[{"from": "human", "value": "Provide a brief overview of this molecule. [C][C][Branch1][C][C][Branch1][C][C][C][Branch1][C][C][Branch2][Branch1][Ring2][C@H1][C][C@@][C][C][C@][Ring1][=Branch1][Branch2][Ring2][#Branch1][C][C@@][Ring1][=Branch1][C][C][N][Branch2][Ring1][#Branch1][C@@H1][Ring1][#Branch2][C][C][=C][Ring1][Branch2][C][=Branch1][=Branch2][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][O][O][Ring1][#C][C][C][C][C][Ring1][Ring1][O][C][O]"}, {"from": "gpt", "value": "The molecule is a derivative of the opioid alkaloid thebaine that is a more potent (25 - 40 times) and longer lasting analgesic than morphine. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use. "}]