6. Adequate organ function: ANC >/=1,500 /mcL, Platelets >/=100,000/mcL, Hgb >/=9 g/dL or >/=5.6 mmol/L w/o transfusion within 7 days of assessment, creatinine OR calculated creatinine clearance </=1.5 X upper limit of normal (ULN) OR >/=60 mL/min for subject with creatinine levels >1.5 X institutional ULN, total bili </=1.5 X ULN OR Direct bilirubin </=ULN for subjects with total bili levels >1.5 ULN AST (SGOT) and ALT (SGPT) </=2.5 X ULN OR </=5 X ULN for subjects with liver metastases Albumin >2.5 mg/dL Coagulation International Normalized Ratio (INR) or Prothrombin Time (PT) Activated Partial Thromboplastin Time (aPTT) </= 1.5 X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants </= 1.5 X ULN unless subject is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants aCreatinine clearance should be calculated per institutional standard.