Current therapies including diet, exercise, behavior modifications, oral diabetes agents, and insulin, are employed to control Type 2 Diabetes mellitus (T2DM), but rarely return subjects to euglycemia, require dose escalation over time and can be associated with hypoglycemia and weight gain. Obesity is a well-established risk for both the development of diabetes as well as for increased mortality. The majority of individuals with T2DM are overweight or obese. Obesity and type 2 diabetes mellitus are common and well documented risk factors for non-alcoholic fatty liver disease (NAFLD). For some patients NAFLD disease is a relatively benign condition, for others NAFLD will progress to cirrhosis and end-stage liver disease with associated complications including hepatocellular carcino.The current treatment for NAFLD and nonalcoholic steatohepatitis (NASH) is weight reduction which can be achieved by life style modifications, drug therapy or bariatric surgery. The Fibro Test and Fibro Max have proven their efficacy as noninvasive biomarkers for NAFLD and NASH in large scale studies. Transient Elastography which measures liver stiffness non-invasively has been successful in identifying fibrosis in NAFLD.