If the QTcF (QT corrected by Fridericia's formula) value assessed on Day 3 before last dose is above 500 ms, Eurartesim® should be withheld until QTcF returns below 480 ms within 6 hours. Thereafter, the Eurartesim® cycle may be completed under frequent QTc monitoring based on medical judgment. If the QTcF does not return below 480 ms within 6 hours, another antimalarial therapy should be considered.