In this collection of essays and an interview, effectively translated by Bruno Bosteels, the renowned French philosopher, novelist, and playwright Alain Badiou stresses that theatre is "the figurative reknotting of politics" (13). Theatre and politics both occur at public gatherings "with the intent of a spectacle"; actors and politicians are "physically present" in locations reserved for the "express purpose of the gathered public's consideration"; and in politics and theatre, a "referent" exists through which "the spectacle can be said to be the representation" (6). Badiou justifies theatre's cohabitation with the political when he asks: "What does theatre talk about if not the state of the State, the state of society, the state of revolution, the state of consciousness relative to the State, to society, to the revolution, to politics?" (36). This last remark situates Badiou within the French philosophical-leftist traditions of Althusser, where theatre works for or against the "state ideological apparatus"; Foucault, where theatre resists or defends state "biopower" that subjugates bodies; and Derrida, where the performance of différance challenges the status quo through ephemerality, alterity, and saturation of presence and nonpresence.


The degree of sensitivity of asthmatics is best determined by skin-testing with dilutions of extracts of increasing strength, and apparently not by the reagin content of the blood; this point requires further study. Asthma patients sensitive to rabbit hair, horse dander, or cottonseed, can be classified, by the intradermal or scratch method, into three arbitrary groups, A, B, and C, depending upon the degree of skin sensitivity. The number of constitutional reactions, resulting from intradermal diagnostic tests or specific treatment, will be appreciably reduced if the degree of sensitivity is predetermined.


ABSTRACT Existing work suggests that status hierarchies in the world polity are primarily realized through uneven participation rates in international organizations. Meanwhile, hierarchies that exist within these organizations remain neglected. I fill this gap by examining the unequal distribution of voting power at the International Monetary Fund (IMF) and the World Bank between 1951 and 2010. I first show that, while gross domestic product levels are converging between countries, votes at the IMF and World Bank are not. I then examine country-level factors associated with quota votes at the IMF and share votes at the World Bank. Net of the variables that comprise the official voting formulas, social networks tend to play a prominent role in how votes are allocated. Overall, these findings highlight the importance of examining power, material interests, and discretion within world polity institutions.


Product development at the Stanley Works is now much more centralized than it was previously. Engineers are focusing on fundamental design problems, and their goal is to totally reinvent the basic tools rather than just make incremental improvements on existing designs. Not surprisingly, ergonomics is playing a major role in the development of new hand tools.


The establishment and dispersal of introduced species of birds is best documented by the many studies of the House Sparrow (Passer domesticus) (Johnston 1964, 1973; Hudson and Kimzey 1966; Selander and Johnston 1967; Johnston and Selander 1971, 1973; Johnston et al. 1972; Blem 1973, 1974, 1975), and the Eurasian Starling (Sturnus vulgaris) (Kessel 1953, 1957; Blem 198 1). However, with very few exceptions (Lack 1949, Calhoun 1947), most of this research did not occur until many years after the populations were first established. The recent introduction of the House Finch (Carpodacus mexicanus) into the eastern half of the United States (Elliott and Arbib 1953, Aldrich and Weske 1978) and dispersal into Virginia (Blem and Mehner 1981) provided us the opportunity to examine avian adaptation to a new environmental regime as it occurred and not after the fact. The present study: (1) documents the metabolic response of Virginia House Finches to ambient temperature, photoperiod, and food composition; and (2) quantifies the poor tolerance of Virginia House Finches of low temperatures. The dependence of these birds on artificial food sources for survival may be a possible ecological basis for significant morphological differences, particularly increased bill size, which have arisen between the eastern race and the parental stock (Aldrich and Weske 1978, Aldrich 1982). METHODS


Libraries are transforming to satisfy the paradigm shift in information search possibilities impacted by the Internet, through a migration to virtual space. World over, libraries are pressurized by patrons and managements to prove the necessity of their existence. Being in a service oriented sector and having monopoly of holding information, libraries till recently never felt the need for marketing. In reality libraries are indispensible, as reliable information is never available free and in practice it is more difficult to locate in the Internet. To justify the necessity of its existence, libraries should use imaginative, clever and economic marketing strategies to win patrons and also to convince management. VSSC Library supports satellite launch vehicle research and development program of the Indian Space Research Organization. To promote online resources and to get best Return on Investment, a marketing drive was initiated in 2012 using an innovative tool 'Open book written quiz'. The goal was to inspire the library patrons to learn and use library products and services through a quiz program. There was no examination hall or invigilator to monitor the quiz. Patrons were free to carry the answer sheet anywhere they wanted, read the quiz guide with answers, consult - websites, colleagues, or library staff to answer the quiz. The intention was not to measure the knowledge but to impart more knowledge about the library. The innovative approach surprised the patrons as they received the answers well ahead of the quiz. A short survey rated this program as excellent and all 688 participants agreed that they benefited greatly by taking the quiz. This paper illustrates the new library marketing tool 'innovative written quiz' and a program called 'MyLibrary' which were effectively utilized to market VSSC Library to a large user base in just 11 days.


Abstract: The decision of buying and selling shares and also keeping and removing ownership of shares of financial asset is strategic decision for the investors since it is related with the gained return chance. Global crisis gives quite big impact to the Indonesian Stock Exchange and also changes the investor behavior as well. Fundamental exchange which is considered fragile becomes instability threat and reflects uncertain condition. This research aims to analyze and explain empirically the impact of variance return, trading volume, stock prices and return shares toward bid-ask spread which is the measurement of asymmetrical information cost, also the impact of variance return, market value, bid-ask spread and dividend pay out towards common shares holding periods in Indonesia Stock Exchange and some dominant variable that affect them. The findings of this research strengthen the presumption that in conducting the investment, investors in Indonesian Stock Exchange is more oriented to short term investment by expecting more on common shares than dividend. Most investors keep their ownership in common shares in Indonesian Stock Exchange for two years. Besides, the efficient investment strategy which optimizes profit is "switching strategy", following the market movement every time exactly, using technical information to active shares by moving from the shares that the price is predicted to decline to the increased ones. Moreover, the researcher also got the evidence that the investors in Indonesian capital market conduct their investment irrationally, investor's analysis is getting technical and gives less attention to the fundamental factors. The decision of selling and buying which is conducted by the investors on common shares is based on the trading activity, that is actually a measurement of the scale of asymmetry information. Keywords: asymmetrical information, holding periods, ownership of lq 45 shares, variance return, bid-askspread, dividend pay out


Support vector machine is applied to springback forecasting for steel structure in the paper. In the steel structure, pressure-pad-force, friction coefficient and die filleted corner have a certain influence on springback amount.We employ BP neural network to compare with support vector machine to show the superiority of support vector machine in this study. Finally,we give the comparison of the prediction error of springback for steel structure between support vector machine and BP neural network. Evidently,the springback prediction for steel structure of support vector machine is better than that of BP neural network.


In nursing research, one should be interested in phenomenological research (JPN NURS RES, 2011a) as well as caring (JPN NURS RES, 2011b). Due to holding an interest in both these areas and participating in a collaborative project called 'Phenomenology of Caring', I have further interest in 'Nordic Caring' as a contact point between phenomenology and caring. Therefore, for two years, I have been engaged in an interdisciplinary collaborative research titled 'A research into theoretical grounds and philosophical backgrounds of Nordic Caring based on field work'. The collaborators on this study are from fields such as philosophy, ethics, thanatology, nursing science, rehabilitation science, social welfare and cultural anthropology.


Purpose: The aim of this study was to report on the prevalence of Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Mycoplasma genitalium (MG), and Ureaplasma urealyticum (UU) in patients with chronic prostatitis (CP) IIIa and CP IIIb using PCR and correlations between four microorganisms and other clinical parameters. Materials and Methods: The medical charts of 206 Patients who visited National Police Hospital and were diagnosed with CP IIIa and CP IIIb between January 2011 and December 2012 were reviewed. We investigated white blood cell (WBC) counts on expressed prostatic secretion (EPS) samples and the frequency of four possible causative microorganisms of prostatitis, CT, NG, MG, and UU, using PCR techniques on first voided urine samples (VB1). Results: Of 206 patients, 88 patients were CP IIIa and 118 were CP IIIb, with a mean age of 33.8±12.9 and 34.6±11.3, respectively. CT, NG, MG, and UU were detected in 13.6%, 0%, 4.5%, and 14.8% of CP IIIa patients and in 0.8%, 0%, 3.4%, and 11.9% of CP IIIb patients, respectively. Among men aged 19-30, detection of CT was significantly greater in the CP IIIa group than in the CP IIIb group (p=0.002). CT showed a positive association with EPS or the third voided urine (VB3) WBC count grade (p<0.01), however, MG and UU did not. The relationship between numbers of detected microorganisms and WBC counts was statistically insignificant. Conclusions: In subgroup analyses, microorganisms were detected in by PCR in 29 CP IIIa patients (32.9%) and 19 CP IIIb patients (16.1%). Young aged men in the CP IIIa group showed high prevalence of CT, and patients in whom CT was detected in urine PCR had high EPS WBC counts.


This study seeks to develop evaluations that assess user satisfaction with digital exhibitions of archival material. The study also aims to recommend evaluation methodologies appropriate for cultural heritage institutions with few resources. The study evaluates an exhibit created for Durham County Library in Durham, North Carolina, by using an online survey and one-on-one interviews. These two methodologies are compared qualitatively on their abilities to suggest improvements or enhancements for the exhibit, and quantitatively on three factors: number of usability problems revealed, response rate, and implementation cost. On the substantive factors of suggested improvements and usability problems, using both methodologies is most effective. For response rate and implementation cost, however, the online survey was far more effective than one-on-one interviews.


