50 Shades of Grey: who else could play Grey and Ana? EL James' novel shot up the bestseller list because of its dark S&M antics in the bedroom. Christian Grey is a predatory figure, who, some may say, preys on the naive and inexperienced Anastasia Steele. The scene is set for a grisly Blue Beard-esque relationship, and who better to star in a film about manipulation than Silence of the Lambs actors Anthony Hopkins and Jodie Foster? Fifty Shades of Grey: The rom-com Starring: Vince Vaughn and Jennifer Aniston Although the book is about a turbulent romance, it's unlikely there will be much levity in the film adaption. But perhaps there should be. In the capable hands of seasoned romantic comedy actors Vince Vaughn (at 6'5" he's got enough height to be Grey) and Jennifer Anniston (she's a little older than 22, but it could work), Fifty Shades of Grey could be a life-affirming 90 minutes of whimsy and amusing sexual mishaps. Fifty Shades of Grey: The silent movie Starring: Greta Garbo and Conrad Nagel A little less conversation, a little more action please. Perhaps Fifty Shades of Grey could take a note out of The Kiss's book, the 1929 film and final silent movie for Greta Garbo. A lack of lines didn't stop illicit romances, heavy-petting and murder from creeping into the film's storyline, and given James's unique knack for dialogue, the forthcoming film may even benefit. Fifty Shades of Grey: The action film Starring: Vin Diesel and Jordana Brewster Brewster and Diesel have starred alongside each other as Mia and Dominic Torretto in the Fast and Furious franchise, and with her dark hair and fine features, Brewster could make a good Ana. Grey and Ana's dramatic romance should be able to accomodate some daring stunts, and the genre twist may improve box office figures. Fifty Shades of Grey: The period drama Starring: Colin Firth and Jennifer Ehle Who wouldn't want to see the ultimate period drama heartthrob as Christian Grey? Jane Austen's Mr Darcy was one of the first Byronic heroes, paving the way for the dark and brooding romantic men like Grey. Add to the mix the potential for seeing wet, frilly shirt scenes and more, and Colin Firth may just nail it.