Greater Manchester police deaths: Second officer dies after "guns and grenade" murder inquiry arrest TWO unarmed female police officers were killed while attending a "routine incident" today which led to the arrest of one of the country's most wanted men. Two unarmed female police officer die after succumbing to injuries reportedly sustained during arrest of Dale Cregan Cregan was wanted in connection to a separate gun and grenade attack resulting in death of a father and son Cregan arrested on suspicion of the initial murder investigation as well as the suspected murder of a police officer Dale Cregan gave himself up to police soon after the incident, in Hattersley, Greater Manchester Police said. Cregan, 29, was being hunted in connection with separate gun and grenade attacks that killed a father and son. One of the officers died at the scene. The second was critically injured and died afterwards. Assistant Chief Constable Garry Shewan, said: "A long and dark shadow has been cast across Greater Manchester and my thoughts are with the officers" family, friends and colleagues. We will be doing everything we can to support them over the coming days and weeks. Cregan had been the subject of a huge manhunt after the murders of David Short, 46, and his son Mark, 23. A £50,000 reward had been offered for information leading to the arrest of one-eyed Cregan. David Short was killed at his home in Folkestone Road East, Clayton, Manchester, on August 10, while Mark was gunned down at the Cotton Tree pub in nearby Droylsden, on May 25. A gunman walked into the pub and fired shots which injured three other men. A post-mortem examination showed Mark Short died from a gunshot wound to the neck. Police said the two officers had been attending an incident at Abbey Gardens in Hattersley, Tameside, shortly before 11am today. The force did not give any details of the incident but described it as "routine." Police said there were reports that shots were fired and the two officers suffered serious injuries. In a statement, the force added: "A short time later, 29-year-old Dale Cregan was arrested after he walked into a police station in Tameside. Cregan has been arrested on suspicion of two counts of murder in relation to the investigations into the murders of David Short and Mark Short. He has also been arrested on suspicion of the murder of a police officer. Assistant Chief Constable Garry Shewan said: "This is a heartbreaking time for the officers" families and colleagues and our thoughts are with them. This is a tragic day for the whole force and we are currently piecing together exactly what happened this morning. He added: "I understand that the community will be fearful as they hear news of what has happened this morning. We have armed officers patrolling the area and we will aim to keep people updated as much as we can. ACC Shewan announced the first death at a hastily arranged press conference at force headquarters. About an hour later, he issued another statement announcing that the second officer had also died. Home Secretary Theresa May said: "This is a deeply shocking incident and a terrible reminder of the risks that police officers face every day to keep our communities safe." Shadow home secretary Yvette Cooper said: "This is a painful demonstration of how police officers put themselves in harm's way every day to protect the public." President of the Association of Chief Police Officers, Sir Hugh Orde, said: "Whenever police officers and staff lose a colleague that loss is felt right across the police family. The thoughts of everyone in policing are with colleagues in Greater Manchester Police, family and friends of the two officers at this time. Ash Rathband, whose police officer father David was shot and blinded by gun maniac Raoul Moat, called for police to be armed after today's murders. Pc Rathband was found hanging at his home in Blyth, Northumberland, in February, having been blasted in July 2010 while on duty, sitting unarmed in a traffic patrol car. His son tweeted: "It's time for police to be armed in my opinion." His view was echoed by Pc Rathband's twin Darren, who said: "Give them more than a bloody piece of plastic and some spray. Tragic! Four men have already been charged in connection with Mark Short's murder and are due to enter pleas at Manchester Crown Court in November. Earlier this month a 33-year-old man also appeared at Manchester Crown Court charged with the gun and grenade murder of David Short.