Posttraumatic Stress Disorder (PTSD) is one of the most prevalent service-related mental health conditions in treatment-seeking Veterans, yet even gold standard interventions are not universally effective. Veterans would be greatly served by development of novel intervention approaches for PTSD, particularly those could be easily transportable. The emerging field of neurotherapeutics, which uses computerized training techniques to modulate cognitive processing, is one such approach that has shown promise for improving cognitive and emotional symptoms in mental health disorders. The current proposal represents the first effectiveness study of a cognitive control training intervention for reducing PTSD symptoms in Veterans, with a goal of exploring neurobiological mechanisms of affective and cognitive generalization of training effects.