[{"from": "human", "value": "Describe this molecule. [C][C@@H1][Branch1][O][C][=Branch1][C][=O][O][C][Branch1][C][C][C][N][P@][=Branch1][C][=O][Branch2][Ring2][Ring1][O][C][C@@H1][C@H1][Branch2][Ring1][O][C@@][Branch2][Ring1][Ring1][C@@H1][Branch1][Ring2][O][Ring1][Branch1][N][C][=C][C][=Branch1][C][=O][N][C][Ring1][#Branch1][=O][Branch1][C][C][F][O][O][C][=C][C][=C][C][=C][Ring1][=Branch1]"}, {"from": "gpt", "value": "The molecule is an orally available nucleotide prodrug and a hepatitis C virus (HCV) NS5B polymerase inhibitor with potential HCV inhibiting activity. Upon oral administration, sofosbuvir is metabolized to 2'-deoxy-2'-alpha-fluoro-beta-C-methyluridine-5'-monophosphate, which is then converted into the active triphosphate nucleotide that inhibits the NS5B polymerase, thereby preventing viral replication. The HCV NS5B protein, an RNA-dependent RNA polymerase, is essential for the replication of the viral HCV RNA genome."}]