[{"from": "human", "value": "Provide a brief overview of this molecule. [C][C@@H1][C][C][C@H1][Branch2][Ring2][Ring2][C@@H1][Branch1][Ring2][C][Ring1][=Branch1][C][=Branch1][C][=O][N][C][=C][Branch1][O][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][O][C][N][Branch1][Branch1][C][Ring1][O][=O][C][C][N][C][Branch1][C][C][C].[Cl]"}, {"from": "gpt", "value": "The molecule is an enteric-coated orally bioavailable formulation of the hydrochloride salt of a small-molecule agonist for transient receptor potential melastatin member 8 (TRPM8 or Trp-p8) with potential antineoplastic activity. The active ingredient in enteric-coated TRPM8 agonist D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. This agent may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH. TRPM8 is a transmembrane calcium channel protein that is normally expressed in prostate cells and appears to be overexpressed in benign prostatic hyperplasia (BPH) and in prostate cancer."}]