ISAF: U.S. service member detained for shooting Afghans From Sara Sidner, CNN March 11, 2012 -- Updated 0711 GMT (1511 HKT) The shooting takes place off base, ISAF says It results in "multiple" casualties, according to an official Civilian casualties as a result of NATO action have long caused anger in Afghanistan Kabul, Afghanistan (CNN) -- A U.S. service member was detained Sunday after he shot Afghan civilians in Kandahar province, the NATO-led coalition said. Capt. Justin Brockhoff with the International Security Assistance Force (ISAF) said the incident took place off base and wounded "multiple" civilians. The injured Afghans were being treated in ISAF facilities. Brockhoff said officials do not yet have a motive for the shooting, which is under investigation by both NATO and Afghan officials. "This is a deeply regrettable incident and we extend our thoughts and concerns to the families involved," a statement from ISAF said. Kandahar has been one of the areas wracked by violence since news emerged late last month that U.S. troops mistakenly burned Qurans and other religious materials. Furor over the burning left dozens dead, including four American soldiers. Hundreds more were wounded. Civilian casualties as a result of action by the NATO-led international coalition have long caused anger in Afghanistan, adding pressure on international forces to withdraw. The international force has said avoiding civilian casualties is a high priority. "My command's mission is to protect the civilian people of Afghanistan," Gen. John R. Allen, ISAF commander, said last month. I take very seriously the loss of every Afghan life. We will continue to do all we can to ensure the safety of the Afghan population. The number of ISAF-caused civilian deaths decreased by nearly 17% from 2010 to 2011, the coalition force said in its December monthly report. CNN's Claudia Dominguez contributed to this report.