[{"from": "human", "value": "Provide a description of this molecule. [C][C][C@H1][Branch1][C][C][C][=Branch1][C][=O][O][C@H1][C][C@@H1][Branch2][Ring2][C][C][=C][C@H1][Ring1][=Branch1][C@H1][Branch1][=Branch2][C@H1][Branch1][Branch1][C][=C][Ring1][=Branch1][C][C][C][C@H1][Branch1][N][C][C@H1][Branch1][#Branch1][C][C][=Branch1][C][=O][O][O][O][O]"}, {"from": "gpt", "value": "The molecule is a synthetic lipid-lowering agent. Pravastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. Pravastatin lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing MHC II (major histocompatibility complex II) on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. (NCI04)"}]