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"I wish that I grew up in a household where I was taught nutrition and basic cooking technique," says Bruce Kalman.
The chef, who opened Union in Pasadena last year and is set to debut Knead & Co. Pasta Bar + Market in Grand Central Market later this year, is making up for lost time by schooling a new generation on food-savvy practices through Common Threads. The organization, which currently operates in Chicago, Washington D.C., Miami, and here in Los Angeles, provides hands-on cooking classes from professional chefs to low-income children and their families with the aim of helping to foster healthier lifestyles in underserved communities.
"I believe that teaching the next generation back-to-basics food preparation—pickling, canning, etc.—and equipping them with fundamental skills makes cooking fun and not so intimidating," says Kalman. "Ultimately, organizations like Common Threads are so important because they provide a platform for chefs like myself to educate kids on sustainability and how to make the best use of what is available to them and waste nothing."
This Thursday, the rest of us can get in on the learning, too. Kalman, along with James Beard Awards-nominated pastry chef Hedy Goldsmith (formerly of Michael's Genuine Food & Drink in Miami) and Common Threads instructor/ambassador Chef Lovely, will be hosting a class called Preserving Summer. Putting the focus on reducing food waste and increasing nutrition, the one-night course will cover simple pasta sauce preparation and jarring. Plus—and if you've ever had it then you know this is big—a demo on how to make Kalman's delicious pickled giardiniere. Goldsmith will show guests how to pickle stone fruit as well as make a strawberry basil consommé and meyer lemon confit.
Even better is that attendees will get to enjoy the sauce served with Kalman's housemade spelt cavatelli, giardiniere with fresh bread and butter, and all of Goldsmith's desserts.
Tickets are $90. All proceeds go to Common Threads.
Preserving Summer will take place this Thursday, September 24 at New School of Cooking, 8690 W Washington Blvd, Culver City, 310-842-9702. Class begins at 6:30 pm. Register online at www.newschoolofcooking.com.


text: Friends! Please check out my impassioned appeal to YOU to begin a daily practice of meditation! Those who know me, know that I am passionate about peace. It's something that has consumed me for the last six years as I searched the world over looking for answers. And while my outward search has bore much fruit with many answers revealing themselves to me, it in my inward search and cultivation of peace within that has truly been the most remarkable. Meditation allows us to find that, to feel balanced, tap into the infinite love that surrounds us and connect with our inner light that illuminates the path back home. Lots of love and peace for you all! xoxo

subset: commoncrawl


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Federal government officials avoided immediately disclosing just how severe the government employee data hack was by defining it as two distinct breaches, according to people familiar with the matter, in an incident that underscores the tensions within the government over what officials have described as one of the worst data breaches of U.S. data.
The FBI strongly suspects the Chinese were behind the hack of Office of Personnel Management databases, and those hackers accessed not only personnel files but sensitive security clearance forms, which contain information that foreign intelligence agencies could use to target espionage operations, according to officials. Chinese officials maintain that they weren't involved.
The administration disclosed the breach of personnel files on June 4th but not the security clearance theft. The security theft was disclosed a week later, but investigators probing the theft already knew about it.
OPM Director Katherine Archuleta on Wednesday said her agency is investigating whether up to 18 million unique Social Security numbers were stolen as part of the cyber attack, though she cautioned that the numbers were unverified and preliminary.
Her statement was made during testimony to the House Oversight Committee. Lawmakers have accused OPM of not providing enough information about a breach, or perhaps series of breaches, striking OPM in recent months and stealing troves of personnel records.
Ms. Archuleta said she believes an estimated 4.2 million personnel records of current and former government employees were stolen as part of one breach, but she said the estimates were much less precise on the hack of background check investigations that took place over a number of years.
Even before the OPM announced it had been hacked, officials at the office denied to The Wall Street Journal that security clearance forms were taken. A day after the public announcement, they denied it again, with an OPM spokesman saying there was "no evidence to suggest that information other than what is normally found in a personnel file has been exposed.''
Yet by that time, the FBI already knew, and told OPM, that the security clearance forms had in fact been accessed, these officials said.
The same day as the OPM denial, Janet Napolitano, president of the University of California system, sent a letter to university officials saying anyone with a security clearance, including people who have never worked for the federal government, could be affected by the hack. Ms. Napolitano is a former head of the Department of Homeland Security.
The FBI, which is investigating the OPM hack, didn't define it the same way. When responding to computer attacks on companies or government agencies, the FBI leaves it to the victim agency to say publicly and to its employees what was taken. In the case of the OPM hack, however, FBI officials, including the director, James Comey, also had to speak to lawmakers about the incident, and he didn't discuss the incident in the "two breaches'' terms that OPM used, according to people familiar with the matter.
An OPM spokeswoman said the agency had been "completely consistent'' in its accounting of the data breach.
"As the investigation into the personnel records intrusion continued, it was discovered that OPM systems containing information related to the background investigations of current, former and prospective federal government employees, and those for whom a federal background investigation was conducted, may also have been compromised. We notified Congress of this intrusion as well.''
Some officials defended the White House and OPM categorization of the breach, saying they were following the internal decision-making process, which culminated in a June 8 finding by the National Security Council that they had high confidence the security clearance forms had been accessed. Four days later, the administration announced security clearance forms had, in fact, been accessed by the hackers.
Melanie Dougherty Thomas, who advises companies dealing with computer breaches, said deciding what to say about a breach—and when—is critical. "The general public understands there are breaches all the time. If you wait too long, you give the perception you're trying to hide the facts, and that to people is unforgivable. The issue of timing is the most delicate part of breach response.''
Ms. Archuleta said OPM and other agencies are looking through the files to try to tabulate a more precise number of records that were stolen. She said the numbers could be less than 18 million, as some of the Social Security numbers could have been duplicates from other forms. But, she warned, the number of people whose personal information was stolen could also grow.
"It may well increase from these initial reports," she said.


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2000: My Day
2001: An "Art-ful" Day
2002: Nice Weather for Ducks
2003: Clear Conscience
2004: Is Alzheimers Contagious?
2005: The Long Commute
2006: Moving On
2007: Back at the Beginning Again
Books Read in 2008
12 years...
My Favorite
Video Blogs
at these videos!
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21 May 2008
Just look at that. Isn't that weird in a very cool-weird kind of way? This is from The Fretting Zoo, which you should be checking every day, and if you're not--why not?
This is the kind of creativity that could produce great novels, great flights of fantasy of the kind I can't even imagine. A hatch back full of lentils? The square root of pudding is milk? The Salvador Dali allusions? Who thinks up these things?
This is the kind of thing that would never come from my brain and definitely not onto any screen. The limits of my creativity stop at sites like this:
Don't send a lame eCard. Try JibJab Sendables!
My own personal satisfaction is when I've written a well-crafted sentence or paragraph. I just ended my review of Streetcar Named Desire like this:
Now that tickles me. That is something I am capable of doing and when I hit it squarely on the mark, I'm very happy with it.
This evening I attended a meeting of the Davis Community Network board and found myself volunteering to be a "tech specialist" (or some such thing) for one of the city's non-profit groups about to learn all the tools available to them through DCN. Not sure I'm up to the job, but one thing is for certain: I will learn a lot trying to stay ahead of the people I'm supposed to be the "expert" for!
On the way home, I had KGO, San Francisco's talk radio station, on in the car and heard the tail end of a conversation with a woman who stated, several times that she was going to be pissed if Hillary didn't get the nomination. Her reason was that she herself had been in a male-dominated profession all of her life and had been subjected to sexual discrimination all of her life and if Hillary doesn't win it will be because the nomination would have been stolen from her by men who didn't want a woman in the White House. She had nothing to say about Hillary's policies, her campaign promises or anything except that she was a woman and, dammit, it was time for a woman in the White House.
While I certainly agree that it is way past time for this country to have a female president and that Hillary is well qualified for the position, to vote for someone only because they are female and because you yourself and countless other women have been subject to sexual discrimination makes about as much sense as voting for Obama because he's black and it's time for a black man to be president.
Another reason for voting for Hillary that I have heard from at least one person whose opinion I normally value is that if Hillary wins, it means Bill will be back in the White House and if a crisis comes up and Hillary has problems, Bill will be there to help her.
That, to me, is a more sexist reason to vote for Hillary than just because it's time for women to rise up out of repression. It says to me "I'm not convinced that Hillary can do the job, but she'll have a strong man to back her up so it will be OK."
Vote for a candidate because he or she inspires you or meets your own vision of what direction the country should go in, or because he or she is the best person you feel can get us out of this quagmire that we are in, but to vote for someone based on your own sexual repression, or because of the color of their skin or because it will get Bill back in the White House again is just a dumb reason to support a candidate.
In my humble opinion.
Yummm...fresh cherries from the farmers market
MILES TO NOWHERE: 40.5 miles
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Louis Wilfred "Lou" Hanlon was born in Brooklyn, New York on October 12, 1882, according to his World War I and II draft cards; his full name is from Who's Who in American Art, Volume 2 (1938). In the 1900 U.S. Federal Census, he was the oldest of five children born to Michael and Jennie. They lived in Brooklyn at 139 Cumberland Street. His father was a printer and he was a designer. The date of his move to Pennsylvania is not known. Who's Who said he was a pupil of the Pennsylvania Academy of the Fine Arts, Drexel Institute, and the Pennsylvania Museum and School of Industrial Art.
In 1910 Hanlon lived in Aldan, Pennsylvania on Providence Road, just west of Philadelphia. He was a newspaper artist. He signed his World War I draft card on September 12, 1918. He lived in Philadelphia at 1022 Walnut. His occupation was newspaper artist at the Public Ledger. His nearest relative was his wife Anna. He was described as medium height and build with brown eyes and hair.
Brooklyn Daily Eagle 4/4/1920
The 1920 census recorded the couple in Philadelphia at 277 Eleventh Street. He continued as a newspaper artist. In the Brooklyn Daily Eagle, he followed Charles D. Mitchell on Follies of the Passing Show, starting on April 4, 1920. The New York Times, May 6, 1954, obituary said, "…Mr. Hanlon had worked for The New York Journal, The Chicago Tribune, The Philadelphia Ledger and Philadelphia North American." A 1924 issue of Printers' Ink reported that he joined The Ben Dale Company, advertising art, in New York. According to the Times, he was an original staff member of The New York Daily Mirror, which he joined in 1924.
According to the 1930 census, he lived in Richmond Hill, Queens, New York at 90-06 107 Street. The newspaper artist had married when he was 36 years old. His daughter, Cecelia, was eight years old. In November 1935, a Society of Illustrators benefit show offended a few members in the audience, and five artist's models were arrested. Hanlon was among the group of six illustrators who appeared in court. In the mid-1930s he produced The G-Man.
On April 25, 1942, he signed his World War II draft cards. He remained in Richmond Hill at a different address, 86-31 105 Street. He worked for the Daily Mirror. His description was five feet seven-and-a-half inches, 150 pounds, with brown eyes and gray hair. In March 1946, he was a member of the National Cartoonists Society.
Hanlon passed away May 5, 1954, in New York City. The Times said he died "…of a heart ailment. He was a charter member of the Society of Illustrators and a member of the Silurians, a society of old-time newspaper men; the Philadelphia Pen and Pencil, and the Circus Saints and Sinners. Mr. Hanlon was an amateur astronomer and actor and an authority on Shakespeare and Gilbert and Sullivan." He was buried at the Saint John Cemetery in Middle Village, New York.


