The patients will be fasted for three hours prior to the procedure. An intravenous line will be inserted and intravenous midazolam administered, with the dose titrated to sedative effect; use of sedation, oral or intravenous, for third molar extractions is a common practice in dentistry. Local anaesthetic (2% Lignocaine with adrenaline 1/80000) will be administered at the commencement of the procedure. The paracetamol will be administered as capsules, made by the Pharmacy Dept of the University of Otago 30 minutes prior to the procedure. Dosing will be observed.