This pilot protocol is designed as a proof-of-concept study to examine whether senescent cells can be induced in response to a cutaneous wound in humans and whether there are differences in the emergence of skin senescent cells between young and old individuals and between different ethnicities. The development of this technique and its standardization is important so that the technique can be used to assess future interventions that may affect cellular senescence, and may be an invaluable method for assessing novel treatments of type 2 diabetes involving senescent cells.