[{"from": "human", "value": "Could you give me a brief overview of this molecule? [C][C@H1][C][C][C][C@@][Branch2][Branch1][#Branch2][C@@H1][Branch1][Ring2][O][Ring1][Ring1][C][C@H1][Branch2][Ring1][S][N][C][=Branch1][C][=O][C][C@@H1][Branch2][Ring1][Branch1][C][Branch1][=C][C][=Branch1][C][=O][C@@H1][Branch1][=Branch1][C@H1][Ring2][Ring1][Ring1][O][C][Branch1][C][C][C][O][/C][=Branch1][N][=C][/C][=C][S][C][=Branch1][Ring2][=N][Ring1][Branch1][C][/C][C]"}, {"from": "gpt", "value": "The molecule is a macrocycle that is a lactam analogue of epothilone B. Binds directly to beta-tubulin subunits on microtubules, leading to suppression of microtubule dynamics. It has a role as an antineoplastic agent and a microtubule-destabilising agent. It is a member of 1,3-thiazoles, a beta-hydroxy ketone, a lactam, a macrocycle and an epoxide."}]