2. METHODOLOGY 2.1 Study Population (Target population of Clinical Trial Subjects) A total of 120 patients with documented Type 2 Diabetes will be enrolled, considering an expected screening failure rate of 30% (n=22) and an expected dropout rate of 8% (n=10), based in previous studies conducted in our center using similar populations and period. We estimate that 88 (44 in each group) subjects will complete all protocol procedures. Per-protocol analysis will be restricted to the participants who fulfill the protocol in terms of the eligibility, interventions and outcome assessment. To be as close to a real life scenario as possible, this clinical trial will include subjects patients who were treated with metformin only and had inadequate glycemic control at the time of enrollment as well as treatment naïve or non-medically treated (e.g., diet) patients.