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About Ohm is Futile
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Scott Manley reference while loading?
Ohm is Futile replied to PaperAviator's topic in KSP Discussion"Fly safe" is a very common thing to say in Eve online, which Scott has played. Maybe they were thinking of Scott when they put that in, but it's largely used by certain communities, which do not include our good friend Scott Manley.
Parachute-only Duna landing
Ohm is Futile replied to Foxster's question in Gameplay Questions and TutorialsThis. Very much this. Also very much this. Note that parachutes will gain effectiveness if you have an engineer to repack them and attempt multiple landings with the same lander. For a single landing and then back to Kerbin, a couple of drogues can help a lot (depending on mass, ofc) and you should otherwise not worry too much about fuel expenditure for the landing.
Minimum vertical speed for ascent?
Ohm is Futile replied to The Aziz's question in Gameplay Questions and TutorialsGood advice. Quick note, you don't need the maneuver node at AP if you have KER. You can have it display that information on the fly with perfect accuracy at all times.
Low-Tech Aerobraking?
Ohm is Futile replied to Casualnaut's question in Gameplay Questions and TutorialsAerobraking maneuvers are a difficult balancing act, typically. You want to go low enough to brake within an acceptable time frame (one pass for aerocapture) but not so low you burn up and/or crash. That altitude highly depends on the amount of drag your vehicle can generate and how much heat it can survive. That means you should really be wary of something having a lower max temperature than the rest of your ship and it not being in a service bay or protected somehow. If you plan on aerobraking, part temperature values are always worth looking at. Now, if you don't need a capture on the
Minimum vertical speed for ascent?
Ohm is Futile replied to The Aziz's question in Gameplay Questions and TutorialsI wouldn't bother with the exact numbers. It's not about the speed number or even the attitude at whatever altitude (although that's typically a decent indicator). It's about TWR. Rockets with more or less TWR will want a more or less aggressive gravity turn. Another decent indicator is time to apoapsis. If it's above 1 minute and rising, tilt more until it stabilizes around one minute. Keep that going 'till orbit or until you reach the desired apoapsis and then throttle down until you reach apoapsis and then circularize.
Low-Tech Aerobraking?
Ohm is Futile replied to Casualnaut's question in Gameplay Questions and TutorialsNo. Radiators are not meant to shed heat during atmospheric flight. If you want to aerobrake, use a heat shield, use airbrakes (depending on the context), use wings and control surfaces with sufficient heat tolerance, but do not use radiators.
Rovers (or Elsewise Moving Around) on Gilly?
Ohm is Futile replied to Srpadget's question in Gameplay Questions and TutorialsWell, there is a somewhat universal solution if you really want to go wheel. Depending on the size of the vehicle, it could be anywhere from crazy impractical to pretty trivial. Basically, you could put the smallest thrusters on your vehicle facing downwards and then muck around with thrust limits and throttle to see how much you need to stay on the ground... It shouldn't be too expensive in terms of fuel, at least for the very short trips you would be doing. That said, Gilly is probably just too small to apply even this. RCS and other lightweight solutions should be fine and probably mor
Can't gather data near Mun
Ohm is Futile replied to dylanh88's question in Gameplay Questions and TutorialsI just realized this but how many relays do you have? is it possible the relay itself is losing sight with the KSC? Because I ran the numbers in Poodmund's signal calculator and as long as all the antennae are deployed and one of the satellite has KSC connection, then you should at least have a red bar if not two orange ones. It definitely should not be completely disconnected.
Equations needed
Ohm is Futile replied to Pretorian28715's question in Gameplay Questions and TutorialsNot a bad guide, although it's pretty technical and the pictures are broken. I would think some googling should actually yield the answers. I'm sure some of my more technical fellows can answer in more detail, as for me, I can tell you you don't need those to go anywhere in the stock game. In fact, you may very well manage to do pretty much anything in the game without being aware of all the math involved. Blasphemy, I know.
Duna Mission: What's it take?
Ohm is Futile replied to grafdog1138's question in Gameplay Questions and TutorialsWell, Duna is close enough that you can pretty much throw something together as long as you respect some rules of thumb to make it strong enough. It will be over-engineered and more expensive than it needs, but it will do the job. That said, I am a sucker for tools such as dV calculators and launch window planners. Basically, anything that takes the guesswork out of the equation and I wouldn't say it's perfect for new players, but it can take a lot of frustration out of the process especially with interplanetary trips as those involve a lot more time both designing and flying. It also mak
Diagnosing my Satellite?
Ohm is Futile replied to Solis's question in Gameplay Questions and TutorialsPS4 version might be different enough. I just don't know at this point. From my test, this is not what happens, at least not with the original design. It was not perfectly stable, but it did not behave like something that wants to flip either. I was pretty sloppy and ended pointing the rocket well away from prograde in the lower atmosphere. I've wrestled a top-draggy design recently, and believe me, this one may not be perfect, but it actually wobbled back and forth because it wants to fly prograde much harder than it needs for a good gravity turn. Something flip-inclined would
Can't gather data near Mun
Ohm is Futile replied to dylanh88's question in Gameplay Questions and TutorialsYeah, only thing I can think of is that the HGs are not extended... Also, do you have any mods that could affect the strength of antennae? What about the difficulty settings?
Diagnosing my Satellite?
Ohm is Futile replied to Solis's question in Gameplay Questions and TutorialsOk, so I made this. It looks pretty much the same, it has a different value by 60 moneys, but as far as I can tell, the thing is otherwise a perfect replica from the OP. I got this into a 250km by 250km orbit with my eyes closed with 2,800 m/s dV left in the tanks. I ditched the middle stage a fair bit earlier due to the lack of torque because of the reliants, I would probably have significantly more fuel left if I used swivels. As I expected, the winglets prevented me from making a really nice gravity turn, which is why the orbit is so high. It flew a bit weird, but even with sloppy cont
Diagnosing my Satellite?
Ohm is Futile replied to Solis's question in Gameplay Questions and TutorialsHmm, food for thought... I mean, you are not talking about the winglets which were there initially (which I believe do more harm than good) which should counteract a significant amount of torque. At this point I'd be curious to recreate the rocket with and without the winglets and actually test the thing, because in my experience this rocket doesn't look too crazy in terms of top drag.
Diagnosing my Satellite?
Ohm is Futile replied to Solis's question in Gameplay Questions and TutorialsI tend to agree with that, but who knows? It depends on the target orbit for the satellite and a bunch of other factors. I strongly doubt that there is more drag at the front of the rocket, unless the service bay doors are open during the lower atmosphere part of the flight. If the doors are closed, there's no way the drag is higher at the top than the bottom with those winglets (not that I think they should be there, but that's another debate). The doors are closed during launch, right? Not a bad idea to incline the rocket on the launch pad, especially with the clamps. It'


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Kitchen Mitten (In-the-Hoop Project)
In this master class you will learn how to correctly embroider and sew this Kitchen Mitten.
Warning! This technique requires hoop 180x300 or larger!
Click on the picture to see an enlargement
Hoop one layer of tear-away stabilizer.
Print the files "mitten-shape-1.jpg", "mitten-shape-2.jpg", сut out the template.
Cover and slightly glue the stabilizer with a piece of padding polyester, batting, or any other filling.
Place the basic fabriq on top of it. Secure with pins, outside of the embroidery area.
Upload the file "mitten-1a" into your machine. Start embroidering.
Take the embroidery out of the hoop. Cover the embroidery with the template and with a pencil, trace the outlines of the thumb.
Cut away the detail with a seam allowance 1,5 cm. Press the embroidery.
Hoop one layer of tear-away stabilizer, cover the stabilizer with a piece of padding polyester, place the basic fabriq on top of it. Upload the file "mitten" into your machine. Start embroidering.
While do not embroider the last color of the design.
Take the hoop out of the machine.
Cover the embroidery with the first detail of the mitten face to face. Align outlines and pin the details together. Do not open the hoop and try not to displace the stabilizer.
Return the hoop to the machine and finish the embroidery. The machine will make the outline of the mitten and stop. Make sure the details are not shifted. With the help of scissors or large needle lightly press down the fabric in front stitch.
Take the embroidery out of the hoop. Stitch the details together along the outline of the thumb. Cut away the excess stabilizer and filling. Press embroidery.
While not turn the mitten out.
Cuts out of the lining fabric two details (use the same template). Reserve seam allowance at the top edge to outline mitten. Stitch. Place lining part of the mitten on the basic part and attach with hand stitches in several places along seams.
You can make a loop. Insert the loop between the parts lining before stitching.
Finish the top edge with the lining allowance.

