Most MDR TB will develop as a result of poor adherence to the treatment for "ordinary" TB. However it is possible for someone who has never had or been treated for TB before to be infected with bacteria that are already resistant to ordinary TB drugs, if they have had close contact with someone with MDR TB.
I-MDR TB ibangelwa kukungawaseli ngokukuko amayeza eTB “eqhelekileyo”. Kodwa kuyenzeka ukuba ubani ongakhange anyangelwe iTB ngaphambili osulelwe yintsholongwane exhathisayo kunyango lwamachiza eTB aqhelekileyo, xa ethe wasondelana kakhulu nomntu oneMDR TB.