[{"from": "human", "value": "Describe this molecule. [C][=C][C][=Branch1][#Branch2][=C][Branch1][=Branch1][C][=C][Ring1][=Branch1][I][F][N][C][=C][Branch1][#Branch1][C][=C][N][=C][Ring1][=Branch1][C][=Branch1][C][=O][N][C][C@@H1][Branch1][Ring1][C][O][O].[Cl]"}, {"from": "gpt", "value": "The molecule is the hydrochloride salt form of pimasertib, an orally bioavailable small-molecule inhibitor of mitogen activated protein kinase kinases 1 (MEK1) and 2 (MEK2), with potential antineoplastic activity. Upon oral administration, pimasertib selectively binds to and inhibits the activity of MEK1 and 2, thereby preventing the activation of MEK1/2-dependent effector proteins and transcription factors. This results in the inhibition of growth factor-mediated cell signaling and tumor cell proliferation. MEK1/2 (MAP2K1/K2) are dual-specificity threonine/tyrosine kinases that play key roles in the activation of the RAS/RAF/MEK/ERK pathway and are often upregulated in a variety of tumor cell types."}]