Our aim was to reduce heterogeneity and microbiological contamination risk on small ruminant semen cryopreservation by replacement of fresh egg yolk by pasteurized powdered egg yolk, assessing simultaneously the effect of the donor age (1 year v. 2 years old) on sperm head morphometry of fresh and thawed sperm. Briefly, fresh ejaculates from 8 rams and from 8 bucks were collected in autumn during 2 consecutive years. Immediately after collection, ejaculates from each species were mixed in equal quantities, and pooled semen was centrifuged twice (600 g for 10 min). Then the pellet was split into 2 aliquots and resuspended in an extender containing 15% (v/v) of fresh or powdered egg yolk supplemented with 5% glycerol in a Tris-based medium. Afterward, sperm samples were refrigerated at 5°C for 4 h before being frozen in nitrogen liquid vapours. Buck and ram sperm-head morphometry was analysed by computer-assisted sperm analysis (ISAS®) on fresh and thawed sperm previously stained with Diff Quick®, and the data were analysed using ANOVA (mean ± s.e., n = 6). From ram sperm studies, no differences were found between fresh and post-thaw sperm, neither between egg yolk-based extenders or donor ages, showing the following mean values of head length (8.4 ± 0.0 μm), width (4.9 ± 0.0 μm), area (34.2 ± 0.1 μm2), perimeter (23.4 ± 0.1 μm), ellipticity (1.7 ± 0.0), elongation (0.2 ± 0.0), rugosity (0.8 ± 0.0), and regularity (0.9 ± 0.0). Likewise buck semen did not show significant differences on sperm-head dimensions after cryopreservation, only on head-shape parameters as ellipticity, elongation, and regularity between fresh and thawed sperm from 2-year-old donors, independently of egg yolk used as cryoprotectant. However, the age of the buck had a significant effect on all assessed morphometric parameters in fresh and thawed sperms, except regularity (Table 1). Our results suggest that, from a morphometric point of view, the powdered egg yolk can be used satisfactory on small ruminant sperm cryopreservation, but in goats, the head changes due to the donor age should be considered. Table 1.Effect of fresh v. powdered egg yolk (EY) in the extender and donor age on fresh and thawed buck-sperm morphometry Research supported by INIA (RZ2009–00008–00–00), Generalitat de Catalunya (2009SGR0621 and CUR-DIUE), and FSE and Fundacion Carolina.


This book represents a comprehensive collection of state-of-the-art ideas on the potentials of interactive television (iTV), which is, simply speaking, television broadcasting whereby a feedback loop enables instant (or even slightly delayed) two-way communication between the television broadcaster and the audience. The book initially affirms the magic appeal of interactivity for both scholarly thinking and media practice. In fact, starting with the book's preface, one is reminded of antecedent critical pointers about TV's role in contemporary society and discussions around its legitimacy as a social institution. This historical approach prepares us well for the discussions that surround the current pledge for a panacea of today's television broadcasting illnesses brought about by interactivity. Indeed, as the book's German title suggests, there is understandable scepticism as to the magic powers repeatedly ascribed to the interactive future of television broadcasting, perhaps because the promises are rather elusive. Let us cite Tracy Swedlow, founder and editor-in-chief of the U.S.-based Interactive TV Today, a widely read news source, who had surmised the medium's promising future already in 2000 as follows:


The rise in demand for specialized medical services in the U.S. has been recognized as one of the contributors to increased health care costs. Nuclear medicine is a specialized service that uses relatively new technologies and radiopharmaceuticals with a short half-life for diagnosis and treatment of diseases. Nuclear medicine procedures are multi-step and have to be performed under restrictive time constraints. Consequently, managing patients in nuclear medicine clinics is a challenging problem that has received little research attention. In this paper, we derive algorithms for scheduling nuclear medicine patients and resources. We validate our algorithms using simulation of an actual nuclear medicine clinic based on historical data and compare the performance of our algorithms with the methods currently used in the clinic. The results we obtain provide useful insights into managing patients and resources in nuclear medicine clinics. For example, results show that patient throughput can be increased when some clinic resources are reserved to exclusively serve specific procedures on those days when higher demand is expected.


Relationship between Parity and Diabetes Mellitus and Interaction with Breastfeeding Period among Postmenopausal Women Seonah Lee, Byongho Tchoe, Sae Young Jae, Sangshin Park Graduate Student, Graduate School of Urban Public Health, University of Seoul, Seoul; Professor, Graduate School of Urban Public Health, University of Seoul, Seoul; Researcher, Institutional Review Board, Seoul Medical Center, Seoul, Korea


Abstract Increased emphasis in the provision of early intervention programmes with families of biologically impaired or at‐risk infants, in recent years, has produced a wide variety of such services based upon various conceptual and empirical analyses of early development. The impact of these early interventions has been investigated quite extensively since the mid‐sixties, particularly regarding positive effects upon intellectual development. A synthesis of recent research regarding mother‐child interaction patterns and the influence of these social interactions upon cognitive, linguistic, and social development has resulted in a shifting emphasis in early interventions from the parent‐as‐teacher model to a parent‐infant interaction model. In concert with this shifting emphasis, interactional models of intervention are considered and described which provide the basis for identifying specific intervention strategies related to parent‐child interaction dynamics. These strategies provide the basis for progr...


Sexual behavior carried out is not in place, so it will violate a norm that is living in the community. According to the Criminal Code it is referred to as a crime. But in everyday practice often the occurrence of sexual behavior is called sexual harassment. This research is about tackling sexual behavior in tourism areas where researchers themselves find various forms of deviant sexual behaviors such as courtship at a place of tourism, romance in a place of tourism. Not only do sexual forms vary in their forms, they can be in the form of sexual violence, sexual abuse, forced marriage and forced abortion. From the results the researchers did about free sex, where the perpetrators were mostly teenagers without marriage ties, they were in the background of I by several factors both from internal and external factors.


This paper describes plastic foam processing for the manufacture of LLDPE foams in rotomolding. In order to better understand the mechanisms of foaming, a fundamental study on the foaming process in rotomolding has been conducted. First, the decomposition behavior of the chemical blowing agents was studied by a thermogravimetric analyzer (TGA). The zero-shear viscosity of LLDPEs was measured using a rotational stress rheometer. Also, an optical microscope with a hot stage was used to study cell nucleation, growth, coalescence, and coarsening in LLDPE melts, which provide an improved understanding of the foaming dynamics with a chemical blowing agent in rotational molding. Finally, the actual foaming behavior in rotomolding has also been studied. The experimental results indicate that the amount of blowing agent, the heating time, and the processing temperature play important roles in determining the cell morphology in rotational foam molding.


Exposure to radioactivity is not a new phenomenon: Jewelry workers painting luminous dials on watches in the 1920s were exposed to radium, a naturally occurring radioactive element, until its dangers were identified; in recent decades, homeowners have worried about radon, a naturally occurring radioactive gas that can adversely affect both their health and the resale value of their homes. Today, we must worry as well about the enormous quantities of anthropogenic radioactive materials that have accumulated as waste in this country and worldwide since the 1940s, largely because of the nuclear weapons programs and nuclear power plants. Some of the anthropogenic material is still valuable—for example, as fuel for nuclear reactors. Vast amounts of it, however, consist of waste. Radioactive waste, by definition, is unneeded material that contains unstable elements that decay by emitting alpha, beta or gamma emissions. This article describes the sources of this waste, the types of waste that are of concern and ...


A Model of Dopamine and Uncertainty Using Temporal Difference Angela J. Thurnham* (email@example.com), D. John Done** (email@example.com), Neil Davey* (email@example.com), Ray J. Frank* (email@example.com) School of Computer Science,* School of Psychology, **University of Hertfordshire, College Lane, Hatfield, Hertfordshire. AL10 9AB United Kingdom from their electrophysiological characteristics, during a delay paradigm of classical conditioning to receive a fixed juice reward, while manipulating the probability of receipt of the reward. Two related but distinct parameters of reward were identified from the activation produced, after learning had taken place: (i) A phasic burst of activity, or reward prediction error, at the time of the expected reward, whose magnitude increased as probability decreased; and (ii) a new slower, sustained activity, above baseline, related to motivationally relevant stimuli, which developed with increasing levels of uncertainty, and varied with reward magnitude. Both effects were found to occur independently within a single population of dopamine neurons. Abstract Does dopamine code for uncertainty (Fiorillo, Tobler & Schultz, 2003; 2005) or is the sustained activation recorded from dopamine neurons a result of Temporal Difference (TD) backpropagating errors (Niv, Duff & Dayan, 2005)? An answer to this question could result in a better understanding of the nature of dopamine signaling, with implications for cognitive disorders, like Schizophrenia. A computer simulation of uncertainty incorporating TD Learning successfully modelled a Reinforcement Learning paradigm and the detailed effects demonstrated in single dopamine neuron recordings by Fiorillo et al. This alternate model provides further evidence that the sustained increase seen in dopamine firing, during uncertainty, is a result of averaging firing from dopamine neurons across trials, and is not normally found within individual trials, supporting the claims of Niv and colleagues. Keywords: Dopamine; Uncertainty; Single Cell Recordings; Temporal Difference; Computer Simulation. Dopamine and Uncertainty Current theories of the effects of dopamine on behaviour focus on the role of dopamine in Reinforcement Learning, where organisms learn to organise their behaviour under the influence of goals, and expected future reward is believed to drive action selection (McClure, Daw & Montague, 2003; Montague, Dayan & Sejnowski, 1996; Schultz, Dayan & Montague, 1997; Suri & Schultz, 1999). Single cell recordings of dopamine neurons have identified a phasic dopamine burst of activity which is posited to be a reward prediction error (Schultz, 1998; Waelti, Dickinson & Schultz, 2001) and Temporal Difference (TD) Learning (Sutton, 1988; Sutton & Barto, 1998), a form of Reinforcement Learning, provides an explicit method of modelling and quantifying this error (Hollerman & Schultz, 1998; Schultz et al., 1997). It is likely that disruption to the dopamine system gives rise to an abnormality in information processing by dopamine and some of the symptoms currently associated with schizophrenia, particularly psychosis and deficits in working memory. It has been posited that dopamine also codes for uncertainty (Fiorillo, Tobler & Schultz, 2003), as under conditions of maximum uncertainty, observations of single cell recordings have shown a sustained increase in activity from presentation of a conditioned stimulus (CS) to the expected time of a reward. They recorded the activity of neurons in two primates, identified as dopamine neurons Figure 1: Sustained activation of dopamine neurons with uncertainty taken from Fiorillo et al. (2003) (A) Rasters and histograms of single cell activity (B) Population histograms With uncertainty, the sustained activation began on presentation of a CS and increased in strength until a reward was due, at which point the activation ceased (Figure 1B, where P = 0.25, 0.5 and 0.75). This activation was greatest


