This study will enroll mother-infant pairs into four groups. Infants enrolled in Dose Group 1 and Dose Group 2 will receive a single VRC01 injection less than 72 hours after birth. Infants in Dose Group 3 will receive a VRC01 injection less than 5 days after birth. They will then receive additional VRC01 injections monthly for at least 6 months and no more than 18 months while breastfeeding. Infants will enroll into one of two cohorts in Dose Group 4: Cohort 1 (non-breastfeeding) or Cohort 2 (breastfeeding). Infants in Cohort 1 will receive a single VRC01LS injection less than 72 hours after birth. Infants in Cohort 2 will receive an initial VRC01LS injection less than 5 days after birth, and a second VRC01LS injection at Week 12 if they are still breastfeeding.