[{"from": "human", "value": "What can you tell me about this molecule? [C][C][C][=Branch1][C][=N][N][Branch1][Ring2][C][Ring1][=Branch1][C][C][=C][Branch1][=N][C][=Branch1][C][=O][N][C][=Branch1][C][=O][N][Ring1][Branch2][Cl]"}, {"from": "gpt", "value": "The molecule is a thymidine phosphorylase inhibitor. It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. The main function of Tipiracil in TAS-102 is to increase trifluridine bioavailability by inhibiting its catabolism. TAS-102 is indicated for the treatment of metastatic colorectal cancer which has been previously treated with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, or with an anti-VEGF or anti-EGFR therapy."}]