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Three Challenges That Come With Transitioning from Graphic to UX Design, and Tips to Overcome Them
by Linn Vizard
posted on 08-31-2017
The new economy means that most people will change careers at least once in their lifetimes. In some cases these changes are drastic (quitting your executive position to be a yoga teacher – anyone?), and in others, they are natural evolutions or lateral moves. For many graphic designers, the move to User Experience design (UX) is one that often happens organically.
The decline of the print industry and growing focus on designing for digital means that graphic designers are increasingly considering what it means to design for screens. In tandem with that, the heightened strategic importance of design for many products and services means that designers must consider their work beyond the visual aspect.
All of that said, career transitions are not a walk in the park, and although graphic design and UX have many overlapping or transferrable skills, designers will face challenges along the course of this transition.
Expanding Your Skillset
Having graphic design knowledge and experience is certainly an asset to the aspiring UX designer. While it's a great base to start from, there are additional skills that are important to acquire through learning and practice. The biggest shift is in designing for use – creating products and systems that people use to complete a task, rather than communication pieces that people view and absorb information from. This means understanding principles of usability, being able to conduct design research, facilitate workshops, and rapidly prototype and test ideas.
This skills gap can feel overwhelming – so what's a graphic designer to do? As UX is a relatively young discipline, there are few formal degree programs, and many practitioners are self-taught through a combination of reading, experience and shorter educational programs. The good news is that there are lots of ways to level up your UX knowledge:
- Devour as much UX material as possible! Read everything you can, and listen to podcasts. The Rosenfeld Media books are a great place to start, as well as podcasts such as the UX podcast, the Dollars to Donuts design research podcast, and of course the Creative Cloud blog!
- Join UX communities, such as the IxDA, Michael Wong's Designership, or the Interaction Design Foundation. These communities regularly host webinars, workshops and meet ups that can support learning.
- Consider online courses, evening classes or boot camps for a more structured approach. There are some great beginner resources to get started with, or you can read more about the options available and how UX education is evolving.
Remember that theoretical learning is a great start, and that what you learn needs to be applied through your work, side projects or personal projects.
Feeling Pigeon-Holed as a 'Pixel Pusher'
For many graphic designers looking to make the transition to UX, this can be the most frustrating barrier. Great graphic design skills and visual polish and be a distraction for some employers, and you may feel pigeon-holed as someone who 'makes things pretty.' The advantages of visual design skills are a double-edged sword; many students I've worked with have felt this pain, where they end up being seen as more suited to UI or graphic design work, even though they are longing to do more UX focused work.
It's important to not get discouraged if this happens. Overcoming this challenge is all about knowing how to represent yourself and your work, and how to use those visual design skills to your advantage! Some approaches to this challenge include:
- Make sure to represent work in the appropriate way for a UX designer in your online portfolio. This includes showing and emphasizing process, (e.g. including sketches and wireframes or early iterations) and articulating how design decisions are connected to research, insights and an understanding of user needs.
- Choose the right level of visual polish for the work you show in a portfolio or in an interview. You may want to tread carefully and initially de-emphasize the branding and visual design elements of the work. This is a judgement call you need to make in each situation, but if you are frequently finding yourself in the visual design box when it's not where you want to be, think about changing up the polish and fidelity of work you show.
- During interviews, emphasize the importance of the design process and iteration. For graphic design, often what matters is a stunning end result. For UX design, your approach to solving problems and how you think about them is often what a potential employer is trying to assess. It's crucial you demonstrate that you know how to learn about users, and how to apply those insights to the design of an experience.
Presenting yourself and being seen as a UX designer will take some time and practice as you are learning a new mindset. It's ok for this to take time, just stick with it!
Getting Your Foot in the Door
As with any career transition, getting started is often the hardest part. For many designers, landing the first job or opportunity to flex your UX muscles takes a lot of time and perseverance.
- One mistake that people sometimes make is fixating on getting 'the perfect job'. Chances are, your first UX job might not tick every single box you are after, and that's ok. Focus on getting your foot in the door somewhere that you can be relentlessly useful as you are learning – diving in is the best way to develop your career.
- Startups can be an environment where as a designer you can take on UX and learn by doing. However, beware that this is a challenging environment, sometimes without much mentorship, so it's not for everyone.
- Another option that's especially relevant to graphic designers making a transition to UX is to look for split UX/UI roles. While there is much debate about design 'unicorns,' a role that requires your graphic design chops can be a great starting point.
- Internships and junior positions can be in great demand, but are of course an ideal starting point. Look for known programs that take on designers, in tandem with building your network and offering your services to smaller companies.
- Doing your own side and personal projects in the meantime, or freelancing, can be a great way to practice skills and build your portfolio.
Getting your foot in the door is definitely a challenging phase of any career transition. This challenge is all about staying positive and persevering!
Genius is One Percent Inspiration, Ninety-Nine Percent Perspiration
As a graphic designer hoping to transition to UX, you have a great starting point. Being aware of some common pitfalls and strategies to overcome them will help you on your journey. As Thoman Edison said, it's "ninety-nine percent perspiration."
Topics: Creative Inspiration & Trends, Design
Products: Creative Cloud


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E-Commerce platforms are generally viewed as a relatively modern element of an enterprise stack. But in our view, it is one area that is significantly overdue for renovation. In this research note we examine the role that a headless commerce concept can play in helping to modernize e-commerce capabilities.
Commerce and Payment Platforms
Research Coverage
Companies large and small are searching for new sources of top line and bottom line growth, often by entering markets or new business models. New products and services are being launched, driven by ever-shorter cycle times and competitive pressures. During the product life cycle the need for agility remains and in turn, this is placing renewed demand for flexible billing and monetization solutions that can handle today's requirements for business agility, ease of use, and rapid implementation times. Further, the on-premise systems of the past are lagging the market requirements. For companies seeking to gain competitive differentiation through their monetization capabilities, success requires the right focus, independent advice and counsel, and experienced insights based on what leading companies have achieved.
The MGI Payment Strategies Catalyst (PSC) research assists executives, finance, and IT teams navigate the fast-moving market for Payments and monetization tools, platforms and services; evaluate vendors, negotiate contracts, optimize implementations, and ensure success throughout the journey to agile monetization. The PSC program helps clients save time, reduce risks, and achieve higher levels of corporate performance by applying best practices and continuous improvements. The program delivers confidential advice and actionable intelligence, all focused on providing clients with deeper insights into determining the best vendor fit for their requirements, getting the best price, terms and conditions during contract negotiations, and managing the implementation and on-going operations of their payments, commerce, finance, and business systems.
- What are successful strategies for optimizing authorization rates and eliminating payment friction?
- What Business Models are available and which ones are most appropriate for my business?
- What is the impact of the subscription and consumption-based business models on payment management?
- Which partners can deliver real value and bottom-line improvements?
- What mix of payment methods produce the best conversion?
- Who are the winning and losing vendors?
- How can I optimize my retention and build better relationships with my customers?
- Who are the emerging vendors that will be the leaders of tomorrow?
- What are the hidden risks and challenges when going international?
- What are the regulatory risks and opportunities on the horizon?
- What is an achievable best-in-class total cost of ownership for payments and related activities?
- MasterCard
- Visa
- First Data
- American Express
- Union Pay
- DataCash
- Asknet
- Cybersource
- WorldPay
- Elavon
- Credorax
- PayPal
- Vantiv
- Vindicia
- Digital River
- Chase Paymentech
- FastSpring
- Stripe
- Avangate
- Ingenico
- Cleverbridge
- Klarna
- BlueSnap
- Adyen
- PayPro Global
BlueSnap Acquires Armatic – A PayFac Edges Closer to Agile Billing
The Impact of Brexit on Digital Payments: How is Big Tech Getting Ready?
While major European and international financial institutions are consumed with crafting their Brexit coping strategies, Big Tech firms such as Google, Amazon, Facebook, Uber and others are forging ahead with new digital payment initiatives. What are the risks and opportunities for key players?
Worldline to Acquire Digital River World Payments
On July 17 2017 Worldline S.A. announced that it has reached an agreement to acquire Digital River World Payments (DRWP) from its private equity owner Siris Capital Group.
FinTech Summer Heat: European Payments Unicorns Become Banks; Investment, M&A Activity Heating Up
More Articles...
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subset: commoncrawl


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时间:October 8, 2020 at 12:00 PM until 1:00 PM Central Daylight Time
Building from a core in applied statistics, the Master of Science in Analytics provides students with advanced analytical training to develop their ability to draw insights from big data, including: data collection, preparation, and integration; statistical methods and modeling; and other sophisticated techniques for analyzing complex data. The program is highly applied in nature, integrating business strategy, project-based learning, simulations, case studies, and specific electives addressing the analytical needs of various industry sectors. Through partnerships with key employers, the program also provides students with applied projects and data sets as well as access to career networks and employment pathways upon graduation. Join us for this online information session to learn program details, admission requirements, and how you can get started.


