Christina Applegate Exits NBC's 'Up All Night' Christina Applegate says she's bowing out of NBC's "Up All Night." In a statement Friday, the actress says the show has taken a "different creative direction" and she's decided to move on to other projects. She called the sitcom a great experience and says she'll miss her co-workers. "Up All Night" starred Applegate and Will Arnett as a couple with a new baby. The show has struggled in the ratings and has seen several changes in its producer ranks. It also was set to change formats, shifting from a single-camera to multi-camera approach when it returned for the rest of its second season. NBC declined to comment on the future of "Up All Night," which last aired in December. The sitcom isn't currently in production.