[{"from": "human", "value": "Could you give me a brief overview of this molecule? [C][C][C@H1][Branch1][C][C][C@@H1][C@H1][Branch2][Branch2][O][C][=C][C@@][Branch1][Ring2][O][Ring1][=Branch1][C][C@@H1][C][C@H1][Branch1][Ring2][O][Ring1][#Branch1][C][/C][=C][Branch2][#Branch1][Ring1][/C@H1][Branch2][Ring2][Branch2][C@H1][Branch2][Ring2][Ring1][/C][=C][/C][=C][\\C][O][C@H1][C@@][/-Ring1][Branch1][Branch2][Ring1][Branch1][C@@H1][Branch1][#Branch2][C][=C][Branch1][Branch1][C@H1][Ring1][=Branch1][O][C][C][=Branch1][C][=O][O][Ring2][Ring1][#Branch2][O][C][O][C@H1][C][C@@H1][Branch2][Ring1][#C][C@H1][Branch1][Branch2][C@@H1][Branch1][Ring2][O][Ring1][=Branch1][C][O][C@H1][C][C@@H1][Branch1][=N][C@H1][Branch1][Branch2][C@@H1][Branch1][Ring2][O][Ring1][=Branch1][C][N][C][O][C][O][C][\\C][C]"}, {"from": "gpt", "value": "The molecule are a series of macrocyclic lactone derivatives with potent anthelmintic properties. A commonly used therapy in recent times has been based on oral or parenteral administration of avermectins, which are macrocyclic lactones produced by fermentation of various, carefully prepared laboratory broths using the soil micro-organism Streptomyces avermitilis. They show activity against a broad range of nematodes and arthropod parasites of domestic animals at dose rates of 300 microgram/kg or less. Unlike the macrolide or polyene antibiotics, they lack significant antibacterial or antifungal activity. (L829)"}]