The group of scale insects here to be considered has commonly been characterized as the Lecaniine scales, owing to the fact that the genus Lecanium was for long regarded as its type. With the shifting of the group type to the genus Coccus it has been generally accepted as the subfamily Coccinœ of the family Coccidœ . The group appears, however, to be of family rank, a position that has been suggested by Professor Ferris, and it will therefore be treated in this paper as the family Coccidœ of the superfamily Coccoidea .[1][1]

 [1]: #fn-1


Yttrium gallium garnet (YGG) submicrocrystals having 80 nm average diameters doped with Cr3+ (0.1–40%) were synthesized by the citrate method. Pure cubic garnets were obtained in wide range (0.1–15%) of dopant concentration. Chromium ions replace Ga3+ at the octahedral sites and experience an intermediate or weak crystal field, depending only on Cr3+ concentration. The weak crystal field is observed when the dopant concentration exceeds 3%. The origin of such behavior is discussed.


In Co-operative systems, cars on the road communicate with each other or with central information systems via custom messages and exchange information. This information exchange will alert drivers of the traffic ahead and helps in accident prevention or in optimizing the path to the destination. The indicative list of information shared would be hazardous situations at intersection, accident detection on the path, intimation of construction or repair works blocking roads that can alert drivers to take alternate routes and traffic information construction site and maintenance information, traffic Information among others.


A key component to teaching successful readers is to create a strong foundation of comprehension skills. One research-based method of comprehension instruction is Reciprocal Teaching (RT). RT has been proven effective at boosting comprehension with students in upper grades; however, there is less data available to support this claim at the elementary level. This study explored the impact of a modified RT approach in a first grade classroom, through whole group read-alouds and scaffolded small group interactions, on student comprehension. Students received explicit instruction of the reading strategies: predicting, clarifying, questioning and summarizing, and then opportunities to take ownership for their learning and practice the strategies independently in small groups. Findings indicate that students' comprehension was impacted and student discourse regarding comprehension strategies became more complex.


The intestinal crypt is maintained by a population of stem cells that compete for space within the crypt base niche. Typically identified by Lgr5 (Leucine- rich repeat- containing G- protein- coupled receptor 5) expression, only a portion is capable of repopulating the crypt (effective stem cells). Azkanaz et al used intravital microscopy to permit real- time visualisation of labelled Lgr5+ stem cell dynamics within a live intestine. This technique revealed that while the small intestine (SI) and large intestine (LI) contained approximately the same number of Lgr5+ stem cells, there were two times as many effective stem cells in the SI as the LI. Defining the starting position within the crypt and following them over 8 weeks, stem cells on the niche border were often capable of remaining as effective stem cells in the SI, whereas none of the border Lgr5+ stem cells in the LI were capable of long- term repopulation. Imaging revealed that SI border Lgr5+ stems were able to move in a retrograde fashion down the crypt axis that LI border stem cells could not. SI crypts contain Paneth cells capable of producing Wnt (Wingless/Integrated) and 3D (three- dimensional) organoid tracing of Lgr5+ stem cells exposed to Wnt3a (Wnt family member 3a) demonstrated a clear increase in stem cell movement that could be prevented by a Wnt3a inhibitor. More effective increased the for clonal conversion, indicating a higher rate of stem cell competition within the SI therapy were evaluated in the phase- 3 ADVANCE (n=931) and MOTIVATE (n=618) induction trials in active Crohn's disease patients. The coprimary endpoint rates of clinical remission at week 12 for 600 mg and 1200 mg Risankizumab versus placebo were 45%, 42% versus 25% in the ADVANCE and 42%, 40% versus 20% in the MOTIVATE trial for the Crohn's disease activity index (CDAI) and 43%, 41% versus 22% as well as 40%, 32% versus 12% for stool frequency and the abdominal pain score. The coprimary endoscopic response rates were 40%, 32% versus 12% in the ADVANCE and 29%, 34% versus 11% in the MOTIVATE trial. All coprimary endpoints at week 12 were met in both trials with both doses of Risankizumab (p≤0·0001). Patients with clin ical response to Risankizumab in the induction studies entered the phase 3 maintenance trial FORTIFY (n=712) and were assigned to either the Risankizumab 180 mg, 360 mg or the placebo group. Greater clinical remission rates of 52% versus 41% (CDAI) and 52% versus 40% (stool frequency and abdominal pain score) as well as endoscopic response rates of 47% versus 22% were reached for Risankizumab 360 mg versus placebo. Risankizumab treatment was well tolerated. This is the first study in Crohn's disease that incorporates endoscopy as a coprimary endpoint, reflecting the necessity for objec-tive assessment of disease activity. Overall, Risankizumab represents an expansion of our therapeutic options in Crohn's disease with proven effectiveness in biologic treatment naïve as well as exposed patients.


Identical units of exponential failure time distribution are subjected to accelerated life tests under different inter-related random environments. In a Bayesian setting, we investigate the asymptotic properties of the posterior moments of the unit failure rate, and we also study the asymptotic properties of the predictive mean of the unit lifetime. Then, we examine the Laplace transform of failure rate posterior distribution. The use of the developed methodology is demonstrated by an application.


The low molecular mass gelator, tetraoctadecylammonium bromide, can be
removed from polymerized gels of methyl methacrylate or styrene to leave
mesoscopic channels with submicrometre diameters.


A monitoring program and main function software design and implementation of a multi-function digital-synthesized signal source are developed. Its key properties and its systematical composition, designs of the monitoring program and function modular program are described. The monitoring program is in accordance with display practice and process, by which the display, storage and process of preset data are provided, and input data are gradually displayed based on function setting, and operational problems caused by the complex system functions are greatly simplified by a friendly man-machine interface.


AFA 3G Gd rod is indispensability part of assembly,through the technical research of the top end plug welding of M5-alloy,Analyzing the main reason of the welding deficiency and give the solution.


ABSTRACT Higher mode surface wave theory is used to model the vertical component Lg wave observed in eastern North America at regional distances. Tests of the model are made to determine whether it is capable of describing empirical spectral scaling laws, spatial attenuation, and peak time domain Lg amplitudes. It is found that a simple crustal model and a rough estimate of crustal QB are all that are required to accomplish this. Good results are obtained if the average crustal Qp is equated to the coda Q of the same frequency. INTRODUCTION The Lg wave is a wave observed on short-period seismograms of local and regional seismic events which travels with a group velocity of approximately 3.5 km/sec in the Central United States. It is usually the largest arrival on the seismogram, which makes it suitable for defining a magnitude scale (Nuttli, 1973; Herrmann and Nuttli, 1982). As part of developing the magnitude scale, there have been many studies on the spatial attenuation of the Lg wave (Nuttli, 1973; Street, 1976; Bollinger, 1979; Singh and Herrmann, 1982). The Lg wave is usually thought of as a superposition of higher mode surface waves propagating within the crustal wave guide. Herrmann and Nuttli (1975a, b) attempted to deterministically model observed Lg amplitudes in terms of focal mechanism, focal depth, and seismic moment using surface wave techniques. They were limited by their inability to compute surface wave eigenfunctions at frequencies greater than 0.5 Hz. However, their results were encouraging. Harkrider (1979), drawing upon the work of Apsel (1979), discovered a way to compute surface wave energy integrals of the higher modes very precisely. Bache


Judith Anderson (1897–1992) is best remembered for her now-iconic performance as the terrifying housekeeper Mrs Danvers in Alfred Hitchcock's Academy Award winning film Rebecca (1940). But it may c...


The preparation and properties of a unique new class of polymers containing polyhedral borane cages as part of the backbone polymer chain are described. The synthesis of polyamides, polyesters, polyureas, and polyurethanes proceeds from suitably chosen B10 and B12 polyhedral borane dicarbonyls, diols, and diisocyanates by typical condensation polymer techniques. Each complementary monomer may be a borane compound, but more often higher molecular weight products are provided when one monomer is a conventional organic reagent such as an aromatic diisocyanate. The polyamides prepared from 1, 12-B12H10(CO)2 and organic diamines were crystalline and soluble, but molecular weight were limited because the amidation reaction was reversible and/or the amide linkage could be split by nucleophilic attack by some solvents. The polyurethanes prepared from Na2B12H10(OH)2 and aromatic diisocyanates were high molecular weight and relatively more stable. Clear, colorless, tough films were prepared. These polymers were soluble in many polar solvents and exhibited typical polyelectrolyte behavior.


Using qualitative methods, we examined 12 patients' experiences with combining lă'au lapa'au (Hawaiian herbal healing) and Western medicine. Participants felt a higher degree of connectedness and understanding in their relationship with their healer than with their physician, and they felt that healers took more time to listen and clearly explain diagnoses. Lă'au lapa'au was more likely than Western medicine to incorporate a spiritual and prayer component, lead to improvements in cultural and personal identity, and foster feelings of connectedness to the land and Hawaiian values.


The Galicia-north Portugal Euro-region looks like a future space for university students in Portugal and Galicia. Our research, which is supported by de Spanish ministry of education and science, is about the knowledge they have of it. In it, we present our findings that will be used to develop a communications strategy that can empower this European structure.


Dynamic Network Actor Models (DyNAMs) assume that an observed sequence of relational events is the outcome of an actor-oriented decision process consisting of two decision levels. The first level represents the time until an actor initiates the next relational event, modeled by an exponential distribution with an actor-specific activity rate. The second level describes the choice of the receiver of the event, modeled by a conditional multinomial logit model. The DyNAM assumes that the parameters are constant over the actors and the context. This homogeneity assumption, albeit statistically and computationally convenient, is difficult to justify, e.g., in the presence of unobserved differences between actors or contexts. In this paper, we extend DyNAMs by including random-effects parameters that vary across actors or contexts and allow controlling for unknown sources of heterogeneity. We illustrate the model by analyzing relational events among the users of an online community of aspiring and professional digital and graphic designers.