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Carbon isotope evidence for a northern source of deep water in the glacial western North Atlantic
Edited by Edward A. Boyle, Massachusetts Institute of Technology, Cambridge, MA, and approved December 21, 2016 (received for review September 1, 2016)
Understanding glacial ocean circulation is tied to understanding heat transport in the North Atlantic, growth and maintenance of ice sheets, and atmospheric CO2 content. The proxy data are sparse, but, for decades, it has been thought that the North Atlantic did not produce deep water during the Last Glacial Maximum, unlike today. New C isotope results from a core at 5 km in the western North Atlantic indicate a young, glacial deep water may have been formed in the surface Labrador Sea by freezing and brine rejection. These data call for a revised circulation scheme where southern source water centered at 4.2 km would have been sandwiched between glacial North Atlantic intermediate water and the new dense bottom water.
The prevailing view of western Atlantic hydrography during the Last Glacial Maximum (LGM) calls for transport and intermixing of deep southern and intermediate northern end members. However, δ13C and Δ14C results on foraminifera from a sediment core at 5.0 km in the northern subtropics show that there may have also been a northern source of relatively young, very dense, nutrient-depleted water during the LGM (18 ky to 21 ky ago). These results, when integrated with data from other western North Atlantic locations, indicate that the ocean was poorly ventilated at 4.2 km, with better ventilation above and below that depth. If this is a signal of water mass source and not nutrient storage, it would indicate that a previously unrecognized deep water end member originated along the western margin of the Labrador Sea, analogous to dense water formation today around Antarctica and in the Okhotsk Sea.
Over the past 30 y, paleoceanographers have learned that during the Last Glacial Maximum (LGM), North Atlantic Deep Water (NADW) shoaled and was replaced by Antarctic Bottom Water (AABW) that was transported from the south (1, 2). This reorganization affected climate through distribution of heat, salt, and CO2. Carbon isotope results from a new sediment core at 5,010 m depth near Corner Rise (CR) Seamounts in the Sargasso Sea (Fig. 1) are the deepest paleo-data from the western North Atlantic, and they define a new mixing line between an LGM southern source of bottom water at 4.2 km and a young nutrient depleted northern source at 5.0 km.
Corner Rise Results
On R/V Knorr cruise 197/10, we surveyed the northern part of the CR region and cored the flank of an abyssal hill where 3.5-kHz sonar data show at least 50 m of sediment drape (Fig. 1D). Sediment collected from 5 km on CR by giant gravity core (GGC) 17 is very similar to the drift deposit at 4.4 km to 4.6 km on nearby Bermuda Rise (BR), but with more shells of the benthic foraminifer Cibicidoides (Fig. S1). Together with ice-rafted lithic particles, this genus reached peak abundance during the Heinrich Stadial 1 (HS1) interval on CR (Fig. 2B). Chronology of 17GGC is based on 11 accelerator mass spectrometer (AMS) 14C dates on the planktonic foraminifer Globorotalia inflata (Dataset S2), and linear interpolation assuming zero age at the core top. Ages are calibrated years before present, with only the standard 400-y reservoir correction [CALIB calibration program 6.1 (3)]. In general, sediment accumulated at 5 cm⋅ky−1 to 10 cm⋅ky−1, with higher sedimentation rates during a brief interval at the beginning of the Younger Dryas (YD; 40 cm⋅ky−1) and during the 3,000 y preceding the LGM (23 cm⋅ky−1) (Fig. 2C). The high sedimentation rate intervals may simply coincide with higher fluxes of glacial sediment to the deep ocean before events of cold climate, but we cannot exclude possible changes to the deep, southern recirculating gyre associated with the Gulf Stream (4). Absence of a sedimentation rate peak associated with the extreme cooling of HS1 may reflect remoteness of the site from the sources of Heinrich icebergs, but it is also consistent with minimal production of northern-source deep waters (2) and reduced sediment transport at that time.
The oxygen isotope history of 17GGC exhibits variability that is typical of the past 25 ky (Fig. 2A). The δ18O of Cibicidoides has a glacial−interglacial range of ∼2‰, about double the estimated ice volume effect (5), indicating local temperature and δ18O of water (or salinity) influences. Cibicidoides δ18O increased slightly into the LGM (∼18–21 ka), with mean LGM values of 4.34 ± 0.06‰ (n = 9). The δ18O decrease began between the sample dated to 17.0 ka and the next underlying sample interpolated to be 17.3 ka, and continued to the Holocene in steps centered on about 12 and 15 ka. These are the familiar Terminations 1A and 1B (6). The δ13C of Cibicidoides was close to zero during the LGM (0.06 ± 0.10‰), but, during HS1, it decreased by about 0.5‰ and stayed low until ∼13.5 ka, well into the Allerod. That half-permil decrease is comparable to the difference in δ13C of ΣCO2 between AABW and NADW in the modern ocean (7). Following the minimum in Cibicidoides δ13C, values increased late in the Bolling/Allerod epoch, decreased into the YD, and increased again in the Holocene. AMS 14C dates on Cibicidoides at 15.0 and 20.4 ka are, respectively, 1,300 and 1,200 14C years older than the G. inflata in the same samples.
Previous Work
Recently, as new core sites with higher-resolution sampling and more precise dating have become available, studies have identified temporal, spatial, and depth variability in stable isotope ratios of Cibicidoides that result from differences in bottom water properties during the LGM and deglaciation (8⇓⇓–11). These studies demonstrate it is possible to distinguish temperature and salinity effects on δ18O to show evolving bottom water temperature and salinity at different times and places. For example, it was reported that δ18O may have decreased earlier in the North Atlantic (17 ka on the Iberian Margin) than in the southwest Atlantic (15 ka) for sites at >3 km, and the decrease was larger (0.6‰) than can be accounted for by the secular change due to ice sheet melting (9). The decrease in δ18O at 17 ka is confirmed at CR, although the lead over South Atlantic δ18O is not significant because of uncertainty in the chronology there (9). However, the δ18O and Mg/Ca evidence for early freshening at 3.15 km along the Iberian Margin (12) suggests that some fraction of bottom waters at >3 km must have been generated by glacial melting and brine rejection during sea ice formation at a freshened high northern latitude surface, not the Southern Ocean (9). Before the present study, the early deglacial decrease in Cibicidoides δ18O had not been noted in the northwestern (NW) Atlantic because that genus is not consistently present in cores from its western margin.
Synthesis of Western North Atlantic C Isotopes
Although the δ18O on CR is typical of deep North Atlantic sites during the LGM, δ13C is higher than expected. This difference is seen by comparing the CR data to Cibicidoides data from other sites in the NW Atlantic in a depth profile for the LGM (Fig. 3 and Fig. S3). However, this compilation assumes little difference in properties between eastern and western locations in the NW Atlantic, which we can only support for paired analyses at about 2 and 3 km (Fig. S4). We interpret C isotopes in benthic foraminifera as quasi-conservative tracers for paleocirculation (5), although the data could reflect, in part, remineralization of biogenic C (13). The most recent analysis by Gebbie et al. (14) indicates that remineralization is less significant than previously thought, in essential agreement with Marchal and Curry (15), who estimated that organic matter remineralization makes little contribution today to the δ13C of ΣCO2 in the deep (>1 km) Atlantic.
From Carolina Slope sites (1 km to 2 km water depth), δ13C steadily decreased down Blake Ridge to 4.2 km (Fig. 3A). Below that depth, the trend reversed, with higher δ13C at 4.5 km on BR, 4.7 km on Bahama Outer Ridge, and 5.0 km on CR. The large uncertainty in δ13C from BR is most likely related to the high accumulation rate of organic matter as revealed by preserved diatoms and bivalves (16) and the possible effects of organic matter oxidation and bioturbation on δ13C. The slight decreasing trend in δ18O below 3 km may not be significant, although it would be consistent with the Iberian Margin evidence for freshening (12). However, the δ13C reversal below 4.2 km is large and suggests the largest fraction of southern source (low δ13C) water was centered on 4.2 km, with increased mixing of a relatively high δ13C source below that depth.
In addition to δ13C, other geochemical proxies for deep ventilation and circulation during the LGM point to a blend of southern and northern source waters in the NW Atlantic. For example, Pa/Th results (2) and Nd results (17) from BR consistently show that the glacial mixture of bottom water must have contained a northern component. This finding is at variance with the prevailing view that there was little or no northern deep water present in the glacial North Atlantic (18, 19), but a recent synthesis of Nd isotopes in the western Atlantic has also been interpreted as evidence for a glacial source of NADW (20). Furthermore, Böhm et al. (21) found that some interstadials and the last interglacial on BR had lower εNd than in the modern ocean. This very low εNd could indicate there were both warm and cold climate processes that formed deep water in the North Atlantic that are inactive today.
