- Target population, in details : all cases which develop neonatal sepsis on mechanically ventilated neonate admitted in NICU.of assiut university children hospital during the period from January 2018 to December 2018 The clinical detection of neonatal sepsis is complicated because of their nonspecific symptoms and indistinctness with the other non-infectious diseases. The initial symptoms of sepsis are nonspecific and require a high degree of speculation for diagnosis.