Delivery Characteristics - Families in settings assigned to intervention will receive ADS as usual in addition to ADS Plus. ADS Plus consists of 5 key components: care management, referral/linkage; disease education; counseling/emotional support/stress reduction, and care skills managing daily challenges and behavioral disturbances (e.g., rejection of care). Each component is tailored to CGs' unmet needs and care context. The intervention begins with two face-to-face sessions with the appointed site interventionist to conduct a systematic needs assessment from which to identify concerns and needs and develop an agreed upon care plan. The interventionist then meets with CGs face-to-face at convenient times (e.g., when relative is brought to or picked up at ADS) to implement the care plan, every other week for the first 3 months, and then for monthly reassessments for newly emerging care concerns thereafter. Contact occurs at a minimum for about 1 hour per month over 12 months (face-to-face/ telephone). Targeted education materials concerning clients' conditions and related matters are shared via email or traditional mail. The goal of each contact is to provide ongoing emotional support, situational counseling, education about importance of taking care of self, referrals/linkages and skills (e.g., stress reduction, behavioral management, how to talk with doctors). The care planning process is collaborative and flexible, reflecting CG fluctuating needs Usual care control group: CGs in the 15 sites assigned to serve as the usual care control group will receive ADS as usual. As the study intent is to demonstrate the added value of ADS Plus, comparing it to ADS (usual care) is appropriate and reflects the translational purpose of the proposed study. Near completion of the study (project year 05), control group sites will have the option of receiving training in ADS Plus for their setting. As CGs in control sites would have completed the study prior to this training, it may benefit these sites and their future clients/families but not those enrolled in the study.