Madeleine McCann: Seven suspects to be questioned over the disappearance of the missing three-year-old The last photo taken of missing British girl Madeleine McCann. SEVEN people will be questioned as suspects in the disappearance of Madeleine McCann this month. The interviews, to take place between November 24 and 28, could provide major breakthrough in the investigation that has become one of the greatest mysteries in criminal history since the three-year-old went missing while on holiday in Portugal in 2007. Madeleine's disappearance has been one of the most publicised in recent years. Portuguese police will question five men and two women who are believed to have been at the resort where the McCanns were holiday on May 3, 2007, ITV reports. British police have requested to sit in on interviews. It has been reported that some of those being questioned have spoken to police before and have criminal histories, though none of them were known to the family. The breakthrough follows extensive reviews of mobile phone activity on the night, and it has been reported the group were in contact with each other by text message on the night of Madeleine's disappearance. Four more people are believed to be quizzed by police as witnesses. Apartment hotel building at holiday resort in Paia da Luz in Portugal where Madeleine went missing. The seven suspects are all said to be familiar with Praia da Luz - the holiday resort where Madeleine was last seen - and some are said to be former employees of the Ocean Club holiday complex where the family was staying. The unsolved disappearance of Madeleine has given rise to numerous conspiracy theories throughout the more than eight year investigation. The finger was initially pointed at Madeleine's parents, Gerry and Kate McCann, who have since been cleared. Kate and Gerry McCann appeal for information in 2013 with an image of what she may have looked like at age nine. The three-year-old was laid down to sleep while her parents went to dinner at around 8.30pm on the night of her disappearance. After a number of checks on Madeleine and her young twin brother and sister, she was discovered missing and the police were called. Since then, a number of suspects have been investigated and cleared of any involvement, including a convicted burglar with a drug habit, a former employee of the resort who was believed to be in the hotel that night. Madeleine's parents have never given up hope in finding their daughter and have ensured her mysterious disappearance remains one of the most publicised in recent times. Originally published as New suspects in Madeleine's disappearance