[{"from": "human", "value": "Generate a molecule based on this description. The molecule is an orally bioavailable androgen receptor (AR) antagonist with potential antineoplastic activity. Upon oral administration, proxalutamide binds to AR in target tissues, inhibits androgen-induced receptor activation, and facilitates the formation of inactive complexes that cannot translocate to the nucleus. This prevents binding to and transcription of AR-responsive genes that regulate prostate cancer cell proliferation. In addition, proxalutamide induces AR downregulation, thereby further preventing AR-mediated signaling. This ultimately leads to an inhibition of growth in AR-expressing prostate cancer cells. AR is overexpressed in prostate cancer and plays a key role in prostate cancer cell proliferation."}, {"from": "gpt", "value": "[C][C][Branch2][Branch1][=C][C][=Branch1][C][=O][N][Branch2][Ring1][N][C][=Branch1][C][=S][N][Ring1][#Branch1][C][=C][N][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][C][C][C][C][=N][C][=C][O][Ring1][Branch1][C][=C][Branch2][Ring1][Branch1][C][=Branch1][#Branch2][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][C][#N][C][Branch1][C][F][Branch1][C][F][F][F][C]"}]