This study aims to identify the effect of using a STEM-oriented (Science, Technology Engineering & Mathematics) teaching program in teaching mathematics on critical thinking skills among high school students in the Riyadh educational region in the Kingdom of Saudi Arabia. The sample of the study consists of (88) male and female students selected randomly from the "Advance Schools for Smart learning" in Riyadh city, where the semi-experimental approach is used. The results of the study show that there are statistically significant differences between the averages of the degrees of analysis skill, induction skill, reasoning skill, skill of conclusion, and evaluation skill in favor of the experimental group. The results also showed a statistically significant difference between the mean scores for the analysis skill, the induction skill, the reasoning skill, the conclusion skill and the evaluation skill for the benefit of the experimental group. The results also show a statistically significant difference between the mean scores for the scale skills as a whole and for the benefit of the experimental group. The results of the study show that there are no statistically significant differences between the mean scores of the critical thinking test skills and the total score attributed to the gender variable (male and female). The study recommends adopting the STEM approach in teaching science, technology, engineering and mathematics subjects, and redeveloping and building the content of science and mathematics curricula for the secondary stage through relying on science standards for the next generation, and working on adopting a special curriculum to teach the STEM approach and include it in the next plan for general education stages.


In this paper, we propose a novel SQL guided pre-training framework STAR for context-dependent text-to-SQL parsing, which leverages contextual information to enrich natural language (NL) utterance and table schema representations for text-to-SQL conversations. Concretely, we propose two novel pre-training objectives which respectively explore the context-dependent interactions of NL utterances and SQL queries within each text-to-SQL conversation: (i) schema state tracking (SST) objective that tracks and explores the schema states of context-dependent SQL queries in the form of schema-states by predicting and updating the value of each schema slot during interaction; (ii) utterance dependency tracking (UDT) objective that employs weighted contrastive learning to pull together two semantically similar NL utterances and push away the representations of semantically dissimilar NL utterances within each conversation. In addition, we construct a high-quality large-scale context-dependent text-to-SQL conversation corpus to pre-train STAR. Extensive experiments show that STAR achieves new state-of-the-art performance on two downstream benchmarks (SParC and CoSQL), significantly outperforming previous pre-training methods and ranking first on the leaderboard. We believe the release of the constructed corpus, codebase and pre-trained STAR checkpoints would push forward the research in this area. For reproducibility, we release our code and data at https://github.com/AlibabaResearch/DAMO-ConvAI/tree/main/star.


This article describes the need for China's rural environmental improvement and research progress,and proposes the various modes of rural environmental comprehensive improvement.Based on grading and classification of needed technologies,in accordance with the principle of local conditions and being user-friendly,a technologies database system is designed using the Microsoft Visual Studio 2010 and Office Access 2007 software.In future,the perfected system could provide scientific support to the rural environment planning and implementation activities.


The article addresses E. Durkheim's, R. Merton's anomie theories and the institutional anomie theory of S. Messner and R. Rosenfeld. The focus of the article is on how social structure is applied within these anomie theories and how it advances from a secondary topic in Durkheim's work into a key element of Merton's theory. I also address the shortcomings that Messner and Rosenfeld's institutional anomie theory has due to the lack of development of the issue of social inequality. Addressing the relationship of anomie and social structure helps show an alternative prospect to analyze and compare anomie theories as well as enables to reveal broader possibilities of application of social structure to studying anomie in contrast to the widespread empirical practice in anomie studies to restrict the social structure to income, social status, etc. (as Srole 1956, Dean 1961). According to Durkheim's approach, the social structure adjusts people's aspirations to a normal level for each social class. In Merton's view, in the situation of overemphasis of goals of success the social structure itself creates the strain for the lower social class representatives to deviate. Messner and Rosenfeld on the contrary claim that all societal layers have the strain to anomie due to the dominance of the economy over other institutions. Social structure has a most important role in Merton's theory. It also demonstrates a serious shortcoming in the institutional anomie theory: if one assumes the dominance of monetary goals at the institutional level, it should lead at least to inequality at the level of the institutes for different population groups: ones will have the opportunity to take care of own children and give them traditional education, others won't. Interesting to note, the issue of the normative regulation, which works, according to Durkheim, via the social structure is not addressed by other theories. Merton analyzes a situation of a normative conflict between the goals and the means, but not anomie (Gofman 2013, pp. 31-32). The problem of social regulation is hardly an issue for Messner and Rosenfeld: regulation should be constituted by institutes. Thus, in the situation that those are dominated by economy, there is a laissez-fair principle reigning in the society. Moreover, the usage of ano-mie by the authors seems to serve as a means for the institutional theory as a macro-level theory to separate itself from the strain theory, which is in terms of Messner and Rosenfeld a micro-level perspective.


The notion of Task/Technology Fit (TTF) posits that as the degree of overlap increases between the task domain, and the ways in which the capabilities of an information system (IS) are suited to activities within that domain, performance gains experienced via use of the IS should also increase. This research proposes an expanded TTF model that is applicable to the context of Knowledge Management (KM) and Knowledge Management Systems (KMS). In particular, additional individual, technological, and social factors and interrelationships between these factors could provide greater explanatory power of IS user behaviors, perceptions, and outcomes within the realm of knowledge work. A mixed-method field study approach was employed at a large government organization, currently in the process of developing and fielding a new KMS to support knowledge-intensive work, to investigate the underlying factors and relationships described within an expanded "KMS Fit" model. Results suggest that the foundational mechanisms described by the TTF model may in fact change within KM contexts. In particular, the inherently social characteristics of knowledge-based work were found to play a very important role in determining the degree of fit relative to a KMS. Moreover, the social ecology within the organization was found to have significant impact on KMS Fit. Results of this research further reinforce the notion that KMS may be a unique subset of IS and that traditional IS models (such as TTF) should be updated or tailored to reflect the social nature of knowledge-based work and knowledge management. https://doi.org/10.34105/j.kmel.2009.01.010


Adsorption of phenol from wastewater by activated carbon fiber adsorption was studied through static and dynamic test, the adsorption isothem was determined, the effects of the dosage of activated carbon fiber, the mass concentration of phenol, and the flow velocity through the resin column on the adsorption were investigated. The results indicated that the dynamic adsorption capactiy of activated carbon fiber on phenol was 256 mg/g; with the increase of the dosage of acitivated carbon fiber, the stable time of treated water become longer; the higher the mass concentration of phenol was, the shorter the time of penetrating would be; the faster the flowing velocity through the resin column was, the shorter the time of penetrating would be; the adsorption capacity of the saturated activated carbon fiber after be regenerated almost remained constant.


Objective To evaluate the efficacy and safety of butyl- phthalide injection in the treatment of acute cerebral infarction. Methods From January 2013 to September 2013,43 patients with acute cerebral infarction in our hospital were randomly divided into two groups,the control group received routine therapy,the treatment group on the basis of conventional treatment received Butylphthalide injection treatment,0.1,bid,for 21 days. Two groups of patients were assessed with NIHSS on admission,10 d and 21 d after treatment, and the modified RanKin scale(mRS) was used to evaluate the efficacy of treatment 21 d after treatment,and at the same time we observed the related adverse reactions. Results The nerve functions of 2 groups of patients were recovered after treatment,the nerve function of butylphthalide group had better recovery than the conventional treatment group(P0.05),and also the effective rate of butylphthalide group was higher(P0.05). Conclusion Butyl phthalide injection could obviously improve neural function in patients with acute cerebral infarction,is has good effect and safety,so it is worthy of clinical application.


Abstract : Mutations in mitochondrial DNA (mtDNA) are frequent in prostate cancer and they seem to occur early during prostate malignant transformation. Depletion of mtDNA in prostate cancer cells has been linked to acquisition of androgenindependence, progression to an invasive phenotype that is resistant to conventional chemotherapies, as well as induction of epithelial-mesenchymal transition leading to cancer metastasis. Using long-range genomic polymerase chain reaction, large deletion of mtDNA can be detected in prostate cancer tissues but not benign or normal prostate tissues. Noticeably, our study excludes the germ-line origin of the mutant mtDNA pattern in prostate cancer patient through analysis of the blood of the corresponding patient. Our data conclude that mtDNA deletion is due to carcinogenesis process in somatic prostate cells. In addition, our data have unveiled the molecular alteration in prostate cancer cells resulted from mtDNA deletion. For example, Skp2 protein elevation is often associated in prostate cells with loss of mtDNA. Also, the presence of Skp2 expression can decrease the expression of BRCA2 protein as an early biomarker of prostate neoplastic transformation, which is due to BRCA2 proteolysis.


Field survey was conducted in Singrauli coalfields to detect the suitable woody plant species for revegetation of coal mine spoils. Of the eleven woody species reported, the leguminous Acacia catechu and Butea monosperma and non-leguminous Adina cordifolia, Baswellia serrata, Holarrhena antidysenterica, Nyctanthes arboe-tristis and Woodfordia fruticosa are the potential woody species for the revegetation of coal mine spoils in a dry tropical environment.


