user17386: Does a USB3.0 pen/thumb drive have enough speed to handle editing in Premiere Pro Daniel2 codecs ? 

user27196: It depends on the USB flash drive, for example some have > 100 MB/s R/W capability and would be similar to working with a traditional HDD. However USB flash drives have chips which are not meant for constant use and lots of writing, and they don't have wear leveling like a good SSD. This means that the flash drive will go bad sooner and you will lose your data when it does. 
I recommend using a portable SSD to work with your video projects. For example a Samsung T5 series. 

17386: <p>Does a USB3.0 pen/thumb drive have enough speed to handle editing in Premiere Pro Daniel2 codecs ? </p>
 27196: <p>It depends on the USB flash drive, for example some have > 100 MB/s R/W capability and would be similar to working with a traditional HDD. However USB flash drives have chips which are not meant for constant use and lots of writing, and they don't have wear leveling like a good SSD. This means that the flash drive will go bad sooner and you will lose your data when it does. </p>

<p>I recommend using a portable SSD to work with your video projects. For example a Samsung T5 series. </p>
