[{"from": "human", "value": "Could you provide a description of this molecule? [C][N][C][C][C][Branch1][Branch1][C][C][Ring1][=Branch1][C][N][C][=N][N][C][=Branch2][Ring1][=Branch2][=N][C][=C][Ring1][Branch1][C][=C][C][=Branch1][=Branch1][=C][C][=C][Ring1][=Branch1][O][C][Branch1][C][F][Branch1][C][F][F][C][=C][Ring2][Ring1][Ring2]"}, {"from": "gpt", "value": "The molecule is a small-molecule pan-PIM protein kinase inhibitor with potential antineoplastic activity. PIM kinase inhibitor SGI-1776 binds to and inhibits the activities of PIM-1, -2 and -3 serine/threonine kinases, which may result in the interruption of the G1/S phase cell cycle transition, the expression of pro-apoptotic Bcl2 proteins and tumor cell apoptosis. PIM kinases play key roles in cell cycle progression and apoptosis inhibition and may be overexpressed in various malignancies."}]