[{"from": "human", "value": "Please give me some details about this molecule. [C][C][N][C][=Branch1][C][=O][C][N][C][=N][C][=C][Branch1][#Branch1][N][=C][Ring1][=Branch1][Ring1][O][C][=C][Branch1][S][N][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][C][=N][C][=N][N][Ring1][Branch1][C]"}, {"from": "gpt", "value": "The molecule is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR), with potential antineoplastic activity. CC-115 binds to and inhibits the activity of DNA-PK and both raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2), which may lead to a reduction in cellular proliferation of cancer cells expressing DNA-PK and TOR. DNA-PK, a serine/threonine kinase and a member of the PI3K-related kinase subfamily of protein kinases, is activated upon DNA damage and plays a key role in repairing double-stranded DNA breaks via the DNA nonhomologous end joining (NHEJ) pathway; mTOR, a serine/threonine kinase that is upregulated in a variety of tumors, plays an important role downstream in the PI3K/Akt/mTOR signaling pathway."}]