Co-administration of a single 100 mg oral dose of sitagliptin and a single 600 mg oral dose of cyclosporine increased the AUC and Cmax of sitagliptin by approximately 29% and 68%, respectively.
Kun 100 mg sitagliptiinia ja 600 mg siklosporiinia annettiin samanaikaisesti kerta- annoksina suun kautta, suureni sitagliptiinin AUC- arvo noin 29% ja Cmax- arvo noin 68%.