- The statistician conducts all analyses and consult on an ongoing basis throughout the study. Before analysis, continuous variables are subjected to logarithmic transformation. Univariate analyses, followed by selected multivariate analyses, include duration of anesthetic exposure, level of preoperative and postoperative metabolic deficits, as well as coexisting disorders. Bonferroni adjustment is used for multiple comparisons where appropriate. Multiple logitic regression is used to evaluate significant independent predictors of abnormal results.