[{"from": "human", "value": "What can you tell me about this molecule? [C][C][C][C][C][C][C][C][/C][=C][\\C][C][C][C][C][C][C][C][=Branch1][C][=O][O][C][C@H1][Branch2][Branch2][=Branch1][C][O][P][=Branch1][C][=O][Branch1][C][O][O][C][C][N][C][=Branch1][C][=O][C][C][C][C][C][=Branch1][C][=O][N][C][C][C][O][C@H1][C@@H1][Branch2][Branch1][=N][C@H1][Branch2][Branch1][Branch2][C@@H1][Branch1][=Branch2][C@H1][Branch1][Ring2][O][Ring1][=Branch1][C][O][O][C@H1][C@@H1][Branch2][Ring2][=Branch1][C@H1][Branch1][=N][C@H1][Branch1][=Branch2][C@H1][Branch1][Ring2][O][Ring1][=Branch1][C][O][O][O][C@@H1][C@@H1][Branch1][P][C@H1][Branch1][=N][C@H1][Branch1][=Branch2][C@H1][Branch1][Ring2][O][Ring1][=Branch1][C][O][O][O][O][O][O][N][C][=Branch1][C][=O][C][O][C][=Branch1][C][=O][C][C][C][C][C][C][C][/C][=C][\\C][C][C][C][C][C][C][C]"}, {"from": "gpt", "value": "The molecule is a synthetic alpha Gal (aGal) molecule, with potential immunomodulating and antineoplastic activities. Upon intratumoral injection of aGal AGI-134, aGal coats the cancer cell membranes and triggers an anti-aGal antibody-mediated immune response leading to an initial complement-dependent and antibody-dependent cellular cytotoxicity (ADCC). This cytotoxicity causes release from tumor cells and subsequent uptake of released tumor-associated antigens (TAAs) by antigen-presenting cells (APCs). This may activate a systemic immune response against the TAAs and may eradicate cancer cells. aGal is a cell-surface carbohydrate antigen not expressed by humans while being expressed by all other mammals and bacteria. Anti-aGal antibodies are continuously and abundantly produced by humans due to exposure to aGal present on intestinal bacteria in the digestive system."}]