[{"from": "human", "value": "Provide a brief overview of this molecule. [C][C][C][=N][C][=Branch2][Branch1][Branch2][=C][Branch2][Ring2][#C][N][Ring1][Branch1][C][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][O][C][=Branch1][Branch1][=C][Ring1][#Branch1][Br][C][=C][C][=C][C][=C][Ring1][=Branch1][N][S][=Branch1][C][=O][=Branch1][C][=O][C][Branch1][C][F][Branch1][C][F][F][C][=Branch1][C][=O][N][C][C][C][Ring1][Ring1]"}, {"from": "gpt", "value": "The molecule is an AT1 receptor antagonist. It is based on medications of losartan's prototypical chemical structure. The mode of (functional) AT1 receptor antagonism has been characterized as insurmountable/noncompetitive for saprisartan.  It is very likely that slow dissociation kinetics from the AT1 receptor underlie insurmountable antagonism."}]