Second, we will monitor growth rate using weight, length and head circumference growth. Growth will be compared both to the pre-treatment period and the expected rate of growth. We have established and have guidelines for optimal growth targets and management will be targeted on achieving these rates. We will monitor these carefully. For babies in the NICU or Level 2 nurseries, Dr. Abrams will supervise the nutritional management directly. Infants in the PICU or PCU will be followed by Dr. Carter with the critical care staff. This approach has been in place for the current group of 16 infants and growth has been excellent although final calculations are pending.