There are moments in the life of a nation where the hand of God is clearly visible -- or so it seems. The years 1870 and 1871 provided many such moments, notably when France went to war against Germany and suffered defeat, invasion, and occupation on a scale surpassed only in 1940. The Catholic episcopate interpreted these cataclysmic events in terms at once political and providential, terms drawn ultimately from Catholic discourse on 1789. Defeat was a sign of divine judgement, the condemnation of a nation fallen from grace. France was invited to imagine a different past, a different history, a different national story, one that would have led to, and might still lead to, a different outcome for France. This story would provide a prescriptive guide for national reconstruction after 1870. I propose to examine certain artifacts of the crisis of 1870, artifacts that define the emblems, vocabulary, and script for Catholic nationalism through the Great War and beyond. And since we are here to honour James Leith and recognize his influence on the study of political culture, I propose to emphasize the spatial, "built," and iconographical features of my topic. My aim is to show how a specifically Catholic political culture was sustained and propagated in the nineteenth century, how this culture was embodied in certain votive churches dedicated to the Sacred Heart of Jesus, and finally how this culture reinforced prevailing discourses on counter-revolution in the Vend6e and the moral status of the Revolution. James Leith showed us Temples of Reason, I'm inviting you to visit Temples of Memory.(2) I The most famous of votive churches of 1870-71 would be the Sacre-Coeur de Montmartre, but that project was derivative of several provincial projects which antedated it.(3) In fact, the vow to build the Sacre-Coeur de Paris was made in Poitiers, not Paris, by Alexandre Legentil, a devout Parisian bourgeois who had fled the capital before the advancing Prussian troops. His piety and his perception of French decadence inspired his project for Montmartre, but so did events all around him. Throughout the west of France, the classic response to the crisis of 1870 was a vow to the Sacred Heart of Jesus and the construction of a church, a votive church. embodying and fulfilling the vow. Among the first dioceses to do so was Angers, led by its bishop.(4) Anger's church differed in significant ways from the Sacre-Coeur de Montmartre, notably in that it was to serve not only as a votive church, monumental in intent, but also to fulfill a pastoral need in a city whose population had outgrown its parish churches. The Angers church was begun sooner than the Paris project (no question of an architectural concours here) carried out on a far less grand scale and, remarkably, completed on schedule.(5) It was consecrated by Monseigneur Freppel, bishop of Angers, on 30 June 1878.(6) Making sense of sacred art and architecture can be tricky, especially when one wants to make assertions about sponsors's intentions. No such problem exists for the Angers church, however, given that the plan for the sacred art in the church was laid out in a memo drafted by the pastor of the parish and a copy of this lengthy memo can be found in the diocesan archives.(7) Why was such a plan made? Such programmes promote coherence in the sacred art for a church and they also minimize the influence of wealthy patrons, whose offers of money might come with strings attached, notably with respect to the style and content of sacred art. The problem was not a new one. Clergy in thirteenth-century Chartres faced similar challenges.(8) The Angers document is a precious one because it shows how the art in the church is organized around the devotion to the Sacre-Coeur but also because it reveals clerical eagerness to lay out a programme to which patrons would have to submit. Iconography was to be under clerical control. What, then, are the features of this artistic programme? …


We report a microplate-sized integrated perfusion culture microchamber array chip for high throughput drug dose response assays. The microchamber array chip was equipped with a pressure-driven interface, in which solutions were delivered into the microfluidic network by pneumatic pressure, and with a serial dilution microfluidic network, which generated a logarithmic concentration profile. The microchamber array chip is composed of an array of 384 microchambers for parallel quadruplicate assays using 12 drugs with 8 varying concentrations. The perfusion culture microchamber array chip, with its simple interface and well-designed microfluidic network, will likely become an advantageous platform for future cell-based assay.


The Share Economy' by Martin L. Weitzman has reaped favorable comments from several distinguished sources. Robert Solow has termed it "a marvelous book," James E. Meade views the book as "important, stimulating, readable, and persuasive," and the New York Times has provided editorial praise. Because of the support it has received and because of the importance of its goal-conquering stagflation-we have selected this book for special review by distinguished representatives of academia, labor, and management. In recent decades, industrialized economies have been troubled with stagnation, the combination of stagnation and inflation. Weitzman argues that the traditional macroeconomic weapons, such as fiscal policy, are inadequate to deal with stagnation because they ignore im-iportant micro behaviors. The main culprit is the wage-payment system, which relates compensation to some measure, such as a fixed dollar amount, whose value is independent of the firm's well-being. Most sales are accounted for by firms that are "competitive monopolists" in their product markets, which means that prices tend to be a fixed markup over wages. Because wages


The public health functions of surveillance of health status and needs population-based health education and promotion screening and standards development and quality monitoring are important to the health care of US women over their life span. This report presents a table suggesting ways the US Public Health Services "10 essential public health services" can be operationalized for selected issues specific to women: prenatal care breast and cervical cancer and partner violence. The proliferation of organizational units within government that are focused on womens health creates challenges for the coordination and integration of efforts. The US Department of Health and Human Services is in a position to bring together constituency groups concerned with womens health maternal health and child welfare to determine how preventive health services can be coordinated at the individual and community system levels.


: This paper presents a quasi-diachronic analysis of the development in negation system of three different Chinese varieties, namely mainland Mandarin, Hong Kong Cantonese, and Gaozhou Cantonese – an unstudied variety spoken in Maoming. I argue that the form and distribution of the negators méi (y ǒ u) , mou 5 , and mau 5 in these varieties respectively, are strongly connected to the development of the existential predicate y ǒ u/jau 5 'have', a key component of Chinese negators. Supported by preliminary typological findings, the development in form of the negator NEG-HAVE concurs with the BE/HAVE auxiliary development as argued in Freeze (1992) and Kayne (2000). Cross-dialectal variation in negator distribution is attributed to the development of the existential predicate along the proposed pathway of existential > possessive > aspect. This analysis can explain the split negation system found in Mandarin and HK Cantonese, where méi (y ǒ u) and mou 5 are used specifically for perfective contexts, in the minimalist framework of Agree and incorporation.


In the reaction of 2-cyanomethylbenzmidazole and their 1- and 5-methyl derivatives with aromatic isocyanates and isothiocyanates, 23 N-arylamides resp. thioamides of benzimidazolyl-2-alpha-cyanoacetic acid were obtained. The structure of the newly compounds (Table 1) was confirmed by NMR and IR spectra. Some of these shown moderate tuberculostatic activity in vitro.


AIM OF THE STUDY:
To estimate the levels of 14-3-3η levels in rheumatoid arthritis patients and establish its role in the pathogenesis and diagnosis of the disease.
METHODS:
The study design was prospective, randomized, single blinded, case control study with 60 patients and 30 controls. The patients were subdivided into two groups as group1: rheumatoid factor positive patients and group 2: rheumatoid factor negative patients.
14-3-3 eta protein were estimated in the patients and the control using ELISA method. And other parameters like rheumatoid factor, ACPA, CRP, ESR were estimated and results were evaluated.
RESULTS:
It was observed that the mean value of 14-3-3 eta protein of cases and control resulted to significantly different (p<0.05) and the mean value of RF positive cases, negative cases and controls also resulted to be statistically significant (p<0.05). Positive correlation was established between RF and 14-3-3η protein.
CONCLUSION:
14-3-3η protein along with other existing markers has a significant value in the diagnosis of rheumatoid arthritis for earlier diagnosis and prevention of deformity.


Although distributed ledgers frequently are viewed as a revolutionary technology that could transform many markets, the technology has not yet received wide-scale business adoption. This may be due in part to a lack of use cases for which the decentralized and distributed features of distributed ledger technology (DLT) are optimal. But payment directories (known in certain markets as registries), which facilitate the lookup of payments-related information, may be a use case that has specific challenges that take better advantage of these features than other use cases explored by businesses to date. Directories that support routing of information to support payments like aliases for peer-to-peer payments and business-to-business e-invoices may benefit from the use of DLT. DLT allows market participants to maintain and to protect localized information without the competitive, operational, and technical challenges of a centralized database.


ABSTRACT Investigations in the 1990s evaluated the influence of breathing assemblies on respiratory variables at rest and during exercise; however, research on new models of breathing assemblies is lacking. This study compared metabolic gas analysis data from a mouthpiece with a noseclip (MOUTH) and a face mask (MASK). Volunteers (7 males, 7 females; 25.1 ± 2.7 years) completed two maximal treadmill tests within 1 week, one MOUTH and one MASK, in random order. The difference in maximal oxygen consumption (VO2max) between MOUTH (52.7 ± 11.3 ml · kg−1 · min−1) and MASK (52.2 ± 11.7 ml · kg−1 · min−1) was not significant (P = 0.53). Likewise, the mean MOUTH–MASK differences in minute ventilation (VE), fraction of expired oxygen (FEO2) and carbon dioxide (FECO2), respiration rate (RR), tidal volume (Vt), heart rate (HR), and rating of perceived exertion (RPE) at maximal and submaximal intensities were not significant (P > 0.05). Furthermore, there was no systematic bias in the error scores (r = −0.13, P = 0.66), and 12 of the 14 participants had a VO2max difference of ≤3 ml · kg−1 · min−1 between conditions. Finally, there was no clear participant preference for using the MOUTH or MASK. Selection of MOUTH or MASK will not affect the participant's gas exchange or breathing patterns.


The literature has focused on motives to explain remittance behavior. But as nonanonymous transfers, remittances are apt to be influenced by giving norms as well. We formulate an empirical specification that takes account of remittance motives involving workerhousehold pairs. We find that altruism dominates the exchange motive among overseas workers who are likely to be the primary breadwinners of their recipient households. We also find that, in the subsample in which overseas workers are likely to be secondary breadwinners, (a)household labor income is an endogenous explanatory variable and(b) the error covariance of the householdincomeandremittanceselectionequationsispositive.Apossiblereasonfor(a)isthat secondarybreadwinnersusehouseholdincomeasanimperfectsignalofopportunitycostorto detectunobservedeffort,i.e.,moralhazard,ingeneratingincome.Asfor(b),wesurmisethatit indicates the presence of incentivecompatible mechanisms against moral hazard. On giving norms,wefindthat,insamplesthatincludeoverseasworkerswhoaresecondarybreadwinners, remittance amounts are afflicted with negative selectivity. We present evidence that this is consistentwithFilipinogivingpractices,inwhicheveryonegivesbutinmodestamounts.


With the reform and opening to the world and the development of socialist market economy, there are more and more impermissible behaviours and losses of standards, in China.so it is necessary to establish new socialist economic ethic standards. The establishment is to be based on the internal need of socialist market economy. the three - beneficial - to evaluation measurement and the traditional need of transition.


Gas puff target experiments as performed with the POSEIDON plasma focus (PF) device enable partial decoupling of the initial PF phases from the final compression phase. The influence of deuterium and argon gas puffing on pinch dynamics, neutron and X‐ray emission in 135 kJ discharges was investigated. Various diagnostic techniques including optical streak and framing as well as Schlieren and X‐ray pinhole photography, neutron, X‐ray and electron beam detection were applied. It was found that a large plasma focus can be operated in a controlled way with the injection of an additional gas target. Gas puffing causes a rise in the level of turbulence and results in an increased tendency of hot spot formation. With deuterium gas puffing the neutron yield could be increased by at least a factor of 1.3.


