THE SEPARATION OF blood into its components so that the products of one donation might be used to treat three or more patients has become the standard of practice since plastic equipment was introduced into blood banking in the 1960s. In the first 20 to 25 years of component therapy, it was standard practice worldwide to harvest platelets by the platelet-rich plasma (PRP) method, and this method still is essentially the only one used in North America. In the United States, it is not widely recognized that a rapid change has occurred in Europe, to the use of a different approach, the buffy coat (BC) method. The purpose of this review is to trace the histories of these two methods and to assess their strengths and weaknesses.


Truncated hemoglobins build one of the three branches of the globin protein superfamily. They display a characteristic two‐on‐two α‐helical sandwich fold and are clustered into three groups (I, II and III) based on distinct structural features. Truncated hemoglobins are present in eubacteria, cyanobacteria, protozoa and plants. Here we present a structural, spectroscopic and molecular dynamics characterization of a group‐II truncated hemoglobin, encoded by the PSHAa0030 gene from Pseudoalteromonas haloplanktis TAC125 (Ph‐2/2HbO), a cold‐adapted Antarctic marine bacterium hosting one flavohemoglobin and three distinct truncated hemoglobins. The Ph‐2/2HbO aquo‐met crystal structure (at 2.21 Å resolution) shows typical features of group‐II truncated hemoglobins, namely the two‐on‐two α‐helical sandwich fold, a helix Φ preceding the proximal helix F, and a heme distal‐site hydrogen‐bonded network that includes water molecules and several distal‐site residues, including His(58)CD1. Analysis of Ph‐2/2HbO by electron paramagnetic resonance, resonance Raman and electronic absorption spectra, under varied solution conditions, shows that Ph‐2/2HbO can access diverse heme ligation states. Among these, detection of a low‐spin heme hexa‐coordinated species suggests that residue Tyr(42)B10 can undergo large conformational changes in order to act as the sixth heme‐Fe ligand. Altogether, the results show that Ph‐2/2HbO maintains the general structural features of group‐II truncated hemoglobins but displays enhanced conformational flexibility in the proximity of the heme cavity, a property probably related to the functional challenges, such as low temperature, high O2 concentration and low kinetic energy of molecules, experienced by organisms living in the Antarctic environment.


In modern pediatric oncology, one of the major questions being asked repeatedly across several disease groups is whether the use of less therapy could achieve the same cure rates. Answering this question has helped in reducing long-term toxicity, while simultaneously improving outcomes across several childhood cancers. In acute myeloid leukemia (AML), the United Kingdom Medical Research Council (MRC) group have answered this question through their consecutive trials [1–3]. The AML MRC 12 trial recruited patients over 8 years (1994–2002) and included both children and adults. An important question answered in this trial was whether reduction in number of courses of chemotherapy is safe. Investigators compared four versus five courses of chemotherapy in the favorable group and 5th course of chemotherapy versus hematopoietic stem cell transplantation (HSCT) for adults who did not have favorable cytogenetics [1]. For children, allogenic HSCT was restricted to standard and poor risk patients with a matched sibling donor. The outcomes of children included in this study were reported separately in which about 1/3rd (n1⁄4 135) of the eligible patients had dropped out of randomization and opted for either four or five courses, eventually only 270 (48%) of 564 registered patients were randomized [2]. This study was powered to detect a difference of 10% in outcomes between the two randomized arms and recruited enough patients for this purpose, but was not powered to detect a difference in outcomes for children alone. Finally, the study concluded no difference in outcome between the two arms and following this study four cycles of chemotherapy became the standard of care in AML across several cooperative groups [1,2]. More recently, the Children's Oncology Group (COG) reported their experience of reducing number of cycles of chemotherapy among low-risk group in childhood AML [4]. This was not a randomized trial, rather a comparison of two successive COG trials, AAML0531 and AAML1031, which used five and four courses of chemotherapy, respectively. Similar to the MRC 12 trial, the 5th course of chemotherapy in AAML0531 consisted of high dose cytarabine. The authors concluded that omission of 5th cycle was only feasible in a small subset of low-risk group AML who became minimal residual disease (MRD) negative at the end of induction-1 and had favorable cytogenetics/molecular features while similar patients but with a positive MRD and patients with uninformative cytogenetic/molecular features irrespective of MRD should receive five cycles of chemotherapy. Why was there a difference in choice in the number of cycles between the two trials? In the MRC 12 trial, the cumulative dose of cytarabine was 10.6 g/m versus 34.6 g/m for patients who received four versus five cycles of chemotherapy, respectively [1]. On the other hand, the COG's experience of reduction in cumulative cytarabine dose from 45.6 g/m to 21.6 g/m resulted in inferior outcomes even in the low-risk group AML [4]. Though the MRC 12 trial was a randomized study, it had a number of limitations. The study included patients with myelodysplastic syndrome, did not use MRD for response assessment, a subset of patients randomized to receive four cycles of chemotherapy subsequently also received HSCT and finally the study analyzed children and adults together [1,2]. While the MRC 12 trial proved non-inferiority of the arm which used 10.6 g/m of cytarabine, this cumulative dose is lower in comparison to contemporary protocols for childhood AML [2,4–7]. Several previous studies and meta-analysis have highlighted the importance of higher dose of cytarabine in the treatment of AML [8,9]. The Japanese group compared outcomes of non-core binding factor AML across two of their successive trials (AML-99 and AML-05) in children [5]. The AML-99 study administered six cycles of chemotherapy with a cumulative cytarabine dose of 51.4 g/m while the AML-05 study administered five cycles with a higher cumulative cytarabine dose of 68.4 g/m. HSCT was offered to patients with high-risk features in both studies and for intermediate-risk patients with match siblings in the AML 99 study. The authors concluded that repetitive courses of high-dose cytarabine which resulted in administering a higher cumulative dose


Widely utilized for numerous applications, wireless sensor networks have become a boon to the academia and industrial communities. However, the stringent energy constraints place a hurdle to the continuous functioning of the sensing devices. Clustering a network leads to a lesser number of nodes participating in active transmissions. Data aggregation reduces redundant packet sending. Given that transmission is the primary energy consuming activity for a sensor mote, this paper exploits the joint advantages of clustering and data aggregation in decreasing communication cost. A data centric analysis was performed to justify the use of data aggregation. Experimental results on a realistic platform with MICAz motes running TinyOS embedded system showed 22% energy savings and 13% overhead reduction, confirming the attractive advantages of data aggregation and clustering such as more efficient transmissions.


Applying the visible photopolymerisable resin as the carrier, the Arthrobacter ureafaciens cells were entrapped. The visible light irradiation did not affect effect on the survivability of the cells and the activity of xanthine dehydrogenase. For the degradation of hypoxanthine, the optimal temperature and pH were 35℃ and 8.0 respectively. The xanthine dehydrogenase of the immobilized cells was stable when the pH was in the range of 6.0—8.0 and at temperature below 40℃.The remained activity of the enzyme was 94.99% after ten batches of operation for degradation of hypoxanthine,and the average degradation rate of hypoxanthine was 99.19%.


A bit-oriented architecture for the digital finite impulse response (FIR) filter with adaptive coefficients is presented. Instead of using multipliers, the FIR operation is regarded as the summation of a larger number of operands. The architecture utilises two new word-level operand compressors, namely six-to-triple and six-to-double compressors. Both of these two compressors, multiple operands can be merged efficiently without long carry propagation. Using such compressors as the basic building blocks, a FIR filter can be implemented as a fast and regular structure that lends itself to automation. Experiments show that the FIR generator based on the proposed architecture could easily achieve a 44% power reduction as compared to the traditional high-speed transposed form.


Controlling ability of competitive aerobics body posture is the foundation. The control ability in body posture is very important in competitive aerobics. It's the key to score in a series of actions. So effective and special training plan must be made. This article aims at illustrating how athletes' perform each action and how they control their posture well in each action in order to offer some theoretical framework for aerobics trailing.


The invention discloses a refueling management system comprising a data server, a modem, a serial port server, and multiple refueling machines. The data server is configured to be connected to the serial port server through the modem to output or receive network data. The serial port server is configured to be connected to the multiple refueling machines to output control signals or receive state signals. The serial port server of the refueling management system completely replaces a multi-serial port card in function. The problems existing in the use of a multi-serial port server are solved. The embedded programmable serial port server is easier to use and more convenient to install.


People often face outcomes of important events that are beyond their personal control, such as waiting for an acceptance letter, job offer, or medical test results. We suggest that when wanting and uncertainty are high and personal control is lacking, people may be more likely to help others, as if they can encourage fate's favor by doing good deeds proactively. Four experiments support this karmic-investment hypothesis by showing that wanting an outcome over which one has little control increases donations of time and money (Experiments 1-2), but not participation in other rewarding activities (Experiment 1b). At a job fair, it causes job-seekers who feel the process is outside (vs. within) their control to make more generous pledges (Experiment 3). We further demonstrate that karmic investments increase one's optimism about a desired outcome (Experiment 4). Finally, we discuss the role of personal control and magical beliefs in this phenomenon. For so many important outcomes in life, there comes a point when, having done everything one can to make it happen, one must simply sit back and hope things work out. After all the résumé tweaking and hand shaking, the job seeker can only wait for the phone to ring. After all the test preparation and statement crafting, the high-school senior can only scan the mail for the dreaded thin envelope or the prized thick one. After controlling whatever can be controlled, we must eventually turn many outcomes over to " the universe " – some combination of controlling gods, other people's decisions, chance factors, and the fabled flapping of a butterfly's wings. We suggest that in these moments—when people face outcomes of important life events that are beyond their personal control—rather than waiting passively to learn their fate, people may act as if they can gain fate's favor by doing good deeds proactively. Specifically, we propose that the experience of awaiting an important, uncontrollable outcome increases the likelihood that people will do good deeds when confronted with the opportunity, as if they were " investing in karma. " For instance, the job seeker may be more likely to drop a few coins in the collection jar after interviewing, and the student may be more willing to offer a helping hand on days he finds himself obsessing about admissions. An alternative possibility is that individuals directed to focus on their own wants and needs may feel disadvantaged, more deserving, and therefore entitled …


performable opera translation, like a perA formable translation of a spoken drama, is made so that an audience not speaking the original language may have a full theatrical experience. Consequently, many of the problems faced by opera translators are the same as those faced by translators of spoken drama. In addition, of course, opera translators face the daunting problem of writing a translation singable to preexisting music (see, for instance, Apter 1989a, Apter 1989b, Herman and Apter 1991). But even a well-translated opera may not be accepted as drama by an audience, because of problems that usually do not arise with spoken drama. Some of these problems are inherent in the operatic genre, others are due to the training of the performers, and still others lie in the performance history of opera in English-speaking countries. In all cases, translators can take practical steps to at least mitigate, if not completely solve, these problems.


