[{"from": "human", "value": "What can you tell me about this molecule? [C][C@H1][Branch1][=Branch2][C][C][C][C][Branch1][C][C][C][C@H1][C][C][=Branch1][C][=O][C][=C][C][C][C@H1][C][C@H1][Branch2][Ring1][Branch1][C][C][C@@][Ring1][=Branch1][Branch1][=N][C@H1][Ring1][#Branch2][C][C][C@][Ring2][Ring1][C][Ring1][=C][C][C][O]"}, {"from": "gpt", "value": "The molecule is an antilipidemic agent based on the carbon skeleton of cholesterol. Colestolone targets sterol regulatory element binding protein (SREBP) which reduces the transcription of the 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) gene, the rate-limiting enzyme in the sterol pathway. Colestolone is also metabolized by cells into polar sterols, which are known to inhibit HMGCR enzymatic activity."}]