Abstract In this paper, we introduce a novel 60Co-ray-irradiation-based one-step synthesis method of Pt-reduced graphene oxide composites (Pt-RGO) in acid aqueous solution. The compositional distribution of the particles in the samples was characterized by transmission electron microscopy. The structure and composition of the nanocomposite has been determined with a scanning electron microscope (SEM) equipped with an energy dispersion X-ray (EDS) analyzer. Surface enhanced Raman scattering (SERS) of graphene deposited by the Pt nanoparticles were investigated with the 514.5 nm excitation. It was found that small-sized and highly-dispersed Pt nanoparticles could easily grow on the RGO surface under acidic conditions. In addition, the obtained homogeneous dispersions exhibit long-term stability, which will facilitate the production of homogeneous composites.


Purpose: The purpose of this study was to evaluate the effect of focal double-frequency yttrium-aluminum-garnet (YAG) laser therapy in patients with central serous chorioretinopathy (CSCR) resistant to intravitreal bevacizumab (IVB) injections. Methods: This is a retrospective analysis of 16 eyes of 16 patients with CSCR of >3 months duration who had been previously treated with multiple injections of bevacizumab (average 2.7) with no improvement in best-corrected visual acuity (BCVA). All patients had been treated using multiple spots of focal double-frequency YAG laser over areas of focal and diffuse leak. Spectral domain-optical coherence tomography (SD-OCT) was done a day before laser treatment and at 1, 3, and 6 months after. Fluorescein angiography was done for all patients to locate leakage site before laser treatment. Reduction in subretinal fluid height on SD-OCT was used to measure the response to treatment. Results: Mean age of patients was 37.6 ± 3.9 years. The baseline BCVA was improved significantly (P < 0.001) from 0.39 ± 0.45 logarithm of the minimum angle of resolution (log MAR) to 0.11 ± 0.43, 0.10 ± 0.44, and 0.09 ± 0.45 (log MAR) at 1, 3, and 6 months posttreatment, respectively. The baseline OCT mean central macular thickness decreased significantly (P < 0.001) from 554 ± 45 μm to 285 ± 38 μm, 279 ± 34 μm, 275 ± 33 μm at 1, 3, and 6 months posttreatment, respectively. Conclusion: Focal double-frequency YAG laser therapy improved the BCVA and reduced neurosensory detachment in patients with CSCR resistant to IVB injections.


Deep convolution networks (CNN) is applied to inverse the rough surface parameters, including the root-me an-square height and the correlation length, from microwave images. We employ computational electromagnetic method to simulate the training data for deep CNN. The simulated backward scattering data is converted into microwave images as the inputs to the CNN. An inversion network of deep convolution neural networks with five cascaded convolutional-maxpooling layers and two fully connected layers is designed, including feature extraction and data regression by using convolution layers and fully connected layers. The simulated results demonstrate the feasibility to inverse the sough surface parameters from electromagnetic scattering fields by using deep CNN.


The research project in which the following work is framed include the comparison of costs provided by the Argentine Chamber of Remanufacturing with the costs calculated by GEMPRO (The Study Group for the Improvement of Organizational Processes) in a local remanufacturer, by the using of an Activity Based Costing (ABC) system.
This work compares the activities offered by the Remanufacturing Chamber on its website, with the activities detected. It was possible to detect that, of all the activities, the Chamber of Remanufacturers does not include 56% at the calculation of costs. An analysis of the activities was carried out in a preliminary visit in a local remanufacturing company, concluding that 66% of the costs are due to Workforce.


ABSTRACTIn Jung's Ethics, Dan Merkur, a psychoanalyst in Toronto and the author of many books on the Inuit, psychoanalytic theory, mysticism, and drug-induced religious experience, here writes for the first time on Jungian psychology. Merkur is not abandoning Freud for Jung. A Freudian he remains. But he seeks to contrast Jung positively to Freud. Merkur draws scores of contrasts. Some of them are already known, some not. But even when the contrasts are known, Merkur illuminates them. He is especially concerned with the difference between Freud and Jung on the relationship of psychology to religion. Where Freud seeks to replace religion by psychology, Jung seeks to make psychology itself religious. Whether Jung in fact succeeds in tying psychology so tightly to religion, as Merkur contends, is considered.


Author(s): Soriano, John | Abstract: Forming Tibetan TaipeiOn a humid afternoon about five years ago, just off a narrow alleyway bordered by homogenous rows of five-storey apartment structures that line much of the crowded1, subtropical metropole of Taipei City, inside a Tibetan restaurant that occupied the ground floor of one of those narrow buildings, I sat, ostensibly doing ethnography, but really playing with the food I had just ordered. Of course, these two specific events of doing ethnography and playing with food are not necessarily contradictory...


A method that extracts segments in 2D range images from LIDAR(light detection and ranging) for mobile robotic localization and mapping was presented.The method included two stages,splitting and merging.In the first stage,a set of points was split recursively with IEPF,and then the end points of all the sets were reconfigured by using the principle of LT segmentation method.In the second stage,two situations are corresponding to the number of points included in two adjacent sets of points,and two adaptive threshold merging methods were used accordingly.The merging stage was also a recursive process.Experimental results show that the method presented in this paper well resolved over-splitting and over-merging problems in exacting segments.The end points of segments are denoted more accurately.


This research aims to know the Effect of Variations in Learning Methods and Family's Guidance on students' Learning Achievement for Christian Education of Class XI in the SMA Swasta Parsaoran. This research used a quantitative approach with descriptive inferential data analysis, with the population of all the students of Class XI in SMA Swasta Parsaoran consists of 117 students and it was taken 30 students as a sample of the research similar with 26% population. The instrument of the research was closed questionnaires which of the arranged by the researcher. The tryout was done for 30 students out of the was sample of the research. The number of the questionnaires items were 60 of which 40 item for variable x and 20 items for variable y, and the result showed good validity and reliability. The result of research analysis, concluded: 1) there were positive and significant effect of variations in learning methods on student learning Achievement for Christian education, 2) there were positive and significant effect of family's guidance on student learning Achievement for Christian education, 3) there were positive and significant effect Variations in Learning Methods and Family's Guidance on student's Learning Achievement for Christian Education. It means, that to increase students' learning Achievement for Christian Education, the Variations in Learning Methods and Family's Guidance need to be improved


The study evaluates the pathological manifestations found in reinforced concrete structures in 11 public buildings used for teaching purposes. The methodology used to characterize and analyze the types of pathology in this building was the one that estimates the Degree of Deterioration of Structures (GDE), which makes use of formulas and organization of data collected in the field. The case study was developed through an in loco inspection of the structural elements of the buildings, classified in blocks, and photographic record of the same; subsequently, the elements that presented pathology were analyzed and their degrees of deterioration were determined. Through this study, it was possible to observe the main pathology and occurrences that were found in these buildings, highlighting the spots (29.0%); humidity (28.5%); cracks (25.5%) and other pathologies (17%), which include arrows, efflorescence, carbonation, corrosion, insufficient coverage and segregation.


Collectivism is the important content of spiritu al civilization.The foundations which collectivism lives on still exist.Surely,i t still is our central value idea.Collectivism played an indelible role in the d evelopment of the socialist market economy.When we are adhering to the practice of collectivism under the conditions of the socialist market economy today,we mu st have a bet ter understanding of the character of collectivism at the socialist elementary s tage.We should treat collectivism with developmental viewpoint,keep advances wit h times,develop what is useful and discard what is not useful of old principles of collectivism,and constantly perfect our collectivism in the new situations.


In the following chapters, I discuss several works of film, video and photography made since the early twentieth century depicting Inuit and other Indigenous peoples of North America. Their creators have been motivated by a desire to produce a record, through various methods of reconstruction, of past ways of life of their Indigenous subjects. In the context of these efforts, the question of how to structure the material to attract and hold the attention of an audience has been a primary concern. The films discussed in chapters two and three exemplify ethnographic filmmaking as a visual and narrative practice of salvage ethnography. In contrast, the films and videos discussed in chapters four and five are examples of Indigenous media—that is to say, media produced by Indigenous people and communities—that make use of ethnographic, or simply cultural, reconstruction in a way that assumes the continuing vitality of Indigenous cultures and a healthy balance between past and present. Focusing on the example of Canada's first Inuit-made feature-length fiction film, Atanarjuat: The Fast Runner, I argue that the film's success and significance is grounded in a respect for traditional Inuit storytelling practices and an experiential approach to teaching that uses video as a proxy for directly "showing how," an effort to make traditional Inuit cultural memory and stories relevant to Inuit and wider audiences in the present and future.


