In circumstances where exposure to HBV has recently occurred (eg needlestick with contaminated needle) the first dose of ENGERIX B can be administered simultaneously with HBIg which however must be given at a separate injection site.
Mikäli henkilö on altistunut hiljattain hepatiitti B - virukselle (esim. saastuneen neulan pisto), ensimmäinen ENGERIX B - annos voidaan antaa samanaikaisesti HBIg- annoksen kanssa mutta eri injektiokohtaan.