subset: commoncrawl


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2020-2021 Southern Wake Academy Lottery
Thursday, February 27, 2020
SWA Gymnasium
Parents are welcome to attend, if desired. We expect the electronic running of the lotteries to take approximately 5 minutes. All entrants will receive an email with their student's lottery results. The email will come from firstname.lastname@example.com. PARENTS ARE RESPONSIBLE for checking email updates from Lotterease and responding within the given time frame.
|Slots Available
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~ Applications for the 2020-2021 school year are now open in Lotterease. ~
Please click here to register for the Southern Wake Academy Lottery and fill out a student application.
- Create an account with your name (parent/guardian)
- Register for the lottery
- Register your child
- Pick the Lottery Name (grade and correct school year)
- If there are siblings to enter, select "Add Sibling" on left side menu and repeat steps 3 & 4
SWA Application Process
Click here for the Admissions & Enrollment Policy
Our online application for the Lottery will be available beginning December 1, 2019 through 12:00 noon on February 27, 2020. The Lottery will be held on Thursday, February 27, 2020. Applications submitted following the Lottery will be placed on the wait-list for the grade to which applied. The number of slots available is currently set at 1 until such time that we determine the number of returning students and siblings. Once those numbers are established, closer to the lottery date, the number of available slots will be updated. (Please see below.)
Be sure to select the correct grade that your child will enter for the 2020-2021 school year. Grade selections may not be changed once a student has been selected in the lottery or from the wait-list. Only 1 (one) application per student is allowed. Multiple applications for the same student will result in disqualification and removal from the Lottery.
Lotterease Surname Option: The Surname option is based on the Charter School Lottery Laws of North Carolina. By default, the parent setting is set to 'Accept,' but parents may choose to 'Decline.'
If the parent accepts the Surname option, then only one application, the primary surname application, is entered into a school lottery per surname sibling type chosen. In this case, even though the parent may enter several surname siblings into a lottery, the last application that is submitted will be the primary surname application and will be the only one visible in the list of applications before a lottery is run. However, the parent will still see all sibling applications in their account. They can change which application is the primary surname application before the lottery is run. When the lottery is run, if the primary surname application is selected for admission, then the secondary surname applications will be given preference in the lottery. (Meaning they will move to the top of the waitlist.) On the other hand, if the primary surname application is waitlisted when the lottery is run, then the secondary surname applications will be placed at the bottom of the waitlist. After the lottery is run, surname siblings have the ranking of the Application Preference Group 'Applicant Siblings'.
If the parent declines the Surname option prior to the running of the lottery, then the surname siblings in that family are entered into their prospective lottery as Single Applicants.
What To Expect:
- The Southern Wake Academy Lottery will be held on Thursday, February 27, 2020.
- Lotterease will send results to the email submitted in the parent registration.
- Each applicant will receive an email from email@example.com with their personal lottery results, indicating whether the student has been selected or their numerical position on the waitlist.
If your student is SELECTED in the lottery, you will have a limited time to CONFIRM your student's attendance in Lotterease. You will then receive an "Attendance Confirmed" email with further instructions, including a link for your student's ENROLLMENT PACKET and the time frame in which it is to be submitted.
- PARENTS ARE RESPONSIBLE for checking email updates from Lotterease and responding within the given time frame.
Southern Wake Academy will host Open House evenings, from 6:45PM - 8:00PM, on the following dates:
Middle School
Wednesday, November 20, 2019
Tuesday, January 7, 2020
Tuesday, February 11, 2020
High School
Thursday, November 21, 2019
Thursday, January 9, 2020
Thursday, February 13, 2020
These evenings are provided for families who are considering Southern Wake Academy for their child. Each night will begin with an information session, followed by Student Ambassador lead tours to view classrooms and meet teachers. These evenings are open to both parents and students who are interested in learning more about Southern Wake Academy.
Applications for the 2020-2021 school year will open in Lotterease on December 1, 2019.
What is the Lotterease Seal of Transparency and Fairness? When you see the Seal on a school website, you can be confident that your application will be included in the school lottery in a fair and transparent way.
That is because Lotterease is an independent automated lottery system that the school uses to manage their lottery and waitlist. Since Lotterease is an independent system, the school staff do not have the ability to manipulate or adjust the lottery outcome. They must work within the requirements of the system. In addition, all activity that takes place with your application is tracked in a history log that you can view at any time by logging into the parent portal.
If the school you want your child to attend displays the Lotterease Seal of Transparency and Fairness, you can rest assured that you child will get their fair chance to attend the school.
Southern Wake Academy (SWA) admits students without regard to race, sex, disabilities, color, religion, or national or ethnic origin. All students who live in North Carolina are eligible to apply for admission. Families provide transportation for SWA students.


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Dude gets hit with a bike for fucking in park!!!
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text: Cashboard was developed by Moqod for entrepreneurs who want to have a good insight into their cash flow. With Cashboard, you can make a dynamic cash flow forecast, with a direct synchronization with accounting. It was aimed to replace time-consuming and error-prone Excel models that have to be adjusted manually every time. It contains smart graphical visuals with expected income and expenses ideal for creating cash scenarios. Cashboard is available on the iPad, so it is perfect for finance meetings and presentations.


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Title 16
317.4 Preemption.§ 317.4 Preemption.
The Federal Trade Commission does not intend, through the promulgation of this Rule, to preempt the laws of any state or local government, except to the extent that any such law conflicts with this Rule. A law is not in conflict with this Rule if it affords equal or greater protection from the prohibited practices set forth in § 317.3.


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IRVING – Construction is underway on a new 105,565-sf Element Hotel in Las Colinas.
The 157-room extended stay hotel will be built on Carpenter Fwy. and Meadow Creek Dr. near Spur 348.
The 12-story hotel will be owned and operated by Houston-based Lodgic Hospitality.
See also: Mayse & Associates to develop new Element Hotel in Irving, Texas (Hotel Management)
Our twice-weekly e-newsletter provides a quick overview of Texas real estate markets. Because your time is valuable.


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Dec 22, 2014
It's our massive Christmas episode for this year! In this episode we all pitch a Christmas-themed podcast idea - from favourite Christmas songs to bad presents to Australian television from the 90s.
Hosted by Ben Vernel, Murphy McLachlan, Roland Hoffmann, Timothy Clark and Peter Jones.
Please rate and review us on iTunes, like us on Facebook and follow us on Twitter @IsThisThePodcas


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News » Politics
Watch: (T)iffany (T)rump drops 'T' from Queer Acronym. Is it Time to Drop the 'T' from her Name?
President Trump's youngest daughter Tiffany Trump spoke at his Pride event in Florida this week and used the acronym LGBQIIA+ to describe the queer community, leaving the out the usual "T," which represents the trans community.
More Than 1,000 LGBTQ Candidates are Running for Office. Who Will Win?
Today the LGBTQ Victory Fund, a national organization specifically dedicated to electing LGBTQ leaders to public office, released its inaugural report detailing both the progress and work that lies ahead for greater LGBTQ political representation.
How Trump Plowed Through $1 Billion, Losing Cash Advantage
President Donald Trump's sprawling political operation has raised well over $1 billion since he took the White House in 2017 — and set a lot of it on fire.
South Australia Moves to Ban 'Gay Panic' Defense
South Australia has moved forward with a bill to revoke "gay panic" as a defense in court for perpetrators of anti-LGBTQ crimes.
Trump, Biden Go on Offense in States They're Trying to Flip
President Donald Trump and Democratic rival Joe Biden went on offense over the weekend as both campaigned in states they are trying to flip during the Nov. 3 election, just over two weeks away.
Opinion: Next Debate Needs an LGBTQ Question
The final presidential debate set for October 22 must include at least one question about LGBTQ issues, especially since President Donald Trump has spent his entire term rolling back our rights and attempting to make us invisible.
For the LGBTQ Community, Even Small Races Can Have Big Impact
Politics begin at the local level, where community organizers and volunteers are part of the foundation from which future state and national candidates sprout. San Diego provides a case study about the impact of LGBTQ politicians and voters.
Trump Leans into Fear Tactics in Bid to Win Midwest States
President Donald Trump leaned into fear tactics Saturday as he accused the left of trying to "destroy the American way of life" in a late reelection pitch to voters in Michigan and Wisconsin.
Majority of Voters Tilt Toward Biden as Health Issues Weigh Heavily
At least half of voters prefer former Vice President Joe Biden's approach to health care over President Donald Trump's, suggesting voter concern about lowering costs and managing the pandemic could sway the outcome of this election, a new poll shows.
Trump on Defense, Courting Voters in Two Must-Win States
Backed into a corner and facing financial strains, President Donald Trump went after his opponent's family and defended his own struggle to contain the pandemic as he fought to energize his sagging reelection bid in the nation's Sun Belt.
For Grateful NBC, Savannah Guthrie Changes the Subject
Savannah Guthrie did more than just display her journalistic chops at NBC News' town hall with President Donald Trump. She changed the subject for her bosses.
Watch: At Town Hall, Biden Vows to Protect LGBTQ Rights
Joe Biden vowed to protect the rights of LGBTQ Americans during his Oct. 15 Town Hall on ABC, assuring the mother of a transgender daughter he would reverse Trump's anti-LGBTQ actions.
Twitter Changes Hacked Content Rules After Biden Story Furor
Twitter said late Thursday it was changing its policy on hacked content after an outcry about its handling of an unverified political story that prompted cries of censorship from the right.
Harris Suspends Travel After Staffer Tests COVID-19 Positive
Joe Biden's presidential campaign said Thursday that vice presidential nominee Kamala Harris will suspend in-person events until Monday after two people associated with the campaign tested positive for coronavirus.
NM GOP Shames Out Candidate for Gay Adult Past, Dems Defend Him
New Mexico's Democratic Party, and many voters, are looking beyond recent revelations that an out candidate for the state House of Representatives had roles in gay adult films in the 1980s.
NBC Faces Backlash After Agreeing to Trump Town Hall
NBC News faced a sharp backlash to its decision to host President Donald Trump for a town hall Thursday in direct competition with ABC's event with Democrat Joe Biden, including a social media call to boycott the network.
After Independent Coronavirus Test, NBC Sets Trump Town Hall
NBC News agreed to put President Donald Trump before voters in a town hall event on Thursday after the president submitted to an independent coronavirus test with the results reviewed by Dr. Anthony Fauci.
Fighting in Swing States, Trump Also Forced to Play Defense
President Donald Trump is being forced to play Electoral College defense with a trip to Iowa, a state he won handily in 2016 but where Democrat Joe Biden is making a late push.
SCOTUS Declines to Review Court Ruling Ordering Medically Necessary Care for Transgender Prisoner
The U.S. Supreme Court has declined to review a federal court decision ordering the Idaho Department of Corrections (IDOC) to provide medically necessary gender confirmation surgery to Adree Edmo, a transgender woman.
President's Campaign Sends Out an Invite to a Trump Pride Rally... But Forgets the LGBTQ
Did you get your invite to the Trump Pride event tonight?


