The first patient will receive a single i.v infusion of syngeneic MSC (2x106 MSCs per kilogram body weight). If the procedure is safe and no major adverse events related to the i.v cell infusion will occur within the first month (early peri-infusion side effects, severe infections possibly due to over-immunosuppression), the second patients will be enrolled. Should the procedure be safe also in this case, the third kidney transplant patient will be enrolled and undergo syngeneic MSC infusion.