[{"from": "human", "value": "Could you give me a brief overview of this molecule? [C][C][=C][Branch2][Ring2][Branch2][C][=Branch1][C][=O][C][=C][Branch1][Branch1][C][Ring1][#Branch1][=O][N][C][C@H1][C@@H1][Branch2][Ring1][C][C@@][Ring1][Branch1][Branch1][O][C@@H1][Ring1][#Branch2][C][O][C][=Branch1][C][=O][N][O][C][N][Ring1][N][N][C][C][S][S][C][C][N][C][=Branch1][C][=O][C][C][C@@H1][Branch1][=Branch1][C][=Branch1][C][=O][O][N]"}, {"from": "gpt", "value": "The molecule is a semisynthetic water-soluble disulfide derivative of the antineoplastic antibiotic mitomycin C.  Activated by serum and glutathione, KW-2149 causes interstrand DNA cross-links and DNA-protein cross-links, resulting in single-strand DNA breaks and inhibition of DNA synthesis. (NCI04)"}]