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Last Friday, on October 25, 2019, the U.S. Attorney General William Barr decided two cases that could have a significant impact on an individual's eligibility for certain types of immigration relief. Both cases pertain to an individual's criminal history and its impact on his or her ability to remain in the United States. In Matter of Castillo-Perez, the Attorney General held that an individual with two or more convictions for driving
Immigration and Firm News
Subscribe to this list via RSS Blog posts tagged in Removal Proceedings
On December 4, 2018, Mr. Carlos Rojo-Ramirez, of Colorado, through his attorneys David. L. Kolko and Jennifer Casey (Kolko & Associates, P.C.), challenged President Trump's unlawful designation of Matthew G. Whitaker as Acting Attorney General of the United States. In Rojo-Ramirez v. Trump, et. al., (18-cv-03125), filed in the U.S. District Court for the District of Colorado, Mr. Rojo-Ramirez asserted that U.S. Immigration Judges are temporarily operating without any legal authority
In his Executive Order, Border Security and Immigration Enforcement Improvements, (January 25, 2017) President Trump directs the DHS Secretary to use the "process of expedited removal" under Section 235(b) of the Immigration and Nationality Act (INA or Act) to individuals present in the United States who cannot affirmatively show that they have been continuously physically present in the United States for two (2) years prior to the date of their
Tagged in: Due Process Expedited Removal Immigration and Customs Enforcement President Trump Removal Proceedings
Around the office lately, I've noticed an increase in consultations related to DUI arrests. For many immigrants, a DUI arrest begins the one-way trip back to their home country. For any arrest, proper legal counsel should be sought from an immigration attorney to determine whether the arrest carries immigration consequences. For most permanent residents and people in lawful status, one simple alcohol-related DUI causes little harm to one's immigration status. However,
Tagged in: DACA Deportation Detention Issues DUI Removal Proceedings
On March 3, 2016, Partner Jennifer Casey appeared on Colorado Public Radio's "Colorado Matters" program to discuss the lengthy backlogs at the U.S. Immigration Courts in Colorado. Currently, the Immigration Courts in Colorado have the longest delays in the country, with the average case processing time of 933 days. Listen to Jennifer's insights on these issues here: http://www.cpr.org/news/story/denver-s-immigration-court-has-longest-hearing-delays-us
Tagged in: Denver Immigration Court Immigration Reform Removal Proceedings Unaccompanied Alien Children
The Department of Homeland Security (DHS) has recently stepped up its immigration enforcement efforts. Starting this week, Immigration and Customs Enforcement (ICE) has begun conducting "immigration raids" across the country targeting individuals and families who have entered the United States within the last two years and who have an order of removal from the U.S. Immigration Court. Many non-citizens in United States can be caught up in these caught up in
Tagged in: Border Crisis ICE Immigration Raids Refugees Removal Proceedings
Over the past two years, due to a major shift in priorities by the Department of Homeland Security, as well as a very understaffed court, the Denver Immigration Court put thousands of cases on hold and set hearings out to a "place holder" date of November 29, 2019. In recent weeks, the Colorado Chapter of the American Immigration Lawyers Association has been informed by the Court that it will begin resetting
US Immigration and Customs Enforcement (ICE) published new guidance in June on the care of transgender adults in immigration detention, in a Memorandum titled "Further Guidance Regarding the Care of Transgender Detainees." The Memorandum provides guidelines in several areas of detainee care, including intake procedures, determining housing placement, medical care, conducting searches, and access to clothing and commissary hygiene products. Notably, the guidance provides that transgender individuals may be assigned housing
Tagged in: Denver Immigration Court Deportation Immigration Court Migrant Children Removal Proceedings
Respondents in removal proceedings have been having their upcoming hearings rescheduled in recent months, to a date in 2019. This date happens to be the day following Thanksgiving in 2019. Over the past several months, many immigration courts around the country, including Denver, have been vacating or cancelling scheduled hearings and resetting those hearings to November 29, 2019. This date, however, is merely a "place holder" on the court's docket to
Tagged in: Deportation Immigration Court Removal Proceedings


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Type: Posts; User: dagosr
Hi I know it's an old post but I'm having this exact same problem, did you fix it and how?
BTW I've already tried in different cars and with two different batteries.
So what version is the one that uses the silver ones?
And they are just the regular aluminum, regular shafts but the same dimensions?
And is there very much difference between them? Is it worth...
Hi guys I would like to know whats the difference between the silver shocks and the dark ones and what Revo version have each.
Yeah I learned that the bad way, after that I don't even run the cars on the dry sand because it's a headache to clen and remove...that was the first and last time I ran my RCs on the beach.
I have a Slash 4x4 Platinum when i bought it I bought 2 Venom 3S 5000 mah lipo batteries...last year I was running it on the beach and a wave caught the car so it was submerged and the ESC burned,...


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Back To Menu
Cold Sandwiches and Wraps
Club Sandwich
Ham, turkey, bacon, tomatoes and lettuce
(Select 1) Side:Steak Fries Seasonal Fresh Fruit Potato Salad Onion Rings +$1.59
(Optional) $$ Add:Cup of Soup +$2.89House Salad +$2.89
Have you tried this item? Pop it!
Help other diners know what to expect by sharing your experience.
4 people have popped this item


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Østerøvej 2
5800 Nyborg
Phone:+45 65 31 31 31
The Bistro is a cozy grill restaurant located in the middle of the hotel with direct access to an outdoor terrace and the hotel park. The price level is generally lower than in the Panorama Restaurant and serve great quality food for the entire family.
Østerøvej 2
5800 Nyborg
11:00 - 23:45


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The Black Collar Crime Series relies on public news stories and publicly available information for its content. If any incorrect information is found, please contact Bruce Gerencser. Nothing in this post should be construed as an accusation of guilt. Those accused of crimes are innocent until proven guilty.
Christopher Keys, a student pastor at Wesleyan Drive Baptist Church in Macon, Georgia and a former teacher at Tattnall Square Academy, stands accused of faking his kidnapping to cover-up hiring a male prostitute.
A Georgia Christian school teacher has been charged for solicitation of sodomy after local authorities looked into a robbery and kidnapping that was spawned from a rumor 'circulating around Facebook.'
The Bibb County Sheriff's Office arrested 56-year-old Christopher Keys and are investigating the robbery that he initially reported on May 19.
They shared in a Thursday press release that the office had received an inquiry about a rumored 'carjacking and kidnapping' that took place on Wednesday at the CVS Pharmacy on 1600 block of Forest Hill Drive.
According to an incident report, deputies met with Keys at the Regency Inn & Suites for calls about an armed robbery.
Keys claimed that he had been in the motel when he heard a knock at his door. Once he opened the door, two masked men robbed him of his wallet, house, truck and work keys, and a cell phone. One of the men was armed, Keys told deputies.
He told authorities that he was able to get his cell phone back only after a stranger retrieved it from a nearby Walmart parking lot.
Keys explained to deputies that he was supposed to meet a man in his hotel room, having responded to an ad on Craigslist.
An investigation revealed that Keys had been frequently visiting the hotel since January.
Key subsequently told an acquaintance that he had been kidnapped in his truck at a nearby CVS, forced to drive to the motel, and robbed. After a woman posted Keys' story about the kidnapping and robbery on Facebook (above), it was shared hundreds of times, prompting WMAZ-TV to look into the rumor.
As it turns out, Keys met with police at the hotel after the robbery, telling a sheriff's deputy that "he liked to play around and was married to a woman," the station reports. In an interview with the deputy, Keys even revealed his plan to tell his family that he was kidnapped at the CVS. Two days later, he was arrested and charged with solicitation of sodomy, a misdemeanor. (Although the U.S. Supreme Court struck down sodomy laws in 2003, Georgia's solicitation of sodomy statute has been upheld.)
Keys recently worked as a teacher at Tattnall Square Academy, where he taught upper-school Bible, worked with the chapel band, and served as coordinator for the Fellowship of Christian Athletes, according to his now-deleted bio (above).
"I am a people person and love to teach young people the truths of the Bible," he wrote in the bio.
"I have been married for 20 years to my wife Jennie. I am a graduate of FPD and Mercer University and Southwestern Seminary. I am currently the student pastor at Wesleyan Drive Baptist Church in Macon and I've been in student ministry for 28 years."
Keys also once worked as a bailiff for the Bibb County Sheriff's Office, which arrested him. Sheriff's investigators are still searching for the robbery suspects, who made off with Keys' wallet, cell phone, and keys — although his phone reportedly was recovered in the parking lot of a nearby Walmart.
Bruce Gerencser, 63, lives in rural Northwest Ohio with his wife of 42 years. He and his wife have six grown children and thirteen awesome grandchildren. Bruce pastored Evangelical churches for twenty-five years in Ohio, Texas, and Michigan. Bruce left the ministry in 2005, and in 2008 he left Christianity. Bruce is now a humanist and an atheist. For more information about Bruce, please read the About page.
Are you on Social Media?
Follow Bruce on Facebook and Twitter.
Thank you for reading this post. Please share your thoughts in the comment section. If you are a first-time commenter, please read the commenting policy before wowing readers with your words. All first-time comments are moderated. If you would like to contact Bruce directly, please use the contact form to do so. Donations are always appreciated. Donations on a monthly basis can be made through Patreon. One-time donations can be made through PayPal.


text: So I shall. I don't have a firm date yet, just a hand wave "3-5 months". I know people have put together TX specific tips & procedures lists in the past? Where's a good place to find the latest edition? I believe I'm going to be partially financing but not through Tesla. Already reaching out to a bank I've worked with before. This was kinda sudden but is also a hurry-up-and-wait situation so I'm not sure how successful I'll be about locking in a rate. Thanks in advance for any help.


