- Neovascular AMD will be defined as the presence of a serous or hemorrhagic neuro-retinal or retinal pigment epithelium detachment, and/or a subretinal neovascular membrane, and/or a subretinal hemorrhage, and/or a peri-retinal fibrous scar. Lesions that are considered to be the result of generalized disease (see exclusion criteria) will be excluded from AMD diagnosis.