Results from a rigorous systematic review, benchmarking, and expert opinion are being used to develop a clinical practice guideline for sensory-based interventions for hospitalized, very preterm infants using the Appraisal of Guidelines for Research and Evaluation II instrument. The manualized intervention, from the integrative review and development of the implementation plan, set to be completed by November 2015 (funding from the University Research Strategic Alliance), will include evidenced-based interventions that can be conducted by parents with their preterm infants across postmenstrual age while hospitalized (see Appendix 1 for a working model of the intervention plan). The sensory-based intervention will include the provision of specific amounts of auditory, tactile, vestibular, kinesthetic, and visual exposure to be conducted daily through hospitalization. The intervention plan is intended to be implemented by parents (when available), and by surrogates when the parents are unable to be present in the hospital. Surveys and focus groups of a multidisciplinary team of health care professionals and parents of preterm infants in the NICU are being conducted to assess acceptability, appropriateness and feasibility of the sensory-based intervention plan.