ccccc2,1 | |
| CN1CCC(CC1)Oc2nccc(Nc3cc(NC(=O)c4ccnc(c4)N5CCOCC5)ccc3C)n2,1.8 | |
| Nc1nc(NCc2ccccc2)nc3c1nc(O)n3Cc4ccccc4,3.69 | |
| CCN(C1CCN(CC[C@H](C2CCN(CC2)S(=O)(=O)C)c3cccc(F)c3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,1.44 | |
| Cc1nc(C)c(nc1C(=O)N)c2ccc([C@@H]3CC[C@H](CC(=O)O)CC3)c(Cl)c2,1.7 | |
| FC(F)(F)c1cc(CO[C@H]2CCCN[C@H]2c3ccccc3)cc(c1)C(F)(F)F,3.6 | |
| CN(CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c3ccccc3)C(=O)O)cc1)c4oc5ccccc5n4,2.47 | |
| Cc1cccc(c1)C(=O)N2CCC(CC2)C(=O)c3ccc(F)cc3,3.4 | |
| Clc1ccc(cc1Cl)[C@@H]2CNCC=CC2,1.95 | |
| COC(=O)c1ccc(CN2NC(=O)C3=C(C2=O)C(=O)c4ccc(Cl)cc4N3)cc1,1.17 | |
| CCN(CC)c1ncnc2c1ncn2Cc3c(Cl)cccc3Cl,1.25 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4ccccn34)N5CC6CNCC(C5)O6,2.3 | |
| CCCS(=O)(=O)N1N=Cc2cc(Cl)ccc2B1O,-.4 | |
| CNc1ccc2ncc(c3cccc(O)c3)n2n1,2.99 | |
| CC(=O)Nc1cccc(Nc2nc(NC3CC3)n4ncc(C#N)c4n2)c1,2.1 | |
| CN1CCN(CC1)C(=O)c2cc(CC3=NNC(=O)c4ccccc34)ccc2F,1.03 | |
| C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc3nc(N)cnc13,2.89 | |
| OC(=O)c1ccc(Nc2ncc3CN=C(c4cc(Cl)ccc4c3n2)c5c(F)cccc5F)cc1,2.58 | |
| Cc1cc(CN2Cc3ccccc3C2C(=O)Nc4ccc(Cl)cc4Cl)ccc1OCC(=O)O,2.62 | |
| CCO\N=C(\C1CCN(CC1)C2(C)CCN(CC2)C(=O)c3c(C)cc[n+]([O-])c3C)/c4ccc(Br)cc4,2.14 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)N)C(=O)C(F)(F)F,1.74 | |
| CCOc1ccc(cc1)N2C(=O)c3cccnc3N=C2[C@@H](C)N(Cc4cccnc4)C(=O)Cc5ccc(OC(F)(F)F)cc5,3.7 | |
| COc1cc2nc(Nc3ccc(cc3)[C@@H](C)NC(=O)C)ncc2cc1c4ccncc4,3.11 | |
| O=C(Nc1nccs1)[C@H](CC2CCOCC2)c3ccc(cc3)S(=O)(=O)C4CC4,2.55 | |
| Cc1cccc(NS(=O)(=O)c2cccc3nonc23)c1,3 | |
| CCOc1cc2nnc(C(=O)N)c(Nc3cc(C)ccc3F)c2cc1N4CCN(C)CC4,3.02 | |
| O=S(=O)(Nc1ccccc1c2ccccc2)c3ccccc3,3.96 | |
| CC1=C(C)C(=O)C(=C(C)C1=O)C(CCCCCC(=O)O)c2ccccc2,2.48 | |
| Cc1c(Cl)ccc(OC2CCN(C[C@H](O)CNC(=O)C3=CNC(=O)C=C3C(F)(F)F)CC2)c1Cl,3.14 | |
| Cc1ccc(cc1NC(=O)c2ccc(OCc3ccccn3)cc2)c4ccc(N)nn4,2.47 | |
| CC[C@H](NC(=O)c1c([S+](C)[O-])c(nc2cc(Cl)ccc12)c3ccccc3)c4ccccc4,3.07 | |
| Fc1ccc(cc1)C(NC(=O)CC2CCN(Cc3ccn(c3)c4ccc(cc4)C(F)(F)F)CC2)C5=CNC(=O)C=C5,3.04 | |
| CCS(=O)(=O)c1ccc(c(C)c1)c2cc(ccc2OCC(=O)O)C(F)(F)F,-.45 | |
| CC(N1NC(=O)C2=C(C1=O)C(=O)c3ccc(Cl)cc3N2)c4oc5ccccc5c4,2.1 | |
| Cc1cc(CNc2nccc(Nc3cc(C)[nH]n3)n2)on1,1.86 | |
| CCCC(=O)Nc1ccc2c3ccccc3C(=O)C(=O)c2c1,2.81 | |
| CC(C)(O)c1ccccc1CC[C@@H](SCC2(CC(=O)O)CC2)c3cccc(\C=C\c4ccc5ccc(Cl)cc5n4)c3,3.45 | |
| Clc1ccc(Nc2nnc(Cc3ccncc3)c4ccccc24)cc1,3.7 | |
| Nc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2,.88 | |
| COc1ccc2nccc([C@H](O)[C@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1,2.21 | |
| Cc1nc(C)c(nc1C(=O)N)c2ccc(cc2)[C@@H]3CC[C@@H](CCC(=O)O)CC3,1.6 | |
| NC(=O)Cc1ccccc1,.3 | |
| CC(=O)O[C@H]1CC[C@]2(C=O)[C@H]3CC[C@]4(C)[C@H](CC[C@]4(O)[C@@H]3CC[C@]2(O)C1)C5=CC(=O)OC5,.64 | |
| COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN4CCC[C@H]4C(=O)N,3.58 | |
| CC(C)NNC(=O)c1ccncc1,.33 | |
| NC(=O)Nc1sc(cc1C(=O)N)c2ccccc2,2.42 | |
| Nc1ccc(N=Nc2ccccc2)c(N)n1,3.22 | |
| CCCSc1nc(NC)ccc1C(=O)N[C@@H]2C3CC4CC2C[C@@](O)(C4)C3,3.27 | |
| Oc1ccc(cc1)c2oc3c(cc(O)cc3n2)C#N,3.6 | |
| OC(=O)[C@H](Cc1ccc(cc1)C#CCCNc2ccccn2)NC(=O)c3c(Cl)cccc3Cl,.27 | |
| O=C1CCOc2nc(ccc12)C#CC3CCCCC3,3.3 | |
| Cc1ccc(cc1)N2NC(=O)c3cccnc23,2.1 | |
| COc1ccc(cc1)C(=O)N2CCCC2=O,.93 | |
| CNCc1ccc(cc1)c2[nH]c3cc(F)cc4C(=O)NCCc2c34,1.17 | |
| Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]56[C@@H](Oc1c25)c7[nH]c8[C@@H]9Oc%10c(O)ccc%11C[C@H]%12N(CC%13CC%13)CC[C@@]9(c%10%11)[C@@]%12(O)Cc8c7C[C@@]36O,1.41 | |
| Clc1cccc2[nH]ncc12,2.5 | |
| Brc1ccccc1NC(=O)Nc2ccc(C#N)c3[nH]nnc23,1.64 | |
| Nc1ccc(Cl)c(c1)c2oc3cccnc3n2,1.97 | |
| C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc3ccc(Cl)cc3NC(=O)N,1.91 | |
| CN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)c4ccncc4,2.8 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)C#N)n2,3.62 | |
| O[C@@H]1CCN(C1)c2ccc3c(NC(=O)CNc4cccc(c4)C#N)c(Cl)ccc3n2,2.39 | |
| O=C(NC1(CC1)C#N)[C@@H]2CCCC[C@H]2C(=O)N3CCN(CC3)c4nc5CCOCc5s4,1.42 | |
| Fc1ccc(CC2=NNC(=O)c3ccccc23)cc1C(=O)N4CCN(CC4)c5ccccn5,2.55 | |
| Cc1ccc(cc1)C(=O)Oc2ccc(cc2OC(=O)c3ccc(C)cc3)C(O)CNC(C)(C)C,3.57 | |
| CCCCC(CC)CNC(=O)c1ccc2c(c1)c(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c4ccccc4C)cn2C,3.66 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccc(cc3)S(=O)(=O)C)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,1.73 | |
| C[C@H](NC(=O)c1c(C)nn(C2CCS(=O)(=O)CC2)c1NS(=O)(=O)c3ccc(C)cc3)C(C)(C)C,.25 | |
| COCCOc1nc(N)c2NC(=O)N(Cc3ccccc3)c2n1,2.26 | |
| CC(C)N(c1ccnc(Nc2cc(cc(c2)N3CCOCC3)N4CCOCC4)n1)c5cc(CO)ccc5C,3.9 | |
| NC(=O)c1cc(C(=O)N)n(n1)c2cccc(c2)c3cc(ccc3C(F)(F)F)C(F)(F)F,3.4 | |
| CS(=O)(=O)Nc1cc(Nc2nccc(Nc3c(Cl)ccc4OCOc34)n2)cc(c1)C(=O)N,2.28 | |
| Oc1cc(cc(c1)C(F)(F)F)C(=O)Nc2cccc(c2)c3nnn[nH]3,.8 | |
| N#Cc1cccc(c1)c2cccc(c2)c3nn[nH]n3,.7 | |
| COc1ccc(CC(C)(C)NC[C@H](O)c2cc(O)cc3NC(=O)COc23)cc1,.79 | |
| NC1(CCC1)c2ccc(cc2)c3ncc4cnccc4c3c5ccccc5,2.2 | |
| Fc1ccccc1C(=O)Nc2c(cnn2c3ccccc3)C#N,1.7 | |
| CC1=CC(=O)Nc2ccccc12,1.9 | |
| C[C@H](Cc1cccc(CC(=O)NC23CC4CC(CC(C4)C2)C3)c1)NC[C@H](O)c5ccc(O)c(CO)c5,2.4 | |
| Oc1ccc(cc1)c2ccc(cc2)C3(O)CN4CCC3CC4,.95 | |
| CNC(=O)c1snnc1c2ccccc2,1.23 | |
| CC(C)(C)NC(=O)Nc1cccc(CN2NC(=O)C3=C(C2=O)C(=O)c4ccc(Cl)cc4N3)c1,1.77 | |
| CN1CCN(CC1)c2nc(NCCNc3ccc(cc3)[N+](=O)[O-])c4ccccc4n2,2.91 | |
| OC(=O)CSCC(=O)Nc1nc(cs1)c2ccc(F)cc2,-.2 | |
| OC(=O)[C@H](Cc1ccc(OCCNc2ccccn2)cc1)NC(=O)c3c(Cl)cccc3Cl,-.48 | |
| CC(C)(C)OC(=O)N1CCC(CC1)c2ncc(OCc3ccc(cc3)S(=O)(=O)C)cn2,2.8 | |
| CC(C)CN1C(=O)NC(=O)c2c1sc(Cc3ccccc3C(F)(F)F)c2C(=O)N4CCC4,3 | |
| Nc1ncnc2c1c(COc3cccc(Cl)c3)nn2C4CCOCC4,3.17 | |
| O=C(COCc1ccccc1)Nc2ccc3c(c2)C(=O)C(=O)c4ccccc34,3.21 | |
| OCc1ccc2ccn(c3cc(NC4CC4)n5ncc(C#N)c5n3)c2c1,3.09 | |
| CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1,-.96 | |
| NC1(CCC1)c2ccc(cc2)c3c(ccc4ccnn34)c5ccccc5,2.9 | |
| CN(C1CCN(Cc2ccc(cc2)C(F)(F)F)CC1)C(=O)Cc3ccc(cc3)n4cnnn4,3 | |
| CCC(N(CCCN)C(=O)c1ccc(C)cc1)C2=Nc3ccoc3C(=O)N2Cc4ccccc4,1.37 | |
| COc1ccc(N(C(C(=O)NC[C@@H](C)O)c2ccccc2F)C(=O)c3occc3C)c(OC)c1,2.04 | |
| CCCc1c(O)c(ccc1OCc2cccc(NC(=O)Cc3ccccc3C(=O)O)c2)C(=O)C,2.95 | |
| CC(C)OC(=O)N1CC2COCC(C1)C2Oc3ncnc(Oc4cccnc4C)c3C,3.1 | |
| C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc3nccnc13,3.15 | |
| NC(=O)c1cnc(c2ccc(cc2)C3(N)CCC3)c(c1)c4ccccc4,1.3 | |
| C[C@H](CO)Nc1nc(SCc2ccccc2)nc3NC(=O)Sc13,2.86 | |
| NCC[C@@H](Oc1cc(Cl)c(F)cc1C#N)c2ccccc2,.77 | |
| CN(c1ccnc(Nc2cc(OC3CCOCC3)cc(c2)N4CCOCC4)n1)c5cc(CO)ccc5C,3.7 | |
| CC(C)(CO)Nc1nc(SCc2cccc(F)c2F)nc3nc(N)sc13,3.37 | |
| Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccccc3,3.83 | |
| CC(C)(C)NS(=O)(=O)c1cncc(c1)c2ccc3nc(NC(=O)NCC(=O)N4CCCC4)nn3c2,1.37 | |
| O=C(Nc1ccccn1)c2ccccc2,2.2 | |
| ON1C(=O)N(CC2COc3ccccc3O2)c4ccsc4C1=O,1.44 | |
| S(c1ccccc1)c2ccc3ccccc3n2,3.92 | |
| FC(F)(F)c1cc(C(=O)Nc2cccc(c2)c3nnn[nH]3)c4nc[nH]c4c1,1.1 | |
| COC[C@H](C)Oc1cc(Oc2ccc(Cl)cc2)cc(c1)C(=O)Nc3ccc(cn3)C(=O)O,1.69 | |
| C[C@@H]1CN(CCN1C(=O)[C@@H]2CCCC[C@H]2C(=O)NC3(CC3)C#N)c4ccccc4,2.35 | |
| COc1ccc2N=CC(=O)N(CCN3CC[C@@H](NCc4cc5OCCOc5cn4)[C@H](O)C3)c2c1,.9 | |
| COCCOCCOc1ccc(cc1)c2cc(C(=O)N)c(NC(=O)N)s2,2.21 | |
| CCc1nc(N)nc(N)c1c2ccc(Cl)cc2,2.31 | |
| C[C@@H](C(=O)NCCN1CCCC1)c2ccc(OS(=O)(=O)C(F)(F)F)cc2,1.64 | |
| Nc1ccc(OCCc2ccccc2)cc1,2.71 | |
| OC(=O)CCc1ccc(OCc2cccc(Br)c2)cc1,1.67 | |
| Fc1cnc(NC(=O)C(CC2CCOCC2)c3ccc(cc3)S(=O)(=O)C4CC4)s1,3.3 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(cc3)C(=O)NC4CCN(C)CC4)ncc2F,2.13 | |
| Oc1ccc2OC(=CC(=O)c2c1)c3ccccc3,3.6 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CN=C1c2cccs2)NC(=O)OCC(F)(F)F)C(=O)C(F)(F)F,2.32 | |
| ONC(=O)C1COC(=N1)c2ccc(F)c(c2)C(F)(F)F,1.53 | |
| CCCc1c(O)c(ccc1OCCCOc2ccc3C(=O)C=C(Oc3c2CCC)C(=O)O)C(=O)C,3 | |
| NS(=O)(=O)c1ccc(Nc2nccc(n2)c3ccccc3)cc1,2.86 | |
| CC(C)[N+](C)(CCOC(=O)C1c2ccccc2Oc3ccccc13)C(C)C,.2 | |
| CCN(CC)CCNc1ncnc2c1sc3nc(N4CCOCC4)c5CCCCc5c23,3.3 | |
| CC1CC(NC(=O)C)c2ccccc2N1C(=O)c3ccccc3,2 | |
| CCN(CCNCCc1ccc(O)c2NC(=O)Sc12)C(=O)CCOCCc3ccccc3,1.92 | |
| OCC(O)CN1CCN(CC1)c2ccccc2,.4 | |
| C[C@@H](CO)Oc1cc(Oc2ccc(cc2)S(=O)(=O)C)cc(c1)C(=O)Nc3nccs3,2.63 | |
| COc1cc(OC)c(cc1NC(=O)Cc2ccnc(F)c2)S(=O)(=O)N3C(C)CCc4ccccc34,2.49 | |
| Cc1sc2ncnc(N3CCN(CC3)c4ncccn4)c2c1C,3.66 | |
| OC[C@H](O)CN1C(=O)[C@@H](Cc2ccccc12)NC(=O)c3cc4cc(Cl)sc4[nH]3,3.27 | |
| Nc1n[nH]c2nnc(c3ccccc3)c(c4ccccc4)c12,2.6 | |
| O[C@@]1(CN2CCC1CC2)C#Cc3ccc(Oc4ccc(cc4)C(=O)NCc5ccncc5)cc3,2.31 | |
| Oc1ccc(N2C(=O)c3ccc(O)cc3C2=O)c(F)c1,2.1 | |
| C[C@H]1COCCN1c2cc(nc(n2)c3cccc4[nH]ccc34)C5(CC5)S(=O)(=O)C,2.8 | |
| Cc1ccc(C[C@H](N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2)C(=O)O)cc1,3.01 | |
| COc1ccc(CC(=O)NC(N\C(=N\C#N)\Nc2ccccc2C)C(C)(C)C)cc1OC,2.48 | |
| CN1CC(c2ccc(Cl)cc2)c3ccccc3C1,3.64 | |
| OC(=O)CSc1c[nH]c2ccccc12,-1.31 | |
| OC1=C(CC2=C(O)c3ccccc3OC2=O)C(=O)Oc4ccccc14,1.22 | |
| C[C@@H](Oc1ccc(cc1C(=O)N2CCN(CC2)c3ncc(cc3F)C(F)(F)F)S(=O)(=O)C)C(F)(F)F,3.49 | |
| O=C(NCC#N)[C@@H]1CCCC[C@H]1C(=O)N2CCCCC2,.9 | |
| CNc1cccc(CCOc2ccc(C[C@H](NC(=O)c3ccccc3Cl)C(=O)O)cc2)n1,-.31 | |
| Cc1nnc2CN=C(c3ccccc3)c4cc(Cl)ccc4n12,1.98 | |
| COCCC(=O)N[C@@H](C)c1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,3.05 | |
| COc1ccc(cc1OC2CCCC2)[C@@]3(CC[C@H](CC3)C(=O)O)C#N,.76 | |
| CCOc1ccccc1c2ccc(cc2)c3nc4ccc(F)cc4c(C(=O)NCCOCCN)c3C,2.46 | |
| Cc1ccc(cc1c2cc(ccc2OCC(=O)O)C(F)(F)F)C#N,.15 | |
| CS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1,2.91 | |
| COCCNS(=O)(=O)c1ccc(cc1)c2cnc(N)c(n2)C(=O)Nc3cccnc3,2.26 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2CCCN(C2)C(=O)c3ccccc3,.87 | |
| Oc1c(NC(=O)Nc2cccc(F)c2Cl)ccc(Cl)c1S(=O)(=O)N3CCNCC3,2.6 | |
| CN1CCC(=CC1)c2cccc(O)c2,.53 | |
| OC(=O)COc1ccc(C(=O)c2cccs2)c(Cl)c1Cl,-.84 | |
| COCC1=C(N2[C@H](SC1)[C@H](NC(=O)\C(=N/OC)\c3csc(N)n3)C2=O)C(=O)OC(C)OC(=O)OC(C)C,1.7 | |
| OCCN(CCO)c1nc(N2CCCCC2)c3nc(nc(N4CCCCC4)c3n1)N(CCO)CCO,3.97 | |
| CS(=O)(=O)c1ccc(cc1)C(CCNC(=O)c2ccc(cc2)C#N)c3ccc(F)cc3,2.9 | |
| Cc1cccc2c(CCNCc3cccc(CCNC[C@H](O)c4ccc(O)c5NC(=O)Sc45)c3)c[nH]c12,1.13 | |
| CC1=CN([C@H]2CCCN(C2)S(=O)(=O)c3ccc(CO)c(Oc4cccc(Cl)c4)c3)C(=O)NC1=O,2.69 | |
| Nc1ncnc2c1ncn2[C@@H]3O[C@H](CSCCCNC(=O)Nc4ccccc4)[C@@H](O)[C@H]3O,1.9 | |
| CCN(CC)CCOC(=O)C1(CCCCC1)C2CCCCC2,3.72 | |
| CC12NC(Cc3ccccc13)c4ccccc24,1.7 | |
| COc1ccc(cc1)N2CCN(CC2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NC4(CC4)C#N,1.74 | |
| C[C@@H]1CN([C@@H](CO1)c2ccccc2)c3ccc4OCC(=O)Nc4n3,2.75 | |
| CC(C)c1ccc2[nH]c3CCN(Cc3c2c1)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,4.1 | |
| Cc1nc2ccccn2c1c3ccnc(Nc4cccc(Cl)c4)n3,2.7 | |
| OC(=O)COc1ccc(Cl)cc1CN2CCN(CC2)S(=O)(=O)c3ccc(F)cc3,.99 | |
| Oc1ccc(CCNCCCS(=O)(=O)NCCOCCSc2ccccc2)c3sc(O)nc13,1.84 | |
| CCc1nc2ccc(cn2c1N(C)Cc3cccs3)C(=O)NCc4ccc5OCOc5c4,4.1 | |
| COCc1ccoc1C(=O)N(C(C(=O)NC[C@@H](C)O)c2ccccc2F)c3ccc(OC)cc3OC,1.98 | |
| CN(C)c1cccc(c1)C(=O)Nc2ccc(C)c(NC(=O)c3ccc(O)cc3)c2,2.65 | |
| COc1cc(F)ccc1c2cncc(CNC3CCC3)n2,2.23 | |
| Cc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1,3.7 | |
| COc1cc2CC(CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC,2.41 | |
| CCN(CC)C(=O)c1ccc2[nH]c(c(CCNCCCCc3ccncc3)c2c1)c4cc(C)cc(C)c4,3.3 | |
| Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc4cccc(c4)S(=O)(=O)NC(C)(C)C,2.11 | |
| Nc1ncc(cc1c2oc3ccccc3n2)c4cnn(c4)C5CCNCC5,1.85 | |
| Nc1cc(nc2c(cnn12)C#N)c3ccc(F)cc3,2.23 | |
| NS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1,2.6 | |
| C[C@@H](N(c1cc(F)ccc1F)S(=O)(=O)c2ccc(Cl)cc2)c3ccc(F)cc3CCCC(=O)O,3.1 | |
| Cc1nc(CS(=O)(=O)c2ccccc2)cc(n1)N3CCOCC3,1.07 | |
| COc1ccc(cc1)[C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(=O)C,1.99 | |
| Cc1ccc(cc1)S(=O)(=O)N2N=Cc3ccccc3B2O,.05 | |
| S=C(NC1CCCCC1)N2CCC(CC2)c3cnc[nH]3,2.3 | |
| Nc1cc(nc2ccccc12)c3ccccc3,2.2 | |
| CN(C1CCN(Cc2ccc(nc2)C(F)(F)F)CC1)C(=O)Cc3ccc(cc3)n4cnnn4,1.8 | |
| COc1ccc(cc1)c2cc3c(N[C@H]4CCCNC4)ncc(C(=O)N)c3s2,1.82 | |
| C[N+]1(C)[C@@H]2C[C@H](C[C@H]1[C@@H]3O[C@H]23)OC(=O)C(O)(c4cccs4)c5cccs5,-.25 | |
| NC(=N)c1cc2c(cccc2s1)c3ccccc3,1.27 | |
| Clc1ccc(CN2C(=O)C(=O)c3ccccc23)cc1,3.1 | |
| COc1ccccc1O[C@H]([C@@H]2CNCCO2)c3ccccc3,.9 | |
| CCCNC(=O)c1nnc2c(cccc2c1N)c3ncccn3,1.86 | |
| O[C@@H](CNCCc1ccc(CNCCc2c(Cl)cccc2Cl)cc1)c3ccc(O)c4NC(=O)Sc34,2.3 | |
| CC1CN(CCN1Cc2cc(Cl)ccc2OCC(=O)O)S(=O)(=O)c3ccccc3,.69 | |
| Clc1ccc(cc1)C2CCN(CC2)C(=O)COCc3ccncc3,2.74 | |
| CC(O)(C(=O)Nc1ccc(cc1)S(=O)(=O)c2ccncc2)C(F)(F)F,2.15 | |
| CCN(CC)CCN1C(=O)[C@@](O)(c2ccccc2Cl)c3c1cc(cc3C(F)(F)F)C(=O)N,2.4 | |
| OCCNS(=O)(=O)c1ccc2C(=CNC(=O)c2c1)C(=O)NC[C@@H](O)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,2.06 | |
| CN(c1ccnc(Nc2cc(nc(c2)N3CCOCC3)N4CCOCC4)n1)c5cc(CO)ccc5C,3.44 | |
| Clc1ccc(cc1)C(=O)N[C@H]2CN3CCC2CC3,.6 | |
| CC1=C(OCc2ccc(F)cc2)C(=O)C=CO1,1.91 | |
| Clc1ccc(cc1)C(=O)Cc2ccccn2,2.96 | |
| COc1nc(Br)cnc1NS(=O)(=O)c2cccc3c(cccc23)N(C)C,1.9 | |
| NC(=O)c1sc2nccc(Nc3ccccc3)c2c1N,2.91 | |
| COc1ccccc1OCC(O)COC(=O)N,.36 | |
| Clc1ccc2C(=O)NC(=Nc2c1)c3ccccc3,3.31 | |
| Oc1cc(O)c2C(=O)c3ccccc3Oc2c1,3.39 | |
| CCC(Oc1ccc(cc1c2ccc(cc2C)S(=O)(=O)CC)C(F)(F)F)C(=O)O,.31 | |
| COC(=O)N1CCN([C@@H](CN2CCCC2)C1)C(=O)Cc3ccc(Cl)c(Cl)c3,1.97 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)S(=O)(=O)CCCN(C)C)n2,1.32 | |
| CC1(C)CCC(CC1)NC(=O)[C@@H](N)CCC(=O)O,-.27 | |
| NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C3CC4CC3C=C4)cc1Cl,2.12 | |
| Oc1ccc(Br)c2ccccc12,4.3 | |
| CNC(=O)c1ccc(cc1F)N2C(=S)N(C(=O)C23CCC3)c4ccc(C#N)c(c4)C(F)(F)F,3.3 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2CCCN(CCc3cccc(F)c3)C2,2.64 | |
| CCCC1=CC(=CC(=O)N1Cc2ccc(cc2)c3ccccc3c4nn[nH]n4)OCc5ccccc5,2.4 | |
| O=C(NC1(CC1)C#N)[C@@H]2CCCC[C@H]2C(=O)N3CCN(CC3)c4nccs4,1.3 | |
| CCSc1ccc(cc1)c2cc(ccc2OCC(=O)O)C(F)(F)F,1.54 | |
| COc1ccc(CN2C(=O)CCC2(C)C(=O)NC3CCCCC3)c(OC)c1,2.38 | |
| O=C1C(=O)c2cc(ccc2c3ccccc13)c4ccsc4,3.1 | |
| CN(C)CC(O)COc1ccc(Nc2nccc(Nc3cc(Cl)ccc3Cl)n2)cc1,2.9 | |
| CN(C)CCCNC(=O)c1nc(Cl)c(N)nc1N,-1 | |
| Cc1ccc(cc1)\C(=C/CN2CCCC2)\c3ccccn3,1.88 | |
| COc1cc(ccc1Nc2ncc(C#N)c(n2)c3cnc4ccccn34)N5CCN(CC5)C(=O)C,2.8 | |
| CCCCC(CC)CNC(=O)c1cc(ccc1Cl)N2N=CC(=O)NC2=O,2.41 | |
| CN(C)C(=O)N[C@@H]1CC[C@@H](CCN2CCN(CC2)c3ccc(Cl)c(Cl)c3)CC1,3.15 | |
| Oc1c2ncc3ccccc3c2nn1c4ccccc4,.8 | |
| Cc1c(Sc2ccc(Cl)cc2)c3c(cccc3n1CC(=O)O)c4cnccn4,.03 | |
| C(Oc1ccccc1)C2CNCCO2,.2 | |
| COc1ncc(C)cc1c2cccc3c(N)c(nnc23)C(=O)NC4CC4,3.4 | |
| OC(=O)COc1ccc(Cl)cc1CN2CCCN(CC2)S(=O)(=O)c3ccccc3,1.01 | |
| O[C@@H](CNCCc1cccc(CNCCc2c(Cl)cccc2Cl)c1)c3ccc(O)c4NC(=O)Sc34,3.15 | |
| CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C\2/C(=O)Nc3ccc(F)cc23)c1C,2.26 | |
| Clc1ccc(OC2CCN(CC2)C3CCN(CC3)C(=O)NS(=O)(=O)c4ccccc4)cc1Cl,1.5 | |
| Fc1ccc(cc1)[C@@H]2CCNC[C@H]2COc3ccc4OCOc4c3,1.78 | |
| O=C(N1CCOCC1)N2CCn3cc(C4=C(C(=O)NC4=O)c5cnc6ccccn56)c7cccc(C2)c37,1.79 | |
| CN1CCN(CCCOc2ccc(cc2)c3onc(c3)c4ccc(F)cc4)CC1,3.81 | |
