Severe hypoglycaemic episodes, where the patient has become unconscious, can be treated by glucagon (0.5 to 1 mg) given intramuscularly or subcutaneously by a person who has received appropriate instruction, or by glucose given intravenously by a medical professional.
Vaikeat hypoglykemiakohtaukset, joissa potilas on tajuton, voidaan hoitaa antamalla glukagonia (0, 5- 1 mg) lihakseen tai ihon alle (tarpeellisen koulutuksen saaneen henkilön toimesta) tai glukoosia laskimoon (terveydenhoitohenkilön toimesta).