Of the 8.6 million new active TB cases that occur annually, the WHO estimates that roughly 3 million of these patients are 'missed' and do not receive the diagnosis or care they need. One of the primary reasons for this gap is delays in accessing TB-related care or long lead times for diagnostic tests. As a result, developing new large scale screening tests (also known as triage or 'rule out' tests) are particularly needed due to the fact that up to 80% of people tested for TB do not have active disease, stretching the limited and valuable resources that are devoted for diagnostic testing. As a result, FIND, a world leader in guiding and coordinating research and development for diseases such as TB, ranked the development of new screening tests as one of the top 3 priorities in the fight against TB.[11]