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The news about the coronavirus appears to get darker every day, and top scientists are cautioning people not to be overly optimistic that a vaccine is imminent.
The number of global cases has passed 10 million and the number of deaths has passed 500,000, according to Johns Hopkins University.
The World Health Organization says the number of new cases set another daily record Sunday – 189,000 — led by Brazil's 47,000 cases in a 24-hour period.
Many health experts say the actual number of cases around the word may be much more than the reported numbers, suspecting some countries of underreporting their COVID-19 statistics.
As many as 15 governments and medical laboratories are making a serious effort to develop a coronavirus vaccine with the first widespread trials expected to begin next month in the United States.
British researchers have said they plan to test a vaccine in Brazil in August.
The top U.S. infectious disease expert, Dr. Anthony Fauci, has said a vaccine could be available as soon as the end of the year. But he says while he is optimistic, he told The Associated Press, "We've been burned before. This isn't a race of who gets there first. This is, get as many approved, safe and effective vaccines as you possibly can."
Fauci added that researchers are going to have to be flexible enough to test vaccines in multiple sites and be ready to move as the virus moves.
"Nothing is going to be easy," he said.
A vaccine can take decades before it is proved to be safe and effective, and some medical experts say many companies will not even consider developing a treatment for a disease unless it can make a profit.
A global vaccine fundraising event that featured entertainers Miley Cyrus, Justin Bieber and Usher, among others, raised nearly $7 billion in pledges from the EU, United States, and elsewhere Saturday.
The money is aimed at ensuring a vaccine is available to everyone when it is ready.
"If and when an effective vaccine is found, then we as world leaders have moral duty to ensure that it is truly available to all," British Prime Minister Boris Johnson said.
He was joined by French President Emmanuel Macron who said, "Let's refuse an every-man-for-himself approach, let's continue to move forward together."
In the United States, which leads the world in the number of coronavirus cases and deaths, some states are setting daily records.
Some of these states, especially in the West and South, are finding themselves having to reimpose lockdowns and social distancing rules after easing them in the past weeks.
Florida Governor Ron DeSantis announced Sunday that he is again closing beaches in his state, blaming young people who are balking at wearing masks and practicing social distancing for driving the surge in new cases.
State officials have also put the brakes on alcohol consumption at bars because of what DeSantis calls "widespread noncompliance."
"It has invariably been because they packed so many people in and created a type of environment that we are trying to avoid. Caution was thrown to the wind and so we are where we are," the governor said.
The governors of Texas and California have also closed many bars, with Texas' Greg Abbott saying "COVID-19 has taken a very swift and very dangerous turn in Texas over just the past few weeks."
In California, Governor Gavin Newsom closed bars in seven counties that had reopened and urged those in eight more counties to close also.
Washington Governor Jay Inslee has suspended the fourth phase of his state's reopening plans. The northwestern U.S. state reported 3,180 new cases in the last week, a figure approaching what the state saw during the height of the outbreak in March.
In South Africa, Health Minister Zweli Mkhize has warned hospitals that they could be pushed to their limits because of a jump in new cases after many offices, factories and stores have reopened.
Workers at six Amazon warehouses in Germany say they will go on strike Monday because of concerns over employees testing positive for COVID-19.
A representative for the Amazon employees labor union says as many as 40 have been infected and accuses the company of putting profits ahead of safety.
Amazon denies the allegation and says it has invested billions to protect its workers all over the world.
Germany is Amazon's biggest market after the United States.


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wikiHow is a "wiki," similar to Wikipedia, which means that many of our articles are co-written by multiple authors. To create this article, volunteer authors worked to edit and improve it over time.
wikiHow marks an article as reader-approved once it receives enough positive feedback. In this case, 94% of readers who voted found the article helpful, earning it our reader-approved status.
This article has been viewed 59,574 times.
Learn more...
If you are organized by nature, you have a gift that others may be willing to pay for. Getting rid of clutter and getting organized can be a big challenge to many people who lack organizing skills and are overwhelmed by the task. Offer your organizing services in the areas of home, garage and closet organization for a business that is fun and profitable.
1Research the industry and your local market. The National Association of Professional Organizers provides information on how to start a home organization business as well as lists of organizers in your area.[1] X Research source Check out what organizing services others are offering already to find a specialty with low competition. You could choose to specialize in a specific area, like garage, home office or closet organization.
2Volunteer your time to get experience and build a portfolio. If friends and family always ask you to help them get organized, offer your services for free, and be sure to take before and after photographs. Volunteer your services at local retirement homes and other agencies. This is a good way to get used to working with others, which is a lot different than doing organization projects in your own home.[2] X Research sourceAdvertisement
3Work on your business and interpersonal skills. Your volunteer work will uncover some areas you need to work on. In addition, learn to use a computer, keep records and basic budgeting and accounting skills.
4Join professional groups like the National Association of Professional Organizers and other smaller organizations. Read journals and books and take classes to learn how to start a home organization business and run it successfully.[3] X Research source
5Look for a job in an organizing related field. Working as an administrative assistant, event coordinator, or any job that requires organizing people and resources will lend credibility to your experience.
6Use the Internet to market and build your business. Blogs about organizing are very popular. Once you start a blog, comment on other blogs and participate in organizing challenges to get more traffic and show off your skills. Make some extra money by selling organizing products on your blog or website.[4] X Research source
7Offer virtual organizing services if you don't have time to work in homes while you are getting started. Have clients send photos and descriptions of their problem areas. Recommend steps to get the organizing projects done on their own, as well as organizing products to fit their needs and budget.
8Find reliable vendors of organizing products. Look for different alternatives to fit your clients' styles and budgets. Baskets, boxes, bins and files are just some of the products you will need. Seek wholesale opportunities that will give you enough stock for your projects as well as some items that you can sell at a profit. Develop a system for ordering supplies and equipment quickly as needed.
9Get certified by the National Association of Professional Organizers. You'll need to satisfy educational and work experience requirements and pay a fee. Membership benefits include training, resources, and listing in the directory.[5] X Research source
10Get advice about taxes, finances, insurance and business setup. Your local Small Business Administration office provides mentoring and advice.
Community Q&A
QuestionHow can I get insured and bonded?Community AnswerTo become bonded, you must first determine whether you need a surety or fidelity bond. The important difference is that surety bonds are required by a third party (usually the government) to protect itself or the public, and fidelity bonds are insurance for you or your business.
QuestionWhat is the average cost of a home organizer?Community AnswerIt depends on your area, their range of experience, and services offered. I would expect to pay at least $30 to $50 per hour though.
- ↑ https://www.napo.net/default.aspx
- ↑ https://www.entrepreneurshiplife.com/what-is-a-professional-organizer-and-how-can-you-become-one/
- ↑ https://www.peaceofmindorganizing.com/blog/are-you-interested-in-becoming-a-professional-organizer
- ↑ https://www.brit.co/how-to-get-into-professional-organizing/
- ↑ https://www.napo.net/page/BCPOboard
About This Article
Reader Success Stories
"It was amazing information."


text: CNN:It was a busy week for Facebook, which hit a major milestone, made fashion news and made some users uneasy about privacy again. As of October 4, one of every seven people on the planet are actively using Facebook each month. "Helping a billion people connect is amazing, humbling and by far the thing I am most proud of in my life," Zuckerberg told CNN Money.


