[{"from": "human", "value": "Please give me some details about this molecule. [C][C][=C][Branch2][Ring2][#C][C][=Branch1][C][=O][N][Branch2][Ring1][S][C][=N][C][=Branch1][Branch2][=N][C][=C][Ring1][O][Ring1][=Branch1][N][C][=N][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][C][C][C][N][C][C][Ring1][=Branch1][C][C][C][C][C][Ring1][Branch1][C][=Branch1][C][=O][C]"}, {"from": "gpt", "value": "The molecule is a cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. Upon administration, dalpiciclib selectively inhibits cyclin-dependent kinase 4 (CDK4) and 6 (CDK6). This inhibits retinoblastoma (Rb) protein phosphorylation early in the G1 phase, which prevents CDK-mediated G1-S phase transition and leads to cell cycle arrest. This suppresses DNA replication and decreases tumor cell proliferation. CDK4 and 6 are serine/threonine kinases that are upregulated in many tumor cell types and play a key role in the regulation of cell cycle progression."}]