Cardiovascular diseases are the number 1 cause of death globally and represent a major economic burden on health care systems. The investigators have developed a novel integrated care concept (NICC) which combines telemedicine with intensive support by a call center, an integrated care network including in- and outpatient care providers and guideline therapy for patients with heart failure (HF), atrial fibrillation (AF) or therapy resistant hypertension (TRH). The aim of the study is to show that NICC is preferable over guideline therapy alone. The investigators aim at including approximately 2930 patients who are either inpatients or referred to the outpatient clinic of the participating hospitals by their treating physician. The study will thus inform care providers whether quality of care can be improved by an integrated care concept providing telemedicine through a 24/7 call center approach.