PDS commonly manifests among infants as intractable seizures, generally beginning within hours of birth. Classically multiple types of clinical and electrographic seizures are described among individuals with PDS (24, 28, 29, 30). Prolonged seizures and recurrent episodes of status epilepticus are typical, also reported are recurrent self-limited events including partial seizures, generalized seizures, atonic seizures, myoclonic events, and infantile spasms (27, 30, 31).