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Speak Up! Your Customers are Listening
What is the personality of your tea shop or tea room? And what type of tea culture does it reflect and aim to serve?
Answering these questions is important in communicating effectively with your customers. When customers see your promotions, they should experience an immediate "Aha!" moment that identifies this item as coming from your shop and no other, and of course, makes them want to read what you have written. To achieve this, ask yourself if your logo, your company colors, your choice of type font, and your writing style matches the personality of your business. Get help from graphic designers to brighten up the look you already have or move it into the direction you want. Then, use the asset of consistency by stamping that personality on any or all of the following communication tools to make them work even more effectively for you.
Store Promotions
Anyone who visits your shop is already "in the market" so make it easy for them to buy.
Price everything on display. Make it easy for customers to make a decision, and speeds up the order-taking for your employees.
Rate your products. Just as bookshops note "good reads" by their staff and customers, or what's on the best-sellers' lists, so should you boast about your best or newest products. "These are the best lemon cookies I ever had!" or "Smooth, silky brew that takes milk well" are ways to describe foods and teas you offer. Get personal here and write one-sentence descriptions in just the way you would talk to customers. Change these often, and also include "Ask me about this!" cards if you believe the product needs more one-on-one information.
Always keep a guest book open by the register with pen attached! Ask everyone, whether they buy anything or not, if they would like to be on your list to know about sales or particular products. Use this to update snail and email lists, use as a tab list to telephone customers when their favorite product comes in, and to send out other promotional materials.
Identify yourself! Every bag of tea, every shopping bag, every gift box should have a label that identifies your shop name, address, telephone number and email address and/or web site address. Nothing frustrates a customer more than to reach the end of a great bag of tea and not know where or how to reorder. Don't rely on their memory, label everything! No labels? Pass out a business card or drop it into the shopping bag. It's the least expensive, most valuable advertising for repeat sales.
One-page newsletters, fliers, and postcards are relatively easy to produce, and are very effective ways to literally reach the customer at home. To stand out from all the other mail, however, you need to use your logo prominently, use color stock or colored ink as the budget allows, and write something meaningful. Ask yourself why the customer should make an unscheduled trip to your shop? Something is on sale? Something is in short supply or available only in one season? Something is new, unusual, rare? Be specific, set time limits for the offer, and always include your basic information even if customers come in daily: address, phone, hours, and web address, as applicable. Note: The postcard, in particular, is a snappy, inexpensive-to-mail item that is perfect for focusing on one item, idea, or service. Get some blank ones, too, with your logo on the back, and use them for one-on-one notices to your best customers. When was the last time you got a handwritten postcard? Wasn't it great?
Your customers will be astonished that you will take the time to personally call them about the new shipment of their favorite shortbread cookies has arrived or that the hunt for that unusual strainer is over. Ask them if there is anything else they need�you might be surprised to learn what your inventory is missing, and something about talking one-on-one on the phone can generate a lot of good ideas. Even leaving a message on their voicemail about new products or that their order is in will be effective and personal. This technique is best for the most specific or unusual products. For more generic promotions, use print or email tools.
For the Computer Savvy
Using the computer is a neat, clean, quick way to educate your customers and, as important, keep your inventory and customer lists up-to-date. Here are some promotional ideas to consider:
Create Email Newsletters. These are terrific tools for informing existing customers of new teas in stock, unusual gift items or additions to your accessories inventory on a regular basis. They can be used to discuss a particular tea, health benefits, or how-tos that you want to share. You can be brief (1,000 words or less;) you can be chatty and breezy and totally informal; and, by doing this letter on a regular schedule (monthly, bi-weekly, even quarterly) you will create and sustain customer support.
Answer Questions. After a while, you should be able to determine what the most common questions your customers ask. Keep a list in the shop and develop a list of those questions and your answers for your employees and your customers to read. Have a file on your computer so that you can easily copy and paste when customers email you with similar questions. Your staff and your customers will appreciate it.
Develop a Website. This can be a simple one-page site that lists operating hours, address, and directions to your shop, or it can be a full-scale effort with information, current inventory, and online shopping convenience for customers who can order teas anytime, and your staff can fulfill these orders when you are less busy.
How to Get Started. Not familiar with computer programs? Believe you don't have the time to run a shop, learn new programs or supervise computer communications? You can still make computers work for you by either hiring someone to do the work or trading the work for goods and services (LOTS of computer people LOVE tea!) Learning to delegate is the key to growing any business. Ask staff and friends for references, post help-wanted notes on bulletin boards at local community colleges, or ask your customers for leads. Among all the recommendations, you'll find someone who can meet your needs and your budget.


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GOAL: Create Safer Bike Infrastructure on Colchester Ave
GOAL: Improve Biking Infrastructure Along Colchester Ave
Colchester Ave serves as a critical connection for bike commuters traveling between Burlington and other destinations in the region. Given the frequency of use by cyclists, this corridor is identified in both Plan BTV Walk Bike and the Chittenden County Regional Active Transportation Plan as a route to prioritize for improvements. Specifically, a safer connection is needed both for those climbing and descending the hill between the Winooski Bridge and UVM.
Local Motion, in collaboration with the Burlington Walk Bike Council and other local residents, is advocating for better bike infrastructure between the bridge and East Ave.
Add your name in support of this campaign
THE OPPORTUNITY: Ask the City of Burlington and Public Works Commission to repurpose the existing public right of way with better biking infrastructure in order to create a safer Colchester Ave for everyone. Utilizing the public right of way along both sides of Colchester Ave (both on the lower part of the hill by the bridge, and along the upper portion by UVM) would create space for safer bike facilities. A show of public support will help make these changes possible.
CURRENT STATUS: Although the City of Burlington has recently added a climbing bike lane to the bottom portion of Colchester Ave, there is insufficient room for cyclists to travel comfortably and safely along this stretch, particularly during winter months. What's more, the bike lane disappears when it reaches the top of the hill, and there is no downhill bike facility. Improvements are needed to make this critical connection more accessible, and on-street parking removal will be a key factor in making these changes possible.
THE NEXT STEP: Add your name via the above link to show your support. Please also consider contacting DPW at email@example.com or 802-863-9094 x3, and/or coming to speak on this issue at the Public Works Commission Meeting on Wednesday, May 15th, 2019 at 6:30 PM. Please fine sample letters and email addresses here.
GOAL: A Safer North Avenue in Burlington
Local Motion, in collaboration with city, neighborhood and other local leaders, helped to shape the vision for a safer North Avenue for everyone: people walking, biking and driving. North Ave serves as a critical connection between downtown Burlington with many of Burlington's most important destinations. So, what happens to North Avenue affects the daily transportation needs of residents across the city.
THE OPPORTUNITY: A pilot project was designed to convert the 4 vehicle lane section of the Avenue between Institute Rd and Shore Rd/Heineberg Rd to 2 lanes with a center turn lane and bike lanes in both directions. This design was chosen because it would improve safety on North Ave for everyone: people walking, biking and driving. A 4-lane North Avenue would never be built today because it is an unsafe, outdated design. The center turn lane allows a continuous flow of traffic, while reducing potential rear end and sideswipe conflicts, while making more room for bike lanes. It's a winning design that will increase the safety of North Ave for all users, regardless of choice of transportation.
CURRENT STATUS: After a year of temporary implementation, the pilot was voted into permanence on Monday, July 10th, 2017!
The goal of this pilot was to show that North Avenue can be safer and align with contemporary needs.
All Burlingtonians deserve a better street and a better neighborhood that ensures that the kids, adults, and grandparents in the New North End (and Old North End) are safer, healthier, and wealthier.
Learn More
Protected bike lanes are part of a transportation revolution in cities and towns across the US!
Read more about the Myths and Facts of this common type of redesign project known also as a "Road Diet."
Take a look at the City of Burlington's website for the latest project updates.
Check out an Avenue for Everyone for more background on the pilot.
BURLINGTON Better by Bike
BURLINGTON Better by Bike is a campaign to make Burlington the best small city for biking on the East Coast. First came "Go for Gold." That paved the way for "PlanBTV Walk Bike." Want to know more? Read on!
Here's the backstory. In 2012, Local Motion began a concerted effort to accelerate the pace of change for better biking (and walking) in Burlington. We set our sights on achieving gold-level recognition as both a "Walk Friendly Community" and a "Bicycle Friendly Community" (both of which are national recognition programs). To that end, we worked with a variety of partners to create a "Go for Gold Blueprint" that assessed Burlington's strengths and weaknesses and identified opportunities for improvement for both walking and biking. You can read more about the Blueprint at this link, as well as download both a two-page summary and the full text of the Blueprint itself.
The Go for Gold Blueprint led to the creation of a "Go for Gold Leadership Team" under the aegis of the Burlington mayor's office. The purpose of this team—which included high-level representatives of a variety of city departments as well as non-municipal partners—was to identify and pursue strategies that would advance the goals identified in the Blueprint. The Go for Gold Strategic Plan was released in early 2015, and is available at this link.
In mid-2015, Burlington Public Works launched the city's first-ever comprehensive planning effort for walking and biking, called "PlanBTV Walk Bike." Local Motion was appointed to serve on the core technical committee for that effort, and has played a key role on two fronts: ensuring that the plan is both visionary and practical, and building support for its approval and implementation. Read more about PlanBTV Walk Bike and learn about how you can help implement the plan at this link.


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Digital Innovation in Healthcare: Creating a Health Service Fit for the Future
- 11-10-2018
- 08:30 - 16:30
- The Bridgewater Hall, Manchester
Dr Ishani Patel is a GP, cancer advisor for RMPartners accountable cancer network and co-founder of Lantum with a wide-ranging portfolio evolving her to be a leading voice in GP recruitment, retention and engagement at scale. At Lantum she has championed innovation and sustainability for the GP workforce. Lantum is an evolving platform that uses artificial intelligence and machine learning to enable organisations to deliver primary care at scale. It is utilised in 40+ Federations across the country, has saved the NHS over £7m and enabled over 4m primary care NHS appointments. The platform has also offered a stability for areas that are struggling to recruit by offering engagement, talent retention and resilience to the system. Ishani has also held leadership roles at Transforming cancer services team (London) at NHS England, RCGP and Macmillan to drive forward quality improvement in early diagnosis of cancer and a member of the Harvard Medical Innovators and leadership alumni.


