[{"from": "human", "value": "Provide a brief overview of this molecule. [C][C][C][C][Branch1][Branch1][C][C][Ring1][=Branch1][C][=Branch1][C][=O][N][Branch1][Branch2][C][=Branch1][C][=O][N][Ring1][=Branch2][C][C][N][Branch1][Ring2][C][C][Cl][C][C][Cl]"}, {"from": "gpt", "value": "The molecule is a bifunctional nitrogen alkylating agent with antineoplastic activity and lipophilic properties. Containing a lipophilic hydantoin group that serves as a carrier to cross the blood brain barrier, spiromustine forms covalent linkages with nucleophilic centers in DNA, causing depurination, base-pair miscoding, strand scission, and DNA-DNA cross-linking, which may result in cytotoxicity. (NCI04)"}]