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Well-labeled Colonial Revival table serving as fine example of picking prowess
QI found this occasional table at a garage sale for $25. I've seen similar ones selling for $200 at antique stores. It has two drawers that pull out with lion pulls, and two other false lion pulls on the side. The feet have brass "toes", and you can see the base is beautifully detailed. Some damage on the top, but I don't think I'll refinish.
Inside one drawer is a label that says "Fine Arts Furniture Co., Grand Rapids," but I can't find any information on that manufacturer.
Any comments on the possible value? Date of manufacture?
— Name withheld
A Your table is a Colonial Revival table in a combination of the drum table, introduced
around 1800 by Thomas Sheraton, and the traditional Colonial round lamp table. The vertical stripes in the mahogany veneer on the skirt and drawer fronts are a nice touch. The pedestal and Duncan Phyfe style legs are probably made of gum. The legs and urn pedestal are faithful Federal period stylistic elements, but the lion's head pulls are very much from the slightly later American Empire period.
This table was probably was made in the 1930s or 1940s. You did extremely well paying only $25 for this little gem. Even with some slight damage in the top, a well identified piece such as yours from a Grand Rapids company could command a retail price of between $200 and $300. Fine Arts Furniture Company was founded in Grand Rapids, Michigan, in 1925 and was in business until 1977.
Q When my husband brought in the mail one day it was raining and some of the mail got slightly damp. He spread it out on the foyer table and left it to dry. One of the pieces of mail was a magazine in a plastic wrapper with printing on it. The next day when I moved the magazine, I discovered the printing was now on my table. The table is a light oak color, and the red and black print definitely does not look good on it. I tried rubbing it with steel wool and paste wax, and then I tried a "finish restorer," but neither made any difference.
Is there a cure for this?
— D.M., via email
A You are the victim of solvent migration. This transfer effect also happens when a plastic table cloth is left on a lacquer finished table for a long time or when a vinyl notebook is left unattended on a desk top. Sometimes it even results from the "rubber" pads on the bottom of answering machines, calculators and compact stereo speakers.
The solvents in most vinyls and soft plastics are very similar to the solvents used in commercial furniture finishes, especially older ones. The newer water-based finishes are not quite so susceptible. These solvents have a tendency to migrate when in contact with a similar surface such as the finish on your foyer table. and sometimes when they migrate they take some color with them, as you found out.
Unfortunately, the color is now a part of the finish on your table. The only question is: How far did the color penetrate? If it didn't penetrate too far, a good furniture technician may be able to "re-amalgamate" the finish and remove just enough to get rid of the printing.
If that doesn't work, the piece will have to stripped entirely to remove it. Just hope the stain didn't penetrate into the wood itself. In that case, you would have to bleach the table top to even out the color.
Q I grew up with this desk chair. Me and my brother and sister sat on it to do our homework. I still have it. It is very hard wood and very uncomfortable. I still use it though. Can you tell me how old it is and if it has any value? The tag on the bottom reads "The B. L. Marble Chair Co., Bedford, Ohio USA, Golden Oak - No 2 Color, Leather - 659, Series - 4405." Thank you.
— T.T., via email
AThe B. L. Marble Chair Company was founded in 1894 in Bedford, Ohio, about 12 miles southeast of Cleveland. Apparently, the company manufactured commercial chairs in the early-to-mid 20th century. All the references I have found refer to chairs from the company going to libraries, social organizations and government entities. Your chair is a secretary or stenographer's chair and almost certainly had a loose cushion for the seat, but as you have found out, comfort in the office still had a long way to go.
Most chairs of this sort had a rubber bumper around the hardwood seat edge, and yours has a channel that may have held that bumper. Even though the color says "Golden Oak," I do not believe the chair is made of oak. It looks more like maple or birch with a stain over it. One of the photos showing the underside of the chair shows a dark stain drip along the back edge and on the bottom of the hip rest.
One more interesting thing about your chair: The mechanism underneath that supports the seat on top of the central stem appears to be made of wood and stained dark. I have never seen this and I have to believe it is a home repair job.
The chair appears to be from the 1940s and probably has little retail value (under $100) but probably lots of sentimental value to you and your siblings.


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Toyota has developed a concept of a flying vehicle that retracts its wings into the fuselage once it is on land. A patent filed by the company in 2014 revealed the way the vehicle would transform from a land vehicle to a flying vehicle and vice-versa. The flexible wings remain attached in a rear portion of the vehicle which has movable panels. The movable panels are hinged above the rooftop of the automotive. The wings are able to fold and unfold after the movable panel allows space into which wings can retract. There is also a possibility that the fuselage may be managed with the help of telescopic struts in order to adjust with the airflow characteristics when the vehicle is aloft in air.
Although other important descriptions like the kind of engine that would be used has not been described. However, a propeller mounted in the rear part of the vehicle can be seen. Features like a second propeller or a rudder that are required in flying vehicles are not marked in the diagrams. It is presumed that the functionalities would be carried out by ailerons or flaps present on foldable wings.
Interestingly there have been many great developments in the field of flying cars in past few years. AeroMobil, the Slovakian company has come up with three generations of an advanced flying car. While there have been reports of very advanced models being developed by German engineers. Google co-founder Larry Page has backed two flying car developers and patents of very advanced VTOL vehicle have already been filed by one of them.
AeroMobil's flying car also carries retractable wing system at a variable angle attack. This allows take-off within a short-distance. There is also provision of a resilient suspension that helps to take off from less smooth runways.
The companies funded by Larry Page show signs of tough competition with each other and are independently working on two flying car project.One of the companies Zee.aero has filed its patent on concept of a VTOL vehicle 'that can fit in the parking of a multiplex' while the other one Kitty Hawk is working to produce a quadcopter.
However, it may still be too soon to expect a flying vehicle to be launched in near future.


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Le Manoir du Rocher
Grand-mère, Québec
Le Manoir du Rocher
Grand-mère, Québec
In Shawinigan, there is a place for those who love thrills or simply for fun and fresh air. MAXIMUM AVENTURE offers you the rental of mountain bikes and snowmobiles on and off trails and many other motorized vehicles to devour our network of well-maintained trails that take you all over Quebec.
You can also rent quads, boats, spiders, or even drive a Mustang if you feel like it.
Maximum location
2850, Rue des Apprentis
Shawinigan, Qc, Canada
(877) 538-8899


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Local groundwater management agencies will need to collaboratively make decisions about the management actions their basin will collectively undertake in order to meet their sustainability goals under SGMA. Reaching these decisions will require local agencies to integrate a host of technical information into the decision-making process; develop clear and consistent criteria about the conditions under which they will implement management actions, who will be responsible for implementation, and how to fund them; and to establish a well-developed plan to engage and communicate with stakeholders throughout the decision-making process. Achieving these goals will not be easy and will require a long-term, strategic approach to the decision-making process.
Held in June 2016, this workshop focused on developing a comprehensive list of management actions that local agencies are likely to undertake during SGMA implementation and potential tools, approaches or technologies to support and communicate the decisions to undertake them.
This workshop is part of the Groundwater Data Workshop Series.


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Welcome to Friday Features, fortnightly posts highlighting a particular aspect of our current projects. And in this inaugural post, we'll be looking at Regency tales—retold!
Empire dresses, cravats, cotillions, and well-mannered conversations—what's not to love about the Regency era? In fact, we are so fond of the distinctive time period during 1811-1820, that we've sought to re-create the Regency in our current major project, Regency Love, a dynamic role-playing game that allows you to experience a multi-layered world, rich with characters, places, and, of course, stories.
The related perks aren't bad, either. One of the best bits about working on the game is the opportunity to immerse in the Regency world, guilt-free, because clearly, all those films and TV series we're watching are crucial to our research. The popcorn is compulsory, too, because, naturally, we'll need something to fuel our minds. And even if an adaptation is far removed from the Regency era, well… It's all about the story-telling, isn't it?
So here are some of our favourite Regency-related adaptations (compiled while calmly hiding our inner excitement):
- Pride and Prejudice (BBC, 1995): Yup, you probably saw this from a mile away. And yes, here's the obligatory mention: Mr Darcy's wet shirt.
- Emma (BBC, 2009): Emma is Samantha's favourite Austen novel, and this adaptation is sumptuous, playful, and vivacious.
- Persuasion (2007): This is Melody's favourite adaptation, thanks to Rupert Penry-Jones's amazing Captain Wentworth and Sally Hawkins's gentle Anne. The beautiful seaside scenes are worth a mention, too!
- Sense and Sensibility (1995): A wonderful cast, with Alan Rickman as a lovely and awkward Colonel Brandon.
- Clueless (1995): Emma, Beverly Hills, fin-de-siècle. Yes, please.
- The Lizzie Bennet Diaries (2012-3): A witty and interactive adaptation of Pride and Prejudice that utilises a variety of social media, and is set firmly in the early twenty-first century.
- Bright Star (2009): Keats's poetry in Ben Whishaw's voice? Epic win. The cinematography is stunning, too.
As you might imagine, the creation of this list involved a great deal of deliberating, pruning, and perhaps even re-watching. The things we do in the name of research, because, after all, it's all about respecting and loving the Regency!
What are some of your favourite Regency-related adaptations? We'd love to know what you love, so do give us a shout in the comments!


