[{"from": "human", "value": "Please give me some details about this molecule. [C][C@@H1][C@@H1][C][C@][Branch2][=C][=Branch1][C@@H1][Branch2][=N][S][/C][=C][/C][=C][Branch2][=N][Branch2][/C][C][=C][C][=Branch1][=N][=C][Branch1][=Branch2][C][=Branch1][Ring2][=C][Ring1][=Branch1][O][C][Cl][N][Branch2][O][P][C][=Branch1][C][=O][C][C@@H1][Branch1][N][C@][Branch1][Branch2][C@H1][Ring2][Ring1][#Branch2][O][Ring1][Ring1][C][O][C][=Branch1][C][=O][C@H1][Branch1][C][C][N][Branch1][C][C][C][=Branch1][C][=O][C][C][S][S][C][C@@H1][Branch1][=Branch1][C][=Branch1][C][=O][N][N][C][=Branch1][C][=O][C@@H1][C][S][S][C][C@@H1][Branch2][=Branch1][S][C][=Branch1][C][=O][N][C@H1][Branch2][Branch1][O][C][=Branch1][C][=O][N][C@@H1][Branch2][Ring2][Ring2][C][=Branch1][C][=O][N][C@H1][Branch2][Ring1][=Branch1][C][=Branch1][C][=O][N][C@H1][Branch1][=Branch2][C][=Branch1][C][=O][N][Ring2][Ring1][=Branch2][C@@H1][Branch1][C][C][O][C][C][C][C][N][C][C][=C][N][C][=C][C][=C][C][=C][Ring1][=Branch1][Ring1][=Branch2][C][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][O][N][C][=Branch1][C][=O][C@@H1][Branch1][#Branch2][C][C][=C][C][=C][C][=C][Ring1][=Branch1][N][C][\\C][O][C][Branch1][#Branch2][N][C][=Branch1][C][=O][O][Ring2][=Branch2][#Branch1][O]"}, {"from": "gpt", "value": "The molecule is a miniaturized drug conjugate composed of a peptide analog of somatostatin that targets the somatostatin receptor 2 (SSTR2) and is conjugated, through a cleavable linker, to the microtubule-binding cytotoxic maytansinoid DM1 (mertansine), with potential anti-tumor activity. Upon administration, the peptide ligand moiety of nendratareotide uzatansine targets and binds to SSTR2, which is overexpressed on certain tumor cell types. Binding stimulates SSTR2-mediated endocytosis of the agent; upon internalization, the DM1 moiety is released and binds to tubulin, thereby disrupting microtubule assembly/disassembly dynamics. This inhibits both cell division and the proliferation of SSTR2-expressing cancer cells. Compared to antibody-drug conjugates (ADCs), miniaturized drug conjugates are much smaller and can more easily penetrate and distribute in dense tumor tissue."}]