The photograph will be analyzed using ImageJ software version 1.4.1 ( HYPERLINK "http://rsb.info.nih.gov/ij/docs/intro.html"http://rsb.info.nih.gov/ij/docs/intro.html), a public domain Java image processing program inspired by NIH Image written by Wayne Rasband ( HYPERLINK "mailto:wayne@codon.nih.gov"wayne@codon.nih.gov), Research Services Branch, National Institute of Mental Health, Bethesda, Maryland, USA. The software will be used by an expert PathoLase photo-evaluator to measure the linear distance of non-involved toenail (e.g., clear of infection) immediately before treatment (baseline) and 6 months.