[{"from": "human", "value": "What can you tell me about this molecule? [C][C@@H1][C][C@H1][C@@H1][C][C][C][=C][C][=Branch1][C][=O][C][=C][C@@][Ring1][#Branch1][Branch2][Ring2][#Branch1][C@][Ring1][O][Branch2][Ring1][S][C@H1][Branch2][Ring1][O][C][C@@][Ring1][#C][Branch2][Ring1][Ring1][C@][Ring2][Ring1][C][Branch1][N][C][=Branch1][C][=O][C][O][C][=Branch1][C][=O][C][O][C][O][F][C]"}, {"from": "gpt", "value": "The molecule is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions. Developed in 1957, dexamethasone is structurally similar to other corticosteroids such as [hydrocortisone] and [prednisolone]. Dexamethasone acetate has largely been replaced by [dexamethasone] phosphate and continues to be administered for a large variety of inflammatory conditions.  Recently, dexamethasone has been a drug of interest in the treatment of COVID-19. In a June 16 2020 press release highlighting early results of a clinical trial, Randomized Evaluation of COVID-19 Therapy (RECOVERY), it was reported that dexamethasone reduced COVID-19 deaths by approximately one-fifth and one-third in patients on oxygen therapy and mechanical ventilation, respectively. Dexamethasone was therefore recommended as a life-saving treatment for COVID-19 patients experiencing severe respiratory symptoms."}]