[{"from": "human", "value": "Provide a description of this molecule. [C][O][C][=C][C][=C][Branch1][O][C][=C][N][=C][Ring1][=Branch1][C][=C][Ring1][#Branch2][C@H1][Branch1][#C][C@@H1][C][C@@H1][C][C][N][Ring1][=Branch1][C][C@@H1][Ring1][=Branch1][C][=C][O]"}, {"from": "gpt", "value": "The molecule is a quinidine alkaloid isolated from the bark of the cinchona tree. Quinine has many mechanisms of action, including reduction of oxygen intake and carbohydrate metabolism; disruption of DNA replication and transcription via DNA intercalation; and reduction of the excitability of muscle fibers via alteration of calcium distribution.  This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)"}]