At the screening visit for subjects not taking a statin drug, 13 ml of blood will be drawn. The blood will be processed by the OCTRI Core Laboratory staff. All of the lipid parameters (complete lipid profile, apoB, apoA1, hs-CRP) will be tested at the OHSU lipid core lab. Some of the blood collected will be sent to the OHSU core lab for testing of ALT as well as for obtaining the long-term storage sample. Blood samples will be frozen and stored on the 14th floor of the CHH building in the laboratory of the Oregon State University School of Pharmacy. Samples will be batched for processing (see sample processing below). The lipid profile and ALT from the screening visit will be processed within approximately one week. If necessary laboratory parameters meet inclusion and exclusion criteria, the subject will be scheduled for the first study visit. Encapsulated placebo will be given to the subject to take in between the screening and first study visit.