[{"from": "human", "value": "Describe this molecule. [C][C@][C][C][C@H1][C@H1][Branch1][#Branch2][C@@H1][Ring1][=Branch1][C][C][C][Ring1][=Branch2][=O][C][C][C][=C][Ring1][O][C][=C][C][=Branch1][Branch1][=C][Ring1][=Branch1][O][O]"}, {"from": "gpt", "value": "The molecule is a metabolite formed during the catabolism of estrone by the liver through the hydroxylation of the carbon at position 4 by cytochrome P450 (CYP) family enzymes, with potential carcinogenic activity. The mechanism of action for the tumor promoting activity of 4-hydroxyestrone is not known but this metabolic product has increased estrogenic activity compared to the parent compound. Additionally, oxidation of 4-hydroxyestrone generates compounds with free radicals that are capable of removing purines from DNA, which can cause mutagenesis and can lead to tumorigenesis."}]