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Game 1: Tuesday, September 27th
Winning Pitcher: Aaron Sanchez
Sanchez struck out the first four batters he faced (and five of the first six). The Blue Jays quickly got a 2-0 lead when Ezequiel Carrera led off the first inning with a walk and Josh Donaldson homered to drive him in. The lone Baltimore run came in the 3rd when Mark Trumbo singled to cash in a J.J. Hardy double. Troy Tulowitzki prevented the inning from becoming bigger when, with two on and one out, he caught a Manny Machado line drive.
Then it was Carrera's turn to homer, his sixth of the season, in the bottom of that same inning. He got another chance to drive in a run when he came up in the 5th with Kevin Pillar on 2nd and one out. Pillar had singled, then moved over on a Darwin Barney sacrifice bunt. Carrera singled and Pillar scored. Carrera then scored when Edwin Encarnacion reached on a Manny Machado error. Carrera went 2-for-3 for the evening with a home run, a walk, two RBI, and three runs scored. The Jays had nine hits, seven of them off Kevin Gausman. Sanchez allowed one run on five hits and three walks in six innings. Joe Biagini came in for two scoreless innings and struck out two, then Roberto Osuna allowed two singles but got a double play to end the game.
Game 2: Wednesday, September 28th
Jays lose, 2-3
Starting Pitcher: Francisco Liriano
Losing Pitcher: Roberto Osuna (blown save)
The Blue Jays got a run in the first, with Ezequiel Carrera reaching on a Chris Davis error, scooting to third base on another error (this one a Chris Tillman pickoff attempt) and scoring on an Edwin Encarnacion sac fly. Another sac fly, off the bat of Kevin Pillar, scored another run in the 2nd. They had six hits off Chris Tillman in five and two thirds innings, then didn't get a single hit off the Orioles' bullpen.
Francisco Liriano kept the O's scoreless for his six and a third innings, and Brett Cecil finished the job in the 7th by stranding two singles. Liriano didn't allow a baserunner in the first three innings, nor in an 8-pitch 6th. He allowed six hits and one walk, struck out ten, and also stranded the bases loaded in the 5th. The first Orioles run came off Jason Grilli with two outs in the 8th – a solo Mark Trumbo homer. In the bottom of the 8th, the Jays loaded the bases when Josh Donaldson and Russell Martin were both hit with pitches, and Troy Tulowitzki walked. Then Melvin Upton, Jr. struck out to leave them there.
Osuna started the 9th with a one-run lead and gave up a single to Jonathan Schoop, then a pinch-hit home run to Hyun Soo Kim. Osuna's second blown save in the last week led to a one-run Orioles lead and, when the Jays went down on two strikeouts and a groundout in the bottom of the 9th, the loss.
Game 3: Thursday, September 29th
Jays lose, 0-4
Losing pitcher: Marcus Stroman
Ubaldo Jimenez only allowed one hit to the Blue Jays over 6.1 innings – a leadoff single to Ezequiel Carrera in the 1st inning. That was it, although they did get three walks off of him. Devon Travis – making his first start this series after being injured in the Yankee fight – walked to lead off the 3rd, but was eventually stranded at third base. Toronto had one baserunner between the 4th and the 7th.
Marcus Stroman got lucky in the 1st, stranding a pair of singles. He allowed the first run in the 3rd on a J.J. Hardy double and a Manny Machado sac fly, then another in the 4th on a Michael Bourn fourceout. The Orioles touched Stroman up for a run in each of the 7th and 8th innings, and he left with nobody out in the 8th. Aaron Loup got a strikeout, and Ryan Tepera pitched an inning and a third. Edwin Encarnacion doubled in the 9th (the third of three hits for Toronto) and advanced to third base on a balk, but was still there at the end of the game when Jose Bautista struck out and Russell Martin grounded out.
Overall notes:
With the Jays' loss on Thursday, the Red Sox have clinched the American League East championship. The Blue Jays will now have to battle it out with Baltimore for the Wild Card, with Detroit and Seattle also possibly being factors.
If they don't make the wild card, this is possibly the last home game for Edwin Encarnacion and Jose Bautista, as they are both free agents at the end of the season. This point was really driven home when, after being stranded on third in Thursday's loss, Encarnacion sat alone in the dugout looking out into the stadium before giving a poignant wave goodbye.
Weirdly Specific Record Alert:
- Game 2 was the 13th straight game where the starting pitcher allowed 2 or fewer ER, a record streak for the franchise
- It was also the 7th consecutive game where they starter allowed 1 or fewer ER, a first in team history
- Troy Tulowitzki's catch on Machado's line drive in Game 1 was a first for this season:
Similarly batted balls have gone for a hit 100% of the time this year. Literally the first time someone's made an out on a ball like that.
— Arden Zwelling (@ArdenZwelling) September 27, 2016
My favourite player(s) this series: Carrera
He rarely gets his due in this section, since he rarely starts games and often is used as a defensive replacement. But Ezequiel Carrera has been making the most of his opportunities recently. He hit a home run, but also went 5-for-10 (.500) in the series, scored 4 runs and had 2 RBI. Not bad at all for someone who was leading off as a replacement for the injured Devon Travis.
Where we are now:
Tied with Baltimore for the second place in the AL East, 5.0 games back of Boston, and tied for the Wild Card
The bad news is, they have no chance of overtaking the lead for the division, they need to play the division champs and win in order to make sure they're in the Wild Card game – and then they'll need to win the Wild Card game.
The good news is, their starting pitching continues to be good, they've won more games against the Red Sox than they've lost, and anything can happen on the last weekend of the year.
Follow me on Twitter: @JaysGirlEmily
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Mumbai, Nov.23 : The Central Bureau of investigation (CBI) on Monday sought an additional ten days remand for former Star TV CEO Peter Mukerjea, who has been charged with murder and criminal conspiracy in connection with the Sheena Bora murder case.
Rahul Mukerjea, son of Peter, had on Sunday defended his father and said he was certain of his father's innocence.
"See, I can't give reasons at the moment because I don't want to compromise the case that is being investigated. But, needless to say my father is innocent and I am pretty sure of that, in fact I am certain of that," Rahul had told media before meeting his father.
However, according to the chargesheet filed by the CBI, Rahul found Indrani Mukerjea (the prime accused) and Peter's initial responses to be evasive and contradictory, which prompted him to put them on record.
It was on the basis of Rahul's evidence that CBI arrested Peter.
Earlier, the CBI said that while it had earlier booked under several sections of the Indian Penal Code (IPC), he had also been additionally charged under Sections 302 and 364, and would be prosecuted accordingly. It said that four serious charges have been levelled against him.
The sensational chargesheet also stated that besides the financial dispute, the motive behind Sheena's murder could have been her 'relationship' with Rahul, which had irked Indrani.
The CBI alleged in court that Indrani and Peter hatched the murder plot in early 2012. Indrani returned to India on April 23, 2012 while Peter stayed back in the UK and returned on April 26, a day after the murder.
"Indrani had purchased a flat for Sheena in Delhi through a gift deed but she later terminated it after learning about Sheena's affair with Rahul. Sheena then allegedly started blackmailing Indrani, threatening to expose her before her social circuit as she had a birth certificate which proved that Indrani was her mother and not sister. Sheena demanded a three bedroom flat in Mumbai from Indrani.
This appeared to have irked Indrani, who then hatched a plan to kill Sheena along with (her former husband) Sanjeev Khanna. Peter played an active and crucial role in the case," stated the 1000-page CBI chargesheet. (ANI)


