Madeleine McCann: E-fits of 'suspect' released Detectives from Scotland Yard, who have been leading a fresh investigation into Madeleine's abduction, will use tonight's programme to also reveal significant new thinking around the timeline of the events leading up to her disappearance. A detailed reconstruction of the McCann family's movements on the afternoon and evening of May 3, 2007, will be broadcast in the hope of jogging someone's memory and unlocking a crucial clue. More than 440 witnesses have been spoken to by officers, who have spent two years reviewing all the evidence collected by Portuguese police and private detectives. As well as identifying 41 "persons of interest," the Scotland Yard inquiry - dubbed Operation Grange - has thrown up a number of potential suspects who witnesses have been able to describe in detail. A spokesman for the Operation Grange team said detectives now had a far more detailed understanding of the times when an abduction could have taken place and this had given the statements from two witnesses particular significance. Detective Chief Inspector Andy Redwood, the senior investigating officer, said: "Today I am asking the public for their help. Whilst this man may or may not be the key to unlocking this investigation, tracing and speaking to him is of vital importance to us. We have witnesses placing him in the resort area around the time of Madeleine's disappearance. This is far from our only line of inquiry and there will be e-fits released of other sightings as well, who we are equally keen to trace. These people were seen on the day of Madeleine's disappearance and the days leading up to it. The Portuguese authorities shelved their investigation into Madeleine's disappearance in July 2008, forcing her parents, Kate and Gerry McCann, to employ teams of private detectives to continue the hunt. But in May 2011, four years after her disappearance, the Home Secretary, Theresa May, with the backing of Prime Minster David Cameron, ordered Scotland Yard to begin a review of all the evidence. Earlier this summer the Metropolitan Police announced the review was being turned into a formal investigation with more than 30 detectives and police staff working on the case full time. After months of careful negotiations, their counterparts in Portugal, the Policia Judiciaria, agreed to co-operate and there are now six dedicated officers based in Faro on the Algarve. The e-fit images are seen as a significant step forward in the investigation, but it is hoped the Crimewatch reconstruction will also throw up some fresh lines of inquiry, despite the passage of time. The appeals will also be broadcast in Germany and Holland where many of the tourists staying in Praia da Luz at the time were from. DCI Redwood explained: "Where we have been able to make massive steps forward is by drawing together all the material gathered to date, and reviewing it as a whole. We continue to put Madeleine at the heart of our investigation and I would urge people to watch Crimewatch tonight and if you can help identify this man or have any information about our new appeal points please contact us. He added: "If you were in and around the Praia da Luz resort on Thursday, 3 May 2007, but you have not yet spoken to police, and you think you may have information, please pass it on. I would also like to ask for the help of the local community in Praia da Luz. Portugal is a key country for us to trace any outstanding witnesses and our appeals will be repeated there. We still have a lot of material to investigate and much work to do. Your information could be the vital piece we need to finally answer what happened to Madeleine. Tonight's broadcast will also feature an emotional appeal from Mr and Mrs McCann, who describe their continuing torment. Mr McCann will say: "When it's a special occasion, when you should be at your happiest and Madeleine's not there, that's when it really hits home. His wife adds: "It's when you have big family occasions really. She adds: "We're not the ones that has done something wrong here. It's the person who's gone into that apartment and taken a little girl away from her family.