33 year old with proven left breast cancer presents for I-SPY 2 study #2. There is extreme amount of fibroglandular tissue in both breasts.Moderate parenchymal enhancement is noted in the right breast.The left breast again shows diffuse abnormal enhancement of known cancer, measuring 57 x 86 x 117 mm (AP x LR x CC, previously 65 x 97 x 126 mm). Diffuse edema and skin thickening is slightly decreased. A Hydromark clip is again identified at anterior 12 o'clock position within the tumor in the left breast.A known metastatic left axillary lymph node with Hydromark clip, measures 17 mm in maximum diameter (previously 26 mm). Multiple small cysts are present in the right breast.No abnormal enhancement is seen in right breast. No abnormal axillary lymph nodes are identified in right axillary region.
Known left breast cancer with metastatic left axillary lymph node, slight decrease in size.BIRADS: 6 - Known cancer.RECOMMENDATION: X - No Letter.