[{"from": "human", "value": "Describe this molecule. [B][Branch2][=Branch1][=Branch1][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][C@H1][C][C][C@][Branch2][Branch1][Ring2][C@H1][Branch2][Ring2][=Branch2][C@@H1][Ring1][=Branch1][C@@H1][Branch1][Ring2][C][Ring1][N][C][C][C][C][C][C][C][C][C][S][=Branch1][C][=O][C][C][C][C][Branch1][=Branch2][C][Branch1][C][F][Branch1][C][F][F][Branch1][C][F][F][C][C][C@@H1][Ring2][Ring1][=N][O][C][Branch1][C][O][O]"}, {"from": "gpt", "value": "The molecule is an orally bioavailable selective estrogen receptor degrader/downregulator (SERD) and a structural analog of fulvestrant, with potential antineoplastic activity. Upon oral administration, SERD ZB-716 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells."}]