[{"from": "human", "value": "What can you tell me about this molecule? [C][C][=C][C][=C][Branch1][Ring2][N][Ring1][Branch1][C][=C][C][=Branch1][Branch1][=C][Ring1][#Branch1][F][O][C][=N][C][=N][N][C][Ring1][=Branch1][=C][Branch1][=C][C][=Branch1][Ring2][=C][Ring1][Branch1][O][C][C@@H1][Branch1][C][C][O][C]"}, {"from": "gpt", "value": "The molecule is a pyrrolotriazine-based compound and an inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) with potential antineoplastic activity. BMS-540215 specifically targets and binds strongly to human VEGFR-2, a tyrosine kinase receptor and pro-angiogenic growth factor expressed almost exclusively on vascular endothelial cells. Blockade of VEGFR-2 by this agent may lead to an inhibition of VEGF-stimulated endothelial cell migration and proliferation, thereby inhibiting tumor angiogenesis."}]