[{"from": "human", "value": "Provide a brief overview of this molecule. [C][Branch2][Ring1][P][C@@H1][C@H1][Branch2][Ring1][O][C@H1][Branch2][Ring1][=Branch1][C@@H1][Branch1][Ring2][O][Ring1][Branch1][C][=N][N][C][=Branch1][Branch1][=C][Ring1][Branch1][O][C][=Branch1][C][=O][N][O][O][O]"}, {"from": "gpt", "value": "The molecule is a nucleoside analog.  Pyrazofurin potently inhibits orotidine 5'-monophosphate (OMP) decarboxylase, thereby interfering with de novo synthesis of uridine nucleotides and resulting in cytotoxicity.  This agent also causes a rapid depletion of the pyrimidine deoxynucleotide pool, thereby inhibiting DNA synthesis and cell replication. (NCI04)"}]