[{"from": "human", "value": "Could you give me a brief overview of this molecule? [C][=C][C][=Branch1][S][=C][C][=C][Ring1][=Branch1][C][C@@H1][Branch1][=Branch1][C][=Branch1][C][=O][O][N][N+1][Branch1][Ring2][C][C][Cl][Branch1][Ring2][C][C][Cl][O-1].[Cl].[Cl]"}, {"from": "gpt", "value": "The molecule is a small molecule inhibitor of hypoxia inducible factor (HIF)-1 alpha currently in a clinical trial in patients with advanced metastatic cancer and lymphoma. PX-478 was effective in models of both non-small cell lung cancer and small cell lung cancer that express HIF-1 alpha."}]