[{"from": "human", "value": "Provide a brief overview of this molecule. [C][C][C][C][C][C][C][C][=Branch1][C][=O][O][C@H1][C@H1][C][=Branch2][Ring1][Ring1][=C][Branch1][#C][C@@H1][Ring1][Branch1][O][C][=Branch1][C][=O][/C][=Branch1][Ring1][=C][\\C][/C][C][C@H1][C@][Branch2][Ring1][=Branch2][C@H1][Branch1][=C][C][C@][Ring1][P][Branch1][C][C][O][C][=Branch1][C][=O][C][O][C][=Branch1][C][=O][C][C][C][Branch1][S][C@][Branch1][=Branch2][C][=Branch1][C][=O][O][Ring2][Ring1][Ring2][Branch1][C][C][O][O]"}, {"from": "gpt", "value": "The molecule is an organic heterotricyclic compound that is a hexa-oxygenated 6,7-guaianolide isolated fron the roots of Thapsia garganica L., Apiaceae. A potent skin irritant, it is used in traditional medicine as a counter-irritant. Thapsigargin inhibits Ca(2+)-transporting ATPase mediated uptake of calcium ions into sarcoplasmic reticulum and is used in experimentation examining the impacts of increasing cytosolic calcium concentrations. It has a role as an EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor and a calcium channel blocker. It is a sesquiterpene lactone, an organic heterotricyclic compound and a butyrate ester."}]