[{"from": "human", "value": "Describe this molecule. [C][C][C@@][Branch2][Branch1][Ring1][C][=C][Branch1][#Branch1][C][O][C][Ring1][=Branch1][=O][C][=Branch1][C][=O][N][C][C][=C][Branch2][Ring1][Ring2][C][=C][C][=C][C][=C][Ring1][=Branch1][N][=C][Ring1][#Branch2][C][Ring1][=N][=C][Ring2][Ring1][=Branch1][C][C][Si][Branch1][C][C][Branch1][C][C][C][O]"}, {"from": "gpt", "value": "The molecule is a synthetic silicon-containing agent related to camptothecin with antineoplastic properties.  Cositecan stabilizes the cleavable complex between topoisomerase I and DNA, resulting in DNA breaks and consequently triggering apoptosis.  Because it is lipophilic, cositecan exhibits enhanced tissue penetration and bio-availability compared to water-soluble camptothecins."}]