[{"from": "human", "value": "What can you tell me about this molecule? [C][=C][C][=Branch1][=Branch1][=C][N][=C][Ring1][=Branch1][C][C][=C][N][C][=C][Ring1][Branch1][N][=C][Branch1][=Branch1][N][C][Ring1][=Branch1][=O][N]"}, {"from": "gpt", "value": "The molecule is a pyrimidine analogue and purine nucleoside phosphorylase inhibitor with immunosuppressive and antineoplastic properties. Peldesine inhibits purine nucleoside phosphorylase (PNP) that plays a pivotal role in T-cell proliferation and is responsible for the catalysis of the reversible phosphorolytic cleavage of purine ribonucleosides and 2'-deoxyribonucleosides. Inhibition of PNP results in accumulation of dGTP and the subsequent failure of DNA synthesis. This agent maybe used in T-cell related autoimmune diseases including psoriasis, rheumatoid arthritis and Crohn s disease and T-cell cancers"}]