[{"from": "human", "value": "Describe this molecule. [C][C][C@@H1][C@@H1][C][N][Branch2][Ring2][=Branch2][C@@H1][Ring1][Branch1][C][=Branch1][C][=O][N][C@@][Branch1][#Branch2][C][C@H1][Ring1][Ring1][C][Branch1][C][F][F][C][=Branch1][C][=O][N][S][=Branch1][C][=O][=Branch1][C][=O][C][Branch1][Branch1][C][C][Ring1][Ring1][C][C][=Branch1][C][=O][C@@H1][Branch2][Ring2][S][N][C][=Branch1][C][=O][O][C@@H1][C][C@H1][Ring1][Ring1][C][C][C][C][C][Branch2][Ring1][=Branch2][C][=N][C][=C][Branch1][O][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][O][C][N][=C][Ring1][N][O][Ring2][Branch1][Ring1][Branch1][C][F][F][C][Branch1][C][C][Branch1][C][C][C]"}, {"from": "gpt", "value": "The molecule is an orally bioavailable inhibitor of the hepatitis C virus (HCV) non-structural protein 3/non-structural protein 4A (NS3/NS4A) serine protease, with antiviral activity. Upon administration, voxilaprevir binds to the HCV NS3/NS4A serine protease and prevents NS3/NS4A protease-mediated polyprotein maturation. This disrupts both the processing of viral proteins and the formation of the viral replication complex, thereby preventing viral replication and function. NS3, a serine protease, is essential for the proteolytic cleavage of multiple sites within the HCV polyprotein and plays a key role during HCV ribonucleic acid (RNA) replication. NS4A is an activating factor for NS3. HCV is a small, enveloped, single-stranded RNA virus belonging to the Flaviviridae family; HCV infection is associated with the development of hepatocellular carcinoma (HCC)."}]