| N#Cc1nc(nc(n1)N2CCOCC2)N3CCOCC3,1.51 | |
| CNc1ccc(cc1)c2nc3ccc(O)cc3s2,3.5 | |
| CN1CCN(CC1)C(=O)c2cc3cc(F)ccc3[nH]2,1.97 | |
| Clc1ccc(cc1)C(=O)\C=C\Sc2nc[nH]n2,3.1 | |
| O=C1C2CCC(N2)C(=O)N1Cc3ccccc3,2.21 | |
| CN1N=Nc2c(ncn2C1=O)C(=O)N,-1.08 | |
| Fc1cc2[nH]cnc2cc1Cl,2.35 | |
| CC(=O)Nc1ccc(CNc2[nH]nc3cccc(Oc4ccc(F)cc4)c23)cc1,4.28 | |
| N[C@H](CNC(=O)c1cc2c(cccc2[nH]1)c3ccccc3Cc4ccccc4)C(=O)O,3.25 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)NCc4ccc(cc4)S(=O)(=O)C,2.86 | |
| CCN(CC)C(=O)Cc1csc(NS(=O)(=O)c2cccc(Cl)c2C)n1,1.67 | |
| CCCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4F)[nH]n3)ncnc2c1,2.19 | |
| CCCc1c(cnn1c2ccccc2)C(=O)Nc3cc(C)on3,3.7 | |
| O=C(CC1CCCCCC1)Nc2cccc3C(=O)N(C=Cc23)[C@H]4CCNC4,1.15 | |
| OC(=O)c1cc(ccc1O)N=Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3,-.58 | |
| OC(=O)c1c(Sc2ccccc2)c3cc(Cl)ccc3n1Cc4ccc(Cl)cc4,2.96 | |
| Cc1ccc(cc1NC(=O)c2ccc(OCc3ccccn3)cc2)c4ncc(CN5CCOCC5)s4,3.1 | |
| Cc1oc(cc1C(=O)Nc2cccc(c2)C(=O)O)c3ccccc3,1.63 | |
| CCN(CC)C(=O)c1ccc(cc1)C(=C2CCN(Cc3ccc(F)cc3)CC2)c4cccc5cccnc45,3.86 | |
| CCN(CC)S(=O)(=O)c1ccc(NC(=O)C(C)(O)C(F)(F)F)cc1,2.63 | |
| COc1ccc2NC(=O)C(NC(=O)c3ccccc3OC)N=C(c4ccccc4)c2c1,3.8 | |
| CC(CO)(CO)Nc1nc(SCc2cccc(F)c2F)nc3nc(N)sc13,2.87 | |
| C[C@@H](Oc1ccc(SCCCCCc2ccccc2)cc1)C(=O)c3nc(C)c(CCCC(=O)O)s3,3.58 | |
| COC(=O)COc1ccc(OCCNCC(O)COc2ccccc2)cc1,1.54 | |
| COc1ccnc(CSc2nc3ccccc3[nH]2)c1,2.89 | |
| Oc1cccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)c1,2.3 | |
| Oc1c2C(=O)N(NC(=O)c2nc3cc(Cl)ccc13)C(C4CC4)c5ccccn5,1 | |
| CN(C1CCN(Cc2ccc(cc2)C(F)(F)F)CC1)C(=O)Cc3ccc(cc3F)S(=O)(=O)C,2.7 | |
| Fc1ncccc1OC[C@@H]2CCN2,-1.2 | |
| Oc1cccc(NC(=O)c2ccc(OCCCN3CCCC3)cc2OCc4ccccc4C#N)c1,2.34 | |
| COc1ccc(cc1)c2nc3c(NCCCNC(=O)C)c(Br)cnc3[nH]2,3.28 | |
| COc1ccc(N(C(C(=O)NC2CCCC2)c3ccccc3F)C(=O)c4ccccc4)c(OC)c1,3.86 | |
| Cc1ccnc(NCc2ccc(Cl)cc2)c1,3.6 | |
| CCN(c1ccnc(Nc2cc(cc(c2)N3CCOCC3)N4CCOCC4)n1)c5cc(CO)ccc5C,3.8 | |
| CCN(CCO)CCCOc1cc2ncnc(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)c2cc1OC,2.12 | |
| CCCc1c(O)c(ccc1OCc2ccc(cc2OC)c3nn[nH]n3)C(=O)C,2.8 | |
| Nc1nc(N)c(c(COCc2ccccc2)n1)c3ccc(NC(=O)C4CC4)cc3,2.46 | |
| O=C(N1CCOCC1)c2ccc(cc2)C(=C3CCN(Cc4cscn4)CC3)c5cccc6cccnc56,2.12 | |
| Clc1ccc(OC2CCN(CC2)C3CCN(CC3)C(=O)NS(=O)(=O)Cc4ccccc4)cc1Cl,2.13 | |
| C[C@@H](Oc1nc(Nc2cc(C)[nH]n2)c(C)nc1C#N)c3ccc(F)cn3,2.72 | |
| O[C@]1(CN2CCC1CC2)C#Cc3ccc(Oc4ccc(cc4)C(=O)NCc5ccncc5)cc3,2.42 | |
| COc1cc(Nc2cc(Oc3cc(C)c(C)nc3c4ccccn4)ccn2)cc(OC)c1OC,3.22 | |
| CSc1nc(C(=O)N)c(N)s1,1.21 | |
| COc1ccccc1CN(C(=O)C)c2cnccc2Oc3ccccc3,3 | |
| COc1cccc(CNc2nc(NC(C)C)nc3ccsc23)c1OC,3.7 | |
| OCCN1C=Cc2c(NC(=O)Cc3ccc(Cl)c(c3)C(F)(F)F)cccc2C1=O,3.36 | |
| C[C@H](NC(=O)c1c(C)nn(C2CCOCC2)c1NS(=O)(=O)c3ccc(cc3)C4CC4)C(C)(C)C,1.23 | |
| CCC(NC(=O)c1ccc(C)cc1)C2=Nc3ccsc3C(=O)N2Cc4ccccc4,4.14 | |
| OC[C@@H](O)CN1C(=O)[C@H](Cc2ccccc12)NC(=O)c3cc4cc(Cl)sc4[nH]3,3.27 | |
| COc1ccc2N=CC(=O)N(CCN3CC[C@@H](NCc4ccc5OCC(=O)Nc5n4)[C@@H](O)C3)c2c1,.37 | |
| c1ccc2ncccc2c1,2.09 | |
| C[C@H](NC1=NC(=O)[C@@](C)(S1)C(F)(F)F)c2ccccc2F,3.1 | |
| C[C@@H](N)COc1c(C)cccc1C,.6 | |
| CC1N=C(N)N=C(N)N1c2ccc(Cl)cc2,-.8 | |
| COc1cc2ncnc(Nc3cc(Cl)ccc3F)c2cc1OCCCN4CCOCC4,3.4 | |
| Cc1ccccc1N2C(=Nc3cccc(C)c3C2=O)Cn4cnc5c(N)ncnc45,2.6 | |
| COc1ccc2nc3ccccc3c(N)c2c1,1 | |
| Cc1ccc2c(c1)c(c(C)n2CC(=O)O)c3ccnc4c(cccc34)C(F)(F)F,1.27 | |
| CC[C@H](NC(=O)c1c([S+](C)[O-])c(nc2ccccc12)c3ccsc3)c4ccccc4,2.66 | |
| Cc1oncc1C(=O)Nc2ccc(cc2)C(F)(F)F,3.9 | |
| C[C@@H]1CN(C[C@H](C)O1)c2nc(N3CCOCC3)c4ccc(Nc5ccccc5)nc4n2,4.12 | |
| OCC(=O)N1CCC(CC1)c2n[nH]c(c3ccc(Cl)cc3)c2c4ccncn4,1.85 | |
| COc1ccc(cc1OC)C(=O)Nc2cc(NC(=O)c3cccc(c3)N(C)C)ccc2C,3.12 | |
| CNCc1cccc(c1)c2ccc3c(nc(nc3n2)N4C[C@@H](C)O[C@@H](C)C4)N5CCOCC5,1.26 | |
| COc1ccc(cc1)c2nc3c(OCC4CCNCC4)c(Br)cnc3[nH]2,1.55 | |
| COc1ccc(cc1)c2nc3c(NCCCNC(=O)c4ccccc4)c(Br)cnc3[nH]2,.25 | |
| C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)nc(OCC4CC(F)(F)C4(F)F)nc23,1.42 | |
| O=C(NC1CC1)Nc2c[nH]nc2c3nc4cc(CN5CCOCC5)ccc4[nH]3,2.3 | |
| Cc1ccc(cc1NC(=O)c2ccc(OCc3ccccn3)cc2)c4ncc[nH]4,3.01 | |
| Nc1cc(ncn1)c2ccccc2,1.91 | |
| Cc1onc(NS(=O)(=O)c2ccc(N)cc2)c1,-.56 | |
| Clc1ccc2C(=O)C3=C(Nc2c1)C(=O)NN(Cc4cc5ccccc5s4)C3=O,2 | |
| OC(=O)[C@H](Cc1ccc(OCCCNc2ccccn2)cc1)NC(=O)c3c(Cl)cccc3Cl,-.22 | |
| CC(C)(C)OC(=O)N1CCN(CC1)c2cnc(OCc3ccc(cc3)S(=O)(=O)C)cn2,3.4 | |
| CC(C)c1cc(C(=O)N2Cc3ccc(CN4CCN(C)CC4)cc3C2)c(O)cc1O,2.5 | |
| COC1(CCOCC1)c2cc(F)cc(OCc3ccc4N(C)C(=O)C=Cc4c3)c2,3.52 | |
| Oc1ccc(CCNCCS(=O)(=O)CCCOCCNc2ccccc2)c3sc(O)nc13,1.98 | |
| C[C@H](Nc1ncc(F)c(Nc2cc(C)[nH]n2)n1)c3ncc(F)cn3,1.79 | |
| COc1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cc1OCCN(C)CCO)C(=O)N,3.2 | |
| C(Nc1ncnc2ccccc12)c3ccccc3,3.21 | |
| CC(N1C(=O)c2ccccc2C1=O)C(=O)N3CCc4ccccc4C3,2.47 | |
| Nc1ccc(cc1)C2(CCCCC2)c3ccc(N)cc3,3.2 | |
| CS(=O)(=O)c1ccc(cc1)[C@@H](CC2CCCC2)C(=O)Nc3nccs3,3.86 | |
| CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C\2/C(=O)Nc3ccc(Cl)cc23)c1C,2.75 | |
| CC(C)(C)OC(=O)N1CCC(CC1)OCc2onc(n2)c3ccncc3,3 | |
| C[C@@](O)(C(=O)Nc1ccc(cc1Cl)S(=O)(=O)C)C(F)(F)F,2.08 | |
| Clc1ccc2nsnc2c1NC3=NCCN3,.71 | |
| CCS(=O)(=O)Nc1cccc2c1c(Oc3ccc(Cl)cc3)c(C)n2CC(=O)O,-.29 | |
| CNc1cccc(CCOc2ccc(C[C@H](NC(=O)c3ccc(F)cc3Cl)C(=O)O)cc2)n1,-.04 | |
| CCCc1c(O)c(ccc1OCc2ccc(cc2)c3nn[nH]n3)C(=O)C,3.1 | |
| COc1cc(OC)c(cc1NC(=O)C)S(=O)(=O)N(C)c2ccccc2,1.1 | |
| OCCCN(Cc1ccc(F)cc1)C(=O)CC2CCN(Cc3ccn(c3)c4ccc(cc4)C(F)(F)F)CC2,3.04 | |
| CN(C1CCN(Cc2ccc(cc2)c3noc(C)n3)CC1)C(=O)Cc4ccc(cc4)n5cnnn5,2.1 | |
| CN1CCN(Cc2ccc(cc2)C(=O)Nc3ccc(C)c(Nc4nccc(n4)c5cccnc5)c3)CC1,2.5 | |
| CCCCNc1nc(SCCC)nc2c1nnn2[C@@H]3C[C@H](CO)[C@@H](O)[C@H]3O,3.07 | |
| CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1CCCN(CCc2ccccn2)C1)C(C)(C)C,-.55 | |
| OC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F,2.01 | |
| CC1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1S(=O)(=O)c3ccccc3,.31 | |
| O[C@H](CNC(=O)C1=CNC(=O)c2ccc(F)cc12)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,3.93 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3ccccc3C(F)(F)F)c2S(=O)(=O)N4CC[C@@H](O)C4,3.32 | |
| Cc1ccccc1S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,1.71 | |
| COc1cccc(n1)N(C)c2ccnc(Nc3cc(cc(c3)N4CCOCC4)N5CCOCC5)n2,3.37 | |
| CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2[C@H]3CCC[C@H]3C[C@H]2C(=O)O,-.41 | |
| OC(=O)c1cn(Cc2ccccc2)c3ccccc13,1.19 | |
| CN(C)c1cccc(c1)C(=O)Nc2ccc(C)c(NC(=O)c3ccc(OCc4ccccn4)cc3)c2,2.83 | |
| CC(C)(C)Cn1c(CN2C(=O)CC3(CCNCC3)C2=O)cc4cnc(nc14)C#N,.75 | |
| CCN1CCN(Cc2cnc(c(Cl)c2)c3ccc(cc3)C(=O)Nc4ccccc4N)CC1,1.81 | |
| CNC(=O)Nc1cc(sc1C(=O)N)c2ccccc2,2.71 | |
| CCCSc1ncccc1C(=O)NC2CCC(F)(F)CC2,2.85 | |
| Cc1ccc(cc1)C(=O)C2CCN(CC2)C(=O)c3ccc(C)cc3,3.43 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4cc(CO)ccn34)N5CCN(CC5)C(=O)C,3.1 | |
| Cc1ncc(c2ccnc(Nc3ccc(cc3)S(=O)(=O)N)n2)n1C,1.6 | |
| CNc1nc(C)c(s1)c2nc(Nc3cccc(c3)N4CCNCC4)ncc2C#N,1.9 | |
| Clc1ccc(NC(=O)N2CCN(C[C@H]3CN(CCO3)C4CC4)CC2)cc1Cl,3.32 | |
| CCC(N(CCCN)C(=O)c1ccccc1)C2=Nc3ccsc3C(=O)N2Cc4ccccc4,1.38 | |
| NC1=NC(Nc2cccc(F)c12)c3cccs3,.91 | |
| CN1C(=O)CN=C(c2ccccc2)c3cc(Cl)ccc13,2.69 | |
| Cn1cncc1c2c3C(=O)N(CC=C)C(=O)N(CC4CC4)c3nn2Cc5ccnc6ccc(Cl)cc56,3.62 | |
| CC(C)(N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc3c[nH]c4ccccc34)NC=O,1 | |
| c1ccc(cc1)c2c[nH]c(n2)c3ccccc3,3.8 | |
| CCC1(NC(=O)N(C)C1=O)c2ccccc2,1.59 | |
| O[C@H]1CN(CCN2C(=O)C=Cc3ccc(cc23)C#N)CC[C@H]1NCc4cc5OCCOc5cn4,.45 | |
| Cc1c(CCC(=O)O)c[nH]c1\C=C\2/C(=O)Nc3ccccc23,1.05 | |
| COCCOc1cc2ncc(C(=O)N)c(Nc3ccc(C)cc3F)c2cc1N4CCN(C)CC4,2.24 | |
| COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC4CCN(C)CC4,2.72 | |
| Clc1cccc(Cl)c1\C(=C\n2cncn2)\OC3CCCCCC3,4.1 | |
| Brc1oc(cc1)c2nc3cc(NS(=O)(=O)c4ccccc4)ccc3[nH]2,4.38 | |
| Nc1c2C(=O)N(Cc2nc3c(cccc13)c4ncccn4)C5CCC5,1.85 | |
| COc1ccc(cc1)c2c(C)[nH]nc2c3ccc(O)cc3O,3.37 | |
| CNCC[C@H](Oc1cccc2ccccc12)c3cccs3,2.09 | |
| CC(N1Cc2ccccc2C1=O)c3ccccc3,3 | |
| COc1ccc(N(C(C)C(=O)NC2CCCC2)C(=O)c3ccccc3)c(OC)c1,3.02 | |
| NC1=NC(=CC(=O)N1)CCc2ccccc2,1.4 | |
| COCCOc1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,3.1 | |
| C[C@H](Nc1nc(Nc2cc(C)[nH]n2)c(F)cc1C#N)c3ccc(F)cn3,3.11 | |
| OC(=O)CN1C(=O)C(Cc2ccccc12)NC(=O)c3cc4sc(Cl)c(Cl)c4[nH]3,.67 | |
| CC(C)n1c2ccccc2c3c(C)c(NC(=O)N4CCOCC4)ccc13,3.5 | |
| Fc1ccccc1c2ccc3c(c2)C(=O)C(=O)c4ccccc34,2.92 | |
| Cc1cc(C)cc(CCOCCS(=O)(=O)NCCNCCc2ccc(O)c3nc(O)sc23)c1,2.45 | |
| Cc1ccc2c(N)c(C#N)sc2n1,2.23 | |
| O=S(=O)(Nc1ccc(cc1)S(=O)(=O)Nc2nccs2)c3ccc4OCCOc4c3,1.97 | |
| COc1ccc(cc1)C(CNC(=O)Nc2ccccc2)N3CCN(C)CC3,1.5 | |
| COc1ccc(Nc2cc(Oc3cc(C)c(C)nc3c4ccccn4)ccn2)cc1,3.51 | |
| COc1ccc(NC(=O)c2ccc(c(C)c2)c3ccncc3)cc1N4CCN(C)CC4,2.56 | |
| CCCSc1ncccc1C(=O)N(C)C2CCCCC2,3.36 | |
| CCOC(=O)C1=Cc2ccc(O)cc2OC1=O,1.2 | |
| COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OC,3.67 | |
| OC(=O)COc1ccc(cc1c2ccccc2)[N+](=O)[O-],-.69 | |
| CCCSc1c(cnn1c2cccc(c2)C(=O)O)C(=O)NC3CCCCC3,.7 | |
| Nc1ncnc(Nc2ccccc2)n1,1.4 | |
| NC(=O)Nc1sc(cc1C(=O)N[C@H]2CCCNC2)c3ccsc3,1.06 | |
| CCN(CC)CCOc1ccc(cc1)\C(=C(\Cl)/c2ccccc2)\c3ccccc3,4.09 | |
| COc1cc(O)c2C(=O)O[C@@H](C)C\C=C/C(=O)[C@@H](O)[C@@H](O)C\C=C\c2c1,1.64 | |
| CCN1N(C2CCCC2)c3nc(Nc4ccc(cc4OC)C(=O)NC5CCN(C)CC5)ncc3N(C)C1=O,2.75 | |
| COc1ccccc1Oc2ccc(cc2)N(Cc3cccnc3)S(=O)(=O)CC(F)(F)F,1.5 | |
| O=C1C=C(C=CN1c2ccc3c(cnn3CCN4CCCC4)c2)c5ccccc5,1.6 | |
| CC1=NC(=C(NC1=O)c2ccccc2)c3ccc(CN4CCC(CC4)N5C(=O)Nc6ccccc56)cc3,3.8 | |
| Clc1ccc(N2CCN(CC2)C(=O)COCc3ccccn3)c(Cl)c1,3.47 | |
| CC(C)C[C@H](N1CCC[C@@H](C1)N2C=C(C)C(=O)NC2=O)c3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3,.93 | |
| C[C@H](c1c[nH]cn1)c2cccc(C)c2C,2.79 | |
| OC1CCN(CC1)C(=O)c2ccc(cc2)C(=C3CCN(Cc4cscn4)CC3)c5cccc6cccnc56,1.89 | |
| COc1ccc(cc1)N2Sc3ccccc3C2=O,3.02 | |
| CCC(N(CC1CCNCC1)C(=O)c2ccc(C)cc2)C3=Nc4ccsc4C(=O)N3Cc5ccccc5,1.33 | |
| CC(=O)Nc1nc(CCc2ccc(NC(=N)N)cc2)cs1,-.82 | |
| CN1C[C@H](c2ccccc2)c3cccc(N)c3C1,2.11 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(cc3)C(=O)N4CC[C@@H](C4)N(C)C)ncc2F,2.16 | |
| COc1ccc(NC(=O)c2oc(Nc3ccccc3F)nn2)cn1,3.2 | |
| Cc1ccc(CCCOCCS(=O)(=O)CCCNCCc2ccc(O)c3nc(O)sc23)s1,2.41 | |
| O[C@H](CNC(=O)c1cn2cc(F)ccc2n1)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,3.33 | |
| OC(=O)[C@H](Cc1ccc(CCCCNc2ccccn2)cc1)NC(=O)c3c(Cl)cccc3Cl,.51 | |
| CCNC(=O)c1cc2c(c(cnc2[nH]1)c3cncc(c3)C(=O)NC)n4ccc(n4)C(F)(F)F,2.21 | |
| COc1cc(ccc1Cn2cnc3ccc(NC(=O)CC4CCCC4)cc23)C(=O)NS(=O)(=O)c5ccccc5,.9 | |
| NC(=N)c1cc2c(I)cccc2s1,.74 | |
| Oc1ccc(cc1)C2=CC(=O)c3ccccc3N2,2.34 | |
| CN(C)N(C)C(=O)[C@@]1(Cc2ccccc2)CCCN(C1)C(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)C(C)(C)N,2.1 | |
| Cc1nc(Nc2ncc(s2)C(=O)Nc3c(C)cccc3Cl)cc(n1)N4CCN(CCO)CC4,3.41 | |
| Cc1ccc(CCOCCNS(=O)(=O)CCCNCCc2ccc(O)c3nc(O)sc23)cc1,2.07 | |
| Cc1ccc2NC(=O)OC3(CCN(CCc4nc(oc4C)c5ccccc5)CC3)c2c1,4.2 | |
| CCn1c(SCC(=O)Nc2c(cnn2c3ccccc3)C#N)nnc1c4cccs4,2.1 | |
| Nc1ncnc2c1ncn2Cc3ccccc3,1.53 | |
| CC(C)C[C@@H](CO)NS(=O)(=O)c1ccc(Cl)s1,2.8 | |
| CC(C)OC(=O)N1CCC(CC1)Oc2ncnc(Oc3ccc(cc3F)S(=O)(=O)C)c2C,3.7 | |
| Nc1c(cnn1c2ccc(F)cc2)C(=O)c3cccc(OC[C@@H](O)CO)c3,1.91 | |
| CCC(N(CCCN)C(=O)c1ccc(cc1)C(C)C)C2=Nc3ccsc3C(=O)N2Cc4ccccc4,2.72 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2cccc(c2)C(=O)O)NC(=O)OCc3ccccc3)C(=O)C(F)(F)F,1.2 | |
| Cc1ccc(cc1)C(=O)c2ccc(CC(=O)O)n2C,-1.02 | |
| COc1cc(ccc1Cc2c[nH]c3ccc(NC(=O)CC4CCCC4)cc23)C(=O)NS(=O)(=O)c5ccccc5C,2 | |
| CC(=O)Nc1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,3.04 | |
| COCCNc1nc(N)c2nc(O)n(Cc3ccccc3)c2n1,2.18 | |
| OC(=O)C1=CN(C2CC2)c3cc(N4CCN(CC4)C(=O)CC[N+](=O)[O-])c(F)cc3C1=O,.22 | |
| Cc1ccc(CN2[C@@H]3CC[C@H]2C[C@@H](C3)Oc4cccc(c4)C(=O)N)s1,2.44 | |
| C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc3NC(=O)C=Cc13,3.36 | |
| COc1cc2ncnc(Nc3ccc(F)cc3)c2cc1OC,3.1 | |
| C[C@H](Nc1nc(Nc2ncc(C#N)s2)cc(n1)N3CCOCC3)c4ccc(F)cn4,3.45 | |
| COc1cc(OC)c(cc1NC(=S)NCC(=O)O)S(=O)(=O)N2C(C)CCc3ccccc23,-1.04 | |
| COc1ccccc1CNC(=O)c2ccc3cnccc3n2,1.8 | |
| CC(=O)Nc1ccc2c(c1)c(cn2C)c3cc(NC4CC4)n5ncc(C#N)c5n3,2.94 | |
| CCOc1cc(Nc2nc3c(cc2F)ncn3[C@@H](CO)c4ccc(F)cn4)n[nH]1,2.55 | |
| CCN(CC)CCOc1ccc(cc1)C(O)(Cc2ccc(Cl)cc2)c3ccc(C)cc3,3.98 | |
| CC1=CN([C@H]2CCCN(C2)S(=O)(=O)c3ccc(C(=O)N)c(Oc4cccc(Cl)c4)c3)C(=O)NC1=O,1.96 | |
| NC1=CC2=NNC(=O)N2c3cc(ccc13)c4occc4,2.48 | |
| Clc1ccccc1C(=O)NCC23CC4CC(CC(C4)C2)C3,4.05 | |
| Nc1nccc(n1)c2cccs2,1.75 | |
| CN1CCC(CC1)(C#N)c2cccc3ccccc23,2.73 | |
| COc1cc2ncc(C(=O)N)c(Nc3cccc(Cl)c3Cl)c2cc1OC,3.4 | |
| N\C(=C(\C#N)/c1ccccc1C(F)(F)F)\Sc2ccc(N)cc2,3.3 | |
| CN(C)c1ccc2N=C3C=CC(=[N+](C)C)C=C3Sc2c1,-.88 | |
| CC[C@H](NC(=O)c1c(CS(=O)(=O)C)c(nc2ccccc12)c3ccccc3)c4ccccc4,3.25 | |
| CC(C)NCC(O)COc1ccc(CCOCC2CC2)cc1,.63 | |
| Cc1nsc(C)c1CCC2CCN(CC2)S(=O)(=O)CC3(CCOCC3)N(O)C=O,1.5 | |
| COc1ccc2c(c1)c(c(C)n2CC(=O)O)c3ccnc4cc(Cl)ccc34,1.16 | |
| Nc1nc(OC2CCCC2)nc3c1ncn3[C@@H]4O[C@H](CO)[C@H](Cl)[C@H]4O,2.16 | |
| COc1cc2N(CCN3CCC(CC3)NCc4cc5OCCOc5cn4)C(=O)C=Cc2cn1,.68 | |
| O=C(NCC12CC3CC(CC(C3)C1)C2)c4ccccc4,4.21 | |
| Cc1ccn2c(NC(=O)c3ccccc3)c(nc2c1)c4cccs4,2.87 | |
| Fc1cc(ccc1C2=CCOCC2)N3C[C@H](COc4ccon4)OC3=O,2.61 | |
| CC(C)(C)NC(=O)[C@@H]1CN(Cc2cccnc2)CCN1C[C@@H](O)C[C@@H](Cc3ccccc3)C(=O)N[C@@H]4[C@H](O)Cc5ccccc45,2.9 | |
| OC(=O)COc1cccc(c1)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,1.99 | |
| Oc1cccc(NC(=O)c2ccc(OCCCN3CCCC3)cc2OCc4ccc(F)cc4)c1,3.2 | |
| CC(=O)Nc1ccc(O)cc1,.25 | |
| Cc1cc(NCc2ccccc2)nc3ccccc13,3.69 | |
| Cc1c(cnn1c2ccc(cc2)C(=O)O)C(=O)NC3C4CC5CC(CC3C5)C4,.8 | |
| NC(=O)Nc1sc(cc1C(=O)N[C@H]2CCCNC2)c3cc(F)cc(F)c3,2.18 | |
| COc1ccc(cc1)c2cc(ccc2OCC(=O)O)C(F)(F)F,.29 | |
| Nc1ccccc1NC(=O)c2ccccn2,1 | |
| O=C(Nc1nccs1)c2cccnc2,2.25 | |
| Nc1nc(nc(N)c1Cc2ccccc2F)c3ccccn3,2.12 | |
| COc1ccc2C(=CC(=O)N(CCN3CCC(CC3)NCc4cc5OCCOc5cn4)c2c1)C,1.72 | |
| N#Cc1cnn2c(NC3CC3)cc(nc12)c4cccs4,2.88 | |
| OC(=O)COc1ccc(Cl)cc1c2cccc(c2)C#N,-.25 | |
| CCC(CC)NC(=O)c1cn(nc1NS(=O)(=O)c2ccc(C)cc2)c3ccccc3,2.51 | |
| FC(F)(F)c1nnc2ccc(nn12)N3CCCC3,2.41 | |
| COc1cc2c(Nc3cc(CC(=O)Nc4cccc(F)c4F)[nH]n3)ncnc2cc1OCCCN5CCC[C@@H]5CO,1.96 | |
| c1ccc2ccccc2c1,3.29 | |
| CC(NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4ccccc4,2.17 | |
| O=C1COc2ccc(CNC3CCN(CCN4C(=O)COc5ccc(cc45)c6occc6)CC3)nc2N1,2.19 | |
| CCC(N(CCCN)C(=O)c1ccc(C)cc1)C2=Nc3sccc3C(=O)N2Cc4ccccc4,2.06 | |
| O=C(CN1CCOCC1)Nc2ccc(cc2c3ccccc3)c4cccc5C(=O)C=C(Oc45)N6CCOCC6,3.4 | |
| Cc1onc(CO)c1C(=O)Nc2nccs2,1.53 | |
| Cc1ccnc(NCc2c(O)ccc3ccccc23)c1,4.24 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1nn(Cc3cccc4ccccc34)c2c5ccncc5,4.3 | |
| COc1ccc(C(CN2CCCC2)N(C)C(=O)Cc3ccc(Cl)c(Cl)c3)c(OC)c1,3.07 | |
| CNC(=O)c1ccc(Nc2ncc(F)c(n2)c3cnc(C)n3C(C)C)cc1F,3.31 | |
| COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCCCC4,3.3 | |
| CN[C@H]1CCN(C1)C(=O)c2ccc(Nc3nccc(n3)c4cnc(C)n4C(C)C)cc2,1.22 | |
