To some, the Wythe Hotel in Williamsburg may represent the way Brooklyn is changing, but it's sticking with the borough's tradition of keeping it in the family. Opening next Tuesday is a new boutique known as the Shop, with a theme and offerings chosen by one local mastermind, which will change every four to six months. The first curator is the fashion designer Caron Callahan, whose label is based in the neighborhood. Her husband, Sean Rembold, is the executive chef at the restaurant Marlow & Sons, owned by Andrew Tarlow, who is also the man behind the Wythe. "They were looking for something that gave a little energy to that nook," Callahan said. There's so much happening here, and the taste level is super-high. So Callahan filled the shop with a slew of goods from friends and friends of friends. This includes wares from indie labels like Ulla Johnson, Shuron ("My husband is a big fan of their sunglasses") and Building Block, as well as cool-kid collections Assembly New York, Jeremy Laing and Marlow Goods (the brainchild of Tarlow's wife, Kate), along with home goods, jewelry, children's clothing, books from the local publisher Melville House Books and Ugly Duckling Presse, and an apothecary curated by the natural beauty expert Jessa Blades. If there's anything linking the various selections, Callahan said, it's that "my style tends to be tomboyish, and I tried to bring in a lot of unisex things." Not everything is local or Brooklyn made, but she says that every chosen product evokes the artisanal sensibility for which Brooklyn has become notorious. "The fact that the Wythe is quasi-family run, and it's not this huge corporation, it makes it more Brooklyn-feeling," she said. Caron Callahan at Wythe Hotel opens Sept. 3; 80 Wythe Avenue., Brooklyn; wythehotel.com.