Along with insulin resistance, obesity is associated with a specific dyslipidemia including hypertriglyceridemia, low high-density lipoprotein (HDL) cholesterol and small dense and oxidized low-density lipoprotein (LDL) cholesterol.42-44 Weight reduction leads to significant improvements in hypertriglyceridemia.30 We anticipate that mindfulness will similarly improve lipid profiles. In order to see a statistically significant reduction in triglyceride levels of approximately 30%, given the medium to large effect sizes seen in the literature, requires a sample size of 40 with 20 in each group.33,34