[{"from": "human", "value": "Could you give me a brief overview of this molecule? [C][C][=C][C][=Branch2][Ring1][#Branch2][=N][C][=N][N][Ring1][=Branch1][C][=C][Ring1][=Branch2][N][C][=Branch1][C][=O][O][C][C@@H1][C][O][C][C][N][Ring1][=Branch1][N][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][N][Branch1][Branch1][N][=C][Ring1][#Branch1][C][C][=C][C][=Branch1][=Branch1][=C][C][=C][Ring1][=Branch1][F]"}, {"from": "gpt", "value": "The molecule is an orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. (NCI05)"}]