Fractional flow reserve (FFR) is a physiologic index for the determination of ischemia-causing coronary stenosis as well as drug eluting stent (DES) optimization, even multiple anatomic imaging parameters have been widely used in clinical practice for the assessment of optimal stent procedure. Prognostic value between post-stent FFR (FFRpost) have been rarely evaluated in patient treated with DES. This multicentre, prospective registry was aimed to evaluate influence of physiologic parameters on the clinical outcome after DES implantation.