11. Adequate renal function as evidenced by serum creatinine less than or equal to 1.8 mg/dL (158 umol/L) OR calculated creatinine clearance greater than or equal to 50 mL/min (per the Cockcroft-Gault formula) with less than 2+ protein OR 24- hour urine creatinine clearance greater than or equal to 50 mL/minute with 24- hour urine protein less than 1g.