[{"from": "human", "value": "Could you give me a brief overview of this molecule? [C][C][=C][C][=Branch2][Ring1][P][=N][C][=Branch2][Ring1][O][=N][C][Ring1][=Branch1][=N][C][=C][Ring1][#Branch2][C][C][=C][Branch1][O][C][=C][C][=Branch1][Ring2][=C][Ring1][=Branch1][O][C][O][C][N][N]"}, {"from": "gpt", "value": "The molecule is a synthetic antifolate agent with antiparasitic, antipsoriatic and antitumor properties. Piritrexim inhibits the enzyme dihydrofolate reductase enzyme, thereby disrupting folate metabolism and DNA synthesis and cell division. (NCI04)"}]