[{"from": "human", "value": "Describe this molecule. [C][C@@H1][C][O][C][=Branch1][Ring2][=N][Ring1][Branch1][N][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][N][=C][N][=C][Ring1][Branch2][N][C][=C][C][=Branch1][P][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][O][C][C][=N][C][=C][S][Ring1][Branch1][Cl]"}, {"from": "gpt", "value": "The molecule is an oral, selective, reversible, small molecule tyrosine kinase inhibitor of both ErbB-2 (Her-2/neu) and EGFR. Over-expression of ErbB-2 and EGFR receptors in tumors is predictive of poor prognosis in cancer patients. Varlitinib has shown significant anti-tumor activity in preclinical models of human breast, lung, and epidermal carcinoma tumors."}]