[{"from": "human", "value": "What can you tell me about this molecule? [C][O][C][=C][C][=Branch1][N][=C][C][=Branch1][=Branch1][=C][Ring1][=Branch1][O][C][O][C][C][C][=C][N][=C][Branch1][=Branch1][N][=C][Ring1][=Branch1][N][N]"}, {"from": "gpt", "value": "The molecule is a synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties.  As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid.  The antibacterial activity of this agent is potentiated by sulfonamides. (NCI04)"}]