[{"from": "human", "value": "Please give me some details about this molecule. [C][N][C][=C][Branch1][Branch1][C][=N][Ring1][Branch1][C][=C][N][C][=Branch2][Ring2][Branch2][=N][C][=C][Ring1][Branch1][S][=Branch1][C][=O][=Branch1][C][=O][N][C][=C][Branch1][Branch1][C][=N][Ring1][Branch1][N][=C][C][=Branch1][Ring2][=C][Ring1][Branch2][C][=C][N][Branch1][Branch1][N][=C][Ring1][Branch1][C][C][=C][Ring2][Ring1][O]"}, {"from": "gpt", "value": "The molecule is an orally bioavailable, small molecule inhibitor of the oncoprotein c-Met (hepatocyte growth factor receptor; HGFR), with potential antineoplastic activity. Upon oral administration, glumetinib targets and binds to the c-Met protein, thereby disrupting c-Met-dependent signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing constitutively activated c-Met protein. c-Met protein is overexpressed or mutated in many tumor cell types and plays key roles in tumor cell proliferation, survival, invasion, metastasis, and tumor angiogenesis."}]