In addition to this attenuated neurological response, a low chronic inflammation level (particular of obesity) and with the production of cytokines by the proinflammatory adipose tissue there is zinc sequestration at the endoplasmic reticulum and lysosomes of epithelial cells of mammary gland, activating the process of premature recession, compromising the establishment of the copious milk production and causing premature weaning. Another biological alterations that mothers with obesity suffer are that they have an altered glucose management, which compromises their milk production.