Kidney transplantation is the treatment of choice for established stage 5 CKD. Even with correction of uremia, post-transplant MBD is frequent and reflects the pre-existing CKD-MBD, the effects of renal dysfunction after transplantation, and the effects and consequences of immunosuppression. Transplanted patients with CKD-MBD have reduced quality of life and require medical assistance for bone pain, fractures and CV events. Indeed, cardiovascular disease remains the leading cause of death after renal transplantation, still doubling risk of the general population.