[{"from": "human", "value": "Provide a brief overview of this molecule. [C][C][C@@H1][Branch2][Ring2][Ring1][C@H1][Branch1][Branch1][N][C][Ring1][=Branch1][C][C][=Branch1][C][=O][C][N][C][=N][C][=C][C][=Branch1][=N][=C][Branch1][=Branch2][C][=C][Ring1][=Branch1][C][Ring1][#Branch2][=O][Cl][Br][O]"}, {"from": "gpt", "value": "The molecule is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis in mice. Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received orphan drug designation from the U.S. Food and Drug Administration in March, 2000."}]