2. A rapid growth of organisations involved in conducting entrepreneurship development programmes and consequently an upsurge in the number of EDPs being conducted. More often than not these EDPs only include 'training programmes' for potential entrepreneurs, rather than being comprehensive packages of developmental interventions for potential entrepreneurs in which training, though significant. is only one of the inputs.


type="main" xml:id="poms12400-abs-0001"> Firms often cite cost savings as a reason why they charge separately for add-ons. Firms also often face situations where consumers' price sensitivity is correlated with their valuation of add-ons. While cost savings may directly translate into profit gains in some scenarios, this study examines the strategic implications of add-on pricing and is the first to suggest that cost savings from add-on pricing may in fact result in profit loss for firms when consumers are heterogeneous in price sensitivity. This is because add-on pricing can trigger a revenue loss that exceeds any cost savings, thus leading to a negative net profit change for competing firms. Even if firms have the capability to pre-commit to not adopting add-on pricing, we show that competing firms can be locked in a prisoner's dilemma where all choose to adopt add-on pricing and lose profits (as compared to none adopting add-on pricing). We further show the possibility that the greater the cost of providing the add-on (and the greater the cost savings generated from add-on pricing), the worse this profit loss gets.


The article is dealt with current influence of ship's turning. The analytic relations for parameters of ship motion
with current influence obtained


Series of atmospheric PM2.5 samples were collected from an urban site of Wuhan in summer and winter of 2009.These PM2.5 samples were analyzed by gas chromatography-mass spectrometry(GC-MS) method to investigate the composition and variation of hydrocarbons in PM2.5.The result indicated that the concentration of PM2.5 was ranged 25.0-302.4 μg/m3,with higher loading in winter than in summer.The n-alkanes with carbon number of 11 to 34 was detected in PM2.5 samples,high carbon number alkanes possessed significant odd even predominance with carbon predominance index(CPI) was between 1.1 and 2.9,and great difference existed in the hydrocarbons distribution between winter and summer.These characteristics indicating the mixed inputs of PM2.5 from higher plant wax and anthropogenic source.The detected hopanes and steranes were indicative of fossil fuels residue input,while the influence was relatively predominant during winter period.The high molecule weight PAHs were significant components of hydrocarbons,together with diagnostic parameters,indicating the PM2.5 in Wuhan was predominantly polluted by motor vehicle traffic activity.


This study aims to determine the relationship between learning outcomes and learning independence of teknologi mekanik with interest in entrepreneurship in class X programs and engineering technology skills in the Teladan Vocational High Scholl Year 2013/2014 . The research method was descriptive correlational . The population was all students of class X programs engineering expertise and technology in the Teladan Vocational High Scholl field consisting of one class is a class X TR and numbered 45 people . In this case , the sample is determined by Krejci and Morgan table where the sample was taken is about 40 people . The data was collected by using a questionnaire to learn independence and interest in entrepreneurship while to learn the results of mechanical technology using documentation . Total instrument independent learning and interest in entrepreneurship as much as 30 statements on the questionnaire contained 25 statements independent learning which is valid with very high reliability 0.909 classified . While the interest in entrepreneurship there are 28 statements were declared invalid by 0.936 as very high reliability . The data analysis technique used is the product moment correlation analysis , partial correlation analysis and multiple correlation analysis at significance level of 5 % . Based on the analysis of the data shows that there is a positive relationship between learning outcomes and the means of teknologi mekanik with interest in entrepreneurship (r = 0.445) and there is a positive and significant relationship between independent learning with interest in entrepreneurship (r = 0.436) and found there is a positive and significant relationship between learning outcomes and learning independence mechanical technology with interest in entrepreneurship (r = 0.595) . The coefficient of determination between the outcome variable studied teknologi mekanik with interest in entrepreneurship by 19.86 % , and the coefficient of determination between the independent learning of 19.01 % interest in entrepreneurship and determination koefisiean between learning outcomes and learning independence teknologi mekanik with interest in entrepreneurship by 35.45 % . Summary results of the regression analysis are as follows : Fb = 10,160 price Ft = 1.64 at the 5 % significance level , so that Fb > Ft ( 10,160 > 1.64 ) . That the regression equation Y = 31.77 + 0.39 X1 + 0.38 X2 can be justified to draw conclusions about the relationship between learning outcomes and learning independence teknologi mekanik with interest in entrepreneurship .


Community Service for the Covid-19 Disaster (PKM-BC19) is the theme Community Service Program (KKN) thematic Faculty of Agricultural Technology, Andalas University.Service activities are more focused on Covid-19 volunteers who are tasked with educating the public. Students accompanied by lecturers carry out activities individually at their respective residences and occasionally come downdirectly to residents while still adhering to health protocols.The location for the implementation of student KKN is in Limbukan Village, South Payakumbuh District, Payakumbuh City. The work program carried out during KKN includes main activities, supporting activities and multimedia activities. The main activities are activities related to Covid-19. Supporting activities are activities related to economic, environmental, social improvement and public education.Additional activities or multimedia activities that students do are making educational videos which are then uploaded to social media such as Instagram, WhatsApp and Youtube.


Because it is an iterative process involving complexity and thoughtfulness, writing is a challenging activity requiring the writer to possess strong metacognitive talents. W-tier players skilled at what they do often have a high metacognitive strategy knowledge (MSK) and can effectively employ strategies. The metacognitive skills and knowledge (MSK) that a person possesses about writing indicate both their knowledge that can be verbalized and their awareness of higher order cognitive processes such as memory and comprehension, which are the fundamental building blocks of efficient writing. The MSK that a person possesses about writing indicates that they have knowledge that can be verbalized. When evaluating students' metacognitive abilities in academic writing in higher education, there are not a lot of evaluation tools available that can be used with large samples and in group settings. This is because evaluating metacognitive abilities in academic writing is relatively new. This article's major purpose is to give a step-by-step guide to constructing a new MSK testing tool, which will be its primary focus throughout its whole. There are three writing scenarios to choose from on the Multiple-Scenario Knowledge test (MSK), and each correlates to one of the three levels of self-regulated writing. In these scenarios, you will need to plan out a text before writing it down in its entirety, keep an eye on your progress while you write it, and then edit it once you have finished. The newly developed MSK test possesses high levels of content validity, is trustworthy, and can be applied at an affordable cost, as indicated by the findings of a preliminary study that included 51 participants and two trials that each included a total of 113 individuals each. In addition, the study found that the test could be applied at an affordable cost. The findings also provide proof of the new instrument's external validity by illuminating links between students' employment of metacognitive strategies and the quality of their writing. This article dissects the consequences that this revelation has for both existing and future academic investigation, as well as for the delivery of teaching, and it does so in light of the topic at hand.


Abstract : Conducting silver and gold coatings on silicon Attenuated Total Reflectance (ATR) plates have been employed as transparent electrodes to monitor in situ surface electrochemistry. The multiple internal reflection Fourier transform infrared spectroscopy (MIRFTIRS) technique, used previously to study redox reactions on platinum and iron films, is applied in this work to the study of adsorption processes in the double-layer region, in particular, the adsorption of thiocyanate on silver and gold. The MIRFTIRS spectra were found to be essentially free of solution band interference and are compared to surface IR spectra of the same system obtained by other methods. Spectra of thiocyanate adsorbed on gold and silver surfaces have been recorded as a function of applied potential and thiocyanate concentration. Evidence of thiocyanate species absorbed to gold via both nitrogen and sulfur atoms has been obtained, while only S-bound thiocyanate was clearly observed on silver.


This research paper explores rural tourism and tourism development in the islands. The aim of this research is to learn about rural tourism, opportunity and sustainability in the Islands. The article is based on primary sources of data collected from tourists in North and Middle Andaman District. The Chi-square test result shows that there is a significant association between the educational qualification and income of the respondents. The finding of the study reveals that there is a significant relationship between income and expenditure of the respondents. The finding of the study reveals the lack of inadequate facilities faced by the respondents. Rural tourism is one of the best industries for developing in this region. Rural tourism and local administration focused to enhance rural Tourism in North and Middle It generated income generation and employment opportunities at local level.


Introduction Writers. editors, and others involved in the documentation process , are increasingly becoming active participants in the &rend towards moving hardcopy documentation online. The process of implementing softcopy documents involves addressing many complex issues. If online information is to be provided for a diverse product set to users across a variety of operating systems, then the process of researching the potential for online information becomes even more complicated. At SAS Institute, our diverse, but integrated set of software products added an additional challenge: our ultimate goal would be to create not just hypertext, but hyperdocuments-online information combining hypertext and hypermedia with other software applications (see Martin, 1990). In short, we were faced with the challenge of exploring portabIe online information applications to document a wide-range of software products. The key question we needed to address was " What should our online information actually look like under different operating systems, for different products, and for different segments of our user population? " There are many different ways to try and answer this question. For example, you can explore the feasibility of using online information and hypertext by purchasing hypertext software or consulting with outside experts. In any case, it is heIpful to be able to explore features and functionality of several different online information applications within your organization before committing resources to either purchasing or developing hypertext software systems. Permission to copy without fee all or part of this material is granted provided that the copies are not made or distributed for direct commercial advantage, the ACM copyright notice and the title of the publication and its date appear, and notice is given that copying is by permission of the Association for Computing Machinery. To copy otherwise, or to republish, requires a fee and/or specific permission. This paper discusses how writers and programmers worked together to address this question and others by prototyping hypertext applications using capabilities of existing products available in one software system. Developing within the context of an integrated set of software products provided the additional opportunity to create and test several types of online information; from utility applications to text-intensive online documents. The purpose of this paper is to provide insights and suggestions for designing and prototyping portable online information applications gained from this research and development effort This paper illustrates how you can often combine aspects of different products , taking advantage of features such …


Introduction
Biliary strictures that developed after LT are managed with endoscopic retrograde cholangiography (ERC), percutaneous transhepatic cholangiography (PTC), or surgical revision. In cases where conventional endoscopic access is failed, alternative treatments should be achieved by means of the rendezvous technique, which is a hybrid technique combining PTC and ERC. We describe a rare case of necrotic pseudocyst occurring after the Rendezvous technique for treatment of post-transplant biliary strictures.

Methods
A case review has been done.

