- Fluorescein angiography. The risks of fluorescein angiography include pain from the needle stick; inflammation at the injection site; allergy to the fluorescein dye; feeling of warmth or cold, due to the dye; infection at the site of the needle stick; anaphylactic reaction to the dye; nausea (20% of cases); vomiting (0-7% of cases); headache; hypotension; convulsions; basilar artery ischemia; cardiac arrest; severe shock; or thrombophlebitis at the injection site. Clinical staff are trained to deal with these complications.