[{"from": "human", "value": "What can you tell me about this molecule? [C][C@][Branch2][Ring2][Branch1][C][C][C][N][Ring1][Branch1][C][=N][N][C][=C][C][=C][Ring1][Branch1][C][=Branch1][Ring2][=N][Ring1][=Branch2][N][C][=N][N][C][=Branch1][Ring2][=C][Ring1][Branch1][C][C][C][Ring1][Ring1][C][=Branch1][C][=O][N][C][=C][N][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][F]"}, {"from": "gpt", "value": "The molecule is an oral small molecule inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (InsR) tyrosine kinases with potential antineoplastic activity. Dual IGF-IR/InsR inhibitor BMS-754807 binds reversibly to and inhibits the activities of IGF-1R and InsR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-1R and InsR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in mitogenesis, angiogenesis, and tumor cell survival."}]