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Campbell Scientific's IRGASON® fully integrates the open-path analyzer and sonic anemometer. Designed specifically for eddy-covariance carbon and water flux measurements, the patented design is easier to install and use than separate sensors and provides increased measurement accuracy. The IRGASON® simultaneously measures absolute carbon dioxide and water vapor, air temperature, barometric pressure, three-dimensional wind speed, and sonic air temperature. U.S. patent D680455
For more information about the benefits of having a colocated measurement, refer to the poster "Improved eddy flux measurements by open-path gas analyzer and sonic anemometer co-location."Read More
The IRGASON® has the following outputs:
|U.S. Patent No. D680455
|Operating Temperature Range
|-30° to +50°C
|Calibrated Pressure Range
|70 to 106 kPa
|Input Voltage Range
|10 to 16 Vdc
|5 W (steady state and power up) at 25°C
|Measurement Rate
|60 Hz
|Output Bandwidth
|5, 10, 12.5, or 20 Hz (user-programmable)
|Output Options
|SDM, RS-485, USB, analog (CO2 and H2O only)
|Auxiliary Inputs
|Air temperature and pressure
|3 years or 17,500 hours of operation (whichever comes first)
|Cable Length
|3 m (10 ft) from IRGASON® to EC100
Gas Analyzer
|Path Length
15.37 cm (6.05 in.)
A temperature of 20°C and pressure of 101.325 kPa was used to convert mass density to concentration.
Gas Analyzer - CO2 Performance
|A temperature of 20°C and pressure of 101.325 kPa was used to convert mass density to concentration.
|Precision RMS (maximum)
0.2 mg/m3 (0.15 μmol/mol)
Nominal conditions for precision verification test: 25°C, 86 kPa, 400 μmol/mol CO2, 12°C dewpoint, and 20 Hz bandwidth.
|Calibrated Range
|0 to 1,000 μmol/mol (0 to 3,000 μmol/mol available upon request.)
|Zero Drift with Temperature (maximum)
|±0.55 mg/m3/°C (±0.3 μmol/mol/°C)
|Gain Drift with Temperature (maximum)
|±0.1% of reading/°C
|Cross Sensitivity (maximum)
|±1.1 x 10-4 mol CO2/mol H2O
Gas Analyzer - H2O Performance
|A temperature of 20°C and pressure of 101.325 kPa was used to convert mass density to concentration.
|Precision RMS (maximum)
0.004 g/m3 (0.006 mmol/mol)
Nominal conditions for precision verification test: 25°C, 86 kPa, 400 μmol/mol CO2, 12°C dewpoint, and 20 Hz bandwidth.
|Calibrated Range
|0 to 72 mmol/mol (38°C dewpoint)
|Zero Drift with Temperature (maximum)
|±0.037 g/m3/°C (±0.05 mmol/mol/°C)
|Gain Drift with Temperature (maximum)
|±0.3% of reading/°C
|Cross Sensitivity (maximum)
|±0.1 mol H2O/mol CO2
Sonic Anemometer - Accuracy
|The accuracy specification for the sonic anemometer is for wind speeds < 30 m s-1 and wind angles between ±170°.
|Offset Error
|Gain Error
|Measurement Precision RMS
|Speed of Sound
|Determined from 3 acoustic paths (corrected for crosswind effects)
|Innovative signal processing and transducer wicks considerably improve performance of the anemometer during precipitation events.
Basic Barometer (option -BB)
|Total Accuracy
|Measurement Rate
|10 Hz
Enhanced Barometer (option -EB)
|Vaisala PTB110
|Total Accuracy
|±0.15 kPa (-30° to +50°C)
|Measurement Rate
|1 Hz
Ambient Temperature
|BetaTherm 100K6A1IA
|Total Accuracy
|±0.15°C (-30° to +50°C)
|EC100 ingress protection
Please note: The following shows notable compatibility information. It is not a comprehensive list of all compatible products.
EC100 Operating System.
Watch the Video Tutorial: Updating the EC100 Operating System.
EC100-Series Support Software.
A software utility used to download operating systems and set up Campbell Scientific hardware. Also will update PakBus Graph and the Network Planner if they have been installed previously by another Campbell Scientific software package.
Supported Operating Systems:
Windows 11, 10, 8.1, 8, and 7 (Both 32 and 64 bit)
Number of FAQs related to IRGASON: 21
Expand AllCollapse All
The molecular sieve is a non-hazardous material that can be shipped to any country.
The molecular sieve is a direct replacement for the old magnesium perchlorate bottles. The molecular sieve may be used for any Campbell Scientific analyzer that used the old bottles.
The molecular sieve has been demonstrated here by our engineering department to be effective at removing CO2 and H2O from the air sample. The change was made for two reasons:
For greatest accuracy, Campbell Scientific recommends that a zero and a span be done on the EC150 or IRGASON. However, if a span gas is difficult to obtain, at the minimum, perform a zero on the analyzer. Performing a zero will correct the majority of drift experienced by the analyzer. Follow the zero procedure in the analyzer's manual for details.
Yes. A fine-wire thermocouple, such as a FW05, can be used.
The bottles of sieve for drop-in replacement contain the pellets and a membrane on top. The membrane is necessary to keep the pellets contained while allowing gas to pass over the zeolite. The bottle has the same footprint as the old magnesium perchlorate bottles. The amount in each bottle is listed on the bottle. The amount of sieve needed for each analyzer is the following:
The minimum height for the IRGASON or EC150 should be approximately 2 m. Sensor placement below that height may result in a significant loss in frequency response. The maximum height depends on the available upwind fetch or footprint area. As a general guideline for unstable boundary layer conditions, the height of the sensor should be less than the distance from the sensor to the outermost edge of the footprint area divided by one hundred. For example, if there is 500 m of available upwind fetch, the IRGASON or EC150 should not exceed a height of 5 m. Note that for neutral and stable conditions, the footprint area will grow.
Differences between the sonic calculated temperature and the air temperature measured by a more traditional sensor do not necessarily indicate a problem. Sonic anemometers, because of their high sensitivities to sonic geometry and transducer response time, do not typically measure absolute temperature as accurately as traditional temperature probes. Even very small changes in geometry can lead to errors in sonic temperature because sonic temperature is proportional to the square of any error in the distance between sonic transducers. As an example, a change of only 200 micrometers in sonic path length at room temperature yields a 1°C change in measured sonic temperature.
Even though sonic anemometers are generally not recommended for measuring absolute temperature, they excel at measuring fast temperature fluctuations, which are needed for eddy-covariance calculations (sensible heat flux). Furthermore, the error in sonic temperature in most cases can be regarded as an offset after sonic temperature has been corrected for humidity, and therefore, it will not have an effect on the covariance calculation. Nevertheless, if a user desires to calibrate the sonic temperature to account for this offset, this can be done using the temperature reading from a collocated temperature probe, such as the EC150 or IRGASON temperature probe.
The factory calibration accounts for CO2 and H2O signal strengths down to 0.7. Therefore, to ensure quality data, windows should be cleaned before signal strengths drop below 0.7.
The EC150 and IRGASON gas analyzer windows are polished, slanted at an angle, and coated with a hydrophobic material to prevent water from collecting on their surfaces. Wicks may also be used on the windows to promote capillary action and move water away from the window edges. Also, heaters in the snouts may be turned on to help minimize data loss because of precipitation and condensation events.


