pattern_name: hypertrophicAnatomicalEntity

pattern_iri: http://purl.obolibrary.org/obo/upheno/patterns-dev/hypertrophicAnatomicalEntity.yaml

description: 'Use this pattern for overgrowth of multicellular structures due to overgrowth and enlargement of their cells. When the mechanism is unknown or for enlargement of any other type of structure, including enlargement of single cells, please use abnormallyIncreasedSizeOfAnatomicalEntity.'

#  examples:
#    - http://purl.obolibrary.org/obo/HP_0003712  # Skeletal muscle hypertrophy
#    - http://purl.obolibrary.org/obo/MP_0009461  # skeletal muscle hypertrophy
#    - http://purl.obolibrary.org/obo/MP_0000053  # excessive ear growth
#    - http://purl.obolibrary.org/obo/MP_0005603  # neuron hypertrophy
#    - http://purl.obolibrary.org/obo/ZP_0016896  # kidney hypertrophic, abnormal
#    - http://purl.obolibrary.org/obo/ZP_0007444  # ciliary zone hypertrophic, abnormal

contributors:
  - https://orcid.org/0000-0001-8314-2140  # Ray Stefancsik
  - https://orcid.org/0000-0001-5208-3432  # Nicole Vasilevsky
  - https://orcid.org/0000-0002-9900-7880  # Yvonne M. Bradford
  - https://orcid.org/0000-0002-7073-9172  # David Osumi-Sutherland
  - https://orcid.org/0000-0003-4606-0597  # Susan Bello

classes:
  hypertrophic: PATO:0000584
  abnormal: PATO:0000460
  multicellular_anatomical_structure: UBERON:0010000

relations:
  characteristic_of: RO:0000052
  has_modifier: RO:0002573
  has_part: BFO:0000051

annotationProperties:
  exact_synonym: oio:hasExactSynonym

vars:
  anatomical_entity: "'multicellular_anatomical_structure'"

name:
  text: "hypertrophic %s"
  vars:
    - anatomical_entity

annotations:
  - annotationProperty: exact_synonym
    text: "%s hypertrophy"
    vars:
      - anatomical_entity

def:
  text: "Increased size of %s due to overgrowth and enlargement of its constituent cells."
  vars:
    - anatomical_entity

equivalentTo:
  text: "'has_part' some (
        'hypertrophic' and
        'characteristic_of' some %s and
        'has_modifier' some 'abnormal')"

  vars:
    - anatomical_entity
