Staphylococcus aureus has become the leading pathogen responsible for hospital-acquired pneumonia (HAP) and is responsible for about 20% of cases4. Staphylococcus aureus may be either sensitive or resistant to oxacillin/methicillin. Oxacillin resistance rates are increasing nationwide and the average rate of resistance to oxacillin currently exceeds 52% nationwide5. While these "MRSA" isolates at UK represent only 47% of all staph aureus isolates, rates of methicillin resistant staphylococcus aureus (MRSA) may approach 80% in some institutions (unpublished observation).