| Cc1cc(C)n(n1)c2cccc(Cl)c2C#N,3 | |
| Fc1cccc2c3CN(CCc3[nH]c12)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,3.03 | |
| NCCCC(=O)OCCN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1,1.5 | |
| Cn1ccc2c(cccc12)c3nc(CS(=O)(=O)C)cc(n3)N4CCOCC4,2 | |
| Oc1nc2ccccc2nc1NCc3ccccc3,3.3 | |
| CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1CCCN(CCc2ccc(Br)cc2)C1)C(C)(C)C,2.92 | |
| CCCCCCN1CC[C@@]2(C)[C@@H](C)C1Cc3ccc(O)cc23,2.5 | |
| CC(C)NC[C@@H](O)COc1cccc2ccccc12,1.13 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)OCc3ccc(cc3)C(=O)O)C(=O)C(F)(F)F,.84 | |
| Cc1nc(CSc2ccc(Cl)cc2)cc(n1)N3CCOCC3,3.38 | |
| Cc1nc(C)c(nc1C(=O)N)c2ccc3c(CC[C@@]34CC[C@H](CC4)C(=O)O)c2,1.3 | |
| C[C@H]1COCCN1c2nc(N3CCOC[C@@H]3C)c4ccc(nc4n2)c5cccc(c5)C(=O)NCCO,2.49 | |
| Clc1ccc(cc1Cl)[C@]23CNC[C@H]2C3,1.96 | |
| CN1CCN(CC1)c2ccc3N=CN(C(=O)c3c2)c4cc(NC(=O)C5CC5)ccc4C,2.17 | |
| O=C1C=C(OCc2ccccc2)C=CN1c3ccc4c(cnn4CCN5CCCC5)c3,2 | |
| Fc1ccc(cc1)C(=O)C2CCN(CC2)C(=O)NCc3ccccc3,3.15 | |
| CN(C)S(=O)(=O)c1ccc2OCC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,.15 | |
| O\N=C\1/C(=O)N(Cc2ccccc2[N+](=O)[O-])c3ccccc13,2.07 | |
| Cc1ccc(NC(=O)[C@H]2CCCN2S(=O)(=O)c3cccc4cccnc34)c(C)c1,3.9 | |
| Cc1cccc(C[C@H](N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2)C(=O)O)c1,2.84 | |
| Cc1cc(nn1C[C@H](O)CN)c2ccc(Cl)c(c2)C(=O)NCC3(O)CCCCCC3,.57 | |
| CCCSc1nc(ccc1C(=O)N[C@@H]2C3CC4CC2C[C@@](O)(C4)C3)N5CCOCC5,3.2 | |
| COc1cc(OC)c(cc1NC(=O)CCC(=O)O)S(=O)(=O)N(c2ccccc2)c3ccccc3,-.8 | |
| OC1(CCN(CC1)c2ccc3nnc(n3n2)C(F)(F)F)c4ccc(F)cc4,3.5 | |
| Cc1cc(Cl)ccc1OC2CCN(C[C@H](O)CNC(=O)C3=CNC(=O)c4cc(ccc34)S(=O)(=O)C)CC2,2.42 | |
| CC(=O)Nc1cc2c(ccn2c3cc(NC4CC4)n5ncc(C#N)c5n3)cc1C,2.66 | |
| CN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)NCc4ccccc4,3.4 | |
| OC(=O)\C=C\c1cccc(c1)c2cnc3[nH]ccc3c2,.58 | |
| Clc1ccccc1N2CCN(CC2)C(=O)NC3CCCCC3,3.78 | |
| COc1cc(OC)c(cc1NC(=O)C)S(=O)(=O)N2C(C)Cc3ccccc23,1.95 | |
| CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(N3CCN(CC3)c4ccc(cn4)C#N)c(F)c2,1.98 | |
| O=C1Nc2ccc(cc2C1=O)S(=O)(=O)N3CCC[C@H]3COc4ccccc4,2.7 | |
| Clc1cc(Cl)cc(NC(=O)NCC2(CCN(CC3CC3)CC2)c4ccc(cc4)c5cccc(c5)C#N)c1,3.37 | |
| Oc1ccc(CCc2ccc(O)cc2)cc1,3.3 | |
| CC(C)c1ccc(NC(=O)NCCCSC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n3cnc4c(N)ncnc34)cc1,2.5 | |
| CCO[C@@H]1OC(=O)C[C@@H]1NC(=O)[C@@H]2CCCN3N2C(=O)[C@H](CCC3=O)NC(=O)c4nccc5ccccc45,1.16 | |
| CCCSc1ncccc1C(=O)N[C@@H]2[C@@H]3CC4C[C@H]2C[C@@](O)(C4)C3,2.27 | |
| CCCC(C)(C)C[C@@H](N1CCC[C@@H](C1)N2C=C(C)C(=O)NC2=O)c3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3,1.99 | |
| CC(C)(C)NC[C@H](O)COc1nsnc1N2CCOCC2,-.22 | |
| CN(C(CN1CCCC1)c2ccccc2)C(=O)Cc3ccc(Cl)c(Cl)c3,3.38 | |
| [O-][N+](=O)c1ccc2NC(=O)CN=C(c3ccccc3Cl)c2c1,3.72 | |
| CN(CCCc1ccccc1)S(=O)(=O)c2cc(C(=O)N3CCc4ccc(cc4C3)S(=O)(=O)NCCc5ccccc5)c(O)c(O)c2O,.75 | |
| COc1ccc(N(C(C(=O)NC[C@@H](C)O)c2ccccc2F)C(=O)c3ccccc3)c(OC)c1,2.55 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2CCCN(CCc3ccccc3F)C2,2.51 | |
| COc1cc(Nc2ncnc(Nc3c(Cl)ccc4OCOc34)n2)cc(OC)c1OC,3.01 | |
| CCCNC(=O)c1nnc2c(cccc2c1N)c3cnc(OC)nc3OC,3.26 | |
| CN(Cc1ccc(Cl)cc1)C(=O)C2(N)CCN(CC2)c3ncnc4[nH]ccc34,2.8 | |
| Fc1ccc(cc1)S(=O)(=O)Cc2cc(nc(n2)c3ccccn3)N4CCOCC4,1.59 | |
| OC(=O)[C@H](Cc1ccc(NC(=O)Cc2ccc3CCCNc3n2)cc1)NC(=O)c4c(Cl)cccc4Cl,-.63 | |
| OC(=O)C(N1CCO[C@@H](CN2CCC(CC2)Oc3ccc(Cl)c(Cl)c3)C1)c4ccccc4,1.71 | |
| NC(=O)c1cc(sc1N)c2ccccc2,2.7 | |
| OC1=CC(=O)C2=C(O1)c3ccccc3N(C2=O)c4ccccc4,.96 | |
| Clc1ccc(NCCNCC(=O)N2CCC[C@H]2C#N)nc1,.99 | |
| Clc1ccc(OC2CCN(CC2)C3CCN(CC3)C(=O)c4ccc(cc4)c5nn[nH]n5)cc1Cl,1.53 | |
| CCc1[nH]c2nc(Sc3cnc4ccc[n+]([O-])c4c3)nc(N5C[C@@H]6[C@@H](N)[C@@H]6C5)c2c1Cl,2.3 | |
| O=C1NC(=O)c2cc(OCc3ccccc3)ccc12,3.1 | |
| Fc1cc(c(F)cc1Oc2ccc(Cl)cc2c3ccnn3C4CNC4)S(=O)(=O)Nc5ncns5,1 | |
| Clc1cccc(c1)c2cnc3ccc(NC4CCOCC4)nn23,4.3 | |
| CC(C)(C)OC(=O)N1CCN(CC1)c2ccc(OCc3ccc(cc3)S(=O)(=O)C)nn2,2.8 | |
| COc1ccccc1N2CCN(CCCCNC(=O)c3ccc4ccccc4c3)CC2,3.53 | |
| CCOC(=O)\C=C\[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC#C)N2C=CC=C(NC(=O)c3cc(C)on3)C2=O,1.75 | |
| CC[C@@H]1COCCN1c2cc(nc(n2)c3cccc4[nH]ccc34)C5(CC5)S(=O)(=O)C,3 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(cc3)C(=O)N4CC[C@H](C4)N(C)C)ncc2F,2.36 | |
| CC1=C(C(=O)N(C[C@H](N)c2ccccc2)C(=O)N1Cc3c(F)cccc3F)c4ccc5OCOc5c4,2.67 | |
| Oc1ccc(cc1)C2=CC(=O)c3cc(O)ccc3O2,3.3 | |
| CN(C1CCN(Cc2nc3cc(F)ccc3s2)CC1)C(=O)Cc4ccc(cc4)n5cnnn5,2.85 | |
| ONC(=O)CN1C(=O)C(Cc2ccccc12)NC(=O)c3cc4cc(Cl)sc4[nH]3,2.4 | |
| CCN1C=C(C(=O)O)C(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c12,-1.1 | |
| O=C1C=COc2ccccc12,1.4 | |
| CS(=O)(=O)N1CC[C@@H](C1)N(Cc2ccccc2Cl)c3ccc(C#N)c(Cl)c3,4 | |
| Cc1nccn1CC2CCc3c(C2=O)c4ccccc4n3C,1.67 | |
| Oc1ccccc1NC(=O)c2cc(ccc2Cl)[N+](=O)[O-],2.49 | |
| CCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(=O)(=O)N,-.84 | |
| CS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4ocnc34)n2)c1,2.9 | |
| ONC(=O)Cc1ccc(Oc2ccccc2)cc1,2.03 | |
| Cc1cn(C[C@H]2CN(C(=O)O2)c3ccc(C4=CCS(=O)(=O)CC4)c(F)c3)nn1,1.25 | |
| C[C@H](CNCCc1ccncc1)c2c([nH]c3ccc(cc23)C(C)(C)C(=O)N4C5CCC4CC5)c6cc(C)cc(C)c6,4.35 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)N4CCN(CC4)C(=O)CO)n2,1.69 | |
| CCN1CCC[C@H](C1)C(=O)N2CCN(CC2)C(=O)Nc3ccc(Cl)c(Cl)c3,1.6 | |
| Cc1ccc(cc1)c2cc(nn2c3ccc(cc3)S(=O)(=O)N)C(F)(F)F,3.42 | |
| C(Oc1cccc2ccccc12)C3=NCCN3,.68 | |
| CC(C)n1nc(C)c(C(=O)N[C@@H](C)C(C)(C)C)c1NS(=O)(=O)c2ccc(C)cc2,.97 | |
| CCOC(=O)c1ncn2c1CN(C)C(=O)c3cc(F)ccc23,1.1 | |
| CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c3ccccc3,2.5 | |
| CCCCC1=NC2(CCCC2)C(=O)N1Cc3ccc(cc3)c4ccccc4c5nn[nH]n5,1.29 | |
| CCNC(=O)OC[C@@H](C)N(c1cc(Cl)ccc1CO)S(=O)(=O)c2ccc(Cl)cc2,3.4 | |
| C1Oc2ccc(Oc3cc(Oc4ccc(cc4)n5ccnc5)ncn3)cc2O1,3.17 | |
| O=C1NN=C(Cc2ccccc2)c3ccccc13,2.8 | |
| Cc1[nH]c(\C=C\2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NC[C@H](O)CN4CCOCC4,2.22 | |
| COc1ccc(NC(=O)CCc2c(C)nc3nc(C)nn3c2C)cc1,1.4 | |
| Cc1nc(C)c(nc1C(=O)N)c2ccc3c(CC[C@@]34CC[C@H](Cc5nnn[nH]5)CC4)c2,2 | |
| CO[C@H]1CN(Cc2ccc(cc2)C(F)(F)F)CC[C@H]1N(C)C(=O)Cc3ccc(cc3)n4cnnn4,3 | |
| CCOC(=O)c1ccc(OCCC2CCN(CC2)c3ccc(C)nn3)cc1,4.42 | |
| COc1ccc(cc1C(=O)NCc2cccnc2)C(=O)NCc3cccnc3,1.23 | |
| CN(C)CCOc1ccc(cc1)c2cc(C(=O)N)c(NC(=O)N)s2,1.16 | |
| Fc1cccc(COc2ccc(Nc3ncnc4ccc(cc34)c5cccc(c5)N6CCOCC6)cc2Cl)c1,3.2 | |
| Clc1ccc(OC2CCN(CC2)C3CCN(CC3)C(=O)NS(=O)(=O)c4cccc(c4)C#N)cc1Cl,1.81 | |
| Cc1ccc(cc1)c2cc(C(=O)N3CCOCC3)c4cc(C)ccc4n2,3.6 | |
| N[C@@H](Cc1cccs1)C(=O)N[C@@]2(C[C@@H]2c3ccccc3)C#N,1.3 | |
| CCCSc1nc(ccc1C(=O)NC2CCCCC2)N3CCC(CC3)C(=O)O,1.6 | |
| Fc1ccc(cc1)C(COCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)N3CCNCC3,3 | |
| CC(C)(C)C(O)\C(=C/c1ccc(Cl)cc1Cl)\n2cncn2,3.8 | |
| C[C@@H]1C2CCCC1(CCN2C)c3cccc(O)c3,.52 | |
| Fc1cc2N=CNC(=O)c2cc1F,1.5 | |
| CCOc1ccc2C=CC(=O)Oc2c1,2.2 | |
| COc1cc2c(Nc3cnc(NC(=O)c4ccccc4)nc3)ncnc2cc1OCCCN5CCOCC5,2.7 | |
| CN1C(=O)N(C)c2nc[nH]c2C1=O,-.09 | |
| CCCS(=O)(=O)c1ccc(Nc2nccc(n2)c3cnc(C)n3C(C)C)cc1,3.37 | |
| COc1cc(ccc1Cn2ccc3ccc(NC(=O)OC4CCCC4)cc23)C(=O)O,2.1 | |
| Brc1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCCNC(=O)c4cccs4,4.13 | |
| CCOc1ccc(CCNCCCSCCNC[C@H](O)c2ccc(O)c3NC(=O)Sc23)cc1,.41 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)N4CCN(CC4)S(=O)(=O)C)n2,2.57 | |
| OC(=O)CCc1oc(c2ccccc2)c(n1)c3ccccc3,1.2 | |
| C[C@@H](Oc1cccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c12)C(=O)N5CCOCC5,4.14 | |
| COc1ccc(nc1OC)N2CCN([C@H](C)C2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NC4(CC4)C#N,2.3 | |
| CC(C)OC(=O)N1CCC(CC1)Oc2ncnc3c2cnn3c4ccc(cc4F)S(=O)(=O)C,3 | |
| COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(C)[C@H](C)C(=O)N,3.44 | |
| N(c1cccnc1)c2ncnc3ccccc23,1.57 | |
| CCOc1ccc2oc(C(=O)NC(CCSC)c3nc4cnccc4[nH]3)c(C)c2c1,4.31 | |
| COCCOc1ccc(cc1)C(=O)Nc2cc(NC(=O)c3cccc(c3)N(C)C)ccc2C,2.74 | |
| O=C(CSC1=NC2=C(SCC2)C(=O)N1c3ccccc3)Nc4ncc(s4)c5ccccc5,3.95 | |
| CC(C)(C)OC(=O)N1CCN(CC1)c2ncc(OCc3ccncc3C#N)cn2,2.81 | |
| NC(=O)Nc1cc(sc1C(=O)N[C@H]2CCCNC2)c3ccc(cc3)C#N,.61 | |
| CC(C)Cn1cnc2c(N)nc3ccccc3c12,2.52 | |
| Cc1ccc(cc1NC(=O)c2ccc(OCc3ccccn3)cc2)c4ncc(C)n4C,2.67 | |
| C[S+]([O-])c1ccc(\C=C/2\C(=C(CC(=O)O)c3cc(F)ccc23)C)cc1,-.01 | |
| CN1C2CC(CC1C3OC23)OC(=O)C(CO)c4ccccc4,.17 | |
| CN(CCNC[C@H](O)c1ccc(O)c2NC(=O)Sc12)C(=O)CCOCCc3ccccc3,1.21 | |
| Cc1oc(nc1CCOc2ccc(C[C@H](Nc3ccccc3C(=O)c4ccccc4)C(=O)O)cc2)c5ccccc5,3.5 | |
| CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(F)(F)F,3.59 | |
| CCN1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c3C1=O)c6cc(cn6C)C#N,4.13 | |
| CN(C)c1ccnc2sc(C(=O)N)c(N)c12,1.7 | |
| CC1=C(C(=O)c2cc(O)c(O)c(Cc3ccccc3)c2C1=O)C4=C(C)C(=O)c5c(Cc6ccccc6)c(O)c(O)cc5C4=O,2.73 | |
| CN(C)CCCOc1ccc(cc1)c2cc(C(=O)N)c(NC(=O)N)s2,.64 | |
| COc1cccc(c1)c2cc3c(N[C@H]4CCCNC4)ncc(C(=O)N)c3s2,1.82 | |
| COc1ccc(cc1)C(CN(C)C)C2(O)CCCCC2,.99 | |
| Cc1cc(CN2CCC2)cnc1c3ccc(cc3)C(=O)Nc4ccccc4N,1.18 | |
| Cc1oc2C=NN(B(O)c2c1)S(=O)(=O)c3ccc(C)cc3,-.28 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)C(=O)N4CCN(C)CC4)n2,2.1 | |
| Oc1ccc(CCNCCNS(=O)(=O)CCOCCCc2ccccc2)c3sc(O)nc13,2.22 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4cc(ccn34)C#N)N5CCN(CC5)C(=O)C,2.3 | |
| COC(=O)c1ccc(cc1)C(C)N2NC(=O)C3=C(C2=O)C(=O)c4ccc(Cl)cc4N3,1.3 | |
| NC(=O)C([C@@H]1CCN(CCc2ccc3OCCc3c2)C1)(c4ccccc4)c5ccccc5,2.79 | |
| CCC(N(CCCN)C(=O)c1ccc(C)cc1)C2=Nc3ccsc3C(=O)N2Cc4ccc(C)cc4,1.69 | |
| NCC[C@@H](Oc1nc(ccc1C#N)C(F)(F)F)c2oncc2,-.49 | |
| Cc1ccc2c(c1)c(c(C)n2CC(=O)O)c3ccnc4cc(ccc34)C(F)(F)F,1.78 | |
| CN(C)CCN(Cc1ccccc1)c2ccccn2,1.28 | |
| COc1ncc(cc1NS(=O)(=O)c2ccc(F)cc2F)c3ccc4nccc(c5ccnnc5)c4c3,2.5 | |
| Clc1ccc(OC2CCN(CC2)C3CCN(CC3)C(=O)NS(=O)(=O)c4ccccc4Cl)cc1Cl,1.93 | |
| CC(CCc1ccccc1)NCC(O)c2ccc(O)c(c2)C(=O)N,1.06 | |
| CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC,.34 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)NCc3ccccn3)C(=O)C(F)(F)F,2.15 | |
| OC(=O)Cc1ccccc1Nc2c(Cl)cccc2Cl,1.08 | |
| COc1ccccc1CCNCc2ccc(CCNC[C@H](O)c3ccc(O)c4NC(=O)Sc34)cc2,.8 | |
| NC(=O)C1=CN(Cc2ccc(Cl)cc2Cl)C(=O)C=C1,2.36 | |
| CCc1cc(ccn1)C(=S)N,1.52 | |
| COc1cccc(NC(=O)c2cccc(Cc3c(C)nn(CCO)c3c4ccccc4)c2)c1,4.29 | |
| COc1ccc(CC(=O)Nc2nc3ccccc3[nH]2)cc1,2.9 | |
| COc1cc(OC)cc(c1)c2cc3cnc(N)nc3nc2N,2.14 | |
| COc1ccc(cc1CO)c2ccc3c(nc(nc3n2)N4C[C@@H](C)O[C@@H](C)C4)N5CCOCC5,3.25 | |
| CC(=O)N1CCN(CCOc2ccc(cc2)C3(O)CCN(CC3)c4ccc5nnc(n5n4)C(F)(F)F)CC1,2.2 | |
| Clc1ccc2nc(ccc2c1C(=O)NCC34CC5CC(CC(C5)C3)C4)N6CCC[C@@H](C6)NCCc7nnn[nH]7,3.08 | |
| Cc1c(Sc2ccc(Cl)cc2)c3ccc(Cl)cc3n1CC(=O)O,2.51 | |
| Cc1nc2c(cnn2c(O)c1Cc3ccccc3)C#N,.68 | |
| CNC(=O)c1ccc(Nc2nccc(n2)c3cnc(C)n3C(C)C)cc1F,2.95 | |
| CC12CCC3C(CCC4=CC(=O)CCC34C)C1CCC2O,3.3 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3ccccc3C(F)(F)F)c2C(=O)N4CCCC4,3.8 | |
| O=C1N2CCS(=O)(=O)C2=Nc3ccccc13,.8 | |
| CCOC(=O)c1c(C)n(Cc2occc2)c3ccc(O)cc13,3.5 | |
| Cc1cccc(NC(=O)c2ccc(c3ccccc3)c(c2)C#N)n1,3.71 | |
| CONC(=O)c1cnc(s1)N2CCC(CC2)NC(=O)c3[nH]c(C)c(Cl)c3Cl,3.1 | |
| NC(=O)c1ccc(cc1)c2cc3c(N[C@H]4CCCNC4)ncc(C(=O)N)c3s2,.28 | |
| COCc1c(nc(C(C)C)c(\C=C\[C@@H](O)C[C@@H](O)CC(=O)O)c1c2ccc(F)cc2)C(C)C,1.72 | |
| [O-][N+](=O)c1ccc2C(=O)C(=O)c3ccccc3c2c1,2.56 | |
| CCC[C@H](CO)Nc1nc(SCc2ccccc2)nc3nc(N)sc13,3.8 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(C(=O)N(C)C)c(C)c3)ncc2F,2.86 | |
| CNC(=O)C1(CCN(CC[C@H](CN(C)C(=O)c2c(OC)c(cc3ccccc23)C#N)c4ccc(Cl)c(Cl)c4)CC1)N5CCCNC5=O,2.2 | |
| Oc1cccc(NC(=O)c2ccc(OCCCN3CCCC3)cc2OCc4cccnc4)c1,1.59 | |
| CC12CC3CC(C)(C1)CC(N)(C3)C2,.06 | |
| CO[C@H]1CN(CCN2C(=O)C=Nc3ccc(OC)cc23)CC[C@@H]1NCc4cc5OCCOc5cn4,1.25 | |
| Brc1ccc(s1)S(=O)(=O)NCC(N2CCCCCC2)c3ccccc3,3.52 | |
| Cc1cc(Nc2ccc(F)cc2)nc(N)n1,2.08 | |
| CC(=O)Nc1ccccn1,.5 | |
| Clc1ccc(cc1)c2oc(cc2)C(=O)Nc3ccc(cc3)N4CCNCC4,2.4 | |
| Nc1cc(nc(N)[n+]1[O-])N2CCCCC2,.77 | |
| NC1(CCC1)c2ccc(cc2)c3c(ccn4ccnc34)c5ccccc5,2 | |
| Oc1ccc(CCNCCS(=O)(=O)CCCOCCc2nccc3ccccc23)c4sc(O)nc14,2.35 | |
| CCOC(=O)c1ccccc1c2csc(NS(=O)(=O)c3ccc(Cl)cc3)n2,2.43 | |
| CN1CCN(CC1)C(=O)c2cc(sc2NC(=O)N)c3ccccc3,2.17 | |
| Oc1ccc(cc1)N2C(=O)c3ccccc3C2=O,2 | |
| COCCNc1nc(NCc2ccccc2F)c3sccc3n1,3.4 | |
| Cn1cc(cc1C=O)C(=O)CCCCOc2ccc(cc2)C(=O)O,.14 | |
| Nc1ccccc1NC(=O)c2ccc(CNC(=O)OCc3cccnc3)cc2,1.26 | |
| Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(C)c4Cl,2.2 | |
| CN1CCC(CC1)n2cc(cn2)c3cnc(N)c(c3)c4oc5cc(F)ccc5n4,3.35 | |
| C[C@H](Nc1nc(Nc2cc(C)[nH]n2)cnc1C#N)c3ncc(F)cn3,1.96 | |
| CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1CCCN(CCc2ccc(C)cc2)C1)C(C)(C)C,2.05 | |
| CC(C)[C@@H](CN1CCCCC1)N(C)C(=O)Cc2ccc(Cl)c(Cl)c2,2.87 | |
| COc1ccc(cc1OC)C(=O)Nc2cccc(NC(=O)c3ccc(OC)c(OC)c3)n2,3.5 | |
| COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCN4CCCC4,3.28 | |
| CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(c(F)c2)n3ccnc3,.7 | |
| CN1SC(=O)c2cc(ccc12)S(=O)(=O)N,.3 | |
| Nc1nc(OC2CCCC2)nc3c1ncn3[C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O,.79 | |
| Cc1ncsc1CCOCCCS(=O)(=O)CCNCCc2ccc(O)c3nc(O)sc23,1.44 | |
| COc1ccccc1CN(C)Cc2cccc(CCNC[C@H](O)c3ccc(O)c4NC(=O)Sc34)c2,1.52 | |
| OC1CCN(CC1)C(=O)CN2C(=O)C(Cc3ccccc23)NC(=O)c4cc5cc(Cl)sc5[nH]4,2.86 | |
| C(Cc1nc2ccccc2[nH]1)Cc3nc4ccccc4[nH]3,3.5 | |
| Cc1ccc2c(c1)c(Sc3ccccc3Cl)c(C)n2CC(=O)O,1.71 | |
| Oc1ccc(cc1)c2ccc3cc(O)ccc3n2,3.1 | |
| CN1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c6oc(cc6C)C#N)c3C1=O,4.34 | |
| CO[C@H]1CN(CCN2C(=O)C=Nc3ccc(OC)cc23)CC[C@H]1NCc4ccc5OCC(=O)Nc5n4,.51 | |
| CCN(C1CCN(CC[C@H](N2CCN(CC2)S(=O)(=O)C(F)(F)F)c3ccccc3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,2.86 | |
| NC(=O)c1cccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)n1,1.71 | |
| NC1=NC(=CC(=O)N1)CCc2cccc(Br)c2,2.52 | |
| COc1ccc(C[C@@H](C)NC[C@H](O)c2ccc(O)c(NC=O)c2)cc1,.42 | |
| OC[C@H](O)CN1C(=O)C(Cc2ccccc12)NC(=O)c3cc4cc(Cl)ccc4[nH]3,3.4 | |
| CC(=O)C1=C(C)c2cnc(Nc3ccc(cn3)N4CCNCC4)nc2N(C5CCCC5)C1=O,.8 | |
| CC[C@H](NC(=O)c1c([S+](C)[O-])c(nc2ccccc12)c3cccc(F)c3)c4ccccc4,3.14 | |
| CC(C)C[C@H](CO)Nc1nc(SCc2ccccc2)nc3NC(=O)Sc13,4.2 | |
| CC(=O)N1CCN(CC1)c2ccc(NC(=O)c3oc(Nc4ccccc4F)nn3)cc2,2.51 | |
| CC1=C(C(=O)N(C[C@H](N)c2ccccc2)C(=O)N1Cc3c(F)cccc3F)c4ccccc4F,2.76 | |
| OS(=N)(=O)Cc1noc2ccccc12,.55 | |
| Clc1ccc2[nH]ccc2c1,3.28 | |
| CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)c2cc3cc(F)ccc3[nH]2,3.5 | |
| COc1cc(NC(=O)Nc2cccc(CNC(=O)O[C@H]3CCOC3)c2)ccc1c4ocnc4,3.6 | |
| CCN1C(=O)N(CC)c2[nH]c(nc2C1=O)c3ccccc3,3.3 | |
| CN(C)C(=O)N[C@@H]1CC[C@@H](CCN2CCN(CC2)c3ccc(Cl)cc3)CC1,2.81 | |
| Clc1ccc(cc1)S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,2.59 | |
| CN1C(=O)NC(=O)C(C)(C2=CCCCC2)C1=O,1.5 | |
| COc1cc(Nc2nccc(Oc3cnc4ccccc4c3)n2)cc(OC)c1OC,3.41 | |
| Clc1ccc2N(C3CCN(CCCN4C(=O)Nc5ccccc45)CC3)C(=O)Nc2c1,3.45 | |
| COc1cc(cc(OC)c1O)[C@H]2[C@@H]3C(COC3=O)C(O[C@@H]4O[C@@H]5CO[C@@H](C)O[C@H]5[C@H](O)[C@H]4O)c6cc7OCOc7cc26,.91 | |
