De Smet et al presented their experience with a case of 48-year old male, with nephrotic syndrome secondary to FSGS, treated with oral galactose at 10 gm BID for 6 months, at the annual meeting of American Society of Nephrology 2008 (ASN 08, TH-PO-955). Their patient had failed to respond to prednisone, cyclophosphamide, mycophenolate mofetil, cyclosporine and plasma exchanges. Prior to treatment, the FSPF was detected at 0.87 and urinary protein excretion was 4.3 gm/day. After treatment with galactose, the FSPF decreased to 0.09 and urinary protein excretion decreased to 0.56 gm/day. The success obtained in this case argues for trial in additional patients.