Furthermore, irbesartan induced hyperplasia/ hypertrophy of the juxtaglomerular cells (in rats at ≥ 90 mg/ kg/ day, in macaques at ≥ 10 mg/ kg/ day).
Irbesartaani aiheutti edelleen jukstaglomerulaarisolujen hyperplasiaa/ hypertrofiaa (rotilla ε 90 mg/ kg/ vrk, makakeilla ε 10 mg/ kg/ vrk).