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Children's and Youth
1st Armagh Boys' Brigade
Why should I, (my son,) join 1st Armagh BB Company? The Object of the Boys' Brigade is:
The advancement of Christ's Kingdom among boys, and the promotion of habits of obedience, reverence, discipline, self respect and all that tends towards a true Christian manliness.
All our officers try to follow this object helping to ensure that the boys in our Company learn good habits and good standards that will prepare them for adulthood, and they will learn about God and what He has done for them through the death of his Son.
In today's world The Boys' Brigade is a place where you can find good influences, wholesome fun, true friendship and a real concern for your well-being. Any boy who is not involved in BB is missing out – so come along, get involved, and be part of the best youth organisation in the world.
ANCHOR BOYS (6-8 year old)
Who? Boys in Primary 2-4
Where? The Gosford Place Hall
What? Games, Bible stories, crafts, outings, and more games!
When? Tuesday 6.30 pm – 7.45 pm.
Contact: Elizabeth Barbour – 028 37524822
JUNIOR SECTION (8-11 year old)
Who? Boys in Primary 5-7
Where? The Memorial Halls
What? Games, Bible stories, badgework, competitions, nights away, and more games!
When? Tuesday 6.30 pm – 8.00 pm
Contact: Colin Berry – 028 37524428
COMPANY SECTION (11 – 18 year old)
Who? Boys Year 8 to 18 years old
Where? The Memorial Halls
What? Games, Bible Class, badgework, nights away, competitions, summer camp and a "Tuck Shop!"
When? Tuesday 8.00 pm – 10.00pm
Contact: Gordon Auld (Captain) 028 37522732
Company e-mail
Salt Cellar
Salt Cellar is a Christian Youth Club whose main aim is to help children and young people come to a saving personal faith in the Lord Jesus Christ. It is also a place where you can come and meet with your friends, and also make new friends. Age range is from P2 to 2nd year and we meet every Saturday night from 7pm to 8.45pm.
The bible talk remains the central point of the evening. The craft activities are very popular as well as all the games, sports and a fantastic tuck shop. We also organise trips away to different fun places. All the members really enjoy our nights at Salt Cellar, filled with great fun, in a safe environment.
The children all enjoy the different games and activities such as football, unihoc, dodge ball and some new games. The Wii, X Box and Playstation are all hugely popular.
Please continue to remember the work and witness of Salt Cellar in your prayers.
John 14:6
Jesus answered, "I am the way and the truth and the life. No one comes to the Father except through me."
For details tel Joan McDonald on 028 37522850
Sunday School
"Children of today are the Church of tomorrow."
The provision of Sunday School is part of our response to our baptismal vows where we promise to bring up our children in the worship of the church, so that they may come to know Jesus Christ as Lord and Saviour.
All children and young people from Primary 1 up to Year 10 are very welcome to Sunday School. We meet from 10.15 am (sharp) to 11.15 am each Sunday from September to June. We have a collection each week and on the 3rd Sunday of each month, we take a special collection for Pringle Home Orphanage in Jamaica.
We as teachers see parents as a vital part of our team by showing an interest in what your child has been taught. Above all, take time to read from the Bible and pray with and for your children. We want to support parents as they lovingly seek to make Christ known to their children, so if we can help in any way please do not hesitate to come and speak to us at any time.
Janet Auld
(028) 37522732
Sunday Worship Times
Sunday School – 10.15am
Morning Service – 11.30am
Prayer Meeting – 6.20pm (1st Sunday of Month 5.30pm)
Evening Service – 7.00pm (1st Sunday of Month 6.00pm)
What's On
|2* Morning Service at 11:30 am
|9* Morning Service at 11:30 am
|16* Morning Service at 11:30 am
|23* Morning Service at 11:30 am
|30* Morning Service at 11:30 am


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The 2016 Vancouver Christmas Market!
When you're up to your neck in assignments and don't have the time (or energy) to blog. #sadlife. Yea...these days (being finals season and all) I'm not very enthused, nor motivated, for that matter. Taking 5 courses definitely seemed more palpable at the beginning of the term (now, not so much.) I'm physically depleted, but still mentally SOUND.
"FINAL GRIND YO...you can make it!"
Well...one thing I can look forward to is: my upcoming trip to Cancun! I'm leaving on the 22nd so I'm going to be spending Christmas and New Years there! Exciting times..."in this lil ol' life of mine" (ok that rhyme really wasn't necessary Selina.) Why yes...referring to myself in the third person is a habit of mine...
Being that it is December going on 2017...holiday festivities are well underway already! As evidenced by our recent trip to the Vancouver Christmas Market last Saturday. We had a magical time (because c'mon...anything remotely Christmassy is magical.)
We got the Couples Combo, so we ended up saving how much? (Whatever, that's irrelevant.) The couples combo comes with 2 tickets, 2 carousel rides (which we have yet to use, because it was miserable outside) a gingerbread cookie (holla) a photo booth thingy, and (get this)...a seasonal pass! NICE.
The first place we hit up...BRAT HAUSSSS! (Man I love saying Haus. HAUS. There, I said it again.)
3.5/5 stars
Sans bun for me cause I'm all about avoiding dat gluten. And yes, Freybe is *certified* gluten-free! Anddd...it's nitrite free! (Something I always look for in processed meat.) But you know I still prefer BESTIE on Pender. Now that stuff is legit.
Jeremy's gluten-infested version of the DAS BRAT.
SECONDS YO, CAUSE WE RAVENOUS LIKE DAT. (Did you honestly think an entire pork hock would be enough to fill us up?!)
Whole Pork Hock (1 Order, Two Portions) Much to my dismay, it came with some gluten-ed bread (quit tempting me!)
4/5 stars
GOTTA GET DEM PROTEINS IN. (Do you even lift, BRUH?) Well, we definitely hit our protein benchmark that day by consuming an ENTIRE pork hock between the 2 of us. With copious amounts of relish to boot (man that stuff is addicting. And palate-cleansing.)
Nothing like a bit of fat to render that pork hock to perfection! And get some gristle stuck in your teeth while you're at it, because that means you're getting ALL UP IN THERE! Don't get me started on the PORK CRACKLING!
Yea, sexy or not, I'm gnawing at the bone.
Korean Pajeon (Vegan & Gluten-Free)
Some pajeon...because...WHY NOT?!! I'm always down for some Korean. This version just so happened to be potato-based, so NO FLOUR WHATSOEVER (which renders it gluten-free.) DUDE, I need the seafood version of this! It came with some applesauce on the side, which worked surprisingly well with the flavours!
Hurricane Potato (The ketchup version, cause I'm not keen on their flavoured powders.)
3/5 stars
WHAT IS DIS...THE RICHMOND NIGHT MARKET?! Not that I minded. Always up for some deep fried potato on a STICK!
Jeremy's hot chocolate, which he then proceeded to spill ALL OVER OUR UMBRELLA.
SOME APPLE CIDER...to defrost my very frozen hands.
I devoured the bar in its entirety, which rendered me HELLA HYPER for the remainder of the day. This one was pimped with Yerba Mate (if that isn't alluring, I don't know what is.)
BUNNY FRUIT SNACKS (and organic ones at that...cause we juvenile like dat.)
FOR SOME REASON I WAS EXPECTING THE COOKIE TO BE IN THE FORM OF A GINGERBREAD MAN. This'll do tho (in fact, I prefer this.) Oh, and they get points for being artisanal gingerbread cookies! Cookie aside...DAT DEPTH OF FIELD is *insert slang term here.* Good job iphone.
This ain't no farmer's market. That's soap YOOO. Soap made out of FRUIT EXTRACTS!


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What are the Best Apps you can use for an Android Box TV?
If you have an Android box and not using all its capabilities is like driving an amazing car and you don't use all its features.
the success of an operating system is its apps, and Android is a very successful OS. There are so many apps for this system, that the difficulty lies in the choice (whether it's free or paid).
The market share in Android streaming boxes is growing, and with it come more and more users of apps. With 2 billion monthly active users across all platforms, this makes the creation and optimization of apps for set-top boxes more probable.
YouTube | Netflix | Kodi | VLC | WeTV | Sling TV | Spotify | Google Chrome | Opera TV Browser


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Freeport may start Grasberg arbitration
Freeport-McMoRans Indonesian unit, PT Freeport Indonesia (FI), has submitted a notification to Indonesias mining ministry describing breaches and violations of its contract of work by the government. The dispute with the government has resulted in the company declaring force majeure at its Grasberg Copper Project in Papua province.
Freeport hopes to resolve the dispute with the government, but has also reserved the right to start arbitration against the government and to seek applicable damages.
The company warned of severe unfavourable consequences for all stakeholders, including the suspension of capital investments, a significant reduction in domestic purchases of goods and services, and job losses for contractors and workers as we are forced to adjust our business costs to match constrained production.
Freeport has been negotiating with the Indonesian government after halting its exports of copper concentrate due to new mining rules. Last Friday it said it could not meet contractual obligations for copper concentrate shipments from the giant mine following a five-week export stoppage.
On Saturday PT FI announced that its chief executive Chappy Hakim had resigned after the parent company had declared force majeure on copper concentrate shipments from Grasberg.
Chappy Hakim, a former air force chief, had only been in the job for a few months. Freeport Indonesia hoped he would be able to use his political connections to help the firm navigate its way through a period of regulatory uncertainty.
I have decided it is in the best interests of PT FI and my family to step down from my duties as president director while continuing to support the company in an advisory role, he said in a company statement.
The new rules require Freeport to pay taxes and royalties it was previously exempt from and divest up to 51% of its Indonesian unit, an increase from a previously set 30%. To date, it has divested 9.36%.
Mining Minister Ignasius Jonan on Saturday said Freeport had refused the governments offer of a six-month transition period in which the company can negotiate terms for its new mining permit.
Freeport could begin exporting again if it agreed to the transition period, he said. His ministry on Friday recommended that Freeport be allowed to export 1.1 million tonnes of copper concentrates until February 16, 2018.
The recommendation was conditional on Freeport accepting the special permit, said the parent companys spokesman Eric Kinneberg, repeating that the miner would only agree to a permit that provided the same fiscal and legal protection as currently.
Ignasius Jonan said that bringing the dispute to an arbitrator could hurt the relationship between the company and the government. But it would be a much better step rather than always using the issue of firing workers as a tool to pressure the government.


