Time 0 is defined as start of infusion. Adverse events will be assessed during the enrolment visit following the infusion and at every visit thereafter. Routine laboratory safety parameters and urine will be collected at screening, immediately post infusion and during the follow up period. ECG and vital signs will be monitored throughout the study, Volunteers will be asked to complete a diary card up to 2 weeks post-injection. Clear instruction will be provided during the immunisation visit.