- If participating in sexual activity that could lead to pregnancy, the participant (men and women) with HCV genotype 1a infection who will receive RBV must agree to use two reliable methods of contraception simultaneously while receiving study treatment and for 6 months after stopping study treatment and participants (men and women) with HCV genotype 1b infection who will not receive RBV must agree to use two reliable methods of contraception simultaneously while receiving study treatment and for 30 days after stopping study treatment. A combination of TWO of the following contraceptives MUST be used appropriately: