[{"from": "human", "value": "Provide a description of this molecule. [C][=C][N][Branch1][=Branch2][C][=Branch1][C][=O][N][=C][Ring1][#Branch1][C@H1][C@@H1][Branch1][=N][C@@H1][Branch1][=Branch2][C@H1][Branch1][Ring2][O][Ring1][Branch1][C][O][O][O]"}, {"from": "gpt", "value": "The molecule is a synthetic cytidine analogue and a cytidine deaminase inhibitor with anticancer activity. Following metabolic activation by phosphorylation and incorporation into DNA, zebularine inhibits DNA methyltransferase through covalent complex formation between the enzyme and zebularine-substituted DNA, hence resulting in non-specific, genome-wide induction of demethylation including the removal of aberrant methylation of promoter regions of genes critical for normal cellular functions."}]