[{"from": "human", "value": "Please give me some details about this molecule. [C][C][=Branch1][C][=O][O].[C][C][C][N][Branch1][Ring2][C][Ring1][Branch1][/C][=Branch2][Ring1][O][=N][/C][=Branch2][Ring1][Branch1][=N][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][O][C][Branch1][C][F][Branch1][C][F][F][N][/N]"}, {"from": "gpt", "value": "The molecule is an orally bioavailable biguanide compound and mitochondrial oxidative phosphorylation (OxPhos) inhibitor, with potential antineoplastic activity. Upon administration, IM156 inhibits oxidative phosphorylation, decreases mitochondrial function, prevents tumor cell metabolism and deprives tumor cells of energy, thereby preventing tumor cell proliferation. Mitochondrial OxPhos is overactivated in cancer cells and plays a key role in tumor cell proliferation. Drug resistant tumor cells are very susceptible to decreased mitochondrial OxPhos as they cannot easily compensate for the decrease in mitochondrial function by increasing glycolysis."}]