[{"from": "human", "value": "Create a molecule that satisfies the conditions outlined in the description. The molecule is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension. It was first approved by the FDA in 2013. Macitentan differs from its predecessor [bosentan] due to its lower risk of hepatotoxicity."}, {"from": "gpt", "value": "[C][C][C][N][S][=Branch1][C][=O][=Branch1][C][=O][N][C][=C][Branch2][Ring1][Branch2][C][=Branch1][=Branch1][=N][C][=N][Ring1][=Branch1][O][C][C][O][C][=N][C][=C][Branch1][Branch1][C][=N][Ring1][=Branch1][Br][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][Br]"}]