A 36-year-old female was admitted to our clinic with the complaints of inability to release a grasped object and easy fatigability since 11-12 years of age. In her past medical history, pre-, peri-, and postnatal periods were normal but she had had some difficulties in primary school. She had been married for 7 years, and had been given infertility treatment over the previous 3 to 4 years. About 40 days previously, she had given birth by Cesarean section.


A novel nonlinear model predictive control (NMPC) strategy for path tracking of autonomous vehicles with stable limit handling is proposed in this article. To improve the path tracking performance under complex driving maneuvers, a tire lateral force model, which treats road adhesion coefficient and vertical load as variable parameters, is discussed first. It has the advantage that the dynamics model can be applied under different driving conditions. In addition, the stability properties of the dynamics system with the front tire lateral force as the virtual control input are analyzed. The global asymptotical stability with zero input and local input-to-state stability with nonzero input of the dynamics system are proved respectively. To perform path tracking within the handling limits, both constraints of front tire lateral force and rear tire slip angle are included in the NMPC controller. The constraint of front tire lateral force is considered as peak limits related to load transfer and adhesion coefficient. And for the rear tire slip angle, a combining constraint scheme is proposed, where the indirect constraint is implemented by a penalty term that predicts the saturation of rear tire lateral force, while the direct constraint is implemented by a dead-zone exponential penalty function. The Continuation/Generalized Minimum Residual (C/GMRES) algorithm is applied to improve the computation efficiency of the NMPC. The performance of the controller is evaluated in simulations and hardware-in-the-loop (HIL) tests, and the results show that the controller is able to track the reference path with high precision in real-time.


Chiral amines are important components of 40-45% of small molecule pharmaceuticals and many other industrially important fine chemicals and agrochemicals. Recent advances in synthetic applications of ω-transaminases for the production of chiral amines are reviewed herein. Although a new pool of potential ω-transaminases is being continuously screened and characterized from various microbial strains, their industrial application is limited by factors such as disfavored reaction equilibrium, poor substrate scope and product inhibition. We present a closer look at recent developments in overcoming these challenges by various reaction engineering approaches. Furthermore, protein engineering techniques, which play a crucial role in improving the substrate scope of these biocatalysts and their operational stability, are also presented. Last, the incorporation of ω-transaminases in multi-enzymatic cascades, which significantly improves their synthetic applicability in the synthesis of complex chemical compounds, is detailed. This analysis of recent advances shows that ω-transaminases will continue to provide an efficient alternative to conventional catalysis for the synthesis of enantiomerically pure amines.


Interchanging information over networks is fast and easy to exchange data of great diversity.The development of XML brings new vitality on networks.In order to increase the reusability of network resources and extend the application of XML,this paper discusses how to organize and describe network resources by a case study and gives the method and process to describe and interchange resources.The method suits for describing various types of complex data by XML and brings great help to the applications of XML especially in e-commerce.


Analog and digital circuit ultimately need a voltage reference. The reference establishes a state point used by other subcircuits to generate predicable results. This reference point should not fluctuate significantly under various operating conditions such as moving power supply voltage, temperature variation, and transient loading events. A example a circuit amplification where reference are intrinsically require are linear regulators. A bandgap reference circuit for 0.35 µm CMOS technology operates in an essentially temperature independent manner and having low supply voltages. In the conventional bandgap circuit, the output voltage VREF is the sum of built-in voltage of the diode VBE and thermal voltage VT. Therefore VREF is about 1.2 V that is passing to regulator, which limits a low supply by linear regulator operation below 3.2 V.


It has been remarked in several previous works that the combination of center vortices and nexuses (a nexus is a monopole-like soliton whose world line mediates certain allowed changes of field strengths on vortex surfaces) carry topological charge quantized in units of 1/N for gauge group SU(N). These fractional charges arise from the interpretation of the standard topological charge integral as a sum of (integral) intersection numbers weighted by certain (fractional) traces. We show that without nexuses the sum of intersection numbers gives vanishing topological charge (since vortex surfaces are closed and compact). With nexuses living as world lines on vortices, the contributions to the total intersection number are weighted by different trace factors, and yield a picture of the total topological charge as a linking of a closed nexus world line with a vortex surface; this linking gives rise to a non-vanishing but integral topological charge. This reflects the standard 2\pi periodicity of the theta angle. We argue that the Witten-Veneziano relation, naively violating 2\pi periodicity, scales properly with N at large N without requiring 2\pi N periodicity. This reflects the underlying composition of localized fractional topological charge, which are in general widely separated. Some simple models are given of this behavior. Nexuses lead to non-standard vortex surfaces for all SU(N) and to surfaces which are not manifolds for N>2. We generalize previously-introduced nexuses to all SU(N) in terms of a set of fundamental nexuses, which can be distorted into a configuration resembling the 't Hooft-Polyakov monopole with no strings. The existence of localized but widely-separated fractional topological charges, adding to integers only on long distance scales, has implications for chiral symmetry breakdown.


This paper presents a new interpretation of Lu Xun's novels in the light of Bahkin and Foucault's theories of discourse analysis. The background of Lu Xun's novels generally centers in Luzheng and Weizhuang whose social discourses fall into six levels that reflect the conditions of the corresponding social classes and the relationship among them in the beginning of this century. The discussion focuses on three major discourse classes: the "aphasic" class who were deprived of their own discourse and forced to follow that of another class; the "soliloquy', class who had never learned their own discourse but were compelled to adopt an unusual or "hysterical" discourse; the "bilingual" class who were lost in the tension between the traditonal and an unborn new discourses. Lu Xun's contribution was that he expressed, through his analysis of the diverse discourses, his criticism of the traditional discourse discourse and his apprehension over the social situations for the 1911 revolution.


Abstract : The User-Interface Technology Branch at NCCOSC RDT&E Division has been conducting a series of studies to address the suitability of commercial off-the-shelf (COTS) graphic user-interface (GUI) methods for efficiency and performance in critical naval combat systems. This paper presents an advanced selection algorithm and method developed to increase user performance when masking selections on tactical displays. The method has also been applied with considerable success to a variety of cursor and pointing tasks. Typical GUIs allow user selection by: (1) moving a cursor with a pointing device such as a mouse, trackball, joystick, touchscreen, and (2) placing the cursor on the object. Examples of GUI objects are the buttons, icons, folders, scroll bars, etc. used in many personal computer and workstation applications. This paper presents an improved method of selection and the theoretical basis for the significant performance gains achieved with various input devices tested. The method is applicable to all GUI styles and displays sizes, and is particularly useful for selections on small screens such as notebook computers. Considering the amount of work-hours spent pointing and clicking across all styles of available graphic user-interfaces, the cost/benefit in applying this method to graphic user-interfaces is substantial, with the potential for increasing productivity across thousands of users and applications.


Large blocks of SKD-11 were treated by CVD-TiC coating process, TD coating process, TD coating process after vacuum heat treating, and vacuum heat treating. Amount of deformation was measured and compared to find the process which gives the least deformation. Wear tests were carried out for specimens treated by each process. Application of CVD-TiC and TD coating to the automotive press mold was studied.


Compost making is a method of recycling whereby organic waste is broken down to organic soil with the help of oxygen demanding microorganisms. There are different ways of making compost. Some require more labour and an exact procedure has to be followed; others neglect the precise procedure, which has advantages and disadvantages. Organic material, including toilet waste, can also be recovered to generate biogas before being composted. Biogas production allows recovery of the energy contained in liquid and solid household wastes, which can be put to an array of uses, such as cooking, electricity generation and heating or even for industrial use. This paper explains the factors which play a role in compost making.


Purpose To estimate the prevalence and risk factors associated with the primary angle-closure disease spectrum in participants of the Colombian Glaucoma Study. Methods A cross-sectional study in subjects older than 50 years with a diagnosis of diabetes mellitus or/and systemic hypertension was conducted in Colombia to estimate glaucoma prevalence. This study included 1749 patients and classified them using gonioscopy into either open-angle or primary angle-closure disease spectrum groups. The patients in the primary angle-closure disease spectrum group were then subdivided into the following categories: primary angle-closure suspect, primary angle-closure, and primary angle-closure glaucoma. A logistic regression model was carried out to identify factors related to the primary angle-closure disease spectrum, including age, sex, height, and refraction. Results The prevalence of primary angle-closure disease spectrum was 19.3% (338) (95% CI: 17.5–21.2). The prevalence of primary angle-closure suspect, primary angle-closure, and primary angle-closure glaucoma was 8.0% (140) (95% CI: 6.8–9.4), 10.1% (176) (95% CI: 8.7–11.6), and 1.2% (22) (95% CI: 0.8–1.9), respectively. In the multivariate analysis, advanced age (+80 years), female sex, and high hyperopia (p = 0.000, 0.021, and 0.001, respectively) were identified as independent factors related to the primary angle-closure disease spectrum. Conclusion A high prevalence of primary angle-closure disease spectrum was found in Colombian patients with a diagnosis of diabetes mellitus or/and systemic hypertension, especially primary angle-closure and primary angle-closure glaucoma. Age, female sex, and high hyperopia were identified as risk factors for the primary angle-closure disease spectrum.


