[{"from": "human", "value": "Provide a brief overview of this molecule. [C][N][C][=C][C][=Branch2][Ring1][#Branch2][=C][Branch1][#C][C][=C][Ring1][=Branch1][S][=Branch1][C][=O][=Branch1][C][=O][N][Ring1][N][S][=Branch1][C][=O][=Branch1][C][=O][N][Cl]"}, {"from": "gpt", "value": "The molecule is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension. Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors or angiotensin II receptor blockers.  Hydrochlorothiazide was granted FDA approval on 12 February 1959."}]