Variables: effects of DHA treatment on total cholesterol and its fractions, triglycerides, insulin, fibrinolysis markers, tumor necrosis factor alpha (TNF-α), and fat distribution assessed by anthropometric measurements, bioimpedance, sonography, DEXA and abdominal CT. Effects of DHA administration on phenotype and functional capabilities of dendritic and mononuclear cells. Objective: To determine if treatment with high doses of highly purified docosahexanoic acid (DHA) is able to revert, totally or partly, the lipid disturbances and the fat redistribution associated with highly active antiretroviral therapy (HAART), and the effects on phenotype and function of dendritic cells and monocytes Data analysis: Baseline data will be analyzed for a good balance. Fisher´s exact test will be used to assess differences between categorical variables, Student's t test for continuous variables, and Mann-Whitney test for ordinal variables. The main efficacy variable will be differences between baseline and final values using MANCOVA model taking baseline value as covariable. Efficacy will be assessed by contrasting adjusted means at the end of the study between both groups of treatment. Intention to treat analysis will be used.