[{"from": "human", "value": "Provide a description of this molecule. [C][C@][C][C@@H1][Branch2][Branch1][C][C@H1][C@H1][Branch2][Ring1][N][C@@H1][Ring1][=Branch1][C][C@@H1][C@][Ring1][=Branch2][Branch1][N][O][C][Branch1][Ring2][O][Ring1][Branch1][Branch1][C][C][C][C][=Branch1][C][=O][C][O][C][C][C][=C][C][=Branch1][C][=O][C][=C][C@][Ring2][Ring1][Branch2][Ring1][#Branch1][C][O]"}, {"from": "gpt", "value": "The molecule is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated as a homodimer into the nucleus, where transcription activation via glucocorticoid response elements within glucocorticoid-responsive genes occur. This agent induces transcription of genes coding for anti-inflammatory proteins, including lipocortin-1, interleukin-10, interleukin-1 receptor antagonist and neutral endopeptidase. Increased synthesis of lipocortin-1 has an inhibitory effect on phospholipase A2, which in turn inhibits the release arachidonic acid, thereby controlling the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes."}]