This occurs as a result of inadequate or irregular management of "ordinary" TB, either by using inappropriate drug combinations or by using single drugs for "ordinary" TB, clinics running out of drug stocks, inadequate counseling of patients leading to patients not taking their treatment correctly (poor treatment compliance) or patients not returning for treatment (defaulting treatment).
Oku kubangelwa lulawulo lweTB “eqhelekileyo” olunganelanga okanye olungafanelekanga, ngokusebenzisa imidibaniso yamachiza engafanelekanga okanye ngokusebenzisa amachiza amanye eTB “eqhelekileyo, ukuphelelwa kweekliniki ngamayeza, ukungacetyiswa kwezigulana ngokukuko okukhokelela ekubeni zingawaseli ngokukuko amayeza (ukusilela ukuthobela unyango) okanye izigulana ezingabuyeliyo ukuyolanda amayeza (ukusilela ukusebenzisa amayeza).