Results
A 65-year-old man who presented with hepatocellular carcinoma complicating chronic hepatitis B liver cirrhosis underwent live donor liver transplantation (LDLT) from his son. One year after, he presented mild pruritus. The serum liver enzymes and bilirubin level raised but, liver biopsy was not diagnostic of rejection. ERCP showed stricture of the biliary anastomosis and tried to PTC and ERC, but failed three times. Cannulation of a biliary stricture can be achieved by the Rendezvous technique with progressive balloon dilation and the placement of two plastic stents. The patient was readmitted 2 weeks later with pain and vomiting with fever. CT showed 17 cm large pancreatic necrotic pseudocyst which was possibly a complication of previous intervention. Percutaneous drainage (PCD) of the collection yielded abscess. Despite of drainage and antibiotics management during 4 weeks, symptoms and pancreatitis were not resolved. After repositioning of PCD and irrigating with saline daily, symptoms including fever have improved.

Conclusions
Necrotizing pancreatic pseudocyst has been happened rarely as a complication after post-ERCP in liver transplantation patients. and needed intensive treatments and long-term hospitalization for preventing fatal course.


Reuse the best practices and know-how capitalized from existing Software Process Models is a promising approach to model high quality Software Processes. This paper presents a part of an approach for software processes reuse based on software architectures. This contribution is based on exploiting Software Process know-how and the solution proposed after the study of existing work on software process reuse field, our study focuses on approaches for reusing based on software architectures and based on domain ontology. AoSP (Architecture oriented Software Process) approach, deals with the engineering "for" and "by" reusing Software Processes, it exploits the progress of two research fields that promote reusing for the Software process reusing: domain ontologies and software architectures. AoSP exploits an domain ontology to retrieve, describe and deploy software process architectures. This article details the engineering "for" reusing SPs step of AoSP, it explains how the software process architectures are described and discusses the software process ontology conceptualization and Software Process knowledge acquisition is done.


N-Trimellitylimido-L-isoleucine (3) was prepared from the reaction of trimellitic anhydride with L-isoleucine [L-2-amino-3-methylvalerianic acid or (2S,3S)-2-amino-3-methyl-n-valerinic acid] in an N,N-dimethylformamide solution at the refluxing temperature. The direct polycondensation reaction of the monomer imide diacid (3) with 1,4-phenylenediamine, 4,4′-diaminodiphenylmethane, 4,4′-diaminodiphenylsulfone, diaminodiphenylether, 1,5-naphthalendiamine, 2,4-diaminotoluene, and 1,3-phenylenediamine was performed in a medium consisting of triphenyl phosphite, N-methyl-2-pyrolidone (NMP), pyridine, and calcium chloride. The polycondensation was performed under two different conditions: in one method, the reaction mixture was heated in an NMP solution at 60, 90, and then 130°C for different periods of time, and in the other method, the reaction mixture was refluxed only for 1 min in the same solvent. The resulting poly(amide imide)s (PAIs), with inherent viscosities of 0.21–0.37 dL/g, were obtained in high yields. All of these compounds were fully characterized by IR spectra, elemental analyses, and specific rotation measurements. Some structural characterizations and physical properties of these new optically active PAIs were examined. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 89: 116–122, 2003


The invention relates to a method for synthesizing alkaline earth metal vanadate micro/nano materials by adopting a hydrothermal/solvothermal method. The method is characterized by taking ammonium metavanadate and alkaline earth metal salt as raw materials, one or more of sodium hydroxide, potassium hydroxide, hydrochloric acid and nitric acid as a system pH value regulator and one or arbitrary combination of two or more of distilled water, methanol, ethanol and acetone as a solvent, and applying a one-step hydrothermal/solvothermal synthesis method to controllably prepare the alkaline earth metal vanadate micro/nano materials. The invention has the following advantages: the alkaline earth metal vanadate micro/nano materials with different dimensions, microstructures and morphologies are selectively prepared by changing reaction experiment parameters; and target products have the advantages of regular morphologies, uniform sizes, good crystallinity and the like. The synthesis method provided by the invention has the characteristics of mild reaction, good repeatability, simple operation and the like. The materials can be widely used in the fields such as energy storage and transformation, catalytic degradation, biomedicine, aerospace, permanent magnet superconduction and the like, and have promising market prospects and development potentials.


Classical psychometric methods have been used to demonstrate the validity and reliability of the 42‐item Fear of Cancer Recurrence Inventory (FCRI). Our aim was to expand on this evidence with information on the discriminative value of the individual items when administered to people with a personal history of melanoma, using an item response theory (IRT) approach.


Static force data obtained at the NASA Ames Research Center 12 foot Pressure Tunnel are presented in plotted form for a 1/7 scale, single-engine, low-wing general aviation airplane model. The configurations tested included the basic airplane, various airfoil shapes, tail designs, fuselage strakes and fuselage modifications as well as airplane components. The test conditions included an angle-of-attack and sideslip range of -8 to 90 and -10 to 30 degrees, respectively, at a Mach number of 0.2 for Reynolds numbers of 288,000 and 3,450,000. The data are presented without analysis.


T he Ebola epidemic that surged in 2014 and continues into 2015 (hereafter, the 2014 Ebola outbreak) is the largest in history, primarily affecting three countries in West Africa—Guinea, Liberia, and Sierra Leone. A small number of cases were reported in Mali, Nigeria, Senegal, and Democratic Republic of the Congo (DRC), but these countries intervened early and effectively to limit disease transmission. A handful of cases have also been reported in countries outside of Africa, including Spain, the United Kingdom, and the United States (World Health Organization [WHO], 2015a). In August 2014, WHO declared the Ebola outbreak in West Africa a public health emergency of international concern, or PHEIC (WHO, 2015a). The organization's International Health Regulations (IHR) serve as the international framework for global disease detection, response, and obligations related to PHEICs. The IHR define several core capacities that all states must develop and maintain to "prevent, protect against, control and provide a public health response to the international spread of disease, in ways that are commensurate with and restricted to public health risks, and which avoid unnecessary interference with international traffic and trade" (WHO, 2005). Governments in West Africa, along with many international partners, including the United States, have been working to contain the disease and prevent its spread. The way that the 2014 Ebola experience has played out, three countries in West Africa have become disease havens, while four others in the region have not. The successful experiences of the latter countries in eliminating the Ebola threat are important for two reasons. First, Nigeria and Senegal serve as crucial economic and transport hubs in the region, and an epidemic there would have been catastrophic, increasing the region's isolation and reducing Mitigating the Impact of Ebola in Potential Hot Zones


Carrying capacity and stocking rate on Grazing Grassland are always the study emphasis in grassland ecosystem.Researchers have done lots of work aiming at research methods for carrying capacity and stocking rate.This article analyzed current study situation and development tendency about research methods for carrying capacity and stocking rate.


The task of extracting and classifying entities is at the core of important Health-NLP systems such as misinformation detection, medical dialogue modeling, and patient-centric information tools. Granular knowledge of textual entities allows these systems to utilize knowledge bases, retrieve relevant information, and build graphical representations of texts. Unfortunately, most existing works on health entity recognition are trained on clinical notes, which are both lexically and semantically different from public health information found in online health resources or social media. In other words, existing health entity recognizers vastly under-represent the entities relevant to public health data, such as those provided by sites like WebMD. It is crucial that future Health-NLP systems be able to model such information, as people rely on online health advice for personal health management and clinically relevant decision making.

In this work, we release a new annotated dataset, HealthE, which facilitates the large-scale analysis of online textual health advice. HealthE consists of 3,400 health advice statements with token-level entity annotations. Additionally, we release 2,256 health statements which are not health advice to facilitate health advice mining. HealthE is the first dataset with an entity-recognition label space designed for the modeling of online health advice. We motivate the need for HealthE by demonstrating the limitations of five widely-used health entity recognizers on HealthE, such as those offered by Google and Amazon. We additionally benchmark three pre-trained language models on our dataset as reference for future research. All data is made publicly available.


Abstract. Floating lidar systems (FLSs) are widely used for offshore wind site assessment, and their measurements show good agreement when compared to trusted reference sources. However, some influence of motion on mean wind speed data from FLS has to be assumed but could not have been quantified with experimental methods yet because the involved uncertainties are larger than the expected impact of motion.
This study describes the motion-induced bias on horizontal mean wind speed estimates from FLS with the help of simulations of the lidar sampling pattern of a continuous-wave (CW) velocity–azimuth display (VAD) scanning wind lidar. Analytic modeling is used to validate the simulations. It is found that the mean bias depends on amplitude and frequency of motion, the angle between motion and wind direction, and wind speed and strength of wind shear. The simulations are used to quantify the measurement deviation that is caused by motion for the example of the Fugro SEAWATCH Wind LiDAR Buoy (SWLB) carrying a ZX 300M profiling wind lidar.
The strongest bias of −0.67 % of the measurement values was estimated for a test case with "strong" waves aligned with the inflow wind direction. Under "normal" wave conditions the bias is smaller.
The reason for these low errors lies in a fortunate combination of the frequencies of lidar prism rotation and tilt motion.


Introduction: The aim of the study is to compare length of hospital stay, transfusion rates, and re-intervention rates during hospitalization for transurethral resection of the prostate (TUR-P), open prostatectomy (OP), and laser therapy (LT) for surgical treatment of benign prostatic obstruction (BPO). Methods: URO-Cert is an organization, in which clinical data of prostatic diseases from 2 university, 19 public, and 3 private hospitals and 270 office-based urologists are collected in order to document treatment quality. Data on diagnostics, therapy, and course of disease are recorded web based. The analysis includes datasets from 2005 to 2017. Results: Of 10,420 patients, 8,389 were treated with TUR-P, 1,334 with OP, and 697 with LT. Median length of hospital stay was 6 days (IQR: 4–7) for TUR-P, 9 days (IQR: 7–11) for OP, and 5 days (IQR: 4–6) for LT (p < 0.001). Risk for a hospital stay ≥7 days was higher for OP versus TUR-P (OR: 7.25; 95% CI = 6.27–8.36; p < 0.001) and LT (OR: 17.89; 95% CI = 14.12–22.65; p < 0.001) and higher for TUR-P versus LT (OR: 2.47; 95% CI = 2.03–3.01; p < 0.001). OP had a significantly higher risk for transfusions than TUR-P (OR: 2.44; 95% CI = 1.74–3.41; p < 0.001) and LT (OR: 3.32; 95% CI = 1.56–7.01; p < 0.001). Transfusion rates were not significantly different between TUR-P and LT (OR: 1.36; 95% CI = 0.66–2.79; p = 0.51). Risk of re-intervention was not different between all 3 approaches. Conclusion: OP was associated with higher transfusion rates and longer hospital stay than TUR-P and LT. Risk of transfusion was not different between TUR-P and LT, but TUR-P was inferior to LT concerning length of hospital stay. Re-intervention rates during hospitalization did not differ between the groups.


