[{"from": "human", "value": "Provide a brief overview of this molecule. [C][O][C][=C][C][=Branch1][O][=C][C][=Branch1][Branch1][=C][Ring1][=Branch1][O][O][C][C@H1][C@@H1][C@H1][Branch1][#Branch1][C][O][C][Ring1][Branch1][=O][C@@H1][Branch2][Ring1][C][C][=C][C][=C][Branch1][#Branch1][C][=C][Ring1][=C][Ring1][=Branch1][O][C][O][Ring1][#Branch1][O][C@H1][C@@H1][Branch2][Ring1][N][C@H1][Branch2][Ring1][#Branch1][C@H1][C@H1][Branch1][Ring2][O][Ring1][=Branch1][C][O][C@H1][Branch1][Ring2][O][Ring1][#Branch1][C][=C][C][=C][S][Ring1][Branch1][O][O]"}, {"from": "gpt", "value": "The molecule is a semisynthetic derivative of podophyllotoxin with antineoplastic activity. Teniposide forms a ternary complex with the enzyme topoisomerase II and DNA, resulting in dose-dependent single- and double-stranded breaks in DNA, DNA: protein cross-links, inhibition of DNA strand religation, and cytotoxicity. This agent acts in the late S or early G phase of the cell cycle. (NCI04)"}]