- stratification of PWV and AIx dynamics according to different categories The only published reference in the literature is by Takenaka et al (NDT 2005); they showed in a small study that after 6 months of sevelamer treatment PWV decreases from 14.56 m/s to 13.34 m/s i.e. a decrease of approximatively 9% from pre-Sevelamer values. If normalized to BP (PWV divided by corresponding BP level) than PWV/BP decreased from 10.2 m/s/mmHg to 9.3 m/s/mmHg - i.e. again a decrease of approximatively 9% from pre-Sevelamer values.