[{"from": "human", "value": "What can you tell me about this molecule? [C][C][C@H1][Branch1][C][C][C][=Branch1][C][=O][O][C@H1][C][C@@H1][Branch2][Ring2][C][C][=C][C@H1][Ring1][=Branch1][C@H1][Branch1][=Branch2][C@H1][Branch1][Branch1][C][=C][Ring1][=Branch1][C][C][C][C@H1][Branch1][N][C][C@H1][Branch1][#Branch1][C][C][=Branch1][C][=O][O][O][O][O]"}, {"from": "gpt", "value": "The molecule is the 6-alpha-hydroxy acid form of [mevastatin]. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. This drug was developed by Sankyo Co. Ltd.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved in 1991.  Pravastatin is made through a fermentation process in which [mevastatin] is first obtained. The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation with Streptomyces carbophilus to introduce the allylic 6-alcohol group."}]