[{"from": "human", "value": "Provide a brief overview of this molecule. [Br-1]"}, {"from": "gpt", "value": "The molecule is most abundant as a bromide ion. Physiologically, it exists as an ion in the body. A bromide is a chemical compound containing a bromide ion or ligand. Bromide compounds, especially potassium bromide, were frequently used as sedatives in the 19th and early 20th century. Their use in over-the-counter sedatives and headache remedies (such as Bromo-Seltzer) in the United States extended to 1975, when bromides were withdrawn as ingredients, due to chronic toxicity. Bromide is present in typical seawater (35 PSU) with a concentration of around 65 mg/L, which is around 0.2% of all dissolved salts. Bromide is needed by eosinophils (white blood cells of the granulocyte class, specialized for dealing with multi-cellular parasites), which use it to generate antiparasitic brominating compounds such as hypobromite, by the action of eosinophil peroxidase, a haloperoxidase enzyme which is able to use chloride, but preferentially uses bromide when available."}]