We expect to enroll all participants within 24 months and evaluate the study 12 months thereafter. Participants will continue with azacitidine until disease progression, and with vaccination for up to 2 years, or until disease progression. Participants may stop treatment at any time upon their own request, or will be withdrawn from treatment following disease progression or severe toxicity during treatment. The inclusion period is expected to begin in April 2016 and to be finalized in April 2018. Thereafter a follow-up period of maximum 2 years is following. Last participant last protocolled visit date will be at latest, April 2020.