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Oct 02 2010
just a blog hop
Welcome to Just A Blog Hop!
If you came here from Denise Marzec's blog then you're on the right track. If not, then you'll want to head over to Jami Sibley's blog to start the hop from the beginning. Next stop on the hop is Deborah Robb!
We were invited to put aside all of our stamping oriented obligations and deadlines and create something just for fun. The hop guidelines were simple: choose a challenge to play and choose either a new uninked stamp or an old favorite. Create a card and mail it to someone. What could be better to celebrate World Card making day? I decided to play one of the Splitcoststampers Sketch Challenges from the past few weeks: Sketch Challenge 298!
I love to do sketch challenges because it helps take a big load off when you just want to enjoy using some new (or old!) stamps! A lot of times the sketches help me decide which stamps to use for a project. I knew I wanted to do a Halloween card and loved the fun and simple layering to this layout. I used one of my PaperTrey Ink stamp sets, I just love the charming simplicity of the lines in their images! This spider was yet to be inked, so he was perfect for today!
I do hope you forgive me for the poorly cut out spider! I had high hopes to have my craft room put together so that I could stamp in an organized room, but as it happened I got sick this week and spent some time napping instead of organizing (it was kinda nice to have a good reason for a nap. LOL!). I also have yet to find my box of SU! ink pads, scissors, stamp cleaner, and sewing machine foot peddle, among other lost treasures that I am desperately hoping are in my garage! However, if you saw the scissors I used to cut out those little legs you'd believe in Santa Claus.
As a special treat for Just A Blog Hop, I'm offering a "Treats Only" give away! Just leave a comment and on Monday I'll announce the winner! You'll receive this card along with a box of stamping goodies, including at least one stamp set! This is coming from my stash that I just don't use and it's making me sad to see it neglected.
I hope you enjoy Just A Blog Hop and find some inspiration to celebrate World Card Making Day!
Your next stop is Deborah Robb! 😀
21 responses so far
21 Responses to "just a blog hop"
Super cute, Emily! Love the beautiful fall colors in that patterned paper!
I love the sweet simplicity of your card, and I think you did an awesome job cutting out that spider! Well done!
So nice card! Love the spider and papers you used. Thanks for sharing. Happy World Card Making Day 🙂
That spider is so cute! Great card!
That is so cute! I love how you curved the "ribbon" tag! Very cool. And thanks for the chance to win something! Hurray! 😀 Happy WCMD to you!
What spooky fun!! Love your little boo flag with that spider!!
Spooky card! Love the cute cut out spider. Great papers and tag! Enjoy the rest of WCMD. :o)
So good to see you stamping, Emily! I would have never attempted cutting out that spider. You ROCKED him! Loved catching up a little in your life. Congrats on the new house, and I adore your crocheted hats! Super sweet! Happy WCMD!
You KNOW I love it when you stamp girl! So cute! And the scissors thing cracked me up! I can just picture you using a huge pair of shears or maybe a dull pair of kid scissors!
That card is too cute and the spider was cut better than I could ever!
Oh I love how you did the curvy tag! Fun!
Cute Halloween card! I always check out your blog, thanks for sharing your talents!
Great card, Emily. I don't usually do Halloween Cards, but yours sure is inpiration to start! You are a saint to cut all those legs – please show us the scissors you used?!?!?!
Wow! I wish I had your patience! Cutting that spider out sure makes this card POP! Love that you took the time to do that! Awesome!
You always amaze me how you can see potential in some pieces of paper from your paper scraps (I would have gone with the oblivious piece of Halloween paper that had little ghost or witches or skeletons, but used a poked-dotted and plaid scraps with fall colors) and the colors combination (Again, I would have stayed in the oranges and blacks, but combined to me what is an ugly stone-like color to pop the spider) you use with a simple spider (cute spider with glowing eyes) and halloween word "boo" to make a clearly understood darling Halloween card.
You can give the prizes to someone else, just send me the card!!
P.S. Plus, I know what your craftroom looks like and that you dared to do something un-yarn type is amazing—LOL (such a mom thing to say)
What a fun card! I think your cutting out of the spider rocks… if I had attempted those little legs my spider would be an amputee (probably multiple limbs at that). 🙂 Hope you find your missing stamping goodies soon!
Cute card! I can't believe you cut out that spider with such precision… wow! I also like the 3D paper ribbon/banner… at least that's what I think it is… please correct me if I'm wrong. I would love to win your card!!!
WOW! Fabulous card! Love, love, love the BOO ribbon tag! Outstanding job on the sketch!
Adorable card.
Your card is super cute! Hope you find your missing items! Yikes, they are kind of important! btw, I think your spider looks perfect!!
I just came across your blog and am now following you. Love this cute spider card and am looking forward to seeing other things you do. Have a blessed day.

subset: commoncrawl


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Eli Manning downplays the age factor as Giants open camp
EAST RUTHERFORD, N.J. (AP) Don't bother talking to Eli Manning about his age.
Entering his 14th season, the 36-year-old New York Giants quarterback just smiled Friday when asked about the number and comments by general manager Jerry Reese that the two-time Super Bowl MVP will be on somewhat of a pitch count in training camp.
The goal seemingly is to limit the wear and tear on the ''old guy's'' arm heading into a season when the Giants have high hopes following their first playoff berth since winning the Lombardi Trophy in February 2012.
''I know how old I am,'' Manning said after the Giants held their first training camp workout. ''I don't think there's anything wrong with being 36. I'm proud of it. Hey, I feel good. I can still make all the throws. I can still run around when I need to. So, it is what it is. But I don't see myself slowing down at all and I feel like I still got great football ahead of me.''
Giants co-owner John Mara agrees.
''He shows no signs to me of slowing down,'' Mara said. ''He is highly motivated to win another championship. To me, he looks as good as he ever had, so we are excited about him.''
The Giants' offense did not have a good season in 2016 despite making the playoffs. The unit was ranked 25th overall, with the run game at No. 29 and the passing game at No. 17.
Manning hit 377 of 598 passes for 4,027 yards, 26 touchdowns and 16 interceptions. His quarterback rating of 86.0 percent was in the lower third of the league.
One of the major problems was the offensive line. There was no running game and Manning was knocked down more than the Giants wanted, getting sacked 21 times and punished by hits much more than that.
''Eli has to take care of himself and get himself ready to play mentally and physically,'' Reese said Thursday. ''When guys get up in age, you have to take care of them. There are a few guys on the squad that coach McAdoo and our staff, we've talked about, `OK, let's make sure these guys get to the game, get to the season.' You've got to protect them in some ways.''
Manning downplayed the so-called pitch count. He said he has been on one since Ben McAdoo took over as offensive coordinator in 2014 and then became the head coach last season.
It's not so much a pitch count. Manning throws more on some days and less on others. On the days he throws less, he works more with the starters.
Manning is excited about the changes the team has made in the offseason. Former Jets wideout Brandon Marshall was signed as a free agent and New York drafted quick tight end Evan Engram in the first round.
The additions should make it tougher for opponents to double playmaking receiver Odell Beckham Jr., while creating mismatches for Manning to exploit if he gets the time to throw.
''I'm excited about the year, just knowing the guys and the character that we have on this team,'' Manning said. ''Guys have worked hard in the spring; we got better and added some elements, and so I'm excited about raising our level of play and being explosive on offense and scoring points and having a strong defense. So, the possibilities are there. We just got to get to work and we got to make it happen.''
NOTES: LB J.T. Thomas was placed on the physically unable to perform list. McAdoo hopes to have him back shortly. ... DT Damon Harrison is a little sore and will be brought along slowly in training camp, McAdoo said. ... The first practice last roughly 80 minutes, relatively short for early in training camp. ... Former Jets QB Geno Smith (knee) has been cleared to practice. ... Beckham is in great shape. ''Looks like he can roll out of bed and run a 4.3,'' McAdoo said.
For more NFL coverage: http://www.pro32.ap.org and http://www.twitter.com/AP-NFL


