(c) potential environmental transformations and metabolic alterations of the substance, as these changes may lead to the production of chemicals with greater toxicity persistence in the environment, particularly if the substance is not biodegradable and is able to accumulate in humans, the environment or food chains;
(c) ukuba nokutshintshwa kwemeko yezendalo nokuguquka kwemeko yesingcolisimoya, njengoko ezi nguqu zinokukhokhelela ekuvelisweni kwemichiza eyityhefu kakhulu kokusingqongileyo, ngokukodwa ukuba ezo zinto ngokukodwa ukuba lo nto inokuboliswa ziintsholongwane kwaye inakho ukuphinda-phindeka, kokusingqongileyo okanye kuthungelwano lomjikelo wokutya;