Additional in vitro studies in rat and human hepatocytes showed that ambrisentan did not inhibit sodium-taurocholate co-transporter (NTCP), organic anion export pump (OATP), bile salt export pump (BSEP) and multi-drug resistance protein isoform-2 (MRP2).
Estudios adicionales in vitro en ratas y hepatocitos humanos mostraron que ambrisentan no inhibe el co-transportador de sodio-taurocolato (NTCP), la bomba transportadora de aniones orgánicos (OATP), la bomba exportadora de sales biliares (BSEP), ni la proteína isomorfa-2 asociada a resistencia a multifármacos (MRP2).