The screening procedure will consist of obtaining an extensive medical history (including disease history, current medical conditions and use of medication, substance use, employment, education, family history, self-reported birth weight), complete physical examination, drawing blood for hematologic and biochemistry testing (Full blood count, glucose, HbA1c, creatinine, AST, ALT, gamma-glutamyl transferase (GGT), alkaline phosphatase (ALP) and thyroid-stimulating hormone (TSH)), urine screening, urine creatinine and albumin, and a 12-lead electrocardiogram (ECG).