[{"from": "human", "value": "Provide a brief overview of this molecule. [C][C][Branch2][Branch1][O][C][C][C][=Branch1][Branch1][=C][C][Ring1][=Branch1][C][=C][Branch2][Ring1][=N][C][=C][C][=Branch1][Ring2][=N][Ring1][=Branch1][C][C][C][Branch1][N][O][C][Branch1][Ring2][C][Ring1][=Branch1][Branch1][C][C][C][Branch1][C][C][C][N][C][=Branch1][C][=O][C][=N][C][=C][Branch1][Ring2][N][Ring1][Branch1][C][#N][C]"}, {"from": "gpt", "value": "The molecule is a small molecule and orally available inhibitor of colony-stimulating factor-1 receptor (CSF1R; FMS) with potential antineoplastic activity. Edicotinib blocks the receptor-ligand interaction between FMS and its ligand CSF1, thereby preventing autophosphorylation of FMS. As a result, unphosphorylated FMS can not activate FMS-mediated signaling pathways, thus potentially inhibiting cell proliferation in FMS-overexpressed tumor cells. FMS, a tyrosine kinase receptor, is overexpressed in certain tumor cell types and plays an essential role in macrophage differentiation, recruitment, and activation as well as the regulation of cell proliferation."}]