[{"from": "human", "value": "What can you tell me about this molecule? [C][N][Branch1][C][C][C][C][N][C][=Branch1][C][=O][C][O][C][=C][C][C][=C][Branch2][=Branch1][#Branch2][C][=Branch1][=Branch1][=C][C][=C][Ring1][=Branch1][C][C][=C][Branch2][Ring2][=C][C][=Branch1][=Branch1][=C][C][=C][Ring1][=Branch1][C][C][=C][C][=C][C][=Branch2][Ring1][C][=C][Ring1][=Branch1][O][C][C][=Branch1][C][=O][N][C][C][N][Branch1][C][C][C][C][C][Ring2][Ring2][Ring1][=C][C][=C][Ring2][Ring2][Branch1][O][C][C][=Branch1][C][=O][N][C][C][N][Branch1][C][C][C][O][C][C][=Branch1][C][=O][N][C][C][N][Branch1][C][C][C]"}, {"from": "gpt", "value": "The molecule is a calixarene-based compound and galectin-1 (Gal-1) inhibitor with potential anti-angiogenic and antineoplastic activities. Upon subcutaneous administration, galectin-1 inhibitor OTX008 binds Gal-1 which leads to Gal-1 oxidation and proteasomal degradation, through an as of yet not fully elucidated mechanism, and eventually downregulation of Gal-1. This decreases tumor cell growth and inhibits angiogenesis. Gal-1, a multifunctional carbohydrate-binding protein, is often overexpressed on tumor cells and plays a key role in cancer cell proliferation, apoptosis, tumor angiogenesis and evasion of immune responses."}]