[{"from": "human", "value": "What can you tell me about this molecule? [C][C@H1][Branch1][O][C][N][C@@H1][Ring1][Branch1][C][=Branch1][C][=O][O][O]"}, {"from": "gpt", "value": "The molecule is a nonessential amino acid derivative formed during post-translational protein modification through hydroxylation of the amino acid proline by the enzyme prolyl hydroxylase which requires vitamin C as a co-factor. Hydroxyproline is a major component of the protein collagen and plays a key role in the stability of the collagen triple helix. It can be used as an indicator to determine the amount of collagen. Increased hydroxyproline levels in the urine and/or serum are normally associated with degradation of connective tissue. Vitamin C deficiency decreases the conversion of proline to hydroxyproline, which leads to reduced collagen stability."}]