Hematology: Hemoglobin, hematocrit, Red blood count, white blood count, platelets Biochemistry: Serum creatinine, serum urea, serum uric acid, glutamic-oxaloacetic transaminase (GOT), glutamic-pyruvate transaminase (GPT), lactate dehydrogenase (LDH), total cholesterol, low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol (HDL), triglycerides, glycosylated hemoglobin(HbA1c), Creatine kinase (CK), Creatine kinase muscle-brain(CK-MB), high sensitive troponin T hs-TnT, Vascular Endothelial Growth Factor (VEGF), Insulin Growth Factor 1 (IGF-1), hepatocyte Growth Factor (HGF), Stromal Derived Factor 1 alpha (SDF-1 alpha) Urine: Pregnancy test for woman of childbearing potential Coagulation: Prothrombin Time (PT), International Normalised Ratio (INR), activated partial thromboplastin time (aPTT) 4.3.7. Concomitant medications All patients participating in the trial should receive treatment according to evidence based guidelines. Concomitant medications will be recorded throughout the study.