[{"from": "human", "value": "Could you provide a description of this molecule? [C][S][=Branch1][C][=O][=Branch1][C][=O][N][C][=C][Branch1][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][N+1][=Branch1][C][=O][O-1][O][C][=C][C][=C][C][=C][Ring1][=Branch1]"}, {"from": "gpt", "value": "The molecule is a nonsteroidal arylsulfonamide with anti-inflammatory properties.  Nimesulide inhibits the cyclooxygenase-mediated conversion of arachidonic acid to pro-inflammatory prostaglandins.  Modestly selective for COX-2, this agent binds to the enzyme, thereby inactivating it.  Nimesulide may inhibit some carcinogenic COX-2-related carcinogenic effects on xenobiotic metabolism, apoptosis, immune surveillance and angiogenesis (overexpressed COX-2 in tumor epithelial cells enhances production of vascular growth factors and the formation of capillary-like networks). (NCI04)"}]