Ventilation estimates based on the difference in conventional 14C age between pairs of planktonic and benthic foraminifera (or bivalves) (14CB-P) during the LGM are consistent with the δ13C data (Fig. 3B). When the new CR data are added to previously published results from the NW Atlantic (16), and new results from the Laurentian Fan, Hatteras Abyssal Plain, and Blake Ridge (Figs. S5–S7, respectively), a similar pattern emerges that is interpreted here as decreasing ventilation down to 4.2 km, and increasing ventilation below that. McManus et al. (2) suggested that northern source export during the LGM was at intermediate depths over BR (glacial North Atlantic intermediate water), a result that was supported by later data (22). Our new CR results point to enhanced ventilation at least as deep as 5,010 m. Furthermore, lowest δ13C and highest 14CB-P at 4.2 km is consistent with grain size results in three depth transects of Blake Ridge cores that indicate the fast-flowing deep western boundary current of modern circulation (3 km to 4 km) deepened to >4 km during the LGM (23).
Unlike shallower locations where northern ventilation is thought to have resumed at about 14–15 ka (12), ventilation at 5 km on CR as represented by δ13C in Fig. 2 remained weak (between that of LGM and HS1) until ∼13.5 ka. However, results are ambiguous on BR. Whereas Pa/Th data indicate ventilation resumed 14–15 ka (2), δ13C indicates a 1-ky delay (Fig. S3). Either way, the available data suggest that postglacial resumption of ventilation in the North Atlantic evolved from the top down. That is, the tongue of glacial North Atlantic intermediate water thickened downward as suggested earlier (24), and more recently at sites >2.5 km off Brazil (10). Eventually, ventilation by convection in the Norwegian−Greenland Seas would have resumed, probably near the beginning of the Holocene.
Ocean and Climate Implications
What ventilation process could account for relatively young and nutrient-depleted water in the LGM NW Atlantic at 5 km? In the modern ocean, the densest waters are produced in the Nordic Seas by heat loss and mixing with cold Arctic waters, and around Antarctica by upwelling, heat loss, and brine rejection by freezing in polynyas and under ice shelves. During the LGM, much of the ocean heat transport to the Nordic Seas is thought to have been reduced, and new paleo-tracer data show deep Norwegian Sea waters were very old and nutrient rich (25), so we rule out the modern process in the Nordic Seas. Although oxygen isotope data indicate that brine rejection occurred in Nordic Seas (26), there is no evidence that enough dense water accumulated to spill over the sill at Denmark Strait (∼600 m).
Radiocarbon ventilation studies in the South Atlantic (27) and southwest Pacific (28) found a deep-water bulge in low Δ14C that is similar to what we observe in the western North Atlantic. The authors from both studies propose that deep waters during the LGM originated in the south, with relatively young northward flow underlying an aging southerly return flow. However, it should be noted that the bulge in the South Atlantic is defined by data at only three locations, and two have uncertain and different reservoir ages (29). Whereas a southern water mass origin is compatible with our results, the NW Atlantic data are far from the Southern Ocean data, with few between and none of >4 km depth. Instead, we seek a more local explanation, especially in light of the NW Atlantic Pa/Th, Nd, and the early decrease in δ18O on CR and the Iberian margin (12).
North Atlantic instrumental data suggest an alternative to an estuarine-type circulation driven from the south. The decadal observations that began in 1972 at Geochemical Ocean Sections Study (GEOSECS) Station 27 in Newfoundland Basin (Fig. 1) show that, using dissolved silicate as a tracer for AABW, bottom water between about 4 and 5 km had a variable AABW component (Fig. 4A). In 1972, there was a bulge of silicate at about 4.5 km that was undercut by low-silicate water that must have originated at Denmark Strait, according to the water properties mapped by Worthington and Wright (30). Not only is a northern source indicated by low silicate, but it is also supported by high Δ14C and tritium, each of which undercuts old water between about 4.3 and 4.5 km depth (Fig. 4C). This pattern of northern source water undercutting the southern source in Newfoundland Basin in 1972 was recorded by GEOSECS as far south as Station 28, but not as far south as Station 29 (Figs. 1 and 4B). Some of the pronounced silicate bulge in 1972 may be related to the negative phase of the North Atlantic Oscillation, which is hypothesized to cause enhanced convection in the Nordic Seas (31). The Newfoundland Basin ventilation changes are not exactly analogous to the LGM situation in the NW Atlantic because of the presumed absence of LGM convection in the Nordic Seas, but they show that the simplest way to produce a bulge in old water in the NW Atlantic is to introduce a local source of relatively young, dense water.
Accepting the evidence for old and warm bottom waters in the Nordic Seas during the LGM (25), we propose the Labrador Sea could have been a site of deep LGM ventilation by brine rejection around its margins. There is no direct evidence for this proposition, but it would have been facilitated by katabatic winds blowing down a Laurentide Ice Sheet that was grounded on the broad Labrador continental shelf. The LGM glacial till along the Labrador shelf is thought to have been deposited ∼20 ka by a retreating ice margin that may have formed an ice shelf (32), and a basin such as the Labrador marginal trough could have accumulated brine. Offshore winds also could have promoted ice growth, dispersal, and brine formation similar to the several latent heat polynyas around the Okhotsk Sea that produce, today, the densest water in the North Pacific Ocean (33).
In conclusion, we have shown that there may have been a third component of deep North Atlantic circulation during the LGM, thereby adding a new dimension to our view of water mass distribution in the glacial ocean. The new C isotope results support the same conclusion based on Nd isotopes (20). If this new source of bottom water resulted from brine rejection and not heat loss to the atmosphere, there may not have been the same climate impact as modern NADW production. The new deep northern component is indicated by the reversal in C isotope trends to higher δ13C and lower 14CB-P below 4.2 km in the western North Atlantic and more vigorous flow (23). Thus, in this view, water of southern source was sandwiched between glacial North Atlantic intermediate water and the new dense bottom water. The spatial extent of the deepest northern component can best be explored by new coring even deeper than 5 km near CR and up the west flank of the Mid-Atlantic Ridge.
We thank the officers and crew of R/V Knorr for several successful voyages, Bob Key for help with Fig. 4, and Mike McCartney for years of discussion about the NW Atlantic. We are grateful to G. Gebbie, D. Lund, J. McManus, L. Robinson, and O. Marchal for their comments on early drafts of this paper, and to Katsumi Matsumoto and an anonymous reviewer for their helpful suggestions. Thanks go to Luke Skinner for providing his data from the Iberian margin. This work was funded by National Science Foundation Grant OCE-0822854.
- ↵1To whom correspondence should be addressed. Email: Lkeigwin{at}whoi.edu.
Author contributions: L.D.K. designed research; L.D.K. and S.A.S. performed research; L.D.K. and S.A.S. analyzed data; and L.D.K. and S.A.S. wrote the paper.
The authors declare no conflict of interest.
This article is a PNAS Direct Submission.
See Commentary on page 2794.
This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1614693114/-/DCSupplemental.
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Samsung Galaxy J7 Prime 2 is now up for sale in India as per the reports. The smartphone was quietly launched last week by the company in the country.
The Samsung Galaxy J7 Prime 2 is currently available in the retail stores at Rs 13,990 and soon it might be available on Flipkart and Amazon as well.
The smartphone marks a 5.5-inch TFT LCD display with 16:9 aspect ratio, 1080 x 1920 resolution and 2.5D Corning Gorilla Glass on top. It is powered by an octa-core Exynos 7 series chipset clocked at 1.6 GHz. The device has 3GB of RAM and 32GB of built-in storage, which can be expanded up to 256GB via microSD card.
In terms of camera, the handset carries a 13MP rear camera with "Social Camera" feature, which allows the user to click, edit, and share pictures instantly. On the front, the phone has a 13MP camera with an f/1.9 aperture.
Galaxy J7 Prime 2 runs on Android 8.0 Nougat OS and marks 3300mAh battery. The handset comes in two colors – Black and Gold.
Shailesh Sharma