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Learn Italian with LearnItalianPod. Italians love food, and love to eat… that's a fact. For them, food is pleasure as much as nourishment. What they also love to do is to express opinions about people or things using food names that best describe them! So, let's follow Lucia and Italo as they play this little funny game called "Say It with Food": the first that cannot come up with a popular idiomatic sentence that uses food names to express opinions about people or things loses. Get ready to learn and practice some of the most common popular Italian idiomatic expressions you'll ever hear, a lot of food names, and have lots of fun!
[LearnItalianPod VIP Members Extra Bonus!] Login to the Learning Center to download Audio & PDF Transcript of the "must-know" Italian verb "Mangiare" (To Eat).
Upper Intermediate – Episode Nr.19


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Online help for matrics to get into varsity
The Central Applications Clearing House (CACH) online application service for matriculants, who struggled to secure a place at the educational institution of their choice, will open from 5 January - 28 February 2018.
CACH services are particularly useful for applicants who applied for admission to a university or college in time, but have not been offered a place or their programme of choice.
It can also be useful for prospective students who achieved better than expected results, and now wish to access a different course or university or Technical and Vocational Education and Training (TVET) college.
Students who missed the application window period for one reason or the other can also use CACH services.
CACH was established in 2013 in response to the large number of applicants seeking entry to the Post School Education and Training (PSET) sector in January, when most universities have closed their application process.
It is provided by the Department of Higher Education and Training as a service that is free to both applicants and institutions.
Now in its fifth year, CACH has attracted 18 329 applicants.
A survey taken on 10 087 applicants in March 2016 revealed that 33% (3 328) of students had found a place in PSET or employment since contacting CACH. A survey taken of 11 770 applicants in March 2017 revealed that 37.3% (4 390) of students had found a place in PSET, or employment since contacting CACH.
This reflects an increase of 1 062 learners finding a place in the PSET sector. The increase is an indication of the positive impact of CACH.
Registration can be done on CACH's website: http://cach.dhet.gov.za. Alternatively, prospective students can call the toll-free call centre number on 0860 35 66 35 from 8am to 8pm.
CACH is also contactable via standard SMS (name and ID) to 49200 or by email: email@example.com.
Central Application Service
Meanwhile, the Department of Higher Education and Training (DHET) has recently approved a policy for the establishment of a Central Application Service (CAS) for PSET.
The policy is an initial step in the legislative process to establish a one-stop online application system for students to access multiple institutions without the need to queue at those institutions.
CAS is aimed at streamlining and simplifying the application and admissions process. The new system will allow applicants to use the system for a range of tasks such as investigating opportunities, preparing, submitting and changing applications, and considering and accepting offers.
The CAS system will prepare application cycles, capture off-line applications, check and submit applications, communicate with applicants, resolve queries and refer rejected applicants to other opportunities.
PSET institutions will prepare programme data, receive applications, select and make offers, and register and admit students.
The main users of the system will be all entering undergraduates, who can apply for academic programmes, as specified by individual institutions.
It is envisaged that the CAS will become fully operational in 2024 for 2025 applications. – SAnews.gov.za


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To order images and/or obtain permission to use them commercially, please contact the KSHS Reference Desk at firstname.lastname@example.com or 785-272-8681, ext. 117.
For more information see the Copyright and Permission FAQ.
A photograph showing the remains of the First National Bank after a fire in McPherson, Kansas.
Date: Between 1910 and 1915
Item Number: 225460
Call Number: FK2.M3 M.4 Fi. *1
KSHS Identifier: DaRT ID: 225460
Business and Industry - Banking - Banks
Collections - Photograph
Community Life - Disasters and accidents - Fires
Date - 1910s
Objects and Artifacts - Communication Artifacts - Documentary Artifact - Photograph
Places - Cities and towns - McPherson
Places - Counties - McPherson
Type of Material - Photographs


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Members of San Francisco State's Student Section of the American Society of Mechanical Engineers (ASME) are working with Whirlwind on building a hand-powered front-wheel-drive tricycle as a club project. The club has been responsible for welding, fabricating, and contributing to the iterative design process through testing. "The team of undergraduate students is learning valuable skills…Read More
FastCoExist, a project of FastCompany Magazine, covers Whirlwind's offering to US wheelchair riders who'll access trails, gardens, and beaches like never before.Read More
"Charity Gives People In Haiti These Awesome All-Terrain Wheelchairs" Bill Clinton and other fabulous guests attended the premier of The Way by Emilio Estevez with Martin Sheen. This eventwas also a benefit for The Walkabout Foundation. Read The Story Here.Read More
Ralf Hotchkiss teaches a wheelchair design and fabrication class at San Francisco State University and enlists the help of students in continually improving wheelchair designs for the developing world. Read The Story Here.Read More
Ralf Hotchkiss experiences the travails of a wheelchair rider on San Francisco public transit. Read The Story Here.Read More
Transcription for this video: Haiti Project with The Walkabout Foundation After the devastating Haiti earthquake of 2010, many Haitians suffered severe injuries, while much of much of the country's infrastructure laid destroyed. Whirlwind recognized that there was a urgent need for the RoughRider wheelchair, which is specifically designed for rough terrain. We offer our special…Read More
An introduction to Whirlwind Wheelchair International and our newest chair, the RoughRider, an all-terrain wheelchair built by and for riders in the developing world. Whirlwind is a non-profit wheelchair company that specializes in creating durable low cost wheelchair technology that gives riders the opportunity to explore more places and do more things.Read More
Transcription for this video: Wheels of Change by PBS Frontline_World Frontline covers Whirlwind Wheelchair's poverty relief efforts in Vietnam and local partner who manufactures the RoughRider wheelchair. This video also covers the inspirational stories of Tong Geong and his friend Quan Dien; both are wheelchair riders who live in the busy city. Whirlwind is a…Read More
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To register for the next
Wilderness Advanced First Aid
Clinic click here
|We had a very successful Clinic in June 2012. The feedback from the class was outstanding. The next classes is scheduled for June 2013.
The WAFA course was a tremendous learning experience that opened my eyes to new ways of holistic and critical thinking necessary to assess problems,
weigh risks/benefits of various actions, and develop plans for backcountry emergency situations.
A great balance of theory, practical information, and invaluable simulations and feedback left me feeling more confident and prepared in wilderness settings.
The instruction was engaging, informative, fun, and effective these were quickest 4 days of my life.
I would recommend this course to anyone who spends time in the outdoors.
Eric Constantin
The Wilderness Advanced First Aid clinic will provide you with skills, knowledge and training to handle life threatening medical emergencies and allows you to be better prepared to protect your family in an emergency.
Course materials include a book of lecture handouts, SOAP Notes, The Outward Bound First-Aid Handbook by Jeffrey Isaac, and The Wilderness Medical Associates Field Guide.
Syllabus:Day 1: 9 hours - Introduction/Registration; General Concepts; Infection Control; Patient Assessment System; Circulatory & Respiratory Systems; Adult CPR; Basic Life Support
Day 2: 9.5 hours - Quiz/Case Studies; Nervous System, Spine Management; Musculoskeletal Injuries; Lifts, Moves, and Extrications; Splints - Extremities; Patient Assessment Drills
Day 3: 9.5 hours - Quiz/Case Studies; Thermoregulation; Bites and Stings; Lightning; Elective Topics; Wounds and Burns; Allergies and Anaphylaxis; Improvised Patient Carries; Patient Assessment Drills
Day 4: 8 hours - Case Study Review; Elective Topic; Backcountry Medicine; Medical and Legal Issues; Patient Assessment Drills; Simulations; Final Exam; Conclusion
Location:The class is held at the Hungry Valley State Vehicle Recreation Area (HVSVRA) near Gorman, CA. Hungry Valley SVRA is located in the Tejon Pass about 50 miles north of Los Angeles, CA just west of the Interstate 5 corridor. Hungry Valley has 9 camp grounds each with a multitude of sites. For more information check out their web site Hungry Valley State Vehicular Recreation Area.
Lodging:Lodging is not included in the tuition cost, and you need to make your own arrangements for a motel, a camp site or some cases commuting. There are several motels nearby: a Travel Lodge in Gorman and a Motel 6 and a Holiday Inn Express in Lebec, CA. Lebec is about 2 miles north of Gorman on I-5. You can also use the public camp grounds in Hungry Valley SVRA.
Sponsor:Badlands Off-Road Adventures is the sponsor of this class. We engage professional medical instructors from Wilderness Medical Associates, the certifying agency.
|| Phone 310-613-5473


