[{"from": "human", "value": "Provide a description of this molecule. [C][C][N][Ring1][Ring1][P][=Branch1][C][=S][Branch1][=Branch1][N][C][C][Ring1][Ring1][N][C][C][Ring1][Ring1]"}, {"from": "gpt", "value": "The molecule is a polyfunctional, organophosphorus alkylating agent and a stable derivative of N,N',N''-triethylenephosphoramide (TEPA), with antineoplastic activity. Upon administration, thiotepa is converted into highly reactive ethylenimine groups, which covalently bind to nucleophilic groups in DNA and demonstrate a preference for the N7 position of guanine bases. This induces crosslinking of alkylated guanine bases in double-stranded DNA, interferes with both DNA replication and cell division, and results in both the induction of apoptosis and the inhibition of cell growth."}]