[{"from": "human", "value": "Provide a description of this molecule. [C][C][N][Branch1][#C][P][=Branch1][C][=O][Branch1][Branch1][O][C][Ring1][#Branch1][N][C][C][Cl][C][C][Cl]"}, {"from": "gpt", "value": "The molecule is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppresive agent. The exact mechanism of ifosfamide has not been determined, but appears to be similar to other alkylating agents. Ifosfamide requires biotransformation in the liver by mixed-function oxidases (cytochrome P450 system) before it becomes active. After metabolic activation, active metabolites of ifosfamide alkylate or bind with many intracellular molecular structures, including nucleic acids. The cytotoxic action is primarily through the alkylation of DNA, done by attaching the N-7 position of guanine to its reactive electrophilic groups. The formation of inter and intra strand cross-links in the DNA results in cell death."}]