Research on three-dimensional flow field in a tubular pumping system using numerical simulation based on the Reynolds time-averaged Navier-Stokes equations and the RNG k–e turbulent model. By using this method, the performance of pumping system such as head, shaft power and efficiency are predicted based on the calculation of different operating conditions in the discharge range from 20L/s to 35L/s at the same rotating speed. For verifying the accuracy and reliability of the calculation results, a tubular pumping system bedstand is designed for the permarmance test. The comparison of simulation results and the experiment data shown that the calculation performances close agreement with the experiment results in the high efficiency area, but in the condition of large discharge and low discharge, deviations were existed between the two results. Combining with the results of numerical simulation and experiment, which can provide more evidences for the hydraulic performances prediction and optimization design of pumping system.Copyright © 2013 by ASME


A project HSE management model named "One centre, Two basic principles" has been set up. and is expanded character is invesigated .


A alkalophilic strain, Bacillus licheniformis MH31 producing an alkaline protease was isolated from mine soil of Boryeong in Korea. Production of a high level of alkaline protease was achieved 42 h after incubation when the bacterium was grown at pH 9.0 and in Horikoshi medium supplemented with 0.5%(w/v) starch and 1%(w/v) skim milk as carbon and nitrogen source, respectively. The molecular weight of partially purified enzyme was estimated to be 30 kDa by SDS-PAGE and its optimum pH was pH 10. The enzyme showed optimum temperature at , and was stable up to after 1 h incubation. The protease was strongly inhibited by 1 mM of PMSF which was known well as strong inhibitor of serine proteases, but almost not inhibited by 5 mM of EDTA and 1,10-phenanthroline. When the protein hydrolysis products of 1% skim milk by partially purified protease was compared with available commercial proteases using HPLC analysis, most of hydrolysis products were detected below molecular weight of 10,000 and the hydrolysis ratio of purified enzyme was 24.8% lower than those(above 32%) of commercial proteases.


If commercial banks are permitted to underwriting corporate bond,it will be good for enriching the product range of corporate bonds,adapting to the continuing significant increase of corporate bonds issuance,and meeting the corporations' needs of financing and mergers and acquisitions.And this will also help to improve the problem that the structure of corporate bonds investors is single,to enhance the liquidity of corporate bonds in secondary market,to enlarge the exchange corporate bond market.Commercial banks have prominent advantages in customer resources,capital strength,means of service,marketing networks and some other aspects.And it will impact the security company's existing fixed business if commercial banks underwriting exchange corporate bonds.In addition,there are still some obstacles in the legal preparation for it.So we design some targeted policies based on these.


The design of a liquid solar collector that helps heat an indoor pool and household water is described. Collector design and specifications and installation of the collector are discussed.


In this paper, we investigate the contribution that visual perception affords to a robotic manipulation task in which a crumpled garment is flattened by eliminating visually detected wrinkles. In order to explore and validate visually guided clothing manipulation in a repeatable and controlled environment, we have developed a hand-eye interactive virtual robot manipulation system that incorporates a clothing simulator to close the effector-garment-visual sensing interaction loop. We present the technical details and compare the performance of two different methods for detecting, representing and interpreting wrinkles within clothing surfaces captured in high-resolution depth maps. The first method we present relies upon a clustering-based method for localizing and parametrizing wrinkles, while the second method adopts a more advanced geometry-based approach in which shape-topology analysis underpins the identification of the cloth configuration (i.e., maps wrinkles). Having interpreted the state of the cloth configuration by means of either of these methods, a heuristic-based flattening strategy is then executed to infer the appropriate forces, their directions and gripper contact locations that must be applied to the cloth in order to flatten the perceived wrinkles. A greedy approach, which attempts to flatten the largest detected wrinkle for each perception-iteration cycle, has been successfully adopted in this work. We present the results of our heuristic-based flattening methodology which relies upon clustering-based and geometry-based features respectively. Our experiments indicate that geometry-based features have the potential to provide a greater degree of clothing configuration understanding and, as a consequence, improve flattening performance. The results of experiments using a real robot (as opposed to simulated robot) also confirm our proposition that a more effective visual perception system can advance the performance of cloth manipulation.


The setting It's early on a Friday evening, and you're working as registrar in A&E. A 6 year old girl is rushed in as an emergency, complaining of headache; she is febrile with convincing nuchal rigidity. Your colleague performs a lumbar puncture, then you attempt to achieve intravenous access, and by the time the anaesthetic cream has cooked the microbiologist rings from the lab. The CSF contains 50 polymorphs, two red cells and is "teeming with Gram positive diplococci".


A 16-year-old girl presented with progressive exertional dyspnoea and palpitations of 3-year duration. The medical history revealed one episode of fever with migratory polyarthritis at the age of 7 years, but it was not further evaluated. On presentation, she was in sinus rhythm with a pulse rate of 88/min and blood pressure of 110/80 mm Hg. Examination revealed a tapping apical impulse in the fifth intercostal space, inside the mid-clavicular line, and a grade 3 parasternal heave. Auscultation revealed loud S1 with an opening snap. There was a mid-diastolic rumble at the apex, with presystolic accentuation. A pansystolic murmur of tricuspid regurgitation was audible. Basal crepitations and peripheral oedema were absent. Transthoracic echocardiography revealed severe rheumatic mitral stenosis (MS) (video 1) (peak and mean mitral valve …


Sustainable development of Ukraine is not possible without the functioning of a civilized land market.The Ukrainian government has formed a set of amendments to the Land Code and other laws and provides for the start of the land market in mid-2021. However, the mechanism for assessing land resources is not sufficiently developed and requires saturation of methodological and information support. The article proposes methods of land valuation and methods of determining its investment attractiveness for investors.The formation of the information base for the assessment of land resources is possible only by applying a retrospective method of analysis of data generated on Ukrainian lands in a market economy, due to the peculiarities of the interrupted evolutionary process. In the analysis of investment attractiveness of land assets, the main focus is on the possibilities of applying the method of standardization of indicators. Application of the offered methods will promote creation in Ukraine of the effective market of the earth with harmonious maintenance of interests of the Ukrainian people and investors. The purpose of this article is to study the methods of valuation of land assets of Ukraine to determine their investment attractiveness in the formation of the land market.


The adsorption of volatile aldehydes and ketones and other harmful substances from cigarette mainstream smoke by paper filter tips filled with activated carbon and chitosan were studied. The results showed that the release of carbonyl compounds in cigarette mainstream smoke can be efficiently decreased. Chitosan showed better adsorption of carbonyl compounds than activated carbon, but no obvious effect on tar and nicotine. However, the adsorption of carbonyl compounds by Chitosan is selective.


I began this book with a lot of anticipation as I was hoping to learn concepts that would be helpful for the care of adolescents with Fetal Alcohol Spectrum Disorder (a particular clinical interest). Although Multisystemic therapy (MST) is the official subtitle, this is in fact the book's main theme and narrative. This form of 'wrap-around' therapy comes from the Department of Psychiatry and Behavioral Sciences at the Medical University of South Carolina. All four authors are from this university.

The book sets the template for MST:

MST therapists are full time master's level, or highly competent, clinically skilled, bachelor's level, professionals assigned to the MST program solely.

MST therapists operate in teams of no fewer than two and no more than four therapists, plus a supervisor.

MST caseloads do not exceed six families per therapist, with the normal range being three or four "active" cases.

Expected duration of treatment is 3–5 months.

MST therapists are accessible at times that are convenient for their clients and, in times of crisis, very quickly.

The MST program will have a 24-hour-per-day, 7-day-per-week on-call system to provide coverage when MST therapists are on vacation or taking personal time.

Oh, that the Canadian Mental Health Care System could afford such luxury! At a time when many special needs case managers have a 100 to 150 client caseload, the thought of a maximum of 6 cases sounds a bit utopian. Nevertheless the MST program works and has performed well-funded outcome studies to evaluate the veracity and length of its effect.

The main clinical construct, as hypothesized source of the adolescent's serious emotional disturbance, was a deficit in their interactions. Unfortunately little clinical analysis appeared to be given to the additional mix of co-morbid issues, such as developmental and medical. The main emphasis was on psychiatric and substance use disorders.

The book appeared to be a bit too MST-centric and dismissed the history of family therapy interventions such as instrumental, strategic, systemic and narrative, with little ceremony. At the same time, family types were recognized in their method of dividing families into authoritative (high control, high warmth), authoritarian (high control, low warmth), permissive (high warmth, low control) and neglectful (low control, low warmth). The high control, high warmth family functioning was the apparent but unstated clinical goal.

The section on Crisis intervention and psychiatric emergencies was the most informative and practical, but one of the core elements was a child/adolescent psychiatrist available 24 hours a day, 7 days a week. This seemed only possible in large urban teaching hospital centres in Canada.

Overall the book is a good example of a labour-intensive community psychiatric intervention using well-developed protocols and training for a notoriously difficult patient population. It has been well evaluated and, as implemented and researched by the authors, shows positive effects on family relations and functioning, increased school attendance and less disability from adolescent psychiatric disorder and decreased substance abuse. As such, it is essential reading for administrators and clinicians working with this population in the community. Given the intensity and costs of the service, on going evaluations of the economics of service provision will remain an important component of evaluation and implementation of this program in community settings.


