This multicenter, prospective open registry is designed with the aim of investigating a number of controversial issues regarding current treatment-options and risk factors for the surgical therapy of SAVS with or without CAD. Several studies and information are expected to derive from the data collected in the registry. These data will provide further knowledge on the mechanisms leading to adverse events during or after surgery for SAVS and help their prevention, thus allowing a "tailored" surgical approach for the treatment of this disease.