Since variability is estimated from data from other situations (pre-treatment baseline data), and there is no concrete data on the experimental situation (variability after DHA treatment), it is predefined in this protocol to perform a re-estimation of the sample size when will be obtained a follow up of the 50% after 4 weeks of treatment of the triglycerides values. To this objective data from the main variable, triglyceride levels at baseline and after 4 weeks post-treatment, along with the random assignment but masking the codes will be provided to a second independent statistical group (Catalan Institute of Oncology, Department of Epidemiology and Cancer Registration. Statistician: Dr. Victor Moreno) respect to central statistical analysis of this study (Laboratory of Biostatistics and Epidemiology (LBE), Section Clinical Trials, Autonomous University of Barcelona. Statistician: Dr. Ferran Torres). This new group will perform the analysis, and will only reveal variability data to recalculate the sample size. If the sample size were less than expected, it will be maintained according to the initial design. Under no circumstances significance tests will be performed or the study will be prematurely stopped secondarily to re-estimate variability. According to this method, you do not need any adjustment of multiplicity.