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Following a very weak performance during the first month of the current Iranian year, Tehran's real-estate market has registered a healthy growth in the number of residential deals during the second month to May 21.
The latest report by the Central Bank of Iran published on its official website, which employs data from the Tenement Management Information System, indicates that the number of home deals in Tehran during the second month of the current year reached 19,100, which signals a respective increase of 278.7% and 16.7% when compared with the previous month and the same month of last year.
As CBI pointed out in its report, the huge 278.7% increase is because traditionally, the first month of the year sees the lowest volume of home deals, as half of it is taken up by Norouz holidays. However, the first fiscal month showcased a performance even weaker than anticipated as only 5,000 residential deals were registered in Iran's capital, lower by 6.3% compared with the first month of the year before.


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My Alcoholic Husband Rapes Me Every Night And I Cannot Take It Anymore
My Alcoholic Husband Rapes Me Every Night And I Cannot Take It Anymore
I'm a child of the early 90s, just a normal girl with lots of dreams and wishes. I was a very bright student and a hardworking professional. I turned out to be just okay and fit into my roles well. Just like every other family, my family started forcing me to get married when I turned 25. It was not something that I hadn't expected but I was not ready to have a relationship and a family but since I was the only daughter and my mother had recently passed away, having a younger brother to look after, I had no choice but to get married to the man of my father's choice for the happiness of my family.
He was nice, and our likes and dislikes seemed to match so I thought I was marrying the right person.
Initial few days of my marriage was all hearts and roses and love in the air and my in-laws were very kind and considerate of my feelings. But all good things come to an end and so did my happiness. One day, my husband came home drunk and on questioning him he told me that it was his friend's birthday and they forced him to drink. I was a little mad at him, but he had his own romantic way of convincing me and I'm not ashamed of saying, the sex was always amazing.
From then on, he started getting drunk very often and he would not bother giving me any explanation also and my in-laws always took my husband's side in such situations.
The worst started happening after that, he would come drunk and not talk at all, he would force himself on me even if I protested and told him he's hurting me, and I don't want to do it. This started happening every day and my amazing sex life turned into a nightmare. I started dreading the nights and fearing his presence. I love him with all I have but he scares me, and he never listens to me or tries to understand me. During the day, he is such a nice person to me and looks after me so well but when he is drunk, he is a completely different person and he is not ready to stop drinking even though I tried to talk him out of it many times.
I don't know what to do. I can't leave him for his habits, but I can't take being raped every night.


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I'm going to lose twenty pounds and make myself look better to the opposite sex, but I'm not going to take anything with them seriously.
I'm going straight down to visit Danny when I get my license, and I am going to stay a few days there.
I'm going to write to an older peer and arrange for us to exchange the things that we borrowed of each other's.
I'm going to visit Mike and Mya more often.
I'm going to go to Exeter in the last weeks of summer and be able to kick ass when I come back.
I have half a mind it's cracked and breaking
It's recommended as great for tasting
Spit in the face of the tried and true
These are things that I'm gonna do
You go Melora!


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Skip to 0 minutes and 9 seconds So I'm now going to talk about the Descarte cohort, which actually addresses this in some detail. Because it allows us to look at whether antibiotics prevent complications and re-consultations and, in particular, what's the impact of delayed prescription, compared to an immediate prescription. So this is 13,000, more than 13,000 people– a huge cohort, the biggest prospective cohorts done to date. And the bottom line– complications are uncommon, no matter what you do, around 1%. And the complications are as you see– Quinsy, which is pretty rare; sinusitis; otitis media, a little bit more common; and cellulitis or impetigo, which happens, again, fairly rarely, but will occur. So the big question is, does delayed prescribing prevent those?
Skip to 0 minutes and 59 seconds Well, if you allow for the– if you like the propensity of GPs to prescribe antibiotics, which is very important to do in these observational studies, the adjusted risk ratios show that you get a risk ratio of 0.6 for antibiotics, means that there's a 40% reduction in complications. And for delayed antibiotics, there's a similar reduction– so roughly halving the complication. So basically, antibiotics or delayed antibiotics will halve your complications or thereabouts, between 40% and 50% reduction. So there's definitely something there for individuals that you're a bit concerned about, who might be more likely to get a complication.
Skip to 1 minute and 39 seconds The other thing that it's worth noting, which was very interesting to find, was delayed prescribing actually reduces re-consultations more effectively, in fact, than immediate antibiotics. So around 15% to 20% of people will come back within a month with either the same symptom or a progression of symptoms. And antibiotics will reduce that by 25%. So that's a risk ratio of 0.76. So that's about a 25% reduction. And the delayed antibiotic will reduce it by even a little bit more, so about 40%. In summary, really, what we've shown from the Descartes sore throat cohort– and actually, we've got very, very similar data coming out now from a big study in chest infections, a 3C cohort– complications are uncommon.
Skip to 2 minutes and 22 seconds But if you're considering an antibiotic, they certainly will reduce complications and re-consultations. Re-consultations are even better with delayed prescription. So if you're considering an antibiotic, I would consider a delayed prescription for most of the time you are considering an antibiotic. It prevents complications, reduces re-consultations, and it's at least as effective as immediate antibiotics and will lower your antibiotic use.
Does Back up/Delayed Prescribing Prevent Complications and Reconsultations?
Can Back up/Delayed Prescribing Prevent Complications and Re-consultations?
In this presentation Paul will be looking at the Descarte cohort, which allows us to see whether antibiotics prevent complications and re-consultations, along with the impact of delayed prescription, compared to an immediate prescription.
The Descarte study of over 13000 patients with acute sore throat showed that back up/delayed antibiotics should be considered as a first choice option for many sore throats when antibiotics are being considered as they prevent complications, reduce re-consultations and are at least as effective as immediate antibiotics.


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Bill Angeloni is the Founder & Director of Tenzing Consulting, a global management consulting firm he co-founded that now has over 850 experts and works with Fortune 1,000 clients and private equity. He started out at the Naval Academy, after which he served as an officer in the Navy for five years (while also earning his MBA from Northwestern's Kellogg School of Management). After his time on Active Duty, he worked at United Airlines doing strategy and operations work, was a Manager at AT Kearney, and a General Manager at FreeMarkets, Inc - a startup where he opened Europe and helped grow to $200M and then took public. After that, he co-founded his own Management Consulting firm, which he has co-led for seven of the last 15 years — he took an 8-year leave of absence to lead a tech company turn around, and start a couple other companies. He has worked with over 30 start-ups over his career and thinks of himself as a bit of a start-up junkie.
Why to Listen:
Bill has had an eclectic career and covers a lot of ground in this interview. In addition to talking about how to find and join a high-growth startup, he also talks about his experience starting his own consulting company. He also has fantastic advice about networking - how to approach it and why it's so important for veterans to learn how to do this effectively.


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|Montgomery County
|Code of Ordinances
|Part II. Local Laws, Ordinances, Resolutions, Etc.
|Chapter 52. Taxation.* [Note]
|Article I. General.
§ 52-18U. Reserved.
Latest version.
Editor's note—This Section has been reserved for legislation adopted by 2013 L.M.C., ch. 32, § 1, which will become effective July 1, 2014.
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Primary Resources
"The Long Journey Back to Humanity: Catholic Peacebuilding with Armed Actors"
Drawing on the peacebuilding experience of four Catholic peacebuilders in Colombia, northern Uganda, and the southern Philippines, this chapter by a leading practitioner-scholar of peacebuilding examines what is distinctive about Catholic approaches to engaging armed actors, both governments and rebels.
"NGOs and Conflict Resolution"
Access your institution's library to read Bartoli's article "NGOs and Conflict Resolution." It explores one important role NGOs play in conflict resolution: direct mediation in peace processes. It focuses on lessons learned from the work of four NGOs: the Community of Sant'Egidio, a lay Catholic community in Rome best known for its role in the 1992 peace accord in Mozambique; the Carter Center; the Center for Humanitarian Dialogue; and the Crisis Management Initiative.
Tom Bamat on CRS Catholic peacebuilding on extractives, Sudan, University engagement
"Peacebuilding in Praxis: Lessons from Africa: CRS Peacebuilding in Sudan"
John Ashworth, Catholic Relief Services. The video of John's talk begins at the opening and concludes at 21 minutes and 19 seconds. His presentation was at Catholic University in April 2013 as part of the Pacem inTerris at 50 conference.
This conference was intended to be one of the principal commemorations of the Pacem in terris anniversary in the United States. The conference examined the ways in which Pacem in terris is a living document that remains fresh today. It also helped animate peacebuilding as a priority for the Catholic Church in the United States and focused attention on ways in which Catholic perspectives on peacebuilding can contribute to the wider debate on the responsibilities and opportunities for peacebuilding in U.S. foreign policy.
"And They Shall Make War No More"
This paper describes the background to the last fifty years of violence in Columbia and identifies its causes in inequality, poverty and displacement. It then explores the ways in which the Catholic Church has been prominent in developing processes of peace-building that include "accompaniment" of the victims to include them in structures of citizen participation. It ends with theological and pastoral reflections on how this can be enabled practically in the Columbian context.
Africa Rising
In "Africa Rising", the statement "Reconciliation was Jesus' central mission. As his followers, it is ours." reflects comments from John Katunga (a member of the Catholic Peacebuilding Network) on the state of affairs in South Sudan and D.R.C. Author: Maryann Cusimano Love. Source: America, May 6, 2011, p. 10.


