[{"from": "human", "value": "Provide a brief overview of this molecule. [C][C][Branch1][C][C][C][=C][Branch2][Ring1][P][C][=Branch2][Ring1][C][=C][Branch1][N][C][=Branch1][Ring2][=N][Ring1][=Branch1][C][Branch1][C][C][C][C][O][C][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][F][/C][=C][/C@H1][Branch1][N][C][C@H1][Branch1][#Branch1][C][C][=Branch1][C][=O][O][O][O]"}, {"from": "gpt", "value": "The molecule is a synthetic lipid-lowering agent. Cerivastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. This agent lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing major histocompatibility complex II on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. Muscle toxicity (myopathy and rhabdomyolysis) precludes the clinical use of this agent."}]