Several therapeutic interventions are currently used to try to aid in the recovery of upper limb functioning. There is limited evidence that hands-on therapy, including passive joint mobilization, manual stretching of soft tissue and passive exercises, is effective. Strength training in chronic stroke may reduce motor impairments in patients with mild-moderate paresis, but without any effect on ADL-performance. Likewise, there is limited evidence for the use of mirror therapy, sensorimotor and mental training. The evidence for using orthoses and other supporting devices is inconclusive. Repetitive task-oriented practice, which is probably the widest used intervention in facilitating upper limb recovery after stroke, has demonstrated promising results mostly in chronic stroke when delivered using virtual reality systems and robots, as well as constrained-induced movement therapy. However, these approaches are patient and resource demanding in terms of hours of daily training or expensive technologies. Moreover, it remains unknown if the functional benefits persist at long-term.