IV. Determine messenger ribonucleic acid (mRNA) expression levels of genes involved in the Wnt pathway (i.e. survivin) by reverse transcriptase‐polymerase chain reaction (RT‐PCR) in patients treated with mFOLFOX6/bevacizumab and PRI‐724 vs. mFOLFOX6/bevacizumab alone both in circulating tumor cells (CTCs) and tumor biopsy specimens.