[{"from": "human", "value": "Could you give me a brief overview of this molecule? [C][=C][C][=Branch1][C][=O][N][C][C][N][Branch1][Branch1][C][C][Ring1][=Branch1][C][=N][C][=N][C][=C][Branch2][Ring1][#Branch2][C][=Branch1][O][=C][Branch1][#Branch1][C][=C][Ring1][=Branch1][Ring1][#Branch2][Cl][C][=C][Branch1][Branch2][C][=C][C][=C][Ring1][=Branch1][F][O][F]"}, {"from": "gpt", "value": "The molecule is a qinazoline derivative carrying chloro and fluoro substituents at positions 6 and 8 respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. A potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor, it inhibits the protein coding gene KRAS (Kirsten rat sarcoma virus) with high potency in cells and animals. It has a role as an inhibitor, an antiviral agent and an antineoplastic agent."}]