[{"from": "human", "value": "Could you give me a brief overview of this molecule? [C][C][=C][Branch1][=N][C][Branch1][=Branch1][C][C][C][Ring1][=Branch1][Branch1][C][C][C][/C][=C][/C][=Branch1][=C][=C][/C][=C][/C][=Branch1][#Branch1][=C][\\C][=Branch1][C][=O][O][/C][/C]"}, {"from": "gpt", "value": "The molecule is a naturally-occurring retinoic acid with potential antineoplastic activity. Isotretinoin binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. This agent also exhibits immunomodulatory and anti-inflammatory responses and inhibits ornithine decarboxylase, thereby decreasing polyamine synthesis and keratinization."}]