[{"from": "human", "value": "Could you give me a brief overview of this molecule? [C][C][C][=C][Branch2][Branch1][Branch1][N][=C][Branch1][N][C][=Branch1][Ring2][=N][Ring1][=Branch1][C][=Branch1][C][=O][N][N][C][=C][C][=Branch2][Ring1][=N][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][N][C][C][C][Branch1][Branch1][C][C][Ring1][=Branch1][N][C][C][N][Branch1][Branch1][C][C][Ring1][=Branch1][C][O][C][N][C][C][C][O][C][C][Ring1][=Branch1].[C][C][C][=C][Branch2][Branch1][Branch1][N][=C][Branch1][N][C][=Branch1][Ring2][=N][Ring1][=Branch1][C][=Branch1][C][=O][N][N][C][=C][C][=Branch2][Ring1][=N][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][N][C][C][C][Branch1][Branch1][C][C][Ring1][=Branch1][N][C][C][N][Branch1][Branch1][C][C][Ring1][=Branch1][C][O][C][N][C][C][C][O][C][C][Ring1][=Branch1].[C][=Branch1][#Branch1][=C][/C][=Branch1][C][=O][O][\\C][=Branch1][C][=O][O]"}, {"from": "gpt", "value": "The molecule is the fumarate salt form of gilteritinib, an orally bioavailable inhibitor of the receptor tyrosine kinases (RTKs) FMS-like tyrosine kinase 3 (FLT3; STK1; FLK2), AXL (UFO; JTK11), anaplastic lymphoma kinase (ALK; CD246), and leukocyte receptor tyrosine kinase (LTK), with potential antineoplastic activity. Upon administration, gilteritinib binds to and inhibits both the wild-type and mutated forms of FLT3, AXL, ALK and LTK. This may result in an inhibition of FLT3-, AXL-, ALK-, and LTK-mediated signal transduction pathways and reduced proliferation in cancer cells that overexpress these RTKs. FLT3, AXL, ALK, and LTK, which are overexpressed or mutated in a variety of cancer cell types, play key roles in tumor cell growth and survival."}]