[{"from": "human", "value": "Could you provide a description of this molecule? [C][C@@H1][C@H1][Branch2][#Branch2][=C][C@@H1][Branch2][#Branch2][=Branch2][C][C@@H1][Branch1][Ring2][O][Ring1][=Branch1][O][C@@H1][C][C@@H1][Branch1][#Branch2][O][C@@H1][Branch1][Branch1][C@H1][Ring1][=Branch1][O][C][O][C][=C][C][=C][C][=C][Branch2][#Branch1][Branch2][C][=Branch1][C][=O][C@H1][Branch2][Ring1][=Branch2][C@@H1][Branch1][Ring2][C][Ring1][#Branch1][C@@H1][Branch1][=C][C][=Branch1][C][=O][C@H1][Branch1][=Branch1][C@@H1][Branch1][C][C][O][O][O][C][O][C@H1][C][C@H1][Branch1][N][C@@H1][Branch1][Branch2][C@H1][Branch1][Ring2][O][Ring1][=Branch1][C][O][O][C@H1][C][C@H1][Branch1][N][C@H1][Branch1][Branch2][C@H1][Branch1][Ring2][O][Ring1][=Branch1][C][O][O][C@H1][C][C@][Branch1][N][C@@H1][Branch1][Branch2][C@H1][Branch1][Ring2][O][Ring1][=Branch1][C][O][Branch1][C][C][O][C][=Branch1][=C][=C][Ring2][Branch1][C][C][=Branch1][=Branch1][=C][Ring2][Branch1][=Branch1][C][O][O][O][O]"}, {"from": "gpt", "value": "The molecule is an antibiotic isolated from the bacterium Streptomyces plicatus with antineoplastic activity. Plicamycin, also known as mithramycin, binds to the minor groove of DNA at GC-rich sites, resulting in inhibition of RNA synthesis; this agent also inhibits mRNA expression, resulting in a reduction in protein synthesis. In addition, plicamycin may inhibit bone resorption by down regulating transcription of c-src, an oncogene involved in bone metabolism and resorption. (NCI04)"}]