The other powerful anti-estrogen treatments for breast cancer, like letrozole (Femara® ), which are often started after 5 years of tamoxifen treatment, can decrease bone density significantly, though.
Amanye amayeza asetyenziselwa ukunyanga umhlaza webele nalwa ne-estrogen afana ne-letrozole (Femara® ), aqalwa ukusetyenziswa emva kweminyaka emihlanu ufumana unyango lwe-tamoxifen ayabuhlisa ngamandla ubunzima bamathambo.