The great anti-leukemic efficacy of genetically modified NK cells shown in our preclinical studies, together with the demonstrated feasibility of infusing durable haploidentical NK cells in a non-HSCT setting and the established expertise by the NUH team in cell therapy (the only center in Asia accredited by Foundation for the Accreditation of Cellular Therapy, FACT), form a compelling rationale for the clinical testing of these NK cells.