[{"from": "human", "value": "Describe this molecule. [C][=C][C][=Branch2][Ring2][=Branch2][=C][C][=C][Ring1][=Branch1][C][C@@H1][Branch1][#C][C][=Branch1][C][=O][N][C][C][C][C][N][C][C][C][N][N][C][=Branch1][C][=O][C][C][Branch1][Ring2][O][Ring1][Ring1][C][=Branch1][C][=O][O][O]"}, {"from": "gpt", "value": "The molecule is an epoxide which is a carboxamide obtained by the formal condensation of one of the carboxy groups of oxirane-2,3-dicarboxylic acid with N-{4-[(3-aminopropyl)amino]butyl}-L-tyrosinamide. It is a natural product, isolated from Gliocladium sp. F-2665. TMC-52B acts as an inhibitor of cysteine proteinases, particularly cathepsin B (EC 3.4.22.1), cathepsin L (EC 3.4.22.15), and papain (EC 3.4.22.2); IC50 values are 200 nM, 10 nM, and 7 nM, respectively. The epoxide group has trans configuration but its exact stereochemistry is uncertain: it is either (2R,3R) or (2S,3S). It has a role as a metabolite, an antimicrobial agent, a cathepsin B inhibitor, a cathepsin L (EC 3.4.22.15) inhibitor and an EC 3.4.22.2 (papain) inhibitor. It is an epoxide, a monocarboxylic acid, a member of phenols, a primary amino compound and a secondary amino compound."}]