[{"from": "human", "value": "Could you give me a brief overview of this molecule? [C][=N][C][=C][Branch2][Ring1][#C][N][=C][Branch2][Ring1][=Branch2][N][=C][Ring1][=Branch1][N][Ring1][=Branch2][C@H1][C@H1][Branch1][=N][C@@H1][Branch1][=Branch2][C@H1][Branch1][Ring2][O][Ring1][Branch1][C][O][O][O][F][N]"}, {"from": "gpt", "value": "The molecule is a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Administered parenterally as a phosphate salt, fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase alpha, ribonucleotide reductase and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth.  (NCI04)"}]