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The outbreak of COVID-19 has created a time of both personal and economic uncertainty. On March 9, 2020, Retail Consult implemented a work-from-home, remote workforce model to protect our employees, clients and partners. Most of our clients and partners are also working from home. Working collaboratively we have been able to safely and productively continue our business activities and we will bring continuity and innovation to navigate this time of crisis together!
Check here how Retail Consult delivers Oracle Retail Solution for Farmatodo with a 100% Remote Project Model


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While this website provides general information, it does not constitute legal advice. The best way to get guidance on your specific legal issue is to contact a lawyer. To schedule a meeting with an attorney, please call the firm or complete the intake form below.
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Sargon of Akkad- initiated program od conquest--- conquered cities of Sumer, established direct control over Mesopotamia--- and transformed Sumer and Akkad into first known empire.
Middle Kingdom- reestablishment of central government—pharaohs represented good shepherds—secured border with Nubia
Hatshepsut- woman pharaoh—launched military campaigns and extended trade and diplomacy—most ambitious builders of Egyptian history—new kingdom pharaoh
Khufu Ship- sealed into pit of Giza pyramid—built by Khufu (old kingdom pharaoh)
Royal Road-
Hoplite- Greek soliders—heavy armor—main tactic was the phalanx formation
Marathon- Athenian victory over Persians—they had no help from Sparta
Plato- strove to vindicate Socrates—worked in his academy—wrote series of dialogues such as symposium (the republic, elements of benign tyranny) ???
Cosmopolis- Long distance migration and trade (spread east to central asia)—cities (imporatation of greek officials and soliders---Alexandria)—wealth and poverty (economic growth)????
Punic Wars-
Cuneiform- an early writing system that bean to develop in Mesopotamia in the 4th millennium B.C., by 3100 B.C. its distinctive markings were impressed on clay tablets using a wedge shaped stylus
Babylonian Empire- Hammurabi was ruler of Babylon--- used politics and writing as weapons—durable state
New Kingdom- invaded by Hyksos-- dissolved power of Pharaoh—imperial expansion—rise of aristocracy—Egypt reached height of power
Amenhotep IV- changed hieroglyphics--- noted for abandoning traditional Egyptian polytheism and introducing worship centered on the Aten (monotheism)—undermined influence of Amon's priests
Osiris- first pharaoh of Egypt and first god to hold kingship--- betrayed by brother Seth and killed—sister and wife picked up remains and reassembled pieces for mummification
Zoroastrianism- universal faith—taught by Zoroaster—religion common to all—supreme God—lead good life by performing acts of compassions and charity
Athens- capital of Greece--agriculture economy—government (Areopagus city council)—"Democratic"
Delian League-
Aristotle- student of Plato—established rules for syllogism—good conduct is rational conduct—preferred government of checks and balances rather than pure democracy—information about reality is gained by sensory experience
Roman Kingdom-
Lugal- "big man", war leader, early dynastic period
Code of Hammurabi- legislation, business deals, public resources laws—282 laws—regulated commerce, resources, social interactions, and criminal laws
Pharaoh- ruler over Egypt—personification of Egypt
Imhotep- right –hand man to Djoser—learned medicine, theology,


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WB0277 JB Soft Cracked Natural is a water base PVC free base for adding WB-99 PS colors into to create colored cracked designs for 100% Cotton.
Mix colors using the WB formulations provided in the RGCC Color Software. Mixed colors may be printed from 86 to 156 mc in (34 to 62 mc cm) mesh range. The tack free formulation allows increased coverage; therefore, finer mesh counts may be used for softer hand with minimum loss of opacity. Mix colors according to the desired color formula for best results.Disclaimer: Not all Rutland products are available in every country. Please check with your local representative for availability. The data presented in this leaflet are in accordance with the present state of our knowledge, but do not absolve the user from carefully checking all supplies immediately on receipt. We reserve the right to alter product constants within the scope of technical progress or new developments. The recommendations made in this leaflet should be checked by preliminary trials because of conditions during processing over which we have no control. Recommendations for use do not constitute a warranty, either express or implied, of the fitness or suitability of the products for a particular purpose.


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We can't get enough of our tall cozy boot socks this season. Made to be versatile with your fall wardrobe, the Kay uses multi feed knitting for a unique design and delicate feel. For added durability, each pair sports reinforced toes and heels, while warm cotton hugs you just in the right places.
- Seamless Toe Closure
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Women's Sizes 5-10
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MPP joined local Liberal candidate to speak to voters about Liberals' positive plan
FERGUS—Michael Coteau, the third-term MPP and Ontario Liberal leadership candidate, campaigned Friday with Dr Lesley Barron, federal Liberal candidate for Wellington--Halton Hills.
FERGUS—Michael Coteau, the third-term MPP and Ontario Liberal leadership candidate, campaigned Friday with Dr Lesley Barron, federal Liberal candidate for Wellington--Halton Hills.
"This is a critical election here in Fergus and across Ontario," said Coteau. "We know that Conservatives may claim to be 'for the people' but their cuts hurt children and families. We need to elect strong, local Liberal candidates to ensure we choose forward in this campaign. I'm so pleased to join such a strong, local, experienced candidate who I know will do a fantastic job representing these communities on Parliament Hill."
Dr Lesley Barron is a surgeon at the Georgetown Hospital. She was raised in Ancaster, studied medicine at Western University and practiced in London, UK and Australia, where she conducted research into breast cancer and transplant surgery.
Michael Coteau immigrated to Canada as a child and grew up in Flemingdon Park, a working-class neighbourhood in North York. The first member of his family to graduate high school and university, he started his own small business, worked as a community organizer and head of a national nonprofit. He was elected to the Toronto District School Board three times and served as vice-chair of the board, championing digital tools in the classroom, equity strategies and community use of schools. Coteau was elected three times as Member of Provincial Parliament for Don Valley East, and served in multiple ministries where he was tasked with bringing people together to fix tough files, including supports for children with autism, reforming services for children in care, delivering a successful Pan-Am Games, supporting film and cultural economic development, and implementing an anti-racism strategy. He and his wife, Lori, are raising two young daughters.
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When you want to do something that betters your life, there is nothing more productive than a hobby. When you learn about the hobbies out there, you can select one you like. The article below provides you with all of the information you need to know, so check it out.
Making music can be a fun hobby. The next step is trying to decide what instrument appeals to you. Decide whether or not to train with a professional or use books and instructional videos. Start slowly and build on it when you have the time, and your skill will grow.
A good hobby that is not as expensive as it once was is photography. It's likely that you can get started immediately if you already own a digital camera. Remember that you do not need to be incredibly artistic for taking great photos. Reading a couple books can help you become a great photographer.
If you don't know how to start making money with your hobby, begin by choosing a niche. What special skills do you possess? Look for things that you enjoy but that others do not want to do. This will help you find a money maker.
Be careful to set a realistic price for items you sell when you are trying to make some money from your hobby. You need to be able to support yourself. Figure out what the costs involved are and charge more to make a profit.
Gaming online is a growing hobby that many are passionate about. This can help you escape reality. Gaming is a great way to fill up any free time in your day.
Boost your handwriting skills by learning calligraphy. You'll find that the start-up costs are minimal, and learning how to make those beautiful calligraphy curves is rewarding and calming. You can take a class or learn on your own. Whatever the case may be, you'll have a big appreciation for writing after you're done.
If work stress has you down, hobbies can make all the difference. A hobby can be totally unrelated to what you do for work.
Never allow guilt to overwhelm you when you are having fun. Hobbies help you to be a well-rounded individual, creating a balance between responsibilities and enjoyment. Each plays a big role in life, so make sure you work on hobbies only when feasible.
Keep your area space organized. That way, you will always know where to find supplies. Additionally, your work area should stay organized to keep you safe. You don't want to hurt yourself because something is in the wrong spot.
If you have a hobby that you're going to use scissors for, be sure they're cleaned off first. Wipe your scissor blades down after you use them so that you can prevent lint from building up on them. Soap and warm water can be used for a thorough clean, but be sure to dry them completely before putting them away. If your messes are extra sticky, you can use nail polish remover to remove the adhesive.
Find a friend who likes the same things you like, and ask them to meet up to do it. Even if you only do it once or twice every month, that will make you do your hobby. It will also make friendships stronger.
Would you like to make a hobby of being fit? That can blend a lot of different hobbies, actually. You can bike, join a gym or even kayak as your fitness hobby. You might find yourself dipping in the pool a lot more. Fitness is an integral part of overall health.
If you are searching for a hobby and maybe you are a tad overweight, think about pairing the two together! Get into the pool and swim, or set your sights on training for a marathon. No matter what you choose in the fitness area, you body and mind will surely benefit.
Think about following a particular sports team, whether in hockey, baseball, basketball, football, or soccer. To really become a fan of the game, it is best that you acquire as much knowledge about the sport as possible. You also want to actually have fun when you watch the sport. This can really help you to pass some time during the season the sport is being played in, and you may make friends with those that enjoy the same team as you.
Practice Safety
Surfing is a fun water-based hobby. Used surfboards can be purchased at a huge discount, and lessons are also not too expensive. The added benefit is the exercise that you will experience is great for building the strength of your leg muscles.
Practice safety measures while cooking. If you wear loose clothing, you may end up with a fire on your hands. Tie back your hair, wear tighter sleeves and put on your apron. Practice safety first whenever you're in the kitchen.
Research any organizations or groups that are based on the hobby you love. If so, you can meet lots of people who share your interest and be in on the latest news flashes and information. Organizations help you keep up with what is trending concerning your hobby.
You do not need to restrict yourself to just one hobby. Diversifying your pastimes is as important as diversifying your portfolio. Choose wisely, and you will always have a hobby to enjoy.
Most hobbies start with natural talent. Artistic types may engage in painting various items. You could make gifts for friends and relatives or make some money.
Jigsaw Puzzles
Gaming online is a popular hobby that a lot people choose to be involved with. If you spend too much time on them, you can start to lose track of reality. Gaming is a great way to inexpensively fill your time.
Many people enjoy working jigsaw puzzles as a hobby. Jigsaw puzzles come in a variety of types and present varying challenges. You can even laminate your finished product and hang them as unique artwork in your home. Make it a bit harder every time one is done.
Never choose a hobby that costs a lot just to begin. You want to make sure you will really enjoy this hobby before you invest too much. A lot of times, you can't recoup those losses.
You should not feel guilt when it comes to engaging in favorite hobbies, provided you do not neglect other duties. Hobbies can help teach you to balance pleasure and responsibility. Due to the fact that having this balance is important to having a happy life, you should get to work making it so for you.
Think about making a hobby your career. If it's something you're great at, like a sport, you can become a coach. If you're making something, you can profit from it.
Take the time to continue expanding your hobby knowledge in the future. Now, do you know which hobby to try out? Inaction is the only thing that is holding you back, so start enjoying your new pastime!
It is important that your hobby area be organized. Doing this will allow you to know where everything is, allowing you to reduce stress. Not only that, but the area will be safer. You don't want to get hurt because you were unorganized.


