Adequacy of the Sample: We evaluated the effect size difference that could be detected with 80% and 90% power in a pre-post treatment study of galactose involving 10 patients assessed pre-treatment and post-treatment. The correlation between measurements on the same person was assumed to be .7 and the two-tailed type 1 error was set at 0.05. The study will have better than 90% power to detect effect size differences of 0.6 sd and better than 80% power to detect effect size differences of 0.5 sd. These are considered to be moderate effect sizes.