[{"from": "human", "value": "Describe this molecule. [C][C][Branch1][C][C][Branch1][C][C][C][=C][C][=C][Branch1][Branch1][C][=C][Ring1][=Branch1][S][=Branch1][C][=O][=Branch1][C][=O][N][C][=C][Branch2][Ring1][#Branch1][C][=Branch1][S][=N][C][=Branch1][Ring2][=N][Ring1][=Branch1][C][=N][C][=C][C][=N][Ring1][=Branch1][O][C][C][O][O][C][=C][C][=C][C][=C][Ring1][=Branch1][O][C].[O]"}, {"from": "gpt", "value": "The molecule is a sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks the action of endothelin 1, an extremely potent endogenous vasoconstrictor and bronchoconstrictor, by binding to endothelin A and endothelin B receptors in the endothelium and vascular smooth muscle. Bosentan decreases both pulmonary and systemic vascular resistance and is particularly used in the treatment of pulmonary arterial hypertension."}]