[{"from": "human", "value": "What can you tell me about this molecule? [C][C@@H1][C][C][C@H1][C][C@@H1][Branch2][Branch2][=N][/C][=Branch2][Branch2][Branch2][=C][/C][=C][/C][=C][/C@H1][Branch2][#Branch1][=C][C][C@H1][Branch2][#Branch1][Branch2][C][=Branch1][C][=O][C@@H1][Branch2][=Branch1][=C][C@@H1][Branch2][=Branch1][=Branch2][/C][=Branch2][=Branch1][Ring2][=C][/C@H1][Branch2][Branch1][=C][C][=Branch1][C][=O][C][C@H1][Branch2][Ring1][P][O][C][=Branch1][C][=O][C@@H1][C][C][C][C][N][Ring1][=Branch1][C][=Branch1][C][=O][C][=Branch1][C][=O][C@@][Ring2][Ring2][Branch2][Branch1][Branch1][O][Ring2][Ring2][=Branch1][O][C@H1][Branch1][C][C][C][C@@H1][C][C][C@H1][Branch1][=Branch2][C@@H1][Branch1][Ring2][C][Ring1][=Branch1][O][C][O][C][/C][O][O][C][C][C][/C][O][C]"}, {"from": "gpt", "value": "The molecule is macrocyclic antibiotic with potent immunosuppressive activity that is used alone or in combination with calcineurin inhibitors and corticosteroids to prevent cellular rejection after renal transplantation. Sirolimus therapy can be associated with mild serum enzyme elevations and it has been linked to rare instances of clinically apparent cholestatic liver injury."}]