In addition to evaluation of the effectiveness of the TOS special tests, the effects of Osteopathic manipulative treatment (OMT) to help alleviate TOS symptoms is also of interest. OMT of TOS is directed towards improving mechanics of the cervical, upper thoracic spine, upper ribs, clavicles and muscles of the neck, shoulder and pectoral girdle. OMT procedures such as myofascial release and articulatory techniques can be useful in reducing the dysfunctions of these regions which is causing compression on the nerve. Myofascial release involves manipulating the soft tissues, articulation is taking a joint through its available range of motion to improve its normal physiological movement (Ward, 2003). By performing this research we can improve the body of research in osteopathic manipulative medicine (OMM) and provide a proven means of treating the pain experienced by individuals with TOS.