Blood samples collected will be used for quantification of over one hundred micro RNA (levels will be assessed) as well as multiple markers of inflammation such as Interleukins 1-36 and their receptors, interferons and their receptors, tumor necrosis factors and their receptors, CCL and CXCL family chemokines and their receptors, macrophage and granulocyte colony stimulating factors and their receptors, and lymphocyte secreted products related to the action of these proteins will be evaluated. No genetic testing will be performed.