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Diane Prekup, Duster, Serenade Celebration, S
Most of our products are one of a kind. If an item is out of stock or not to your size/color preferences, please contact us regarding potential special order options.
It is possible that a retail sale in our Santa Fe store could coincide with your web purchase. In this case, we may sell out of the item(s) you selected. If that happens, we will contact you via email and adjust the total on your order or offer special order options.
Serenade duster in a medley of black fabrics, with graphic elements in paprika, plum, and azul. Mixed fibers, dry clean only.
38" Bust
38" Length Back
70" Width, Hemline
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100-Year-Old Church Demolished
[By Leigh Williams, Contributing Writer]
A Mt. Vernon church that has provided its congregation a place to gather and worship for nearly 100 years will soon be demolished. According to the Associated Press, the Saint Mary Catholic Church on North 14th Street will be torn down after maintenance costs on the building continued to grow and efforts toward preservation stalled.
A special Mass was held to say goodbye to the church after which the doors were sealed.
The church, which dates back to 1921, closed last year after a newer building was built next to the original chapel.
"Statues and artifacts from the old church have been moved to the new one. The lot will become parking and an expansion of the St. Mary's school playground. Bricks and beams from the old church will see new life in a wedding chapel in the southern Illinois community of Eldorado," the Associated Press states. The church was included in a 2008 walking tour of Mt. Vernon Landmarks which included information on the building stating the establishment of the church preceded the historic structure.
"In the 1860's there were a small number of Catholic families in Mt. Vernon. The prominent Judge Thomas S. Casey resided at 1314 Main Street, the house that has since become Hughey Funeral Home," the information states. Masses were held in the Casey home through 1880 when a small church was built at the North 14th Street location.
"In 1921, the little frame church was picked up and moved north to make way for a bigger, sturdier building. The small church, in its new location, was still used for Sunday Mass until May 30, 1922, when the new $30,000 brick structure, with a seating capacity of 230, was dedicated as the Immaculate Conception of Mary Church. Since that time, the church has been known as St. Mary Church or occasionally as Immaculate Conception Parish," according to the information provided.
The original wood frame church was used as the parish hall until 1929 when it was dismantled and the lumber sold for $140. The new, larger and more modern building has a seating capacity of 600.


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Taye Diggs Talks All American, Dating, & How Stella Got Her Groove Back Remake – Inside The Black Actor Studio
Taye Diggs joins Danny Royce in the studio as a guest on today's episode of Inside The Black Actors Studio. They discuss his illustrious career, How Stella Got Her Groove Back, dating, All American, craziest celebrity moments, upcoming projects, and so much more!
Join us on Inside The Black Actor's Studio to discuss the craft, artistry, and pathways of some of the most prestigious members of the black community. Host Danny Royce sits down with each guest as he dives down the rabbit hole of their journey and their passions. Only on Black Hollywood Live.


text: In recognition of Rare Disease Day 2014, the FDA haslaunched a new website resource which houses recorded educational topics about FDA and rare disease issues. Additional cross-cutting rare disease topics will continue to be added to this webpage over time. Some topics included are: Essentials of Interacting with the FDA; Introduction to Patient Focused Drug Development; Regulatory Applications for Products Intended to Treat Rare Diseases. See more here. (Source: FDA.gov, March 2014)


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|El Pino
Designed & hosted
Views featured on "Hot Property" & "Place in the sun" programmes
El Pino is ideal for those who want to mix peace and tranquillity with accessibility to sight seeing and activities. There is a great deal of space to explore outside around the house and as well as the privacy of your own pool and terraces and the delight and convenience of your own enclosed Andalucian patio.
The accommodation comprises four double/twin bedrooms, four bathrooms (two being en-suite) and three living rooms. In each of the twin rooms the beds can be put together and made up as a double bed if required.
The courtyard with vines and parasols is the summer living room for the house. Being completely enclosed it is quite secure for children and with its BBQ and expandable table is an ideal place to congregate.
The larger than average solar heated pool has shelter from the midday sun and is completely enclosed by walls on two sides and railings on the other two sides with a lockable gate.
From here you can lie on the sunbeds provided and look across the valley to the olive groves on the other side.
There is also a fridge for cold drinks in the casita by the pool.
For the more active there is a table tennis table which can be set up by the pool and a fishing net for retrieving balls.


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Fair Cop Unleashed
Join BBC Radio 4's cop-turned-comedian Alfie Moore for his latest stand-up tour show.
Fair Cop Unleashed is based on a dramatic real-life incident from Alfie's police casebook. Relive with him the thrilling ups and downs of the night a mysterious clown came to town and more than one life ended up in the balance. It was no laughing matter – but this show certainly is!
Enjoy Alfie's unique brand of humour hilariously woven together with his personal insights into his life on the front-line of the police force.
It'd be a crime to miss it!
"offbeat, revealing and very funny" Daily Mail
"lots of well-crafted jokes and a large dash of police gallows humour" Telegraph
"Brilliantly funny…. genuinely hilarious" David Mitchell
Alfie Moore
Alfie is an original and distinctive comedian with his niche area as a serving police sergeant. He came slightly later to comedy and brings a wealth of insights and comedy moments from his eighteen years on the beat, where a keen sense of humour has been the key to his success and survival! Born and raised on a council estate in Sheffield he was an apprentice in the steelworks before joining the Police. Early on in Alfie's career he finished runner up in a national stand-up competition and was well and truly hooked. He subsequently served a whole new apprenticeship, honing his craft at comedy clubs all over the country. Alfie has an observational comedic style, which lends itself to witty, and sometimes gritty, anecdotes based on everyday modern policing. 'He's a very funny man' (Rhod Gilbert) 'Genuinely brilliantly funny' (David Mitchell) 'Very funny... a large dash of gallows police humour' (The Daily Telegraph) 'He walks the comedy beat with confidence' (Metro) 'Gloriously, life-enhancingly funny' (The Scotsman) 'His is a higher form of wit. delivered with lashings of good spirits and an effective slither of self-deprecation' (Chortle) 'Lots of well-crafted jokes and a large dash of gallows police humour' (The Sunday Telegraph).
See 4 tour dates featuring Alfie Moore
- 48-52 Canal Street
- Nottingham
- Website:
- castlerockbrewery.co.uk/pubs/the-canalhouse
- Enquiries:
- 0115 955 5060
Alfie Moore image © Idil Sukan/Draw HQ


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Recession talk may have dominated headlines over the past few months, but new data shows global sharemarkets paid out record dividends in the second quarter of 2019.
The total payout for the three-month period reached $US513.8 billion ($757.8 billion) – up 1.1 per cent on the previous year and a record for the quarter – according to data from global asset management firm Janus Henderson Investors.
The healthy dividends puts sharemarkets on track, resulting in an astounding $US1.43 trillion ($2.11 trillion) in cumulative income for the year – up 4.2 per cent.
"For investors who have chosen equities for income growth, the continued growth in dividends globally is clearly to be welcomed," Janus Henderson director of global equity income and portfolio manager Andrew Jones told The New Daily.
"With interest rates remaining at incredibly low levels in a historical context, the dividend yield of equities is very attractive relative to cash and bonds. Having an asset class that can have this yield and deliver income growth is attractive in the current environment."
While the pace of growth has slowed, Mr Jones said it was "not a cause for concern" given the growth experienced in previous years has been "exceptional", and the more recent slowdown simply reflects the moderation in sharemarket growth.
Australian performance 'quiet'
While Japan, Canada, France and Indonesia all enjoyed national records for dividend payouts, Australia's quarter was "seasonally quiet", marking a continuation of a five-year trend of stagnant dividend growth, the report found.
"Australia remains an attractive market for equity income, but income generation is dominated by a handful of very large, high dividend-paying companies," Mr Jones said.
"The top-10 Australian dividend payers account for 63 per cent of market income, with the financial sectors alone generating half of all market income."
Those financial services businesses are now facing a difficult run as record low interest rates squeeze their profit margins and, in turn, stifle any dividend growth.
"It therefore makes sense for super funds to consider diversifying internationally for income," Mr Jones said.
"Global GDP has still shown reasonable growth this year which has been a favourable, if slightly more muted, backdrop for earnings and dividend growth.
"Additionally, financials in a number of countries have shown good dividend growth having significantly strengthened their capital position."
Shane Oliver, chief economist with AMP Capital, similarly noted that Australia's share market performance has so far been lacklustre.
"Only 37 per cent of results have surprised on the upside [performed better than expected] which is below the long-term norm of 44 per cent, and 43 per cent surprised on the downside," he said.
Similarly, while 63 per cent of companies have reported an increase in their earnings, that figure was at 77 per cent this same time in 2018.
"Some retailers surprised on the upside and were confident about rate cuts and tax cuts boosting spending, but overall results so far point to constrained growth outside resources and a cautious outlook," Dr Oliver said.
Dr Oliver noted that more companies are yet to report, including 115 in the next week.
The New Daily is owned by Industry Super Holdings


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However before they can get their product and platform in place they need the advice of an experienced Financial Modeller. You will be working closely with the founders, building models that explore bond equity, debt, plus fractional lending.
This is initially a 3 month engagement, as always there is a strong chance of extension.
Key Skills:
- Financial modelling experience
- Experience of capital markets, equity funding or lending.
- You will ideally be available for immediate start.


