Clinical question: History of newly diagnosed MS, restarting Tysabri after pregnancy. Signs and symptoms: As above. Pre-and post-enhanced brain MRI:Examination demonstrates extensive periventricular and to a lesser degree subcortical and corpus callosum foci of flair hyperintensity consistent with patient's known demyelinating disease. There is no convincing evidence of interval change in the extent of the findings. There is no detectable abnormal enhancement to suggest an active plaque.Also stable since prior exam are mild findings of chronic demyelinating disease involving the mid brain, pons and the right cerebellum.The cerebral cortex, cortical sulci and ventricular system remain normal for patient's stated age of 31. Unremarkable images through the orbits, paranasal sinuses and mastoid air cells.
Stable findings of multiple sclerosis and without evidence of new or enhancing lesions since prior exam.