All participants will provide written informed consent. Blood and CSF samples will be analysed also by collaborators in other European countries. Before analysis and sending data and blood/CSF samples to partners of the project, all clinical information and sample information will be made anonymous (coded data). Personal information, i.e., name and personal identity number, is removed from data/samples, and separate codes are given to them before delivering them to other partners for the purposes of the project. Methods for database maintenance and data delivery will be used that have proved to be functional in previous research projects. A formal description of the different data formats, access routines and tools for basic processing will be created at the start of the project.