Progesterone creams cannot provide a high enough level of protection of the lining of the uterus, so they are unsafe when used to balance out a "natural" estrogen.
Iikhrim zeprogesterone aziyikhuseli ngokwaneleyo inwebu yesibeleko ngoko ke azikhuselekanga ukuba zingasetyenziselwa ukulinganisa i-estrogen "yendalo".