You may discuss with his physician to titrate up (increase) his methotrexate (if possible) vs. a consideration to change from an oral to a subcutaneous route of administration to improve bioavailability and thus effectiveness of the methotrexate.
Kuya kufuneka uthethe nogqirha wakhe nibonisane ngokunyusa ithamo lakhe le-methotrexate (xa kunokwenzeka oku) okanye ngokugqala ukutshintsha unyango lomlomo afumane olufakwa ngaphantsi kolusu ukuphucula ukungena kweyeza elitsha emzimbeni nokusebenza kwalo kuze kananjalo kuphucuke ukusebenza kwe-methotrexate.