To ensure the reliability of an accessory it is subjected to a type test. These type tests, either conform national or international standards, comprise a multitude of electrical tests. An important part of this type tests is the heating cycle voltage test in which the thermomechanical behaviour of an electrically stressed accessory is tested. Based on the IEC 60502–4 this heating cycle voltage test takes 20 days after which some final tests have to be undertaken to conclude the electrical type test. Before starting these 20 days also some tests (voltage withstand and partial discharge) are performed as a rough check: is it sensible to start the 20 days test or not. However, during this heating cycle voltage test no additional measurements are to be performed, leaving us "blind". Normally speaking the thermomechanical and electrical stresses should not influence the behaviour of the accessory, but in case it does it will only appear at the end of the 20 days test (or earlier in case of a breakdown). This is not an imaginary situation because experience has shown that, depending on the type of accessory, on average 20. 50 % of all type tested accessories do not comply with the requirements [1]. In that case, possible crucial information remains undetected during these 20 days. To avoid this and give the manufacturer insight in the behaviour of the accessory, an on-line partial discharge (PD) detection and location system has been developed.


Accurate detection of arrhythmias is critical to patient well-being in clinical settings because the readings usually reflect acute and chronic cardiac problems. Because of variability between individuals and unavoidable noise, this is known to be a difficult problem even for human experts. This paper explores the use of deep neural networks for the task of classifying ECG recordings using recurrent and residual architectures. The proposed method tested on ECG dataset of 162 patients' readings that consist of three classes including normal sinus rhythm, cardiac arrhythmia and congestive heart failure. Results shows that proposed LSTM method having 4 hidden layers and optimization function as Adam gives maximum accuracy of 99.12% in comparison to other methods.


The recovery of organic dye molecules was achieved by using a colloidal magnetic seeding process under high-gradient magnetic separation. The recovery fraction of dye molecules was dependent on the adsorption capacity of the dye molecules. A magnetic colloid can recover a much greater amount of dye molecules than magnetite particles. The adsorption of orange II molecules was found to be an irreversible process, and orange II molecule could be more tightly adsorbed on a magnetic colloid than a magnetite particle surface.


ration of war.&dquo; Assured of American neutrality, Hitler could have moved against the United States when he was ready. The attack on Pearl Harbor, however, eliminated the isolationist opposition and so united the country internally as to give the President the strength he so urgently needed. &dquo;Consequently,&dquo; concludes Dr. Trefousse, &dquo;they (the Japanese) solved the President's dilemma and contributed greatly to final Axis defeat.&dquo;


In this work, we consider the evaluation of retrieval systems using incomplete relevance information. When the document collection is dynamic, as in the case of web retrieval, new documents are added to the collection over time. Hence, the relevance judgments become incomplete, and the judged relevant documents become a smaller random subset of the entire relevant document set. Also, in the case of large collections, identifying and judging all relevant documents becomes very expensive and the relevance judgments for large collections are also usually incomplete. Recently, Buckley and Voorhees showed that average precision and other current evaluation measures are not robust to incomplete relevance judgments, and they proposed a new measure for efficiently and effectively evaluating retrieval systems [3]. When complete relevance judgments are available, this new measure, bpref, is shown to rank systems in a manner similar to average precision. Furthermore, bpref is shown to be relatively stable even when the relevance judgments are highly incomplete or imperfect. Thus, bpref holds promise for the efficient and effective evaluation (ranking) of retrieval systems using large or dynamic document collections. Average precision is one of the most commonly used and cited system-oriented measures of retrieval effectiveness. It is known to be a stable [2] and highly informative measure [1]. If average precision is considered as the "gold standard" for evaluating retrieval effectiveness, an evaluation measure that is both highly correlated with average precision and also robust to incomplete and imperfect relevance judgments is desired. In this work, we describe a new evaluation measure that is both robust to incomplete relevance information and is also an estimate of average precision itself. Inferred average precision (infAP) estimates the full collection average precision from the pool subsample directly. Inferred average precision has the nice property that it is based on defining average precision as the outcome of a random experiment. In this work, we show the derivation of average precision as the expectation of this random experiment, and we further show how to estimate this expectation using the random pool subsample. Through the use of TREC data, we show that when relevance judgments are incomplete, inferred average precision


Energy storage systems (ESSs) allow improving the stability and efficiency of the electrical grids with a high penetration of renewable energy sources. Moreover, the use of Hybrid ESSs (HESSs) enables storage solutions with both high-energy and high-power densities, by combining different storage technologies such as diverse battery chemistries, ultracapacitors, or hydrogen fuel cells to name a few. In this article, an HESS-based multioutput multilevel (MOM) converter is presented. The proposed topology enables decoupled control of each ac converter voltage output. The internal switching states further allow the use of different storage units and high-quality multilevel voltage in each ac output. The mathematical model of the proposed topology and the defined operation region of the system, besides a model-predictive control strategy, are developed. Finally, simulation and experimental results validate the performance of the proposed topology.


A case study is made of an exceptionally heavy rainstorm that hit the northwestern coastal area of Kyushu, Japan, on 23 July 1982. The 5hr rainfall accumulation was as high as 412mm at the city of Nagasaki. The precipitation occurred along the warm front associated with a medium scale disturbance that developed along the Baiu front. The atmosphere in the pre-storm period was very moist through virtually the entire troposphere and its static stability was conditionally unstable with a lifted index of -1.5*, thus exhibiting characteristics more similar to the tropical atmosphere than the typical pre-storm environment over the midwestern United States in spring seasons. Prior to the development of heavy precipitation over the Nagasaki area, an intensive rainband was propagating with a speed of 40km hr-1 eastsoutheastward over northwestern Kyushu. Its structure is found to be different from the structure of typical tropical squall clusters in that the heaviest rainfalll occurred in the middle of the rainband without a well defined leading edge. A dramatic change occurred in the rainband when its southern tip reached the Nagasaki area; it stopped propagating and stayed there for the next 5hr. Its line structure changed to a blob structure at the meso-* scale (*100km). The timing of the precipitation development at Nagasaki coincided with the peak period of the incursion of very moist air associated with the southwesterly low-level jet. During the period of heavy precipitation, a new cloud cluster formed over the sea 300km west of Nagasaki. It kept developing and propagating eastward with a speed of 60km hr-1, and eventually merged with the rainstorm over Nagasaki. These observations strongly suggest that the Nagasaki rainstorm was trapped orographically. Several other heavy precipitation events are cited which also occurred in association with medium scale disturbances along the Baiu front and in which the precipitation developed over the coast areas upwind of the low-level


The household food security and nutritional status of children in the tea and non-tea producing households was investigated in this comparative study. This study focused on generating food consumption/purchase information from the farmers themselves, in order to achieve the set objectives. The objectives of this study were: to establish how much land was utilized for tea and food crop production; to determine gender involvement in income utilization; to assess nutritional status of children below five years in tea and non-tea producing households; to compare the nutritional status of children below five years in tea and non-tea producing households; to determine the food security status of tea and non-tea producing households and establish the relationship between nutritional status of children and the household food security in Ndia Division of Kirinyaga District. The study was carried out in Ndia Division of Kirinyaga District, and interview and observation guides were used in this study in order to collect data from a sample of 120 households comprising of 60 tea and 60 non-tea producing households. The data collected was summarized and analyzed by the use of the Statistical Package for Social Sciences (SPSS) programme. The qualitative data was organized into categories and then into themes where relationships were determined. Out of the 120 respondents, 116 (96.6%) had obtained education up to the secondary '0' level, while only 4 (3.4%) had achieved education beyond this level. The main source of income for the tea-producing households was sale of tea while the non-tea producing households did not have any specific source of income. Therefore most 37(30.8%), of the tea-producing respondents confessed regularity of their Income


OBJECTIVE: To determine the test condition and method in the microbial limit test of Bingpeng powder and to ensure a scientific test method and accurate test results. METHODS: The method verification was carried out in accordance with the microbial limit test recorded in the appendix of China Pharmacopeia ( 2005 edition, Volume I) . RESULTS: The neutralization method was determined as microbial limit test method for Bingpeng powder. CONCLUSION: This experiment provided scientific bases for the microbial limit test of Bingpeng powder, which is of great practical value for the production and test of this drug.


Obesity and type 2 diabetes are associated with impaired glucose homeostasis and blood lipid profiles. Further, a family history of diabetes (FH) increases the risk for development of insulin resistance. However, it is unclear whether a FH impairs glucose tolerance, blood glucose and lipid profiles in young, healthy, normoglycemic adults. PURPOSE: To investigate whether a FH impairs glucose tolerance and blood lipid profile in healthy, sedentary Hispanic males. METHODS: 22 sedentary, normoglycemic, Mexican American males (mean±SEM: age:23±0.56 yrs; BMI: 26.9±0.98 kg/m2) with/without FH participated in the study. Glucose tolerance was assessed by calculating glucose area under the curve (AUC) following an oral glucose tolerance test. Participants were fed a 5-day standardized diet (55/15/30% Carbohydrate/Protein/Fat) before testing. Serum was collected for analysis of blood glucose and lipid panels by a diagnostic center (Lab Corp, Burlington, NC). RESULTS: AUC was significantly greater in individuals with a FH compared to individuals without FH (FHvs FH+: 311.91±7.30 vs 355.35±11.91 AU; p=0.008). Fasting glucose (75.9±2.07 vs 79.1±2.85 mg/dL; p=0.40) and homeostatic model assessment of insulin resistance (HOMA-IR) (2.64±0.48 vs 1.81±0.19 AU; p=0.26) were not different between groups. There was no difference in fasting insulin between groups. Lastly, no differences in total cholesterol (p=0.18), triglycerides (p=0.28) or LDL cholesterol (p=0.24) were detected regardless of FH. CONCLUSION: Fasting glucose, insulin, insulin resistance (measured by HOMA-IR), and lipid profiles were not different between individuals with and without a FH. However, glucose AUC may be an early indicator of risk for developing insulin resistance in young adults with a family history of type 2 diabetes, despite an otherwise normal clinical health status.