Abstract:This paper takes up a hitherto unnoticed 1844 Spanish translation of "A Madman's Manuscript," an interpolated narrative appearing in chapter 11 of The Pickwick Papers. I argue that the translation was likely the work of Guillermo Macpherson (1824–98), latterly Spain's leading Shakespeare translator; and that the translation must be direct, as the source text had been omitted from versions in French, the most likely mediating language. In analyzing the translation, I find evidence both of inexperience and of renderings consistent with the translator's profile as a heritage speaker. In contextualizing the translation, I document the expatriate and binational Anglophone readerships around Cádiz, where the translation was issued, and examine how English print, in British or continental editions, reached Spanish markets in Dickens's lifetime. I argue that English print reached Cádiz in primarily British editions, by sea, making Andalusia's Englishknowing readers a suggestive case of the diasporic history of print.


This study attempts to explore how relative income contributes to the autonomy of women at both personal and household levels. The potential problem of endogeneity, or reverse causality, in examining the link between female autonomy and relative income is addressed using the Instrumental Variable (IV) estimation approach. The years of education of a woman and her husband are used as instruments for the woman's relative income. Along with the use of exogenous variables as instruments, the heteroskedasticity present in the data is also exploited to form instruments for the relative income of women. The results of this study suggest that relative income unambiguously improves autonomy of women in household decision making but its beneficial effect on autonomy in personal decision making was not found to hold true in all the model specifications (with alternative identification schemes) as employed in this study.


This research is aimed to analyze the impact of social media use and functionalities towards brand equity with an empirical study of Mall X. Mall X's Instagram is being analyzed throughout this research. Furthermore, this research attempts to examine the impact of social media use and functionalities on brand equity elements simultaneously and individually. Data processing methods used in this research are validity and reliability test and classical assumption tests, while simple and multiple linear regressions are used as data analysis methods. Online questionnaire is used to collect data of 111 respondents. These research findings show that identity and conversation use and functionalities have significant impact on brand awareness simultaneously and individually, sharing and presence use and functionalities have significant impact on brand associations simultaneously and individually, reputation use and functionality has significant impact on perceived quality, and relationship use and functionality has significant impact on brand loyalty. Keywords:  Social Media, Brand Awareness, Brand Association, Perceived Quality, Brand Loyalty


of this Working Paper ................................................................ 1 Indications of contributions to IRDR Science Plan and UN Agendas ..................... 2 Main recommendations to DRR policy ........................................................ 3 Main Text ......................................................................................... 4


This paper discusses the development of Goa as a tourist site within India and examines the economic, cultural and environmental impacts of such tourism development upon Goan communities. In so doing, the paper argues that while Goa has become a dispensable space for the exigencies of contemporary tourist development it has also engendered various forms of resistance to this process. The paper utilizes Manuel Castells' notion of 'resistance identity' and David Harvey's notion of 'militant particularism' to interpret some of these resistances. In Goa, these have taken the form of 'active minorities' whose most immediate source of self-recognition and autonomous organization is their locality: resistance is practised, at least in part, as a defensive articulation of identity to protect collective resources.


Five filamentous fungi isolated from the upper S1,S2,S3,S4 in AI-Nasiriya governorate by using dilution method. The results showed that Aspergillus niger and Peniclllium funiculosum were more common fungi among other appearance percent of A. niger, Peniclllium funiculosum reached to 100%, and A.versicolor appear with 75%, but the percent of A.ostianus reached to 62.5%, (25%). The results showed that the different sites in present study were no high effect on fungal diversity in a sediments of marshe because the similarity of environmental conditions in study sites. The results s were the highest resistance to anthracene anthracene. Statistical methods obtained no significant differences between fungi, incubation with anthracene . The dry weight of both fungi were also resistant to anthracene. Mixed to fungal was appear A.niger + P.funiculosum the highest resistance to 2.0 mg anthracene in of axenic culture of of P.funiculosum was higher than control ,but the mycelia dry weight of of axenic culture of A. was lower than control. The statistical methods obtained non significant differences between fungi in po with anthracene. The results showed that both fungi can degraded anthracene to other compounds.


: This study investigates the constitution of the development of hybrid identity in young Australian Chinese from the perspective of language applied. The literature review focuses on bicultural and bilingual, and Chinese as heritage language. The guiding research questions is: How Language applied strategy used by 2 and 1.5 generations Chinese immigrants in Australia to develop their hybrid identity. Data was drawn from a focus group collected from three participants. It is grounded in the third space theory. It suggests that hybrid identity formation in Australia for young immigrants involves a fluid, diverse and complex cultural identity formation. The experiences of bilingual applied shape their hybrid identities. Australia as a third space provides the ground for constructing interplays between culture, environment, and community.


Zaire. Wilkie and Curran's report, "Why Do Mbuti Hunters Use Nets?" (AA 93:680-689, 1991) is an exemplary instance; and, though they remain unconvinced of its applicability to the Ituri, I am deeply grateful to them for their careful consideration of my Sepik hypothesis of hunting technology (Roscoe 1990). Based principally on data from the Sepik Basin of Papua New Guinea, I have argued that where ground-level vegetation density is high, visual environments are obscured and game is biased toward terrestrial species, thus favoring use of the spreadnet. By contrast, in lower density vegetational environments, game is more evenly distributed among avian, arboreal, and terrestrial species, and visibility is less obscured, thus favoring archery. Wilkie and Curran find this an insufficient explanation of Ituri hunting technology. In my view, however, there are three reasons why their evidence provides, as yet, an insufficient basis for rejecting the validity of the Sepik hypothesis in the Ituri.


Background: The treatment of people living with AIDS , known a highly active antiretroviral therapy (HAART), has increased considerably, and the disease has therefore acquired chronic features. Several changes have been observed, especially in cardiovascular disease risk. Objective: To assess cardiovascular risk in HIV/AIDS patients treated with HAART and compare this with Lipodystrophy Syndrome (LS) carriers. Methods: This is a descriptive cross-sectional study. 192 patients were recruited from a lipodystrophy outpatient centre, using Framingham risk scores. Results: After criteria inclusion/exclusion, the final sample consisted of 81 patients divided into two groups (HIV/AIDS - without lipodystrophy and HIV/LS - with lipodystrophy). The mean age of HIV/AIDS was 46.5 years, and of the HIV/LS patients was 52 years. In accordance with Framingham scores the cardiovascular risk in HIV/AIDS was 46.59% and 14.29% in HIV/LS. Conclusion: The risk of cardiovascular disease over 10 years is significantly higher in patients with lipodystrophy syndrome.


Building on the Ramsey-de Finetti idea of event exchangeability, we derive a characterization of probabilistic sophistication without requiring any of the various versions of monotonicity, continuity, or comparative likelihood assumptions imposed by Savage (1954), Machina and Schmeidler (1992), and Grant (1995). Our characterization identifies a unique and finitely-additive subjective probability measure over an algebra of events. Copyright The Econometric Society 2006.


On the basis of a significant number of unpublished documents, here published for the first time, the article reconstructs the historical and scientific origins of Lavoisier's Mémoires de physique et de chimie. Because of the paucity of primary sources available so far, this work has previously received little attention and its 'publication' is commonly attributed to Madame Lavoisier's effort to revive the memory of her husband. In contrast with this image, this article suggests that Madame Lavoisier had only a subsidiary role and that Armand Séguin's contribution to both the editing and the scientific organization of the Mémoires needs a historical reassessment. Lavoisier's collaboration with Séguin, dating from 1792, resulted in a work the aim of which was far more ambitious than that of collecting already published memoirs. Furthermore, it is argued that the contents of the first volume of the Mémoires indicate an important evolution in Lavoisier's chemical theory.


This article describes the changes that are being experienced in the global trade in pears. Its purpose is to know if the processes of integration among countries are affecting their competitiveness in the international trade. Regarding the methodology utilized for this report, the Competitiveness Foreign Trade Index (CFTI) analyzes the competitiveness of a country for a particular product with its tariff nomenclature, covering its main export destinations, monitoring the rate of participation in accordance to the trends markets reflect, and thereby, assessing the competence. The result is seen clearly: The global trade competitiveness in pears is regional rather than global, resulting in being competitive solely on nearby markets subject to commercial agreements. The main solution would be related to an improvement of adapting their markets to a global dimension to increase competitiveness for their trade mark.


Joint decoding at base stations combined with cooperative transmission is investigated to improve the uplink throughput of current cellular systems over fading channels. In this paper, we consider amplify-and-forward (AF), decode-and-forward (DF) and hybrid decode-amplify-forward (HDAF) cooperation schemes between relay stations. We analyze the throughput of direct transmission (DT), AF, DF, and HDAF both in single-cell and multi-cell respectively. A linear mesh network is considered where a single mobile terminal for each cell communicates with a local base station via a dedicated relay, which can be AF, DF, or HDAF. All of the base stations in the mesh network decode the received signals cooperatively.


