ductal carcinoma in situ nuclear pleomorphism, grade 3: markedly pleomorphic nuclei, usually >2.5 red blood cells diameters, with coarse chromatin and multiple nucleoli
ductal carcinoma in situ nuclear pleomorphism, grade 1: monotonous nuclei, 1.5 - 2.0 red blood cells diameters, with finely dispersed chromatin and only occasional nucleoli