Capital One Cup: previews of Wednesday night's matches Carlisle United v Tottenham Hotspur , kick-off 7.45 Hugo Lloris will get another chance to prove he should by the first choice goalkeeper for Spurs manager Andre Villas-Boas but may learn little from the players in front of him that would be of use in the Premier League. Sweeping changes are expected and Emmanuel Adebayor, Benoît Assou-Ekotto, Younes Kaboul, Jake Livermore, Kyle Naughton and Scott Parker are injured. Carlisle's Paul Thirlwell and Danny Livesey are both expected to recover from head injuries in time to play in front of the club's biggest home crowd of the season. Manchester United v Newcastle United, kick-off 7.45 Darren Fletcher is expected to get his first start for 10 months after being sidelined with illness but the Manchester United side will be filled with some less familiar faces. Chilean striker Ángelo Henríquez could make his debut, while Nick Powell, Alex Büttner and David de Gea may also feature. Newcastle, who have not won at United for 40 years, will use the game to allow Fabricio Coloccini and Cheick Tioté could make their comebacks from injury. Tim Krul and Danny Simpson are still out injured. Norwich City v Doncaster Rovers, kick-off 7.45 Harry Kane, the 19 year-old striker at Norwich on loan from Tottenham, will get the chance to prove he is worth a place in the Premier League as Chris Hughton rotates his squad. Other new signings are also to get a chance to impress including goalkeeper Mark Bunn and midfielders Alexander Tettey and Jacob Butterfield. Winger Elliott Bennett will also be in the squad having recovered from a knee injury, as will youngster Josh Murphy and defender Elliott Ward, who is not on Norwich's Premier League squad list. For Dean Saunders" Doncaster, striker Billy Paynter hopes to have recovered from a calf injury. Queens Park Rangers v Reading , kick-off 7.45 Anton Ferdinand, unlike John Terry at Chelsea, will not play as their FA hearing goes on as he has a hamstring problem but the injury-plagued Kieron Dyer could make only his second start for QPR since joining in July last year. Reading winger Jimmy Kébé, who has been out with a torn hamstring, may feature after playing an hour in a behind-closed-doors match last week and the Premier League's bottom two sides would welcome a fillip for morale. West Bromwich Albion v Liverpool kick-off 8 Striker Shane Long is among those pushing for a return for West Brom against the holders, who should have a point to prove after their dreadful start to the Premier League season. However, their manager, Brendan Rodgers, is expected to follow the trend of fielding a shadow team with goalkeeper Brad Jones coming in for Pepe Reina one of the changes.