- Current and past systematic use of topical or systemic antihistamines (2 weeks prior to the Baseline Visit, topical steroids (2 weeks prior to the Baseline Visit), systemic steroids (6 weeks prior to the Baseline Visit), cytotoxic treatment (4 weeks prior to the Baseline Visit), cyclosporin A and other immunosuppressants (8 weeks prior to the Baseline Visit), naltrexone, paroxetine, fluvoxamine, amitriptyline, gabapentin, pregabalin (prescribed for the pruritus treatment, 4 weeks prior to the Baseline Visit), topical calcineurin inhibitors, topical antibiotics, antiseptic bathes and cleansing lotions (8 weeks prior to the Baseline Visit);