One possible intervention that could be used to decrease CVD risk in RA patients is exercise. Exercise can modify both traditional (e.g. dyslipidemia) and non-traditional (e.g. inflammation) risk factors to decrease the risk of CVD. For patients with cardiac disease, clinical guidelines recommend regular exercise. For this, patients are referred to cardiac rehabilitation (CR) programs, where exercise represents the cornerstone of the program. The goal of these programs is modify CVD risk factors, improve physical capacity and decrease CVD risk. Thus, CR programs may offer a suitable therapeutic intervention to help decrease CVD risk in RA patients. However, RA patients are rarely referred to CR despite their increased risk of CVD. Thus, the effects of CR on inflammation and CVD risk in patients with RA remains unclear.