Statistical methods Differences between two different groups will be investigated using student's t-test for independent samples and differences between 3 groups will be investigated using Analysis of variance with Bonferroni's post-hoc test. Association between risk factors and future risk of CVD, stroke and diabetes will be investigated using multivariable adjusted Cox regression models. Cox regression models will also be used to investigate changes in the different risk factors during the 5 years of follow up in relation to the later risk of CVD, stroke and diabetes.