After hospital discharge, all study patients will return to the clinical centre for a follow up visit after 30 days. Six months after randomization all the patients will undergo outpatient Cardiac Magnetic Resonance and Conventional Echocardiography. At the same time, all patients will undergo Myocardial Contrast Echocardiography. At 1 year all patients will attend a final site visit at the clinical centers collecting any clinical event. However, all clinical endpoints will be reported as occurring throughout the follow up. Clinical Major adverse cardio-cerebrovascular events (death, myocardial infarction, stroke and re-hospitalization due to heart failure) at 1 year will be adjudicated by a clinical event committee blinded to the patient treatment allocation. This will ensure a consistent and unbiased adjudication of events across all investigational sites.