Both patients already on other statins and statin naïve patients will be recruited. For patients on other statins, a washout period will not be required due to ethical reasons. After providing informed consent, baseline lipid values will be obtained. Study subjects will be initiated on a starting dose of rosuvastatin of 20 mg. Subjects will be followed every six weeks for a 3 month period. A lipid profile and LFT's will be obtained at 6 weeks and 3 months. Patients not at the intensive LDL-C target of <70 mg/dl will be increased to 40 mg, if necessary.