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PJ has been lethargic all week. We thought it was the heat and moved her upstairs. She perked up a bit - yesterday, we thought she was doing much better. I go to bed, have a very bad dream about angels that I'm NOT discussing, wake up and PJ's belly is swollen. She's also having problems walking/moving/breathing. We get her a vet appt. for three. By the time three rolls around, her breathing is worse and she's starting to turn blue. The vet recommended we put her down so we did. So, now ya know why I'm not very happy or pleasant at the moment. I don't deal with death or loss very well.
This may be morbid, but it's my attempt to cheer myself up - the IQ level of our house dropped today. We had more time with her than we expected, but she was a very good pet and I miss her incredibly.
So, here's to my little PJ (Precious Junior) - RIP: Goddess welcome her with open arms.


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"The projects will be jointly implemented with the help of Ministries of Science, Research and Technology of Iran and India," said Mohammad Reza Khalili, the Scientific Attaché of Iran in the Indian Subcontinent, adding "the implementation of this number of scientific projects between the two countries is unprecedented."
According to him, India's top educational institutions including technical institutes that have a good position in the world's scientific community, are collaborating with Iranian industrial universities in different scientific, research and educational fields.
Dr. Khalili also said that Iran has a lot of capabilities in nanotechnology, biotechnology and nuclear sciences, while India, in addition to its remarkable technological advances, also enjoys good experiences in commercializing knowledge and technology.
According to Iran's scientific attaché, the Ministry of Science, Research and Technology of Iran and India have recently signed a memorandum of understanding for a workshop on biotechnology.
He added that another Memorandum of Understanding was signed for a joint workshop on IT, which an announcement has been issued since January 1, 2018 calling for joint projects between the institutions and colleges of the two countries.
Dr. Khalili said that the announcement, which will continue until February 15, invites experts and scientists in the fields of biotechnology and water resources management to define joint projects of interest to both countries and submit them to the two ministries for approval and implementation. He went on to add "after the deadline, experts from both countries will hold a meeting in India to review and approve the projects, and of the projects received, 10 ones will be approved and will be implemented with the support of the two countries."


text: Supplementary MaterialsSupplementary date 41392_2019_82_MOESM1_ESM. seen in 57.6% (19/33, cohort 2) of HCC tissue by qRT-PCR, as well as the appearance of DKK1 was associated with tumor size (values of 0.05 were considered statistically significant. Results DKK1 expression is usually upregulated in human HCC tissues Immunohistochemistry revealed positive staining for the DKK1 protein in the cytoplasm of tumor cells. In general, DKK1 was weakly expressed (DKK1?, 14/22, 63.6%; DKK1+, 8/22, 36.4%) in 22 human cirrhotic tissues (Fig. 1a, b). In contrast, upregulated DKK1 expression (DKK1++ or +++) was observed in 48 of 53 human HCC tumor samples (90.6%) (Fig. 1c, d), while weak DKK1 expression (DKK1? or +) was found in the other five human HCC tumor samples (9.4%). qRT-PCR was performed to investigate the expression of DKK1 in 33 paired HCC and corresponding peritumoral tissues. As shown in Fig. ?Fig.1e,1e, significant upregulation of DKK1 was found in 57.6% (19/33, cohort 2) of the HCC tissue specimens compared with the corresponding peritumoral tissue specimens. These findings indicate that DKK1 may participate in human HCC progression. Open in a separate window Fig. 1 DKK1 expression is increased in HCC tissues. The expression of DKK1 in human liver tissues was evaluated by immunohistochemistry and qRT-PCR. The results revealed weak expression (DKK1? or +) in 22 of 22 human cirrhotic tissue samples (a, b). Upregulated DKK1 expression (DKK1++ or +++) was observed in 48 of 53 human HCC tumor samples (c, d). Scale bar?=?100?m. Thirty-three pairs of fresh HCC and corresponding peritumoral liver tissues were used for qRT-PCR analysis (e) HCC-related DKK1 expression is associated with tumor size and number As shown in Table ?Table1,1, qRT-PCR revealed that upregulated DKK1 expression was correlated with tumor size (value /th th rowspan="1″ colspan="1″ /th th rowspan="1″ colspan="1″ /th th rowspan="1″ colspan="1″ DKK1 br / up /th th rowspan="1″ colspan="1″ DKK1 br / down /th th rowspan="1″ colspan="1″ /th /thead Age (years)0.166?5017125? 501679Sex0.142?Male311714?Female220Capsular invasion0.296?Yes16115?No1789Portal vein tumor thrombi1.000?Yes1385?No20119Bile duct tumor thrombi0.424?Yes101?No321913Lymphatic metastasis1.000?Yes1165?Zero22139Metastasis0.620?Yes431?Zero291613Tumor size (cm)0.024?51138? 522166Tumor amount0.019?Single24177?Multiple927Tumor stage (UICC, 2010)0.238?We?+?II835?III?+?IV25169Histological grade0.531?G1?+?G21798?G3?+?G416106HBsAg1.000?Positive27522?Harmful1019Serum AFP (ng/ml)1.000?25642? 25271512CA199 (l/ml)0.698? 35963?35241311CA125 (l/ml)0.707? 351055?3523149 Open up in another window Compared via the chi-square test (Fishers exact test) Transfection of DKK1-shRNA inhibits the proliferation, colony-forming ability, cell cycle progression, and invasion of HepG2 and HUH-7 cells in vitro qRT-PCR and western blotting were performed to investigate the expression degrees of DKK1 in DKK1-short hairpin RNA (shRNA) HCC cells (HepG2 and HUH-7). As proven in Fig. 2a, b, DKK1 was effectively and suppressed by DKK1-shRNA in the evaluated HepG2 and HUH-7 cells functionally. To verify that DKK1 was silenced with the shRNA functionally, we used ELISA to gauge ORY-1001(trans) the appearance degrees of DKK1 in the supernatant of HCC cells. The ELISA outcomes revealed the fact that DKK1 level was reduced in the supernatant of cultured steady DKK1-shRNA HepG2 and HUH-7 cells (Supplementary Fig. 1a, b). We additional examined whether reduced DKK1 expression affected the natural actions of HUH-7 and HepG2 cells. The CCK-8 (Cell Keeping track of Package-8) assay outcomes uncovered that downregulation of DKK1 by DKK1-shRNA considerably inhibited the proliferation of HepG2 and HUH-7 cells (Fig. ?(Fig.2c).2c). The colony formation assay outcomes revealed that fewer colonies had been within DKK1-shRNA-treated HepG2 and HUH-7 cells than in the matching control cells (Fig. ?(Fig.2d).2d). Furthermore, the FACS analysis-based cell routine progression assay outcomes uncovered that DKK1 suppression reduced the amount of HepG2 and HUH-7 cells in the S stage (Fig. ?(Fig.2e).2e). The cell invasion assay outcomes showed that the amount of HepG2 and HUH-7 cells that migrated through the Transwell ORY-1001(trans) filtration system was markedly low in the DKK1-shRNA group than in the ORY-1001(trans) control group (Fig. ?(Fig.2f).2f). Collectively, these data indicate that suppression of DKK1 not only inhibits the proliferation but also decreases the invasion of HepG2 and HUH-7 cells in vitro. Open in a separate windows Fig. 2 Transfection of Rabbit polyclonal to AKR1A1 DKK1-shRNA suppresses the proliferation, colony-forming ability, cell cycle progression, and invasion of HepG2 and HUH-7 cells in vitro. Short hairpin RNA (shRNA)-DKK1 was transfected into HepG2 and HUH-7 cells. The stable cell lines were established after puromycin selection..


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First Lady Michelle Obama appeared in a sketch for College Humor with SNL's Jay Pharoah Thursday in an attempt to encourage teens to "make room" for college. The First Lady is no stranger to public service; in the past she has worked towards encouraging Americans to eat healthier and exercise more.
The lighthearted video has started a popular hashtag on twitter #FLOTUSBARS which feature users posting First-Lady-inspired verses.
OK, first things first I'll teach your brains Then I'm a start rocking fitbits and Bangs #FlotusBarspic.twitter.com/sogyydQCMF
— Denzel WASHEDington (@Sr_Gaines) December 10, 2015
It is very convenient timing that this message comes about on the same day that Justice Scalia has argued that black students cannot handle the rigors of top colleges. Coincidence?