| CC1=C(C(=O)Oc2cc(O)ccc12)c3ccc(O)cc3,2.8 | |
| CCN1C=C(C(=O)O)C(=O)c2cc(F)c(cc12)N3CCNCC3,-.87 | |
| COc1cc(OC)c(cc1NC(=O)C)S(=O)(=O)N(C(C)C)c2ccccc2,1.6 | |
| COC(=O)c1c(O)cccc1OC\C=C\c2ccc(F)c(c2)c3onc(c3)C(=O)O,.66 | |
| Nc1nccc(n1)c2c[nH]c3ccccc23,1.68 | |
| OC(=O)c1ccc(cc1)n2ncc(C(=O)NC3C4CC5CC(CC3C5)C4)c2C(F)(F)F,1.5 | |
| Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccncc4,.3 | |
| CCC(N(CCCN)C(=O)c1ccc(C)cc1)C2=Nc3ccsc3C(=O)N2Cc4ccc(OC)cc4,2.15 | |
| Cc1cc(nc(n1)n2ccnc2)N3CCC[C@@H]3C(=O)NCCc4ccc5OCOc5c4,2.5 | |
| CC(C)c1c(cnn1c2ccc(cc2)C(=O)O)C(=O)NC3C4CC5CC(CC3C5)C4,1.15 | |
| CCn1cnc2cnc(c3ccc(cc3)C4(N)CCC4)c(c5ccccc5)c12,2 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)C(=O)N(C)C)n2,2.45 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3cncc4ccccc34)c2C(=O)N5CC[C@@H](O)C5,1.74 | |
| OCCNC(=O)COc1ccc(OCCNCC(O)COc2ccccc2)cc1,.42 | |
| CCc1cc(C(=O)N[C@@H](Cc2cccc(Cl)c2)C(=O)NCC#N)n(C)n1,2.6 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)C(=O)NC4CC4)n2,3.06 | |
| Cc1cnccc1COc2cnc(nc2)N3CCN(CC3)C(=O)OC(C)(C)C,3.8 | |
| C=CCCCCCCCCC(=O)N[C@H]1CCC(=O)NC1=O,2.64 | |
| COc1cc2nnc(C(=O)N)c(Nc3cc(C)ccc3F)c2cc1N4CCN(C)CC4,2.57 | |
| O[C@H](CNC(=O)c1cnnc2ccccc12)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,3.28 | |
| CCCCc1nc2c(N)nc3ccccc3c2n1Cc4ccccc4,4.17 | |
| COc1ccccc1CNC(=O)NS(=O)(=O)c2ccc(Cl)cc2,.87 | |
| Oc1cccc(NC(=O)c2ccc(OCCCN3CCCC3)cc2OCc4cscn4)c1,1.56 | |
| CC(C)(C)OC(=O)N1CCN(CC1)c2ncc(OCc3c(F)cncc3F)cn2,3.7 | |
| Clc1ccc(cc1)C(=O)CN2C3=NCCN3c4ccccc24,2.62 | |
| COc1cc(C)c(c(C)c1)S(=O)(=O)N(C)CCOCC(=O)N2CCC(CC2)C3CCN(C)CC3,.3 | |
| CCC(CC)NC(=O)c1cnn(c1NS(=O)(=O)c2ccc(cc2)c3ocnc3)c4ccccc4,.8 | |
| CC1=CN([C@H]2CCCN(C2)S(=O)(=O)c3cccc(Oc4ccccc4)c3)C(=O)NC1=O,2.32 | |
| COc1nccnc1NS(=O)(=O)c2ccc(N)cc2,-.65 | |
| NC(=O)c1cnc(N[C@H]2CCCNC2)c3cc(sc13)c4ccc(Cl)c(F)c4,2.76 | |
| CC(=O)Nc1cccc2c1c(c(C)n2CC(=O)O)S(=O)(=O)c3ccc(Cl)cc3,.4 | |
| CCCNc1nc(ccc1C(=O)NC2CCCCC2)N3CCC[C@@H](CC(=O)O)C3,2.33 | |
| NC1CCc2cc(OC(=O)c3ccccc3)c(OC(=O)c4ccccc4)cc2C1,2.6 | |
| CC(C)C(=O)Nc1ccc2C(=O)NC(=O)c2c1,1.55 | |
| Cc1ccc(cc1)C(=O)c2cc(O)c(O)c(c2)[N+](=O)[O-],.74 | |
| COc1cc(F)ccc1c2cncc(CNC(C)C)c2,1.5 | |
| Cc1c(Oc2ccc(Cl)cc2)c3cc(F)ccc3n1CC(=O)O,1.26 | |
| COc1cccc2c1c(NS(=O)(=O)c3ccc(Cl)s3)nn2Cc4cccc(CNC(=O)C(C)(C)O)c4,2.09 | |
| CC(=O)Nc1cc(CN2C(=O)N(C(=O)C2(C)C)c3ccc(SC(F)(F)F)cc3)ccn1,2.93 | |
| COc1ccc2SCC(=O)N(CCN3CCC(CC3)NCc4cc5OCCOc5cn4)c2c1,1.78 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4c(CO)cccn34)N5CCN(CC5)C(=O)C,3.1 | |
| CCOc1ccc(cc1)N2C(=O)c3ccccc3N=C2[C@@H](C)N(Cc4cccnc4)C(=O)Cc5ccc(cc5)C(F)(F)F,4.25 | |
| CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)c2ccccc2,3.65 | |
| Brc1ccccc1C(=O)NCC23CC4CC(CC(C4)C2)C3,4.15 | |
| COc1ccc(cc1)c2nc3c(NCCCNC(=O)C4CCCC4)c(cnc3[nH]2)C(=O)N,3.13 | |
| CN1C(=O)CC(C1=O)c2ccccc2,.68 | |
| [O-][N+](=O)c1ccc2[nH]c(nc2c1)c3ccccn3,2.8 | |
| c1ccc(cc1)C#Cc2n[nH]c3ccccc23,4.31 | |
| CSc1ccc(cc1)C(=O)C(C)(C)N2CCOCC2,3.49 | |
| CCN1C(=O)C=Cc2cnc(Nc3ccc(OC)c(OC)c3)nc12,2.7 | |
| CN(CCOc1ccc(NS(=O)(=O)C)cc1)CCc2ccc(NS(=O)(=O)C)cc2,.6 | |
| CCOc1nc2cccc(C(=O)O)c2n1Cc3ccc(cc3)c4ccccc4c5nnn[nH]5,.3 | |
| CCN1CCC[C@@H](CN2CCN(CC2)C(=O)Nc3ccc(Cl)c(Cl)c3)C1,1.94 | |
| CC(C)N1C(=O)N(C)C(=O)c2c1sc(Cc3ccccc3C(F)(F)F)c2C(=O)N4CCS(=O)(=O)C4,2.55 | |
| COc1cc(OC)cc(c1)C2=CC=C(NC(=O)OCc3ccccc3)C(=O)N2CC(=O)NC(C(C)C)C(=O)C(F)(F)F,2.26 | |
| COc1cc2c(Nc3ncc(NC(=O)c4ccccc4)cn3)ncnc2cc1OCCCN5CCOCC5,2.32 | |
| CCNC(=O)c1cc2c(c(cnc2[nH]1)c3cncc(c3)C#N)n4ccc(n4)C(F)(F)F,2.62 | |
| CCS(=O)(=O)c1ccc(c(Cl)c1)c2cc(Cl)ccc2OCC(=O)O,-.43 | |
| CCCOc1nc(ccc1C(=O)NC2CCCCC2)N3CCC[C@@H](CC(=O)O)C3,2.81 | |
| CNC(=O)c1ccc(cc1)c2cc(C(=O)N[C@H]3CCCNC3)c(NC(=O)N)s2,.7 | |
| CC(C)(C)OC(=O)N1CCN(CC1)c2ccc(OCc3ccc(cc3)S(=O)(=O)C)nc2,3.1 | |
| COc1cnc(nc1Oc2ccc(F)cc2F)c3ccccn3,3.1 | |
| CN1CCN(CC1)c2ccc3nc([nH]c3c2)C4=C(N)c5c(F)cccc5NC4=O,3.45 | |
| CN(C(=O)C)c1ccc2ccn(c3cc(NC4CC4)n5ncc(C#N)c5n3)c2c1,2.9 | |
| COc1cc2ncnc(Nc3cc(NC(=O)c4ccnc(c4)N5CCOCC5)ccc3C)c2cc1OCCN(C(C)C)C(C)C,3.5 | |
| Cc1cc(O)nc(n1)n2nc(C)c(Oc3ccccc3O)c2C,1.4 | |
| NC(=O)c1c(N)sc2CCCCc12,1.84 | |
| Fc1ccc(C2CCN(CC2)C(=O)COCc3ccncc3)c(Cl)c1,2.7 | |
| FC(F)(F)c1nnc2ccc(nn12)N3CCCCCC3,3.29 | |
| OCCN(C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1)c3ccccc3,3.37 | |
| Cc1ccc(NC(=O)c2ccnc(c2)N3CCOCC3)cc1NC(=O)c4ccc(OCc5ccccn5)cc4,3.47 | |
| COc1ccc(OC)c(CNc2[nH]nc3cccc(Oc4ccc(cc4)S(=O)(=O)C)c23)c1,3.71 | |
| CCN(C1CCN(CC[C@H](c2ccc(cc2)S(=O)(=O)C)c3cc(F)cc(F)c3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,2.2 | |
| Nc1cccc(CCc2ccc3cc[nH]c3c2)n1,2.8 | |
| CNc1nc2ccccc2n1Cc3sc4N(CC(C)C)C(=O)N(C)C(=O)c4c3C(=O)N5C[C@H](O)CO5,1.77 | |
| CN1CCN(CC(=O)Nc2c(cnn2c3ccccc3)C#N)CC1,0 | |
| Cc1cc(Oc2ccnc(Nc3ccc(cc3)S(=O)(=O)N)c2)c(nc1C)c4ccccn4,2.34 | |
| CCCc1nn(C)c2C(=O)NC(=Nc12)c3cc(ccc3OCC)S(=O)(=O)N4CCN(C)CC4,2.8 | |
| CN(C)CCOc1ccc(cc1)c2oc3ncnc(NC[C@@H]4CCCO4)c3c2c5ccccc5,3.6 | |
| CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O,2.9 | |
| CCN(CCCOCCOCCc1ccccc1)CCc2ccc(O)c3nc(O)sc23,2.45 | |
| Fc1ccccc1Nc2oc(nn2)C(=O)Nc3ccc(N4CCOCC4)c(F)c3,3.6 | |
| CC1=NS(=O)(=O)c2cc(Cl)ccc2N1,1.05 | |
| CN(Cc1oc2ccccc2c1C)C(=O)\C=C\c3cnc4NC(=O)CCc4c3,2.36 | |
| COc1ccc(cc1Oc2cccc(Cl)c2)S(=O)(=O)N3CCC[C@@H](C3)N4C=C(C)C(=O)NC4=O,2.73 | |
| CCOC(=O)C1=C(C)NC(=C([C@H]1c2cccc3C(=O)C=C(C)Oc23)C(=O)C)C,2.63 | |
| Nc1nc2OC(COc3ccccc3)Cc2c(N)c1C#N,2.08 | |
| COc1ncc(cn1)c2cccc3OC[C@H](Cc23)NC(=O)c4ccc(OCC(F)(F)F)nc4,4.3 | |
| Fc1ccc(F)c(NS(=O)(=O)c2ccc(Cl)cc2)c1,2.9 | |
| COC(=O)N1CCN([C@H](CN2CCCC2)C1)C(=O)Cc3ccc(Cl)c(Cl)c3,2.05 | |
| CCN(C(=O)Nc1ccccc1)c2ccccc2,3.1 | |
| Clc1ccc2[nH]c(cc2c1)C(=O)N3CCNCC3,1.65 | |
| O=C(Nc1cccnc1C(=O)NCC2CCOCC2)c3cccc4ccccc34,4.4 | |
| COc1cnc(nc1NC(C)C)c2ccccn2,2.01 | |
| CCCCN(CCNCCc1ccc(O)c2NC(=O)Sc12)C(=O)CCOCCc3ccccc3,3 | |
| CCN(CC)CCNC(=O)c1cc(ccc1OC)S(=O)(=O)C,-.9 | |
| CC(C)(CS(=O)(=O)N1CCN(CC1)c2ccc(F)cc2)N(O)C=O,1.07 | |
| CC(C)N1CCC[C@H](CN2C(=O)c3cc(ccc3N=C2C(C)C)c4ccc(F)cc4)C1,3.6 | |
| COCCN1CCC(Cc2ccc(cc2)C(=O)NCc3cnc(nc3NCC(C)(C)C)C#N)CC1,3.5 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cn3c(C)nc4ccccc34)c2C(=O)N5CC[C@@H](O)C5,1.34 | |
| COc1cc(OC)c(cc1NC(=O)C)S(=O)(=O)N2C(C)CCc3ccccc23,1.97 | |
| Brc1ccc(s1)N2C[C@@]3(CN4CCC3CC4)OC2=O,2 | |
| OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1\C=C\3/CCN(C3=O)c4ccccc4,1.85 | |
| CCN(C1CCN(CC[C@H](c2ccc(cc2)S(=O)(=O)C)c3cc(F)cc(Cl)c3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,2.71 | |
| CO[C@@H]1CN(CCN2C(=O)C=Cc3ccc(cc23)C#N)CC[C@H]1NCc4ccc5OCC(=O)Nc5n4,.81 | |
| CNC1CCN(C1)c2ccc(NC(=O)c3ccc(cc3)c4ccccc4)cn2,2.35 | |
| FC1(F)Oc2ccc(\C=C\3/SC(=O)NC3=O)cc2O1,2.8 | |
| C[C@H](NC(=O)C)c1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,3.17 | |
| OC(=O)COc1ccc(cc1c2ccccc2)c3nccs3,-.16 | |
| O[C@H](CNC(=O)C1=NNC(=O)c2ccccc12)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,3.69 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)NCc3cc[n+]([O-])cc3)C(=O)C(F)(F)F,1.13 | |
| COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)\CCC(=O)OCCN3CCOCC3,2.26 | |
| CC(=N)NCc1ccccc1,-.28 | |
| OC1CS(=O)(=O)CC1N2CCC(CC2)c3ccccc3,1.4 | |
| COc1ccc2[nH]c(cc2c1)C(=O)N3CCN(C)CC3,1.62 | |
| CC(C)C1NCCc2c1sc3ccccc23,2.8 | |
| Nc1nc(Nc2ccc(cc2)S(=O)(=O)N)nn1C(=O)c3c(F)cccc3F,1.87 | |
| CCCCCc1ccc(cc1)c2nnc(N)s2,4.13 | |
| Cc1sc2ncnc(SCC(=O)N3CCCC3)c2c1C,2.89 | |
| OC(=O)[C@H](Cc1cccc(OCCCNc2ccccn2)c1)NC(=O)c3c(Cl)cccc3Cl,.16 | |
| Cc1ccc(cc1)S(=O)(=O)Nc2c(C(=O)NC3CCOCC3)c(C)nn2c4ccccc4,.16 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4cc(Cl)ccn34)N5CCN(CC5)C(=O)C,4.2 | |
| Cc1cc(F)ccc1OC2CCN(CC3CCN(CC3)[C@@H](Cc4ccc(F)cc4)C(=O)O)CC2,1.81 | |
| FC(F)(F)c1nnc2ccc(NCn3nnc4ccccc34)nn12,2.34 | |
| C[C@@H]1N[S@@](=O)(=NC1=O)c2cccc(c2)c3cccc(c3)C#N,.4 | |
| CCCSc1ncccc1C(=O)N(C)C2CCOCC2,1.63 | |
| CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)O,.03 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)C)C(=O)C(F)(F)F,1.78 | |
| CN(C)CCCN1c2ccccc2CCc3ccc(Cl)cc13,3.36 | |
| COc1ccc(N(C(C(=O)NC[C@@H](C)O)c2ccccc2F)C(=O)c3occc3Cl)c(OC)c1,2.18 | |
| OC(=O)c1ccccc1C2=C3C=CC(=O)C=C3Oc4cc(O)ccc24,0 | |
| Oc1nc2ccccc2c(O)c1c3ccccc3,.73 | |
| COc1ccc(OC)c(c1)C(O)CNC(=O)CN,-.71 | |
| CN1CCN(CC1)c2ccc3N=CN(C(=O)c3c2)c4cc(NC(=O)c5cccnc5)ccc4C,1.5 | |
| COc1ccc(cc1CO)c2ccc3c(nc(nc3n2)n4ccnc4)N5CCOC[C@@H]5C,2.6 | |
| C[C@H](C(=O)O)c1cccc(c1)C(=O)c2ccccc2,-.06 | |
| CN1CCN(CC1)c2ccc3N=CN(C(=O)c3c2)c4cc(NC(=O)c5cncs5)ccc4C,2.11 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(C(=O)N(C)C)c(F)c3)ncc2F,3.14 | |
| COC(=O)CCC(=O)Nc1ccc2c(c1)C(=O)C(=O)c3cc(NC(=O)CCC(=O)OC)ccc23,2.67 | |
| CCS(=O)(=O)c1ccc(Oc2c(C)n(CC(=O)O)c3ccc(cc23)C(F)(F)F)cc1,.29 | |
| O=C(NC1CCCCC1)C2CCCN(C2)S(=O)(=O)c3cccs3,2.93 | |
| NC1(CCN(CC1)c2ncnc3[nH]ccc23)C(=O)NC(CS(=O)(=O)N)c4ccc(Cl)cc4,2.2 | |
| CCC(N1NC(=O)C2=C(C1=O)C(=O)c3ccc(Cl)cc3N2)c4ccncc4,.6 | |
| O=C(Nc1ccc(nc1)N2CCOCC2)c3oc(Nc4cccc(OCc5cccnc5)c4)nn3,3.3 | |
| CCOC(=O)c1ccc(OCCC2CN(CCO2)c3ccc(C)nn3)cc1,2.7 | |
| Cc1nc(C)c(nc1C(=O)N)c2ccc3c(CC[C@@]34CC[C@H](CC(=O)O)CC4)c2,1.5 | |
| COC[C@@H](O)CN1C(=O)C=NN(C1=O)c2ccc(Cl)c(c2)C(=O)NCC3(O)CCCCCC3,1.44 | |
| Nc1nc2nc(SCc3ccccc3)nc(N)c2s1,3.1 | |
| CCN(C1CCN(Cc2ccc(cc2)C(F)(F)F)CC1)C(=O)Cc3ccc(cc3)S(=O)(=O)C,2.9 | |
| COc1cc(O)c(C(CC(=O)N2CC(C)CC(C)C2)c3ccc4OCOc4c3)c(OC)c1,4.3 | |
| CCNc1nc(N)c(s1)C(=O)c2ccc(Cl)s2,3.63 | |
| CS(=O)(=O)c1ccc(c(Cl)c1)c2cc(ccc2OCC(=O)O)C(F)(F)F,-.52 | |
| Oc1ccc(cc1)N2C(=O)c3ccc(O)cc3C2=O,1.8 | |
| C1CCC(CC1)NC2CCCCC2,-.38 | |
| CN1CC=CCC(C1)c2ccc(Cl)c(Cl)c2,3.32 | |
| Oc1ccc(Br)cc1C(=O)C(=O)c2cc(Br)ccc2O,3.85 | |
| CNc1c(cnc2[nH]c(nc12)c3ccc(OCCN4CCOCC4)cc3)C(=O)N,2.14 | |
| CC[C@H](CO)Nc1nc(SCc2ccccc2)nc3nc(N)sc13,3.27 | |
| C[C@H](NC(=O)c1c(C)nn(c1NS(=O)(=O)c2ccc(cc2)C(F)(F)F)c3ccc(F)cc3)C(C)(C)C,2.35 | |
| Nc1nc2nc(SCc3cccc(F)c3F)nc(O)c2s1,2.5 | |
| CC(N)COc1c(C)cccc1C,.62 | |
| CCCCC(O)c1[nH]c2cc(C)c(cc2c1CCc3ccccc3)C(=O)O,2.59 | |
| CC(C(=O)Nc1ccc(Cl)cc1)c2ncc(cc2Cl)C(F)(F)F,4.19 | |
| CN(CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c3ccccc3)C(=O)O)cc1)c4ccccn4,2.15 | |
| CN(C)CC(O)COc1ccc(Nc2nccc(Nc3ccccc3)n2)cc1,1.58 | |
| C(CN1CCCC1)Oc2ccc(Nc3ncc4cc(ccc4n3)c5ccncc5)cc2,2.66 | |
| OC(=O)C1=CN(C2CC2)c3cc(N4CCNCC4)c(F)cc3C1=O,-.96 | |
| CN(C)C(=O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)c2cc3cc(Cl)ccc3[nH]2,3.6 | |
| CO[C@H]1CN(CCN2C(=O)C=Cc3ccc(cc23)C#N)CC[C@@H]1NCc4cc5OCCOc5cn4,1.05 | |
| CN(C)CCCC1(OCc2cc(ccc12)C#N)c3ccc(F)cc3,1.56 | |
| CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1CCCN(CCc2ccc(cc2)[N+](=O)[O-])C1)C(C)(C)C,1.54 | |
| CCc1nc2c(N)nc3ccccc3c2n1CC(C)C,2.55 | |
| COc1ccc(cc1)c2nc3c(NCCCNC(=O)C4CC4)c(Br)cnc3[nH]2,1.71 | |
| CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(cc12)S(=O)(=O)N,.27 | |
| CCCNC(=O)c1nnc2c(cccc2c1N)c3cnccc3OC,2.83 | |
| CC(N)Cc1c[nH]c2ccc(OCc3cccs3)cc12,.48 | |
| C1CC2(CCN1)OC(c3ccccc3)c4ccccc24,.75 | |
| COc1cc(ccc1Nc2ncc(Br)c(n2)c3cnc4ccccn34)N5CCN(CC5)C(=O)C,3.7 | |
| CCN(C1CCN(CC[C@@H](c2ccccc2)c3ccc(cc3)S(=O)(=O)C)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,1.38 | |
| CN1CCN(CC1)C2=Nc3ccccc3Oc4ccc(Cl)cc24,3.24 | |
| COc1cc(O)c(cc1NC(=O)CCC(=O)O)S(=O)(=O)N2C(C)CCc3ccccc23,-.27 | |
| Cn1ncc2C(=O)NC(=Nc12)c3ccccc3,1.61 | |
| CN(C)CCCn1c2CCCCCCc2c3ccccc13,2.96 | |
| COc1ccc(cc1)C2=COc3cc(O)ccc3C2=O,3.05 | |
| NC(=O)c1cccnc1Oc2ccccc2,1.13 | |
| N(c1ccccc1)c2ccnc(Nc3ccccc3)n2,4.06 | |
| CCN1CCC[C@H]1CNC(=O)c2cc(Br)cc(OC)c2OC,1.2 | |
| CC(O)c1ccc2OCC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,.25 | |
| CCN(CC)C(=O)c1ccc(cc1)C2=CC3(CCNCC3)Oc4cccc(O)c24,.54 | |
| CN(C)CC(O)COc1ccc(Nc2nccc(Nc3cccc(Cl)c3)n2)cc1,2.5 | |
| CC(=O)Nc1ccccc1C,1 | |
| Clc1ccc(OC2CCNCC2)cc1C(=O)NCC34CC5CC(CC(C5)C3)C4,1.83 | |
| COc1cccc(\C=C\2/SC(=O)NC2=O)c1N3CCC[C@@H](N)C3,1.27 | |
| COc1ccccc1CN2C(C(=O)NC3CCC(C)CC3)c4ccccc4C2=O,3.74 | |
| C[C@@H](Oc1cccc2ncnc(Nc3ccc4c(cnn4Cc5ccccn5)c3)c12)C(=O)N(C)C,2.89 | |
| COCCNC(=O)c1cccc(CN2NC(=O)C3=C(C2=O)C(=O)c4ccc(Cl)cc4N3)c1,1.2 | |
| Cc1ccc(cc1NC(=O)c2ccc(OCc3ccccn3)cc2)c4[nH]cnc4C,2.87 | |
| CCn1c2ccccc2c3cc(NC(=O)C)ccc13,3.5 | |
| CNc1c(Br)cnc2[nH]c(nc12)c3ccc(OCCN4CCCCC4)cc3,2.56 | |
| Cc1c(Sc2ccc(Cl)cc2)c3c(Cl)cccc3n1CC(=O)O,2.15 | |
| Oc1cccc(c1)c2nc3ccc(O)cc3s2,3.7 | |
| CN(C)C(=O)C1(CCN(CC[C@H](CN(C)C(=O)c2cc(cc3ccccc23)C#N)c4ccc(Cl)c(Cl)c4)CC1)N5CCCCC5=O,2.52 | |
| Cc1c(O[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)cccc1C(=O)N,1.6 | |
| [O-][N+](=O)c1oc(C=NN2CCOC2=O)cc1,-.12 | |
| Cc1ccc2c(c1)c(Sc3ccc(cc3)S(=O)(=O)C)c(C)n2CC(=O)O,-.08 | |
| Cc1ccc(cc1S(=O)(=O)n2ccc(n2)c3c(C)nc4ccc(Br)cn34)[N+](=O)[O-],3.52 | |
| OC1(CCc2ccc(Oc3ccc(cc3)C(=O)NCc4ccncn4)cc2)CN5CCC1CC5,.76 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c(SC(C)C)c(Cc3ccccc3C(F)(F)F)sc12,4.42 | |
| O=C1CC2(CCCC2)CC(=O)N1CCCCN3CCN(CC3)c4ncccn4,2.19 | |
| c1ccc2cnccc2c1,1.6 | |
| C[C@](N)(Cc1ccccc1)c2ccccc2,1.7 | |
| Clc1ccc2oc3C(=O)NC(=Nc3c2c1)[C@@H]4CCCN4,2.01 | |
| CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1CCCN(C1)S(=O)(=O)Cc2ccccc2)C(C)(C)C,.78 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4ccccn34)C(=O)N5CCOCC5,3.4 | |
| O=C(NCCN1CCCC1)c2ccc(Nc3ncc4cc(ccc4n3)c5ccncc5)cc2,2.39 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)c(F)c3)ncc2F,2.41 | |
| Cc1nc(C)c(nc1C(=O)N)c2ccc([C@@H]3CC[C@@H](CC(=O)O)CC3)c(Cl)c2,1.8 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(cc3)C(=O)N4CCCN(C)CC4)ncc2F,2.02 | |
| C[C@H](CO)Nc1nc(SCc2ccccc2)nc3nc(N)sc13,3.12 | |
| O=C(CCc1ccncc1)Nc2ccc(cc2)C(=O)c3ccccc3,3.4 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccncc3C#N)cn2)c4noc(n4)C(F)F,2.85 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccc(NC(=O)C(C)(C)C)cc3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,2.98 | |
| COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCCN4CCOCC4,3.4 | |
| Cc1c(Cl)ccc(OC2CCN(CC2)C3CCN(CC3)C(=O)c4cccc(c4)S(=O)(=O)C)c1Cl,3.33 | |
| CCCCc1nc2c(N)nc3ccccc3c2n1CC(C)C,3.82 | |
| CCN(CC)CCNC(=O)c1cc(Br)c(N)cc1OC,.54 | |
| OC(=O)Cc1ccc(cc1)c2ccc(NC(=O)c3oc(Nc4ccccc4F)nn3)cc2,1.5 | |
| O=S(=O)(N1CCCC1)c2ccccc2c3ccc(CNC4CCOCC4)cc3,1.4 | |
| Cc1ccc(NC(=O)C=C)cc1,2.25 | |
| COc1cc(F)ccc1c2cncc(CNC3CCCC3)c2,2.29 | |
| CC(Cc1ccc(O)cc1)NCC(O)c2cc(O)cc(O)c2,-.06 | |
| C[C@@H](Oc1cccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c12)C(=O)N(C)CCO,3.85 | |
| COc1cc(ccc1N)C(=O)NC[C@@H](O)CN2CCC(CC2)Oc3ccc(Cl)c(Cl)c3,3.12 | |
| CNc1c(Br)cnc2[nH]c(nc12)c3ccc(OCCN4CCN(C)CC4)cc3,2.91 | |
| COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4occc4,1.9 | |
| Cc1c(sc2ncnc(O)c12)C(=O)Nc3ccccc3,2.13 | |
| COCC(=O)N1CCC(CC1)n2cc(cn2)c3cnc(N)c(c3)c4oc5ccccc5n4,3.4 | |
| CCCC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc2ccc(OC)cc2)NC(=O)[C@@H](N)Cc3cncn3C)c4ccccc4,2.51 | |
