### Human:\nit's hard to lose weight with hypothyroid. however if you exercise can you at least be able to tone up?\n\n### Assistant: you can be hypothyroid and still lose weight (and tone up). once you are on thyroid replacement therapy go on a calorie-restricted diet and start a good exercise program. i can guarantee that you will lose weight; perhaps not as fast as you would like but you will steadily lose extra pounds as long as you are on your diet. see a nutritionist if you are having difficulties and always check with your doctor first before starting any diet.