Following concomitant administration of carbamazepine, a potent inducer of CYP3A4, the geometric means of Cmax and AUC for aripiprazole were 68% and 73% lower, respectively, compared to when aripiprazole (30 mg) was administered alone.
Kun voimakasta CYP3A4: n induktoria, karbamatsepiinia, annettiin samanaikaisesti, aripipratsolin Cmax - arvon geometrinen keskiarvo oli 68% pienempi ja AUC- arvon geometrinen keskiarvo 73% pienempi kuin annettaessa aripipratsolia (30 mg) yksinään.