[{"from": "human", "value": "Provide a brief overview of this molecule. [C][O][C][=C][Branch2][Ring2][Branch1][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][C][S][=Branch1][C][=O][=Branch1][C][=O][/C][=C][/C][=C][Branch1][=N][C][=C][Branch1][#Branch1][C][=C][Ring1][=Branch1][O][C][O][C][O][C][N][C][C][=Branch1][C][=O][O]"}, {"from": "gpt", "value": "The molecule is a synthetic benzyl styryl sulfone analogue and Ras mimetic, with potential antineoplastic activity. Upon administration, rigosertib targets and binds to Ras-binding domain (RBD) found in many Ras effector proteins, including Raf kinase and phosphatidylinositol 3-kinase (PI3K). This prevents Ras from binding to its targets and inhibits Ras-mediated signaling pathways, including Ras/Raf/Erk, Ras/CRAF/polo-like kinase1 (Plk1), and Ras/ PI3K/Akt signaling pathways. This induces cell cycle arrest and apoptosis and inhibits proliferation in a variety of susceptible tumor cells."}]