2. Clinical evaluation: Smoking history (cigarettes/day, packs-year), date of COPD diagnosis, comorbidities, current medication; visits to primary care physician or pulmonologist (scheduled and unscheduled) and emergency room (date and cause), hospitalizations (date and cause) and periods off work (date and cause); number and date of moderate (prescription of antibiotics or systemic corticosteroids) or severe (hospitalization or stay in the emergency department >24 hours) exacerbations.