The response duration and time to response for responding patients will be assessed using appropriate descriptive statistics. The evaluation of progression-free and overall survival will be carried out using the Kaplan-Meier technique at 1-year follow-up. In the case of progression-free survival, patients whose disease has not progressed will be censored at the date last known to be alive. Similarly, the analysis of overall survival censors patients who are lost to follow-up or who remained alive at the date last known to be alive.