[{"from": "human", "value": "What can you tell me about this molecule? [C][/C][=Branch1][Branch2][=N][\\N][=C][Branch1][C][N][N][/C][=N][/N][=C][Branch1][C][N][N]"}, {"from": "gpt", "value": "The molecule is a guanylhydrazone with potential antineoplastic activity. Mitoguazone competitively inhibits S-adenosyl-L-methionine decarboxylase (SAMD), an enzyme involved in the synthesis of polyamines, resulting in decreased proliferation of tumor cells, antimitochondrial effects, and p53-independent apoptosis. Polyamines, specifically spermine and spermidine, are essential for thymidine kinase production, DNA synthesis, and cell proliferation. (NCI04)"}]