Methods: The study will be conducted in Biombo, Oio and Cacheu in Guinea-Bissau, where home visits are not yet implemented. At two-monthly visits by the BHP team all registered pregnant women will be offered to participate in the study. Community key informants will communicate information on births in the village to the BHP study team, and the study nurse will visit every new-born child shortly after a CKI calls, if possible on the same day. Villages will be randomised to receive immediate vaccination of their children shortly after birth or at the first visit by the BHP team.