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By: Kelly Smith, Marketing Director
I met with my financial advisor this week to take a hard look at where I currently stand in setting myself up for retirement. I'm 42 and would like to retire by age 65. That's 23 years to get this dialed in. That may seem like a lot of time, but when you have two kids who are growing like weeds and gray hair that seems to grow equally as fast as they do, I realize if I didn't look at this seriously now, I could really pay for it later.
Now, I know some of you may have this all figured out. And kudos to those of you future-minded people who have all your "i"s dotted and your "t"s crossed. I am not one of those people. I live in a more short-term, line-of-sight world. If it's not staring me in the face forcing a decision, then I I tend to put it off. I admittedly procrastinate.
But I also realize that when it comes to planning for retirement, procrastinators lose. Lose money that is. And since I don't want to live off my children's income when I'm retired and my 9-year-old daughter isn't volunteering to plan my retirement for me, I figured I'd better get my ducks in a row.
Planning for the future, whether it be 23 years from now or one year from now sometimes feels daunting. It takes a lot of thought, intention, and energy. And if you're at all like me, you want to do it right!
So when I sat down with my advisor the other day, my questions to him were simply, "Am I doing enough?" And if not, "what else can I do"? I was worried his answer would be more self-serving and he'd convince me I should put more money in the funds he supervises. But he didn't do that. He gave me honest direction I could understood in plain terms. He also told me that it wouldn't require significantly more out of my paycheck or less out of my lifestyle.
When he said that, I was all ears! He asked me about my debt and when I told him I just had a mortgage, he told me to pay it down faster. Yep. He told me to reduce any fixed debt ASAP. This does two things:
- It reduces the interest you pay on what you owe. The less time you owe money, whether it's a car loan, a credit card, or a mortgage, the less interest you pay, and
- your fixed debt disappears faster leaving you more time with less expenses.
My conversation with him is confirmed by others too. In a recent CNBC article, self-made millionaire David Bach agrees that:
Buying a home is the escalator to wealth in America. Homeownership can also help you retire early, that is, if you pay your mortgage off.
Bach suggests that homebuyers should, "Take out a 30-year mortgage, but with the intention of paying it off in 25, 20 or ideally, 15 years."
4 hacks to paying off your mortgage early
- Pay a little extra each month.
"…If you were paying $1,000 a month, now you're going to make $1,100 payments every month. Inform the bank that you are doing this and that you want the extra $100 a month to be applied to the principal (not the interest)." Bach explains that, "If you keep this up, you'll wind up paying off your 30-year mortgage in about 25 years. Increase your monthly payment by 20 percent, and you'll have that mortgage retired in about 22 years."
- Set up a bi-weekly payment. Rather than paying $1,000 a month, you'll pay $500 every two weeks. Doing this means you make 26 payments of $500/mo rather than 12 payments of $1,000. You end up paying an extra month each year, reducing your balance each year. You can use a bi-weekly accelerator calculator to plug-in your own numbers.
- Make extra payments. If you get a bonus, a monetary gift or inheritance, pay more down on your mortgage.
- If interest rates are more favorable now than when you purchased your home, you could consider refinancing to a shorter-term loan. You'll want to factor in fees and closing costs, however, before refinancing your loan.
After meeting with my trusted advisor and getting confirmation on this strategy from other resources, I called my lender and had them set up a biweekly payment schedule for me. I should be able to pay off my mortgage years before I'd planned meaning I might be able to take that around-the-world trip while I'm still active and healthy.
Bottom Line
Start thinking about retirement now. Whether you're 22 or 42, there are lots of ways to grow your money for the long-term. A mortgage is not a monthly expense like rent or bills. That money disappears as soon as you write the check. A mortgage is a wealth-building tool that, used wisely, can lead you on a faster path to retirement. Take it from my local financial advisor and from wealthy millionaires, consider either your first home purchase or paying off your mortgage early so that you can retire sooner with the money you will have saved!


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A recent study has shown that squirrels eating a large item of food are more vigilant, keeping an sharper eye out for predators than squirrels nibbling on tiny bits. Now, before you say "what an appalling waste of American taxpayer money!," please realize two things:
1) The study was done in Canada.
2) Understanding animal behavior is crucial to protecting the environment.
The researchers note that humans have a tendency to change habitats as we move into them. Some of those changes may make an animal feel threatened when it is not – or feel protected when it is actually vulnerable. Inappropriate behavior can lead to declining populations, upsetting the whole ecosystem.
So, be careful where you spread your birdseed. A squirrel's life could depend on it.


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In June 2018, the NSW Government announced funding of $740 million for the redevelopment of Liverpool Hospital into a world class health, research and education precinct (Liverpool Health and Academic Precinct – LHAP). The redevelopment will increase the inpatient bed numbers and significantly expand services.
The endorsed LHAP masterplan identified the need to demolish the existing P2 multi-storey car park to help realise efficiencies across the site in support of the campus masterplan. In March 2019, the NSW Premier Gladys Berejiklian announced $50 million towards 500 new parking spaces at Liverpool Hospital to help meet the projected growth associated with the redevelopment to 2026.
Project status
A tender process was undertaken and development application approval for the new multi-storey car park was granted in December 2020. ADCO Constructions Pty Ltd has now commenced work on the seven-storey car park, and construction will continue throughout 2021. The facility is anticipated to be operational in mid-2022.
The new multi-storey car park will be accessed via Burnside Drive and easily accessible from various hospital entrance/exit doors. The facility will be boom-gated with security lighting and CCTV to provide safe parking options, and will include the provision of solar panels to support improved sustainability for the broader Liverpool Health and Academic Precinct.
For information on the progress of works and any campus access impacts as a result of construction, visit our Precinct Updates page.
Check out this short video to learn more about the car park project.


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On Wednesday, May 10, 2017, 38 performing arts students from Broad Ripple Magnet High School for the Arts & Humanities, 15 adults including a few Broad Ripple teachers and other teachers from Indianapolis Public Schools, traveled to Chicago to attend the Broadway show Hamilton: An American Musical, written by Lin-Manuel Miranda about the life of Alexander Hamilton, US founding father and the first US Secretary of the Treasury. This critically acclaimed musical with great box office success has won 11 Tony Awards including Best Musical, a Grammy Award, and a Pulitzer Award for Drama.
Once the group arrived in Chicago, Broad Ripple Choral Director Denise R. Johnson asked for a show of hands of students who had never been to Chicago and four hands went up. Attendees spent time on Michigan Avenue and the Magnificent Mile. Then, they enjoyed Gino's East Chicago style deep-dish pizza before attending a matinee showing of Hamilton.
After the musical, one performing arts student stated, "I had listened to the soundtrack and knew all of the songs. I had pictured in my head how it would look on stage. This was better than anything I could have ever imagined. I'm just so glad our teacher planned this trip."
During her 17 year tenure at Broad Ripple, Ms. Johnson and has traveled out of the state with the choral music students, but this was the first time she took students out of Indiana to see a musical. Her goal for next year school is to travel with her students to New York. She believes this is possible with sponsorships and fundraising. To travel to Chicago, the trip was mostly funded by student-led fundraisers and some donations.
Students attending this magnet high school have interest in the performing, visual arts and media, while many pursue a major in college afterwards. Two former Broad Ripple students who are currently attending college in Chicago were able to attend the musical with the group. Sixty percent of students at Broad Ripple receive free and reduced lunch; without attending this school they might have never been able to travel to see professionals perform in the field that interests them.


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Premium Amusement Park & Funfair Ground Rides
Good amusement rides matter to your business success!
Amusement parks separate their rides into the children-friendly rides and the thrill rides. Of course, many of the thrill rides accommodate teenagers and younger children; however, this is not always the case as many thrill rides can be deemed somewhat dangerous for very young children. One of the most popular and extreme amusement park rides available is the jump and smile ride. This article will provide information about the jump and smile ride which can be used to ensure it meets one's specific amusement park needs.
Contrary to different amusement park rides, there is a variety of jump and smile rides available – the four arm ride, the six arm ride, the eight arm ride, and the twelve arm ride. Irrespective of the amount of arms, the jump and smile park ride presents with colored cabins attached to extended arms. The arms are created from fiber glass enforced plastic and are attached to the bottom of the cabin. The arms are connected to a central column and offer a rising and falling movement, in addition to full rotation of the ride.
As is mentioned above, the ride includes a rotating column placed on an engine that controls the rotation of the central axis. The cabins are attached to the end of the arms being placed atop the arm. This type of cabin does not present with straps, instead the rider is secured using an overhead bar similar to ferris wheels. While utilizing an engine, this ride is manually operated so that the speed can be adjusted accordingly.
One security issue that most people consider when riding the jump and smile is the lack of strapping on the cabin; however, the risk of injury is reduced as the rider is secured using an overhead bar which has additional locks on either side. Furthermore, manual operation allows for adjustment of the speed according to the riders' behavior.
As is mentioned above, the jump and smile ride is comprised of reinforced plastic which decreases the risk of breaking and increases durability. It is also very attractive with various colors and enjoyable music when in operation.
Unfortunately, this ride does present with certain disadvantages. One disadvantage is the lack of strapping for the rider; however, this is managed through additional security features. It should also be noted that this ride is not suitable for younger children and an age restriction is put into place. Finally, the lights can be unsuitable for individuals with photo-sensitive epilepsy.


