- Iron administration: Iron saccharate (Venofer) will be administered i.v. at the dose of 200 mg (2 vials of Venofer) on days 28, 42, and 56 after the transplant. Venofer will be diluted in 250 ml saline and infused over 60 minutes. Iron will be omitted in patients with severe iron overload (serum ferritin > 2500 µg/L in the absence of inflammation or liver necrosis) or elevated transferrin saturation (TS > 60%) between days 21 and 56. No iron supplementation will be allowed in arm 1. No iron supplementation will be allowed in arm 2 before day 70 after the transplant. In arms 2 and 3, if patients have evidence of functional iron deficiency (Transferrin saturation < 20%) on day 70 or later, they may receive 300 mg of Venofer over 90 min, for a minimum of 2 doses.