[{"from": "human", "value": "Please give me some details about this molecule. [C][C@H1][/C][=C][\\C][/C][=Branch2][Branch1][Branch1][=C][\\C][C@H1][Branch2][Ring1][S][O][C][=Branch1][C][=O][C][C@@H1][Branch2][Ring1][Branch1][C][Branch1][=C][C][=Branch1][C][=O][C@@H1][Branch1][=Branch1][C@H1][Ring2][Ring1][C][O][C][Branch1][C][C][C][O][/C][=Branch1][N][=C][/C][=N][O][C][=Branch1][Ring2][=C][Ring1][Branch1][C][/C][/C]"}, {"from": "gpt", "value": "The molecule is a third-generation epothilone B analogue with potential anti-mitotic and antineoplastic activites. Iso-fludelone binds to tubulin and induces microtubule polymerization and stabilizes microtubules against depolymerization, which may result in the inhibition of cell division, the induction of G2/M arrest, and apoptosis. Compared to other generations of epothilones, iso-fludelone exhibits increased stability, water solubility, potency, duration of action, tumor penetration as well as reduced toxicity. In addition, this agent is a not a substrate of the P-glycoprotein (P-gp), a multidrug resistance pump often overexpressed in cancer cells."}]