Can there be any doubt that we are becoming desensitized to gun violence? Look the first item in today's report. A Chicago teenager who had moved to California - to escape gun violence! - was shot to death when he came home for summer break. The Chicago Tribune ran a story on the killing, but it merited just a few paragraphs at the top of a roundup of overnight shootings. It was awarded three paragraphs at a local news site. In our marathon Memorial Day wrap-up, we included news of a Marine stationed at Camp Lejeune who stabbed his wife before embarking on a shooting spree that killed one person and injured five, including a sheriff. The gunman was later killed by police, who discovered an assault-style rifle, a handgun and hundreds of rounds of ammunition. Today we bring you news of a man who shot and killed a man and injured two others in a shooting spree in Houston, barricaded himself in an apartment and was eventually drawn out by SWAT negotiators. Up until a few years ago you'd expect to see a shooting like that on the front page. A 15-year-old boy was shot and killed on Chicago's South Side Thursday. Patrick Sykes, who had moved to California six months ago to escape the violence and returned home last week for his summer break, was shot three times. Sykes's father was reportedly killed two years ago about two blocks from Thursday's shooting and his murder remains unsolved. Seven others were shot between Thursday afternoon and Friday morning across the city. A man fatally shot another man and wounded two others before barricading himself in a northwest Houston, Tex., apartment Thursday. Joshua Mayfield, 33, shot and killed 70-year-old Donald Waguespack, who was helping him fix his car. Mayfield then opened fire on a motorcycle rider, critically injuring him; the bullet ricocheted and struck another person in the shoulder. It took a negotiator a couple of hours to get Mayfield to surrender, but he came out at 3 a.m. and confessed. Two people were killed and a third was injured in a shooting in southeast Missouri Thursday morning. Matthew Joseph, 18, and Mary Joseph, 57, were found dead of gunshot wounds just before 8 a.m. at a brick home in an affluent area of Cape Girardeau. George Joseph, 48, was found alive with gunshot wounds and taken to a hospital. Police declined to discuss the relationship of the three but said they are not looking for suspects. Two double shootings in Philadelphia, Pa., Thursday night killed one person and injured three. A 35-year-old man was shot in the back multiple times and killed and a 22-year-old man was hospitalized in South Philadelphia at around 10:40 p.m. Police found both men lying on the sidewalk and said at least nine shots were fired. Nearby security cameras may have captured part of the shooting. Earlier, two men were shot in North Philadelphia's Hartranft section. Both are in stable condition. Philadelphia police arrested a juvenile in the Kensington area who may have accidentally shot his cousin while playing with a gun. Officers found an 18-year-old man inside a home with a gunshot wound to the stomach shortly before 6:30 p.m. He is expected to survive. 6abc.com Two teenagers were injured in a drive-by shooting in downtown Fresno, Calif., Thursday. Witnesses said a van pulled up to one of the victim's homes and began shooting. The boys, 15 and 16, dropped the bicycles they were riding and ran for cover, but were struck by the spray of bullets. Family members found them bleeding in the backyard. Police believe the attack is gang related. A 19-year-old man was killed in a shooting in Lakewood, Calif., Wednesday afternoon. The victim was shot at close range in the front yard of a home by two suspects who fled in a sedan. A neighbor said the two brothers who live in the house have had run-ins with authorities in the past. "This scares the tar out of me," said a woman who has lived on the street since 1975. This has never happened here. Press-Telegram Felipe Banderas, 19, was shot and killed on a street corner in San Jose, Calif., early Thursday. Banderas moved to the East San Jose neighborhood last month and his family said gang members had recently started approaching him. "There are two gangs out here and one gang is trying to pull him and another is trying to pull him and he was holding his mug and saying, "I'm not going to join no gang,"" said Robert Rios, a former gang member. And somebody got him. A shooting left a woman dead and two men wounded in Newark, N.J., Wednesday night. Laqueebah Murray, 29, was shot at around 11:35 p.m. and died at the hospital. Police evacuated a building where they believed the gunman might be hiding and blocked off several streets. CBS New York Two men were shot, one critically, in a shooting in the Foxhurst section of the Bronx, N.Y., Thursday. A man in his 20s suffered a life-threatening gunshot wound to the face and another man was shot in the hip at around 6:20 p.m. A responding ambulance collided with another vehicle, critically injuring the car's driver. The NYPD is investigating the shooting and the accident. New York Post A man in his 30s was hit by gunfire and killed in the East Hill neighborhood of Kent, Wash., Thursday morning. Police say they only have a vague description of a suspect and are investigating what led up to the shooting. A man was shot and killed at a car wash in the Whitehaven area of Memphis, Tenn., Thursday afternoon. Deangelo Watkins, a forklift driver in his late 20s, was shot three times, and a witness saw two men leave the scene. It's out of control. Memphis needs help," a witness said. WREG Memphis A shooting in the affluent Oak Park section of Chicago Thursday evening has residents puzzled. Police are releasing few details but confirmed someone was shot, and neighbors saw someone being taken away in an ambulance. Shootings are nearly unheard of in the neighborhood, a resident said. Police are investigating a shooting in west Modesto, Calif., Thursday afternoon that left a man in critical condition. Witnesses at the scene said they heard about 10 shots fired from what sounded like the same gun and saw two men running from the area. Emergency crews performed CPR on the victim, who is now at the hospital. Police are trying to identify a man found shot to death shortly after 1 a.m. in the College Hill neighborhood of St. Louis, Mo. The victim, who had no identification on him, was found on the ground next to the driver's side of a vehicle. Police have no suspects. The area has seen several fatal shootings in recent months. According to Slate's gun-death tracker, an estimated 4,537 people have died as a result of gun violence in America since the Newtown massacre on December 14, 2012.