Fertilization is accomplished by exposing the eggs to sperm in a culture dish, or by directly injecting a single sperm into each mature egg (intracytoplasmic sperm injection - ICSI).
Ukuqhama kuphumelela ngokubhentsisa amaqanda kumadlozo kwisitya sokukhulisela, okanye ngokufaka idlozi elinye ngesitofu ngqo kwiqanda ngalinye elivuthiweyo (ukufakelwa kwedlozi ngesitofu eqandeni elivuthiweyo - ICSI).