text:
ALBANY, NY — New York State Department of Transportation Acting Commissioner Paul A. Karas today announced that work is getting underway on a project to replace a culvert carrying State Route 193 over Bear Creek in southern Jefferson County. The culvert carrying State Route 193 over Bear Creek was damaged by flooding in September 2017 and Route 193 was subsequently closed as a precautionary measure.
"There are literally thousands of elements that are vitally important to the functionality of New York's vast transportation network," Acting Commissioner Karas said. "This culvert is critical to the local highway system and to those who have come to depend in it."
Soon after the road closing last fall, the culvert was damaged beyond repair by high water. A contractor was mobilized to remove the culvert and stabilize the site as an interim measure while a replacement bridge was designed. By accelerating the design and award process, the replacement bridge will be reopened in the summer of 2018.
The completion of the project on an accelerated timeline will enable local farmers to access their crops easier and will allow local traffic to return to a normal pattern more quickly.
Senator Patty Ritchie said, "Reliable infrastructure is key not only to the safety of motorists, but also to the strength of local economies. I am pleased that repairs are being made to State Route 193 that will help to reopen this stretch of roadway and make travel more efficient, as well as safer."
Assemblyman Will Barclay said, "The DOT made the right decision to close State Route 193 over Bear Creek before a tragedy occurred. I am pleased the DOT is making the replacement of the culvert and its infrastructure a priority so the road can be reopened. The DOT recognizes how the loss of access has been difficult for many residents and businesses in Southern Jefferson County and the Town of Ellisburg. I am glad to hear that the project is moving forward."
Traffic at the project location will remain on the existing detour, which uses State Routes 178 and 289. The $1 million project was awarded to New Century Construction, Watervliet, New York.
Motorists are reminded that fines are doubled for speeding in a work zone. In accordance with the Work Zone Safety Act of 2005, convictions of two or more speeding violations in a work zone could result in the suspension of an individual's driver's license.


text:
The great Czech distance runner, Emil Zatopek, a triple Olympic gold medalist in 1952, once quipped, "It's at the borders of pain and suffering that the men are separated from the boys."
Tracy Lokken is the living embodiment of Zatopek's tough-running caricature. At the age of 46, when many marathoners are spending their time waxing about the glory of days past, when most of them have given up on their youthful PRs and have settled for age-group prizes, Lokken is out breaking American records. Earlier this month at the Medtronic Twin Cities Marathon, which happened to fall on a blustery day with sub-optimal conditions, the Marquette, Mich., native clocked a 2:24:44. (Mbarak Hussein set the American record for the 45-49 age group with a 2:16:57 at the 2010 Twin Cities Marathon.)
So what was the secret to Lokken's success that day?
Humble by nature, Lokken has a typically Midwestern air about him. As an interviewer, this means it takes some time to get to the bottom of things.
More From Runner's World
"I really didn't go into that race expecting anything other than doing the best I could," Lokken says. (Truth be told, he entered the race five days after tweaking his right hip. Fortunately, he found a kinesio tape booth at the expo and got a tape job.)
When pressed further about the race, Lokken shrugs his shoulders and says he didn't even know what place he was in until he finished. "I wasn't really tired," he says. "I just kept plugging away, and before I knew it, at mile 16, 17, 18, I started seeing people and catching them."
Understanding Lokken's background helps put some perspective to his responses. Up until two years ago, the 2010 masters cross country champion was a roofer. If you've ever had a roof replaced, you probably know what it means to be a roofer.
It's not easy, but neither are marathons.
A roofing job requires methodical work. It takes diligence, patience, and especially an almost superhuman ability to tolerate pain in order to carry it out. In the winter, roofs are freezing; in the summer, they sizzle. In a sense, roofing marathoners like Lokken are those best accustomed to living at Zatopek's borders of pain and suffering — that place where the men become boys.
The limits of human suffering aside, Lokken has something else in his corner: dedication. When he was roofing and marathoning, he says he made the time to run. "If I had to show up to work at 6 in the morning, I would get up at 4 to get my running in," he says. "There's no excuse if you aren't putting in the time and effort." After a day of backbreaking work, climbing up and down ladders — work he refers to as "strength-training on the job" — if Lokken needed to get in miles, he'd do it. "I had this nice tan, but at the end of the day, if I had miles left to run, I'd get them in," he recalls.
Lokken no longer installs roofs; he's now a wellness center facilitator for the YMCA and says that switching from a physically demanding job to one that allows him the time to "stay consistent" with his training is what has helped him further succeed in the masters realm. "I'm fortunate enough to be afforded the time off to train," he admits.
Successful in high school and in college at Northern Michigan University, Lokken eventually lapsed as a runner for eight years — from when he was 27 to 35. "When I finally put my shoes back on, I said, 'You know what: I just want to stay consistent with everyday training.' I would put six, even all seven days in. I just said that I'm not going to miss days."
Lokken stayed true to his word. When he was 39, he ran a 2:23 marathon in Detroit off his "consistent training" concept. His marathon PR, however, didn't come until five years later. At the age of 44, Lokken clocked a 2:22:34 at the Twin Cities Marathon, winning the U.S. masters championships that year.
So, again, what's the secret to his success? How, at the age of 46, is Lokken managing to run as fast as someone decades younger than he is. After getting past Lokken's "consistent training" response, it turns out he's doing other things — things like consistently racing and logging triple-digit mileage.
Racing-wise, Lokken competed in this year's Boston Marathon. Beneficial tailwinds aside, he ran 2:26:00 — good enough to win the men's 45–49 division and the first American masters runner to cross the finish line. In a race with nearly 27,000 participants, he placed 47th overall. Two months later, Lokken was in Duluth, Minn., at the Grandma's Half Marathon where he ran a 1:09:16. "I just picked and chose my spots as far as racing goes," he says. "Between Boston and Twin Cities, I think I got about five or six races in."
Mile-wise, when not racing, Lokken was doing week after week in the 100s. But he's also also a proponent of tempo runs. "I like them," he says. "You know, doing those pickups for 20 to 30 minutes of hard running. I do some strides too — to keep the legs sharp."
For the fall, Lokken is setting his sights on the shorter-distance events. After being sidelined due to meniscus problems last year, he was unable to defend his masters title at the U.S. club cross country championships. He hopes to return to this year's championships on Dec. 10 in Seattle.
"After Twin Cities, I've been enjoying this unseasonably warm weather," Lokken says. "It's deer season here in Michigan, too, but once the temperatures get normal again, I'll be getting back into it."


