Pregabalin is absorbed in the small intestine by a saturable transporter (Piyapolrungroj et al. 2001). It is well known that pancreatitis patients suffer from malabsorption of fat and therefore frequently suffer from diarrhea. This could lead to changes in the mucosal surface in the small intestine, and possibly change the absorption of pregabalin. Drug absorption has never been investigated in patients suffering from pancreatitis and the simple and linear kinetics of pregabalin makes it possible to study how drug absorption may vary in these patients. A poorer absorption of drugs could partly explain why pain from pancreatitis is difficult to relieve.