Biomedical researchers. The identification of novel genes for FH and other rare lipoprotein disorders has led to a better understanding of metabolic pathways and eventually the potential for novel therapeutic targets. In addition, gene-gene and gene-environment interactions research may shed light on mechanisms of disease. clinical-scientists will have the opportunity to develop investigator-initiated research, using the pan-Canadian registry and biobanking resources as a platform. Researchers in health outcomes and health economics, social, gender and ethnic research will have access to the database in collaboration with provincial administrative databases.