Baseline characteristics of the two groups will be compared with independent t-tests. Descriptive statistics and frequencies will be calculated for all continuous and categorical variables. The Shapiro-Wilk test will be used to test the assumption of normality for all continuous variables. Levene's test will be used to test the homogeneity of variance assumption. The acute effect will be determined by the difference between time points 1) and 2). The chronic effect will be determined by the difference between time points 1) and 3). For each analysis, a time by condition (2 x 2) repeated mixed model ANOVA will be performed. If the interaction effect is not statistically significant, the main effects of time and condition will be explored. An alpha of 0.05 will be used for all analyses. The required sample size is estimated to be 20 participants based on reported global longitudinal strain changes from prior to anthracyclines to post anthracyclines in breast cancer patients. To allow for a 20% dropout rate, 24 participants total will be recruited.