Giants Reliever Mota Gets 100-Game Drug Suspension San Francisco Giants reliever Guillermo Mota was suspended for 100 games on Monday, becoming just the third major league player penalized twice for positive drug tests. The commissioner's office said the 38-year-old right-hander tested positive for Clenbuterol. In November 2006, while with the New York Mets, Mota was suspended for the first 50 games of the next season. "The Giants are disappointed to learn of Guillermo Mota's suspension," the team said in a statement. The Major League Baseball Players Association filed a grievance challenging the suspension that will be heard by an arbitrator. Under baseball's drug agreement, grievances for initial positive tests are heard before a suspension is announced but cases involving second or third positives are argued after the penalty is made public. Outfielder Manny Ramirez and catcher Eliezer Alfonzo are the only previous players to twice test positive. No player has tested positive a third time, which would result in a lifetime ban. Mota was 0-1 with a 5.06 ERA in nine games for the Giants this year. This is his 14th season in the majors. Mota has been a setup man and middle reliever throughout his career. He is 39-45 with 10 saves in 726 games while playing with Montreal, the Los Angeles Dodgers, Florida, Cleveland, the New York Mets, Milwaukee and San Francisco. This is Mota's third season with the Giants. He was with the Mets when he previously suspended and missed the first 50 games of the 2007 season. At the time of that suspension, the identity of the substance causing the positive test was not announced. Ramirez served a 50-game suspension while with the Los Angeles Dodgers in 2009, then retired rather than serve a 100-game ban while with Tampa Bay last year. Because Ramirez sat out nearly all of 2011, his penalty was cut to this first 50 games of this season under an agreement between management and the union that allowed him to end his retirement. He agreed to a minor league contract with Oakland. Alfonzo was suspended for 50 games in 2008 while with San Francisco and for 100 games last September while with Colorado.