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Virginia Tech-THOR
Virginia Tech proposed to develop THOR, a Tactical Hazardous Operations Robot, which will be state-of-the-art, light, agile and resilient with perception, planning and human interface technology that infers a human operator's intent, allowing seamless, intuitive control across the autonomy spectrum.
The team will emphasize three essential themes in developing THOR: hardware resilience, robust autonomy and intuitive operation.
SCHAFT Inc.- HRP-2 ROBOT
SCHAFT Inc. proposed a bipedal robot based on mature hardware and software designed for its existing HRP-2 robot.
SCHAFT Inc. proposed a bipedal robot based on mature hardware and software designed for its existing HRP-2 robot. SCHAFT will create an Intelligent Robot Kernel in which it will combine the necessary software modules for recognition, planning, motion generation, motion control and a user interface. The group will divide into three teams to execute the tasks: hardware design, software integration and scenario testing
Raytheon proposed to construct Guardian, a new, self-powered, lightweight, robust, dexterous humanoid robot that will build on the team's experience with human-scale exoskeletons.
The Guardian robot will expand its Exoskeleton (XOS) concept, introducing innovative technologies such as large range of motion, high specific torque/power actuators and a rapidly modulated fluid supply for overall power efficiency.
This articles published by DARPA Robotics Challenge Track A - Teams and Designs,Carnegie Mellon University (CMU) – National Robotics Engineering Center (NREC)


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"I would like to say thanks for making a filter that does what you claim. We run a DIRT northeast modified and I tell you what, it could not have been any dustier. We finished second 4-25-09 in part with your product. When Sunday morning rolled around, the first thing on the list was to see how well the filter worked. When removing the filters lid, it was hard to say what I was going to find. Where's the dust? Clean as a whistle. Thanks again for making a useful product available."
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On April 10, 2012, a visitor from Manchester, UK visited Ellis Island. It doesn't seem like an unusual event, but it was. This particular visitor had walked to Battery Park from San Francisco, Calif., in order to visit this icon symbol of immigration.
Twenty-six year-old Alan Slater had spent the previous 234 days walking the United States in order to raise money and awareness for Cancer Research UK. For Slater, whose life was affected when his grandfather was diagnosed with prostate cancer, the adventure was a way to honor his grandfather, get inspired in his life, and see the United States. He traveled California, Nevada, Utah, New Mexico, Oklahoma, Arkansas, Tennessee, Virginia, Washington DC, Pennsylvania and finally New York, where he ended his long journey at Ellis Island.
"I'm a lot like the people that first came to Ellis Island," he said. "I'm looking forward to what the future will bring now that my walk is over, but still a little anxious about it. I don't know what this new chapter has in store for me."
He began and ended his trip in national parks, starting in Golden Gate National Recreation Area, and along the way he visited Zion NP, Mesa Verde NP, Bryce Canyon NP, Glen Canyon- Escalante NRA, and Shiloh NMP. "The United States is incredibly diverse, crossing over into every new state is like crossing over in to a new world," Slater said.
While he found the grand western parks beautiful, he was most struck by how peaceful and beautiful Shiloh was in light of the bloody battle that took place there in 1862. He mentioned that the interpretive waysides installed at Shiloh went a long way in helping him visualize the battle.
This epic walk was the first time Slater visited the United States. He walked at least 20 miles every day, destroying 2 pairs of sneakers, 2 pairs of boots, and whittling 28 pounds off his frame in the process. He met a remarkable assortment of people while he traveled the United States as well, many opening up their homes and cupboards to him.
"The people I met along the way, I'm going to have a bond with for life. This [walk] brought out the optimist in me, and makes me want to help other people realize they are much more amazing than they think," Slater said. "There are more good than bad in this world. I'm honored and lucky to have met every one of the people I encountered."
The only form of transport Slater used were ferries -- one at the very beginning of his trip, and one at the very end, when he took a Statue Cruises boat to Ellis Island. He mentioned that while he was walking around Ellis Island he could not believe that his trek was over. But, on his trip here, he was glad he decided to leave his rucksack elsewhere -- "I've been floating around the city because a weight's been lifted off my shoulders," he noted -- and marveled at the beauty of Central Park.
What did he learn along the way?
"You don't have to be Bear Grylls to do this," Slater said. "I'm an average guy. I took a chance and I went for it. Everyone has great potential in themselves, they just need a believe it to achieve their potential. I don't see problems anymore, I see opportunities."
"Also", he quipped, "The United States looks at LOT smaller on a map."
If you'd like to read more about his trip across the US, check out www.alanwalksamerica.com .


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Steve Proehl is a Bay Area aerial photographer based in Sebastopol, CA. His helicopter work has been published in magazines and book form for the past 35 years. "Over Cape Cod", "Over New York" and "Over New England" published by Houghton Mifflin and Harper Collins all enjoyed multiple printings and became pledge gifts for WGBH, Boston's PBS TV station. His stock photography is represented by Getty.
Steve has been taking aerials in recent years for the solar industry.
Photo Credit: ©Cameron Rolfe


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What is the Best Dental Insurance Plan? One that Offers a Range of Options Suitable for Different Budgets and Needs
The Importance of Dental Insurance
Though many Americans are without health insurance even more are without dental insurance plans - a decision that could lead to major out-of-pocket expenses!
Leading dental organizations and dentists all agree that dental insurance is one of the most important ways of promoting general health and wellbeing. Studies have linked many health related issues to poor oral hygiene including gum disease, heart attacks and even diabetes. Getting routine dental health procedures such as regular checkups and cleanings can be used to spot many dental problems early on and save money. For instance, a simple cavity can turn into a root canal if left untreated, a procedure that could cost upwards of $20,000!
Even routine dental care, however, can cost several hundred dollars a year. Fortunately, information from the National Association of Dentist shows that even at the high-end dental plans typically average less than $40 a month. These cheap dental insurance options are available for individuals and families through private purchase or through employee dental programs. The range of options available means plans can be tailored to best suit an individual's dental needs.
Fee for Service Dental Insurance Plans
One major type of dental insurance plan is the fee-for-service plan, meaning the policyholder pays the dentist directly each time they receive services. These plans can be further divided into two areas:
Dental indemnity plans are more geared towards companies but may also be available for individuals and families. Generally, on an indemnity plan, enrollees can visit any dentist they choose for basic and major care. The individual pays the dentist directly for services then is reimbursed by the insurer after filling out claims forms. A common compliant about such programs, however, is that the claims process is exhaustive and the deductible costs can be high.
Direct reimbursement plans are not technically insurance; instead, they can be classified as self-funded benefit plans. Through direct reimbursement plans, employers cover the cost of insurance out of pocket. Employees choose the dental provider of their choice and pay for their own services. Then they file a claim through their employer and the employer reimburses for all or part of the dental care costs.
Want to learn about the other available dental insurance plans? Continue reading on page 2!
Managed Care Dental Insurance Plans
Managed dental care plans are the other major option to consider. These plans are usually preferred by those seeking a lower cost alternative and typically feature less paperwork. Offerings in managed dental care consist of:
Dental Health Maintenance Organizations (DHMOs) offer access to a network of dentists and specialists at a fixed rate. DHMOs cover most preventative dental treatments at no charge. Non-preventative dental treatments, however, usually require a co-pay. Since the dentist is guaranteed to get paid, less insurance forms are required to be filled out. On the downside, the quality of patient care may be limited and patients are generally required to stick to a primary care dentist for all services.
Dental Preferred Provider Organizations (DPPOs) are plans made up of dentists, specialists and dental hospitals who are paid by service not by patient. DPPOs offer a low premium when visiting dentist in the network but when visiting dentists outside of the network, the individual will have to pay the costs out of pocket. To get the most benefit from the plan, individuals should consider if their preferred dentist is already part of a DPPO network.
Other Alternatives for Dental Insurance Plans
Dental discount plans are also an option for those who cannot afford dental insurance. Even though you are required to pay when receiving services, some plans offer as much as 60% reductions in the cost of certain dental procedures. An annual fee for most dental insurance programs averages less than $200 dollars.
Even though dental insurance has its benefits most plans don't cover the cost of cosmetic dental procedures and even with insurance savings, major dental procedures can still carry high out of pocket expenses. In addition, most plans include a mandatory wait period that limits the coverage in the first year and won't pay for services for pre-existing dental conditions, such as missing teeth.
Proactive individuals can find a number of options to afford the cost of necessary dental procedures. Health care financing programs allow individuals to pay a low monthly rate to pay off the cost of a procedure; however, individuals will have to complete a credit application and may be denied. Most dentists also accept most major credit cards. Cheap dental insurance options can also be found by checking with local dentist schools, contacting local services for low-income individuals and checking with credit unions and professional associations.
The Advantages of Offering a Dental Benefits Plan (https://www.ada.org/369.aspx)
Payment Options (https://www.ada.org/2724.aspx)
National Association of Dental Plans FAQS (https://www.nadp.org/resources/newsletters/faqs.pdf)
Image Sources
Smiling Teeth Don't Come Cheap! (Photo courtesy Photos8.com; https://www.photos8.com)
Teeth X-Ray (Photo courtesy Matthew Maaskant; www.qr5.org)