Abstract: Endoscopic biopsy specimens of the remnant gastric mucosa (and of the stomal mucosa in particular) were investigated in 219 patients who had received subtotal gastrectomy for gastric cancer. Dilated glandular lumina (glandular dilatation) and curved ducts (irregular glandular structure) were detected significantly more freguently in the group gastrectomized long before, or by Billroth II resection, than in those treated recently, or by Billroth I resection. DNA histograms showed a distribution of epithelial cells from the remnant gastric mucosa which was somewhat different from the normal histogram. The occurrence rates of polyploid cells were significantly higher than normal, and tended to increase in the same individuals with advancing time after gastrectomy. These observations suggested that the pavticulav environments of the gastric remnant might have nonphvsiologic influences upon the gastric mucosa, although further studies are essential for the clarification of the possible relationship of these environments to oncogenesis in the remnant stomach.


In a search for further examples of Heusler-type alloys, ferromagnetic alloys were found near the composition Ni2MnIn, Ni2MnGa, Co2MnGa, Pd2MnSb, and PdMnSb. The first four alloys are tentatively identified as having the L21(Heusler)-type structure; PdMnSb, the Cl1-type structure. Previous work has indicated that ferromagnetism in these types of alloys is associated with Mn-Mn distances in the range 4.17–4.37 A. The present work indicates that ferromagnetism persists with Mn-Mn distances as small as 4.08 A (Co2MnGa) and as large as 4.42 A (PdMnSb); and that ferromagnetism disappears if the Mn-Mn distances become too large. Pd2MnSb, with Mn-Mn distance 4.55 A, is only feebly magnetic at room temperature.


Three taxa of the ostracode genus Loxoconchella are described and illustrated. Of these, two species - L. multibullata n. sp, and Loxoconchella sp. - are recorded from the Quilon beds (Lower Miocene) of Kerala and one species - L. dorsobullata okhaensis n. subsp, - from the shallow water near Okha Port, Gulf of Kachchh.


Objective Methods To examine whether peripheral burn injury in rats elevates prostaglandin EZ in the central nervous system and to determine where in the central nervous system enzymes responBible for prostaglandin E2 synthesis are expressed.Subjects:Sprague-Dawley rats.Interventions:Rats received either approximately 25% fullthickness burn injury or sham treatment.At 36 hrs after the injury,the cerebrospinal fluid was sampled to measure prostaglandin E2,and the brain and the spinal cord were sampled for immunohistochemical detection of cyclooxygenase-2 and microsomal-type prostaglandin E2 synthase,enzymes that are responsible for prostaglandin E2 production.Measurements and Main.Results The prostaglandin E2 concentration in the cerebrospinal fluid was significantly elevated in the injured rats,and this elevation was suppressed by a cyclo-oxygenase-2-specific inhibitor,NS398.Only in the injured rats,cyclooxygenase-2 and microsomal-type prostaglandin E synthase proteins were detected in vascular endothelial cells throughout the central nervous system with no regional difference.A double-immunofluorescence study revealed that cyclooxygenase-2 and microsomal-type prostaglandin E synthase were coexpressed in the perinuclear region of the endothelial cells.Conclusion These results indicate that peripheral burn injury induces cyclooxygenase-2 and microsomal-type prostaglandin E synthase in endothelial cells of the central nervous system.These enzymes likely elevate the cerebrospinal fluid concentration of prostaglandin E2,a prostanoid that,in turn,activates prostaglandin E2 receptors on the central nervous system neurons involved in the general symptoms following burn injury.


The curing kinetics of different amounts of nano-Al2O3 modified epoxy matrix was investigated by DSC.According the DSC results,the curing kinetics parameters of different composites were calculated by Kissinger and Crane method and the relationship between curing degree and temperature was also studied.The results showed that the initial and end curing temperature were decreased and the curing time was shortened by the adding of nano-particles.The exothermic peak temperature and activation energy of the curing reaction were decreased with the increasing of nano-Al2O3 content in composites,but the reaction frequency factor and reaction order were almost invariant.


Considering parametric uncertainties and unmodeled disturbances in hydraulic systems, this paper presents an asymptotic adaptive motion control scheme by adopting full state feedback. To accomplish this study, a novel parameter adaptive law based on both parametric estimation errors and tracking errors is developed to deal with parametric uncertainties of hydraulic systems, which can attenuate the major of parametric uncertainties and enhance the tracking performance. Then a composite robust integral of the sign of the error (RISE) feedback controller is employed to restrain the rest of parametric uncertainties and unmodeled disturbances. The developed continuous RISE-based controller is free of chattering, which is beneficial to practical implementation. Stability analysis indicates that the proposed method guarantees an excellent asymptotic tracking performance even in facing with time-variant disturbances and parametric uncertainties. Comparative simulation results are obtained to verify the high-performance nature of the proposed control strategy as well.


The USEPA Part 503 rule did not directly specify the amount of sludge-borne P that can be applied but allowed application rates based on the recommended N requirement of a crop. Monitoring of long-term application of biosolids is important to protect both soil and water quality. Biosolids and ammonium nitrate were annually applied for 13 yr to winter wheat at six plant available N (PAN) rates: 0, 45, 90, 180, 269, 536 kg N ha -1 yr -1 . Biosolids application did not increase soil pH but increased levels of total C, total N, NH 4 -N, NO 3 -N, and electrical conductivity (EC). Soil concentrations of Cd, Cu, Pb, Mo, and Zn were greater in biosolid-treated plots but were <24% of their respective cumulative pollutant loading rates. Application of biosolids increased plant micronutrient B, Cu, Fe, and Zn concentrations. The addition of biosolids to the Norge soil (fine-silty, mixed, active, thermic Udic Paleustoll) increased Mehlich 3 plant available P (M3P) and water soluble P (WSP) and these P levels were well correlated with biosolids application rate. Application of biosolids at rates of ≥2 times the recommended agronomic rate of 90 kg PAN ha -1 resulted in M3P concentrations that exceeded an environmental threshold of 200 mg kg -1 established by the USDA-NRCS for the land application of manures in Oklahoma non-nutrient limited watersheds. Significant relationships were found between the ammonium oxalate P saturation index (PSI ox ) and M3P as well as between PSI ox and WSP. It appears the repeated long-term application of biosolids above the N agronomic rate should be avoided and application should be based on other criteria such as an agronomic P threshold, an environmental P threshold, or a P site index.


A transconductance-amplifier-capacitor sinusoidal oscillator is introduced. The circuit requires only two operational transconductance amplifiers (OTAs) and two grounded capacitors. The frequency of oscillation is linearly tunable over a wide frequency range. >


The failure strain level in a single point incremental forming (SPIF) process is found to be much higher than that in the traditional stamping process. Based on the assumption that forming limits in SPIF are dominated by fracture failure, the Oyane ductile fracture criterion is introduced in this paper to predict the fracture initiation site, and hence the forming limit, given the stress and strain values obtained from finite element simulations. The predicted results compare well with those obtained from the SPIF experiments. Furthermore, this fracture criterion is used to study the size effects in SPIF. Analytical equations are derived to comprehensively consider the effects of design and process parameters on sheet formability including sheet thickness, tool diameter, and incremental depth. Previously published experimental data is used to verify the feasibility of the proposed size effect equation.© 2008 ASME


Archaeological excavations carried out from 1990 to 1993 on ile aux Basques (Quebec), in the middle of the St Lawrence River, have revealed objects testifying to a Basque presence as early as the sixteenth century. This discovery is considered a confirmation of long repeated oral narratives that have associated Basque fishermen with the founding of the city of Trois-Pistoles. It was decided to exhibit these objects in an interpretation centre with an adjoining fronton, for playing Basque pelota, and a restaurant. This article examines what is involved in this transfer of objects from the island to the museum. How were these artifacts changed into identity markers of a whole region, of which the only referent to Basque culture is a tenacious myth and an island situated six kilometres offshore? Resume
 Entre 1990 et 1993, une equipe d'archeologues realise des fouilles au milieu du Saint-Laurent, a l'ile aux Basques (Quebec). Elle y decouvre des objets qui attestent d'une presence basque des le XVIe siecle. Cette decouverte est percue comme une confirmation de ce que disent, depuis longtemps, les recits de tradition orale qui associent les pecheurs basques a la fondation meme de la ville de Trois-Pistoles, en des temps recules. Il est alors decide d'exposer ces objets dans un centre d'interpretation qui jouxtera un fronton de pelote basque et un restaurant. L'article propose d'etudier ce qui s'est joue dans ce transfert des objets, de l'ile vers le musee. Comment ces artefacts ont-ils ete eriges en marqueurs identitaires de toute une region, qui n'a d'autre referent a la culture basque qu'un mythe tenace et cette ile, a six kilometres des cotes ?


Intrauterine, nutritional supplements might benefit the growth retarded fetus.We studied the effects of gastric infusions of nutrients on umbilical uptake(Umb U)of amino N,glucose,lactate and O2 and on lower body blood flow,using 14 fetal lambs(126-138 days gestation,6-17 days post surgery)with indwelling femoral arterial (FA),umbilical venous(UV),cranial mesenteric venous(CMV)and gastric catheters.Seven received 2 hr infusions of 8.5%,L-amino acids (Travasol,10-25mg/kg/min)and seven received 20% glucose(14-38mg/kg/min),Umb U and intestinal uptakes were calculated from measurements of FA,UV and CMV whole blood nutrient concentrations and microsphere blood flow measurements,made twice before the infusions and 2-3 times in the 2nd hr.During amino acid infusions,the intestine absorbed amino N,at a mean rate equal to 45% of Umb U of amino N.Umb U of nutrients did not change but O2 uptake decreased (p<.05).When glucose was infused,the intestine absorbed glucose, at a mean rate equal to 42% of Umb U of glucose.Umb U of amino N, lactate and O2 did not change.Umb U of glucose decreased,in inverse proportion to the rise in FA glucose concentration(p<.01). During the infusions,umbilical blood flow decreased(mean of 12%, p<.005),while intestinal blood flow increased(mean of 41%,p<.05). Conclusions: Fetal gastric supplementation with amino N is possible.Glucose supplementation is limited by the decrease in Umb U of glucose which occurs,when fetal glucose concentration rises.


