The methodology to perform in the centers where the clinical trail will be conducted are the following: After obtaining informed consent, the patient's baseline will be examined with the collection of demographic data, HIV infection status, pharmacological data, anthropometric parameters, and it will proceed to conduct a complementary examination designed to identify and define body fat composition, body fat distribution and to perform a basal analysis including the parameters previously mentioned. It also will be evaluated the hygienic-dietetic habits of the patient with special attention to alcohol intake, physical activity and concomitant medication. This procedure will be carried out by making retrospective diaries from the last 7 days. The patient's daily caloric intake will be quantified by the Nutrilogic ® software (Bio Logic, Barcelona, España). Physical activity will be quantified by the Minnesota scale (Elosua R, Marrugat J, Molina L, Pons S, The MARATHOM Investigators. Validation of the Minnesota leisure time physical activity questionnaire in Spanish men. Am J Epidemiol 1994, 139: 1197-1209).