[{"from": "human", "value": "Provide a brief overview of this molecule. [C][C][N][C][=C][C][=C][Branch2][Ring2][=Branch1][N][C][Ring1][Branch1][=N][C][=C][Ring1][=Branch2][C][N][Branch1][Branch1][C][Ring1][=N][=O][C][=C][Branch1][S][C][=Branch1][O][=C][C][=Branch1][Branch1][=C][Ring1][=Branch1][F][O][C][O][C][F][C][N][C][C][O][C][C][Ring1][=Branch1]"}, {"from": "gpt", "value": "The molecule is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) types 1, 2, and 3 (FGFR1/2/3), with potential antineoplastic activity. Pemigatinib binds to and inhibits FGFR1/2/3, which may result in the inhibition of FGFR1/2/3-related signal transduction pathways. This inhibits proliferation in FGFR1/2/3-overexpressing tumor cells. FGFR, a family of receptor tyrosine kinases upregulated in many tumor cell types, plays a key role in cellular proliferation, migration, and survival."}]