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The season is still only three games old but UNLV appears to have already mastered a very important trait … free throw shooting.
The Runnin' Rebels, who were 13-of-13 from the line in the second half of Wednesday night's 74-62 victory over UC Riverside, once again were nails in crunch time during a 77-68 win over Cal State Fullerton on Saturday night at the Thomas & Mack Center.
UNLV (2-1) shot 81.3 percent from the line (26-of-32) and made its last nine in a row over the final 2:57 to hold off the Titans (2-2).
Guard Jovan Mooring, one of five Rebels to finish in double figures, made 10 of his 11 free throw tries while scoring 12 straight points over a key four-minute stretch that saw UNLV build its lead to nine points, 63-54.
Cal State Fullerton got as close as four points, 71-67, on a 3-pointer by freshman Davon Clare with 35 seconds left, but Rebel point guard Jalen Poyser (4-of-4) and forward Dwayne Morgan (2-of-2) were perfect at the line to close out the win.
It was the 200th coaching victory for first-year UNLV head coach Marvin Menzies in just his 10th season as a Division I head coach. Menzies is now 200-112 in his coaching career.
HOW IT HAPPENED: With the game tied, 46-46, senior forward Uce Ofoegbu hit a desperation beat-the-shot-clock 3-pointer – one of three for the Rebels in the game – to put UNLV ahead to stay. The Rebels managed just four more field goals over the final nine minutes but thrived at the free throw line sinking 19 of their final 21 attempts.
WHO STOOD OUT: Poyser led the Rebels with 14 points, including a pair of buzzer-beating 3-pointers, and also had three assists and just one turnover. He also did a solid job defensively part of the game on Cal State Fullerton guard Tre' Coggins who finished with 17 points on just 6-of-18 shooting. Morgan, in just his second game back from a hip injury, finished with seven points, eight rebounds and two steals in 21 minutes of action.
All the highlights you need from the 77-68 win over @FullertonHoops at the @ThomasAndMack! #UNLVmbb pic.twitter.com/abu0Id70Kt
— UNLV Basketball (@TheRunninRebels) November 20, 2016
QUOTES TO NOTE:"Before every game we have two separate groups that compete against each other at the free throw line and no one wants to lose so you better make your free throws. (The losers) have to run like crazy. … Definitely (think it carries over into games.)" – UNLV guard Jovan Mooring.
"It's just not me. It's your staff, it's your players, your whole family. I get the credit if for it." – Menzies on his picking up his 200th coaching win.
UP NEXT:The Runnin' Rebels return to action Tuesday night when they host Northern Arizona at 7 p.m. at the Thomas & Mack Center.
NOTABLE: UNLV is shooting 79.5 percent at the free throw line this season which ranks 19th in the nation. The Runnin' Rebels have outscored their first three opponents by an average of 22 to 12 at the free throw line. … Senior guard Lionheart Leslie, listed at 5-foot-10 on the roster sheet, scored a game-high 21 points and grabbed a game-high 10 rebounds for Cal State Fullerton. … The Rebels forced 17 turnovers and finished with a 14-6 edge in points off turnovers. … Cal State Fullerton outrebounded UNLV, 40-27, as the Rebels managed just two offensive rebounds and two second chance points. … The Titans, who once again hurt the Rebels with drives to the basket, finished with just seven assists on 23 made field goals.
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McEnroe proves he can be serious about Edinburgh
THE ATP "Champions of Tennis" tournament will bring the legendary John McEnroe back to Scotland for the first time in over two decades in June.
Law firm Brodies is taking the title sponsorship of the Edinburgh event which promises to give the greatest players in the history of the sport a chance to play "nostalgic, competitive and entertaining" tournaments in cities around the world.
But the question remains: will it give Grant Campbell, international strategy partner at Brodies, a chance to play one of his heroes? Sources suggest Campbell is "a keen tennis player – 1984 Carnoustie boys singles champion!" Meanwhile, fellow law firm Blackadders hosted Legus, an international network of corporate and commercial lawyers, at the Old Course Hotel in St Andrews last week.
Attendees came from as far afield as Mexico, Nigeria and the Philippines. Blackadders said festivities included an "out of season" Burns Supper at Mains Castle in Dundee. They didn't mention if anyone had a chance to play some golf.
Grossart's animal magic
Sir Angus Grossart used the latest Noble Grossart accounts to bring a menagerie of cryptic animal metaphors to the sometimes fishy world of merchant banking.
His chairman's statement took a swipe at the wild world of highly leveraged balance sheets that led to the financial crisis.
Referring to the practice of "marking to market" that allowed unrealised profits to find their way into accounts, he said: "It did not take long before opportunistic cats began to enter that particular fish shop."
Grossart also pointed out that voices of experience from previous downturns were "unheard until the wolf did arrive at the door". For the financial crisis itself he aptly alluded to the man-made disaster of the Titanic – but was careful to point out his own operation had navigated by different beacons.
Chivas bags Barbados deal
Bagpipe maker Hamish Moore and PR guru Carol Anderson are toasting the success of their Celtic Festival Barbados after Chivas Brothers, Scotland's second-largest whisky distiller, and Mount Gay rum were signed up again as sponsors.
The festival – which takes place on the Caribbean island on 23-29 May – celebrates Barbados' connections with Ireland, Scotland and Wales.
Taking the stage at this year's festival is Seudan, a quartet of pipers playing in the old pre-military step dance style.
Edinburgh-based chef Paul Wedgwood is also returning to the island for a third year to add Caribbean ingredients to his traditional Scottish fayre.
And who can blame them? Our sources tell us that Barbados has as many rum shops – 1,600 of them – as it does churches. Now where do we book those flights...?


