At this time, in imitation of Saint Catherine of Genoa (1477-1510), Virginia began to send her older girls to care for the sick at Pammatone Hospital. Later on, during an epidemic in 1656-1657, fifty-three of them would die victims of their own charity.
Un tiempo después, a causa de una epidemia, en 1656-1657, cincuenta y tres de ellas morirán víctimas de su dedicación.