[{"from": "human", "value": "Could you give me a brief overview of this molecule? [C][#C][C@][Branch2][Ring1][O][C@H1][Branch2][Ring1][Branch1][O][C@H1][Branch1][Branch1][C@@H1][Ring1][Branch1][O][N][C][=C][C][=Branch1][=Branch1][=N][C][Ring1][=Branch1][=O][N][C][O][O]"}, {"from": "gpt", "value": "The molecule is a synthetic cytidine nucleoside containing a covalently bound ethynyl group with potential antineoplastic and radiosensitizing activities. 3'-C-ethynylcytidine is metabolized in tumor cells to ethynylcytidine triphosphate (ECTP), which inhibits RNA synthesis by competitive inhibition of RNA polymerases I, II and III; subsequently, RNase L is activated, resulting in apoptosis. RNase L is a potent antiviral and antiproliferative endoribonuclease that cleaves singled stranded RNA, causes 28s rRNA fragmentation, and activates Janus Kinase (JAK), a mitochondrial-dependent apoptosis signaling molecule."}]