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First, and foremost, laptops are meant, by design, to be portable. Their counterparts, desktops are the ones you don't throw in your briefcase or backpack and take around with you. Therefore if you're buying a laptop, instead of a desktop, one of your obvious goals is for it to be, at least a little bit, portable. Now that we've established that, there are obviously different degrees of portability, and if you're considering buying a laptop, this is probably where you should begin. Let's address the spectrum so you can place yourself somewhere on it. On one side (the light side) you have business laptops, which can weigh as little as 1-2 pounds, and is for, as the name states, people in business and/or people who travel a good amount. On the other side you have "desktop replacements," which are mostly used by gamers, entertainment enthusiast, and maybe people in the graphic/video industry; these can weigh over 10 pounds. Then, there's everything in between, which is approximately 4-7 pounds, and is what most people tend to purchase. If you're a student, or someone who must traverse large distances with no car (seriously you wouldn't believe how big some college campuses are), definitely shoot for lighter. Try to place yourself somewhere in the 3 categories first, then work from there; there's definitely a lot of leeway here though – I know graphic designers with 11 inch laptops (who consequently use an external monitor), and students who only word process with a 17 inch laptop.
Next, let's discuss the relationship between screen size and weight. The most obvious thing to start out with is, the bigger the screen size, the heavier the laptop. I know 17 inch laptops seem appealing, but unless you're a die-hard gamer or watch tons of videos on your laptop (video and photo editors included), I'd stick to a 15 inch. 13 inches and under, in my opinion, is a tad small. It's difficult to be ultra productive on a 13 inch screen, because you can't have several windows open side by side. You could always get a 13 inch loaded with a high definition amount of pixels, but it's never nice to have things so small that the text is straining to read. If you only really plan to word process, use the internet, write emails, and watch the occasional video, then the 13 inch might be an option. Quite simply, try and go as light as you can, without compromising screen space.
Alright, now one of the bigger aspects for many people: the relationship between size and cost. In most cases, bigger means better and better usually means more expensive. But, go on a laptop site and you may end up seeing the opposite, gaming computers an exception. I know earlier I said shoot for lighter, and now it seems as though I'm contradicting myself, but the key here is to find a balance between lightness, functionality, and price. When laptops get smaller, especially in the business aspect, they tend to get more expensive. As it turns out, it is rather expensive to cram high performance parts into small spaces, go figure. So if you're on a limited budget, and want to maintain decent functionality, stay away from the 13" laptops. Now, let's address the issue of big laptops. Once you go from 15 inches to 17 inches, the chassis and the screen get more expensive, and thus your price goes up – pretty simple. 17 inches is the choice for most gamers and photo/video editors, because more performance parts (like SLI enabled graphics cards) and bigger screens with more pixels. These are also reasons why you may want to consider it if you're a serious videophile. If you're looking for an ultimately cheap alternative there are miniature laptops that can basically word process and surf the internet for very cheap (a couple hundred).
Finally, if you're still confused, well let me just try to tell you what I think you should do. If you've read the previous paragraphs, you can see that on average, and based on the functionality, weight, and price ratios, 14-15 inch laptops are probably the size to gravitate toward. This is especially true if you're moving your laptop over extended distances (more than from the car to the home office, and from the car to the actual office). Serious gamers and people that love entertainment, and don't plan to move extended amounts, go toward the 17 inch side. Frequent travelers and businessmen look to the 13 inch laptops. If you're going through the airport, and/or if you have to carry something in your briefcase (as opposed to backpack or pseudo-backpack), you definitely want ultra-light. For everyone else, my recommendation, as I've said several times before, go for the 15 inch. Hope this helps answer some questions, but if you want some more perspective, I'll do a follow up article soon about my experience with my 17 inch laptop.


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Starting today Sky will be rolling its latest redesign to the Sky Go mobile TV service. The new design is available right now on the browser-based version and will soon begin to propagate through Google's servers and onto Android devices.
There will also be an iOS version of the new design coming to Apple users later on in February.
This new, more visual, homepage and design layout is just the beginning. Sky is also promising to introduce new features to the Sky Go service later in the year "to make the experience of watching whenever and wherever even better."
The only one of these it has announced is a 'watch next episode' feature and something to make it easier to find movies similar to those you have been watching.
Sky looks to be really embracing the Netflix and binge culture.
It hasn't made any other concrete announcements as to what these new features are likely to be, but claim they will make the app more intuitive to use and promote more shows, sports and movies to the Sky Go users.
Right now then we are just talking about cosmetic changes to the Sky Go platform.
With its new Sky Q service rolling out early this year it's not unreasonable to assume some of the new features might be tied into the exciting new premium Sky experience, potentially offering a more consistent flow across the platforms.
But what we'd really love is for Sky to introduce full HD streams to its huge on-demand catalogue, but we're not holding our breath for that...


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Vanquish ME Body Contouring
Vanquish ME is the game changer in non-surgical fat reduction and contouring. It doesn't even touch your skin. Contour Medical was chosen as one of only 10 clinics in the entire country to launch the Vanquish ME. Fat is destroyed and you are comfortable with no downtime. Initial studies show an average of 59% of abdominal fat treated was destroyed. The Vanquish ME, at Contour Medical in Gilbert, Arizona, is the most cutting-edge alternative to liposuction available and compliments the other body contouring treatments offered. Vanquish ME the fat!
Vanquish ME Benefits
- No downtime — life as usual after your treatment
- No discomfort — during (slight warmth) or after treatment
- Treat a large area at the same time — abdomen & love handles
- Permanent fat reduction — fat is destroyed yet totally non-invasive
How Vanquish ME Works
This is an "intelligent" device that senses your body fat and adjusts to maximize energy delivery and absorption. The engineering and technology used in the Vanquish ME at Contour Medical, in Gilbert, Arizona, is a huge step forward in non-surgical body contouring; it truly individualizes the treatment for the patient's fat and body type. The fat is super heated and destroyed (melted) while the surface skin temperature is comfortably warm. All of this is achieved without the device even touching the skin — you lay below adjustable panels that sit above the skin. Results are permanent and patients are comfortable in the process.
What to Expect
The sensation of the treatment is a warm feeling, similar to a heating pad and is very comfortable. You can treat the full abdomen, including the love handles, at the same time. If a good candidate, it can also be used to treat the legs, thighs, bra fat, and buttocks. The protocol is four treatments, one week apart. There may be slight redness and minimal swelling after the treatment, but there is no discomfort. Adequate hydration is recommended to maximize results. A complimentary consultation on the Vanquish ME at Contour Medical in Gilbert, Arizona, will help individualize your body contouring treatment plan with the Vanquish ME.