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We need to take trips when we want to take breaks from work or even avoid monotony. Everyone wants their trip to be exciting. However, trips do not turn out successful and exciting. They sometimes make you feel wasted for spending and not having fun or enjoying. There are tips to change these experiences. The tips are essential as they will help you have new exciting moments all the time you set out for a trip either alone or with some company. Travelers have the fears of going places and not having an adventure they expected. You are therefore not alone.
Set a Date
You have to take a time to set a day and a schedule for the trip. You do not just say that you will have a trip. If you have not set a date, the chances are that the trip may not be there at all. Make it real. Select that day that you are from work and other duties. Take a date that will turn out convenient for you to be out.
Save Enough Money before you Go
The worst experience in your trip is running out of cash. Save enough to take you through the trip period. If possible, have an extra amount from the budget you have to the plan. You need to splurge sometimes. It is time to have fun and adventure. You will, therefore, need a little treatment for yourself or your partner or children during the trip.
Have a unique experience in the trip by using luxurious services and rides. Have enough money so that your experience will be an exception and worth talking about in the presence of friends. Do not miss anything.
Get a Good Camera and Take Photos
During the trip, it is time to have fun. Carry with you a functional camera for photos. Memories of these times are good for you if you need to share with friends on how exceptional and exciting the trip was to you. They will need to watch the photos and pictures. It's weird to go to great places and scenarios especially beaches and games parks and not have photos to show. You can even share these photos with all social media friends. Memories from the photos remind you of good experiences.
Have Good Company
Trip time is the fun time, and it is advisable to go with friends or family members with whom you will have fun. You can go with a partner or spouse. You can also go with family members. If you organize the trip, ensure to provide gifts for your clue. Organize activities that make all happy. Above everything, go with someone who will not limit the extent of you having fun.
Do Some Planning before hand
Planning for most aspects of the trip before leaving your house is essential. Ensure you have all the travel information. It is impossible to plan for all the activities as you need to have fun and this will constitute of surprising yourself or having someone else surprising you. Plan of the cities and places you will need to visit. The time you will be on the trip is essential to plan for as you do not want to take the trip too far. Plan for things and equipment you are going to need or require in the trip. Inform those who need to know that you will be away to avoid destructions during your trip.
Make Local Friends
When you travel for the trip, make friends with the local people. This is essential in helping you enjoy the trip. It's a good dimension in your trip as local people can answer your questions and offer assistance if necessary. If you were on a lone trip, you can have drinks or catch movies with the friends. Try making a new friend daily.
Control Your Drinking
During the trip, do not get too much drunk. You need to be sober as you are in a new place and need to take care of yourself. If you drink too much, carelessness may come in, and you can lose your property or even get robbed. Getting too much drinking can make you oversleep and therefore destroy or alter your schedule.
Get Travel Insurance
Do not leave your home without the insurance. Also, ensure that your family has your travel information. We do not know about the future because anything can happen.
Make it Unforgettable
Since it may be one time visit to a place, have fun. Travelling gives you some freedom. Share experiences with new friends and go to the beach. If you are single, you can go on a date. Do something that will keep the memories of the trip alive
In other words…. enjoy your trip, you require making choices and remaining orderly. Have fun but be responsible. It is also good and vital to ensure you remain safe. Keep in touch with family or spouse while away. Be creative and find ways of having the adventure and having fun.


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Ahhhhh Monday you always come too soon, too soon! Morning routines….got one? Here's mine!
My Blackberry Zen chimes every weekday morning at 5:30. After a couple of (well-deserved) snoozes, I arise….
Ahhhhh Monday you always come too soon, too soon! Morning routines….got one? Here's mine!
My Blackberry Zen chimes every weekday morning at 5:30. After a couple of (well-deserved) snoozes, I arise….
One of the main things on my 'to-do' list today was to get a new eyeshadow primer. My current fave, Naked Beauty by Smashbox was sold out at my local Shopper's Drug Mart. I had every intention of trekking to Sephora to get a new one. That is, until I decided to organize my makeup bags, and YES I said BAGS (plural).
Well of course, I have figured out that I have a lot of makeup-and it's great stuff! I have selected the everyday products that I use for work. It was a lot more than I thought! Take a peek-I have numbered it all and will talk about it that way!
Hey everybody gets hungry right? Even me! I have walked by this place 123425456976 times of course but have never stopped in! This morning, Chi-Ko-Roo won the draw (or the rock-paper-scissors, whichever you fancy). Did some quick Internet researching for reviews (this place doesn't have a website) and was a bit skeptical. Wanting to be true to my 'I'll try anything once' mentality, I took the risk.
Here's the inside…..after arriving just past 10am:
Not too shabby, right? Perhaps because this is a former Il Fornello? Whatever the case, our friendly (and foreign) waiter, quickly brought 2 cups of coffee (smart man) and took our order. The food came 5 minutes later, and yes I time those types of things! This may be due to myself and beau being the only people there-but awesome nonetheless!
Here is the food:
Great food….quick service, and a fancy fruit shish to finish it off! Sounds good to me! Normally, a Sunday morning (or late morning meal) includes several mimosas but since I have training with George this afternoon (you will meet him soon), I decided against that….
Yes I will return to Chi-Ko-Roo!
p.s. If you are admiring my manicure (and you should be), you can thank Nails by Natalie. You will meet her soon too!
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The candle version of the sweet and delicious fragrance, created for Papier d'Arménie by perfumer Francis Kurkdjian. This beautifully understated soy and beeswax wax candle is poured into a frosted glass votive and invokes the heady scent of roses from Tunisia and Iran.
- Handmade in France
- Scent - delicately sweet, heady rose
- Eco soy and beeswax
- Approx 40 hours burn time
- View our full candle collection
- Never leave a burning candle unattended
Add some subtle warmth, light and joy to your space and create a gentle atmosphere of well-being to any room.
The Papier d'Arménie® candles were designed by Francis Kurkdjian. Environmentally sound, they are made from 100% vegetable (soy) and beeswax with a cotton wick and will burn for around 40 hours.
Burning advice - before first burning wick has to be cut to 1cm, once lit let the candle burn until most of the surface is liquid.
Cut the wick 1cm short before each burn.
Burn the candle no longer than 3-4 hours at a time under supervision.
Keep out of draft and reach of children.
Armenian paper is a type of incense that has been produced for centuries. Originally made from Benzoin Resin from an Armenian tree. Now available in three scents, the paper is infused with essences, fragrances or essential oils in order to achieve a perfuming or cleansing effect.
DESCRIPTION ABOUT REVIEWS Pure English beeswax stubby candles. Hand-dipped in natural golden tones with a subtle honey scent. These beautiful candles will glow and fill your room with the warming sweet...
DESCRIPTION ABOUT REVIEWS Pure English beeswax dinner candles. Hand-dipped in natural golden tones with a subtle honey scent. These beautiful candles will glow and fill your dining setting with the warming...
DESCRIPTION ABOUT REVIEWS These tall hand rolled natural beeswax dinner candles have a divinely honeyed smell and as they drip and burn, layers of texture and wax form which creates...
DESCRIPTION ABOUT REVIEWS Queen Idia Candle - with base notes of geranium and frankincense, top notes of lavender, hibiscus and the fragrance of soft African Moss. The inspiration for this...


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Bulking steroids in UK
Bulking steroids in UK are considered as the most preferred anabolic steroids in the whole world because almost all the body builders and performance enhancers have stacking muscle as one of the their major concern. Clearly speaking, the bulking steroids can be stacked with almost all the anabolic androgenic steroid but some particular anabolic steroids are found to be highly effective in this regard. There are some other bulking steroids that are equally effective in the cutting cycles as well due to the versatility in their nature. If you are looking to take any bulking steroid then you must keep some things in your mind. The first and the most important thing is that you must have complete understanding about what you are looking for. It is not that simple. After getting the complete understanding then you must think about your goal, whether you are willing to become a dedicated gym goer or highly competitive body builder who wants to build a lot of mass. Whatever the goals are, bulking steroids sold in UK will work in the same way for everyone. The difference would be due to the dose that you are taking and the food that you would intake. Those individuals who are willing to get mild boost while they are off-season then for them this article is not suitable because this article completely focuses on the genuine bulking steroids in UK.
What should you look for when buying Bulking Steroids Online in UK?
When the individual is looking to buy some steroids in UK to bulk up the body, the main concern for them is to add the size. But adding the size does not mean that you should entirely ignore the quality of your gains. The gains must be of quality otherwise they would not be long lasting. There is a misconception that the increase in strength and weight gain means that the size is also increased. For example, Halotestin is one of the few steroids that can help the individual in gaining strength drastically. However this increase in strength would not add the size or help you in bulking up. Another example can be of other steroids that can help in retaining very large amount of water in the body and if you are taking calorie rich diet then a large number of pounds would be added to your weight but the amount of quality gains would be zero. This sounds extremely simple but the fact is that very few people understand this and you can see in almost every gym.
A simple yet helpful example of above mentioned problem is being given. Assume that you are taking one of the best bulking steroids that is available in the whole world and within few weeks your weight increases drastically by 20 to 30 pounds. This is not impossible if you stack bulking steroid with Dianabol or Anadrol and take calorie rich diet. Many individuals find that their weight is increased so is their strength and they would scream happily that they have gained some quality muscles. But in reality they have not gained some muscles but there is excess water in their body which can leave the body within few weeks. It takes years for even a professional steroid user to gain 20 pounds of lean muscles. Increase in weight or strength should not be used as an indicator of measuring how much you have gained. The only indicator is the mirror. You should look in the mirror and see how much bulky you are looking.
The best Bulking Steroids on UK market
Whenever you are willing to buy any bulking steroid in UK you would evidently look for gaining some quality muscle mass for long term in the efficient way. Apart from quality gain you would obviously want to stay safe after using any steroids because almost every steroid has some side effects associated with them. Testosterone is considered as one of the effective and highly preferable steroid for the bulking cycle. It is one of the well tolerated steroid among UK adults. The effectiveness of the testosterone remains same regardless of the form in which you are consuming it. A list of bulking steroids in UK is being shared which we consider are the finest bulking steroids after reading the reviews of multiple users.
Above mentioned are the best steroids for the bulking cycle in UK and there are some other steroids as well that can be very effective in off season period. Equipoise and Winstrol are some other steroids that are very effective in the bulking cycle but if you are willing to get quality gains then you must use the steroids mentioned in the list.


