Harlequins bid to emulate last season's Amlin Challenge Cup heroics at Toulon's Stade Felix Mayol Harlequins" prospects took a hit yesterday, though, with news that they will be without two key men, England captain, flanker Chris Robshaw, and New Zealand fly-half Nick Evans, both of whom have short-term injuries. As well as a morale-boosting English victory in Europe, Lancaster would hope to see the likes of Quins centre George Lowe continue his push towards full international honours on the summer tour to South Africa. As they showed at Wembley, however, Harlequins are not daunted by testing challenges. From their 20-12 victory over Munster at Thomond Park, only the second defeat ever suffered by the Irish province in Limerick in a European tie, to winning earlier this season in Toulouse in the Heineken Cup, Quins can now draw on notable experiences. Even though they narrowly failed to go through to the Heineken Cup quarter-finals, and so are one of three teams coming down into the Amlin, there is no sense of the tournament being viewed as a lesser challenge. Quins held on to win 24-19 despite being reduced to 13 men in the closing stages. Lowe was instrumental in that rearguard action as the Premiership leaders held on to extend their lead at the top of the table to six points. Lowe made three try-saving tackles in the match, the last of which on Saracens" Chris Wyles will surely feature in any highlights package of the season. "George had no right to be able to make that tackle, tripping over someone as he closed in but he did," said O'Shea. Lowe would probably have already featured in Lancaster's Saxons Elite Player Squad were it not for an ankle ligament injury in November that sidelined him for 14 weeks. Lowe, who has played for England under 20s, is low-slung and very fast. His presence from the bench against Toulon will be a key factor. Can George play at the highest level? Yes, he can," said O'Shea. More games like last weekend and he has to be in the frame for South Africa. Despite starting favourites, Toulon are well aware of the threat posed by Harlequins. "Quins have shown that they are capable of beating anyone and should be considered the equal of a Toulouse or Clermont," said Wilkinson."They have a unique spirit." If there were any added incentive needed, Harlequins will play the semi-final as well as final at their home ground, the Twickenham Stoop, were they to win.