Objective: The purpose of this study was to investigate the possible protective effects of Zygophyllum gaetulum aqueous extract on hypercholesterolemia and oxidative stress in rats fed a high-cholesterol diet.
Methods: Twelve hypercholesterolemic rats were divided into two groups fed a 20% casein diet enriched with 1% cholesterol + 0.5% cholic acid and supplemented (HC-Zg) or not (HC) with Z.gaetulum extract (1%), for 4 weeks.
Results: In the HC-Zg group compared with the HC group, plasma total cholesterol and low density lipoprotein cholesterol concentrations were respectively 1.5- and 2.4-fold lower, while high density lipoprotein cholesterol levels were higher (+50%). Thiobarbituric acid reactive substances (TBARS) concentrations were decreased in plasma ( 76%). Moreover, TBARS concentrations were respectively 4-, 3.2-, 1.8- and 3.4-fold lower in liver, heart, brain and aorta. Superoxide dismutase (SOD) activity was respectively 4- and 1.2-fold higher in liver and aorta. Increased catalase (CAT) activity was noted in liver (+14%), heart (+27%) and aorta (+17%), while glutathione peroxidase (GSH-Px) activity was respectively 2.3- and 1.6-fold higher in liver and aorta. An important glutathione reductase (GR) activity was noted in heart (+14%), brain (+47%) and aorta (+23%). Reduced glutathione (GSH) levels were respectively increased by 78, 35 and 65% in liver, heart and aorta.
Conclusion: These results show that Zygophyllum gaetulum aqueous extract improves hypercholesterolemia and oxidative stress induced by a high cholesterol diet and consequently may protect against cardiovascular diseases.


Through analyzing the particularity of bidding in large-scale infrastructure project, this paper set up an offered model of game theory which is fitted for a special large-scale infrastructure project, and introduced computer modeling technique to solve the model, provided to bidder optimum bid offered tactics. This method was then applied to the bid instance of a large-scale tunnel project in a city.


This paper investigates the effect of chemical reaction and radiation on flow of a micropolar fluid on continuously moving plate with suction or injection. The plate is moving with a constant velocity in the chemically reacting micropolar fluid. The radiative heat flux and the viscous dissipation are taken into account in the energy equation. The partial differential equations governing the flow have been transformed into system of ordinary differential equation using similarity transformation and then solved numerically by fourth order Runge-Kutta method with shooting technique. The velocity, microrotation, temperature, and concentration are shown graphically for different value of suction or injection parameter and chemical reaction parameter. The rate of mass transfer for different values of chemical reaction parameter is also shown graphically and it shows that mass transfer is highly depending on chemical reaction parameter.


The Epidauria. A standard, indeed a classic, work, L.Deubner, Attische Feste, in the course of a rughly-praised section on the Mysteries, deals with the Epidauria. The Epidauria, wruch honored Asklepios, were a one-day festival which can hardly have existed with that name, and for that deity, before the formal introduction of Asklepios. Deubner determines the day of the Epidauriil. as 18 Boedromion, the day before the procession to Elemds. (Without independent investigation, I assume trus is correct.) The principal event ofthe Epidauria was another, lesser nop,nl], the course of wruch presumably was within the limits of Athens. During the time of trus procession, the Mystai remained in their houses.


In the video we present the Bridging Book, a mixed media picturebook that blurs the line between physical and electronic books. We present also the technical implementation of the prototype. In this prototype the illustrations of a children picture book are complemented by the digital content on a digital tablet placed next to it. Thumbing through the physical book pages displays synchronized content on the tablet. The narrative contents can be explored by reading the physical book and further exploring the interaction on the digital media. The physical book requires no batteries or wires.


A new device is proposed that combines a surface-wave memory with an acoustoelectric convolver to yield an adaptive real-time correlator and convolver. The principal difficulty in combining these devices is obtaining short intense electron bursts in a small gap between a piezoelectric and a semiconductor.


Most switchboards are used for a long term of about 30 years. As for the switchboard, the situation of the use and maintenance is individually and greatly different. So the life-expectancy presumption technique of the switchboards has not been established. We executed the deterioration diagnosis for the switchboards that had been used for 30 years. We paid attention to the surface deterioration of the insulation materials that is the main element that decides the life-expectancy of the switchboards. We evaluated the life-expectancy presumtion technique of aged switchboards based on MTS (Mahalanobis Taguchi system) method. This technique attracts attention in recent years. And we confirmed the presumption result was corresponding to the result of the verification with temperature controlled bath actually.


Excerpt To the editor: I read with great interest the statement of the Federated Council for Internal Medicine on manpower in the January issue (1). The statement is an appropriate answer for the s...


In foundation excavation of a nuclear power plant,the blasting vibration should be controlled strictly in order to ensure the safety of bedrock and nearby buildings and structures.The authors presented the whole process of vibration monitoring and vibration reduction method based on the foundation excavation of the nuclear island.The in situ blasting tests reveal that shock absorption holes can reduce the blasting vibration.The vibration velocities of rock particles increase with hole spacing,and decrease with hole diameter.It is more efficient in practice to reduce blasting vibration by reducing shock absorption hole spacing than by extending hole diameter.


Atomic‐scale modeling and understanding of materials have made remarkable progress, but they are still fundamentally limited by the large computational cost of explicit electronic‐structure methods such as density‐functional theory. This Progress Report shows how machine learning (ML) is currently enabling a new degree of realism in materials modeling: by "learning" electronic‐structure data, ML‐based interatomic potentials give access to atomistic simulations that reach similar accuracy levels but are orders of magnitude faster. A brief introduction to the new tools is given, and then, applications to some select problems in materials science are highlighted: phase‐change materials for memory devices; nanoparticle catalysts; and carbon‐based electrodes for chemical sensing, supercapacitors, and batteries. It is hoped that the present work will inspire the development and wider use of ML‐based interatomic potentials in diverse areas of materials research.


Introduction: Health literacy includes the cognitive and social skills which determine the motivation and ability of individuals to access, understand and use information to promote good health. People with lower health literacy do less well in the NHS and are less likely to adopt health self-management strategies than people with higher levels of health literacy. There is no published research exploring the impact that lower health literacy levels have on individuals managing the consequences of musculoskeletal (MSK) disease. This study explored the impact of lower health literacy levels for people living with a MSK disease Methods: Key contacts identified potential participants from Rheumatology clinics, GP surgeries, Colleges and community groups. Participants over 18 years, with a MSK disease and either thought to have lower health literacy or self-identifying as having lower health literacy were included. Participants completed a Rapid Estimate of Adult Literacy in Medicine (REALM) and demographic questionnaire. Semi-structured interviews were audio-recorded, transcribed and analysed thematically. Findings: Nine women and nine men aged 29-82 years participated. This group were predominantly white British, and most completed high school education. Ten participants had a lower level of literacy (i.e. scored Discussion: People with lower levels of health literacy and MSK disease manage complex social and co-morbid medical conditions. Information provided by health professionals is not always useful and many relied on their social networks for support. People recalled that often they had been told that there was nothing that could help their pain or arthritis; it couldn't be cured. This impacted negatively on the incentive for people with lower health literacy to recognise and engage with self-management approaches. To better support people with lower health literacy and MSK conditions to engage with self-management strategies, all agencies need to emphasise the potential benefits and use easily accessible clear messages to communicate these.


Triple‐negative breast cancer (TNBC) has higher mortality than non‐TNBC because of its stronger metastatic capacity. Increasing studies reported that TNBC tumors had more macrophage infiltration than non‐TNBC tumors, which promoted the metastasis of TNBC cells. However, how TNBC cells become more malignant after interacting with macrophages is less reported. In this study, it is observed that when TNBC cells are co‐cultured with macrophages, they display higher viability and stronger metastatic ability than non‐TNBC cells. Mechanistic studies reveal that TNBC cells acquired these abilities via interactions with macrophages in three phases. First, within 12 h of co‐culture with macrophages, some TNBC cells have significantly elevated levels of reactive oxygen species (ROS), which upregulate interleukin 1α (IL1α) expression in ERK1/2‐c‐Jun‐ and NF‐κB‐dependent manners at 24−48 h. Second, the secreted IL1α bound to IL1R1 activates the ERK1/2‐ZEB1‐VIM pathway which increases metastasis. Third, IL1α/IL1R1 facilitates its own synthesis and induces the expression of IL1β and IL8 at 72−96 h through the MKK4‐JNK‐c‐Jun and NF‐κB signaling pathways. Moreover, a higher level of IL1α is positively correlated with more macrophage infiltration and shorter overall survival in breast cancer patients. Thus, reducing ROS elevation or downregulating IL1α expression can serve as new strategies to decrease metastasis of TNBC.


The Spring and Autumn Period was the "axis times" in the history of Chinese culture.During the period,the form and concept of dragon drew particular attention,especially the concept of dragon changed from the specific representation level to the Abstract symbolic level and was crystallized in Yi.


The use of alternate bids with life cycle cost as part of the tender process for pavement choice evaluation has been evolving in Canada since the first contract was tendered in 2001. The purpose of this paper is to review the history of alternate tenders in congruence with life cycle costs that were originally begun in Ontario with the Life Cycle Cost study of 1995 and then will proceed to identify and consider when undergoing a life cycle cost analysis (LCCA). The use of equivalent bids, selection of accurate maintenance and rehabilitation (MR Highway 410, Highway 417 East and West, and three sections of Highway 401 in Ontario; and Deerfoot Trail and Anthony Henday Drive in Alberta, and will discuss some of their details, including asphalt and concrete pavement structures, maintenance and rehabilitation schedules, tender costs for the two pavement structures, life cycle cost analysis period and discount rates used in the analysis.


Method of increasing growth of soybean plants comprising treating soybeans or soybean plant that germinates from the seed with an effective amount of at least one CO where after harvesting the plant shows at least one performance plant increased measured for bushels / acre, number of increased roots, root length increased, mass increased root volume increased root and leaf area increased, compared to soybean plants untreated or soybean plants harvested seed soybean untreated, wherein at least one CO comprises a CO represented by the formula; ** ** formula wherein R1 and R2 each independently represents hydrogen or methyl; R3 represents hydrogen, acetyl or carbamoyl; R4 represents hydrogen, acetyl or carbamoyl; R5 represents hydrogen, acetyl or carbamoyl; R6 represents hydrogen, arabinosyl, fucosyl, acetyl, sulfate ester, 3-0-S-2-0-MeFuc, 2-0-MeFuc, and 4-0-ACFUC; R7 represents hydrogen, mannosyl or glycerol; R8 represents hydrogen, methyl, or -CH2OH; R9 represents hydrogen, arabinosyl, or fucosyl; R10 represents hydrogen, acetyl or fucosyl; n represents 0, 1, 2 or 3.


