[{"from": "human", "value": "Create a molecule that satisfies the conditions outlined in the description. The molecule is a drug treatment of hormone receptor-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor."}, {"from": "gpt", "value": "[C][C@][C][C][C@H1][C][Branch1][#Branch2][C@@H1][Ring1][=Branch1][C][C][C@@H1][Ring1][=Branch2][O][C@@H1][Branch1][#C][C][C][=C][Ring1][O][C][=C][C][=Branch1][Ring2][=C][Ring1][=Branch1][O][C][C][C][C][C][C][C][C][C][S][=Branch1][C][=O][C][C][C][C][Branch1][=Branch2][C][Branch1][C][F][Branch1][C][F][F][Branch1][C][F][F]"}]