Our team conducted a 12-week, randomized, double-blind, placebo-controlled clinical trial funded by the Stanley Foundation, to assess the value of 60 mg of raloxifene as adjuvant treatment for the negative symptoms, and other psychotic symptoms, in post-menopausal women. In our study on 33 patients, we found that women in the raloxifene group showed a greater improvement in both positive and negative symptoms, and also in general psychopathological symptoms, than women who had only received antipsychotic medication(28).