The amount of fuel remaining in the tanks of an airplane in flight may be determined in two ways: (a) by measuring the liquid levels in the tanks; or (b) by measuring the fuel as it is consumed and subtracting from the amount on board at take-off. The oscillating-piston type of displacement meter has been used successfully in the latter system. This paper describes two such meters, and gives data on the accuracy of this method of fuel measurement.


This paper presents a study of the effect of imperfect power control on the performance of a Partial Parallel Interference Cancellation (PPIC) multiuser receiver. We show that the PPIC receiver can absorb the effect of imperfect power control to a great extent compared with other types of receivers. Additionally, the effect of imperfect power control on the optimum weights of the PPIC receiver is considered. It is found that imperfect power control causes the receiver to become more susceptible to performance degradation as a result of deviation from optimal weights.


cDNA segment of corn starch branching enzymes gene was obtained by PCR techinque and cloned into pMD18-Tvector.The recombinant clone was detected by PCR technique and analysed by the restriction en-zyme.A full length of cDNA gene was sequenced.The results showed that the length of the clone sequence is1698bp.The gene was inserted into binary vector in reverse orientation and constructed antisense vector.


Method of maintaining the vibration of the vibrating device, and discloses a vibrating device for carrying out the method. Vibration device is intended to be attached to the unit to be attached to the body, such as watch, case and a movable mass for transmission of vibrations to it be internal to this case, it is electromagnetically coupled to the movable mass a coil (L) for vibrating the, and an excitation circuit for exciting the coil (L). Alternating polarities in a predetermined duration drive pulse having a Each drive pulse (21, 22) is generated at the end of the movement induced voltage .FIELD 4B


Aim: This study was aimed at identifying Indian field isolates of Avibacterium paragallinarum on both molecular as well as serological levels that cause infectious coryza in chickens. Materials and Methods: Species-specific polymerase chain reaction (HPG-2 PCR), and 16S ribosomal RNA (rRNA) sequencing were employed for molecular identification. Whereas, multiplex PCR technique was used for serological identification of Indian field isolates of A. paragallinarum. Results: All three field isolates were identified as A. paragallinarum using HPG-2 PCR. The species-specific PCR results were validated using 16S rRNA sequencing. The partial 16S rRNA sequences obtained from all three isolates showed 96-99% homology with the NCBI database reference strains of A. paragallinarum. The aligned partial sequences of 16S rRNA were submitted to GenBank, and accession numbers were obtained. Multiplex PCR-based molecular serotyping showed that there are three serotypes of field isolates of A. paragallinarum, namely, strain IND101 is serovar A, strain IND102 is serovar B, and strain IND103 is serovar C. Conclusion: HPG-2 PCR, 16S rRNA sequencing, and multiplex PCR are proved to be more accurate, sensitive, and reliable diagnostic tools for molecular and serological identification of A. paragallinarum field isolates. These diagnostic methods can substitute conventional cultural characterization and would be much valuable to formulate quick and correct prevention and control measures against this detrimental poultry pathogen.


While research on Warring States, Qin, and Han manuscripts is flourishing, much less is known about the use of manuscripts during the earlier stages of Chinese history, for which material evidence has not been preserved. Based on the layout features and textual anomalies in the Western Zhou bronze inscriptions, this article explores the traces of use of perishable writing supports in the process of the production of bronze inscriptions in this period and reconstructs their functions and physical qualities. Based on the surveyed evidence, the article posits that two distinct exemplar manuscripts were used in the inscription-making process: an original "master copy" that was kept aside for proofreading purposes and a secondary "blueprint" that was employed directly in the technical process of inscription-making. A single blueprint would be used consecutively by several craftsmen to produce a set of inscriptions on different types of vessels. The word count and layout of many inscriptions were already carefully planned during the process of their composition, and any study of a bronze text should therefore begin with the evaluation of its visual qualities. Moreover, this probe provides unambiguous evidence for the use of tube-lining in the inscription-making process and reconstructs the complete chaîne opératoire of bronze inscription production in the Late Western Zhou period. The article also offers insights into the level of literacy and the division of labor in bronze workshops, and touches upon the display function of bronze epigraphy during the Western Zhou period.


A study to determine the effect of ozone mixed with carbon dioxide on controlling stored-grain insects was conducted in the storehouse. Adults of Sitophilus oryzae (L.), Tribolium castaneum (Herbst), Rhyzopertha dominica(F.), Oryzephilus surinamensis(L.) and 3 th larvae of Plodia interpunctella(Hubner) were exposed to the mixture of ozone and carbon dioxide. After exposure periods of 24 h, the insects were transferred to clean jars containing food and held at 27±2 o C and 65 ±5% R.H. Experiments were performed in different heights (30, 40, 50 and 100 cm) and nutrition materials (date, wheat and rice), in penetration tests and empty-space tests. In empty-space trials, the highest mortality was for P. interpunctella. In penetration tests, treatment with high-pressure ozone and carbon dioxide under different height and foodstuff may result in different rates of mortality. The mixture of ozone and carbon dioxide in the interaction between height and diet (heigh×diet) are not significant for the S. oryzae, T. castaneum, R. dominicaand P. interpunctellabut for O. surinamensis is significant. The influence of ozone gas and carbon dioxide in the date is more than rice and wheat. The mixture of ozone with carbon dioxide can be as suitable fumigant for decreasing phosphine and methyl bromide under ambient storage conditions in penetration and empty-space fumigations.


This paper describes the community involvement and the impact that the Department of Mechanical, Industrial and Manufacturing Engineering (MIME) at the University of Toledo (UT) has accomplished during the past six years with its senior students in developing custom devices for physically disabled individuals within the Toledo community. These projects assist disabled individuals to better enjoy life and realize their maximum potential. These projects significantly enhance the education of student engineers through the experience of designing and building devices to meet a real need with feedback on how well the device satisfies that need.


Detergency is a complex procedure comprising both chemical and mechanical processes. In order to fully understand the chemical process, it is necessary to uncover its basic steps by setting up a simplified modeling system. In this study, we attempt to find the key to the detergency mechanism by revealing the adsorption of enzymes and surfactants onto proteins and the degradation and subsequent release of the proteins using a quartz crystal microbalance (qcm) measurement that can quantify minute weight changes in water over time. We first examine three different proteins—gelatin, ovalbumin(OvA), and keratin. The frequency change of a qcm is traced for the release of solid protein by Nagarse® from the surface of a gold electrode. As observed in former studies of dissolved protein, the synergistic effects are confirmed for release by protease/nonionic surfactants, i.e., C12(EO)7 and C16(EO)7. Adding anionic surfactants—sodium dodecylbenzene-sulfonate (dbs) or sodium dodecylsulfonate (sds)—enhances the release rate at near the critical micelle concentrations. The amount of adsorption of the enzyme to gelatin increases in the presence of anionic or nonionic surfactants.


Valley Religion" [New York: Macmillan, 1986]) suggests the need to rethink quite radically the nature of "continuities" between the Indus and later data.' Finally, one senses that, even given the literary and "great traditional" emphasis that Kinsley has adopted, there are certain points of convergence that will be apparent to all, including beginning students. Why, for instance, is there such a recurrence of regal imagery in the portraits of different goddesses? Does there not appear to be here an implicit connection between divine and earthly power? For all of the tremendous difficulties that would be involved in writing it, Kinsley's book would have benefited from a general chapter on the place of feminine deity in India, if only to point out the current points of disagreement. In such a chapter recent anthropological and structuralist exploration of the relation between goddesses and kings could, among other matters, have been included, and Kinsley's synthesis made still broader.


The importance of the development of information management system based on user-defined date control was discussed firstly; the universal methods of development of user-defined control in VB.NET were introduced and compared with each other. aiming at the shortcoming of the date control in VB.NET, the process of the development of user-defined date control on the platform of VB.NET and the methods used during it were described detailedly and some skills were dissertated which may give directions to other control development. the application of the control was introduced finally.


The block printing has both cultural and commercial characters. A cultural center, which has a basis of business and trade and many scholars and men of letters, can provide redoubled development opportunities than other places. There were close relations between the change of regional cultural structure and the block-printing center in Fujian. The center had a shifting process from the location in Jianyang of North Fujian to Tingzhou Sibao of West Fujian and then to provincial capital Fuzhou in history . The rise and decline of the press was a barometer of cultural development.


A follow-up investigation was made into the change of teachers' educational background in the compulsory education and it was supposed that such academic titles as the discipline leaders and backbone teachers can fully represent teachers' teaching competence.Through the advanced statistical analysis,some correlations are found between teachers' initial diploma,current diploma,normal diploma,non-normal diploma and their teaching competence.There is a negative correlation between the initial diploma and the teaching competence,while sometimes a positive correlation and sometimes a negative correlation between the teaching competence and the final diploma are found;there is a positive correlation between the teaching competence and the final normal diploma and the initial normal diploma,but there isn't a high correlation between the teaching competence and the diploma.Therefore,the authorities should be strict in recruiting both primary and middle school teachers and strengthen the in-service training.