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Eric Saintonge is my gymnastics coach. He has been helping me develop a stronger acrobatic base to make me more competitive in the world of contemporary circus. But, Eric's experience and background goes far beyond front handsprings…
After spending six of his late adolescent years on the National Gymnastics Team, Eric went on to perform for companies such as Cirque du Soleil and Cirque Eloize. It was through the touring production of Nomade with Cirque Eloize, that Eric was introduced to a new discipline the Cyr Wheel.
Now, Eric tours his own Solo Cyr act at many special events throughout North America, and is a sought after personal trainer. Oh, and did I mention… he's also a family man, and proud father of 2!
Here's a little bit more about Eric:
Gymnastics was your life for many years. When Cirque du Soleil came "knocking on your door" what was the biggest reason that you left gymnastics and joined the company?
"At first I didn't care about circus. I kind of a had condescending feeling towards it. I was good at school and wanted to become an engineer. Didn't want to have clown written in my resume!
But then one of my ex-coach made the move to Cirque du Soleil and I saw him a few years later when Saltimbanco was in town (1995?) it's then that he made me realize that becoming a circus artist would be a great continuity to what I've had been doing for the last 16 years. He said: "In the circus you will do what you good at". That had me thinking…no pommel horse, and I would be paid for doing stuff that I like to do?
One thing led to another, and the research and development team called me to do acrobatic research on an apparatus that they built, or would be building.
That was it, my foot was in the door, and the door hasn't close for the last 18 years!"
Having a family is a big part of your life, but I'm sure continuing your career as a freelance artist, and now a personal trainer hasn't always been easy. How do you strike a balance between career and family life?
"As a freelance circus artist, I had to make choices. I try to not take long contracts that would have me gone for long periods of time. There is a big market in Europe, especially in Germany, for diner shows. Diner show is a theatre where you can go for dinner and while you eat or between services there's circus act and all this is link together with an MC. The problem with this kind of contract is that they last between 3 months to a year, which is why I decided not to do them. As long as the contract last no more than 10 days to 2 weeks I'm usually fine (my wife as well, she has to take care of the kids!!) with it. As a matter of fact, as I'm writing this I'm a week away from an 11 days contract in Dubai!
As a personally trainer I can manage my appointments according to my children's school and daycare schedule, and my wife (also a former circus artist) work schedule as well. It's a matter of logistics!"
You traveled for a long time with some pretty big circus companies. What would you say it the biggest thing you were able to take away from your experience of being on the road as a circus artist?
" I learn't to take care of myself! That might sound weird, but when I left on tour with Alegria in 1997, I had never been in my own apartment. I was living with my parents until the departure.
I also learnt that wherever you are in the world, and whomever you meet, at the end of the day we are all the same! We are all humans and all have more or less the same daily problems and enjoyments.
I've traveled to small villages in Palestine, as well as performed in big cities like Paris, Sydney, Berlin…. No matter where you are kids will always play in the park!"
Now that you are performing and producing your own solo act, what would you say are the benefits to self-producing, versus working for a big circus company?
"Simply put, self-producing means that I am my own boss. I decide when I train, how I train, and generally get a higher pay."
You've achieved so much already in terms of a career in circus. What is you next big goal, and why is it important to you?
"I'm slowly moving towards more and more to personal training. However, I don't want to be a regular personal trainer. I want to help people change their life.
I have recently become a certified CHEK Exercise Coach. This course really was life changing. The approach taught by Paul Chek is an integrative approach. We look at an individual from different perspectives; nutrition, digestion, sleep, spiritual, emotional and gather all of the information and use it to create an optimize training program for this individual.
This means I won't write them a program in 5 minutes. I go through the process of assessments (flexibility, posture, muscular, nutrition, sleep/wake cycle, digestion, stress)."
Here's a clip of a Eric teaching push-up techniques for Cirque du Soleil!
If you could learn any other discipline in Circus what would it be?
"I would love to try the Wheel of Death! It looks amazing. You must get such a huge adrenaline rush doing it. But the name of it says it all…You could die! So would love to try it without dying!!
Trampo-wall is something that I wish existed when I first started to do circus. It's an amazing discipline that is beautiful to watch. I think I could have been good at it."
I know you are an avid follower of the "Paloe" diet… what would you say is your favorite Paleo treat?
"I love a nice juicy steak with tons of raw and cooked vegetables. One of my favorite breakfasts is veal liver with bacon, raw vegetables (peppers, cucumbers, carrots) and avocado. (sounds delicious) A nice sweet treat is an apple with almond butter."
If you would like to know more about Eric, feel free to visit his website.
For more information on Paul Chek and the Chek certification visit: www.chekinstitute.com


