A prospective, parallel-group randomized control trial was designed. Mustafa Kemal University (MKU) Ethical Board approved the study (B.30.2.MKU.0.01.01.00/255). The exact nature of the study was explained to participants and they were asked to sign a written consent. The tests were carried out at Middle East Technical University Medical Center, Ankara, Turkey between January and June 2008. The independent variables were groups (n=4) and time (n=2). The dependent variable was serum cartilage oligomeric matrix protein (COMP) levels measured at three phases of exercise: before (Recovery), immediately after (Fatigue), and 30-min after the exercise (Regeneration). Participants were subjected to the following tests prior to and at the end of the intervention period: body mass index (BMI), isokinetic leg muscle strength, maximum oxygen consumption (VO2max) and serum COMP levels.