Safety Parameters/Analysis: General health assessments, physical examination and vital signs will be obtained at screening and thereafter at designated clinic visits (or symptom driven as required). Incidence and severity of Adverse and Serious Events including evidence of gluten intolerance and hookworm related complications of Participants will be evaluated formally through structured questionnaires (CSI weekly and QOL at the designated times) to be scrutinised by the designated research nurse and informally through Participant initiated personal contact with a research nurse or clinician. As well, blood for clinical safety and histological results will be scrutinised contemporaneously (by a designated research nurse or designated researcher) for incidence and severity of laboratory abnormalities. Blood results and symptom scores will be coded in a re-identifiable format before adding to an access-restricted and secure database. Screening blood tests to include serum pregnancy test at screening (a positive test will exclude the Participant from entering the trial) and urine pregnancy test if pregnancy is suspected throughout the trial. The 12-month progression to a liberal diet will be monitored by tTG evaluated monthly, with monthly CSI evaluation and Participant contact.