- Adequate organ function within 14 days of study registration including: 1) Adequate bone marrow reserve: absolute neutrophil (segmented and bands) count (ANC) ≥1.0 x 10^9/L, absolute lymphocytes ≥400/μL, platelets ≥100 x 10^9/L; hemoglobin ≥ 8 g/dL; 2) Hepatic: - Total bilirubin ≤ 1.5 x upper limit of normal (ULN) and SGPT (ALT) ≤ 2.5 x upper limit of normal (ULN), and 3) Renal: Normal serum creatinine or creatinine clearance ≥60 ml/min/1.73 m^2