[{"from": "human", "value": "Create a molecule with the structure as the one described. The molecule is an endogenous metabolite of cholesterol produced by the hydroxylation of the carbon at position 27 by the enzyme sterol 26-hydroxylase, mitochondrial (CYP27A1). Some neoplasms produce excess of 27-hydroxycholesterol (27HC) or inhibit its catabolism, and high cholesterol levels are correlated with elevated levels of 27HC; under these conditions, 27HC may have deleterious selective estrogen receptor modulator (SERM) and liver X receptor (LXR) agonistic activities. As a SERM, 27HC binds to and prevents the activation of estrogen receptors (ERs) in the vasculature. This prevents ER-mediated vasodilation and abrogates the cardiovascular protective effects of estrogen. However, 27HC binds to and activates ERs and LXRs in breast tissue, which stimulates ER-dependent breast cancer cell growth and metastasis."}, {"from": "gpt", "value": "[C][C@H1][Branch2][Ring2][O][C][C][C][C@@H1][Branch1][C][C][C@H1][C][C][C@@H1][C@@][Ring1][Branch1][Branch2][Ring1][=Branch2][C][C][C@H1][C@H1][Ring1][=Branch1][C][C][=C][C@@][Ring1][=Branch1][Branch1][#Branch2][C][C][C@@H1][Branch1][Ring2][C][Ring1][=Branch1][O][C][C][C][O]"}]