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Pakistani religious groups angered by new law to protect women
A law enacted by Pakistan's largest province of Punjab to protect women from stalking, cyber crimes, sexual violence and emotional abuse has angered right wing groups, which have threatened nationwide protests if it isn't withdrawn.world Updated: Mar 17, 2016, 21:10 IST
A law enacted by Pakistan's largest province of Punjab to protect women from stalking, cyber crimes, sexual violence and emotional abuse has angered right wing groups, which have threatened nationwide protests if it isn't withdrawn.
This week, religious parties warned the PML-N government to repeal the Punjab Protection Of Women Against Violence Act by the end of the month.
The law, passed by the Punjab assembly in February, makes physical violence, abusive language, stalking, sexual violence, and psychological and emotional abuse of women cognizable offences.
Many quarters welcomed the law. "This is the best legislation I have seen passed in several years," said women's rights activist Fouzia Saeed.
The act includes remedies for victims of violence, criminalises all forms of violence against women and provides them with special centres that remove bureaucratic hurdles which complicate access to justice.
A toll-free number to receive complaints, district protection committees to investigate complaints and centres for reconciliation and resolution of disputes are also part of the law.
But the religious lobby is furious. A declaration issued after a conference held by religious parties said statements by government officials on the law and the execution of Mumtaz Qadri, the assassin of former Punjab Governor Salmaan Taseer, were against the Shariah, the ideology of Pakistan and the Constitution.
Representatives of more than 35 religious parties huddled at Mansoora in Lahore for the All-Pakistan Ulema Conference organised by the Jamaat-e-Islami. Describing the act as "un-Islamic" at the conference in Lahore, the religious groups decided to meet again in Islamabad on April 2 to decide their course of action.
Raheela Khadim, chairperson of the Punjab Assembly's standing committee on gender mainstreaming, believes not just the law but the women supporting it are facing criticism.
"Women are usually snubbed in society and this attitude is present even in the upper echelons of the society. An example would be the criticism being faced publicly by women supporting the law," she said.
One of the women lawmakers behind the law, Uzma Bukhari, said the act is in no danger despite the growing opposition.
"There are so many contradictions in the concerns raised. There is no answer over which clause of the law is un-Islamic," said Bukhari, also chairperson of the standing committee on law and parliamentary affairs.
What is significant is that the law will protect aggrieved women from being forced out of their homes. Instead, the defendant can be made to leave the house for two days.
The law states anyone offering resistance to protection officers will be punished with a prison term of up to six months and a fine of up to Rs 500,000. Once a complaint is received, it will be included a database.
Filing a false complaint or levelling false accusations can be punished with up to three months in jail or a fine.
Shelter homes will be built for the protection of aggrieved women, and they will provide board and lodging to the victim and her children.
Religious leaders said it is "degrading" that defendants can be cuffed with GPS tracking bracelets on the orders of a court. Those attempting to remove or tamper with the bracelets will be jailed for up to a year and fined between Rs 50, 000 to Rs 200, 000.
Also, defendants will not be allowed to apply for an arms license or procure weapons, whereas weapons already registered in their name will have to be surrendered to court.


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Ed Sheeran has reached an agreement with two music producers who claimed that his song, "Photograph," was copied "note for note."
Martin Harrington and Thomas Leonard sued the British singer for $US20 million (£15.3 million). The composers said that "Photograph" was a "verbatim" copy of their composition, "Amazing," which was recorded and released by 2010 "X Factor" winner, Matt Cardle.
Cardle was not involved in the lawsuit.
The Hollywood Reporter said court papers were filed on Friday, dismissing the case with prejudice on the condition that a California federal court would retain jurisdiction to enforce the terms of an agreement.
Harrington and Leonard's lawyer Richard Busch told Sky News: "I can confirm the case has settled but cannot comment further."
You can listen to the two tracks under scrutiny back-to-back here:
'Amazing' — Matt Cardle:
'Photograph' — Ed Sheeran':
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PROCARE - Polyester Suture
Procare is the brand name of polyester sutures manufactured by Dolphin Sutures.
Polyester suture is a braided and coated suture (silicone) and is a non-absorbable suture composed of Polyethylene terephthalate fiber.
Polyester sutures have excellent tensile strength, soft and pliable with excellent braiding and are an excellent choice for cardiovascular and ophthalmic surgery. Polyester sutures are not subject to degradation and retain tensile strength indefinitely in vivo.
Polyester sutures are available in green and white colours.
- Polyester suture is a coated and braided non-absorbable surgical suture. Polyester sutures are available with silicone or PTFE coating (on demand only).
- Polyester sutures are available from U.S.P. size 5 to size 6-0. Sutures are available in green, white and black colours.
- Polyester sutures are composed of polyester which is a category of polymers which contain the ester functional group in their main chain.
- Polyester sutures are used for permanent, removable fixtures, cardiovascular surgery.
- Our Polyester sutures are coated with silicon which facilitates the easy passage through the tissues.
- Procare polyester sutures exhibit good knotting strength and secure knot placement.
- Procare polyester sutures are available with needles made from 300 series alloy steel for superior strength, sharpness and performance.
- Procare sutures are having excellent tensile strength and is ideal for cardiovascular surgery.
Procare® suture is made of fine filaments of polyethylene terephthalate fiber braided to produce suture that remains soft & pliable, coated with silicone. Procare® sutures are dyed with D&C Green No. 5, usfda approval number §74.1205. The suture is also available in undyed form.
Procare® sutures are available in range of gauge sizes and lengths, non needled or attached to stainless steel needles of varying types, sizes and shapes. The needles are attached permanently to the suture. Entire details of the product range are available in the catalogue. Procare® complies with the requirements of the United States Pharmacopoeia monograph for "Non-absorbable surgical suture".
Procare® sutures are intended for use in orthopaedic, general and ophthalmic surgery.
The suture should be selected and implanted depending on patient's condition, surgical experience, surgical technique, and wound size. Normally the skin sutures are removed within 30 days depending on wound condition. The decision of doctor is final in removing the skin sutures.
Procure sutures elicit a minimal acute inflammatory reaction in tissues, followed by a gradual encapsulation of the sutures by fibrous connective tissues. Implantation studies in animals have shown no meaningful decline in the tensile strength over a period of time. Polyester sutures are pharmacologically inactive.
Adverse reactions associated with the use of Procare® Suture include transitory local irritation at the wound site or transitory inflammatory foreign body response. Like all foreign bodies Procare® may potentate an existing infection.
The use of this suture is contraindicated in patients with known sensitivities or allergies to polyester and silicone.
- Surgeons should be familiar with surgical procedures and techniques involving non-absorbable sutures before employing polyester suture for wound closure, as the risk of wound dehiscence may vary with the site of application and the suture material used.
- In surgery of the urinary or biliary tract, care should be taken to avoid prolonged contact of this or any other suture with salt solution, to prevent calculus formation.
- For single use only. Do not reuse, reprocess or re-sterilize. Reuse, reprocessing or re‐sterilization may compromise the structural integrity of the device and/ or lead to device failure which, in turn, may result in patient injury or illness.
- Reuse, reprocessing or re‐sterilization may also create a risk of contamination of the device and/or cause patient infection or cross‐infection, including, but not limited to, the transmission of infectious disease(s) from one patient to another.
- Contamination of the device may lead to injury or illness.
- Acceptable surgical practice should be followed for the management of contaminated or infected wounds.
- In handling this suture material, care should be taken to avoid damaging the surface of the material with surgical instruments as this could lead to fracture of the material in use.
- Avoid crushing or crimping damage due to surgical instruments such as forceps or needle holders.
- Adequate knot security requires the standard surgical technique of flat and square ties with additional throws as indicated by surgical circumstances and the experience of the surgeon.
- The use of addition throws is particularly appropriate when knotting Procare® sutures.
- Care should be taken to avoid damage while handling surgical needle, Grasp the needle in an area of one third (1/3) to one half (1/2) of the distance from the attachment end to the sharp point.
- Grasping in the sharp point area could impair the penetration performance and cause fracture of the needle.
- Grasping at the butt or attachment end could cause bending or breakage.
- Reshaping the needles may cause them to loose strength and make less resistant to bending and breaking.
- Users should exercise caution when handling surgical needles to avoid inadvertent needle stick injury.
- Discard the used needles appropriately.
Adverse reactions associated with the use of Procare® sutures include transitory local irritation at the wound site or transitory inflammatory foreign body response. Like all foreign bodies Procare® sutures may potentate an existing infection.
Procare® sutures are sterilized by ethylene oxide. Do not re-sterilize! Do not use if package is opened or damaged! Discard opened unused sutures.
Recommended storage condition 10oC-35°C, away from moisture and direct heat. Do not use after expiry date.
Discard used sutures and needles contaminated with blood in the container meant infectious waste. Unused expired pouches should be incinerated.
- Polyester sutures are individually packed in a primary medical grade paper folder
- Individually packed sutures are then packed in a tear-open or peel-open aluminum foil
- Aluminum foils are further packed in a secondary medical grade paper pouch laminated with polyester laminated poly film
- Sutures are further packed in small cartons made from premium 320 GSM Cyber XLPac in 12 suture pack
- Boxes are further laminated in tamper proof film to protect it from dirt/dust
- Further, the sutures are packed in an export worthy 7 ply master carton which can accommodate 100 boxes ( 70 x 30 x 30 cms) - weighing up to 9 to 10kg and 200 boxes ( 70 x 29 x 59 cms) - weighing up to 18kg


