[{"from": "human", "value": "Please give me some details about this molecule. [C][=C][C][=Branch1][C][=O][N][C][C][C][C@H1][Branch1][Ring2][C][Ring1][=Branch1][N][C][=N][C][=N][C][=Branch2][Ring1][=N][=C][Ring1][=Branch1][C][=Branch1][Ring2][=N][Ring1][=Branch2][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][O][C][=C][C][=C][C][=C][Ring1][=Branch1][N]"}, {"from": "gpt", "value": "The molecule is an oral inhibitor of Bruton\u2019s tyrosine kinase that is used in the therapy of refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Ibrutinib has not been associated with serum enzyme elevations during therapy, but has been linked to rare cases of clinically apparent acute liver injury and to reactivation of hepatitis B."}]