| CCN(C1CCN(CC[C@H](N2CCN(CC2)S(=O)(=O)CC(F)(F)F)c3ccccc3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,1.8 | |
| CCN1C(=O)C=Cc2cc(COc3cc(F)cc(c3)C4(CCOCC4)OC)ccc12,3.89 | |
| CC(=O)OCCn1c(Sc2nc3cccc(Cl)c3s2)nc4c(N)ncnc14,3.16 | |
| CN1CCN(CC1)[C@@H]2C[C@@H](C2)c3nc(c4ccc5ccc(nc5c4)c6ccccc6)c7c(N)nccn37,3.2 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(C(=O)N)c(F)c3)n2,2.8 | |
| CCNC(=O)c1cc2c(c(cnc2[nH]1)c3cncc(c3)C4=NNC(=O)O4)n5ccc(n5)C(F)(F)F,1.65 | |
| CN(C)CCCN1c2ccccc2Sc3ccccc13,2.56 | |
| Cc1cc(Cl)ccc1OC2CCN(CC3CCN(CC3)[C@@H](Cc4ccc(F)cc4)C(=O)O)CC2,2.53 | |
| Nc1ncc(cc1c2oc3ccccc3n2)c4cnn(c4)C5CCN(CC5)C(=O)CO,3.2 | |
| CCc1cc(OCc2ccc(cc2)c3ccccc3c4nn[nH]n4)c5CCCCc5n1,1.7 | |
| C[C@@H]1CN(Cc2oc(nn2)c3cc(cc4[nH]ncc34)c5cccc6[nH]ccc56)C[C@H](C)O1,4.01 | |
| NC(=O)Nc1sc(cc1C(=O)N2CCOCC2)c3ccccc3,2.24 | |
| O=C(NCCCN1CCCCC1)C(c2ccccc2)c3ccccc3,1.33 | |
| Nc1c(Nc2ccccc2)nc(nc1N3CCOCC3)C#N,2.72 | |
| COc1cc(N2CCN(C)CC2)c3NC(=CC(=O)c3c1)C(=O)Nc4ccc(cc4)N5CCOCC5,2.7 | |
| O=C(NCc1occc1)c2ccc3[nH]c(COc4ccc(cc4)C56CC7CC(CC(C7)C5)C6)nc3c2,4 | |
| NC(=O)Nc1cc(sc1C(=O)N)c2ccccc2,2.43 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NS(=O)(=O)c3cccc(NC(=O)C)c3)C(=O)C(F)(F)F,2.43 | |
| CCN(c1ccccc1)c2cc(NC)[n+](C)c(C)n2,-.91 | |
| CCC(N(CCCN)C(=O)c1ccc(C)cc1)C2=Nc3ncccc3C(=O)N2Cc4ccccc4,-.04 | |
| Nc1ncnc2OCCN(C(=O)c12)c3ccc(cc3)[C@@H]4CC[C@@H](CC(=O)O)CC4,-.5 | |
| Cc1cnc(Oc2ccc(cc2)n3ccnc3)nc1Oc4ccc5OCOc5c4,3.56 | |
| Cc1csc(NC(=O)c2cc(Sc3nncn3C)ccc2N)n1,2.3 | |
| C[C@@](CCc1ccc(cc1)c2ccc(Cl)cc2)(C(=O)NO)S(=O)(=O)C,2.4 | |
| CN1CCN(CC(=O)N2c3ccccc3C(=O)Nc4cccnc24)CC1,-.49 | |
| O=C(NCC#N)[C@@H]1CCCC[C@H]1C(=O)N2CCN(CC2)c3ccc(cc3)C#N,1.79 | |
| Nc1ccc2nc(sc2c1)c3ccc(O)cc3,3.1 | |
| COCCC(Oc1ncnc2c1cnn2c3ccccc3C(F)(F)F)C(=O)Nc4ccc(C)cn4,3.5 | |
| CCN(C)C(=O)c1ccc(cc1)C(=C2CCN(Cc3cscn3)CC2)c4cccc5cccnc45,2.65 | |
| C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)nc(OC4CC5CC5C4)nc23,1.66 | |
| Cc1cccc(n1)c2nn3CCCc3c2c4ccnc5ccc(cc45)C(=O)N,1.71 | |
| CC1=C(Oc2c(cccc2C1=O)C(=O)OCCN3CCCCC3)c4ccccc4,3.42 | |
| CCC(CC)NC(=O)c1cnn(c1NS(=O)(=O)C2CCCC2)c3ccccc3,.69 | |
| CC[C@@H](CO)Nc1nc(SCc2ccccc2)nc3nc(N)sc13,2.99 | |
| Nc1nc(N)c2cc(Br)ccc2n1,1.78 | |
| CCC(=C)C(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl,.02 | |
| Oc1c2C(=O)N(NC(=O)c2nc3cc(Cl)ccc13)C(c4ccccc4)c5ccncc5,1.1 | |
| CSc1ccc2Sc3ccccc3N(CCC4CCCCN4C)c2c1,3.76 | |
| C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)nc(OC4CCOC4)nc23,-.06 | |
| COc1cc(Nc2cc(Nc3c(Cl)ccc4OCOc34)ncn2)cc(OC)c1OC,3.07 | |
| CC1=CN(C2CCCN(Cc3cccc(Oc4ccc(Cl)cc4)c3)C2)C(=O)NC1=O,3.38 | |
| CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]2O[C@H](C)[C@@H](O)[C@H]2O,.67 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(cc3)N4CC[C@H](C4)NC(=O)C)ncc2F,3.3 | |
| CC[C@@H](N1CCC[C@@H](C1)N2C=C(C)C(=O)NC2=O)c3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3,.22 | |
| COc1ccc(cc1OC)c2csc(NC(=O)c3c(C)onc3C)n2,3.16 | |
| CS(=O)(=O)Cc1cc(nc(n1)c2ccccc2)N3CCOCC3,1.94 | |
| CN([C@@H]1CCN(Cc2nc3cc(F)ccc3s2)C[C@@H]1F)C(=O)Cc4ccc(cc4)S(=O)(=O)C,2.2 | |
| CC(C)N1CCN[C@@H](CN2CCN(CC2)C(=O)Nc3ccc(Cl)c(Cl)c3)C1,1.92 | |
| Cn1cnc(c2ccccc2)c1c3nc4c(N)ncnc4s3,2.69 | |
| CCCN(CCO)CCCOc1cc2ncnc(Nc3cc(CC(=O)Nc4cccc(F)c4F)[nH]n3)c2cc1OC,1.28 | |
| CC(C)C[C@H](N[C@@H](c1ccc(cc1)c2ccc(cc2)S(=O)(=O)C)C(F)(F)F)C(=O)NCC#N,3.24 | |
| CN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)N,2.3 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccc(cc3)S(=O)(=O)C)cn2)C(=O)OC(C)(C)C,3.6 | |
| CC1=CC2=NNC(=O)N2c3cc(ccc13)c4cn[nH]c4,2.13 | |
| CNc1cccc(CCOc2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)n1,-.15 | |
| CCC(N(CCCN)C(=O)c1ccc(C)cc1)C2=Nc3nccnc3C(=O)N2Cc4ccccc4,-.14 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CN=C1c2cccnc2)NC(=O)OCc3ccccc3)C(=O)C(F)(F)F,2.15 | |
| OC(=O)CCn1c2ccccc2c3ccccc13,.6 | |
| CSc1ncccc1C(=O)NCCc2ccc(Cl)cc2,3.31 | |
| COc1nc(Cl)cnc1NS(=O)(=O)c2cccc3c(cccc23)N(C)C,1.74 | |
| O[C@@H](CNCCc1cccc(CNCCCc2ccccc2)c1)c3ccc(O)c4NC(=O)Sc34,1.11 | |
| CCCN(CCCOCCOCCc1ccccc1)CCc2ccc(O)c3nc(O)sc23,2.74 | |
| C[C@H](CO)Nc1nc(SCc2cccc(Cl)c2F)nc3NC(=O)Sc13,3.53 | |
| C1CC(CCN1)c2ccccc2,.54 | |
| Nc1cccc(NS(=O)(=O)c2ccc(cc2)c3ccc(cc3)C#N)n1,2.2 | |
| CS(=O)(=O)c1ccc(CC(=O)N(CC=C)C2CCN(CCC(c3ccccc3)c4ccccc4)CC2)cc1,3.1 | |
| COc1cc2c(Nc3c(Cl)ccc4OCOc34)ncnc2cc1OCCCN5CCCC5,1.62 | |
| CN(C)CCOc1ccccc1Cc2ccccc2,2.53 | |
| Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1,-1.33 | |
| Cc1c[nH]c(n1)c2cnc(NCCNc3ccc(cn3)C#N)nc2c4ccc(Cl)cc4Cl,3.86 | |
| Cc1ccc(cc1NC(=O)c2ccc(OCc3ccccn3)cc2)c4c[nH]cn4,2.81 | |
| ONC(=O)[C@@H](Cc1ccc2ccccc2c1)NS(=O)(=O)c3ccc4ccccc4c3,3.23 | |
| COc1cc(\C=C/2\SC(=O)NC2=O)cc(OC)c1O,.74 | |
| NC(=O)c1sc(cc1N)c2ccsc2,2.23 | |
| CC(C)CNc1nc(nc(N2CCOCC2)c1N)C#N,2.79 | |
| CC1=CC2=NNC(=O)N2c3cc(ccc13)c4ccc(CO)cc4,2.86 | |
| Fc1ccc(cc1F)S(=O)(=O)NCC(N2CCCCCC2)c3ccccc3,2.84 | |
| CCc1cc(O)c(Oc2ccc(cc2F)C(=O)N)cc1F,2.87 | |
| Clc1ccc(OC2CCN(CC2)C3CCN(CC3)S(=O)(=O)NC(=O)c4ccccc4)cc1Cl,2.14 | |
| OC(=O)c1cc2cc(ccc2n1Cc3ccc(Cl)c(Cl)c3)C(F)(F)F,3.07 | |
| C[C@H](CO)N1C=Cc2c(NC(=O)Cc3ccc(Cl)c(c3)C(F)(F)F)cccc2C1=O,3.49 | |
| COc1ccc2COC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,.5 | |
| Nc1ncnc2ccccc12,1.26 | |
| CCNC(=O)c1cc2c(c(cnc2[nH]1)c3cc(cnc3OC)C4=NNC(=O)O4)n5ccc(n5)C(F)(F)F,2.91 | |
| C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc3[nH]c(N)nc13,3.22 | |
| CCN(CC)CCn1c2ccccc2c3cnc(N)c(C#N)c13,2.7 | |
| CN1[C@@H]2CC[C@H]1C[C@H](C2)OC(=O)C(O)c3ccccc3,-1.29 | |
| C[C@H](N)COc1c(C)cccc1C,.6 | |
| CC(C(=O)O)c1ccc2oc(nc2c1)c3ccc(Cl)cc3,1.3 | |
| Cn1c(CN2CCC(CC2)c3ccccc3)nc4ccccc14,3.6 | |
| COc1cccc(c1OC)c2ccc(\C=C\3/SC(=S)N([C@@H](Cc4ccccc4)C(=O)O)C3=O)cn2,1.5 | |
| Cc1cnc([nH]1)c2cc(NC(=O)c3ccc(nc3C)C(F)(F)F)ccc2Cl,3.3 | |
| Nc1cccc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1Cl,3.29 | |
| Nc1c(nc(nc1N2CCOCC2)C#N)N3CCCC3,2.25 | |
| COCCNCc1cncc(n1)c2ccc(F)cc2OC,1.61 | |
| CCN1CCN(Cc2cnc(c3ccc(cc3)C(=O)Nc4ccccc4N)c(c2)C#N)CC1,1.14 | |
| CSc1nc(N)nc(n1)c2ccccc2,2.98 | |
| O=C1N=C2C(=C1C#N)c3ccc(N4CCSCC4)c5cccc2c35,3.22 | |
| CC1=C(C(=O)c2ccc(O)cc2O1)c3ccccc3,2.95 | |
| COc1ccc(OC)c(c1)c2c(F)ccc3c(N)c(nnc23)C(=O)NC(C)C,3.77 | |
| Oc1c2ncc3ccccc3c2nn1c4ccc(Cl)cc4,1.52 | |
| CC(NC(=O)C)c1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,3.1 | |
| CCN(C1CCN(CC[C@@H](c2ccc(F)cc2)c3ccc(cc3)S(=O)(=O)C)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,1.88 | |
| O=C(Nc1ccc(nc1)N2CCOCC2)c3oc(Nc4ccccc4)nn3,2.9 | |
| CC1(C)CNC(=O)c2sc(nc2C1)N3CCOCC3,1.29 | |
| C[C@]12CC[C@H]3[C@@H](CC(=C)C4=CC(=O)C=C[C@]34C)[C@@H]1CCC2=O,2.98 | |
| Clc1ccc2OCOc2c1Nc3ccnc(Nc4cc(cc(c4)N5CCOCC5)N6CCOCC6)n3,3.25 | |
| CC(C)Cn1cnc(c2ccccc2)c1c3nc4c(N)ncnc4s3,3.72 | |
| NC(=O)Nc1sc(cc1C(=O)N[C@H]2CCCNC2)c3ccccc3,1.27 | |
| CCN(CC)C(=O)c1ccc(cc1)C(=C2CCNCC2)c3ccccc3OC,1 | |
| COc1c(C)cnc(Cn2cnc3c(Cl)nc(N)nc23)c1C,1.67 | |
| CC(C)(C(=O)N)C(=O)NCCCNc1nc(Nc2cccc(NC(=O)N3CCCC3)c2)ncc1Br,2.32 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N(C)[C@H]2CCCN(CCc3ccccc3)C2,2.34 | |
| CC1=CC2=NNC(=O)N2c3cc(ccc13)c4ccncc4,2.29 | |
| COc1cc2CC[C@H](NC(=O)C)c3cc(O)ccc3c2c(OC)c1OC,1.81 | |
| Nc1ncc(NC(=O)c2cc(NC(=O)c3cccc(c3)C(F)(F)F)ccc2Cl)cc1Cl,3.26 | |
| CCCCNc1ccc(cc1)C(=O)OCCN(C)C,2.11 | |
| CC(Oc1c(Cl)cccc1Cl)C2=NCCN2,.48 | |
| C[C@H](NC(=O)c1c(C)nn(c1NS(=O)(=O)c2cccnc2)c3ccc(F)cc3)C(C)(C)C,.4 | |
| Cc1c(Oc2ccc(Cl)cc2)c3c(NS(=O)(=O)C)cccc3n1CC(=O)O,-.98 | |
| c1ccc(nc1)c2n[nH]c(n2)c3ccncc3,1.48 | |
| CCC(N(CCCN)C(=O)c1ccc(C)cc1)C2=Nc3ccsc3C(=O)N2Cc4ccccc4,1.81 | |
| C[C@H](COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C)OC(=O)[C@H](C)N,3.19 | |
| Fc1ccc(CN2CCN(CC2)c3ccc4nnc(n4n3)C(F)(F)F)cc1,3.46 | |
| Oc1c2C(=O)NNC(=O)c2nc3cc(Cl)cc(Cl)c13,.89 | |
| CCN(CC)C(=O)c1ccc(cc1)C(=C2CCNCC2)c3cccc(c3)C(F)(F)F,1.9 | |
| CC[C@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(Cl)s1,2.7 | |
| COCCCOc1ccnc(C[S+]([O-])c2nc3ccccc3[nH]2)c1C,-.69 | |
| NS(=O)(=O)c1ccc2C(=CNC(=O)c2c1)C(=O)NC[C@@H](O)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,2.17 | |
| O=C1OC(=Cc2ccccc12)c3ccccc3,3.84 | |
| CC(C)[C@@H]1N(C)c2ccccc2C[C@@H](CO)NC1=O,2.03 | |
| CC(=O)NCc1ccc(CN2CCN(CC2)c3ccccc3)cc1,1.78 | |
| COc1ccc(CN2C(=O)NC3=C(C=C(N(CC(=O)NC(C(C)C)C(=O)C(F)(F)F)C3=O)c4ccccc4)C2=O)cc1,2.93 | |
| COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN(C)C,2.9 | |
| CCOC(=O)c1ccc(COC2CN(C2)c3ccc(C)nn3)cc1,2.5 | |
| CC1=CC(=O)Oc2c(C)c3oc(C)cc3cc12,3.47 | |
| CC(C)N1CCC[C@@H](CN2CCN(CC2)C(=O)Nc3ccc(Cl)c(Cl)c3)C1,1.62 | |
| CCOc1cc(CC(=O)N[C@@H](CC(C)C)c2ccccc2N3CCCCC3)ccc1C(=O)O,2.31 | |
| CS(=O)(=O)N1CCC(CC1)NC(=O)NC23CC4CC(CC(C4)C2)C3,2.7 | |
| Oc1ncnc2onc(c3ccc(F)cc3)c12,1.97 | |
| Cc1c(Sc2ccc(Cl)cc2)c3c(cccc3n1CC(=O)O)S(=O)(=O)C,.58 | |
| NC1(CCN(CC1)c2ncnc3[nH]ccc23)C(=O)NC(CCO)c4ccc(Cl)cc4,2.5 | |
| OC(=O)c1ccc2[nH]c(nc2c1)C(F)(F)F,-1.08 | |
| CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13,3.37 | |
| C[C@H]1NC(C)(C)CO[C@]1(O)c2cccc(Cl)c2,1.69 | |
| CS(=O)(=O)C1(CC1)c2cc(nc(n2)c3cccc4[nH]ccc34)N5CCOCC5,2.2 | |
| Cc1nc(C)c(nc1C(=O)N)c2ccc(cc2)[C@@H]3CC[C@@H](Cc4nnn[nH]4)CC3,1.4 | |
| COc1cc2c(Nc3ccc(F)cc3F)c(cnc2cc1NCCN(C)C)C(=O)N,1.71 | |
| COc1cccc(Nc2c(cnc3c(C)cc(cc23)S(=O)(=O)c4cccc(c4)C(=O)N(C)C)C(=O)N)c1,2.69 | |
| O=C1C=C(N=C2N1C=Cc3ccccc23)N4CCOCC4,2.78 | |
| O=S(=O)(N1CCOCC1)c2cccc(c2)c3cn4cccnc4n3,1.3 | |
| CC(C)Oc1cc(ccc1NC(=O)CN2CCOCC2)c3cccc4C(=O)C=C(Oc34)N5CCOCC5,3 | |
| COc1ccnc(NC2CCN(CC2)C(=O)c3ccc(Cl)cc3)c1,2.82 | |
| CN1CCN(CC1)C(=O)c2cccc(CC3=NNC(=O)c4ccccc34)c2,.92 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2CCCCN(Cc3ccccc3)C2,2.12 | |
| Clc1ccc(cc1)C(N2CCNCC2)c3ccccc3,1.94 | |
| CC(=O)N1CCOc2nc(OCc3ccccc3)ccc12,2.4 | |
| CN1CCN(CC1)c2ccc3N=CN(C(=O)c3c2)c4cc(ccc4C)C(=O)NC5CCC5,2.25 | |
| NC1(CCC1)c2ccc(cc2)c3nc4ccccn4c3c5ccccc5,2.8 | |
| CC(C)(C)NC(=O)C(N(Cc1occc1)C(=O)c2ccc([nH]2)c3ccccc3)c4ccncc4,4.13 | |
| Cc1cc(Nc2nc(NCc3ccccn3)ncc2Br)n[nH]1,2.8 | |
| CC(C)CC1(CC=C)C(=O)NC(=O)NC1=O,1.48 | |
| CCOC(=O)C1=COc2ccccc2C1=O,1.81 | |
| CN(C(=O)C)c1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4)cc1,2.88 | |
| CC1CCCCC1NC(=O)c2c(C)nn(c2NS(=O)(=O)c3ccc(C)cc3)c4ccccc4,1.94 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3ccnc4ccc(F)cc34)c2C(=O)N5CC[C@@H](O)C5,1.95 | |
| COc1ccccc1CNCc2ccc(CCNC[C@H](O)c3ccc(O)c4NC(=O)Sc34)cc2,.15 | |
| C[C@@](O)(C(=O)Nc1ccc(cc1Cl)S(=O)(=O)NCCCO)C(F)(F)F,2.1 | |
| CN1c2ccccc2C(NCCCCCCC(=O)O)c3ccc(Cl)cc3S1(=O)=O,1.33 | |
| COc1ccc(\C=C\2/SC(=S)NC2=O)cc1OC,1.42 | |
| CS(=O)(=O)c1ccc2[nH]c3CCN(Cc3c2c1)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,1.5 | |
| COc1cc2ncc(C(=O)N)c(Nc3cc(F)ccc3F)c2cc1OC,2.9 | |
| Cc1cc(C)cc(c1)c2oc(SCC(=O)N3CCN(CC3)C(=O)c4occc4)nn2,3 | |
| COc1cc(ccc1Nc2ncc(OC)c(n2)c3cnc4ccccn34)N5CCN(CC5)C(=O)C,3.2 | |
| OC(=O)[C@H](Cc1ccc(OCCc2ccc3CCCNc3n2)cc1)NC(=O)c4c(Cl)cccc4Cl,.33 | |
| COc1cc(CCc2cc(Nc3ccnc(NCc4onc(C)c4)n3)n[nH]2)cc(OC)c1,3.1 | |
| CS(=O)(=O)Cc1cc(nc(n1)c2ccc(NS(=O)(=O)C)cc2)N3CCOCC3,.85 | |
| COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1,2.27 | |
| NS(=O)(=O)c1cc(cc(N2CCCC2)c1Oc3ccccc3)C(=O)O,-.94 | |
| Cc1nccn1CCC(C(=O)N)(c2ccccc2)c3ccccc3,1.79 | |
| CC(C(=O)O)c1cccc(Oc2ccccc2)c1,.71 | |
| CNC(=O)c1cccc2c1c(Sc3ccc(Cl)cc3)c(C)n2CC(=O)O,-.89 | |
| O=C1C=C(Oc2c1cccc2c3cccc4c5CCCCc5sc34)N6CCOCC6,4.1 | |
| CN1CCCC1CCNC(=O)c2ccc(Nc3ncc4cc(ccc4n3)c5ccncc5)cc2,2.01 | |
| CC(=O)c1noc(C)c1C(=O)Nc2nccs2,1.94 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4c(N)cccn34)N5CCN(CC5)C(=O)C,3.4 | |
| O=C(N[C@@H]1CN2CCC1CC2)c3ccc(s3)c4ccccc4,1.77 | |
| Cc1c(c2ccc(O)cc2)n(C)c3ccc(O)cc13,3.8 | |
| CNC(=O)c1ccc(Nc2ncc(F)c(n2)c3cnc(C)n3C(C)C)cc1,3 | |
| COC(=O)C1=C(C)NC(=C([C@@H]1c2cccc3nonc23)C(=O)OC(C)C)C,3.77 | |
| COc1cc(F)ccc1c2cncc(CNC(=O)C3CCC3)c2,3.2 | |
| Oc1cc(Cl)cc(Cl)c1,3.58 | |
| CSc1ccc(cc1)c2nc(c3ccc(F)cc3)c([nH]2)c4ccncc4,2.97 | |
| COc1c(N2C[C@@H]3CCCN[C@@H]3C2)c(F)cc4C(=O)C(=CN(C5CC5)c14)C(=O)O,-.18 | |
| CCOc1cc2nnc(C(=O)N)c(Nc3ccc(F)cc3F)c2cc1N4CCN(C)CC4,2.63 | |
| CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(Cc3ccncc3)cc2,2.8 | |
| NC(=O)c1cccc(OC2CCN(Cc3ccccc3)CC2)c1,1.92 | |
| C[C@H](Nc1nc(Nc2cc(C)[nH]n2)c(Cl)c(n1)N3CCOCC3)c4ncc(F)cn4,2.61 | |
| CN(C(=O)C)c1ccccc1,1.1 | |
| CN(C)C(=O)c1ccc(CN2CCC(CC2)c3ccc(cc3)C(=O)Nc4ccccc4N)cc1,1.53 | |
| COC1=CC=C2C(=CC1=O)[C@H](CCc3cc(OC)c(OC)c(OC)c23)NC(=O)C,.82 | |
| CC(C)(C)c1ccc(cc1)c2n[nH]c(NC(=O)c3ccccc3Cl)c2Br,4.3 | |
| CC(C)[C@@H]1N=C(c2ccccc2)c3ccccc3NC1=O,3.05 | |
| OC(=O)COc1cccc(c1)C(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,1.09 | |
| O=C1COc2ccccc2N1CCN3CCC(CC3)NCc4cc5OCCOc5cn4,1.04 | |
| CNCCC=C1c2ccccc2CCc3ccccc13,1.58 | |
| CN1CCCC(CC1)N2N=C(Cc3ccc(Cl)cc3)c4ccccc4C2=O,2.46 | |
| O=C(Nc1ccccc1)N2CCOCC2,1 | |
| CCn1c2ccccc2c3cc(NC(=O)N4CCOCC4)ccc13,3.2 | |
| Cc1ccc(NC(=O)c2cccc(c2)N3CCOCC3)cc1NC(=O)c4ccc(OCc5ccncc5)cc4,3.2 | |
| CN(C)CC(O)COc1ccc(Nc2nccc(Nc3cc(C)ccc3Cl)n2)cc1,2.6 | |
| CC(=O)Nc1cccc(OCc2cnc(Cl)s2)c1,2.38 | |
| OCC(=O)N1CCC[C@H]1COc2cccc3ncnc(Nc4ccc(OCc5ccccn5)c(Cl)c4)c23,3.62 | |
| COc1ccc(cc1)c2nc(nc(O)c2C#N)N3CCOCC3,.2 | |
| CN1CCC(COc2cc(OC3CCOCC3)c4c(Nc5c(Cl)ccc6OCOc56)ncnc4c2)CC1,2.59 | |
| COc1cc2ncnc(NCc3ccccc3)c2cc1OC,3.29 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3ccccc3C(F)(F)F)c2C(=O)N4CC=CC4,3.53 | |
| CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc3ccc(OC)cc13,2.17 | |
| Cc1ccc(Oc2ccc(OCC(=O)Nc3ccncc3)cc2)cc1,4.3 | |
| Cn1cnc2cc(OC(=O)c3ccccc3)cnc12,2.4 | |
| Brc1cc(Br)cc(COC[C@@H](N2CCNCC2)c3ccccc3)c1,2.8 | |
| Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CCCCCC2,.01 | |
| Oc1ccc(cc1)C2CC(=O)c3c(O)cc(O)cc3O2,2.6 | |
| Nc1c(c(CN2CCOCC2)nn1c3ccc(F)cc3)c4ccccc4,2.33 | |
| C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc3NC(=O)C(=Cc13)C#N,3.32 | |
| Nc1nc2ccc(Cl)cc2c3nc(nn13)c4occc4,3.98 | |
| COc1ccc2ncc(F)c(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2n1,1.78 | |
| CCN(CC)CCN1C(=O)CN=C(c2ccccc2F)c3cc(Cl)ccc13,2.38 | |
| NC1(CCC1)c2ccc(cc2)c3ncc4ccccc4c3c5ccccc5,3.6 | |
| CS(=O)(=O)c1ccc(cc1Cl)[C@@H](CC2CCCC2)C(=O)Nc3cnc(cn3)[C@H](O)CO,2.58 | |
| CCN(C(=O)C)c1cccc2c1c(Sc3ccc(Cl)cc3)c(C)n2CC(=O)O,1.61 | |
| COc1ccc(COC(=O)N2CCC(CNc3ncccn3)CC2)cc1,3.14 | |
| CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)O)[C@@H]12,-.76 | |
| O[C@H](CNC(=O)c1cccc(c1)C#N)CN2CCC(CC2)Oc3ccc(Cl)c(Cl)c3,3.48 | |
| CN(C)C(=O)Nc1ccc(CN2NC(=O)C3=C(C2=O)C(=O)c4ccc(Cl)cc4N3)cc1,1.1 | |
| COc1cc(Nc2cc(Oc3cccnc3C)ccn2)cc(OC)c1OC,3.19 | |
| CCOc1ccccc1c2ccc3c(c2)C(=O)C(=O)c4ccccc34,2.67 | |
| Cc1cccc(NC(=O)NCC(N2CCOCC2)c3cccnc3)c1,2 | |
| Fc1ccc2c3CN(CCc3[nH]c2c1)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,2.99 | |
| CNC1=Nc2ncccc2C(=NC1c3cccs3)c4ccns4,2.15 | |
| CCC(N(CCCN)C(=O)c1ccc(C)nc1)C2=Nc3ccsc3C(=O)N2Cc4ccccc4,2.56 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccc(cc3F)S(=O)(=O)C)cn2)C(=O)OC(C)(C)C,3.7 | |
| CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1,3.92 | |
| NC1(CCN(CC1)c2ncnc3[nH]ccc23)C(=O)NC(c4ccccc4)c5ccc(Cl)cc5,4.1 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C(=O)N[C@@H](C(c3ccccc3)c4ccccc4)C(=O)OC,2.42 | |
| O=C1C=C(Nc2cc(Cc3ccccc3)ccc12)c4cccnc4,3.46 | |
| COc1cc(O)ccc1\C=C\2/CCCN=C2c3cccnc3,2.2 | |
| CCCNC(=O)c1nnc2c(cccc2c1N)c3ccccc3,3.8 | |
| COc1cc(ccc1Cn2ncc3ccc(NC(=O)CC4CCCC4)cc23)C(=O)NS(=O)(=O)c5ccccc5,1.6 | |
| COc1cc2c(ncnc2cc1OCCCN3CCCCC3)N4CCN(CC4)C(=O)Nc5ccc(OC(C)C)cc5,2.6 | |
| CC1=CC(=O)Nc2sc(C(=O)c3ccc(Br)cc3)c(N)c12,2.57 | |
| COC(=O)CCCCCCC(=O)Nc1ccc2c(c1)C(=O)C(=O)c3ccccc23,2.9 | |
| Cc1cc(Cl)ccc1OC2CCN(C[C@H](O)CNC(=O)C3=CNC(=O)C=C3C(F)(F)F)CC2,2.37 | |
| CCCSc1c(cnn1C)C(=O)NC2CCCCC2,2.99 | |
| CS(=O)(=O)c1ccc(cc1)c2cc(ccc2OCC(=O)O)C(F)(F)F,-.87 | |
| O=C(OCCN1CCCCC1)c2c[nH]c3ccccc23,2 | |
| CO[C@H]1CN(CCCOc2ccc(F)cc2)CC[C@H]1NC(=O)c3cc(Cl)c(N)cc3OC,3.56 | |
| CN(C)CC(C)(C)COc1nccc(Nc2cc(NC(=O)c3ccnc(c3)N4CCOCC4)ccc2C)n1,2.2 | |
| CCc1cc2C(=NCc3nnc(C)n3c2s1)c4ccccc4Cl,2.52 | |
| OC(=O)COc1ccc(cc1c2ccccc2)C#N,-1.08 | |
| CS(=O)(=O)Cc1cc(nc(n1)c2ccc3[nH]ccc3c2)N4CCOCC4,2.06 | |
| FC(F)(F)c1nn(cc1C(=O)NCCNC(=O)c2ccc(Cl)cn2)c3ccccc3,3.8 | |
| CNC(=O)c1cccc(NC(=O)Nc2cccc(c2)C#N)c1CN3CCC(Cc4ccc(F)cc4)CC3,3.97 | |
| NC1(CCN(CC1)c2ncnc3[nH]ccc23)C(=O)NC(Cc4ccccc4)c5ccc(Cl)cc5,4.1 | |
| Cc1oc(cc1C(=O)O)c2ccc(Cl)cc2,1.67 | |
| CSc1nc2cc(Cl)ccc2[nH]1,3.22 | |
| CC(C)C[C@H](CO)Nc1nc(SCc2cccc(c2)C#N)nc3nc(N)sc13,3.9 | |
| OC(=O)C[C@@H]1CC[C@H](CC1)c2ccc(cc2)c3ccc(Nc4ccc(nc4)C(F)(F)F)cn3,3.8 | |
| COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC,.63 | |
| CN(C)C(=O)N[C@@H]1CC[C@@H](CN2[C@@H]3CC[C@H]2C[C@H](C3)Oc4cccc(c4)C(=O)N)CC1,-.07 | |
| O[C@@H](CNCCc1cccc(CNCCc2ccccc2F)c1)c3ccc(O)c4NC(=O)Sc34,1.06 | |
| Cc1ccc(CNC(=O)C2CCCN2S(=O)(=O)c3ccc(F)cc3)cc1,2.9 | |
| CC(NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4ccc(cc4)S(=O)(=O)C,1 | |
| OC(=O)COCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3,1.27 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccncc3C#N)cn2)C(=O)OC(C)(C)C#N,2.3 | |
| CN(C1CCN(Cc2ccc(cc2)C(F)(F)F)CC1)C(=O)Cc3ccc(c(F)c3)S(=O)(=O)C,3 | |
| CCOc1cccc2c3CN(CCc3[nH]c12)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,3.1 | |
| Oc1cc(nc2ncnn12)c3ccccc3,-.21 | |
| NC(=O)c1nnn(c1N)c2ccccc2,.74 | |
| OC(c1ccccc1)c2cccnc2,1.72 | |
| CN1CCN(CC1)c2ccc3N=CN(C(=O)c3c2)c4cc(ccc4C)C(=O)Nc5nccs5,2.56 | |
| CN1C(=O)N(CC2CC2)c3nn(Cc4cn(C)c5ccc(Cl)cc45)c(c6cc(oc6C)S(=O)(=O)C)c3C1=O,4.48 | |
| CC(CN1c2ccccc2Sc3ccccc13)N(C)C,2.67 | |
| CCc1nc2c(N)nc3ccccc3c2n1Cc4ccccc4,3.29 | |
| NCC[C@@H](Oc1ccc(Cl)cc1C#N)c2ccccc2,.91 | |
| CCn1c(nc2c(ncc(OCC3CCCNC3)c12)C#CC(C)(C)O)c4nonc4N,.6 | |
| Cc1cc(Oc2ccnc(Nc3cccc(c3)N4CCOCC4)c2)c(nc1C)c5ccccn5,3.27 | |
| Cc1c(Cl)c(ccc1OC2CCN(CC3CCN(CC3)[C@@H](Cc4ccc(F)cc4)C(=O)O)CC2)C#N,2.19 | |
| c1ccc2[nH]c(nc2c1)c3cscn3,2.35 | |
| CCN(C1CCN(CC[C@H](C2CCN(CC2)S(=O)(=O)C)c3cc(Cl)cc(Cl)c3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,2.6 | |
| C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc3nc(C)cnc13,3.55 | |
| COc1ccc2Sc3ccccc3N(C[C@H](C)CN(C)C)c2c1,2.99 | |
| Oc1nc(nc2ccccc12)c3ccccc3,2.46 | |
| CN1C(=O)N(CC2CC2)c3nn(Cc4ccnc5ccc(Cl)cc45)c(c6cc(oc6C)S(=O)(=O)C)c3C1=O,3.2 | |
| COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCN(C)C,3.26 | |
| NC(=N)Nc1ccc(cc1)C(=O)Oc2ccc(Cl)cc2,.7 | |
| C[C@@](O)(C(=O)Nc1ccc(cc1Cl)C(=O)N2CCCCC2)C(F)(F)F,2.62 | |
| CC1(CC(=O)NC(=N1)N)c2ccc(Cl)c(Cl)c2,1.59 | |
| CC(C)[C@H](NC(=O)C[C@H](NC(=O)\C=C\c1ccccc1)c2ccccc2)C(=O)[C@H]3[C@H](C)C(=O)NC3=O,1.91 | |
| O=C1O[C@]2(CN3CCC2CC3)CN1c4cccs4,.9 | |
| CCN(CCO)CCCOc1cc2ncnc(Nc3cc(CC(=O)Nc4cccc(F)c4F)[nH]n3)c2cc1OC,1.94 | |
| OC[C@H](O)CN1C(=O)[C@H](Cc2ccccc12)NC(=O)c3cc4cc(Cl)sc4[nH]3,3.3 | |
| CC(O)C(C)OC(=O)[C@@H]1CC2C(Cc3cn(C(C)C)c4cccc2c34)N(C)C1,2.8 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4ccccn34)N5CC6COCC(C5)N6,3 | |
| COc1ccnc(NC2CCN(CC2)C(=O)c3ccc(cc3)C#N)c1,1.73 | |
| Cc1c(Cl)c(Cl)ccc1OC2CCN(CC3CCN(CC3)[C@@](C)(Cc4ccc(F)cc4)C(=O)O)CC2,2.98 | |
| O=C(Nc1ccc(nc1)N2CCOCC2)c3oc(Nc4cccc(OCc5ccccn5)c4)nn3,3.1 | |
| CC(O)(C(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccccc2)C(F)(F)F,3.07 | |
| CNc1nc2nc(SCc3cccc(F)c3F)nc(N[C@H](C)CO)c2s1,3.7 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c(SCCCO)n(Cc3cccc4ccccc34)cc12,4.36 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CC=C1c2ccccc2)NC(=O)CN3C(=O)CCC3=O)C(=O)C(F)(F)F,.96 | |
| CN1CCC(CC1)NC(=O)c2ccc(Oc3ccc(cc3)C#C[C@]4(O)CN5CCC4CC5)cc2,1 | |
| CN1CCN(CC1)c2ccc3ncc(C(=O)N)c(Nc4ccc(Cl)cc4Cl)c3c2,3.23 | |
| COc1ccc(CNCc2cccc(CCNC[C@H](O)c3ccc(O)c4NC(=O)Sc34)c2)cc1,.86 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2CCCN(CCc3ccc(F)cc3)C2,2.39 | |
| COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCC4CCNCC4,1.1 | |
| Nc1nc2cc3CCN(Cc4cnc[nH]4)CCc3cc2s1,-.12 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccc(NC(=O)Cc4ccccc4)cc3)CC1)C(=O)Cc5ccc(cc5)S(=O)(=O)C,3.61 | |
| FC(F)(F)CCS(=O)(=O)Oc1ccc(NC(=O)c2ccc(Cn3ccnn3)c4ccccc24)c(n1)C(=O)NCC5CCOCC5,4.2 | |
| CC(CC(=O)NCc1ccccc1)C2CCCO2,2.1 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2CCN(CCCc3ccccc3)C2,1.9 | |
| CNc1cc(nc2c(cc(OC)cc12)N3CCN(C)CC3)C(=O)Nc4ccc(cc4)N5CCOCC5,2.93 | |
| CS(=O)(=O)Cc1ccc2ccn(c3cc(NC4CC4)n5ncc(C#N)c5n3)c2c1,2.49 | |
| CCn1c2ccccc2c3cc(NC(=O)CN(C)C)ccc13,3.2 | |
| OC(=O)COc1ccc(Cl)cc1C2CCCCC2,.93 | |
| Oc1ccc2[nH]c(CN3CCC(Cc4ccc(F)cc4)CC3)nc2c1,3.8 | |
| Fc1ccc(CC2=NNC(=O)c3ccccc23)cc1C(=O)N4CCCNCC4,.1 | |
| Cn1cc(cc1c2c3C(=O)N(CC#N)C(=O)N(CC4CC4)c3nn2Cc5ccnc6ccc(Cl)cc56)C#N,3.33 | |
| Clc1ccccc1NC(=O)c2cc[nH]n2,2.58 | |
| CN(C)S(=O)(=O)c1ccc(CC(=O)N(C)C2CCN(CCC(c3ccccc3)c4ccccc4)CC2)cc1,3.5 | |
| C[C@@H](NC1=CC(=O)CCC1)c2ccc(Nc3ncc4cc(ccc4n3)c5ccncc5)cc2,3.17 | |
| O=C1C=C(Nc2ccccc12)c3occc3,2.21 | |
| Nc1nc2cc3CCN(Cc4ccccc4)CCc3cc2s1,2.66 | |
| Cc1onc(C)c1CCC2CCN(CC2)S(=O)(=O)CC3(CCC(F)(F)CC3)N(O)C=O,2.1 | |
| Oc1ccc(CCNCCCNS(=O)(=O)CCOCc2cccc3ccccc23)c4sc(O)nc14,1.69 | |
| c1ccc(cc1)c2ccc3ccccc3n2,4 | |
| O=C(NCC#N)[C@@H]1CCCC[C@H]1C(=O)N2CCC=CC2,.9 | |
| CNS(=O)(=O)NC1=CC=C(N(CC(=O)NC(C(C)C)C(=O)C(F)(F)F)C1=O)c2ccccc2,1.79 | |
| O=S(=O)(NCCNc1ncccn1)c2cccc3cnccc23,.61 | |
| COc1ccc2nc(C)cc(c2c1)n3cc(CNC(=O)C)nn3,1.6 | |
| Oc1ccc(CCNCCN(C2CCCCC2)C(=O)CCNCCc3ccc(Cl)c(Cl)c3)c4OCC(=O)Nc14,2.23 | |
| CCCCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O,2.37 | |
| C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc3nc(N)sc13,3.29 | |
| CCCS(=O)(=O)c1ccc(cc1)C(CNS(=O)(=O)c2ccc(cc2)C(F)(F)F)N3CCCCCC3,3.32 | |
| NC(=N)c1cc2c(\C=C\c3ccc4OCOc4c3)cccc2s1,2.2 | |
| OC(=O)C(N1CCCC(CN2CCC(CC2)Oc3ccc(Cl)c(Cl)c3)C1)c4ccccc4,2.6 | |
| CCOC(=O)c1cc(O)c(nn1)c2ccccc2,.69 | |
| c1ccc2c(c1)nnn2c3ccncc3,1.69 | |
| Cc1cccc(CN2C=CN3C(=O)C=C(N=C23)N4CCOCC4)c1,2.8 | |
| Nc1nc(O)cc(n1)c2ccc(O)cc2,1.05 | |
| O=C(NCc1ccccc1)c2cccnc2Oc3ccccc3,3 | |
| CC(C)CNc1nc(nc(N2CC(O)C2)c1N)C#N,2 | |
| CN(C)C(=O)N1CCC(CC1)C(=O)NCc2cccs2,1.1 | |
| CN(c1ccnc(Nc2cc(cc(c2)C(=O)N3CCOCC3)N4CCOCC4)n1)c5cc(CO)ccc5C,2.2 | |
| Fc1ccc(cc1Cl)S(=O)(=O)NCC(N2CCCCCC2)c3ccccc3,3.98 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)Cc4ccc(cc4)[N+](=O)[O-],4.1 | |
| Clc1ccc(cc1)c2c[nH]nn2,2.97 | |
| COc1cc(cc2cnc(Nc3ccc(cc3)[C@@H](C)NC(=O)C)nc12)c4ccncc4,2.73 | |
| CC(C)N1C(=O)N(C)C(=O)c2cn(Cc3cccc4ccccc34)cc12,3.97 | |
| CCCCCCCCCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H]3[C@@H](C)OC(=O)[C@H](CC(=O)c4ccccc4N)NC(=O)[C@@H](NC(=O)[C@@H](CO)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCN)NC(=O)CNC3=O)[C@H](C)CC(=O)O,-.94 | |
| C[C@H](Nc1nc(Nc2ncc(C)s2)cc(n1)N3CCOCC3)c4ncc(F)cn4,2.68 | |
| CC(C)N1CCN(Cc2cnc(c(C)c2)c3ccc(cc3)C(=O)Nc4ccccc4N)CC1,1.44 | |
| COc1ccccc1OCCNCC(O)COc2cccc3[nH]c4ccccc4c23,3.27 | |
| NC1(CCC1)c2ccc(cc2)c3nc4ccccc4cc3c5ccccc5,3.6 | |
| OC(=O)c1ccc(cc1)n2ncc(C(=O)NC3C4CC5CC(CC3C5)C4)c2C6CCC6,1.33 | |
| O=C1Nc2cc(ccc2C1c3ncnc4cc(OCCCN5CCOCC5)ccc34)C#N,2.99 | |
| CC(C)(C)C(=O)NCc1ccc(NC(=O)N2CCCC(O)(C2)c3ccc(Cl)c(Cl)c3)cc1,3.93 | |
| CC[C@H]1N(C2CCCC2)c3nc(Nc4ccc(cc4OC)C(=O)NC5CCN(C)CC5)ncc3N(C)C1=O,3.14 | |
| CCCCn1c(Cc2cc(OC)c(OC)c(OC)c2)nc3c(N)ncnc13,2.39 | |
| NC(=N)c1cc2c(OCc3ccccc3)cccc2s1,1.16 | |
| OC(=O)CCc1ccc(NCc2cccc(Oc3ccccc3)c2)cc1,2.1 | |
| CCCSc1nc(N[C@@H]2C[C@H]2c3ccccc3)c4nnn([C@@H]5C[C@H](OCCO)[C@@H](O)[C@H]5O)c4n1,3.87 | |
| Cc1c(N)cccc1CN2C=CC(=CC2=O)OCCc3cccs3,2.78 | |
| Cc1ccc(NC(=O)c2ccnc(c2)N3CCOCC3)cc1Nc4ccnc(Cl)n4,3.1 | |
| OC(=O)C[C@H]1[C@@H](Cc2ccccc12)NC(=O)c3cc4cc(Cl)ccc4[nH]3,1.79 | |
| COc1ccc(cc1Cl)C(=O)NCCN2CCN(Cc3ccc(Cl)c(Cl)c3)CC2,3.74 | |
| O[C@@H](CNCCc1cccc(CNCc2ccccc2Cl)c1)c3ccc(O)c4NC(=O)Sc34,1.85 | |
| CC(C)CC(N(C)C)C1(CCC1)c2ccc(Cl)cc2,3.6 | |
| Cc1cc(CNc2nccc(Nc3cc(CCc4ccccc4)[nH]n3)n2)on1,3.56 | |
| NC(=O)c1cccc(O[C@@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)c1,1.76 | |
| COc1cc(Nc2c(cnc3cc(OC)c(OC)cc23)C#N)cc(OC)c1,3.5 | |
| Cc1cc(CNc2ncc(Br)c(Nc3cc([nH]n3)C4CC4)n2)on1,3.43 | |
| CCCCC1(CC)C(=O)NC(=O)NC1=O,1.5 | |
| COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN4CCC[C@H]4CC(=O)N,2.64 | |
| COc1cc2ncnc(NCc3cccc(C)c3)c2cc1OC,3.5 | |
| COc1ccc(cc1)c2cc(O)nc(N)n2,1.52 | |
| OC(=O)c1ccc(NC(=O)c2cc(OCc3ccccc3)cc(OCc4ccccc4)c2)nc1,2.7 | |
| OCC(CO)CN1C(=O)C(Cc2ccccc12)NC(=O)c3cc4cc(Cl)ccc4[nH]3,3.64 | |
| CO[C@@H](C(=O)N1Cc2n[nH]c(NC(=O)c3ccc(cc3)N4CCN(C)CC4)c2C1)c5ccccc5,2 | |
| CCN(C1CCN(CC[C@H](N2CCN(CC2)S(=O)(=O)C)c3cc(F)cc(F)c3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,1.25 | |
| Cc1ccc(cc1)S(=O)(=O)Nc2ccc(\C=C\C(=O)Nc3ccccc3N)cc2,2.82 | |
| Clc1ccc(C2CCN(CC2)C(=O)COCc3ccncc3)c(Cl)c1,2.63 | |
| CC(C)N(CCNCCc1ccc(O)c2NC(=O)Sc12)C(=O)CCOCCc3ccccc3,2.33 | |
| CN(C\C=C\C#CC(C)(C)C)Cc1cccc2ccccc12,2.83 | |
| CCOc1ccc(cc1)c2cnc3CCCn23,2.65 | |
| C[C@@H](NC(=O)[C@@H]1CCCC[C@H]1C(=O)N2CCc3[nH]c4ccc(F)cc4c3C2)C#N,3.1 | |
| COc1ccc2nc(C)cc(OCC(=O)NCc3ccccc3)c2c1,3.2 | |
| CNC1=CN=C(N(CC(=O)NC(C(C)C)C(=O)C(F)(F)F)C1=O)c2ccc(F)cc2,1.86 | |
| CC(=O)Nc1ccc2c(c1)c(cn2CCC(=O)O)c3cc(NC4CC4)n5ncc(C#N)c5n3,-.87 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)N(C)C,3.7 | |
| CN1CCN(CC1)c2nc3ccccc3cc2Cn4nc(c5ccc6nc(N)sc6c5)c7c(N)ncnc47,3.09 | |
| Oc1cccc2ccc(nc12)C#N,1.81 | |
| COCCNC(=O)c1ccc(Nc2ncc3cc(ccc3n2)c4ccncc4OC)cc1,3.14 | |
| NCCCCCc1c[nH]c2ccc(F)cc12,.6 | |
| CN1C(=O)N(Cc2ccc(cc2)C(=O)O)C(=O)c3cc(ccc13)C#CCc4ccccc4,2.5 | |
| COc1c(cc2ccccc2c1C(=O)N(C)C[C@@H](CCN3CCC(CC3)c4ccc(O)cc4[S+](C)[O-])c5ccc(Cl)c(Cl)c5)C#N,3.5 | |
| CN1C(=O)N(C)c2ncn(C)c2C1=O,-.03 | |
| Cn1c(ccc1c2cc(F)c3NC(=O)C(C)(C)c3c2)C#N,3.21 | |
| CN(C)CC(O)COc1ccc(Nc2cc(ncn2)N(CCC#N)c3cc(Cl)ccc3Cl)cc1,2.1 | |
| OC1(CNC(=O)c2cc(ccc2Cl)N3N=CC(=O)NC3=O)CCCCCC1,.26 | |
| COc1ccccc1N2CCN(CCN(C(=O)C3CCCCC3)c4ccccn4)CC2,3 | |
| Fc1ccccc1NC(=O)N[C@H]2N=C(c3ccccc3)c4ccccc4NC2=O,4 | |
| CCC[C@@H](N1CCC[C@@H](C1)N2C=C(C)C(=O)NC2=O)c3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3,.6 | |
| CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)c2cc3sccc3[nH]2,3.1 | |
| Cc1cccc(Br)c1C(=O)N[C@@H](Cc2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)C(=O)O,-.13 | |
| C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc3nc(NS(=O)(=O)C)sc13,.92 | |
| Cc1nc(C)c(nc1C(=O)N)c2ccc3c(CC[C@@]34CC[C@@H](CC4)c5nnn[nH]5)c2,1.4 | |
| Brc1cnc(NCc2ccccc2)nc1Nc3cc([nH]n3)C4CC4,4.11 | |
| Cc1ccc(cc1NC(=O)CC23CC4CC(CC(C4)C2)C3)C(=O)N5CC6CNCC(C5)O6,2.12 | |
| C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]4(C)C=CC(=O)C=C14,2.12 | |
| C[C@H](Nc1nc(Nc2ncc(C)s2)cc(n1)N3CCN(C)CC3)c4ccc(F)cn4,2.9 | |
| CN(c1ccnc(Nc2cc(cc(c2)N3CCOCC3)N4CCOCC4)n1)c5cccc6[nH]ncc56,3.23 | |
| Fc1ccccc1NC(=O)NC2N=C(c3ccccc3)c4ccccc4NC2=O,3.8 | |
| CN1C(=O)C=C(CCc2ccc3cc[nH]c3c2)N=C1N,2.1 | |
| CC1=C(Cc2ccccc2)C(=O)n3nc(NCc4cccc(Cl)c4)nc3N1,3.6 | |
| Clc1ccc(Cl)c(c1)S(=O)(=O)Nc2nc(cs2)c3sccc3Cl,2.11 | |
| COc1cc2ncc(C(=O)N)c(Nc3ccccc3C)c2cc1OC,3.4 | |
| N[C@@H](Cc1cccs1)C(=O)N[C@]2(C[C@H]2c3ccccc3)C#N,1.5 | |
| COc1ccc(C)c(NC(=O)CC23CC4CC(CC(C4)C2)C3)c1,3.96 | |
| CC1=CN(C2CCCN(Cc3cccc(Oc4ccccc4)c3)C2)C(=O)NC1=O,3.04 | |
| Oc1cccc(NC(=O)c2ccc(OCCCN3CCCC3)cc2OCc4ccccc4)c1,3.07 | |
| C[C@@H](NC1=CC(=O)CNC1)c2ccc(Nc3ncc4cc(ccc4n3)c5ccncc5)cc2,2.49 | |
| CN1CCOc2cc(COc3ccccc3)cnc12,3.3 | |
| O[C@H](CNC(=O)c1c[nH]nc1C2CC2)CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,3.15 | |
| CCOc1noc2cc(OCCC3CCN(CC3)c4ccc(C)nn4)ccc12,4.23 | |
| CCC(N(CCCN)C(=O)c1ccc(C)cc1)C2=Nc3ccsc3C(=O)N2Cc4cscn4,.02 | |
| C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)nc(OC4CCC(F)(F)CC4)nc23,1.42 | |
| O[C@@H](CNCCc1cccc(CNCCc2ccccc2Cl)c1)c3ccc(O)c4NC(=O)Sc34,1.63 | |
| CC(C)n1c2ccccc2c3cc(NC(=O)N4CCOCC4)ccc13,3.55 | |
| CC(C)Oc1ccc(cc1C(=O)N2CCN(CC2)c3ccc(cc3)C(F)(F)F)S(=O)(=O)C,3.33 | |
| CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@H]2CCCN(Cc3ccccc3)C2,2.01 | |
| CN1CCN(CC1)C(=O)Cc2csc(NS(=O)(=O)c3cccc(Cl)c3C)n2,.57 | |
| CCOC(=O)c1cnc2c(N)cccc2c1O,.9 | |
| CN(c1ccnc(Nc2cc(cc(c2)N3CCOCC3)N4CCCOCC4)n1)c5cc(CO)ccc5C,3.3 | |
| N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O,-1.08 | |
| NS(=O)(=O)c1ccc(Nc2nccc(n2)c3cnc4ccccn34)cc1,2.7 | |
| COc1cc(OC)c(cc1NC(=O)CCC(=O)O)S(=O)(=O)N2C(C)CCc3ccccc23,-.87 | |
| Cc1cc(CN2Cc3cccnc3CC2C(=O)Nc4ccc(Cl)cc4Cl)ccc1OCC(=O)O,1.15 | |
| C1CN2CCC1C(C2)c3oc(nn3)c4oc(cc4)c5cccnc5,1.2 | |
| O=C(NC1(CC1)C#N)[C@@H]2CCCC[C@H]2C(=O)N3CCN(CC3)c4nc(cs4)c5ccccc5,3.5 | |
| NC1=CC2=NNC(=O)N2c3cc(ccc13)c4ccsc4,3.18 | |
| CCc1cccc(CC)c1NC(=O)N2Cc3[nH]nc(NC(=O)c4ccc(cc4)N5CCN(C)CC5)c3C2,3.31 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(C(=O)N)c(F)c3)ncc2F,3.14 | |
| [O-][N+](=O)c1cc(C(=O)NCC=C)c2N=C(Nc3ccc(Cl)c(Cl)c3)NC(=O)c2c1,2.7 | |
| c1ccc(cc1)c2cn3ccccc3n2,2.9 | |
| COC[C@H](O)CN1C(=O)C=NN(C1=O)c2ccc(Cl)c(c2)C(=O)NCC3(O)CCCCCC3,1.46 | |
| FC(F)(F)c1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(c1)C(F)(F)F,1.8 | |
| CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)O)[C@@H]12,1.55 | |
| NC(=O)c1cccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3CC4CCCCC4)c1,1.55 | |
| Oc1ccc(cc1)c2sc3cc(O)ccc3c2C(=O)c4ccc(OCCN5CCCCC5)cc4,4.13 | |
| OC(=O)c1ccccc1N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,2.83 | |
| COc1ccc(CC(=O)N(C)C2CCN(CCC(c3ccccc3)c4ccccc4)CC2)cc1OC,3.4 | |
| CCN1CCN(Cc2cnc(c(C)c2)c3ccc(cc3)C(=O)Nc4ccccc4N)CC1,1.2 | |
| CCC(N(CCCN)C(=O)c1ccc(C)cc1)C2=Nc3snc(C)c3C(=O)N2Cc4ccccc4,1.61 | |
| CCOC(=O)Cc1csc(NS(=O)(=O)c2ccc(Cl)cc2)n1,1.32 | |
| Clc1ccc2Oc3ccccc3N=C(N4CCNCC4)c2c1,2.28 | |
| Cc1cc2nc(NC(=N)N)nc(C)c2cc1C,.7 | |
| CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c3ccccc3)c4ccccc4)C(=O)CC(C)C,1.82 | |
| Cc1nc(C)c(s1)C(=O)N[C@@H](Cc2cccc(Cl)c2)C(=O)NCC#N,2 | |
| COc1ccc(cc1)c2nc3CCCn3c2Br,3.3 | |
| OC(=O)[C@H](Cc1ccc(cc1)C#N)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,2.17 | |
| CN1C[C@@H](c2ccccc2)c3cccc(N)c3C1,2.11 | |
| Cn1c(ccc1c2ccc3NC(=O)OC(C)(C)c3c2)C#N,2.85 | |
