2. Measurable disease (at least one measurable lesion) IS required. A measurable lesion is one that can be accurately measured in at least one dimension (longest diameter to be recorded). Each lesion must be > 10 mm when measured by CT scan, MRI, or caliper measurement by clinical exam; or > 20 mm when measured by Chest X-Ray. Lymph nodes must be > 15 mm in short axis when measured by CT or MRI.