Unease at Clinton Foundation Over Finances and Ambitions Hillary Rodham Clinton speaking at an American Bar Association meeting in San Francisco on Monday. Soon after the 10th anniversary of the foundation bearing his name, Bill Clinton met with a small group of aides and two lawyers from Simpson Thacher & Bartlett. Two weeks of interviews with Clinton Foundation executives and former employees had led the lawyers to some unsettling conclusions. The review echoed criticism of Mr. Clinton's early years in the White House: For all of its successes, the Clinton Foundation had become a sprawling concern, supervised by a rotating board of old Clinton hands, vulnerable to distraction and threatened by conflicts of interest. It ran multimillion-dollar deficits for several years, despite vast amounts of money flowing in. And concern was rising inside and outside the organization about Douglas J. Band, a onetime personal assistant to Mr. Clinton who had started a lucrative corporate consulting firm - which Mr. Clinton joined as a paid adviser - while overseeing the Clinton Global Initiative, the foundation's glitzy annual gathering of chief executives, heads of state, and celebrities. The review set off more than a year of internal debate, and spurred an evolution in the organization that included Mr. Clinton's daughter, Chelsea, taking on a dominant new role as the family grappled with the question of whether the foundation - and its globe-spanning efforts to combat AIDS, obesity and poverty - would survive its founder. Now those efforts are taking on new urgency. In the coming weeks, the foundation, long Mr. Clinton's domain since its formation in 2001, will become the nerve center of Hillary Rodham Clinton's increasingly busy public life. This fall, Mrs. Clinton and her staff will move into offices at the foundation's new headquarters in Midtown Manhattan, occupying two floors of the Time-Life Building. Amid speculation about her 2016 plans, Mrs. Clinton is adding major new initiatives on women, children and jobs to what has been renamed the Bill, Hillary & Chelsea Clinton Foundation. Worried that the foundation's operating revenues depend too heavily on Mr. Clinton's nonstop fund-raising, the three Clintons are embarking on a drive to raise an endowment of as much as $250 million, with events already scheduled in the Hamptons and London. And after years of relying on Bruce R. Lindsey, the former White House counsel whose friendship with Mr. Clinton stretches back decades, to run the organization while living part-time in Arkansas, the family has hired a New York-based chief executive with a background in management consulting. "We're trying to institutionalize the foundation so that it will be here long after the lives of any of us," Mr. Lindsey said. That's our challenge and that is what we are trying to address. But the changing of the guard has aggravated long-simmering tensions within the former first family's inner circle as the foundation tries to juggle the political and philanthropic ambitions of a former president, a potential future president, and their increasingly visible daughter. And efforts to insulate the foundation from potential conflicts have highlighted just how difficult it can be to disentangle the Clintons" charity work from Mr. Clinton's moneymaking ventures and Mrs. Clinton's political future, according to interviews with more than two dozen former and current foundation employees, donors and advisers to the family. Nearly all of them declined to speak for attribution, citing their unwillingness to alienate the Clinton family. Powered by Celebrity Last Thursday, Mr. Clinton arrived two hours late to an exuberant welcome at a health clinic about 60 miles north of Johannesburg. Children in zebra-striped loincloths sang as Mr. Clinton and Ms. Clinton made their entrance, and the former president enthusiastically explained how his foundation had helped the South African government negotiate large reductions in the price of drugs that halt the progress of HIV. Aaron Motsoaledi, South Africa's minister of health, heaped praise on the effort. "Because of your help we are able to treat three and a half times more people than we used to," he told the crowd. The project is typical of the model pioneered by the Clinton Foundation, built around dozens of partnerships with private companies, governments, or other nonprofit groups. Instead of handing out grants, the foundation recruits donors and advises them on how best to deploy their money or resources, from helping Procter & Gamble donate advanced water-purification packets to developing countries to working with credit card companies to expand the volume of low-cost loans offered to poor inner city residents. Lydia Polgreen contributed reporting, and Kitty Bennett contributed research.