[{"from": "human", "value": "Provide a brief overview of this molecule. [C][Branch1][Ring1][C][N][C][Branch1][C][O][Branch1][=Branch2][P][=Branch1][C][=O][Branch1][C][O][O][P][=Branch1][C][=O][Branch1][C][O][O]"}, {"from": "gpt", "value": "The molecule is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid] and [alendronic acid]. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as [ibandronic acid], [zoledronic acid], [minodronic acid], and [risedronic acid] are becoming more popular.  Pamidronic acid was granted FDA approval on 31 October 1991."}]