The evidence for the clinical effect of pregabalin in neuropathic pain is substantial and is documented in a number of randomized clinical trials (Dworkin et al. 2003, Sabatowski et al. 2004, Rosenstock et al. 2004). The recommended dose for treating neuropatic pain is between 150 mg to 600 mg daily, which is similar to the dose chosen for this study. By the opinion of the principal investigator no clinically relevant medical interactions are described for pregabalin when administered for chronic pancratitis patients.