It is important for the Institutional Review Board Committee to recognize that the actual "clinical trial" part of the study is complete. This IRB proposal is being submitted to perform perhaps the most critical aspect of the study; the data entry of all of the raw data into secure electronic databases, and then the statistical analysis and interpretation - the final step which we feel the patients and their parents are eager to have completed, and one which we hope will have significant impact in the scientific community - advancing the science behind understanding the relationship between asthma and GERD. More importantly, we feel that by completing the objectives of this new concept proposal - analyzing and interpreting the data obtained in the clinical trial, we will prove our hypothesis - that the treatment of GERD in moderate to severe childhood asthmatics will actually help asthma outcomes - thereby demonstrating that childhood is the critical period in which to intervene in modifying and successfully altering the natural history of these two devastating, chronic diseases with life-long morbidity and healthcare impact (i.e. asthma and GERD).