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From Bitcoin to Ethereum: How Blockchain Technology Enables New Brand Tactics
By now, you've certainly read something about how the cryptocurrency Bitcoin is disruptive for financial markets, or how piracy has wrought havoc on the music and entertainment industries. This article isn't going to be long prose about how the sky is falling, but it will talk about a technology that will redefine the way society functions and bring about the next big industrial revolution. If you indulge me for just a few minutes, you'll walk away with actionable thoughts on how you can be on the right side of disruption for your brand.
As marketers and entrepreneurs, we are constantly searching for the next big way to drive value from our investments. By now, you likely have one or more initiatives going on to support Digital Transformation within your organization. You are likely expanding your digital assets, whether it be mobile-first web experiences driving traffic and leads to your CRM, a direct-to-consumer engagement for customer retention, or a VR installation designed to put your consumer inside your vision all run on the power of the internet. But the more popular or innovative those assets are, the more they cost to operate and drive traffic to. Servers and the IT staff that maintains them, security auditors, scaling solutions, monitoring along with all of the Software and Platforms (SaaS and PaaS) that encompass the former have a cost that typically increases with your needs. All of those costs stem from one thing: centralization.
Centralization has given us more control over the experience we provide, as well as the valuable data that our businesses run on. If everyone drinks from the same well, they all benefit from our efforts to keep the water clean. Conversely, it makes it very easy for someone to slip by and poison the well. Think of the rising number of security breaches each year that cost brands millions. Wells can also dry up too, like when websites go down from too much traffic. Bad experiences like this mean more than expensive fixes, they erode the most important things consumers look for today in a brand: trust and customer experience. You can spend a decade building your brand and one violation of public trust can result in them never coming back to you for a burrito ever again.
The solution to all these issues is to decentralize. One decentralized technology in particular has arisen from the minds of dreamers and makers that is poised to solve a massive swathe of the problems we face with our digital assets today. Used for the right things, it eliminates entire classes of complications and vulnerabilities, as well as the upfront infrastructure investment. Big minds and deep pockets like IBM, Intel and Microsoft, as well as the World Economic Forum expect this technology to hail a fourth industrial revolution. Whole new ways of doing business are expected to arise, and maybe even the way our society is structured will change as a result. The technology is called blockchain, and here's how it works.
"Blockchains are at the heart of the fourth industrial revolution."– Klaus Schwab, Founder and Executive Chairman for the World Economic Forum
What is a Blockchain?
If you have ever utilized a file sharing protocol such as BitTorrent to download music or for any of the more legitimate uses (Windows 10 uses something similar to distribute updates for example) then you've already experienced the distributed aspect of the blockchain. And if you've ever ran the finances of a company you're familiar with another aspect, a ledger. A blockchain is fundamentally a record of transactions and ownership (ledger), distributed for public audit, verification and storage by each participant. It has the peculiar property for a digital record of being unable to be modified. Once a transaction is recorded, it stays for good and can only be built upon by a new transaction. Like a cuneiform tablet from the ancient Sumerians, everything is set in stone.
On top of this, every new transaction is verified by a quorum before being added. It's as if you were to pause in the middle of a deal and have everyone in the world look over it to weigh in on the validity of the transaction. Computers, of course, are much better at doing this than we are.
Getting to Clarity on a Complex Topic
"That sounds sexy and all," you say, "but how exactly does that drive better value for my investment?" The answer is simple to grasp: Blockchains enable permanence and uniqueness of digital assets. In a world that is used to everything that exists in code or data being readily duplicable and alterable, that is huge. What once required tight control of a unique ecosystem to preserve is now readily available, and your users provide the computation, storage and the strong security to make it happen.
"Blockchains enable permanence and uniqueness of digital assets." – Dan Poulin, Technology Lead at Digital Surgeons
The Beginning: Bitcoin and the New Breed of Blockchain
The most widely known example of a blockchain is the Bitcoin network. Bitcoin has proven that the method works; that we can have digital assets with real worth and a high degree of reliability and safety. But a cryptocurrency is perhaps the most straightforward use of a blockchain, and it is now the most uninteresting. Bitcoin solved the first issue, the issue of permanence and uniqueness of digital assets, but new blockchains such as Ethereum, Chain, IBM's Fabric, and Intel's Sawtooth Lake add another layer of sophistication by introducing the concept of a Smart Contract.
A smart contract is a piece of code which determines the rules of how a transaction will take place. This is an important advancement, because it means we can move beyond simple transfers from party A to party B. Smart contracts enable the blockchain itself to store who can own what digital asset, on what terms, and what those assets are. With the combination of value and rules, we can now represent a vast spectrum of business and disrupt innumerable industries. Let's see how that works in the real world.
With the combination of value and rules, we can now represent a vast spectrum of business and disrupt innumerable industries.– Dan Poulin , Technology Lead at Digital Surgeons
Mache Custom & Reebok: Defeating the Counterfeit Market with Ethereum
Recently both Mache Custom and Reebok have released collectible shoe lines taking advantage of blockchain technology. In the market of collectible shoes, counterfeit is rampant and costs the industry trillions. Both brands utilized a product from a silicon valley start-up named Chronicled that has developed a new kind of proof of ownership and authenticity for collectible goods. Its premise is simple — replace the typical printed proof of authenticity with a smart chip. With the help of an app, the key is then permanently tied to you on the Ethereum blockchain. Not only is the smart chip unable to be copied, but the record of ownership is unable to be tampered with.
This has implications beyond collectibles. Have you or someone you know ever purchased a used automobile and forgot to run a Carfax on it, only to learn later that the previous owner damaged it before changing hands? With records of ownership, sale, and even maintenance stored on the blockchain we gain unprecedented transparency in validating the history of a car or other item. Such records can even drive up the value of said car, as you can now solidly prove that it was driven by that famous driver or appeared in that popular movie.
Provably Fair Voting, Sweepstakes and Referral Programs
One of the easiest models for how a smart contract can encode sophisticated transactions takes the form of voting. A smart contract encodes that every account may vote on a question exactly once. Since the tallying exists as verifiable code, based on verifiable, tamper-proof records, the results have a very high reliability. Alternatively to voting, the smart contract can pick a winner at random, making it a sweepstakes.
Taking it a step further, we can imagine a referral system. Participants interact with the smart contract and it handles all of the details of who referred who, who gets paid out what amount. A special type of account (called an Oracle), set by the programmers of the smart contract, can be used to inform the contract of the clearance or validity of a referral.
UjoMusic: Reinventing the Music Industry
Perhaps the quintessential digital asset is the music download. UjoMusic is a startup that aims to change not only how music is paid for, but also how content creators are paid. All of the individuals involved in the creation of a track are associated with the music in a graph recorded on the blockchain. It can be publicly viewed and the information on who will receive what share of payment for what contribution is transparent. Furthermore, samples that make up the track can be purchased individually or in whole. All the while, no middlemen are needed to maintain an eCommerce platform, defend ownership, or decide on payouts to the content creators. Ownership of a song cannot be lost in an attack or outage, so there is no dealing with angry users who legitimately paid but lost access.
Looking to the Future; The Many Industries the Blockchain Will Soon Disrupt
Banking and Finance ✓
Healthcare and Biometrics ✓
Internet of Things ✓
Government ✓
Music & Video ✓
Arts and Entertainment ✓
Legal ✓
Intellectual Property ✓
Manufacturing and Supply Chain ✓
We believe all of these and more are about to be drastically changed by the blockchain revolution. The Fintech industry is abuzz with the possibilities and actively pursuing them already. As technologists and innovators, we see that the blockchain is no fad or framework of the week. We see it as being a foundational technology for the future.
"Enterprise, commerce, and the internet as we know it will be transformed for generations to come."– Pete Sena, Founder and Chief Creative Officer at Digital Surgeons
For now, blockchain technology is a new tool for enabling your business' online presence and engagement. It has a different set of strengths and constraints than the websites and apps that the industry has gotten used to. It's a new frontier, an experiment that began in earnest with Bitcoin and which has been brought to a whole new level with the advent of smart contracts. It will continue to play a large part in the way we work online moving forward, so it's worth getting your feet wet now to get an edge on your competition. IBM has already spun up an incubator dedicated to exploring just this, with other tech giants to follow suit. It's not a matter of if, it's a matter of when.
We at Digital Surgeons are incredibly excited by the opportunities that blockchain technology has to change not only how businesses engage online, but also change entire industries and eventually redefine human society.
The first generation of the digital revolution brought us the Internet of information. The second generation — powered by blockchain technology — is bringing us the Internet of value: a new platform to reshape the world of business and transform the old order of human affairs for the better.– Don Tapscott, author of Blockchain Revolution
We're looking for brands and partners with which to explore those possibilities together. Reach out and let's see if we can reinvent the way you do business.


