11. Patients must have adequate: (1) Bone marrow function: Absolute neutrophil count (ANC) >/= 1,500/mcl, equivalent to Common Terminology Criteria (CTCAE v4.03) grade 1; Platelets >/= 100,000/mcl; (2) Renal function: calculated creatinine clearance (Cockcroft-Gault formula) > 50 ml/min OR 24-hour urine creatinine clearance > 50 ml/min; (3) Hepatic function: Bilirubin </= 1.5 x ULN (CTCAE v4.03 grade 1; in patients with known Gilbert Syndrome, a total bilirubin </=3.0 x ULN, with direct bilirubin </= 1.5 x ULN). AST and alkaline phosphatase </= 2.5 x ULN (CTCAE v4.03 grade 1; AST and ALT </= 3 x ULN (or </= 5.0 x ULN if hepatic metastases are present); (4) Neurologic function: Neuropathy (sensory and motor) </= CTCAE v4.03 grade 1; [Continued in Criterion 12]