[{"from": "human", "value": "Please give me some details about this molecule. [C][C@@H1][Branch1][=C][C][=C][N][C][=C][N][=C][Ring1][Branch1][C][=C][Ring1][=Branch2][N][C][=N][C][=Branch1][#Branch2][=C][N][=C][Ring1][=Branch1][N][=N][Ring1][=Branch2][C][=C][N][Branch1][Branch1][N][=C][Ring1][Branch1][C]"}, {"from": "gpt", "value": "The molecule is an orally bioavailable inhibitor of the c-Met receptor tyrosine kinase with potential antineoplastic activity. Savolitinib selectively binds to and inhibits the activation of c-Met in an ATP-competitive manner, and disrupts c-Met signal transduction pathways. This may result in cell growth inhibition in tumors that overexpress the c-Met protein. C-Met encodes the hepatocyte growth factor receptor tyrosine kinase and plays an important role in tumor cell proliferation, survival, invasion, and metastasis, and tumor angiogenesis; this protein is overexpressed or mutated in a variety of cancers."}]