[{"from": "human", "value": "Given SMILES, write its water solubility expressed as a logarithm in mol/L in 25 \u00b0C. ->  COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1\n"}, {"from": "gpt", "value": " -4.805\n"}]