Tractor trailer, cargo train collide outside Baltimore Updated 5:44 p.m. A tractor trailer and a CSX cargo train collided Tuesday afternoon, derailing about 15 train cars, rocking the Baltimore region with a huge explosion and sending a plume of smoke into the air that could be seen for miles, CBS News affiliate WJZ reports. CSX spokesman Gary Sease said the train was en route from Silkirk, N.Y., to Waycross, Ga., when it collided just after 2 p.m. in Rosedale, just northeast of Baltimore City. Shocked residents said the ground shook and windows were blown, leading many to think and earthquake occurred or bomb had gone off. A picture of the train derailment submitted via Twitter by Brianna Bailey in Rosedale. / CBS Baltimore/Twitter WJZ's Adam May reports the tractor trailer driver is in the hospital in serious but stable condition. No other injuries have been reported. Residents in the Pulaski/Moravia area are asked to stay indoors and police are telling people to evacuate from the 20 blocks around the incident. Sease said at least one of the rail cars that derailed held sodium chlorate, an oxidizer that is classified by the U.S. Department of Transportation as a hazardous material, but city officials clarified there were not toxic materials in the air. Baltimore County Police tweeted that several nearby buildings collapsed and Hazmat teams are responded to the scene. According to Baltimore County Executive Kevin Kamenetz, two cars caught on fire: One contained terephthalic acid, which is used in making plastic, and another held fluoroacetic acid. A WJZ viewer told the station he was about a quarter of a mile away at his friend's house when the explosion happened. We went outside of his house, which is right on the top of Route 40 at Philadelphia Road. We were watching the fire, and then all of a sudden the explosion happened and actually knocked me off my feet. The window broke out in his house. You could feel the heat on our faces. I never seen anything like it," he said. A customer at a nearby print shop said windows blew out and ceiling fixtures fell, and at least 100 people were evacuated from the store. Some thought that a bomb had gone off. And a neighbor who lives just around the corner from the epicenter of the blast said she was working when she heard the loud explosion. Boom! And that rocked the house," she told WJZ. The whole house shook. The glass doors all shook. I shook," she said. It was a jolt like the earthquake we felt. We kind thought it was something like that. Route 40 in the area is closed in the area in both directions.