[{"from": "human", "value": "Describe this molecule. [C][C@@H1][Branch2][#Branch2][Branch1][C][=Branch1][C][=O][N][C@H1][C][N][Branch2][Ring2][Branch2][C][C][C@H1][C][C][C@H1][Branch1][Branch2][N][Ring1][Branch1][C][Ring1][O][=O][C][=Branch1][C][=O][N][C][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=C][C][=C][C][=C][Ring1][=Branch1][S][=Branch1][C][=O][=Branch1][C][=O][C][=C][C][=Branch1][=Branch1][=C][C][=C][Ring1][=Branch1][S][=Branch1][C][=O][=Branch1][C][=O][N][C][C][C@H1][C][C][C@H1][Branch2][Ring1][=Branch2][N][Ring1][Branch1][C][=Branch1][C][=O][C@H1][Branch1][Ring2][C][Ring1][N][N][C][=Branch1][C][=O][C@H1][Branch1][C][C][N][C][C][=Branch1][C][=O][N][C][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][C][=C][C][=C][C][=C][Ring1][=Branch1][N][C]"}, {"from": "gpt", "value": "The molecule is a small molecule, second mitochondria-derived activator of caspases (SMAC)-mimetic targeting inhibitor of apoptosis proteins (IAPs) with potential apoptosis-inducing and antineoplastic activities. Upon administration, IAP inhibitor APG-1387 selectively binds to and inhibits the activity of IAPs including X chromosome-linked IAP (XIAP) and cellular IAPs 1 (c-IAP1) and 2 (c-IAP2). This may restore and promote the induction of apoptosis through apoptotic signaling pathways and enhance proteasomal degradation of IAPs. Additionally, APG-1387 may work synergistically with cytotoxic drugs to overcome tumor cell resistance to apoptosis. IAPs are overexpressed by many cancer cell types, suppressing apoptosis by binding and inhibiting active caspases-3, -7 and -9 via their BIR (baculoviral lAP repeat) domains."}]