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- science news Liquid drop of DNA libraries reveals total genome information
October 22
Unlike the tightly controlled replication of DNA in living cells, PCR amplification, a "workhorse" of molecular biology, balances between simplicity and accuracy. Conventional "bulk" PCR often yields inefficient and nonuniform amplification of complex templates in DNA libraries, introducing unwanted biases.
- science news Discovery of the novel protein encoded in mammalian mitochondrial DNA polymerase gene POLG
September 25
Researchers from Laboratory of bioinformatics approaches in combinatorial chemistry and biology and Laboratory of high-performance screening of biological objects together with colleagues from Moscow State University and University College Cork (Ireland) discovered novel protein POLGARF, which is encoded in alternative reading frame of mitochondrial DNA polymerase POLG mRNA. The results of this study are published in PNAS.
- science news Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers
September 10
The scientists from the Laboratory of biocatalysis, the Laboratory of proteolytic enzyme chemistry, the Laboratory of bioinformatics approaches in combinatorial chemistry and biology and the Laboratory of hormonal regulation proteins, together with colleagues from EMBL-Hamburg, Moscow State University. M.V. Lomonosov, the Sheffield Institute and the Scripps Research Institute have developed a universal algorithm that makes it possible to create biological antidotes based on biocatalysts, directionally increasing their reactivity, and to predict stereoselectivity.
- science news The discovery of four genes of the Noggin family in lampreys is consistent with the hypothesis of two rounds of genomic duplications in vertebrate ancestors
September 10
Researchers from the Laboratory of Molecular Bases of Embryogenesis, together with a colleague from the Severtsov Institute of Ecology and Evolution, described for the first time four genes of the Noggin family in the oldest representatives of vertebrates - lampreys, and compared their structure, expression and some functional features with those of the known genes of this family in other vertebrates.
- science news A versatile platform for bioimaging based on colominic acid-decorated upconversion nanoparticles
September 3
Scientists from the IBCh RAS, Federal Scientific Research Centre "Crystallography and Photonics", FSBSI "N.N. Blokhin Russian Cancer Research Center", Lomonosov Moscow State University of Fine Chemical Technologies and Sechenov First Moscow State Medical University developed a method for the UCNP surface functionalization with endogenous colominic acid conferring "stealth" properties, which led to effective accumulation in the area of inflammation, as well as micro- and macro-blood vessels visualization.
- science news Toxin from black mamba venom inhibits growth of glioma cells selectively expressing ASIC1a channels
July 20
Gliomas are fast growing and highly invasive brain tumors, characterized by tumor microenvironment acidification that drives glioma cell growth and migration. Channels containing Acid-sensing Ion Channel 1a subunit (ASIC1a) mediate amiloride-sensitive cation influx in late stage glioma cells, but not in normal astrocytes. Thus, selective targeting of ASIC1a can be a perspective strategy for glioma treatment.
- science news Start codon context and occurrence of AUG codons in the beginning of protein coding open reading frames co-evolve
July 17
Researchers from IBCh RAS together with their international collаborators discovered an evolutionary link between efficiency of start codons and the probability of AUG codon occurrence in the 5'-end parts of protein-coding sequences. When start codons are inefficient the next AUG codon is more likely to be found in the same reading frame. At the same time in case of highly efficient start codons, the next AUG codon is more likely to be found in alternative frames. They also have shown that weak initiation at the first starts is associated with the synthesis of shortened proteoforms as a result of initiation at the second starts.
- science news New technology promises to revolutionize nanomedicine
July 16
A collaboration of scientists from the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, the Moscow Institute of Physics and Technology and Prokhorov General Physics Institute of the Russian Academy of Sciences have developed a breakthrough technology to resolve a key problem that has prevented the introduction of novel drugs into clinical practice for decades. The study was published in Nature Biomedical Engineering and featured in the journal's News & Views section.
- science news A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding
June 26
Kinase-mediated phosphorylation represents one of the general strategies for the emergence of antibiotic resistance. A new subfamily of AmiN-like kinases, isolated from the Siberian bear microbiome, inactivates antibiotic amicoumacin by phosphorylation. The nanomolar substrate affinity defines AmiN as a phosphotransferase with a unique catalytic efficiency proximal to the diffusion limit. Crystallographic analysis and multiscale simulations revealed a catalytically perfect mechanism providing phosphorylation exclusively in the case of a closed active site that counteracts substrate promiscuity. AmiN kinase is a member of the previously unknown subfamily representing the first evidence of a specialized phosphotransferase bioscavenger.
- science news Transgenic aspen plants (Populus tremula) with the expression of recombinant xyloglucanase sp-Xeg show an increased growth rate, altered composition and properties of wood, and the phenotype of the plant as a whole
June 8
Scientists from the Group of Forest Biotechnology IBCh RAS obtained the transgenic aspen with acceletated growth, a modified carbohydrate composition and a slower rate of decomposition of wood.
- conferences Lipids 2021 Conference
October 19–21, 2021
Lipids 2021 Conference, October 19-21, 2021, IBCH RAS, Moscow
- science news Lecture by Director-General of the ICGEB Lawrence Banks «Human Papillomaviruses: From Infectious Entry to Malignancy»
January 27 (This event is over)
ICGEB Director-General Group Leader Lawrence Banks will deliver a lecture entitled «Human Papillomaviruses: From Infectious Entry to Malignancy». Date and time: Mon 27 January 2020 14:00. Location: Small conference hall at 3rd floor BON IBCh.
- science news LIGHTS ON: Molecular Imaging of disease dynamics in vivo
September 27 October 11, 2019 (This event is over)
Abhijit De PhD Scientific Officer 'F' and Principal Investigator Head, Molecular Functional Imaging Lab Advanced Centre of Training Research and Education in Cancer, Tata Memorial Centre, Kharghar, Navi Mumbai, India.
- science news Seminar "Molecular Brain": Anton Maximov
October 8, 2019 (This event is over)
The seminar will be held on the 8th of October at 3 pm in the Small lecture hall (3rd floor, BON, IBCh). Everyone is welcome!
- conferences II Joint Life Sciences Forum: VI Russian Congress on Biochemistry and IX Russian Symposium «Proteins and Peptides»
October 1–6, 2019 (This event is over)
Dear Colleagues! We are pleasure to invite you to participate the VI Russian Congress on Biochemistry, which will be held in Sochi, Russia (Dagomys Hotel) on October 1-6, 2019.
- science news Lecture by Prof. Yibo Wang «Drug Discovery Targeting Transmembrane Protein-Protein Interactions»
August 26, 2019 (This event is over)
Prof. Yibo Wang from the Changchun Institute of Applied Chemistry will deliver a lecture entitled «Drug Discovery Targeting Transmembrane Protein-Protein Interactions». Date and time: Mon 26 August 2019 11:30. Location: Conference hall at 5th floor BON IBCh.
- conferences 12th INTERNATIONAL CONFERENCE "BIOCATALYSIS.FUNDAMENTALS & APPLICATIONS" "BIOCATALYSIS-2019"
June 24–28, 2019 (This event is over)
Dear colleagues, The Lomonosov Moscow State University and RAS institutes, including IBCH RAS, is planning to convene a traditional biannual 12 th International Conference "BIOCATALYSIS-2019" in June, 24–28, 2019. Conference will be convened on board a ship cruising via the route St. Petersburg – Valaam – Kizhi – St. Petersburg. More info is available at http://bc2019.org/.
- science news Scientific School for young scientists «Structural biology: main problems and approaches to their solution»
June 6, 2019 (This event is over)
Dear colleagues! The Scientific School is devoted to the latest achievements and methods in the field of structural research will be held at the IBCh RAS on Thursday, 6 June 2019. The scientific program of the School includes lectures by leading scientists working in various fields of molecular biology and representing the basic structural methods, namely, X-ray Crystallography, Cryo-Electron Microscopy, NMR-spectroscopy and computer modeling.
- science news "Molecular Brain" seminar
April 16, 2019 (This event is over)
The seminar is timed to the birthday of academician Eugene Grishin and will take place on April 16 at 14:00 in the Hall of Academic Council. Members of the Department of Molecular Neurobiology created by Eugene, will give talks on their present work. Everyone is cordially invited.
- science news Microscopic Imaging of Epigenetic Landscape - A Universal Platform to Study Epigenetic Changes at Single Cell Level
February 15, 2019 (This event is over)


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Koh Samui
Mandalay Beach Villas
By Magaly • Jul 30, 2013 • Selected Work
Mandalay Beach Villas are a compound of vacation villas located in Koh Samui, Thailand.
The structure's elegance and sophistication is perfectly paired with the watercolor of its background: the clear sky, the calm sea, and the glittering sand.
Luxury W Retreat Koh Samui in Thailand Update
By Magaly • May 27, 2013 • Selected Work
Celadon Villa in Koh Samui, Thailand
By Magaly • Jan 23, 2013 • Selected Work
Celadon Villa is located on the island of Koh Samui, off the coast of Kra Isthmus, in Thailand.
Surrounded by lush vegetation and the view of the ocean and nearby islands, the villa provides guests with the perfect location for days and evenings full of luxurious relaxation.
Villa Belle in Koh Samui, Thailand
By Magaly • Jan 19, 2013 • Selected Work
Villa Belle is a luxurious villa in Choeng Mon Beach on the island of Koh Samui, Thailand.
Terraces and interiors are decorate with pieces illustrating the culture of the country, while providing utter comfort and relaxation for its guests.
Top 10 Infinity Pools Hilton Worldwide
By admin • Dec 12, 2012
Infinity pools are usually visually stunning and they are the most beautiful man-made pools in existence.
Here is a compilation of the world's best infinity pools from Hilton Worldwide, one of the largest hospitality companies in the world.


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Traditional Local Rum Experience
Here's a true Jamaican must-do: stopping at a roadside rum bar. Humble on the outside, these bars are fully stocked with many styles and flavours. So pull over, drop in, and raise a glass the way the locals do.
Insider tip: if you really want to blend in, ask for White Overproof.
You'll find these little rum bars along the roads all over Jamaica. Why not make your own tour and hit a few of them?
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HIMOTE HOUSE: A share house of super psychic girls – Anime Preview
Synopsis: The three Himote sisters, Tokiyo, Kinami, and Kokoro, are living in what they've dubbed the "Himote House" in Nakano, Tokyo. Sharing the house with them are their former classmates, Tae and Minamo, and a cat named Enishi. These five unique girls live a boisterous life at the Himote House, spending their days trying to figure out how to get guys to like them. What's more, the five of them, and the cat, all have a mysterious power… (Official Crunchyroll Synopsis)
1st Episode Review (Warning: Minor Spoilers to Follow):
The first thing that jumps out in Himote House is that the animation is ALLL CGI and not great CGI. That is to be expected considering this is just a short but it's a heavy strike against a show like Himote House, which simply does not have the comedy or content to make up for it. Himote House tries to be a show with cute and quirky girls but their personalities all feel wafer thin, generic or plain peculiar without rhyme or reason; such as the oldest girl/sister in the house speaking with a pseudo foreign accent but no explanation as to exactly why she speaks that way. It also draaags its jokes out; like this one scene where the girls spend several minutes just complimenting and commenting on each other's choices of underwear. It goes on so long that it quickly becomes boring, and it's worse when it didn't even start out that funny.
Himote House is probably entertaining if you watched it for ironic reasons, or fun for someone who is capable of overlooking the stilted CGI and wonky designs, and who also happens to have a penchant for slice of life anime with an all girl cast. But the comedy is so weak that I feel it would really require complete and utter devotion to the cast and their 'cuteness' to be able to find any of the jokes amusing. And least we forget, YES! the girls have super powers and just like the random quirky personalities and events that occur in the first episode, the powers pop up just as randomly. Not only that, our up to now non powered heroine suddenly and easily discovers her own psychic power just by 'trying' it. Oh.. and there's a talking cat because, why not? We've already thrown in as many random and sudden elements as possible so what's one more? If you've been extremely starved for a really 'random' short comedy anime featuring a gaggle of girls, maaaaybe try Himote House but go in with the lowest of low expectations.
HIMOTE HOUSE is available for streaming via Crunchyroll.


