[{"from": "human", "value": "Describe this molecule. [C][C][Branch2][Branch1][C][C][=C][Branch2][Ring1][O][C][=C][Branch1][Ring2][S][Ring1][Branch1][C][=N][C][=Branch1][=Branch1][=N][C][=C][Ring1][=Branch1][N][C][=C][C][=N][N][Ring1][Branch1][C][C][=Branch1][C][=O][N][Ring2][Ring1][=Branch1][C][C][N][C][C][O][C][C][Ring1][=Branch1][C]"}, {"from": "gpt", "value": "The molecule is an orally available inhibitor of extracellular signal-regulated kinase (ERK) 1 and 2, with potential antineoplastic activity. Upon oral administration, temuterkib inhibits both ERK 1 and 2, thereby preventing the activation of mitogen-activated protein kinase (MAPK)/ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The MAPK/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival."}]