[{"from": "human", "value": "What can you tell me about this molecule? [C][C][Branch1][C][C][N][=C][Branch1][C][N][N][=C][Branch1][C][N][N][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][Cl].[Cl]"}, {"from": "gpt", "value": "The molecule is the hydrochloride salt form of proguanil, a synthetic biguanide derivative of pyrimidine and an folate antagonist with antimalarial property. Upon hydrolysis, proguanil is converted to its active cyclic triazine metabolite, cycloguanil, by a cytochrome P450 dependent reaction. Cycloguanil selectively inhibits the bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) of plasmodium parasite, thereby disrupting deoxythymidylate synthesis and ultimately blocking DNA and protein synthesis in the parasite."}]