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Tag Archives: health
Evidence: Trayvon Martin was at 7-11 buying chems for home made drug cocktail
It is amazing how the elite media hid this for so long, but as Winston Churchill said, "A lie gets half way around the world before the truth can get its pants on". Lean – it is a street drug … Continue reading
Posted in Editorial, Elite Media, Gangsta Govt, Lies Tagged current-events, health, medicine, politics, society 1 Comment
Erin Morgart's Washington Examiner Interview
This writer s very fortunate to be friends with three of the most successful and beautiful fitness trainers in the world, Lori Hendry (pic), Christine Lakatos (pic), and Erin Morgart (pic). They are all brilliant, traditional in their point of … Continue reading
Posted in Culture War Tagged christine lakatos, fittv, health, mental-health, political circles, workout partner Leave a comment
Five-Point Action Plan for President Obama to Reduce Violence by the Mentally Ill
By our new friend D. J. Jaffe. [Editor's Note: D. J. Jaffe maintains a list of links and information about mental health policy. His work is a must read for anyone interested in public safety.] President Obama said the federal … Continue reading
Posted in Firearms, True Talking Points Tagged government, health, medicine, mental-health, politics, research Leave a comment
Canadian health care rationing 'a crisis for Quebec women'
Montreal Gazette: MONTREAL — Surgery wait times for deadly ovarian, cervical and breast cancers in Quebec are three times longer than government benchmarks, leading some desperate patients to shop around for an operating room. But that's a waste of time, … Continue reading
Posted in Health Law Tagged health, mcgill university health, medicine, mental-health, research, science Leave a comment
83% of American physicians have considered leaving the profession over ObamaCare
This is up from 2010 where two polls showed that 45% of doctors would quit taking government insurance if ObamaCare was enacted. Newsmax: Eighty-three percent of American physicians have considered leaving the profession over President Barack Obama's healthcare reform law … Continue reading
Posted in 2012 Primary, Econ, Health Law, Obama, True Talking Points Tagged climate, government, health, medicine, politics, science 1 Comment
British Socialized Health Service Kills Off 130,000 Elderly Every Year
And Obama tried to appoint Don Berwick as a senior HHS official who believed that the British socialized rationed system was "the" model. UK Daily Mail: The NHS kills off 130,000 elderly patients every year Professor says doctors use 'death … Continue reading
Posted in Europe, Health Law, Obama, True Talking Points Tagged care pathway, health, medicine, mental-health, nhs doctors, terminally ill patients 1 Comment
Why Are Health Insurance Premiums Increasing Faster After ObamaCare Passed?
This is one of those MUST read posts that must be read from beginning to end to have the necessary impact. Read every last word. Normally we try to excerpt posts, but this information is SO important that as many … Continue reading
Posted in Health Law, Obama, True Talking Points Tagged current-events, health, medicine, research, science Leave a comment
Priceless: Pro-Socialized Health Care Supporter Runs Into America's Foremost Expert On Obamacare (video)
Our friends at iowntheworld.com have a delicious post with (full disclosure) my good friend Steven Tucker affording the most awesome schooling to a rather surprisingly open minded young leftist on ObamaCare. Tucker is one of America's foremost experts on health … Continue reading
Posted in 2012 Primary, Health Law, Obama, True Talking Points Tagged current-events, health, medicine, politics, vacation 1 Comment
Sentenced to death for being old: British NHS denies life-saving treatment to 78 year old
UK Daily Mail: When Kenneth Warden was diagnosed with terminal bladder cancer, his hospital consultant sent him home to die, ruling that at 78 he was too old to treat. Even the palliative surgery or chemotherapy that could have eased … Continue reading
Posted in 2012 Primary, Health Law, Obama, True Talking Points Tagged health, medicine Leave a comment
60% of Doctors say ObamaCare will have a negative impact on overall patient care
Heritage: The American public doesn't support Obamacare, and a new survey shows that doctors have an even worse opinion. No one has a better grasp on the state of the health care system than physicians, and according to the Doctors … Continue reading
Posted in 2012 Primary, Health Law, Obama, True Talking Points Tagged government, health, medicine, mental-health, research, science Leave a comment
Secret Video: Healthcare in China
A friend, novelist Steven C. Bradley is in China. He had an accident while working out and injured his wrist so he want to the local hospital to make sure he was alright. It is forbidden to take pictures in the hospital … Continue reading
Posted in China, Health Law, Obama, True Talking Points Tagged health, medicine Leave a comment
Sandra Fluke: Catholic Institutions Should Pay for My Sex Change!
Sandra Fluke demanded in her testimony to Congress that Catholic Universities, Hospitals and other institutions give her $3,000 worth of birth control because she goes to school at Georgetown (Catholic) University which is enough to buy so many condoms that … Continue reading
Posted in 2012 Primary, Culture War, Education, Health Law, Obama, School Indoctrination, True Talking Points Tagged current-events, health, politics, religion Leave a comment


text: Ice can destroy a tree. Water can drown a person. These two may need to swim to work. H2O can be a benefit to our lives in so many ways. If you are not careful with it you will be sorry. We sometimes forget to respect the elements that God has put here for our well being. God has given us laws to guide us in dealing with nature. We have meteorology that helps us to know what is coming so we can be properly prepared. We have the Bible that teaches us what is coming and how to be prepared. Preachers are trying to warn us to be ready at any time for changes. Are you listening? Will you be like a person that did not listen to the news and gets caught unaware when a disaster strikes? I am listening Jesus help me to help others prepare for what is right around the corner!


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Miss Galaxy-UK, Emma Collingridge, was invited to model in a charity fashion show!
Emma Collingridge, Miss Galaxy-UK, was invited to model in a charity fashion show!
The fashion show was in aid of Colchester & Ipswich Hospitals charity – Blossom Appeal. The Blossom Appeal is fundraising to build a new breast care centre at Emma's Local Hospital.
Emma loved being a part of this special evening to support a local appeal and had such a wonderful time!
Great work, Emma!


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Accountability Health Check
I'm weak in this place! The food here is insanely! As much as my husband keeps say ing WE needs to eat better…I really am eating just fine and have been. Speak for yourself buddy! My portions have been less, the type of food I eat at less 6 days most of the week are very good for my body and not full of preservatives and other junk.
New Jersey is full of beautiful food! The newest food I have discovered, is the New Jersey bagel and cream cheese. I would like state that these bagels are like nothing I have eaten before! I have had plenty bagels before and they are pure junk! You other states should be ashamed of yourselves. All these hard thick spongy bricks and that processed cream cheese! I thought that was all there was… that was until now!
New Jersey, you have changed the game! YUM!
So guilt is on the menu again. My stomach will hate me and I know better. I have this thing about wanting to eat food that taste really good… like bread. I am still eating plenty of veggies but have stopped eating so much fruit since these dang bagels. seriously, does it even matter? At least it's real food!
I am still making sure to get my workouts in daily Monday through Friday, nothing has changed there. Yet, somehow I feel fatter? Maybe it's the bagels? I know this week in general my activity level is the lowest is has been in awhile because my daughter has been homesick with a bad cold and high fever.
My walks have been shorter, my outside time has been cut down to less than half of what I do normally. However, my steps up and down the stairs are twice as much but it's not the same.
Hopefully next week, my last health check post, I'll have some good results.
Mental Health check
This is one place I really have to be care with because everyone, I feel is watching one place too.
I do think I am doing good and my anxiety is settling down. Some frustration comes up every now and then because communication is a struggle for me with my husband and because I'm the one with anxiety- it must be me with the communication problem as well. It couldn't possibly be both of us and even…him??? It's hard to live with the world's most perfect human. But somehow I do it. Was that sarcasm? Maybe.
Anyway, I had my second appointment with my counselor/life-coach and I did manage to meet everything on our first action plan. She does want me to get a savings of my own at some point but I'm nervous still about how to go about that. Baby steps.
Others things, I'm doing is writing down 5 things that I'm thankful for everyday and I started a marriage devotional/Bible study on Thursday. I got connected to my daughter's PTA at her school, this will meet people and I need that!
Mentally and emotionally, I'm doing good…Sure, I have some tearful moments but they are triggered by people being hard and inflexible or just plain mean, not situations so much anymore. I'll get pass them just like I do everything else. I'm stronger everyday.


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|2—6 players
|Age restriction 12+
|60 min. to complete
|350 Kn per team
Step into the place where nothing is as it seems. What looks like an ordinary office of an old professor, may turn out to be a cryptic chamber filled with mystery. Discover the secret every scientist has been searching for and many might be ready to die for. But be careful, you have 60 minutes to escape or the secret will stay hidden from you FOREVER!
This was my first game ever, so it has that special place :) That aside I think this is a great beginers room. It's not that difficult, but it's definitely not that simple as well. We had a great time at Labirintanje and I can't wait for the new rooms to open :D


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Ever see a gorgeous container garden with azaleas and other plants? A container garden can beautify any part of your garden. It is not hard to do! Follow these basics, and you can have a lovely garden, even if you have poor soil or no soil at all!
Tip: If you are going to combine your Encore with other plants in the same pot, choose plants with similar soil, water, and light requirements. However, you can combine plants with different soil or water requirements by putting smaller plants in separate pots, then sinking them in the soil around the azalea. It is also easy to pull these plants out and exchange them for new ones if you use separate pots.
For more garden ideas, click here.
To browse the full Encore Azalea Collection, click here.