[{"from": "human", "value": "What can you tell me about this molecule? [C][C][=C][Branch2][Ring2][Ring2][N][N][=C][Ring1][Branch1][C][=Branch1][C][=O][N][C][=C][N][=C][C][=Branch1][Ring2][=C][Ring1][=Branch1][C][=C][Branch1][Ring2][N][Ring1][=Branch1][C][=C][C][=C][C][=C][Ring1][=Branch1][C]"}, {"from": "gpt", "value": "The molecule is an orally bioavailable protein tyrosine kinase inhibitor of mutated forms of the tumor-associated antigen mast/stem cell factor receptor c-Kit (SCFR), with potential antineoplastic activity. Upon oral administration, bezuclastinib binds to and inhibits specific c-Kit mutants. This may result in an inhibition of tumor cell proliferation in cancer cell types that overexpress these c-Kit mutations. c-Kit, a transmembrane protein and receptor tyrosine kinase, is overexpressed in solid tumors and hematological malignancies; it plays a key role in the regulation of cell differentiation and proliferation."}]