| CN([C@H](CN1CCCC1)c2ccccc2)C(=O)Cc3ccc(Cl)c(Cl)c3,3.42 | |
| Cn1c2ccccc2c3cc(NC(=O)CCc4ccncc4)ccc13,3.8 | |
| OC(c1ccccc1)c2ccc3C(=O)C=C(Nc3c2)c4cccnc4,2.27 | |
| CC(C)COc1ccc(cc1C#N)c2nc(C)c(s2)C(=O)O,.94 | |
| O[C@@H](CNCCc1cccc(CNCc2ccccc2F)c1)c3ccc(O)c4NC(=O)Sc34,.69 | |
| CN1C(=O)C=C(CCc2cccc(c2)c3cccnc3)N=C1N,2.5 | |
| NS(=O)(=O)c1cccc(Nc2nccc(Nc3c(Cl)ccc4OCOc34)n2)c1,2.97 | |
| CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(N3Cc4ccncc4C3)c(F)c2,3.02 | |
| CC1=C(Cc2ccccc2)C(=O)n3nc(NCc4cccc(Br)c4)nc3N1,3.68 | |
| CC(C)n1nc(c2ccc(C)cc2)c3c(N)ncnc13,3.2 | |
| O=C1CCOc2nc(OCc3ccccc3)ccc12,3.1 | |
| COc1ccc(OC)c(c1)c2c(F)ccc3c(N)c(nnc23)C(=O)NC4CC4,3.47 | |
| CC(C)N1CCO[C@@H](CN2CCN(CC2)C(=O)Nc3ccc(Cl)c(Cl)c3)C1,2.77 | |
| CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1CCCN(CCc2cccc(OC)c2)C1)C(C)(C)C,1.47 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(C(=O)N(C)C)c(F)c3)n2,2.74 | |
| OC(=O)[C@H](Cc1ccc(Cl)cc1)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,2.86 | |
| Cc1cc(C)nc(N)c1,.85 | |
| C[C@@H]1COCCN1c2cc(nc(n2)c3cccc4[nH]ccc34)C5(CC5)S(=O)(=O)C,2.7 | |
| Fc1cccc(CN2CCN(CC2)c3ccc4nnc(n4n3)C(F)(F)F)c1F,3.6 | |
| CCCCCCCN(CCc1ccc(OC(C)(C)C(=O)O)cc1)C(=O)Nc2ccc(F)cc2F,1.93 | |
| COc1ccc(cn1)[C@@]2(O)CC[C@H](CC2)N3CC[C@H](C3)NC(=O)CNC(=O)c4cccc(c4)C(F)(F)F,1.72 | |
| NC1(CCN(CC1)c2ncnc3[nH]ccc23)C(=O)N[C@@H](CCN4CCCCC4)c5ccc(Cl)cc5,2.4 | |
| CN(C)CCNc1cc(nc2cc(nn12)c3ccc(F)cc3)c4ccccc4,4.5 | |
| O=S(=O)(Nc1cccnc1)c2ccc3OCCOc3c2,1.34 | |
| CNCCC(Oc1ccccc1OC)c2ccccc2,.22 | |
| OC[C@H]1C[C@H]([C@H](O)[C@@H]1O)n2nnc3c(N[C@@H]4C[C@H]4c5ccccc5)nc(SCCC(F)(F)F)nc23,4.06 | |
| CC(=O)NCc1ccc(CN2CCN(CC2)c3ccc(F)cc3F)cc1,2.5 | |
| O=C(N1CCC1)c2ccc(cc2)C(=C3CCN(Cc4cscn4)CC3)c5cccc6cccnc56,2.52 | |
| Clc1ccc(cc1C(=O)NCC23CC4CC(CC(C4)C2)C3)N5CCNCC5,1.77 | |
| Fc1ccccc1Nc2oc(nn2)C(=O)Nc3ccc(cn3)N4CCOCC4,2.4 | |
| CN(C)CCC=C1c2ccccc2COc3ccccc13,2.15 | |
| CC[C@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1,3.63 | |
| NCC(O)(c1ccccc1)c2ccccc2,.9 | |
| [O-][N+](=O)c1cccc(c1)c2ccc(OCC(CCc3ccncc3)N4C(=O)CCC4=O)cc2,3.88 | |
| CC(Nc1ccccc1)C2=CC(=CN3C(=O)C=C(N=C23)N4CCOCC4)C,3.6 | |
| Cc1cc(N)c2cc(NC(=O)CC(=O)Nc3ccc4nc(C)cc(N)c4c3)ccc2n1,1.35 | |
| COc1cc2OC[C@H]3Oc4c5C[C@@H](Oc5ccc4C(=O)[C@H]3c2cc1OC)C(=C)C,3.57 | |
| Nc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1,2.64 | |
| Fc1ccc(cc1F)C(=O)Nc2ccc(Cl)nc2,3.31 | |
| CCN(CC)S(=O)(=O)c1ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c(Cl)c1,3.66 | |
| COc1cc(F)ccc1c2cncc(c2)C3CCCN3,1.1 | |
| COc1ccc(Nc2ccccc2C(=O)O)cc1,1.2 | |
| CN(C)CCCC(NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4ccc(Cl)cc4,1.4 | |
| C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc3ncc(C)nc13,3.5 | |
| COc1ccc2c(Oc3ccc(CC(=O)Nc4n[nH]c(C)c4C)c(OC)c3)ccnc2c1,3.78 | |
| C[C@H](Nc1nc(NC[C@@H](O)CO)c(Cl)c(Nc2cc([nH]n2)C3CC3)n1)c4ccc(F)cc4,3.39 | |
| CCCSc1c(cnn1[C@@H]2CC[C@H](CC2)C(=O)O)C(=O)NC3CCCCC3,1.03 | |
| c1cnc2cccnc2c1,.89 | |
| Oc1c(C#N)c(nc2ccncc12)c3ccc(cc3)c4ccccc4CN5CCOCC5,2 | |
| CS(=O)(=O)C1(CCNCC1)c2cc(nc(n2)c3cccc4[nH]ccc34)N5CCOCC5,.7 | |
| O=C(C1CC1)c2ccc(OCCCc3c[nH]cn3)cc2,2.68 | |
| Nc1nc2ccc(OC(F)(F)F)cc2s1,3.34 | |
| CN(C)Cc1ccccc1Sc2ccc(C)cc2N,2.6 | |
| Cc1cc(CN2CCc3ccccc3C2C(=O)Nc4ccc(Cl)cc4Cl)ccc1OCC(=O)O,2.63 | |
| CN(C1CCN(Cc2ccc(cc2)C(F)(F)F)CC1)C(=O)Cc3ccc(cc3)S(=O)(=O)C,2.5 | |
| O=C(N1CCCCC1)c2csc3CCCCc23,3.2 | |
| SC1=Nc2[nH]cnc2C(=O)N1,-1.48 | |
| Nc1ncnc2c1ncn2[C@@H]3O[C@H](CSCCCNC(=O)Nc4ccc(Cl)cc4)[C@@H](O)[C@H]3O,2.5 | |
| N#Cc1cccc(c1)c2onc(n2)c3ccccn3,2.2 | |
| COc1ccc2nccc(C(O)C3CC4(CCN3CC4)C=C)c2c1,2.08 | |
| Cn1cc(cn1)c2cccc(C[C@H](NC(=O)c3cc(nn3C)C(C)(C)C)C(=O)NCC#N)c2,2.6 | |
| OC1=NC(=O)C(N1)(c2ccccc2)c3ccccc3,2.41 | |
| C[C@H](Nc1ncc(F)c(Nc2cc([nH]n2)C3CC3)n1)c4ccc(F)cn4,3.14 | |
| CCC[C@@H](CN1CCCC1)N(C)C(=O)Cc2ccc(Cl)c(Cl)c2,2.27 | |
| COc1ccc2N=CC(=O)N(CCN3CCC(CC3)NCc4cc5OCCOc5cn4)c2c1,.93 | |
| CCN(CC)C(=O)c1ccc(cc1)C(N2CCNCC2)c3cccc4cccnc34,.7 | |
| CC1=C2C(=CC(=O)N1Cc3ccccn3)NN(C2=O)c4ccccc4Cl,.2 | |
| COc1ccc2N=NC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,-.65 | |
| Cc1ccccc1CN2CCC(CC2)N3CCC(CC3)N4C(=O)Nc5ccccc45,2.68 | |
| O=C(CSc1ccccc1)N2CCN(CC2)c3ccccc3,3.2 | |
| CCN(CC)CCCNCc1cc(Cl)c2cccnc2c1O,.72 | |
| O[C@@H](CNCCc1ccc(CNCCc2ccccn2)cc1)c3ccc(O)c4NC(=O)Sc34,-.25 | |
| Clc1ccc2OCOc2c1Nc3ncnc4cc(OCCN5CCCC5)cc(OC6CCOCC6)c34,2.6 | |
| CCN1C=C(C(=O)O)C(=O)c2ccc(C)nc12,-.1 | |
| CC(C)[C@H](NC(=O)N(C)Cc1csc(n1)C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](Cc2ccccc2)NC(=O)OCc3cncs3)Cc4ccccc4,4.3 | |
| CSc1ncccc1C(=O)NCC2CCCCC2,2.93 | |
| Cc1c(F)cc(cc1c2ccc(cn2)C(=O)NCC(C)(C)C)C(=O)NC3CC3,3.5 | |
| COc1ccccc1C(=O)Nc2ccc(C)c(c2)N3C=Nc4ccc(cc4C3=O)N5CCN(C)CC5,2.93 | |
| COc1ccc(cc1)c2cc(N)n3ncc(C#N)c3n2,2.42 | |
| CN(C)CCNS(=O)(=O)c1ccc(Nc2nccc(n2)c3cnc4ccccn34)cc1,2.7 | |
| COCCCCC(=NOCCN)c1ccc(cc1)C(F)(F)F,1.55 | |
| CNC1=Nc2ncccc2C(=NC1c3cccs3)c4ccccc4,2.68 | |
| CCN1C2=NC(=O)N(C)C(=O)C2=Cc3ccccc13,1.1 | |
| CN(C)c1cccc(c1)C(=O)Nc2ccc(C)c(c2)C(=O)Nc3cccnc3,3.01 | |
| NC(=O)c1ccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)cn1,1.51 | |
| CCc1nn(C2CCCC2)c3c1CCn4c(nnc34)c5cccs5,3.6 | |
| CCCN1CCC(CC1)Oc2nccc(Nc3cc(NC(=O)c4cccc(c4)N5CCOCC5)ccc3C)n2,2.6 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4cc(C)ccn34)N5CCN(CC5)C(=O)C,3.3 | |
| COc1cnc(nc1N2CCOCC2)c3ccccn3,1.52 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccc(cn3)S(=O)(=O)C)cn2)C(=O)OC(C)(C)C,3 | |
| Nc1nccc(n1)c2cc3C(=O)NC[C@H](CCF)c3[nH]2,.51 | |
| COc1ccc(cc1)c2nc3c(NCC4CCNCC4)c(Br)cnc3[nH]2,1.36 | |
| CCCSc1nc(Oc2ccc(CC(=O)O)cc2)ccc1C(=O)NC3CCCCC3,1.79 | |
| O=C(Nc1ccc(cc1)N2CCOCC2)c3oc(Nc4ccccc4)nn3,3.15 | |
| CNC(=O)c1[nH]cnc1C(=O)Nc2ccc(OC)cc2,2.2 | |
| Cc1ccc([nH]1)C(=O)NC2CCN(CC2)c3cc(cc(Cl)n3)C(=O)N,2.64 | |
| COC(=O)C1=C(C)NC(=C(C1c2ccccc2[N+](=O)[O-])C(=O)OC)C,3.29 | |
| Fc1ccc(CC2=NNC(=O)c3ccccc23)cc1C(=O)N4CCN(CC4)C(=O)C5CCCO5,.9 | |
| O=C(Nc1ccccc1)c2ccc(OCCCN3CCCC3)cc2OCc4ccccc4C#N,2.66 | |
| COc1cccc(c1)[C@@H](C)NCCCc2ccccc2Cl,3 | |
| CN1CCN(CC1)c2ccc3N=CN(C(=O)c3c2)c4cc(NC(=O)c5cocc5)ccc4C,2.43 | |
| COc1cccc(c1)C(=O)Nc2ccc(C)c(c2)N3C=Nc4ccc(cc4C3=O)N5CCN(C)CC5,3.08 | |
| COc1ccc(CNC(=O)c2ccc(Oc3ccc(cc3)C#C[C@]4(O)CN5CCC4CC5)cc2)nc1,3.1 | |
| Cn1cc(cc1c2c3C(=O)N(CC#CCn4cncn4)C(=O)N(CC5CC5)c3nn2Cc6ccnc7ccc(Cl)cc67)C#N,3.43 | |
| CCNCc1cncc(n1)c2ccc(F)cc2OC,1.18 | |
| COc1cc(cc(OC)c1OC)C(=O)NCc2ccc(OCCN(C)C)cc2,.74 | |
| CCCNC(=O)c1nnc2c(c(F)ccc2c1N)c3ccc(OC)cc3OC,3.52 | |
| CC(C)OC(=O)N1CCC(CC1)Oc2ncnc3N(CCc23)c4ccc(cc4F)S(=O)(=O)C,3.4 | |
| CCO\N=C(\C1CCN(CC1)C2(C)CCN(CC2)C(=O)c3c(Cl)cncc3Cl)/c4ccc(Br)cc4,4 | |
| C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)nc(OCC4CC45CC5)nc23,1.78 | |
| CCN(C1CCN(CCC(N2CCN(CC2)c3cccc(F)c3)c4ccccc4)CC1)C(=O)Cc5ccc(cc5)S(=O)(=O)C,3.21 | |
| FC(F)(F)c1cccc(c1)S(=O)(=O)NC(=O)N2CCC(CC2)N3CCC(CC3)Oc4ccc(Cl)c(Cl)c4,2.94 | |
| OC(=O)CCC(=O)N1CCC(CC1)c2onc(n2)c3cccs3,-1.27 | |
| Oc1ccc2C(=O)N(C(=O)c2c1)c3ccccc3,2.3 | |
| COc1ccc2C=CC(=O)N(CCN3CCC(CC3)NCc4cc5OCCOc5cn4)c2n1,1.16 | |
| Cc1cc(C)nc(SCC(=O)N)n1,.23 | |
| Cc1oc(CN2NC(=O)C3=C(C2=O)C(=O)c4ccc(Cl)cc4N3)cc1C,1 | |
| O[C@@H](CNCCCSCCNCCc1cccc(Cl)c1)c2ccc(O)c3NC(=O)Sc23,1.06 | |
| Cc1ccsc1C(=CCCN2CCC[C@H](C2)C(=O)O)c3sccc3C,1.49 | |
| CC1Cc2ccccc2N1NC(=O)c3ccc(Cl)c(c3)S(=O)(=O)N,1.83 | |
| C[C@H]1CN(Cc2cc(Cl)ccc2CC(=O)O)CCN1C(=O)Cc3ccc(Cl)cc3,1.66 | |
| C[C@@](N)(Cc1ccccc1)c2ccccc2,1.7 | |
| Cc1cc(CN2Cc3ccccc3C2C(=O)Nc4cc(Cl)ccc4Cl)ccc1OCC(=O)O,2.19 | |
| CCC(CC)NC(=O)c1c(C)nn(C(C)C)c1NS(=O)(=O)c2ccc(C)cc2,.92 | |
| Cc1ccc(cc1NC(=O)c2ccc(OCc3ccccn3)cc2)c4cc(n[nH]4)C(F)(F)F,2.44 | |
| ONC(=O)Cc1ccc(OCc2ccccc2)cc1,1.92 | |
| CS(=O)(=O)c1cccc(Nc2nccc(n2)N(CC#N)c3c(Cl)ccc4OCOc34)c1,3.16 | |
| CN(CCOc1ccccc1c2cc(C(=O)N)c(NC(=O)N)s2)Cc3ccccc3,3.46 | |
| Nc1nc(N)c2nc(CO)cnc2n1,-.45 | |
| CCOC(=O)Nc1ccc(NCc2ccc(F)cc2)nc1N,2.22 | |
| OC(=O)c1ccccc1NC(=O)Nc2ccccc2,-.12 | |
| CC(NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4ccccn4,1.3 | |
| Cc1nc(NC(=N)N)nc2ccccc12,-.49 | |
| CNC(=O)c1ccc(Nc2nccc(n2)c3cnc(C)n3C(C)C)cc1,2.69 | |
| COC(=O)C1=C(C)NC(=C(C1c2ccccc2[N+](=O)[O-])C(=O)OCC(C)C)C,3.59 | |
| Clc1ccccc1CN2CCc3sccc3C2,3.46 | |
| Cc1[nH]c2ccccc2c1CCNCc3ccc(\C=C\C(=O)NO)cc3,1.1 | |
| OCCN1C(=O)C(Cc2ccccc12)NC(=O)c3cc4cc(Cl)sc4[nH]3,3.05 | |
| NC(=O)c1ccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3Cc4ccccc4)nc1,1.25 | |
| NC(=O)c1cnc(N[C@H]2CCCNC2)c3cc(Br)sc13,1.08 | |
| CCC(CC)NC(=O)c1c(C)nn(c1NS(=O)(=O)c2ccc(C)cc2)c3ccccc3,1.35 | |
| OC(=O)C[C@@H]1CC[C@H](CC1)c2ccc(NC(=O)c3oc(Nc4ccccc4F)nn3)cc2,2.48 | |
| NCC[C@@H](Sc1cc(Cl)ccc1C#N)c2ccccc2,1.26 | |
| FC(F)(F)Oc1cccc2c3CN(CCc3[nH]c12)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N,4.01 | |
| Clc1ccc(NC(=O)N2CCN(C[C@@H]3CCCN(CC4CC4)C3)CC2)cc1Cl,2.54 | |
| CN1CCN(CC1)c2ccc3N=CN(C(=O)c3c2)c4cc(NC(=O)c5cccc(c5)N6CCOCC6)ccc4C,2.69 | |
| OC(=O)c1cncc(c1)c2ccc(Cl)c(c2)C(=O)NCC34CC5CC(CC(C5)C3)C4,.85 | |
| COc1cncc(NC(=O)c2cc(NC(=O)c3cccc(c3)C(C)(C)C#N)ccc2C)c1,3.04 | |
| Nc1nc(nc2c1nc(O)n2Cc3ccccc3)c4ccccc4,4.16 | |
| [O-][N+](=O)c1ccc2c(c1)C(=O)C(=O)c3ccccc23,2.42 | |
| CC(C)Nc1ccc2cnn(c3cncc(n3)n4ccc(CC(=O)O)c4)c2c1,1.24 | |
| NC1=NC(c2cccc(c2)c3cncnc3)(c4ccnc(c4)C(F)(F)F)c5cccc(F)c15,3.4 | |
| Cc1sc(nc1C(F)(F)F)N2CCN(CC2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NC4(CC4)C#N,2.87 | |
| COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(C)C4(CCN(C)CC4)C(=O)N,2.16 | |
| COC(=O)c1c(C)[nH]c(C)c1C(=O)c2ccccc2Cl,2.7 | |
| CNc1c(Br)cnc2[nH]c(nc12)c3ccc(O)cc3,2.47 | |
| CCNC(=O)c1ccc(CN2CCC(CC2)c3ccc(cc3)C(=O)Nc4ccccc4N)cc1,2.24 | |
| COCCOc1cc(Nc2nccc(n2)N(C)c3cc(CO)ccc3C)cc(c1)N4CCOCC4,3.3 | |
| COc1cc(Nc2cc(Oc3cccnc3)ccn2)cc(OC)c1OC,2.66 | |
| C[C@@H]1CN[C@@H](C2CC2)C(=O)N(C)[C@H](C)C(=O)N[C@H](Cc3ccc(F)cc3)C(=O)NCCCc4ccccc4O1,3.3 | |
| CC[C@H](NC(=O)c1c([S+](C)[O-])c(nc2c(F)cccc12)c3ccccc3)c4ccccc4,2.84 | |
| Cc1ccc2cc(C)c3nnc(SCC(=O)N4CCN(CC4)C(=O)c5occc5)n3c2c1,2.3 | |
| Nc1ccc2cccc(Nc3ncccn3)c2n1,2.7 | |
| O=C1C=C(N=C2C=CC=CN12)N3CCOCC3,1 | |
| Clc1ccc(cc1Cl)C2CNCC=CC2,1.86 | |
| Oc1cc(O)c2C(=O)C(=COc2c1)c3ccc4OCOc4c3,3.5 | |
| N(c1ccccc1)c2ncnc3ccccc23,2.94 | |
| FC(F)(F)Oc1ccc2OCC(=O)N(CCN3CCC(CC3)NCc4ccc5OCC(=O)Nc5n4)c2c1,1.82 | |
| Nc1c(NC2CCCCC2)nc(nc1N3CCOCC3)C#N,2.81 | |
| OC(CCN1CCCC1)(C2CCCCC2)c3ccccc3,1.78 | |
| COc1cc(F)ccc1c2cncc(CNC(=O)c3cnccn3)c2,2.5 | |
| COc1cc(cc(OC)c1OC)c2nnc(S)n2c3cccc(c3)C(F)(F)F,2.27 | |
| COCCOc1ccc(cc1)c2cc(C(=O)N)c(NC(=O)N)s2,2.34 | |
| C[C@H](NC1=NC(=O)[C@](C)(S1)C(F)(F)F)c2ccccc2F,3.1 | |
| Fc1ccc(NC(=S)N2CCC(CC2)C(=O)c3ccc(F)cc3)cc1,3.4 | |
| COc1cc(F)ccc1c2cccc(CNC3CCCC3)n2,2.06 | |
| CC(C)n1c(C)ncc1c2ccnc(Nc3ccc(cc3)C(=O)NC4CCN(C)CC4)n2,1.87 | |
| NS(=O)(=O)c1cccc2c3nc(O)c(O)nc3cc(c12)[N+](=O)[O-],.36 | |
| Nc1c(nc(nc1N2CCOCC2)C#N)N3CCCCC3,2.71 | |
| Brc1ccc(OC(=O)N2CCN3CCC2CC3)cc1,1.58 | |
| COc1ccc(COc2nc(Br)cnc2NS(=O)(=O)c3ccc(C)cc3)cc1OCCN(C)C,1.68 | |
| CCN(C1CCN(CC[C@H](c2ccc(cc2)S(=O)(=O)C)c3cccc(F)c3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,2.9 | |
| COc1ccc(cc1OC)C(=O)Nc2cccc(NC(=O)c3cccc(c3)N(C)C)c2,3.67 | |
| OC(=O)COc1ccc(Cl)cc1CN2CCC(CC2)S(=O)(=O)c3ccccc3,.48 | |
| COc1cc(OC2CCN(C)CC2)c3c(Nc4cccc5OCOc45)ncnc3c1,3.02 | |
| CC[C@H](N)C(=O)N[C@@H](Cc1ccc(cc1)c2ccccc2)C#N,2.6 | |
| OC(=O)CCc1ccc(OCc2cccc(Oc3ccccc3)c2)cc1,2.47 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4ccccn34)C(CO)CO,3.1 | |
| COc1cc2c3N([C@H](C)c4ccccn4)C(=O)Nc3cnc2cc1c5c(C)onc5C,3.15 | |
| COc1cc2c(Nc3ccc(NC(=O)c4ccccc4)cc3)ncnc2cc1OCCCN5CCOCC5,3.5 | |
| CNS(=O)(=O)c1ccc(Nc2nccc(n2)c3cnc4cccnn34)cc1,2.8 | |
| OCCn1cc(cn1)c2cnc3nnn(Cc4ccc5ncccc5c4)c3n2,1.7 | |
| NC(=O)C(NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4ccc(Cl)cc4,2.2 | |
| NC(=O)C1CCN(CC(=O)Nc2ccc3OCOc3c2)CC1,.4 | |
| CC(O)(C(=O)Nc1ccc(cc1)S(=O)(=O)c2ccccc2)C(F)(F)F,2.98 | |
| CC(C)(Cc1cccc(CC(=O)NCc2cccc(c2)c3ccc(O)cc3)c1)NC[C@H](O)c4ccc(O)c(NS(=O)(=O)C)c4,1.91 | |
| COCCN(c1ccnc(Nc2cc(cc(c2)N3CCOCC3)N4CCOCC4)n1)c5cc(CO)ccc5C,2.8 | |
| Cc1ccc(NC(=O)[C@@H]2CCCN2S(=O)(=O)c3cccc4cccnc34)c(C)c1,3.8 | |
| OCCCNc1ccc2c(NC(=O)CC3CCCCC3)c(Cl)ccc2n1,3.29 | |
| O=C(Nc1ccncc1)c2cccc3ccccc23,3.1 | |
| O[C@@H]1CN(CCN2C(=O)C=Cc3ccc(cc23)C#N)CC[C@@H]1NCc4cc5OCCOc5cn4,.46 | |
| CNc1ncnc2c(CNc3cc(NC(=O)c4ccc5OCCOc5c4)ccc3C)cccc12,4 | |
| Oc1cccc2nc(cc(O)c12)c3ccccc3,3.37 | |
| CC(C)Oc1cc(OCCN2CCN(CC2)C(=O)C)cc3ncnc(Nc4c(F)ccc5OCOc45)c13,3.06 | |
| NC(=O)Cc1nc(cs1)c2ccccc2,1.3 | |
| COC(=O)N1CCN(C(CC(=O)NCc2ccc3OCOc3c2)C1)c4ccnc(n4)n5ccnc5,1.88 | |
| C(C1NCCc2ccccc12)c3ccccc3,1.89 | |
| CC(C)N1CCC(CC1)N(C(=O)Cc2ccccc2)c3ccc(Cl)cc3,2.3 | |
| CN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)Cc4ccc(O)cc4,3.3 | |
| OC(=O)c1cc2cc(ccc2n1Cc3ccc(Cl)c(Cl)c3)[N+](=O)[O-],1.79 | |
| CN1CCN(CC1)C2=Nc3ccccc3Nc4sc(C)cc24,2.19 | |
| Cc1cc(F)ccc1OC2CCN(CC3CCN(CC3)[C@@](C)(Cc4ccc(F)cc4)C(=O)O)CC2,2 | |
| CCN1CCC[C@H](CN2CCN(CC2)C(=O)Nc3ccc(Cl)c(Cl)c3)C1,1.86 | |
| COCC(C)n1nc(C)c(C(=O)N[C@@H](C)C(C)(C)C)c1NS(=O)(=O)c2ccc(C)cc2,.61 | |
| OC(Cn1cncn1)(Cn2cncn2)c3ccc(F)cc3F,.48 | |
| COc1ccc(N(C(C(=O)NC2CCCC2)c3ccccc3F)C(=O)C)c(OC)c1,2.81 | |
| c1ccc(nc1)c2n[nH]cc2c3ccnc4ccccc34,2.57 | |
| Clc1ccccc1CNC[C@@H]2CC[C@@H](CNCc3ccccc3Cl)CC2,2.74 | |
| CCC[C@H](N1CCC[C@@H](C1)N2C=C(C)C(=O)NC2=O)c3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3,.5 | |
| CC1=CN([C@H]2CCCN(C2)S(=O)(=O)c3ccc(O)c(Oc4ccc(Cl)c(C)c4)c3)C(=O)NC1=O,2.4 | |
| C[C@H](NC(=O)\C=C\c1ccccc1)c2cccc(c2)N3CCOCC3,3.24 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1nn(Cc3cccc4ccccc34)c2c5cncn5C,4.1 | |
| COCCNc1nc(nc(NCC(C)C)c1N)C#N,2.8 | |
| Nc1nccc2ccccc12,1.5 | |
| CC(C)n1c(C)ncc1c2nc(Nc3ccc(cc3)C(=O)N4CCN(C)CC4)ncc2F,2.49 | |
| CO[C@@H]1C[C@@H](N(Cc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC)C1)C(=O)N,3.09 | |
| CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1CCCN(CCc2ccccc2OC)C1)C(C)(C)C,1.61 | |
| Nc1ncc(cc1c2oc3ccccc3n2)c4cnn(c4)C5CCOCC5,4 | |
| CCN(C1CCN(CC[C@H](C2CCN(CC2)S(=O)(=O)C)c3ccccc3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,1.05 | |
| O=C1N2C=CC=CC2=Nc3ccccc13,2.1 | |
| CN(c1ccnc(Nc2cc(nc(n2)N3CCOCC3)N4CCOCC4)n1)c5cc(CO)ccc5C,3.9 | |
| CCCNC(=O)c1nnc2c(c(F)ccc2c1N)c3ncccn3,2.07 | |
| CCC(N(CCCN)C(=O)c1ccc(C)cc1)C2=Nc3ccn(C)c3C(=O)N2Cc4ccccc4,1.8 | |
| COC(=O)c1cccc(CN2NC(=O)C3=C(C2=O)C(=O)c4ccc(Cl)cc4N3)c1,1.1 | |
| CCN1CCN(CC1)C(=O)c2cc3ccccc3[nH]2,1.95 | |
| C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)nc(Oc4ccccc4)nc23,1.05 | |
| Cc1ccc(NC(=O)N2CCN(C[C@@H]3CCCN(C3)C4CC4)CC2)cc1Cl,3.37 | |
| COc1cc(Nc2ncc(C)s2)nc(N[C@@H](C)c3ncc(F)cn3)n1,2.99 | |
| OC(=O)c1[nH]c2ccccc2c1CC(=O)Nc3cccc(c3)C(F)(F)F,1.33 | |
| CC(C)(C)c1ccc(cc1)C2=NC(=O)C(CC(=O)O)S2,-.1 | |
| C[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1C(=O)Cc3cccc(Cl)c3,.78 | |
| O=C(Oc1ccc2C(=O)CCOc2c1)c3ccccc3,3.6 | |
