Measuring the genetic factors in these individuals is an ongoing process that involves routine lab measures using the single existing DNA sample that the volunteers provided during their participation in the Exeter 10000 Project/OBB. As of June 2014, in Exeter 94 genetic variants (aka DNA changes) have been measured in 5600 EXTEND volunteers and 800,000 genetic variants in a subset of 1700 EXTEND volunteers. During the course of the next 4 years, the genetic measures will be extended to all participants (up to 10,000) and all variants (800,000+). These data will be returned to the EXTEND/OBB database as required.