[{"from": "human", "value": "Describe this molecule. [C][C][=C][S][C][=Branch1][Ring2][=C][Ring1][Branch1][C][=N][N][=C][Branch1][O][C][=C][C][=C][C][=C][Ring1][=Branch1][Ring1][#Branch2][N][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][O][C][=C][Branch1][#Branch1][C][=C][C][=N][Ring1][=Branch1][C][=N][C][=Branch1][=Branch1][=N][C][=C][Ring1][=Branch1][N]"}, {"from": "gpt", "value": "The molecule is a small-molecule inhibitor of Aurora kinases A, B and C with potential antineoplastic activity. Aurora kinase inhibitor AMG 900 selectively binds to and inhibits the activities of Aurora kinases A, B and C, which may result in inhibition of cellular division and proliferation in tumor cells that overexpress these kinases. Aurora kinases are serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis and are overexpressed by a wide variety of cancer cell types."}]