[{"from": "human", "value": "What can you tell me about this molecule? [C][N][C][C][N][C@H1][Branch1][Ring2][C][Ring1][=Branch1][C][=C][C][=C][C][=C][Ring1][=Branch1][C][C][=C][Ring1][N][N][=C][C][=C][Ring1][=Branch1]"}, {"from": "gpt", "value": "The molecule is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology. This includes inverse agonist activity of H1 and 5-HT2 receptors and antagonism of \u03b12-adrenergic receptors. Merck has terminated its internal clinical development program for esmirtazapine as of March 2010."}]