[{"from": "human", "value": "Synthesize a molecule that matches the given characteristics. The molecule is a second-generation epothilone with potential antineoplastic activity. Epothilone KOS-1584 binds to tubulin and induces microtubule polymerization and stabilizes microtubules against depolymerization, which may result in the inhibition of cell division, the induction of G2/M arrest, and apoptosis. Compared to first-generation epothilones, this agent exhibits greater safety and efficacy with an enhanced pharmaceutical profile, including enhanced water solubility and tumor penetration, and reduced CNS exposure. In addition, epothilone KOS-1584 is a poor substrate for the P-glycoprotein (P-gp) drug efflux pump."}, {"from": "gpt", "value": "[C][C@H1][/C][=C][/C][/C][=Branch2][Branch1][Branch1][=C][\\C][C@H1][Branch2][Ring1][S][O][C][=Branch1][C][=O][C][C@@H1][Branch2][Ring1][Branch1][C][Branch1][=C][C][=Branch1][C][=O][C@@H1][Branch1][=Branch1][C@H1][Ring2][Ring1][C][O][C][Branch1][C][C][C][O][/C][=Branch1][N][=C][/C][=C][S][C][=Branch1][Ring2][=N][Ring1][Branch1][C][/C][/C]"}]