The pharmacological first step is the use of IECAs (ARA II if there is cough), calcium channel blockers, the use of diuretics like the Hydrochlorothiazide 12.5mg (or up to 25mg). If there is orthostatic hypotension, it is considered to start with Amlodipine. In those patients with tachyarrhythmia, heart failure or coronary disease Beta blockers are chosen. Alpha blockers are the last step therapy.