Some are visible at birth (e.g. Down syndrome, cleft-lip, club foot); others are not immediately obvious and only manifest themselves later on in life (e.g. diabetes, porphyria).
Ezinye zibonakala xa ezalwa umntwana (umz. iDown syndrome, i-cleft-lip, unyawo olusisilima); ezinye azicaci ngokukhawuleza zize ziziveze ngokuya ekhula umntwana (umz.isifo seswekile, i-porphyria).