[{"from": "human", "value": "Describe this molecule. [C][C][O][C][=C][Branch2][Ring2][N][C][=C][C][=Branch1][Ring2][=C][Ring1][=Branch1][N][=C][N][=C][Ring1][#Branch1][N][C][=C][C][=Branch2][Ring1][=Branch1][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][O][C][=C][C][=N][C][=N][N][Ring1][Branch1][C][=C][Ring1][=Branch2][C][N][C][=Branch1][C][=O][/C][=Branch1][#Branch2][=C][/C@H1][C][C][C][N][Ring1][Branch1][C][/F]"}, {"from": "gpt", "value": "The molecule is an orally bioavailable, irreversible inhibitor of the receptor tyrosine kinase human epidermal growth factor receptor 2 (HER2; ErbB2; HER-2), with potential antineoplastic activity. Upon oral administration, HER2 inhibitor SPH5030 selectively binds to and inhibits the activity of wild-type and various HER2 mutants. This prevents HER2-mediated signaling and may lead to cell death in HER2-expressing tumor cells. HER2, a receptor tyrosine kinase overexpressed on a variety of tumor cell types, plays an important role in tumor cell proliferation and tumor vascularization."}]