[{"from": "human", "value": "What can you tell me about this molecule? [C][C@@H1][C][C][=C][Branch2][Ring2][=N][C@H1][Branch1][=C][N][Ring1][=Branch1][C][C][Branch1][Ring1][C][O][Branch1][C][F][F][C][=C][Branch2][Ring1][#Branch1][C][=C][Branch1][=Branch1][C][=C][Ring1][=Branch1][F][N][C][C][N][Branch1][Ring2][C][Ring1][Ring2][C][C][C][F][F][N][C][=C][C][=C][C][=C][Ring2][Ring2][C][Ring1][=Branch1]"}, {"from": "gpt", "value": "The molecule is an orally available selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, giredestrant specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells."}]