[{"from": "human", "value": "What can you tell me about this molecule? [C][C@H1][C][C@@H1][C@H1][Branch2][Ring2][#C][C@H1][Branch2][Ring2][#Branch2][C@][Branch1][Ring2][O][Ring1][Branch1][C][C][C@H1][C@@H1][C][C][C][=C][C][=Branch1][C][=O][C][C][C@@][Ring1][#Branch1][Branch1][S][C@H1][Ring1][O][C][C][Ring1][=C][=C][Branch1][Branch1][C][Ring2][Ring1][Ring2][C][C][C][N][C][Ring2][Ring1][=C]"}, {"from": "gpt", "value": "The molecule is a semi-synthetic cyclopamine analogue and an inhibitor of SMO and the Hedgehog (Hh) pathway, with potential antineoplastic activity. Upon administration, smoothened antagonist IPI-609 targets, binds to and inhibits the cell membrane-spanning G-protein coupled receptor SMO, which may result in the suppression of Hh pathway signaling and a decrease in tumor cell proliferation and survival. SMO is activated upon binding of Hh ligand to the cell surface receptor Patched (PTCH); inappropriate activation of Hh signaling and uncontrolled cellular proliferation may be associated with SMO mutations."}]