Introduction: There are different combinations of neoadjuvant chemotherapy (NCT) to treat locally advanced breast cancer (LABC); treatment with cytostatics drugs make it a costly concern, by establishing economic differences in the consumption of health care resources. Objective: To compare the cost-effectiveness of two NCT strategies. Patients and method: it was made a cost-effectiveness analysis (CEA) of two treatment schemes (4FE100C vs. 6FE100C) in patients with clinical stage III breast cancer, each cohort included 48 patients. Effectiveness parameter: pathologic complete response (pCR). Differential cost: incremental cost-effectiveness ratio (ICER) using a Markov's model. Results are expressed in terms of incremental cost per extra unit of effectiveness. Costs were expressed in Mexican (MXN) pesos ($) as of 2005; these were calculated under the perspective of public health care system (SSP, for its acronym in Spanish) denominated IMSS, with a 3 to 4 years analytical horizon. In order to determine the robustness of the results, a sensitivity analysis was carried out by modifying only the medical direct costs with a 3% discount rate. Results: The use of 6FE100C offered greater effectiveness compared against 4FE100C; the medical direct cost of only the cytostatic drugs for NCT with 6 FE100C and 4 E100C generated a cost per case of $30,467.00 MXN (€ 2,343.61) and $18,004.00 MXN (€ 1,384.92), respectively. The greatest unit price was given by epirubicin. The CEA demonstrated that the cost-effectiveness (C/E) was greater with 6 FE100C and the incremental cost-effectiveness ratio (ICER) showed that it was necessary to pay $11,765,925.42 MXN (€ 905,071.20) because it tells us how much it is paid additionally for every extra unit of effectiveness (pCR) which assumes 6 FE100C in front of 4 FE100C. The sensitivity analysis performed shows the robustness of the results. Conclusion: The 6 FE100C scheme is the strategy with better cost-effectiveness ratio and is the most efficient in the short run for treating LABC. *Corresponding author: Ramirez-Torres Nicolàs, MD, Department of Gynecologic Oncology, Gynecology and Obstetrics Hospital No. 3, National Medical Center La Raza, IMSS, Mexico, Tel: +(525) 55 57245900 ext. 23615; E-mail: email@example.com Received September 11, 2013; Accepted October 28, 2013; Published October 31, 2013 Citation: Ramirez-Torres NMC, Herrera-Abarca Jorge EDC, Chavez-Carbajal Jose FMC, Hernandez Valencia MDC (2013) Cost-Effectiveness Analysis of Neoadjuvant Chemotherapy with Intensive Dose of Epirubicin and Different Cycles in Patients with Locally Advanced Breast Cancer: 4 Fe100c Vs. 6 Fe100 C. Pharmaceut Reg Affairs 2: 113. doi:10.4172/2167-7689.1000113 Copyright: © 2013 Ramirez-Torres NMC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


A considerable amount of literature has been published on the relationship between ethno-religious conflicts and civil society in the post conflict countries. One such manuscript, "From Identity-Conflicts to Civil Society: Restoring Human Dignity and Pluralism in Deeply Divided Society" authored by Dr. Valentina Gentile, addresses several interesting theoretical perspectives on the complex dynamics of civil society development in a democratic transition, particularly referencing it to the divided societies. Her conceptualization is grounded on two main assumptions: the idea of multiple identities and the idea of a society where individuals are linked to each other by virtue of their plural affiliations. Gentile's analysis of culturalist and rational choice perspectives, with regard to the concepts of identity and conflict, is an important added value to this topic. The manuscript encompasses the understanding of civil society as a complex equilibrium among cultural, political and economic domains, from a historical perspective, incorporating many different accounts. The emphasis is placed on a deeper consideration of the idea of the individual's identity, actions and motivations in the context of the interrelations between civil society, conflicts and post-conflict democratic transition. The book is divided into four chapters. The first chapter offers a general introduction to the concepts of identity-conflicts, democratic values such as human dignity and pluralism, and civil society. The second chapter analyzes the notion of contemporary ethno-religious conflicts, in the light of the so-called de-essentialized concept of identity applied to conflicts. The third chapter gives a detailed account of the concept of civil society and the idea of 'civility', while the final chapter is devoted to testing the theoretical approaches on an actual case of post-conflict transition, the case of Bosnia and Herzegovina. Civil society, as described by Gentile, is a liberal reading of Hegelian conceptualization – an intermediate dimension between family and state, a bearer of specific cultural and historical developments, and of rights and values. Her analysis emphasizes political, economic and cultural features of Hegel's bourgeois society linked to the idea of multiple identities (p. 84). In this sense, civil society is defined as neither an autonomous public, nor a private sphere. Gentile follows Amartya Sen's conception of identity, and she identifies with the concept. It is referred to as the sum of plural affiliations, interacting with economic and political features in the context of internal conflicts. When considering the link between identity and violence (p. 45), Gentile suggests the presence of individualist and culturalist reductionism. Upon tackling culturalist and rational choice approaches, stemming from a primordialist understanding of identity (p. 30) and rationally constructed actions and ideas, she accepts an individualist-rooted understanding of violence, which does not underrate the role played by identity-based claims. From the philosophical point of view, two parts of the book deserve par-


With eight indica conventional,indica hybrid,japonica conventional and japonica hybrid rice as materials,the sensory evaluation of cooked rice in 11 different locations in indica rice growing region in China was carried out by two sensory evaluation methods(score method and equality range method).Results showed that the sensory score of the score method significantly varied with varieties and sites.However,the sensory score of the equality range method was significantly affected by variety irrespective of sites.Age and gender both have no significant effect on the sensory score using the equality range method.Tailand′s aromatic variety,Xiangwanxian 13,Liangyoupeijiu and Shanyou 63 were significantly different in sensory score,and the sensory evaluation values of cooked rice of the former three were corresponded to the grain ranking of national rice standard GB 1354.The sensory scores of cooked rice from indica rice growing region people were in accord with the acceptance degree of people in japonica rice growing region.It is suggested that the sensory standard rice sample should be chose in sensory evaluation and the equality range method can be adopted.


The corrosion behaviour of Q235 steel in sulfate-reducing bacteria(SRB) environment was studied with modern surface analysis technologies.Atomic force microscopy(AFM) and scan electron microscope(SEM) was applied to observe the morphology of microbial biofilm and corrosion appearance.X radial diffraction(XRD) and X photoelectron scan(XPS) was applied to analyze composition of the surface.The result showed that compact sulphide films were formed on the surface of Q235 steel and then microbiologically attached and formed biofilms during the process of microbiologically influenced corrosion with concentration cell mechanism.The corrosion of Q235 steel mainly presents pitting corrosion character.


A simple variant of the edge method to determine the presampled modulation transfer function (MTF) of digital imaging detectors has been developed that produces sufficiently accurate MTF values for frequencies up to the Nyquist frequency limit of the detector with only a small amount of effort for alignment and computing. An oversampled edge spread function (ESF) is generated from the image of a slanted edge by rearranging the pixel data of N consecutive lines that correspond to a lateral shift of the edge of one pixel. The original data are used for the computational analysis without further data preprocessing. Since the number of lines leading to an edge shift of one pixel is generally a fractional number rather than an integer, a systematic error may be introduced in the MTF obtained. Simulations and theoretical investigations show that for all frequencies up to the Nyquist limit the relative error ΔMTF/MTF is below 1/(2N) and can thus be kept below a given threshold by a suitable choice of N. The method is especially useful for applications where the MTF is needed for frequencies up to the Nyquist frequency limit, like the determination of the detective quantum efficiency (DQE).


The banking industry reports that false acceptance rates at ATMs are as high as 30%, which results in financial fraud of US $2.98 billion a year [21]. Roughly 4000 immigration inspectors at US ports-of-entry intercepted and denied admission to almost 800,000 people. There is no estimate of those who may have gotton through illegally. In other words, neither a PIN number nor a password is reliable. To partially solve these problems, the technology of biometric recognition has recently raised increasing interests. Biometrics is the science and engineering of using digital technology to identify or verify individuals based on the individual's unique physical, biological, and behavioral characteristics such as fingerprint, hand geometry, face, iris pattern, voice pattern, gesture, and digital signature [21]. This project asks you to develop and/or implement a personal identification system based on fingerprints. You are encouraged to finish the following tasks. (1) Investigate image enhancement algorithm based on the ridge direction to enhance input fingerprint images from a live scanner like Veridicom FPS110. (2) Investigate a robust fingerprint classification algorithm to classify fingerprints into 4∼5 types [18]. (3) Investigate an efficient minutiae matching algorithm using fingerprint classification for identification.


A method for manufacturing a holding bar (10) for a headrest, - Wherein a cylindrical steel bar (12) is bent into a shape with a first (14) and a second leg (16), characterized, that the bent steel rod (12) inserted into an injection mold, where the legs (14, 16) of the rod with plastic sleeves (18, 20) are extrusion-coated in order to reduce the weight of the support rod, wherein in the plastic sleeves (18, 20) locking slots (34, 36) are formed


Fusion PCR, which employs chimeric primers to generate PCR products with complementary ends in its amplifications, is a rapid and flexible method in joining different DNA fragments. This method can assemble DNA fragments without the treatment of restriction endonucleases and T4 DNA ligase. It offered a shortcut for the construction of homologous recombinant fragments. Through assembling three recombinant fragments successfully, fusion PCR procedure was improved and manipulation essentials of fusion PCR were described in detail. The results indicated that the improved procedure can assemble three or four fragments simultaneously, and the length of each fusion product is above 4.5 kb. The result recombinants were proposed to be use in further experiments, which structures had been confirmed by sequencing.


