[{"from": "human", "value": "Describe this molecule. [C][C][=N][C][=C][Branch2][Branch1][Branch2][C][=C][Branch2][Ring2][=C][C][=C][C][=Branch1][Ring2][=C][Ring1][=Branch1][C][N][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][C][=Branch1][C][=O][N][Branch1][Ring2][C][Ring1][Branch2][C@@H1][Branch1][Branch2][C][C][C][=Branch1][C][=O][O][C][=Branch1][C][=O][O][C][=C][Ring2][Ring1][#C][C][=Branch1][C][=O][N][Ring2][Ring2][Ring2]"}, {"from": "gpt", "value": "The molecule is a liposome-encapsulated formulation of the benzoquinazoline folate analog OSI-7904 with antineoplastic activity. As a thymidylate synthase inhibitor, OSI-7904 noncompetitively binds to thymidylate synthase, resulting in inhibition of thymine nucleotide synthesis and DNA replication. Liposome encapsulation improves the efficacy and increases the half-life of OSI-7904. (NCI04)"}]