[{"from": "human", "value": "Design a molecule that meets the criteria outlined in the description. The molecule is under investigation in clinical trial NCT02319369 (Safety, Tolerability and Pharmacokinetics of Milademetan Alone and With 5-Azacitidine (AZA) in Acute Myelogenous Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS))."}, {"from": "gpt", "value": "[C][C][Branch2][=Branch1][=N][C][C][C][Branch1][Branch1][C][C][Ring1][=Branch1][C@@][Branch2][Ring2][=N][C@H1][Branch2][Ring1][O][C@@H1][Branch1][Ring2][N][Ring1][#Branch1][C][=Branch1][C][=O][N][C@@H1][C][C][C@H1][Branch1][Branch1][O][C][Ring1][=Branch1][C][=Branch1][C][=O][N][C][=C][Branch1][#Branch2][C][=Branch1][=Branch1][=N][C][=C][Ring1][=Branch1][Cl][F][C][=C][Branch1][#Branch2][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][Cl][N][C][Ring2][Ring1][P][=O][C]"}]