Impairments in higher level cognitive processing, such as new learning and memory, are among the most common deficits in individuals with Multiple Sclerosis (MS) and such deficits have been shown to exert significant negative impact on multiple aspects of everyday life, including occupational and social functioning. Despite these findings, few studies have attempted to remediate these cognitive deficits in order to improve the everyday functioning of individuals with MS. While limited research addressing the efficacy of memory retraining in MS does exist, this research has been marred by significant methodological flaws. Specifically, the only existing study of memory retraining in MS to utilize: (1) a randomized clinical trial and (2) an objective outcome assessment is our pilot research carried out at Kessler Medical Rehabilitation Research and Education Corporation (KMRREC).