The author criticizes a proposal in the Arizona Legislature to give tax credits to teachers for money they spend on school supplies. Instead, schools should provide more supplies or pay teachers more, the author says.


Whenever A = J. © A(\)p(d\) is a decomposable operator on a direct integral // = f. © H(\)p(d\) of Hilbert spaces and / is a function analytic on a neighborhood of o-(A), then we obtain that f{A(\)) is defined almost every- where and f(A)(X) = f(A(\)) almost everywhere. This relationship is used to study operators A, on a separable Hilbert space, for which some analytic func- tion A is a normal operator. Two main results are obtained. Let / be an ana- lytic function on a neighborhood of the spectrum of an operator A. If / (z) 4 0 for all z in the spectrum of A and if f(A) is a normal operator, then A is similar to a binormal operator. It is known that a binormal operator is unitarily equivalent to the direct sum of a normal and a two by two matrix of commuting normal opera- tors. As above if f(A) is normal and in addition, /(z) — £n has at most two roots counted to their multiplicity for each T in the spectrum of N, then A is a binor- mal operator. In this paper, all spaces are complex separable Hilbert spaces and all opera- tors on them are bounded. Various authors have investigated the structure of A whenever a particular function of A is normal. A. Brown (3) studied binormal oper- ators which included operators satisfying A = XI. He gave a structure theorem for binormal operators; these results have more recently been investigated in (2), and (15). J. Stampfli has shown that if A" is normal and A is invertible, then A is similar to a normal operator; subsequently, S. Foguel and C. Apostol have considerably generalized this result ((l), (lO), (12), (17)). In this paper, we generalize these results and show that it is possible to approach these and simi- lar problems through reduction theory of operators. Questions, concerning the struc- ture of operators, such as those investigated above will be reduced to questions about algebraic operators, which can then be handled with more elementary opera- tor theory methods. This approach seems new and essentially different from pre- vious works.


Abstract Throughout a year gizzards from 160 adult and juvenile rooks and 105 large young in rookeries were collected from Hawke's Bay. The main foods were invertebrates (especially Diptera larvae and Coleoptera adults) during the warmer months and walnuts and acorns in autumn and winter. When these foods were scarce cereals were taken, mainly from stubble. Other important food items were carrion, earthworms, peas, grass, and clover. Foods fed to young rooks were similar to those eaten by adults except that the young were fed more striped dung fly (Hybopygia varia) larvae (P < 0.025) and fewer blow fly (Calliphoridae) larvae (P < 0.025).


Abstract Croton malambo (Karst), is a small tree that grows in the northern Colombian coast and eastern Venezuela. Hydrodistillation (HD), microwave-assisted hydrodistillation (MWHD), simultaneous distillation-solvent extraction (SDE) and supercritical fluid (CO2) extraction (SFE), were employed to isolate volatile secondary metabolites from Colombian C. malambo (Karst) barks. The essential oil and extracts were analyzed by GC-MS. More than 20 individual components in the various extracts were identified. Methyl eugenol was the main component found in the HD and MWHD essential oils (63.5, 74.6 %), SDE and SFE extracts (67.1 and ca. 67.9 %<, respectively), followed by linalool (5.6, 3.4, 4.0 %), trans-β-caryophyllene (2.5, 2.6, 2.1 and 6.5 %) and trans-methyl isoeugenol (1.5, 1.9, 3.2 and 4.2 %). The oil obtained by HD presented a mean lethal concentration (LC50) against Artemia franciscana of 15.32 µg/mL and 2.20 µg/mL after 24 and 48 h exposition, respectively. These results show that C. malambo essential oil is an excellent source of methyl eugenol, but it is moderately cytotoxic. In addition, was evaluated the repellent activity of C. malambo essential oils against an important stored-product insect pest: Tribolium castaneum Herbst. These oils had high repellent effects on T. castaneum (92 % ± 3) at 0.2 µL/cm2 after 4 h of exposure.


Abstract of Making Their Way—Making Art and Making Money: The working lives of visual artists with disabilities Susan Agatha Maley People with disabilities have marked lower rates of employment than people without disabilities in both Australia and the United States, the countries chosen for this research inquiry. That this is the case decades after the introduction of anti-discrimination laws in these developed democratic countries highlights the continuum of constraints people with disabilities still experience in securing work. Some of these constraints include socially discriminatory attitudes and perceptions, the lack of available accommodations and adaptations in work settings (and the misconception that they will be onerous and expensive to implement), lack of accessible transportation, the unavailability of work within established job markets and the restrictions of vocational rehabilitation and disability employment programs' past focus on existing jobs in organisational settings. These constraints have a negative impact on the overall quality of life for many people with disabilities as employment is a key component to individual self-sufficiency and personal fulfilment and also crucial to inclusion in community and social settings. Among the notable initiatives to address these persistent inequities are research-informed projects focusing on self-employment as a viable alternative mode of employment to the established job market. Within the last decade, myriad research reports, model demonstration projects, and a US national research program, funded by the Office of Disability Employment Policy, have been demonstrating the success of self-employment in expanding self-determined income generation. Within this burgeoning and productive investigation on self-employment, one gap is that there has been little focused inquiry on creative work. Such a void is significant since the predominant work mode among visual artists is self-employment, albeit sometimes supplemented with other arts, and non-arts related work. This study addresses the lack of investigation of artists' modes of work by examining the working lives of practicing professional visual artists with a range of significant physical, sensory and neurological disabilities. There are a number of reasons for this research study's focus on the area of visual arts. Visual arts has been documented to be one of the largest groups among artistic disciplines in studies in both Australia and the US, as well as European countries. Within this sizable arts arena, there are established and emerging markets for sale of visual arts products. This discipline can also offer flexible work locations, hours and adaptations in art making. Thus, there may be numerous benefits to pursuing careers in the visual arts for creative people with disabilities. Yet, little is known about the lived work experience of practicing visual artists with disabilities and their career strategies. Thus, an exploration of visual artists with disabilities working in a range of mediums such as this research study can reveal new, and potentially useful, knowledge about their methods of art-making and marketing, adaptations in the design and execution of their work, their experiences of disability and the facilitators and obstacles they face when preparing for and pursuing their working lives as artists. This research study is based on the results of in-depth, face-to-face interviews of twenty-one visual artists, eleven in Australia and ten in the US, who used multiple artistic mediums. The conceptual lens for the analysis is intersectionality with an underlying critical realism foundation. These theories were used to explore the intersecting social positions of being a person with a disability and a practicing artist and the related interplay of agency and structure in shaping the careers of these artists. The main findings from this research focus on how the artists in this study made their way, made art and made money. These findings commence with an examination of the early shaping and continued sustaining influences in their artistic development and education. It continues with an exploration of the influence of their disability experiences on making art including their adaptive methods and conceptual process. The analysis continues with a focus on factors involving their means of making money, marketing and self-promotion methods and professional progressions. The findings conclude with an analysis of aids and obstacles these artists with disabilities experienced during interactions with a range of organisations including disability employment and vocational rehabilitation counselling and financial support agencies, arts educational institutions, art galleries and arts and disability agencies. Highlights of the findings are that the majority of the artists in the study earned their income from arts and arts related work, that they made active use of their own personal and collective agency to meet their artistic and professional goals and that their actions influenced structural change. They also positioned aspects of their social and personal identity to best suit their career progressions and some made artistic use of their conceptions of disability with innovative impact on social conceptions of disability. Implications of these findings are that artists experiencing disability developed strategic skills to negotiate difficult terrain while forging an income-producing arts practice. In addition, their creation of new options for themselves, and other artists with disabilities, has wider implications for improving equity for artists with disabilities.


. The collection of all sets of measure zero for a finitely additive, group-valued measure is studied and characterised from a combinatorial viewpoint.


In this study, we explore the characteristics with the IT project investments for improving the IT portfolio superiority. Our methodology is based on the computational modeling approach. The preliminary findings implicate that a firm could manage to improve on the selectivity, heterogeneity, and scalability in the IT project investments for portfolio selection.


In single-crystal Sm0.55Sr0.45MnO3, grown by the floating zone method with the cooling in oxygen, the spontaneous generation of voltage (SGV) has been observed. Its maximum, reached 60 μV, occurs at temperature region where simultaneous destruction of the CE-type antiferromagnetic order and charge order take place in some clusters. SGV maximum decreases on ∼ 40% by magnetic field 14.2 kOe. It is shown that SGV provokes of presence in sample of regions with different electrical charges.


Available computer models for estimating the exposure to substances from
multiple consumer products are not suited for this task. Consumers are
daily exposed to chemical substances from consumer products. The level
of this exposure has to be assessed to evaluate the consequences of
exposure to a substance for public health. Considering that a substance
may be contained in several consumer products (for instance, aromatic
substances, flame retardants and softeners), the contribution of these
products to the total exposure will have to be added up to determine the
aggregate exposure. Aggregate consumer (non-food) exposure is not
routinely evaluated in European assessment frameworks. This report
examines to what extent available computer models are suited for
evaluating aggregate exposure to consumer products. A method for
performing aggregate exposure assessment is also
described.


Alloy 925 were flooded in saturated H2S+10% NaCl aqueous solution for corrosion test,corrosion process characterization was recorded by potentiodynamic polarization curve and electrochemical impedance method.The results showed that corrosion potential decreased firstly and increased subsequently with test,corrosion rate of the overall trend of first increases and then decreases,combined EIS report that when the solution treatment was 960℃,the material owned better corrosion resistant.


