Red Sox say Jon Lester will start Game 1 of World Series Red Sox left-hander Jon Lester will start Game 1 of the World Series against the St. Louis Cardinals. That's the word on Monday from Boston manager John Farrell. Farrell says he hasn't decided on his entire lineup, but designated hitter David Ortiz will start at least once at first base when the series shifts to St. Louis for the middle three games. There is no DH allowed in the NL park, meaning Ortiz will have to play the field for just the seventh time this season. The Red Sox worked out Monday, two days after eliminating the Detroit Tigers in Game 6 of the AL championship series. Game 1 of the World Series is Wednesday night at Fenway Park.