[{"from": "human", "value": "Provide a brief overview of this molecule. [C][C][=C][C@H1][Branch2][=Branch2][C][C][=Branch1][C][=O][C@@][Branch2][Branch2][=Branch2][C@H1][Branch2][Branch2][Ring2][C][C@@H1][C@][Branch2][=Branch1][P][C@H1][Ring1][=Branch1][C@@H1][Branch2][Branch1][=N][C@@][Branch1][Branch2][C][Ring1][=N][Branch1][C][C][C][C@H1][Branch2][Ring2][=Branch1][C@@H1][Ring2][Ring1][C][O][C][=Branch1][C][=O][C@@H1][Branch2][Ring1][Branch2][C@H1][Branch1][#Branch1][C][C][Branch1][C][C][C][N][C][=Branch1][C][=O][O][C][Branch1][C][C][Branch1][C][C][C][O][O][C][=Branch1][C][=O][O][Ring2][Ring1][N][O][C][=Branch1][C][=O][C][=C][C][=C][C][=C][Ring1][=Branch1][Branch1][=Branch1][C][O][Ring2][Ring2][O][O][C][=Branch1][C][=O][C][O][C][O][C][=Branch1][C][=O][C]"}, {"from": "gpt", "value": "The molecule is a semisynthetic, second-generation taxane derivative with potential antineoplastic activity. Ortataxel binds to and stabilizes tubulin molecules, thereby interfering with the dynamics of microtubule assembly/disassembly. This results in the inhibition of cell division and cellular proliferation. As it represents a poor substrate for P-glycoprotein (P-gp), multi-drug resistance protein (MRP-1) and breast cancer resistance protein (BCRP) mediated efflux, ortataxel modulates multi-drug resistance mechanisms and may be useful for treating multi-drug resistant tumors that express Pgp, MRP-1 and BCRP."}]