[{"from": "human", "value": "Could you provide a description of this molecule? [C][C][Branch1][C][C][C][C@@H1][Branch2][Ring1][=C][C][=Branch1][C][=O][N][C@@H1][Branch1][#Branch2][C][C][C][C][N][C][Ring1][Branch1][=O][C][Branch1][C][O][S][=Branch1][C][=O][=Branch1][C][=O][O][N][C][=Branch1][C][=O][O][C][C][=C][C][=C][C][=C][Ring1][=Branch1]"}, {"from": "gpt", "value": "The molecule is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells. The compound is known as a direct acting antiviral (DAA) for coronaviruses, and was initially developed using structure-guided design to combat MERS-Cov infections. In addition, GC-376 displays potent activity against various coronaviruses such as feline, ferret, and mink Mpro coronavirus. A prodrug of [GC-373], GC-376 has recently been used to test inhibition of SARS-Cov-2 Mpro in vitro, and results show potent inhibition of this target. These results suggest that GC-376, and its metabolites may have therapeutic potential for Covid-19."}]