Unresolved questions: Consensus definition criteria, specific diagnostic tests, the exact prevalence of this syndrome, and appropriate management strategies are all unresolved questions. To date, there is no single diagnostic test that can identify cirrhotic patients with cardiac dysfunction. Level of natriuretic peptide (proBNP) is elevated due to increased cardiac release and not because of impaired hepatic extraction. Similarly, troponin I was reported to be elevated. The exact role of these markers in the diagnosis of cirrhotic cardiomyopathy, remains to be clarified. We intend to analyze all these markers, in order to describe the existence of pro-inflammatory status, impairment of oxidative stress and presence of myocardial fibrosis. The association between these markers and different parameters of cardiac dysfunction will also be described in our study, for the first time. The optimum management of cirrhotic cardiomyopathy has not been established since there are neither "gold standard" diagnostic criteria nor specific treatments at present. We consider that our research could make progress in this field.