Treatment with extracorporeal shock waves has been shown to be associated with neovascularization in an animal model. Further, since several shockwave systems have been approved through the PMA process for treatment of chronic proximal plantar fasciitis and chronic lateral epicondylitis, there is a large amount of data regarding the safety of these devices in treating soft tissue. The research done by Meirer et al. (2005) and by Nishida et al. (2004) suggests that local delivery of shockwave therapy results in increased release of growth factors and improved circulation in the wound.