I could not say much of the Mamalucs, of whom I know no author that has written in particular: neither did they deserve that any should. For they were a base sort of people, a Colluvies of slaves, the scum of all the East, who, having treacherously destroyed the Jobidae, their Masters, reigned in their stead; and bating that they finished the expulsion of the Western Christians out of the East (where they barbarously destroyed Tripoli, and Antioch, and several other Cities) they scarce did anything worthy to be recorded in History.


In this paper using distributed generation system in residential areas power quality is improved. To compensate harmonic resonance in residential areas, active and passive filters are used in distribution network. In the distribution generation (DG) system using photovoltaic interface inverter the harmonics were compensated. In general, increasing utilization of electronic devices in homes is a growing concern for utility companies due to harmonic distortions. The harmonic problem could be further complicated by the harmonic resonance introduced by other system components, such as the power factor correction (PFC) capacitors. Besides the degrading power quality, the harmonic current flow may interfere with the adjacent telephone lines. Compensating the harmonics in a residential system is difficult because of the dispersed nature of the residential loads. So, in this paper the power quality was improved reducing the load harmonics in residential distribution system. Due to installation of capacitor banks in the distribution network the harmonics resonance was worsen. So in order to reduce the harmonics distortion, active or passive filter are used.


In this paper we propose a version of the scatter search (SS) for tackling disjunctively constrained knapsack problems (DCKP). The DCKP is a special single constraint knapsack problem which contains specific additional constraints representing an independent set problem. The proposed approach applies the first level of SS using both the starting phase and the evolutionary one. Both phases are simulated using the five principal components of the scatter search, applied to an equivalent DCKP model re-enforced with two types of valid inequalities. The proposed algorithm is analyzed computationally on a set of problem instances of the literature which cannot be solved to proven optimality in a reasonable time. The obtained results are compared to the results provided by the Cplex solver; encouraging results have been obtained (19 new solution values out of 25 are obtained).


The notion that psychiatric disorders occur along dimensional continua rather than as categorical entities has long been debated. Research and clinical evidence have illustrated that a categorical diagnostic schema does not accurately reflect the full realms of clinical concerns in many patients, such as the presence of subthreshold anxiety or psychotic symptoms in individuals with major depressive disorder that cause or exacerbate impairment and distress (1,2). In some instances, clinicians are forced to diagnose two or three separate disorders, typically using the "not otherwise specified" label, in order to facilitate treatment for their patients (3).

In the absence of a fully dimensional diagnostic schema, the integration of dimensional assessments of psychiatric symptomatology may be clinically useful in providing valuable information for our current understanding of mental disorders and the issue of co-occurring symptoms and conditions (1). In addition, the integration of categorical diagnoses and dimensional assessments of psychiatric symptoms may also facilitate the identification and fine-tuning of psychiatric endophenotypes, as emphasized in the Research Domain Criteria, for the various mental disorders (4).

The DSM-5 Task Force and Work Groups developed and proposed the incorporation of dimensional measures – i.e., self-(i.e., adult and child/adolescent) and informant-report (i.e., parent/guardian) versions of the DSM-5 Cross-Cutting (CC) Symptom measures – to help address the issue of co-occurring symptoms across mental disorders (5–8). This paper discusses the benefits of the DSM-5 CC Symptom measures and identifies areas for further research and development.


EDITOR,—We were interested to read of the ballot of patients in Leicestershire over fundholding.1 We carried out a similar consultation process, which ended with a different result.

We are a small inner city practice, with 70% of our patients attracting a medium deprivation payment. Fundholding seemed to be the natural progression of the services we were already providing, and we believed that it would provide more choice for patients …


Charles University Faculty of Pharmacy in Hradec Králové Department of Organic and Bioorganic Chemistry Author: Jan Kubeš Supervisors: doc. PharmDr. Jaroslav Roh, PhD. PharmDr. Hana Jansová, PhD. Title of Diploma Thesis: Synthesis and in vitro evaluation of novel iron chelators based on salicylaldehyde isonicotinoyl hydrazone Iron ions (Fe) are required in many vital processes. However, this transition metal may also catalyze reactions which results in the formation of toxic reactive oxygen species (ROS), e.g. HaberWeiss reaction producing highly toxic hydroxyl radicals. Salicylaldehyde isonicotinoyl hydrazone (SIH) is a tridental chelator selectively forming complexes with Fe ions. As a result of its low molecular weight and good lipophilicity, SIH can be administered orally. It readily enters the cells, effectively chelates the intracellular Fe ions, and is therefore able to very efficiently inhibit the Fe dependent processes, such as production of ROS, but also the synthesis of some proteins and enzymes and the processes they regulate (e.g., cellular growth and proliferation). In this work we focused on the design, synthesis and in vitro evaluation of novel SIH analogues, in particular the thio analogue of SIH (thioSIH, A), analogues derived from (di)hydroxybenzophenone (B) and 2,6-dihydroxybenzaldehyde (C) (Figure 1). Figure 1. Structures of SIH and its analogues studied in this work. Sixteen analogues of SIH were successfully prepared and were evaluated for their ability to protect H9c2 cardiomyoblast cells against hydrogen peroxide-induced injury, their toxicity on the same cell line and their antiproliferative effects on HeLa (cervical cancer) cell line. Among the studied compounds, 2,6-dihydroxybenzaldehyde derivatives showed the most promising results.


The present invention relates to an anchor casting system for anchoring a marine drilling and landline the platform with the anchor falling craft, a rough structure of the anchor casting system is the deck, the chain action with the lifting path of the anchor acts capstan, wire rope drum , is installed under the deck comprises a cable winding drum which is provided on the rocker base and for mounting of a chain to a chain reciprocated by capstan datjul pipe. When lowering the anchoring yongjul After securing the anchor during each the platform chain of the platform to an already deployed anchoring yongjul to his deflection parts located always use the elevating unit and the anchoring yongjul lifting device for preventing slippage or separation of the anchoring yongjul.


This paper presents the design of a pneumatic robotic system to support the inspection of conduits according to the Electric Energy Company of the State of Rio Grande do Sul standard. Throughout the text is given an emphasis on mechanical solution developed, based on the movement of a caterpillar. Moreover, the pneumatic actuators are specified, the onboard electronics and thermal sensor used in the project. Results of the mechanical design and acquisition of images of the thermal camera are presented.


Relay-assisted communication techniques are important in modern wireless networks to extend coverage and save energy given a target performance. The maximization of these benefits requires proper methods to allocate power between source and relay nodes. In the presence of others cells with sources, destinations, and relays, the mutual interference can be a limiting factor which needs to be characterized. We propose a framework for analysis and design of relay-assisted communications which accounts for multichannel communications in each link, geometrical setting, interference, fading channel, power allocation, while being general with respect to coding and modulation techniques. We compare the performance with and without relay-assistance to quantify the benefits of relay and power allocation in terms of energy saving with respect to direct transmission.


Membrane distillation (MD) is a special evaporation process to produce fresh water from seawater or contaminated water using membranes. MD has advantages over other evaporation technologies such as multi-stage flash vaporization (MSF) and multi-effect distillation (MED) due to its relatively low energy requirements, allowing the use of solar energy as its heat source. Nevertheless, lack of membrane materials for MD process hinders its practical implementation for desalination and water treatment. In this study, membranes made of carbon nanotube (CNT) are presented for MD. Flat sheet hydrophobic membranes made of polyvinylidene fluoride (PVDF) were selected as supports for bucky-paper membranes, allowing formation of CNT bucky-paper without chemical reactions. Laboratory-scale systems were used to evaluate their potential and performance in direct contact MD. Water permeability and salt rejection were analyzed for each case. D.I water and synthetic feed water were used for the lab-scale tests. It was demonstrated that the physical immobilization of CNT on a hydrophobic membrane changed led to an increase in vapor permeability while improving salt rejection.


Abstract _________________________________________________________________ The aim of the research was to analyze the effect of the application of Active, Joyful and Effective Learning (AJEL) with bioedutainment strategy based on activity and learning outcomes of students in class X of MAN Kendal. Sampl e was collected by a purposive sampling technique with two experiment al classes, namely class X 4 and X 6 , whereas X 5 as control class. This study was a Quasi Experimental Desi gn with Non-Randomized Control Group Pretest-Posttest Design . Components of learning model that reflects the Active, Joyful and Effective Learning (AJEL) with bioedutainment strategy that used in this research was time token, outdoor learning, and gallery walk. Data were analyzed quantitatively. Tests using the t test showed the difference in the value of pretest-posttest experimental class is larger than the control class. The results of tests n-gain analysis of student learning outcomes obtained experimental class higher than the control class. Learning is effective because the classical > 75% of students achieving KKM, student activity> 75% and questionnaire responses of students >75% said that learning are fun and not boring. Abstrak ___________________________________________________________________ Penelitian ini bertujuan untuk menganalisis pengaruh penerapan Active, Joyful and Effective Learning (AJEL) berbasis bioedutainment terhadap aktivitas dan hasil belajar siswa kelas X MAN Kendal. Sampel penelitian diperoleh dengan teknik purposive sampling dengan dua kelas eksperimen yaitu kelas X4 dan X6, satu kelas kontrol X5. Penelitian ini merupakan penelitian Quasi Experimental Design, dengan pola Non-randomized Control Group Pretest-Posttest Design . Komponen model pembelajaran yang mencerminkan Active, Joyful and Effective Learning (AJEL) berbasis bioedutainment yang digunakan pada penelitian ini adalah time token, outdoor learning, dan gallery walk . Data dianalisis secara kuantitatif. Pengujian menggunakan uji t menunjukkan selisih nilai pretest-posttest kelas eksperimen lebih besar dari kelas kontrol. Hasil analisis uji n-gain hasil belajar siswa kelas eksperimen lebih tinggi daripada kelas kontrol. Pembelajaran dikatakan efektif karena secara klasikal >75% siswa mencapai KKM, aktivitas siswa >75% dan angket tanggapan siswa >75% menyatakan pembelajaran menyenangkan dan tidak membosankan.


