Potential benefits Patients. Patients will have access to expert care in the field of lipoprotein disorders and CVD prevention. In many cases, optimal treatment of severe hypercholesterolemia may be best provided by experts in the field. They will have access to on-going clinical trials and to novel therapies. Furthermore, individual patients will be offered family screening to identify affected members who would benefit from early diagnosis and treatment. The identification of new FH cases by cascade screening proves to be both cost-effective and aligns with the aim of providing personalized medicine for patients with severe lipoprotein disorders.