Atorvastatin, a highly lipophilic anti-hyperlipidemic drug, has poor oral bioavailability (14%) due to hepatic first pass effect. The present study aimed at developing an optimal oral nanoemulsion formulation containing an atorvastatin using different proportions of oil and surfactant systems for enhancing its oral bioavailability. Pseudoternary phase diagrams were constructed by aqueous titration technique and various nanoemulsion formulations were prepared. Formulations selected from the o/w nanoemulsion region were subjected to various thermodynamic stability and dispersibility tests. Optimized formulations were evaluated for various physicochemical characterization tests. The in vitro dissolution studies revealed that release of atorvastatin from nanoemulsion was faster than the conventional tablet (Ozovas TM ) and pure drug suspension. The formulation used for assessment of bioavailability contained 15% of oil (Oleic acid), 18% mixture of surfactants (Tween 80 and Brij 35), 6% of co-surfactant (ethanol) and 61% of double distilled water. The absorption of atorvastatin from nanoemulsion resulted in 2.87- and 2.38-fold increase in bioavailability as compared to conventional tablet and pure drug suspension respectively. Thus, the study confirmed that the nanoemulsion formulation can be used as a possible alternative to traditional oral formulation of atorvastatin to improve its bioavailability.


When thinking about linguistic justice we may have several intuitive ideas about what the implications of justice in the field of language should be. The first idea that may come to mind is the safeguard of minority languages in national states from being superseded by the majority language, and to the promotion of multilingualism. In the European Union the protection of the Member States' national language and the cultural heritage typically associated with it is realised by a complex system of translation of documents, legislation, case-law, work-meetings, and by the recognition of twenty-three official languages. Linguistic justice is then framed in national-cultural terms and convened into linguistic rights, protected by covenants and interpreted by courts. This is the rights-based approach that most legal scholars, philosophers, and political thinkers may refer to when talking about linguistic justice. It is refreshing to find in Philip Van Parijs' new book a formulation of issues of justice as referred to languages in a vital and powerful normative outlook. In a clear and decided tone, he reminds us in the introduction: "An articulate conception of what linguistic justice means and of what it requires supplies resources for undermining the arrogance of the powerful, for empowering the indignation of the powerless, and for guiding the judgement of anyone who might happen to be in a position to arbitrate" (p. 5). The national scene is abandoned for a more ambitious, worldwide reaching definition of what linguistic justice requires, and is linked to a protection of the most vulnerable. In other words, linguistic justice is turned into a matter of social justice that spans across the world. According to the author, issues of linguistic diversity arise because of three main factors: multilingual countries becoming democratic, the need to function in different languages and finally immigration, and the consequent permanent linguistic diversity it entails. All of these aspects are universal, and therefore it becomes relevant


Trust originates from England. It is built upon the dual legal system consisting of law and equity in England. Compared with Civil law system,dual legal system is peculiar to Anglo-American legal system. So civil law countries have to solve many problems when they transplan trust. But unfortunately,many of the theoretical problems hadn't been dealt properly by the legislator when the Trust Law is drafted,so it isn't applied efficiently in practice. Among the reasons that lead to the inefficiency of Trust law,the internal structure of trust ownership is principal. So the paper chooses the internal structure of trust as the subject. As the content of this article,it first analyses the relative provision of Chinese Trust law,and investigates the experiences of successful civil law countries,finally reconstructs the internal structure of trust ownership in China under the advanced experiences of other countries.


The research project EURIDICE (European Inter-Disciplinary Research on Intelligent Cargo for Efficient, Safe and Environment-Friendly Logistics) focuses on the development of intelligent solutions for the transport sector. The basic concept of EURIDICE is an information services platform centered on the individual cargo item and its interaction with the surrounding environment and the user. EURIDICE has promoted the Intelligent Cargo concept as a future solution for transport sector information needs. The platform will be implemented and tested in eight industrial transport scenarios. This paper looks at one scenario related to intermodal railroad operations. The paper presents the functionalities of the developed cooperative system for intermodal railroad operations and the way end-users can use the system environment in their operations.


The invention relates to an intake air filter (1) for an internal combustion engine, especially in a motor vehicle. The inventive filter comprises a filter housing (2) having a raw air inlet (4), a pure air outlet (5), and an annular filter element (3) which is arranged in the filter housing (2) and through which air can flow in a radial manner from the outside towards the inside. Said filter element comprises a first end disk (10) on the axial end thereof, said disk comprising an opening (12) by which means the pure air outlet (5) communicates with the inside (8) of the annular filter element (3). The aim of the invention is to reduce the influence of a secondary air induction on the fresh air supply of the internal combustion engine. To this end, the filter housing (2) comprises a secondary air outlet (6), on the pure air side, and the annular filter element (3) comprises a second end disk (11) on an axial end opposing the first end disk (10). Said second end disk comprises at least one opening (17) by which means the secondary air outlet (6) communicates with the inside (8) of the annular filter element (3).


An atypical wedge is exposed during construction of rear slope of the power house.Base on the parameters of fracture surface and geometry parameters of wedge obtained from field investigation,the first,sliding model of the wedge is determined by the method of stereographic projection of vector,the second,stability analysis in both natural conditions and saturated water are made by vector method,which provided some basis for the design of reinforcement in the late period.


The use of the block copolymers polystyrene-block-poly(ethylene oxide) and poly(methyl methacrylate)-block-poly(ethylene oxide) is described to assist the direct solubilization of single-walled carbon nanotubes (SWNTs) into water under ultrasonic irradiation. As compared to surfactants and homopolymers, the block copolymer systems may offer the potential of additional unique morphologies through self-assembly. TEM and AFM analyses of solution-cast samples indicate exfoliation and wetting of the SWNTs by the block copolymer. With increasing duration of ultrasonic irradiation, an increase in solution viscosity is initially found, which suggests that it is a convenient indicator of the progress of exfoliation of the SWNTs. With increasing duration of ultrasonic irradiation, an increase in solution viscosity is initially found, which suggests that it is a convenient indicator of the progress of exfoliation of the SWNTs. With continued intense ultrasonic irradiation, the solution viscosity may decrease apparently because of damage/breakage of the SWNTs.


Objective To detect the PTEN expression in bone marrow cells of patients with high-risk myelodysplastic syndromes(MDS),as well as to explore its clinical significance in high-risk MDS and relativity with disease development,and make a preliminary evaluation of its guide to predict prognosis.Methods The cases included 25 patients with high danger MDS,with a group of 24 patients with non-hematologic malignancies and normal bone marrow cells(pathological paraffin section)as control.The expression of PTEN was detected by sSP immunocytochemical staining(S-P method).We also did follow-up study on treatment response and disease prognosis of the 25 high-risk MDS cases.Results There were significant difference(P0.01) between positive expression rate of PTEN in high-risk MDS(56.00%) and control(90.00%).High-expression group and low-expression group were set up based on the integration of sample≥3 to determine PTEN expression levels:the high-expression group 8 cases and low-expression group 17 cases.There were differences between the treatment response rate of high-expression group(5/8 cases,62.50%)and that of low-expression group(8/17 cases,47.06%),but it was not obvious(0.01P0.05).In chromosome karyotype analysis of 25 high-risk MDS cases,there were 9 abnormal cases and 16 normal cases,and PTEN expression level showed no relativity with abnormal chromosome karyotype.In high-expression group,3 in 8 cases changed into acute leukemia(37.50%),and in low-expression the proportion was 11/17(64.71%).Conclusion Abnormal expression of PTEN gene exists in high-risk MDS patients,and it has some relativity with treatment response.Therefore,PTEN has a certain significance for prognosis of high-risk MDS.


The assemblies of a p-conjugated organic luminophore ligand (p-tr2Ph) and d10 transition metal cations produce two metal–organic frameworks (MOFs), [Zn(μ4-p-tr2Ph)(μ2-NO3)]·NO3 (1), and {[Cd2(μ4-1,4-BDC)2(μ4-p-tr2Ph)(μ2-DMF)(H2O)2]}·2H2O (2) (p-tr2Ph = 1,4-phenylene-4,4′-bis(1,2,4-triazole), DMF = N,N′-dimethylformamide, 1,4-H2BDC = 1,4-dicarboxybenzene). Compound 1 is a new three-dimensional (3D) cationic framework with left-handed helical channels constructed from a right-handed helical chain [Zn(μ2-tr)2(μ2-NO3)]n. Compound 2 possesses a 3D 3-fold interpenetrated neutral framework with one-dimensional distorted hexagonal channels in each MIL-88 type single-net. The compounds 1 and 2 both exhibit blue fluorescence. Notably, the intensity-based luminescent thermometer measurements reveal that compound 2 is extremely more linear with temperature, has finer reversibility within three cycles, and a wider temperature range than those of compound 1, indicating that compound 2 is a more desirable low-temperatur...


I grew up surrounded by words, by language, by books, by stories. My father was a masterful storyteller, and created tales in which my four siblings and I were the characters. We learned by osmosis - geography, zoology, history. Perhaps even more pertinent, we were lulled into good behaviour. Dad's stories were told at the breakfast table, once we were all present, all dressed ready for school, all eating our breakfast. As a consequence, we were always on time for the school bus.


The relationship among fatigue, intensity of effort, and pacing strategies during exercise has not been conclusively defined. The article describes 3 models of fatigue. In the first, the peripheral model, muscle metabolic factors control or dictate the onset of fatigue and the reduction or termination of exercise. In the second model, the central-teleoanticipatory model, subconscious-brain centers or functional activities set predetermined exercise activity in a feedforward manner, maintaining a reserve of functional capacity as a protective mechanism. In the third model, the cognitive-discussion model, the sensation of fatigue itself controls exercise intensity in a feedforward manner within the framework of the subconscious teleoanticipation limits, using prior activity as the comparator to set and maintain levels of exercise intensity. Physiological and anatomical structures available in the latter 2 models to control exercise intensity might include central pattern generators, multiple-joint spatial-pattern recruitment, and motor-unit-recruitment variation.


Analytical solutions for Muskat-Leverett (ML) and Buckley-Leverett (BL) models of immiscible fluid filtration in porous media are obtained. These solutions are used for testing the difference schemes. The testing example for the problem on conjugation of ML and BL models is also constructed.


A rare and unique variant of breast cancer--metaplastic matrix producing carcinoma, is presented. Surgery has been the mainstay of treatment. The role of adjuvant postoperative radiotherapy, as has been used in this patient, has been reviewed.