[{"from": "human", "value": "Use the given information to create a molecule that fulfills the desired purpose. The molecule is an orally bioavailable inhibitor of cyclin-dependent kinases 8 and 19 (CDK8/19), with potential antineoplastic and chemoprotective activities. Upon oral administration, CDK8/19 inhibitor SEL 120 targets, binds to and inhibits the activity of CDK8/19, which prevents activation of CDK8/19-mediated oncogenic signaling pathways, blocks selective transcription of various tumor-promoting genes, and inhibits proliferation of CDK8/19-overexpressing tumor cells. CDK8/19, serine/threonine kinases involved in the regulation of the cell cycle, are overexpressed in certain cancer cell types and play key roles in tumor cell proliferation."}, {"from": "gpt", "value": "[C][C][=C][C][=C][Branch2][Ring1][Branch1][C][C][C][N][Ring1][=Branch1][C][=Branch1][Ring2][=N][Ring1][=Branch2][N][C][C][N][C][C][Ring1][=Branch1][C][=Branch1][=Branch1][=C][Ring2][Ring1][C][Br][Br].[Cl]"}]