[{"from": "human", "value": "Provide a description of this molecule. [C][C][C][C][Branch1][Branch2][C][Ring1][Branch1][C][=C][Ring1][=Branch1][C][N][C][=C][C][=Branch2][Ring1][#Branch2][=C][Branch1][#C][C][=C][Ring1][=Branch1][S][=Branch1][C][=O][=Branch1][C][=O][N][Ring1][N][S][=Branch1][C][=O][=Branch1][C][=O][N][Cl]"}, {"from": "gpt", "value": "The molecule is less well understood although it may be mediated through its action on carbonic anhydrases in the smooth muscle or through its action on the large-conductance calcium-activated potassium (KCa) channel, also found in the smooth muscle. Cyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension."}]