Methods: The study was characterized as a crossover randomized clinical trial, with a 7 day washout period. The sample was composed of 12 sedentary men, aged between 20 and 40 years. All volunteers who agreed to participate in the study signed a two-way informed consent form (TCLE). The study protocol followed the recommendations of the Helsinki Declaration. Subjects were invited to perform three (3) protocols, in a randomized fashion, with a minimum period of one week interval (washout period). On day 0, they arrived to the laboratory at the end of the day, between 6 and 7pm, to perform 45min of treadmill exercise at 60% of the VO2peak or rest, depending on randomization. Soon after, he received a Standard Meal (SM; 60% carbohydrate, 20% fat, 20% protein) in the laboratory and was instructed to perform a 12-hour fast. On day 1, they arrived at the laboratory between 7 and 8 a.m and were submitted to basal blood collection. Soon after, they received a High Fat Meal (HFM) which consisted of sandwich with cream and cheese, added to the drink rich in FRUCTose (0.5 g / kg) or DEXtrose (isoenergetic). The meals had the same energy and macronutrients (50% fat, 40% carbohydrate and 10% protein) and should be consumed in 10 minutes. Blood samples were collected from 1 to 4 h after the meal consumption to analyze the postprandial parameters. Subsequently the subject was released to perform his daily activities outside the laboratory. On the same day, between 6 pm and 7 pm, the subject returned to the laboratory to remain at rest and receive a SM again and be instructed to perform 12 hours of fasting. On day 2, subjects reached the laboratory between 7 and 8 a.m. and again submitted to baseline blood collection. Soon after, they received HFM with a drink rich in DEXtrose (0.5g / kg). Blood samples were collected from 1 to 4 hours after eating the meal. A 24h food record was done to control subject's diet. Body composition was evaluated before intervention. The data were analyzed using the statistical package IBM SPSS statistics (Statistical Package for Social Sciences) version 20.0 (IBM, USA) for Windows. The distribution of all variables was analyzed using the Shapiro-Wilk test, and the analysis sphericity by the Mauchly test. In cases where the data did not pass the normality tests, the respective nonparametric tests were performed. Data from the experimental groups were treated by two-way ANOVA for repeated measurements (2 x 5). If necessary, the Bonferroni post-hoc was used to identify differences. Incremental and total area under the curve were analyzed by trapezoidal method. The difference between AUC was verified by one-way ANOVA with post-hoc Bonferroni. All results were expressed as mean and standard deviation, or median, where appropriate, and the accepted level of significance was 5%.