user23444: After exporting a time lapse video as H.246 mp4 using Adobe Premiere I realized I wanted a second copy without sound, but I had already changed the settings.  To save time I simply imported the mp4 to Premiere and then exported it again with the same H.246 settings but without the audio channel.
After close analysis of the 2 files I can't perceive any loss in quality, but I worry that I may have lost a tiny bit of quality through this process. Would repeating this process eventually result in noticeable loss of quality?  

user23394: If you give same bitrate setting (I assume it is configurable in Adobe Premiere), I don't expect you perceive the quality difference.
You could use FFMPEG to remove the audio on your first output with -an flag. Command will be like
ffmpeg -i first_output.mp4-c copy -an nosound_output.mp4
Reference

user6066: Compression by default is removing information. “Lossless” compression, if repeated, will indeed result in degradation after a few generations.
Higher compression rates will degrade after fewer generations.

23444: <p>After exporting a time lapse video as H.246 mp4 using Adobe Premiere I realized I wanted a second copy without sound, but I had already changed the settings.  To save time I simply imported the mp4 to Premiere and then exported it again with the same H.246 settings but without the audio channel.</p>

<p>After close analysis of the 2 files I can't perceive any loss in quality, but I worry that I may have lost a tiny bit of quality through this process. Would repeating this process eventually result in noticeable loss of quality?  </p>
 23394: <p>If you give same bitrate setting (I assume it is configurable in Adobe Premiere), I don't expect you perceive the quality difference.</p>

<p>You could use FFMPEG to remove the audio on your first output with <code>-an</code> flag. Command will be like</p>

<p><code>ffmpeg -i first_output.mp4-c copy -an nosound_output.mp4</code></p>

<p><a href="http://www.ffmpeg.org/ffmpeg-doc.html#SEC8" rel="nofollow noreferrer">Reference</a></p>
 6066: <p>Compression by default is removing information. “Lossless” compression, if repeated, will indeed result in degradation after a few generations.</p>

<p>Higher compression rates will degrade after fewer generations.</p>
