Powerball lottery jackpot jumps to record $425 million for Wednesday's drawing People lined up for Powerball tickets Saturday, the fourth largest Powerball in history. NBC's Thanh Troung reports. DES MOINES, Iowa -- No one won a $325 million Powerball lottery prize on Saturday night, so the jackpot will jump to a record $425 million for the next drawing -- and possibly higher. The winning numbers were 22-32-37-44-50 with Powerball 34, according to the Powerball lottery's website. There were 10 winners of $1 million and one winner of $2 million. Iowa Lottery spokeswoman Mary Neubauer said the jackpot for Wednesday's drawing could go even higher than the estimated $425 million because sales pick up in the days before record drawings. "We'll watch sales to see if an adjustment upwards needs to be made," she said. The cash payout would be be a record $278.3 million. Saturday's estimated $325 million jackpot was the fourth-largest in the game's history. The previous highest Powerball prize was $365 million, won in 2006 by eight ConAgra Foods workers on a single ticket in Lincoln, Neb. Powerball has not had a jackpot winner for two months. The Powerball lottery is held in 42 states, the District of Columbia and the U.S. Virgin Islands. In March, three winning tickets shared the largest U.S. lottery jackpot, the $656 million Mega Millions drawing. The prospect of a big payoff had pulled in Black Friday shoppers in many cities. Gadlin said that if he won, he would return to his grandfather's farm in Heidelberg, Miss., where he spent part of his childhood.