- The following medications are prohibited while the subject is on IMT with Prograf: More than 3 days of continuous dosing with a nonsteroidal antiinflammatory drug (with the exception of aspirin, 75 to 325 mg total daily dose, used for cardiac prophylaxis, which is allowed), azoles, diltiazem, verapamil, nicardipine, rifampin, phenobarbital, phenytoin, carbamazepine, direct factor Xa inhibitors, direct thrombin inhibitors, St. John's wort, and amiodarone.