[{"from": "human", "value": "Provide a brief overview of this molecule. [C][S][C][C][C][Branch2][Ring2][Ring1][C][=Branch1][C][=O][N][C@][Branch2][Ring1][Branch1][C][S][=Branch1][C][=O][=Branch1][C][=O][C@@H1][C@H1][Ring1][#Branch1][C@H1][Ring1][Ring1][C][=Branch1][C][=O][O][C][=Branch1][C][=O][O][N]"}, {"from": "gpt", "value": "The molecule is an investigational drug from Lilly, which is being developed as a new treatment option for schizophrenia. LY2140023 is an oral \"prodrug,\" meaning it is devoid of intrinsic biological activity and, once administered, is metabolized to provide the active mGlu2/3 receptor agonist called LY404039. Most currently approved antipsychotic medications work by affecting the neurotransmitters dopamine or serotonin. For LY2140023, the active substance, LY404039, is thought to work by reducing the presynaptic release of another neurotransmitter, glutamate, in brain regions where mGlu2/3 receptors are expressed. Further studies are planned or are ongoing to learn more about the safety and effectiveness, including determining an optimal therapeutic dose for LY2140023."}]