The innovation and optimization for the traditional technology process of low-voltage power device were conducted. Based on original six-layer mask,the mask layers were reduced. The functions of protecting ring mask,working area mask and N+ area mask are were replaced by the contact hole mask. The electrical parameters of the device were simulated by designing the specific technology technological parameters,the feasibility of the technology was verified. The proposed parameters and design scheme are suitable for production and manufacture of all low-voltage MOSFETs.


The glottal pulse shape is usually estimated either by inverse‐filtering the speech wave or by taking a motion picture of the vocal cord vibration. We present a much simpler alternative based on the following idea: The effect of the vocal tract resonances on the glottal pulse is considerably reduced by speaking into a reflectionless uniform tube. If, in addition, the tract is held in a neutral position, the effect is almost entirely eliminated and the glottal pulse may be recorded by a microphone in the uniform tube. A number of examples are presented of glottal pulses recorded in this manner. Results of spectral analysis of these pulses are also presented.


Objective To investigate the clinical characteristics and influencing factors of Parkinson disease(PD) with depression(PDD),and to provide a better treatment for the disease.Methods Depressive states of 81 PD patients were evaluated with Zung Self-rating depressive scale(SDS) and Hamilton depression scale(HAMD).Meanwhile the seven factors scores of HAMD were recorded.Unified PD rating scale(UPDRS) and Hoehn-Yahr stages were used to evaluate the symptom severity of PD and the clinical type were decided:tremor type and rigidity type.According to SDS and HAMD,all patients were divided into two groups:PDD group and nondepressed PD(PDND) group.The differences of gender,age,course,UPDRS scores,Hoehn-Yahr stages and clinical type were compared between two groups.UPDRS and HAMD scores of PDD were recorded after 30 days in the patients who were administrated anti-Pakinson drugs accompanied with antidepressants or anti-Pakinson drugs alone.Results Fifty-two(64.2%) patients of 81 patients were PDD patients.Among these 52 patients,31(59.6%) patients were light depression,21(40.4%) patients were moderate and severe depression.The rate of depression in tremor type was 44.4% and that of rigidity type was 69.8%.UPDRS scores of PDD group were higher than those of PDND group.Anxiety/somatization,cognitive disturbance,blockage,sleep disorder and feeling of desire were the main characters of PDD.The patients who had higher UPDRS scores,higher Hoehn-Yahr stages were female,rigidity type had higher risk of attack of depression,and the difference was significant.UPDRS score and HAMD score of PDD patients who were given anti-Pakinson drugs accompanied with antidepressants decreased greatly than the patients who were given anti-Pakinson drugs only.Conclusion Depression is a very common psychological obstacle in PD patients,and majority is light depression.Female,rigidity type,severe PD patients have a higher risk of attack of depression.Anti-Parkinson drugs accompanied with antidepressants used to treat PDD decrease UPDRS and HAMD scores significantly and improve the clinical symptom compared to anti-Parkinson drugs only.


The term probiotic is derived from the Greek meaning ' for life ' and the fi rst formal description of a probiotic was provided by the Nobel laureate Metchnikoff in 1908, based on his observation that individuals who lived in a certain region of Bulgaria had a longer lifespan than their fellow citizens, a fact which he attributed to the regular ingestion of a fermented milk product [1]. The current accepted defi nition of a probiotic is a live organism that, when ingested in adequate amounts, exerts a health benefi t. In recent years many products have appeared on health food store and supermarket shelves which are labelled probiotic. Due to a widespread lack of uniform regulation extravagant claims for their effectiveness have proliferated. Fortunately, from a consumer perspective, times are changing and regulatory agencies around the world have begun to cast a forensic and skeptical eye on probiotics and their claims. What evidence, if any, is there to indicate that probiotics might have psychotropic actions or benefi t in patients with depression? Probiotics are a broad heterogeneous group of microbes and the most commonly used are lactic acid bacteria and non-pathogenic yeasts. Very few of the plethora of ' probiotic ' preparations marketed today fulfi l the defi nition of a probiotic [2]. They may not contain live organisms or have not been adequately tested to ensure that the organisms will survive in the conditions (e.g. room temperature) or for the length of time (days, weeks, or months) that is claimed. They may not confer a health benefi t because either they have never been tested in humans or because what studies have been performed have been grossly inadequate or even negative. In contrast to the relative paucity of high-quality clinical data, considerable information on the basic functions of probiotics and their interactions with the host has been generated from cutting edge basic science laboratories. Indeed, a series of studies have recently been published focusing on the impact of putative probiotics on the central nervous system and behaviour.


In general,Zhejiang rural welfare system is still a filled-type benefit.With the economic development of Zhejiang Province,some rural areas turn to the Pratt Whitney-type benefit and a basic system with supply,support,and help is formed gradually.Moreover,on social assistance pensions,health care and welfare services,series of activities including policy guidance,combined with the practical and dynamic adjustment are utilized.A situation of government,communities and farmers participation is formed in order to promote social welfare development in Zhejiang Province.


Variational Quantum optimization algorithms, such as the Variational Quantum Eigensolver (VQE) or the Quantum Approximate Optimization Algorithm (QAOA), are among the most studied quantum algorithms. In our work, we evaluate and improve an algorithm based on VQE, which uses exponentially fewer qubits compared to the QAOA. We highlight the numerical instabilities generated by encoding the problem into the variational ansatz and propose a classical optimization procedure to find the ground-state of the ansatz in less iterations with a better or similar objective. Furthermore, we compare classical optimizers for this variational ansatz on quadratic unconstrained binary optimization and graph partitioning problems.


In this paper,the forming principle and equipment refit of the sirofil spinning are intruduced.Compared with the same fineness of the ring spinning yarn,some experiments about the sirofil spinning performance have been done.The predominant performance of the sirofil spinning yarn is also discussed.


Burnside's theorem is one of the theorems derived from the concept of group action to find solutions to combinatorial problems that can not be solved by only using observations. This study aims to count the number of different orbits of every ten balls that form a regular triangle, if each ball of ten balls colored with one of three different colors. The research method is done by lowering the Burnside theorem through group action. Then present every ten balls in a mathematical notation. After that, present the group acts as an exchange position of the balls on the ten ball. Then create a simulated exchange position balls. The results obtained that the Burnside theorem can be proved by the action of the group. Burnside theorem can count the number of different orbits of the ten balls are colored by three different colors. A ten balls that form regular triangles are colored by three colors will result in 3 x 3654 ten different balls. Based on the results of the study concluded that the Burnside theorem can be used to calculate the number of ten different balls using a group action against every ten balls where each ball of ten balls colored with one of three different colors.


The emerging 5G New Radio (NR) networks will provide large improvements in mobile radio access in terms of peak data rates, latency, reliability and network capacity. One of the new technical elements compared to LTE-based networks is the support for millimeter-wave (mmW) frequencies, facilitating carrier bandwidths up to 400 MHz at the currently specified operating bands between 24–40 GHz. Such large bandwidths enable highly-accurate time-based measurements and hence ranging. Thus, in time-division duplexing (TDD) based networks, base-stations and possibly also user equipment can pursue high-accuracy radio sensing by observing the transmit signal reflections, assuming that the direct transmitter-receiver leakage or self-interference can be sufficiently suppressed. In this article, we address, analyze and demonstrate the prospects of OFDM-waveform based radio sensing in 5G NR base-stations with particular emphasis on the mmW use cases. First, basic target range and velocity estimation resolution analysis is provided for different carrier bandwidths and observation time windows, showing that close to centimeter-level ranging accuracy can basically be obtained. Then, specific emphasis is put on the analysis and suppression of the direct self-interference when executing the receiver simultaneously to transmitting. Finally, concrete RF measurements at 28 GHz operating band are provided and analyzed comprising self-interference cancellation and radar processing solutions. The obtained results demonstrate that direct self-interference cancellation can be successfully carried out, and that targets can be accurately sensed and tracked.


The Contempra is widely considered to be the first telephone designed and manufactured in Canada. Designed in 1967, Canada's centennial year, it was a conspicuous departure from prevailing conventions of North American telephone styling in both its conception and design. It was designated as an icon of Canadian modern design and became a symbol of Canada's identity as a modern nation at home and abroad. Its popularity in domestic and international markets set the stage for the transformation of its developer, Northern Electric, into a global telecommunication leader and Canada's most valuable corporation, eventually renamed Nortel Networks. The history of the Contempra's design and development offers an opportunity to consider how designed technological artefacts take on cultural and ideological meaning. Most accounts celebrate the Contempra as a distinctly Canadian design story, but do not elaborate on or question its 'Canadian-ness', and they are silent on the circumstances and events that culminated in the telephone's development. This article examines the historical events, ideological discourses, human relationships, design values and material constraints that set the stage for what can be best described as the Contempra telephone's performance of modern Canadian nationalism.


FAQs are the lists of common questions and answers on particular topics. Today one can find them in almost all web sites on the internet and they can be a great tool to give information to the users. Questions in FAQs are usually identified by the site administrators on the basis of the questions that are asked by their users. While such questions can respond to required information about a service, topic, or particular subject, they can not easily be distinguished from non-FAQ questions. This paper describes machine learning based parsing and question classification for FAQs. We demonstrate that questions for FAQs can be distinguished from other types of questions. Identification of specific features is the key to obtaining an accurate FAQ classifier. We propose a simple yet effective feature set including bag of words, lexical, syntactical, and semantic features. To evaluate our proposed methods, we gathered a large data set of FAQs in three different contexts, which were labeled by humans from real data. We showed that the SVM and Naive Bayes reach the accuracy of 80.3%, which is an outstanding result for the early stage research on FAQ classification. Experimental results show that the proposed approach can be a practical tool for question answering systems. To evaluate the accuracy of our classifier we have conducted an evaluation process and built the questionnaire. Therefore, we compared our classifier ranked questions with user rates and almost 81% similarity of the question ratings gives some confidence.


