[{"from": "human", "value": "Provide a description of this molecule. [C][C@@H1][C][O][C][=Branch1][Ring2][=N][Ring1][Branch1][N][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][N][=C][N][=C][Ring1][Branch2][N][C][=C][C][=Branch1][P][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][O][C][C][=N][C][=C][S][Ring1][Branch1][Cl]"}, {"from": "gpt", "value": "The molecule is an orally bioavailable inhibitor of the epidermal growth factor receptor family with potential antineoplastic activity. Varlitinib selectively and reversibly binds to both EGFR (ErbB-1) and Her-2/neu (ErbB-2) and prevents their phosphorylation and activation, which may result in inhibition of the associated signal transduction pathways, inhibition of cellular proliferation and cell death. EGFR and Her-2 play important roles in cell proliferation and differentiation and are upregulated in various human tumor cell types. Due to the dual inhibition of both EGFR and Her-2, this agent may be therapeutically more effective than agents that inhibit EGFR or Her-2 alone."}]