Chronic Traumatic Encephalopathy consists of a characteristic neurobehavioral syndrome manifested by failed relationships, marriages, and businesses, emotional disturbances, depression, alcohol and substance abuse, and suicide attempts and completions. It typically begins after a latency period of several years following single or repeated Traumatic Brain Injuries (TBIs). A history of cerebral concussion may or may not be present. The clinical syndrome usually terminates in suicide (6-8). The neuroanatomical correlate consists of a tauopathy, the abnormal staining indicative of tau protein deposition in neuronal cell bodies and their axonal and dendritic connections. These representative changes of neurofibrillary tangles (NFTs) and neuritic threads (NTs) are characteristic of CTE, and distinguish it from other forms of dementia. In addition, white matter changes and inflammation are also seen in these brain specimens (8).