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Advantages of an Online Cannabis Dispensary
Since the legalization of cannabis in many states, many people are using it for recreational and medical purposes. The huge demand for cannabis cannot be sustained by the local cannabis dispensaries available, and therefore, some people are likely to miss their doses. Nowadays, if there is no local dispensary near you, you should not worry because you can still purchase cannabis from an online dispensary. Nowadays, there are many online cannabis dispensaries compared to brick and mortar dispensaries. Many benefits are associated with buying cannabis from an online dispensary, and this article highlights some of them you should know.
Buying cannabis is hassle-free. Imagine walking a long distance looking for a cannabis dispensary when you are sick or fatigued. You might be forced to move from one dispensary to another in search of your favorite cannabis products, but you do not need to go through that hassle when you can purchase cannabis online at the comfort of your home. That is not the case when you choose to buy cannabis from an online dispensary because you will check the website from wherever you are and make an order without moving a limb. It is not a reason to say that you skipped your dose because the dispensary was closed or you were tired to go to the dispensary.
There is a wide range of cannabis varieties, and you can buy the quantity you want. A majority of local dispensaries stock cannabis varieties according to the demands of the locals. That means that if you have a different preference, you will not find it at a local dispensary. Online cannabis dispensaries cater to the needs of a broad market, and thus, they will have almost all the strains. Further, the dispensaries are well-stocked with enough quantities to supply you if you purchase in bulk. Even if you do not find a strain you want on a website, it is easy to move to another website and get it.
You will get the best prices on online dispensaries. Everyone is conscious about prices when they want to buy a product, and they are always looking for the best deals. The reason for the high price of cannabis in local dispensaries is that they incur a lot of running costs such as rent and wages. Online dispensaries have a low maintenance cost, and that makes the prices of cannabis affordable. Further, you can check out for discounts and exclusive offer that can significantly reduce the total amount you pay for cannabis.
You have sufficient details to inform your decision. There is no room for confusion when you are buying cannabis online because the information is available. Online cannabis dispensaries avail adequate information to guide buyers. For example, pictures are available for easy identification and accompanying details about usage and dosage. It is easy to choose the cannabis product you want so that you do not regret afterward.
The Beginners Guide To Dispensaries (Chapter 1)


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GA-K8VT800M (rev. 1.0)
- Supports new generation AMD Athlon™64 processors
- Enhances system performance with DDR 400 memory
- Integrated Serial-ATA interface with RAID 0,1 function
- Integrated high quality 6-channel AC'97 audio with Jack-Sensing
- Integrated 10/100Mb Ethernet controller
- Provides 8 USB 2.0 ports for high-speed connectivity
IntroductionSupporting the revolutionary AMD AthlonTM64 processor, GA-K8VT800M delivers the most cost effective platform and brings new levels of performance and features to the desktop systems. The brand new AMD AthlonTM64 processor is furnished with unprecedented framework consisted of AMD's 64-bit computing platform, HyperTransport Technology, and the CPU-integrated memory controller to boost the overall performance. Accompanied with the innovative designs of AthlonTM64, the advanced VIA K8T800 chipset and Gigabyte's unique technology also contribute to the functionality and stability of this platform. The high speed Fast Ethernet interface is equipped for establishing the efficient broadband connection to the internet. With up to 150MB/s data transfer rate, the Serial ATA interface provides superior input/output performance and data protection. GA-K8VT800M is the best choice for multi-functional system used in home and office environment.
The Very First AMD Certified Cool'n'Quiet supporting Motherboardthe k8vt800m is the very first motherboard certified by amd for supporting its cool'n'quiet feature on the athlon64. with dynamic cpu voltage control, this platform dramatically reduces processor power consumption without degrading system performance. as well, throttling of the system fans allow for a cooler and quieter pc, resulting in decreased noise level for a more comfortable work or educational environment. please update the latest processor driver and motherboard bios before enabling the cool'n'quiet function.
download the processor's driver
AMD AthlonTM64 Computing PlatformPowered by VIA K8T800 chipset, this platform supports the brand new 8th generation AMD AthlonTM64 processor to deliver a high performance platform with dual support for 32-bit applications and increasing 64-bit computing needs
HyperTransportTM technologyA high-speed, low latency, point-to-point link designed to provide excellent interconnect for computation and networking. This Technology not only provides more bandwidth but also reduces the I/O bottlenecks and, consequently, greatly enhances the system performance.
Integrated DDR memory controllerThe AMD AthlonTM 64 processor improves the memory performance by integrating a DDR memory controller into the processor. By running at the processor's core frequency, an integrated memory controller greatly increases bandwidth directly available to the processor at significantly reduced latencies
Superb bandwidth AGP 8X graphics interfaceFeaturing AGP 8x (AGP 3.0) the new generation VGA interface specification, this platform delivers enhanced graphics performance with high bandwidth up to 2.12GB/s. Allowing users to have a more realistic graphics experiences while gaming or movie watching.
Ethernet 10/100Mb LAN Network ConnectionEthernet 10/100Mb LAN Network Connection Provides high-quality 10/100 Ethernet performance for value-minded users who need straight forward network connectivity. Ensure a high-speed, stable solution for new broadband era.
Serial ATA with RAID 0, 1 functionSerial ATA is the revolutionary ATA interface that provides scalable performance for IDE device. With up to 150MB/s data transfer rate, Serial ATA is faster than current Parallel ATA and delivers superior input/output performance. In addition, the Serial ATA interface is furnished with RAID 0,1 function for extra performance enhancement and data protection
6-Channel Audio with Jack Sensing SupportUsers can experience the 3D surround sound through integrated 6-channel audio. It fulfills the requirements for a variety of audio applications, such as MP3 or Audio CD playback, DVD movies and gaming. With Jack-Sensing feature users won't have to worry about how to install audio devices correctly
Norton Internet SecurityTM IncludedNorton Internet SecurityTM 2004 is the essential protection from viruses, hackers, and privacy threats. It protects user during the online activities such as e-mailing, shopping, banking, and game playing.
* The entire materials provided herein are for reference only. GIGABYTE reserves the right to modify or revise the content at anytime without prior notice.
* Advertised performance is based on maximum theoretical interface values from respective Chipset vendors or organization who defined the interface specification. Actual performance may vary by system configuration.
* All trademarks and logos are the properties of their respective holders.
* Due to standard PC architecture, a certain amount of memory is reserved for system usage and therefore the actual memory size is less than the stated amount.
* Advertised performance is based on maximum theoretical interface values from respective Chipset vendors or organization who defined the interface specification. Actual performance may vary by system configuration.
* All trademarks and logos are the properties of their respective holders.
* Due to standard PC architecture, a certain amount of memory is reserved for system usage and therefore the actual memory size is less than the stated amount.


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Masahiko Sugimoto, Mineo Kondo, Yoko Yoshida, Hitomi Tanimoto, Ryohei Nakamura, Hiroyoshi Hidaka; Therapeutic potential of a novel isoquinoline sulfonamide derivative with protein kinase inhibition function, H-1337, in wet AMD. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):150.
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Exudative age-related macular degeneration (wet AMD) causes vision loss due to choroidal neovascularization (CNV). Here, we investigated the potential of a novel isoquinoline sulfonamide derivative, H-1337, and its main metabolite (H-1337M1), in ex vivo and an experimental CNV model as a potential therapeutic agent for wet AMD.
H-1337M1 was obtained from incubation of H-1337 with rabbit liver S9 fraction. ARPE-19 cells were pretreated with H-1337 or H-1337 M1 (1 μM for 25 h) and vascular endothelial growth factor (VEGF) concentration in culture supernatant was measured using ELISA. Cell migration was also assessed by wound healing assay. Cell proliferation was assessed by Cell Counting Kit-8 assay under same condition for human retinal microvascular endothelial cells (hRMECs) and human umbilical vascular endothelial cells (HUVEC). Effects of H-1337M1 on CNV were investigated in a rat laser-induced CNV model (6- to 10-week-old Brown Norway rats). After laser photocoagulation, H-1337M1 (intravitreal injections, 15 ng/eye, day 0 and day 7) was administered. Fluorescein angiography (FA) was performed after 2 wks and signal intensities in each laser spot were evaluated using Image J software.
Both H-1337 and H-1337M1 significantly reduced VEGF secretion by 28% and 38%, respectively (p < 0.01 compared with vehicle) and also inhibited cell proliferation of hRMECs (H-1337: with an IC50 of 4.3 μM, H-1337M1: with an IC50 of 4.4 μM) and HUVEC (H-1337: with an IC50 of 3.7 μM, H-1337M1: with an IC50 of 9.2 μM). Cell migration was significantly inhibited by H-1337 (at 30 μM, p < 0.001 compared with vehicle) and H-1337M1 (at 10 μM, p < 0.001 compared with vehicle). The intensities of FA leakage from CNV were also significantly reduced in H-1337M1-treated rats by 67% (p < 0.05 compared with vehicle).
H-1337 and H-1337M1 treatment has the potential to become a novel therapeutic strategy for wet AMD.
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