If genetic testing has not yet been done, blood or cheek cells may be collected to confirm a Batten Disease diagnosis. Blood and cheek samples from participants with Batten Disease and their parents may also be collected and used in an attempt to better understand the genetic changes that cause Batten Disease and influence its severity. Furthermore, female siblings may participate by providing a blood sample. These samples will be examined to see how the amount of estrogen in the blood of females with Batten Disease compares to the amount of estrogen in the blood of their sisters who do not have Batten Disease.