The COVID-19 disease, which was declared as a pandemic by WHO on the 11th of March 2020 has to date, infected over 38 million people worldwide. The medical community was mostly unprepared for the i...


Instrumental Enrichment (IE), an intervention program for developing the prerequisites of thinking and learning, is derived from Feuerstein's theory of structural cognitive modifiability. A basic a...


Kurt Culbertson, CEO of Design Workshop, along with Deanna Weber of the firm's Southern California office, Cal Poly alumni Steve Noll of the Lake Tahoe office and Gregg Way of the Santa Fe office, will direct design efforts for the Broad Street Village area of San Luis Obispo. The entire Landscape Architecture Department will come together to create an instantaneous 200-person design force for the San Luis Obispo community.


Silicon carbide coatings have been deposited on graphite specimens by thermal decomposition of dichlorodimethylsilane. The effects of flow variables, substrate temperature and gas composition, on the tensile strength of chemically vapor deposited silicon carbide coatings are discussed. The ratio H{sub 2}:(CH{sub 3}){sub 2}SiCl{sub 2} was varied from 4:1 to 6:1 at substrate temperatures of 1,100{degree}, 1,150{degree}, 1,200{degree}, and 1,250{degree}C. The strength of VCD SiC coatings was strongly dependent on the substrate temperature and the gas composition. Highest strength values were obtained at low temperatures (1,100{degree}) and low concentration ratios (4:1) of carrier/precursor gas. At 1,150{degree} and 1,200{degree}C, the curves tend to exhibit minimum strength at a specific ratio of carrier to precursor gas. The effects of substrate temperature and gas composition on the stoichiometry and structure of the SiC and its relation with the strength of the coatings are also discussed.


A 58-year-old woman with seronegative rheumatoid arthritis presented with low-back pain. Her medication included etanercept, low-dose prednisolone, and leflunomide. Two weeks earlier, she consulted her office-based orthopedic surgeon for acute-onset right-sided back pain, and an intra-articular triamcinolone injection into her right sacroiliac joint was administered. The procedure was done without imaging guidance. While her pain progressed, an additional pulse therapy with 35 mg prednisolone was initiated. Still without sufficient pain relief 3 weeks after the intervention, imaging was ordered. The initial pelvic survey did not show abnormalities, whereas a promptly obtained magnetic resonance imaging scan of the sacroiliac joints (Figs. 1A,B) showed erosions of the sacral bone (white arrowheads), abscess formation in the gluteus medius and iliopsoas muscles (white arrows), and


The 14.6 tex yarn spun by use of 100 % soybean protein fiber is of excellent performance.In this paper are introduced the processing flow and the key measures adopted in its various spinning process.Fiber transferring should be focussed in carding,properly drafting and weight setting in roving has to be made and hairiness and yarn fault ought to be minimized in spinning.


The characteristics of distributed Bragg reflector(DBR) cavity are analyzed. A narrow-linewidth single-frequency ytterbium-doped fiber DBR laser is fabricated. The laser is pumped by a semiconductor laser operated at 977 nm. Its output power reaches 4 mW and the lasing linewidth is less than 8 MHz (instrument resolution limited) at free wavelength of 1052.5 nm. Up to 20.4 nm(1036.1-1056.5 nm) continuous tuning is demonstrated from this DBR fiber laser operating in single longitudinal mode using a simple beam bending tuning technique for axial extension and compression. Over the full tuning range, threshold pump power and slope efficiency vary with laser wavelength.


The post‐Cold War era has seen the dual rise of the growing perception of the importance of biological weapons for deterrence, and the recognition of the necessity to control their proliferation. Dr Graham Pearson here charts the developments of recent years, assessing the greatest areas of concern and the steps taken to control these weapons. He looks ahead emphasising the need to face the reality that chemical and biological defence will continue to play an important pan in national security for the foreseeable future.


Abstract There has not been a major wheat stem rust epidemic in Canada since 1954. The detection of race TTKSK, with virulence to Sr31 and most other stem rust resistance genes in wheat, presents a threat to the wheat crop worldwide. Single disease resistance genes are usually effective for only several years before the pathogen changes genetically to overcome the resistance. To produce more durable resistance to race TTKSK, as well as to leaf rust and Fusarium head blight (FHB), we produced pyramided lines with several resistance genes. A population of 68 doubled haploids was produced from the hybrid 'AC Cadillac' (SrCad, Lr34)/'Carberry' (Lr34, Fhb1) × 'RL5405' (Sr33)/'Carberry' (Lr34, Fhb1). A total of 16 combinations of variable numbers of the four genes were recovered by marker assisted selection. The most notable combination with four of the genes was Sr33, SrCad, Lr34 and Fhb1. Two such lines were recovered. All pyramided lines with Lr34 and SrCad or Sr33 were resistant to race TTKSK, while two control wheat varieties 'Shaw' and 'Little Club' were susceptible. The two pyramided lines (SrCad-Sr33-Lr34-Fhb1) were relatively more resistant than the lines containing only one gene for stem rust resistance. The pyramided lines with Lr34 showed good resistance to leaf rust races 12–3 MBDS and TDBG. The pyramids with Fhb1 did not show a lowered expression of Fusarium head blight.


N. KENYON BROWN, 29, is an Associate Engineer with the Applied Physics Laboratory, specializing in software development for engineering-oriented computer systems. He began work in this field in 1965, having graduated from Virginia Polytechnic Institute with a Bachelor's Degree in Electrical Engineering. During his college years he participated in a cooperative program of industrial experience and served the Applied Physics Laboratory as an analog computer simulation engineer using the widely known EAI 231-R to solve aerospace simulations.


Introduction:  Anemia of chronic disease (ACD) is the second most common form of anemia after iron deficiency anemia. This type of anemia occurs in cases of chronic infections, inflammatory conditions, or neoplastic disorders and even in presence of enough iron and required vitamins. Some previous studies have suggested that periodontitis, as a chronic disease, is likely to be associated with this type of anemia. The aim of this study is to investigate the possible effect of non-surgical periodontal therapy on improvement of blood parameters. Methods: This study was performed on 36 male patients with chronic moderate or severe periodontitis (divided into case and control groups) and 18 men with healthy periodontium. Blood samples such as hematocrit, hemoglobin, MCH, MCHC, MCV and Ferritin were collected from participants. Then periodontal treatment was started for case group. Results: In the case group, there was a significant increase in hematocrit, hemoglobin, MCH, MCHC and MCV after 8 weeks of treatment and there was no significant decrease of Ferritin. No significant differences in blood parameters were observed in periodontally healthy and control groups. Conclusion: According to significant differences in some mentioned blood parameters after non-surgical treatment, it seems that periodontal assessment and subsequent therapy can be recommendable as an adjunctive part in overall treatment plan of anemic patients.


In order to establish a scientific transportation forecasting system and accurately get to know the forecasting theory in transportation demands,it is necessary to re-discuss the implications in the transportation demands and supplies.This paper,through demand functions and demand-supply balance theory,carries out a sensitive analysis on the relationship between transportation demands and price variations,and the relationship between transportation quality and demand variations.The authors find that the transportation demand is characterized by its gradation while the transportation supply is featured by heterogeneity,and that the recorded transportation volume and the future demands are restricted by supply-demand conditions,which should not be taken as equivalent.The results show that if the supply can meet the needs of demands,the existing forecating method can still be used.If not,the demand can be futher divided into price sensitive mode and quality sensitive mode.The paper,at last,by means of elastic analysis theory,observes the variation law of the relationship between supply and demand and forcasts the future increases.


F ormal protected area systems will always be insufficient to sustain biodiversity and ecosystem processes. The largest proportions of endangered ecosystems and rare species remain outside public conservation areas on private land, and the political and financial costs of strategic acquisitions of these areas for conservation estate are becoming unaffordable. Although biologists quite rightly continue to call for development of more comprehensive and representative reserve networks, the reality is that the coverage, connectivity, and size of protected areas will remain inadequate (Shaffer et al. 2002). Many authors and participants, as well as the conclusions, of the very comprehensive 30-year review of the Endangered Species Act (Scott et al. 2006) noted the continuing challenge and urgency of extending the conservation agenda more comprehensively across natural and working landscapes (matrix lands), most of which will remain outside any formal reserve system. New integrative approaches are needed. Landscape patterns provide a multiscalar "theater" in which humanecological interactions play out. The regional landscape context in which a new conservation agenda might be developed recognizes the fragmented matrix as a variety of patterns of not just ecosystems but human communities with various private lands or resource tenures, including agricultural and other working landscape elements. Each element of the mosaic influences other elements. Scientists from diverse disciplines are now recognizing that human history and policy are critically entwined with ecosystems and should be examined as social-ecological systems. Human institutions influencing resource use (e.g., accepted behavior, property concepts, decisionmaking, policy, rules, and governance) shape landscape patterns, processes, and perceptions, and subsequent human and societal responses (Brunckhorst et al. 2008). In practice, all human activities, including conservation actions and resource management, combine with ecological functions as dynamic processes that cross boundaries. Landscapes and institutions change together over time dynamically and responsively, and in doing so create meaningful contexts that local residents closely identify with and relate to as their place. This spatial context of place identity is also important to local people if policy-relevant representation is to forge sustainable resource use and novel conservation futures (Cheng et al. 2003). A revised conservation agenda that focuses on synthesis studies and opportunities beyond formal reserve networks, and on the rural communities of private citizens that will likely remain the landholders and guardians of the majority of biodiversity, provides several advantages: (a) a broader segment of society has ownership of and (placebased) commitment to the conservation enterprise; (b) both landscape and social connectivity within and among traditional reserve areas are increased; and (c) species and ecosystem protection are more spatially and temporally integrated with local social systems, increasing adaptive capacity and resilience. Past efforts to engage with private landholders and citizens have often met with limited success because of a lack of understanding of local communities of interest and the landscapes with which they identify. Conservation science and policy must begin meeting people in their own place and space. To do so requires an approach to delineating regional-landscape frameworks to integrate conservation outside formal protected areas with the humandominated, working landscape matrix. Landscapes Shaped by People and Place Institutions Require a New Conservation Agenda


