The study will be conducted in Matão, Brazil, a city located in São Paulo state, the wealthiest state in Brazil, in the Brazilian southwest, 300 km northwest to the state capital. According to the 2010 Brazilian census, the Matão population was 76,786 and the estimate for 2017 was 81,878 inhabitants, with no difference in sex distribution . The economy is mainly based on industrial activities and on general services. Ethnicity is diverse, but most people are of Caucasian origin, descendants of European immigrants. The population is urban and stable, with a low rate of interurban migration. About 95% of all dwellings have piped water, a sewage network and electricity.