[{"from": "human", "value": "Could you provide a description of this molecule? [C][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C@H1][Ring1][=Branch2][N][C][=C][C][=C][N][Branch1][=Branch2][C][Ring1][Branch1][=N][C][=N][Ring1][=Branch2][C@@H1][C][C@H1][Branch1][Branch2][C@H1][Branch1][Ring2][C][Ring1][Branch1][O][C][O][S][=Branch1][C][=O][=Branch1][C][=O][N]"}, {"from": "gpt", "value": "The molecule is a pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine which is substituted by a (1S)-2,3-dihydro-1H-inden-1-ylnitrilo group at position 4 and by a (1S,3S,4S)-3-hydroxy-4-[(sulfamoyloxy)methyl]cyclopentyl group at position 7. It is a potent and selective NEDD8-activating enzyme inhibitor with an IC50 of 4.7 nM, and currently under clinical investigation for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndromes. It has a role as an apoptosis inducer and an antineoplastic agent. It is a pyrrolopyrimidine, a secondary amino compound, a member of cyclopentanols, a sulfamidate and a member of indanes."}]