High potency sucralfate in polymerized sucralfate malate paste has a device mechanism of action. It is assumed that the more efficient layering of polymerized sucralfate paste produces adherent restrictive microenvironment across the mucosal lining which advantages the activation of growth factor receptors by growth factor. Restrictive micro-environs generated by cross-linked layers of polymerized sucralfate "crowds" free-moving growth factor, limiting its random movements to "pockets" that overlie growth factor receptors. Spatially limiting the movement of growth factor to the vicinity of its receptor heightens the chances of receptor site activation. This device action leads to expedited healing.