The whole notion of social work is dear to me. Doing something that benefits the common good seems like an eminently moral thing. However, what to do and how to use best one's potential is a puzzle. We flinch and duck when the term do-gooders is used but truth is, most of us want to do good things. But, what do we need to know and know how to accomplish good things?


The objectives of this work are to reliably measure the alkali-vapor (Na and K) concentration in a pressurized fluidized-bed combustion (PFBC) exhaust and to demonstrate a fixed granular-bed sorber for the control of alkali vapors from the actual PFBC exhaust. During this reporting period, Test Series No. 8 with the PFBC/alkali sorber unit was conducted to demonstrate the AASB technique and to quantify the level of alkali vapors in the PFBC exhaust. In Test Series No. 8, Beulah lignite (North Dakota) was combusted with Tymochtee dolomite at average bed temperatures ranging from 850 to 875/degree/C and a system pressure of 9.2 atm absolute. Beulah lignite has a low potassium but a very high sodium content (0.024 and 0.67 wt %, respectively, on a moisture-free basis); therefore, our effort was concentrated on the vapor-phase sodium for this test. 2 refs.


On the basis of the current studies,a boundary anti-aliasing algorithm is presented.This algorithm can implement the specific requirements of the cartographic visualization.Finally,two experiments are taken to test the effect and efficiency of the boundary anti-aliasing algorithm,which is well used in the cartographic visualization.


Most nutritional studies with seaweed meals or seaweed extracts have investigated low dietary inclusion rates (less than 10%) to establish their possible usefulness as functional (binder effect), nutritional, and nutraceutical (health protective effect) supplements in shrimp feeds. The optimum inclusion level varies depending on algae or consumer species. In many instances, the inclusion of algae in feed formulations has resulted in improved pellet quality (water stability, water holding capacity and texture), higher feed intake, improved feed efficiency, better growth performance and higher animal product quality (higher pigmentation, lower cholesterol content). Additionally, macroalgae contain some active compounds that can improve animal resistance against bacterial and virus diseases. Some seaweed species can be co-cultivated with shrimps, resulting in a sustainable alternative to reduce the need for artificial feed. In this paper the studies on the effects of seaweed inclusion in shrimp feeds or seaweed co-culture with shrimp will be reviewed.


Leiomyosarcoma of the duodenum is a L rare lesion. About 70 cases have been reported in the world literature (10–12). The findings on routine barium examinations are usually nonspecific. To our knowledge, no description has previously been published of the angiographic findings in duodenal leiomyosarcoma. A 55-year-old Caucasian male was admitted because of a one-year history of intermittent tarry stools. No abdominal masses were palpable. Laboratory studies, including liver function tests, were normal except for a hematocrit of 27 mm. Stool guaiacs were positive. A liver scan was considered negative. An upper gastrointestinal series (Fig. 1) and arteriography, including selective celiac and superior mesenteric studies (Fig. 2), were performed. Operation revealed an 8-cm nodular, highly vascular mass arising from the posterior wall of the second portion of the duodenum and involving the head of the pancreas. A Whipple procedure was performed. Pathologic examination documented a moderately well differentia...


The article analyses M.N. Katkov's pedagogical views and their connection with his philosophical attitudes is discovered. The sociopolitical arguments for classical education and his suggestion for reforming the University statutes are considered. The paradox of these ideas and their positive and negative aspects are shown.


Magnetic properties and magnetocaloric effect (MCE) of HoFeSi compound have been studied systematically. HoFeSi compound undergoes two successive magnetic phase transitions with the variation of temperature: a paramagnetic to ferromagnetic (FM) transition around TC =29 K followed by an FM to antiferromagnetic (AFM) or ferrimagnetic (FIM) transition at Tt = 20 K. The field dependence of magnetization reveals that a field-induced AFM/FIM-FM metamagnetic transition occurs below Tt with the increase in magnetic field. For a relatively low field change of 2 T, successive inverse and normal MCEs are observed and the maximum ΔSM values reach as high as 5.6 and 7.1 J/kg K around Tt and TC, respectively. This feature of successive inverse and normal MCEs in HoFeSi are suggested to be applied in some magnetic refrigerators with special designs and functions.


Abstract : The Quality Improvement System for Procurement Instruments (QISPI) as presented in this report has considerable potential as a tool for procurement managers to control the quality of their instruments. Document quality measurement and control begins with a quality indicator (QI) calculation based upon the number and type of instrument deficiencies per page. Standard control charts are used to determine document acceptability and track quality levels at the commodity commands. The QI values from each command are adjusted at the HQ DARCOM level to reflect review board proficiency and sampling percentages which results in the final performance indicator (PI) calculation for all of DARCOM. System test results from tests conducted at selected major procurement activities of DARCOM will be carefully evaluated during and after the test to confirm the appropriateness and utility of the system and to make any necessary improvements. Recommendations regarding QISPI implementation are postponed until the tests are completed. (Author)


Deteriorating education level, poor institutional performance and low performing students under stress and uncertainty was the problem area covered by research work. School level education is the most important and it sets foundations for further education. Most of the students quit just after primary level education. A lot of private school teachers leave their teaching jobs every year and are working as medical representatives, delivery persons and in other trades and professions. It is quite important to understand why low-fee private school teachers leave their jobs resulting in high staff turn over. It is crucial to assess factors that cause job dissatisfaction among private school teachers.


This paper presents the development of a methodology for laser interferometry based pose measurement of a three degree of freedom (DOF) planar nanopositioning stage, and its use for tracking control over a large workspace. The proposed methodology employs a miniature pure rotation scanner mounted atop the stage's end effector to provide compensation for any sensor misalignment introduced through motion of the yaw axis, thereby reducing the impact of geometric errors. A feedforward-feedback compound controller is established for both the misalignment compensation and tracking aspects of operation, and experimentation is performed which demonstrates high precision positioning. Sensor positioning considerations are shown to have a crucial impact on tracking performance.


The theory of nonlinear oscillations should provide a useful tool for studying both forced and self-generated oscillations in continuous crystallizers. The application of the theory is described in this paper for the case of self-generated oscillations in a MSMPR (mixed-suspension, mixed product removal) isothermal crystallizer. Although the process parameters do not correspond to typical industrial conditions, the results indicate that for the Class I system studied higher yields sometimes can be obtained from the periodic process than the steady state design. Thus, there may be some situations where oscillatory operation is advantageous.


Xanthomonas oryzae pv. oryzae (Xoo), the causal agent of rice bacterial blight is a common reason for severe economic yield losses in rice. Plant response to one type of stress can be affected by simultaneous exposure to a second stress, for example when abiotic and biotic stresses occur together. In this study, two genotypically contrasting genotypes were challenged inoculated under different drought levels (based on field capacity). In compatible interaction, the susceptible genotype TN-1 showed great response to infection and expressed highly under all drought conditions. Symptoms appeared firstly at 6 DPI (day post inoculation) and gradually increased up to 14 DPI. Maximum lesion length was observed at drought level of 60% field capacity (12.02 cm) and minimum (5 cm) was recorded at no drought condition (100% field capacity) on 14 DPI. Same in case of bacterial multiplication rate, maximum CFUs (colony forming units) were recorded at drought level of 60% field capacity and minimum were recorded at no drought condition. In incompatible reaction, BPT5204 genotype showed no symptoms, on the contrary bacteria multipled in the host and observed maximum numbers of colonies at drought level of 60% field capacity. This study has shown the direct responses of the two contrasting genotypes under different drought stress.


Calculations are presented for the exclusive pion radiative capture reaction from complex nuclei [ital A]([pi],[gamma][ital N])[ital B] in the framework of the nonlocal distorted wave impulse approximation. Our results are found to be in reasonable agreement with a recent TRIUMF experiment [sup 16]O([pi][sup +],[gamma][ital p])[sup 15]O. Since pion radiative capture is related to pion photoproduction via time reversal invariance, the findings reported here are at variance with the recent BATES experiment [sup 16]O([gamma],[pi][sup [minus]][ital p])[sup 15]O.


A systematic study to determine the effect of dose and dose rate on implanting oxygen at 80 and 160 keV is reported. Samples were produced by implanting oxygen into p-type Si


The phosphoryl absorption band in the infrared spectra of organic phosphorus compounds appears in the region 1320–1150 cm−1 as a doublet. Goldenson has reported that the phosphoryl doublet may be due to the hydrogen bond formed with impurities that cannot be removed by ordinary purification methods. However, as the relative-intensity ratio of the doublet changes in different solvents, the phosphoryl double probably results from more than inter-molecular hydrogen bonding. Consequently, other fundamental causes must be considered.


Image classification using deep learning has been widely implemented, primarily in medical imaging. However, features and focus regions are extracted by the network, becomes a black box mystery in the feature extraction layer during network training, unlike conventional feature extraction approaches, where various methods can extract image features. Regardless, traditional image feature extraction is laborious to find the most suitable algorithm. It takes time to meet the significant image features before classification and final image localisation, especially for the microscopic images. Therefore, a method to localise the region of interest (ROI) in vitro of the colony-formation unit (CFU) of hematopoietic stem/progenitor cell (HSPC) using gradCAM through deep learning, approaches have been proposed. This work comprises three main phases: CFU data preparation, convolutional neural network (CNN) pre-trained networks and localisation of the ROI. The proposed method has successfully localised the ROI of the CFU HSPC using gradCAM through a deep neural network with 87.5% sensitivity performed by DarkNet19. The finding of this work can be used as a baseline for future CFU HSPC classification that focuses on the CFU region.