Metastatic melanoma with brain metastases following 4th cycle of immunotherapy. There has been interval decrease in size of the multiple treated supratentorial and infratentorial brain metastases, which contain T1 hyperintense components with susceptibility effect. For example, a left inferior frontal gyrus lesion measures up to 15 mm, previously 19 mm, and a right lateral cerebellar hemisphere lesion measures up to 8 mm, previously 10 mm. There is diffuse nonspecific periventricular white matter T2 hyperintensity. There is no evidence of acute infarct. The ventricles and basal cisterns are unchanged in size and configuration. There is no midline shift or herniation. The major cerebral flow voids are intact. The orbits, skull, paranasal sinuses, and scalp soft tissues are grossly unremarkable.
Interval decrease in size of the treated supratentorial and infratentorial brain metastases.