what did brittany murphy died of?
Pneumonia Cardiac arrest Anemia
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 Murphy died of heart disease in Mackinac Island , Michigan after having been ill for six months . He was staying at the Grand Hotel and was attended by his wife and Drs. L. L. MacArthur and James Keefe . After he suffered from angina pectoris for several years , his death was attributed to aortitis . Two days prior to his death he correctly predicted the findings of his own autopsy : " I think the necropsy will show plaques in my aorta . " 

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 Between 2008 and 2010 , Lebrón was hospitalized multiple times , the first being due to a fall that fractured her hip and an arm , requiring surgery . On September 18 , 2009 , she suffered a notable relapse due to a cardio respiratory affection . Lebrón recovered in a satisfactory manner and issued a press release in appreciation for the public 's support . Complications from this episode of bronchitis , however , persisted throughout 2010 , leading to her death on August 1 , 2010 . Multiple public figures , who support independence or free association for Puerto Rico , immediately lamented Lebrón 's death , praising her activism . Her life was eulogized even in European papers . 

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 On July 5 , 2016 , Manning was taken to a hospital after what media sources characterized as a suicide attempt . The following week , Manning confirmed through an attorney statement that she attempted to end her own life . 

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 In December 2000 , Guillory 's father died of cancer at the age of 53 . 

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 Speculation resumed , however , when Dean Morgan returned to the show for a second time in its fifth season . Cast member James Pickens , Jr. announced that both Heigl and T.R. Knight were set to depart from the show , but he later retracted his comment . During the course of the fifth season , Izzie was diagnosed with metastatic melanoma ( Stage IV ) which spread to her liver , skin and brain . Following the show 's one @-@ hundredth episode wrap party , Heigl revealed she did not know if Izzie would survive , as no one on the production team would disclose her character 's fate to her . It was confirmed in June 2009 that Heigl would return as Izzie for the show 's sixth season . Heigl 's appearances in the season were sporadic , seeing Izzie depart and return twice . Although she was scheduled to appear in the final five episodes of the season , Heigl requested that she be released from her contract 18 months early , and made her final appearance on January 21 , 2010 . Heigl explained that she wanted to spend more time with her family , and did not think it would be respectful to Grey 's Anatomy viewers to have Izzie return and depart yet again . 
