After subjects are positioned in the scanner, the scanner will be shimmed to provide a homogeneous magnetic field for image acquisition. An initial alignment scan is done in 3 orthogonal planes simultaneously using a fast gradient echo sequence developed for the scanner. This scan takes approximately 30 seconds and provides a quick view of the subject's head position. Next, a high-resolution T1-weighted 3-D neuroanatomic scan will be obtained using a inversion recovery, fast spoiled gradient echo (IR-prepped FSPGR) protocol to provide images for morphometric studies, localization of MRS and anatomical localization of the activation maps. The acquisition takes approximately 6 minutes and yields a minimum spatial resolution of 1mm x 1mm x 1.5mm with sufficient signal to noise ratio and contrast between gray and white matter for both manual and semi-automated segmentation of regional brain volumes.