About 2000 nurese aged 40-55 living in peking will be investigated.We will measure the symptoms of perimenopausal syndrome by kupperman index、HRQOL（health -related quality of life) to evaluate the severity of menopausal syndrome and quality of life.We choose nurses whose KMI is above 15 and divided them into intervention group and control group.In intervention group,we give them health education and exercise intervention.