[{"from": "human", "value": "Provide a brief overview of this molecule. [C][Branch1][=Branch2][P][=Branch1][C][=O][Branch1][C][O][O][Branch1][=Branch2][P][=Branch1][C][=O][Branch1][C][O][O][Branch1][C][Cl][Cl]"}, {"from": "gpt", "value": "The molecule is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid]. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. clodronate\u2019s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid].  Clodronic acid is not FDA approved, but is approved in Canada."}]