[{"from": "human", "value": "Provide a brief overview of this molecule. [C][N][C][=C][Branch1][Branch1][C][=N][Ring1][Branch1][C][=N][N][C][=Branch2][Ring1][#Branch1][=N][N][=C][Ring1][Branch1][S][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][N][=C][C][=C][Ring1][Branch2][C][=C][Ring2][Ring1][Ring2]"}, {"from": "gpt", "value": "The molecule is an orally bioavailable small molecule, c-Met inhibitor with potential antineoplastic activity. MET receptor tyrosine kinase inhibitor SGX523 specifically binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of hepatocyte growth factor (HGF) and disrupting the MET signaling pathway; this agent may induce cell death in tumor cells expressing c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays an important role in tumor cell proliferation, survival, invasion, and metastasis, and in tumor angiogenesis."}]