user25515: My videos and audio files played fine in Premiere Pro yesterday, but today when I open the project file again, all the audio files, including those in videos, are choppy and laggy during playback. Tried opening new projects and with other audios and vids, the problem still exists. Any ideas ?

user25529: From my experience this can typically occur when Premiere is having either a hard time loading a buffer for the audio, or you're putting too much strain on your computer memory. 
I'd clear out the Premiere cache, which you can do by going to “Preferences > Memory.” 
If it's an issue that occurs through different clips, something tells me it's to do with either the amount of memory Premiere needs to process the realtime feedback for audio, or the bitrate of the clips. If your bitrate is too high, it'll DEFINITELY cause some playback issues.

user37227: Try under Audio Hardware in Preferences, change Input to No Input. Why this had an impact on the audio in the timeline... I have no clue. But it fixed the issue when I had it.

25515: <p>My videos and audio files played fine in Premiere Pro yesterday, but today when I open the project file again, all the audio files, including those in videos, are choppy and laggy during playback. Tried opening new projects and with other audios and vids, the problem still exists. Any ideas ?</p>
 25529: <p>From my experience this can typically occur when Premiere is having either a hard time loading a buffer for the audio, or you're putting too much strain on your computer memory. </p>

<p>I'd clear out the Premiere cache, which you can do by going to “Preferences > Memory.” </p>

<p>If it's an issue that occurs through different clips, something tells me it's to do with either the amount of memory Premiere needs to process the realtime feedback for audio, or the bitrate of the clips. If your bitrate is too high, it'll DEFINITELY cause some playback issues.</p>
 37227: <p>Try under Audio Hardware in Preferences, change Input to No Input. Why this had an impact on the audio in the timeline... I have no clue. But it fixed the issue when I had it.</p>