| COc1ccc2c(Oc3ccc(CC(=O)Nc4cn(C)nc4C)c(OC)c3)ccnc2c1,3.5 | |
| O=C(Nc1cc(ccn1)c2ccnc(Nc3ccccc3)c2)C4CCOCC4,3.7 | |
| COc1ccc(cc1)c2nc3c(NCCCNC(=O)C4(CN)CC4)c(Br)cnc3[nH]2,1.9 | |
| COc1cccc(OC)c1c2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2,-.27 | |
| COc1cc(OC)c(cc1NC(=O)\C=C\C(=O)O)S(=O)(=O)N2c3ccccc3Oc4ccccc24,-.71 | |
| C[C@H](Nc1nc(Nc2cc([nH]n2)C3CC3)cnc1C#N)c4ccc(F)cn4,3.18 | |
| COc1ccccc1Oc2c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)nc(nc2OCCO)c4ncccn4,1.03 | |
| NC1(CCC1)c2ccc(cc2)C3=Nc4ccccc4C(=O)N3c5ccccc5,1.5 | |
| OC(C(=O)c1ccccc1)c2ccccc2,2.13 | |
| CC(=O)Nc1ccc(O)cc1OC[C@@H](O)CN2CCC3(CC2)Cc4cc(F)ccc4O3,2.1 | |
| COc1cccc(Nc2ncnc3cc(OC)c(OC)cc23)c1,3.1 | |
| COc1cc2ncc(C(=O)N)c(Nc3ccc(C)cc3F)c2cc1OC,3.34 | |
| CN(c1ccc(c(Cl)c1)c2cc(F)ccc2OCC(=O)O)S(=O)(=O)C,-1.17 | |
| Nc1cc(nc2c(cnn12)C#N)c3ccccc3,2.48 | |
| CN1CCN(CC1)S(=O)(=O)c2ccc(cc2)c3cnc(N)c(n3)C(=O)Nc4cnccc4CN5CCCC5,3.28 | |
| N[C@@H](Cc1ccc(F)cc1)C(=O)O,-1.06 | |
| CN1[C@@H]2CC[C@H]1C[C@H](C2)OC(=O)C(CO)c3ccccc3,-.66 | |
| Brc1ccc(cc1)C2NC(=O)c3ccccc3N2,2.68 | |
| COc1cc(nc2c(cc(F)cc12)N3CCN(C)CC3)C(=O)Nc4ccc(cc4)N5CCOCC5,3.85 | |
| CCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(c1)C(=O)C,-.27 | |
| CN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)Cc4ccc(cc4)C#N,3.7 | |
| Cc1c(Cl)ccc(OC2CCN(CC3CCN(CC3)[C@@H](Cc4ccc(F)cc4)C(=O)O)CC2)c1Cl,3.15 | |
| OC(=O)C1CCn2c1ccc2C(=O)c3ccccc3,-.93 | |
| CN1C2CCC1CC(C2)OC(=O)C(CO)c3ccccc3,-.09 | |
| C[C@@H]1CN(CCN1c2ncc(OCc3ccncc3C#N)cn2)c4noc(n4)C(F)(F)F,3.95 | |
| CC(=O)c1ccc(cc1)S(=O)(=O)NC(=O)NC2CCCCC2,-.49 | |
| NC(=O)Nc1sc(cc1C(=O)N)c2ccc(CN3CCCCC3)cc2,1.75 | |
| Cc1oc(CN2CCNCC2)cc1C(=O)NCC34CC5CC(CC(C5)C3)C4,1.03 | |
| C[C@H](CO)Nc1nc(SCc2ccccc2F)nc3NC(=O)Sc13,3 | |
| OC(=O)COc1ccc(Br)cc1c2ccccc2,.15 | |
| CN1CCC(=C2c3ccccc3C=Cc4ccccc24)CC1,3.06 | |
| CCC(=O)N1CCN(CC1)C(=O)c2cc(CC3=NNC(=O)c4ccccc34)ccc2F,1.22 | |
| CCCOc1cc(OCCCN2CCCC2)ccc1C(=O)Nc3cccc(O)c3,2.46 | |
| CC(=O)N1CCOc2cc(COc3ccccc3)cnc12,2.8 | |
| Cc1sc(N)nc1c2ccccc2,2.75 | |
| CN(C)C(=O)c1ccc(cc1)C(=C2CCN(Cc3cscn3)CC2)c4cccc5cccnc45,2.3 | |
| Cc1ccc(\C=C(/C#N)\C(=O)N)cc1,2.09 | |
| CC1=CC2=NNC(=O)N2c3cc(ccc13)c4cccnc4,2.72 | |
| Nc1ccccc1[N+](=O)[O-],-.96 | |
| C1CN2CCC1C(=C2)c3oc4ccccc4c3,2.59 | |
| OCC1=CC2=NNC(=O)N2c3cc(ccc13)c4ccc[nH]4,2.19 | |
| Nc1ccc2c3ccccc3C(=O)c2c1,2.9 | |
| Clc1ccc(CNc2nc(nc3ncccc23)N4CCN(CC4)C(=O)[C@H]5CCCCN5)c(Cl)c1,2.27 | |
| Nc1ncnc2sc(nc12)c3c(ncn3Cc4ccccc4N5CCOCC5)c6ccccc6,3.58 | |
| CC1=CN([C@H]2CCCN(C2)[C@H](CC3CCCCC3)c4ccc(C(=O)O)c(Oc5cccc(Cl)c5)c4)C(=O)NC1=O,1.83 | |
| CN1CCN(CCOc2n[nH]c3ncnc(Nc4ccc(OCc5ccccn5)c(Cl)c4)c23)CC1,2.45 | |
| NC(=O)N1c2ccccc2C=Cc3ccccc13,1.65 | |
| CCCN1CCN(CC1)c2ccc(cc2)C(=O)NC3(CCCCC3)C(=O)NCC#N,1.33 | |
| CC(C)Oc1cccc(CC(=O)N2CCC[C@@](CC[N+]34CCC(CC3)(CC4)c5ccccc5)(C2)c6ccc(Cl)c(Cl)c6)c1,1.23 | |
| COc1nc(Br)cnc1NS(=O)(=O)c2ccc(Cl)s2,.99 | |
| CC(C)NC(=O)c1ccc2c(Nc3ccc(Cl)cc3)nc(nc2c1)N4CCOCC4,2.78 | |
| Oc1ncnc2scc(c3ccccc3)c12,2.07 | |
| NC1(CCN(CC1)c2ncnc3[nH]ccc23)C(=O)NC(CCCN4CCOCC4)c5ccc(Cl)cc5,2.7 | |
| COc1cc(ccc1Nc2nccc(n2)c3cnc4ccccn34)N5CCN(CC5)C(=O)C,3 | |
| Cc1onc(c2ccccc2)c1c3ccc(cc3)S(=O)(=O)N,2.37 | |
| O=C1NC(=O)C(Cc2cccc(Oc3ccccc3)c2)S1,2.84 | |
| CCCc1c(cnn1c2ccccc2)C(=O)Nc3ccc(F)cc3C,3.89 | |
| OCCNC(=O)CN1C(=O)C(Cc2ccccc12)NC(=O)c3cc4cc(Cl)sc4[nH]3,3.05 | |
| Cc1ccc(cc1NC(=O)c2ccc(OCc3ccccn3)cc2)c4nc5ccccc5[nH]4,3.24 | |
| O[C@@H](CNCCOc1cccc(CNCCc2ccccc2F)c1)c3ccc(O)c4NC(=O)Sc34,1.86 | |
| Clc1ccc2OCOc2c1Nc3ncnc4cc(OCCCN5CCCC5)cc(OC6CCOCC6)c34,2.3 | |
| O=C(NCC#N)[C@@H]1CCCC[C@H]1C(=O)N2CCN(CC2)c3ccccc3,1.75 | |
| CC1=CN([C@H]2CCCN(C2)S(=O)(=O)c3ccc(C(=O)O)c(Oc4ccc(Cl)c(Cl)c4)c3)C(=O)NC1=O,-.87 | |
| CC(C)C(NC(=O)CN1C(=O)C2=C(C=C1c3ccccc3)C(=O)N(CCN4CCOCC4)C(=O)N2)C(=O)C(F)(F)F,1.91 | |
| Clc1cccc(c1)S(=O)(=O)NCC(N2CCCCCC2)c3ccccc3,3.39 | |
| C[C@H](Oc1nc(Nc2cc(C)[nH]n2)c(C)nc1C#N)c3ccc(F)cn3,2.86 | |
| CO[C@@H]1CC[C@@]2(CC1)Cc3ccc(cc3C24N=C(C)C(=N4)N)c5cc(Cl)cc(c5)C#N,3.8 | |
| Cn1cnc2c(c3ccc(cc3)C4(N)CCC4)c(ccc12)c5ccccc5,2.5 | |
| CC(C)NC(=O)c1cc2c(c(cnc2[nH]1)c3cncc(c3)C(=O)O)n4ccc(n4)C(F)(F)F,-.62 | |
| Cc1[nH]c(C(=O)NC2CCN(CC2)c3ncc(s3)C(=O)O)c(Cl)c1Cl,.02 | |
| COc1cc(OC2CCNCC2)ccc1Nc3ncc(Cl)c(n3)c4cnc5ccccn45,1.8 | |
| CC(C)CCOc1ccc(N)cc1,2.67 | |
| CC(C)c1ccc(Sc2cnc(O)c(c2)C(=O)NCc3ccccc3)cc1,3.7 | |
| Cc1ccc2c(c1)c(c(C)n2CC(=O)O)c3ccnc4c(C)cccc34,1.29 | |
| Fc1ccccc1Nc2oc(nn2)C(=O)Nc3ccc(Oc4cccnc4)nc3,3.1 | |
| CN(C)CCCOc1nn(Cc2ccccc2)c3ccccc13,2.4 | |
| Cc1ccc(cc1)c2nnc(N3CCN(CC3)C(=O)c4occc4)c5ccccc25,3.78 | |
| CC(=O)Nc1ccc(CNc2[nH]nc3cccc(Oc4ccc(cc4)S(=O)(=O)C)c23)cc1,2.63 | |
| CCS(=O)(=O)c1ccc(c(C)c1)c2cc(ccc2CCC(=O)O)C(F)(F)F,.76 | |
| COc1ccc(OC)c(CNc2n[nH]c3ccnc(Oc4ccccc4)c23)c1,4.25 | |
| CC(C)Cc1ccc(cc1)[C@H](C)C(=O)NS(=O)(=O)C,.56 | |
| COCCC(NC(=O)C1(N)CCN(CC1)c2ncnc3[nH]ccc23)c4ccc(Cl)cc4,2.95 | |
| COc1cc(OC)c(cc1NC(=O)NCC(=O)O)S(=O)(=O)N2C(C)CCc3ccccc23,-1.02 | |
| NC(=O)Nc1cc(sc1C(=O)N)c2ccsc2,2.3 | |
| COc1cc(F)ccc1c2cncc(CNCC3CC3)n2,1.8 | |
| CCCNC(=O)c1cc2c(c(cnc2[nH]1)c3cncc(c3)C(=O)O)n4ccc(n4)C(F)(F)F,-.79 | |
| COc1cc(OC2CCN(C)CC2)c3c(Nc4cccc5OCCOc45)ncnc3c1,2.26 | |
| FC(F)(F)Oc1ccccc1S(=O)(=O)NCC(N2CCCCCC2)c3ccccc3,4.09 | |
| CC(C)COc1cc(ccc1NC(=O)CN2CCOCC2)c3cccc4C(=O)C=C(Oc34)N5CCOCC5,3.8 | |
| CN1CCOc2cc(OC(=O)c3ccccc3)cnc12,3.3 | |
| Nc1sc2CCCCc2c1C(=O)NCc3ccccc3,3.52 | |
| CN1CCC(CC1)Oc2cccc3ncnc(Nc4ccc(OCc5cnccn5)c(Cl)c4)c23,3.21 | |
| CC(C)CNc1nc(nc(N2CCN(CC2)C(=O)C)c1N)C#N,2.4 | |
| CC(C)COCC(CN(Cc1ccccc1)c2ccccc2)N3CCCC3,3.66 | |
| CC1=CC2=NNC(=O)N2c3cc(ccc13)c4cccc(CO)c4,3.36 | |
| O[C@H](C[C@H](O)\C=C\c1c(nc2ccccc2c1c3ccc(F)cc3)C4CC4)CC(=O)O,.91 | |
| Nc1cccc2c3ccccc3C(=O)C(=O)c12,2.95 | |
| CC(C)(C)OC(=O)N1CCN(CC1)c2ncc(OCc3ccncc3S(=O)(=O)C)cn2,2.4 | |
| C[C@](O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc(C#N)c(c2)C(F)(F)F,2.87 | |
| CNc1cccc(CCCc2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)n1,.57 | |
| O=C(NCc1ccncc1)c2ccc(Oc3ccccc3)cc2,3.26 | |
| OC(=O)COc1ccc(Cl)cc1CN2CCN(CC2)S(=O)(=O)Cc3ccccc3,.33 | |
| C[C@@H](NC(=O)C1CCNCC1)c2ccc(Nc3ncc4cc(ccc4n3)c5ccncc5)cc2,.4 | |
| CN(C)C[C@H](O)Cc1ccc(Cl)c(c1)C(=O)NCC23CC4CC(CC(C4)C2)C3,2.19 | |
| Oc1ccnc2ccccc12,.8 | |
| CN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1,4.31 | |
| COc1cc(Nc2cc(Oc3ccc(C)nc3)ccn2)cc(OC)c1OC,3.21 | |
| CC1=NC(C)(N=C1N)c2cccc(c2)c3cccnc3,1.7 | |
| COc1cc(F)ccc1c2cc(CNC3CCCC3)ccn2,1.71 | |
| NC(=N)Nc1oc2ccccc2n1,1.91 | |
| Cc1nc2nc(NC(=O)c3ccc(F)cc3)nn2c(O)c1Cc4ccccc4,2.2 | |
| CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccc(Cl)cc2)(c3ccccc3)c4ccccc4,3.47 | |
| CN(C)CCCOc1nccc(Nc2cc(NC(=O)c3ccnc(c3)N4CCOCC4)ccc2C)n1,1.3 | |
| NNC(=O)c1ccncc1,-.57 | |
| CCS(=O)(=O)c1ccc(cc1)c2cc(Cl)ccc2OCC(=O)O,-.78 | |
| Cn1cc(cc1c2c3C(=O)N(CC#C)C(=O)N(CC4CC4)c3nn2Cc5ccnc6ccc(Cl)cc56)C#N,3.96 | |
| COc1cc(Nc2nc(N[C@@H](C)c3ncc(F)cn3)nc(N4CCOCC4)c2F)n[nH]1,2.64 | |
| Cc1cccc(Nc2ncnc3ccccc23)c1,3.21 | |
| OCCCNCCCOc1ccc(Cl)c(c1)C(=O)NCC23CC4CC(CC(C4)C2)C3,1.41 | |
| CCOC(=O)c1ccc(OCCC2(CCN(CC2)c3ccc(C)nn3)C#N)cc1,3.54 | |
| C[C@H]1C[C@H]2[C@@H]3CC[C@H](C(=O)C)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]4(C)CCC(=O)C=C14,3.25 | |
| Fc1ccc(cc1)C(=O)C2CCN(CC2)C(=O)N3CCOCC3,1.61 | |
| Cc1cc(Cl)ccc1N2CCN(CC2)C(=O)COCc3ccncc3,3.22 | |
| CC1CN(CCN1)C(=O)c2cc3ccccc3[nH]2,.94 | |
| Clc1ccc(cc1)C2(CCNCC2)c3ccc(cc3)c4cn[nH]c4,1.51 | |
| Cc1cc(C)cc(c1)c2c(O)nc3cc(Cl)c(cc3c2OCCC4CCCCN4)C(=O)Nc5ccncn5,1.7 | |
| Clc1cccc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1Cl,4.37 | |
| CCOc1ccc(cc1)c2cnc3CCCCCn23,3.01 | |
| CNc1c(Br)cnc2[nH]c(nc12)c3ccnc(N)c3,2.83 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4ccccn34)N5CCN(CC5)C(=O)C,3.65 | |
| FC(F)(F)c1ccc(NC(=O)N2CCN(C[C@@H]3CCCN(C3)C4CC4)CC2)cc1Cl,4.06 | |
| OCC(O)COC(=O)c1ccccc1Nc2ccnc3cc(Cl)ccc23,3.5 | |
| CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@H]2CC[C@H](NC(=O)c3cccc4ccccc34)[C@@H]12)C(C)(C)C,1.94 | |
| COc1cc(F)ccc1c2cccc(CNC3CCCC3)c2,2.29 | |
| COc1cc(ccc1NC(=O)CN2CCOCC2)c3cccc4C(=O)C=C(Oc34)N5CCOCC5,2.3 | |
| CCOc1cc(ccc1NC(=O)CN2CCOCC2)c3cccc4C(=O)C=C(Oc34)N5CCOCC5,2.8 | |
| C1CN2CCC1C(C2)c3ccc(cc3)c4ccccc4,1.76 | |
| Cc1cc(NC(=O)c2oc(Nc3ccccc3F)nn2)ccc1N4CCOCC4,4 | |
| Nc1ccc(cc1)S(=O)(=O)Nc2ccccn2,-.01 | |
| Fc1ccc(CC2=NNC(=O)c3ccccc23)cc1C(=O)N4CCN(CC4)C(=O)C5CCOC5,.8 | |
| CCNC(=O)c1cc2c(c(cnc2[nH]1)c3cnc(OC)c(c3)C4=NNC(=O)O4)n5ccc(n5)C(F)(F)F,2.32 | |
| Clc1cc(Cl)c2c3C(=O)NNC(=O)c3[nH]c2c1,1.02 | |
| CCCCC(NC(=O)CC1CCN(Cc2ccn(c2)c3ccc(cc3)C(F)(F)F)CC1)C4=CNC(=O)C=C4,2.89 | |
| Fc1cccc(Nc2oc(nn2)C(=O)Nc3ccc(nc3)N4CCOCC4)c1,3.2 | |
| CN(C)CC(O)COc1ccc(Nc2nccc(Nc3cc(C)ccc3F)n2)cc1,2.1 | |
| O=C(NC1CC1)c2cc(on2)c3cccs3,2.54 | |
| CCOc1ccc(NC(=O)CCc2c(C)nc3nc(C)nn3c2C)cc1,2.1 | |
| CNc1c(Br)cnc2[nH]c(nc12)c3cccc(N)c3,2.96 | |
| Nc1nc(N)nc(n1)c2ccc(Cl)cc2,2.12 | |
| COc1cc(c2nc(cc(n2)C3(CC3)S(=O)(=O)C)N4CCOCC4)c5cc[nH]c5c1,2.4 | |
| CN(C1CCCCC1)C(=O)c2c(C)nn(c2NS(=O)(=O)c3ccc(C)cc3)c4ccccc4,1.69 | |
| CN(C)CCC[C@]1(OCc2cc(ccc12)C#N)c3ccc(F)cc3,1.48 | |
| COc1ccc(Nc2cc(Nc3ccc(OCC(O)CN(C)C)cc3)ncn2)cc1,1.5 | |
| CC(C)S(=O)(=O)NCC(C)c1ccc(cc1)c2ccc(cc2)C#N,3.5 | |
| O=C(CSc1ccccc1)N2CCN(CC2)C(=O)c3occc3,1.6 | |
| NC1=NC2(CCN(CC2)C(=O)c3ccc(cc3)C#N)Nc4c(F)ccc(F)c14,.86 | |
| CCN1CCCC1CNC(=O)c2cc(ccc2OC)S(=O)(=O)N,-1.2 | |
| CNC1=Nc2ccc(Cl)cc2C(=[N+]([O-])C1)c3ccccc3,2.41 | |
| CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)c2cc3ccsc3[nH]2,3.1 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CN=C1c2cc(F)cc(F)c2)N)C(=O)C(F)(F)F,1.38 | |
| CC(C)N(C(C)C)c1nnc(N)s1,1.49 | |
| CS(=O)(=O)c1ccc(CC(=O)N(C2CC2)C3CCN(CCC(c4ccccc4)c5ccccc5)CC3)cc1,2.89 | |
| Nc1ccc(OCc2ccccc2)cc1,2.2 | |
| NNCCc1ccccc1,-.01 | |
| CCN(C1CCN(CCC(c2ccccc2)c3ccccc3)CC1)C(=O)NCc4ccc(F)cc4,3.9 | |
| Nc1n[nH]c2ncc3CCCCCCc3c12,2.54 | |
| C[C@@H](NC(=O)[C@H]1CCCNC1)c2ccc(Nc3ncc4cc(ccc4n3)c5ccncc5)cc2,1.69 | |
| Cc1c(Sc2ccc(Cl)cc2)c3c(C#N)c(Cl)ccc3n1CC(=O)O,1.6 | |
| CC1(C)NC(=O)N(C1=O)c2ccc(c(c2)C(F)(F)F)[N+](=O)[O-],1.74 | |
| NS(=O)(=O)c1ccc2NC(C3CC=CC3c2c1)c4cccc5ccccc45,1.9 | |
| CC[C@H](NC(=O)c1c([S+](C)[O-])c(nc2ccccc12)c3ccccc3)c4ccccc4,3.17 | |
| Cc1ccnc(NCc2ccccc2O)c1,3.35 | |
| CC(C)c1onc(n1)N2CCN([C@H](C)C2)c3ncc(OCc4ccncc4C#N)cn3,3.3 | |
| O[C@@H](CNCCCSCCOCCc1cccc2ccccc12)c3ccc(O)c4NC(=O)Sc34,3.12 | |
| COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4ccccn34)N5CCN(CCS(=O)(=O)C)CC5,3.1 | |
| COc1ccc(cc1)c2nc(N)s[n+]2c3ccccc3,2.19 | |
| O=C1NC(=O)C(Cc2ccc3ccccc3c2)S1,2.41 | |
| Cc1ccc(cc1NC(=O)c2ccc(OCc3ccccn3)cc2)c4cn(C)cn4,2.54 | |
| O=C(CN1CCOCC1)Nc2ccc(cc2OCC3CC3)c4cccc5C(=O)C=C(Oc45)N6CCOCC6,3.3 | |
| c1ccc(cc1)c2[nH]nc3ccccc23,3.79 | |
| CC(O)(C(=O)Nc1ccc(cc1)S(=O)(=O)c2cccnc2)C(F)(F)F,2.08 | |
| CCCCC(N1NC(=O)c2nc3cc(Cl)ccc3c(O)c2C1=O)c4ccncc4,1.4 | |
| OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N4CCC[C@H]4C#N,-.48 | |
| CCOc1ccccc1N2CCN(Cc3c[nH]nc3c4ccc(F)cc4)CC2,3.38 | |
| COC(=O)Nc1nc2ccc(cc2[nH]1)C(=O)c3ccccc3,2.9 | |
| Fc1cc(ccc1C2=CCS(=O)(=O)CC2)N3C[C@H](Cn4nncc4F)OC3=O,3.54 | |
| C[C@@H]1CC[C@H](CC1)Oc2nc(N)c3ncn([C@@H]4O[C@H](C)[C@@H](O)[C@H]4O)c3n2,2.35 | |
| CC(C)CN1C(=O)N(C)C(=O)c2c1sc(Cc3ccnc4ccccc34)c2C(=O)N5CC[C@@H](O)C5,1.65 | |
| CC(=O)C1=Cc2ccc(O)cc2OC1=O,.87 | |
| C[C@@](O)(C(=O)Nc1ccc(cc1Cl)S(=O)(=O)NCCN2CCOCC2)C(F)(F)F,2.14 | |
| [O-][N+](=O)c1cccc2C(=O)C(=O)c3ccccc3c12,2.6 | |
| CC(=O)N[C@@H]1CC2(CCN(Cc3ccc4[nH]c5ccccc5c4c3)CC2)c6ccccc16,2.96 | |
| CC(C)(C)C(=O)N[C@H]1CCCCNC1=O,.58 | |
| Oc1cc(ccc1NC(=O)CN2CCOCC2)c3cccc4C(=O)C=C(Oc34)N5CCOCC5,2.4 | |
| CCCSc1c(cnn1c2ccc(cc2)C(=O)O)C(=O)NC3CCCCC3,.64 | |
| Cc1ccc(cc1)c2c[nH]nn2,2.58 | |
| CCCCOc1nc(N)c2NC(=O)N(Cc3cccc(CC(=O)O)c3)c2n1,.14 | |
| O=S(=O)(Nc1cccc2[nH]ncc12)c3cccs3,1.7 | |
| COc1cc(OC)c(cc1NC(=O)C)S(=O)(=O)NCc2ccccc2N3CCC(CO)CC3,1.03 | |
| COCCNCc1ccc(cc1)c2cc(C(=O)N)c(NC(=O)N)s2,.87 | |
| C[C@H](NC(=O)c1c(C)nn(C2CCCCC2)c1NS(=O)(=O)c3ccc(C)cc3)C(C)(C)C,1.97 | |
| CC(C)N1CCC[C@H](CN2C(=Nc3ccc(Oc4ccc(F)cc4)cc3C2=O)C)C1,2.4 | |
| Nc1ccc2cn[nH]c2c1,.52 | |
| Cc1cc(n[nH]1)c2ccc(Cl)c(c2)C(=O)NCC3(O)CCCCCC3,3.41 | |
| Nc1ccc(cn1)C(=O)Nc2cccc(c2)c3nc(N4CCOCC4)c5oc6ncccc6c5n3,3.44 | |
| Fc1ccc(CNC(=O)CCS(=O)(=O)c2ccc(Br)cc2)cc1,3.1 | |
| CC1(CC(=O)NC(=N1)N)c2ccccc2,.62 | |
| CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)c2cc3ccccc3[nH]2,3.4 | |
| C[C@H](Nc1cncc(Nc2ncc(C)s2)n1)c3ncc(F)cn3,1.91 | |
| Cc1ccc(Oc2ccc(Nc3ncnc4[nH]nc(OCCN5CCC(O)CC5)c34)cc2Cl)cn1,3.4 | |
| OC(=O)c1ccc(cc1)N2CCC(CN3CCC(CC3)Oc4ccc(Cl)c(Cl)c4)CC2,2.31 | |
| COc1ccc(cc1N2CC(=O)NS2(=O)=O)c3ccccc3,-1.01 | |
| CCOc1ccccc1CNCc2cccc(CCNC[C@H](O)c3ccc(O)c4NC(=O)Sc34)c2,1.13 | |
| CCCCNc1cc(cc(c1Oc2ccccc2)S(=O)(=O)N)C(=O)O,-.3 | |
| OC(=O)COc1ccc(cc1c2ccccc2c3ccccc3)C(F)(F)F,1.38 | |
| Cc1nc(cs1)C(=O)N2CCCC3(CCN(Cc4ccc(Cl)cc4)CC3)C2,.64 | |
| COc1cc(Nc2nc3c(cc2F)ncn3[C@@H](CO)c4ccc(F)cn4)n[nH]1,2.18 | |
| CC1(CCN(CC1)C(=O)COCc2ccncc2)c3ccc(Cl)cc3,2.79 | |
| NC1(CCN(CC1)c2ncnc3[nH]ccc23)C(=O)NC(CO)c4ccc(Cl)cc4,2.4 | |
| CNC(=O)c1cccc(c1c2ccc(CC(C)C)cc2)S(=O)(=O)Nc3ncc(C)nc3OC,1.68 | |
| Oc1ccc(cc1)[N+](=O)[O-],1.5 | |
| CCC(CC)NC(=O)c1cnn(Cc2ccccc2)c1NS(=O)(=O)c3ccc(C)cc3,1.52 | |
| Oc1cccc2Oc3ccccc3C(=O)c12,3.8 | |
| COc1cc2c(Nc3cc(CC(=O)Nc4cccc(F)c4F)[nH]n3)ncnc2cc1OCCCN(CCO)CC(C)C,3.61 | |
| COc1cc2c(Nc3c(Cl)ccc4OCOc34)ncnc2cc1OCCCN5CCCCC5,2.05 | |
| COc1cc2ncnc(Oc3cnn(CC(=O)Nc4ccc(cn4)N(C)C)c3)c2cc1OC,2.36 | |
| C(Cn1c2CCCCc2c3c(nc(nc13)N4CCCC4)N5CCCC5)N6CCOCC6,3.6 | |
| CC(C)(C)OC(=O)N1CCN(CC1)c2ncc(OCc3ccc(cc3)S(=O)(=O)C)nn2,2.93 | |
| CC(C)C(NC(=O)CN1C(=O)C(=CN=C1c2cccs2)N)C(=O)C(F)(F)F,.68 | |
| Cc1ccnc2nc(nn12)C(=O)Nc3nccs3,.31 | |
| OC(=O)[C@H](Cc1ccc(cc1)N2CCN(CC2)c3ccccc3)NC(=O)c4c(Cl)cccc4Cl,.08 | |
| CCNC(=O)Nc1nc2cc(ccc2[nH]1)c3cccnc3,2.34 | |
| CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(=O)(=O)O,2.93 | |
| CN1CCCC1CCOC(C)(c2ccccc2)c3ccc(Cl)cc3,3.04 | |
| NC1=NC(CC(=O)N1)c2ccc(Cl)c(Cl)c2,1.46 | |
| Oc1c(C#N)c(nc2ccncc12)c3ccc(cc3)c4ccccc4OC(F)(F)F,3.45 | |
| NCC(O)(c1ccc(Cl)cc1)c2ccc(Cl)cc2,2.69 | |
| Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1,-.51 | |
| O[C@@H](CNCCOCCCNCCc1cccc(Cl)c1)c2ccc(O)c3NC(=O)Sc23,.83 | |
| CN1CCC[C@@H]([C@H]1C(=O)Nc2ccc(OCc3cc(C)nc4ccccc34)cc2)C(=O)NO,2.41 | |
| COC(=O)COc1ccc(cn1)C(=O)Nc2ccc(F)cc2,2.43 | |
| CCC(N1NC(=O)c2nc3cc(Cl)ccc3c(O)c2C1=O)c4ccccn4,.8 | |
| Cc1cccc(Nc2oc(nn2)C(=O)Nc3ccc(nc3)N4CCOCC4)c1,3.42 | |
| CCOC(=O)c1ccc(OCC2CN(C2)c3ccc(C)nn3)cc1,3.1 | |
| COc1cc(F)ccc1c2cncc(CNC3CCCCC3)c2,2.6 | |
| Oc1cccc(NC(=O)c2ccc(OCCCN3CCCC3)cc2OCc4ccccn4)c1,1.78 | |
| CC1CC(N(C(=O)C)c2ccccc2)c3ccccc3N1S(=O)(=O)c4ccccc4,3.68 | |
| OCCc1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1,3.85 | |
| CCN(C1CCN(CCC(c2ccc(F)cc2)c3ccc(F)cc3)CC1)C(=O)Cc4ccc(cc4)S(=O)(=O)C,3.21 | |
| COc1cccc2[nH]ncc12,2.1 | |
| Clc1ccc2ncccc2c1C(=O)NCC3CCCCC3,2.65 | |
| CN1C(=O)C=C(CCc2ccc3ccccc3c2)N=C1N,2.7 | |