IT affords me the greatest pleasure to place before the British medical profession the facts as to what has been called cinematic amputation. I feel this all the more because I am thoroughly convinced of the enormous advance which the conception of cinematization will bring about in the treatment of disabled men, and believe that all that concerns this new current of ideas, as well as tlle store of facts related to them, ought to be placed at the disposal of the world at large. i1n briefly reviewing the fundamental theories of plastic motors, and pointing out the vast field thus thrown open to the activity of orthopaedic surgeons and mechanical engineers through the practical application of these theories, I venture to express the hope that our efforts may prove welcome to all those who have hitherto had no opportunity of studying this important scientific innovation. Whilst in Italy the tireless work of propaganda undertaken by Dr. Giuliano Vanghetti, the original exponent of these theories, has led to their full discussion and close study and to many experiments, and whilst both German and Austrian scientists have been actively working to obtain the most practical application of these same theories, the medical literature of France, England, and America contains very few, if any, allusions to thie subject. In the space at my disposal I must content myself with outlining thle fundamental principles upon which the theory is based, pointing out, as briefly as possible, the various ways it can be put into actual practice, and making a short statement as to the metlhod of operation and the results. The possibility of utilizing the functional resources of the stump so as to convey movement to the artificial limb was an idea that came to Dr. Vanghetti first in 1896, at the time of Italy's second expedition into Abyssinia, when soldiers that had been taken prisoners by the native forces iunder the Negus were cruelly tortured and mutilated. From that time onwards Dr. Vanghetti wrote and published innumerable articles, wherein he developed his theory on what lhe had now named "cinematic amputation." In them he described very fully the origin of his idea and the various methods by which it could be practically applied. Unfortunately for the speedy acceptance of this most novel and useful idea, Dr. Vanghetti, though his originality, cleverness, and ability are indisputable, is not a surgeon, but a physician, and for this reason was unable to put his theory into practice. He was therefore forced to resign himself to endless delays before he succeeded in convincing surgeons of the great value and practical possibilities of his theory and obtaining their co-operation, which was indispensable to any adequate test. This was the principal reason why, prior to the war, the cases of cinematic amputations did not number more than twenty.


The article dwells upon the problem of Ukrainian speech culture formation of future jurists. The authors emphasize heuristics as a branch of rhetoric which is studied by law students who in this way obtain knowledge not only about persuasion, effective forms of speech influence on an audience, but also of the art of polemic, learn about dialogue speech in depth, form skills of running an argument. The art of polemic as a type of eloquence is very old. Heuristics as a kind of oratory was originated in the Ancient Greece. The art of running an argument is more complex kind of oratory than monologue eloquence. Heuristics as a rhetoric of the dialogue speech is represented in the following genres: discussion, polemic, dispute, debates, argument, etc. It is of a particular importance for future jurists since effective running of professional discussions leads to successful resolution of certain professional problems, prevents escalation of a conflict between parties, etc. This raises the question of a proper conduct of an argument which, first and foremost, relates to the psychology of running an argument (discussion, debates, dispute, etc.), especially speech culture of discussions, observance of speech etiquette. It is important to teach future jurists the culture of running arguments and use of non-offensive, diplomatic wording, as well as develop the skills to concisely express their opinion. While familiarizing the law students with the rules of conducting arguments, they need to be exposed to the criteria of self-evaluation of their speech skills. In the beginning of professional training, it is important to draw the future specialists' attention to difficulties which might arise in the process of the speech activity. Rhetoric of the dialogue speech has developed certain rules, techniques, and culture of heuristics which also have to be introduced to the future jurists. The article presents some of these aspects. These "golden rules of heuristics" should become the foundation to form the Ukrainian speech culture of a future specialist in the field of jurisprudence.


【Objective】To understand the dietary patterns and nutritional status of elderly cancer patients,and analyse influencing factors to provide for clinical nutrition therapy or dietary mission evidence. 【Methods】108 cases of elderly cancer patients were selected to use 24h dietary recall method for continuous patient 3d dietary survey,patient-general subjective global assessment( PG-SGA),body measurements and biochemical indicators for comprehensive evaluation of the patients. 【Results】Malnutrition rates was 87% by PG-SGA method. In terms of age, the comparison between severe malnutrition group and well-nourished group was statistically significant. Grouped according to PG-SGA,anthropometric nutritional status of different values,TSF,AMC,grip strength,BMI were statistically significant,TP,Alb,PA,Hb pairwise comparisons were statistically significant. For groups in different nutritional status,the energy,protein,carbohydrates,calcium,iron,zinc,vitamin A,vitamin B1,vitamin B2 pairwise comparisons were statistically significant. 【Conclusions】Elderly patients with tumors intaked less energy and nutrients,and should be involved in clinical nutrition staff with reasonable choice of nutrition interventions in the course of treatment.


After the W fiber/Zr - based amorphous matrix composites whose W fiber volumetric fraction is 60% are an-
nealed, the influence of annealing on the stress - strain response, dynamic fracture characteristic and fractographic pattern are
examined. The samples are 5mm in diameter with a length to diameter ratio of 1. They are tested by using Hopkinson
pressure bar, Scanning Electron Microscopy(SEM) and XRD. The experiment shows that, after being annealed, the amorphous
matrix is crystallized and the compressive strength of the material decreases obviously. The fracture mode of W fiber does not
change after annealing.


ABSTRACT The fabrication of polymer–metal hybrids in an additive process makes it possible to further improve the geometrical and material adaption in a multi-material design. In this work, PLA is fabricated through a fused filament fabrication process on AlSi10Mg structures manufactured by laser powder bed fusion. The mechanical connection is realised by form fit, for which different geometries are examined through tensile tests. Deep penetration of the PLA into the metallic structures is achieved by optimisation of the process parameters. The penetration depth is assessed through the use of micro-computed tomography. Finally, the interplay of mechanisms leading to a firm connection is discussed.


: Flexible reorganization of complex IoT (Internet-of-Things)-based sensor networks is crucial for the alignment of the sensor network's operational dynamics with that of the monitored external phenomenon. Software-Defined Networking (SDN), when supported by Cloud-level Network Virtualization (NV), offers a prospective avenue for a flexible sensor network that can re-orchestrate as the monitored process demands. In order to allow for seamless softwarization of the sensor network functional entities, this paper promotes function modularization and establishment of both virtual repositories of reusable software modules as well as requisite operational software. An architectural solution that is aligned with Industry 4.0's ideology is presented in this work. This along with the software-defined resources is deemed as a viable solution to re-orchestrate the physical sensor network. By means of example simulation scenarios, this paper highlights the utility of NV for flexible soft trialling of sensor network topological re-orchestration and highlighting the possible network downtime associated with that operation. The outcome offers potential for the utilization of the virtual environment and the dynamics retained within it to offer ground for pre-planning for best possible re-orchestration scenario that comply with adaptive interaction with the dynamics of the physical environment.


The Slufter is an estuary located in Texel's North Sea dunes and protects the hinterland from flooding from the North Sea. As the multi actor environment and the diversity of values and functions associated with the Slufter are recognized, this research focuses on developing an approach for the district water board to broaden the knowledge base and include stakeholder perspectives. The deepened system understanding is used in a knowledge intervention aimed at enhancing the long-term decision making on the inherently dynamic, coastal nature reserve. Although the knowledge intervention was possibly not as effective as it could have been, there are indications that synthesized system understanding can be useful in stakeholder settings. In particular, the information derived both from the model and the interviews with stakeholders provides an indication that a shared understanding of the ecological and social functions of the Slufter estuary can be enhanced by integrating a stakeholder approach and problem modeling. Also, practical implications for monitoring the inherently dynamic nature reserve. Further research should be aimed at development and verification the approach in order to have practical value for other projects within and beyond the district water board.


The cost of answering a query against an ontology is affected by at least three elements: the size of the ontology, the strategy followed to combine the data, and the order or plan in which data is processed. In the context of the Semantic Web, very large ontologies have been defined; therefore, techniques to identify efficient evaluation strategies are needed. We propose cost-based optimization techniques for SPARQL queries. In our approach, ontologies are modeled as a deductive database. The extensional database is comprised of meta-level predicates that represent the information explicitly modeled by the ontology; for each RDFS built-in vocabulary term, we define a meta-level predicate (e.g., subClassOf). The intensional database corresponds to the deductive rules that implement the semantics of the vocabulary terms (e.g., the transitive properties of the subClassOf term). Currently, we have developed the following techniques:


A total of 80 acute coronary syndrome patients were divided into 2 groups at random: GroupⅠ(40 cases) were given only conventional treatment,while azithromycin were added in GroupⅡ(40 cases) with a dosage of 0.5 g/d for 14 d. The frequency of hospitalization of the 2 groups in 3 months, 6 months,12 months were analyzed and compared. It was found azithromycin could reduce the bad events of acute coronary syndrome patients.


The invention discloses a rustproof chocolate insulating tank which comprises a stirrer, a tank body, a material inlet, an insulating chamber, a vacuum chamber, a power box and a material outlet, wherein the stirrer is erected in the tank body through a mounting plate; the material inlet is arranged at the top of the tank body, and the material outlet is arranged below the tank body; the vacuum chamber and the insulating chamber are respectively arranged above and below the tank body, and are separated through an isolating layer in the middle; and the power box is welded at one side of the surface of the tank body. Through the above way, the rustproof chocolate insulating tank disclosed by the invention is simple in structure, and is capable of preventing rust and guaranteeing processing temperature of the chocolate.