[{"from": "human", "value": "Provide a brief overview of this molecule. [C][=C][C][=Branch2][Ring1][O][=C][C][=C][Ring1][=Branch1][C][=C][O][C][=C][C][=Branch1][=N][=C][C][=Branch1][Branch2][=C][Ring1][=Branch1][C][Ring1][#Branch2][=O][O][O][O]"}, {"from": "gpt", "value": "The molecule is a soy-derived isoflavone and phytoestrogen with antineoplastic activity. Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation.  This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest.  Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities. (NCI04)"}]