Often or occasionally: Nausea, diarrhea, vomits, dyspepsia, QT-prolongation, elevation of AST, ALT, bilirubin, gamma GT, amylase, leucocytopenia, decrease of prothrombin, eosinophilia, thrombocythemia, thrombocytopenia, anemia, abdominal and head pain, dizziness, dysgeusia; unfrequent: asthenia, candidosis, thoracal and back pain, discomfort, leg pain, anaphylactic reactions, anaphylactic shock, insomnia, vortex, nervousness, tremor, paresthesia, discomposure, depression, hallucination, depersonalization, ataxia, xerostomia, flatulence, obstipation, anorexia, stomatitis, glossitis, tachycardia, edema, hypertension, palpitations, QT-prolongation, syncope, atrial fibrillation, angina pectoris, vasodilatation, hypotension, ventricular arrhythmia, torsade de pointe, hyperglycemia, hyperlipidemia, elevation of prothromin, icterus, arthralgia, myalgia, tendonitis, rash, pruritus, perspiration, urticaria, xerodermia, amblyopia, tinnitus, vaginitis, hepatitis, ataxia, tendon rupture, hypernatremia, hypercalcemia, neutropenia, hemolysis, transient loss of vision.