[{"from": "human", "value": "Could you give me a brief overview of this molecule? [C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][C@H1][Branch1][=Branch1][C][=Branch1][C][=O][O][N][C][=Branch1][C][=O][C@H1][Branch2][Ring2][Ring2][C][S][=Branch1][C][=O][=Branch1][C][=O][C][C][O][P][=Branch1][C][=O][Branch1][#Branch2][N][Branch1][Ring2][C][C][Cl][C][C][Cl][N][Branch1][Ring2][C][C][Cl][C][C][Cl][N][C][=Branch1][C][=O][C][C][C@@H1][Branch1][=Branch1][C][=Branch1][C][=O][O][N].[Cl]"}, {"from": "gpt", "value": "The molecule is the hydrochloride salt of a modified glutathione analogue with potential antineoplastic activity. Canfosfamide is selectively activated by glutathione S-transferase P1-1 into an alkylating metabolite that forms covalent linkages with nucleophilic centers in tumor cell DNA, which may induce a cellular stress response and cytotoxicity, and decrease tumor proliferation. S-transferase P1-1 is an enzyme that is overexpressed in many human malignancies."}]