Comparative analyses will be conducted to determine whether there are statistically significant differences in specific quantitative outcomes between tested and control groups. Because of propensity score matching between tested and control patients, unadjusted comparative analysis will be performed and reported as the primary results. Adjusted analysis using multiple regression models will be used to examine potential confounding effects that cannot be addressed by the matching process. Exploratory analyses will be conducted to explore the impact of YouScript in various subgroups and to identify potential subgroups which will be most likely to benefit from YouScript, as deemed appropriate.