Tissue synchronization can be assessed by the timing of peak systolic motion of different points along the myocardium relative either to the QRS of the electrocardiogram or to the mechanical indicators of systole such as aortic valve opening. Recent advances in software design have now created technology that simultaneously depicts the peak velocities of the entire myocardium viewed in a 2-dimensional echo image. This promotes easy identification of any dysynchronous segments. By subsequently applying discrete cursors to these areas, graphic patterns of both velocity and direction of myocardial motion can be drawn for quantitative analysis. The application of these new sophisticated tools will allow better analysis of electromechanical dysynchrony and may enable definition of criteria, which can be used to identify those patients who will or will not benefit from cardiac resynchronization therapy.