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Recipe Review: How To Make Chicken Thighs in the Oven (Video!)
February 5, 2016 • 0 comments
This time of year we love oven baked recipes. Nothing like warming up the kitchen while creating the pleasant aroma of a home cooked meal through the home. This recipe video gives you a quick overview of a very simple and delicious way to cook chicken thighs in the oven. For a full step by step recipe guide be sure to click the link below.
- Prep Time:
- Cook Time:
- Servings: 2-5
- (2 pkgs) B/S Chicken Thighs
- Organic Imported Extra Virgin Olive Oil
- Bourbon Smoked Sea Salt
- Bourbon Smoked Pepper
- Stone-Ground Express Mustard
Click here for a step by step recipe guide.
Recipe by Rebecca Blumhagen & Kara Dykert for The Kitchn; Reviewed by Blaine Hitzfield


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Splice Machine Announces Version 1.5 of Hadoop RDBMS
October 20, 2015
It's a good day here at Splice Machine. Today we announced the release of version 1.5 of the Hadoop RDBMS. After listening closely to our customers, prospects and partners, we have used their feedback to improve our solution. We've added multiple enterprise-ready features that enable businesses to confidently replace their traditional RDBMSs, such as Oracle® & MySQL™, with an affordable, scale-out alternative that delivers 5-10x greater performance at one fourth the cost.
Now, businesses can experience even greater benefits of using Splice Machine to power real-time applications, run operational data lakes, or accelerate their ETL pipelines.
So, what's new with version 1.5? New features include:
- SQL Compliance
- Foreign Keys – Enables referential integrity between tables
- Triggers – Provides the ability to execute procedural code based on update, insert or delete actions
- BI Tool Compatibility (e.g. Tableau, MicroStrategy)
- Temporary Tables – Enables BI Tools to create temporary tables to perform operations on intermediate results
- SQL Functions – Deliver pre-built functions such as TOP N, LIMIT N, MONTHNAME, QUARTER, WEEK and NOW
- Incremental Backup – Provide recovery from data corruption by backing up data changed since last backup
- Window Functions – Provide FIRST, LAST, LEAD and LAG functions for advanced analytical queries
- Performance
- Enhanced Statistics – Collect more granular statistics required to choose best query plan
- Cost-Based Optimizer Improvements – Improves ordering of table access, selection of query plans, index selection, join algorithm selection (e.g., broadcast join, merge join, merge sort join, batch nested loop join)
- Subquery Unrolling – Converts nested subqueries in joins, accelerating certain analytical queries by well over 1000 times
We are particularly proud of the improvements to our cost-based optimizer, which dramatically improves performance on analytical queries. In 1.5, we have combined industry standards like SQL and ACID compliance with a modern scale-out architecture – giving businesses the ability to power real-time applications and analytics in a single, database platform.
Version 1.5 is also now available to download and try. For more information, please visit www.splicemachine.com.


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Young striker happy with victory over Exeter City at St James Park.All eyes were focused upon one man this afternoon as far as Mansfield Town fans were concerned - Rakish Bingham.
Signing for the Stags on deadline day on a free transfer, the 20-year-old forward came with a reputation to live up to and a crowd to embrace and, coincidentally enough, he accomplished both on his debut for the club.
This highly-rated prospect has been discussed on a national scale as a very promising young individual loaded with bags of potential. The attacker has spent much of his career playing for Wigan Athletic, however, having been loaned out to Scottish Championship outfit Falkirk last term, Bingham was released by the Latics at the end of the 2013/14 campaign.
Thrown straight into the deep end by manager Paul Cox on his debut, Bingham inspired and believed against Sky Bet League Two strugglers Exeter City and he exceeded expectations. With just a quarter-of-an-hour played, the youngster instinctively pounced on a rebound after Fergus Bell's initial shot was spectacularly saved by Exeter's keeper, Christy Pym. Bingham then had the opportunity to increase his tally on several occasions with the pick of the bunch occurring in the first half, however, his one on one effort on goal was foiled by the magic produced by goalkeeper Pym.
Speaking in his post-match interview following the game, Rakish went through the motions of his debut goal. He said: "The ball bounced, I can't remember who played it. The ball went on to Fergie [Fergus Bell] and he has then gone on to shoot. My first reaction was to just feed off it and the 'keeper has parried it and I just tapped it in to round off a real good goal."


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Boston Cop Called Henry Louis Gates Jr. A "Jungle Monkey"
Racism, we're solving it!
A Boston police officer was placed on administrative leave after he allegedly used a racial slur when referring to Henry Louis Gates Jr.
In a mass e-mail, Officer Justin Barrett, 36, called Gates a 'jungle monkey,' according to a law enforcement source.
Gates, a black Harvard scholar, was arrested at his home earlier this month on a disorderly conduct charge after he tried to budge open the door of his Cambridge home.
I can't possibly imagine why a black guy like Gates could possibly think that prejudice had any role in a police officer arresting him in his home. Unthinkable.


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Hispanic, Latino, Latinx: How to Cover the Fastest-Growing Student Group
Hispanic students, who make up the second largest racial demographic in schools today, are entering college in record numbers. But they are also dropping out of college at a far higher rate than white students. That reality has important implications for our educational and economic systems and the reporters who cover them, according to a group of researchers and experts gathered at the 2018 Education Writers Association National Seminar.
Hispanic student educational success "is not just a Southwest issue," said Luis Maldonado, chief advocacy officer with the Hispanic Association of Colleges and Universities. More than 3,313 school districts – spread across 47 states – have student populations that are at least 25 percent Hispanic, he said. "This is a middle of America issue," Maldonado said. "Our future labor force development will depend on Hispanics."
The percentage of Hispanic 18-24 year-olds enrolled in college soared from about 22% in 2000 to almost 37% today, according to statistics published by the U.S. Department of Education.
That massive increase in college enrollment has almost eliminated the college enrollment gap between Hispanic and white students
But six years after starting college, 35 percent of Hispanic students have dropped out without earning a credential, compared with just 27 percent of white students, according to the National Student Clearinghouse.
That so-called "achievement gap" has profound long-term economic implications, since most of the advantages in the job market go to college graduates. "College access means nothing if the students are leaving without a degree," said Michele Siqueiros, president of the Campaign for College Opportunity.
"The implications for students not graduating and student debt is huge," she said. "When you are mired in debt and don't have a degree, that is a serious situation," said Zoe Corwin, a higher education researcher at the University of Southern California.
The experts suggested the following four strategies for reporters interested in covering educational realities facing Hispanic students.
Are the students you're writing about Hispanic? Latino? Latinx?
It is important for journalists to understand that the subgroup is made up of people from many different countries and many different economic backgrounds – ranging from physicians escaping from communism in Cuba to indigenous farmers fleeing drug violence in Central America. Choosing the correct words to describe them is key.
Latinos, or those from Latin America, encompass a group from South America, Mexico, Central America, and the islands of the Caribbean. Latinos speak a variety of languages, though Spanish is dominant.
Hispanics are those from Spanish-speaking countries. Many governmental databases, such as the Department of Education's analyses of students by ethnicity, use the term "Hispanic."
While the Associated Press Stylebook approves using the words "Hispanic" or "Latino," a growing number of academics and advocates are using the word "Latinx" as a gender-neutral alternative.
"A lot of times we categorize Latinx students into one category, which is quite dangerous and unhelpful," said USC's Corwin.
Dig into the reasons for the achievement gap
Some Latino or Hispanic students come from families where no one else has attended college, and thus don't have a trusted relative who can assist them through negotiate the often convoluted admissions and financial aid processes.
Many Latino or Hispanic students are stymied by other systemic barriers, said Marcos Montes, an undocumented student attending the California State University, Los Angeles who is also a member of of the student government. As an undocumented Latinx student, he wanted a college that was close to his family. But his choices were further limited by "systemic barriers," Montes said. "There were not enough counselors," for example, to help him find a good, affordable college. Latinx students also don't always have access to AP and ACT preparation courses, which can make the academic progression to college more difficult, he said.
Affordability also plays a role. "Many Latinx students don't have a safety net," so one unexpected expense can force students to stop out.
A lack of diversity at colleges can also discourage students, Siqueiros said.
"The greatest indicators of college success are if Latinx students, and students of color, have mentors and supporters," she explained.
Highlight improvements
One way to push a story forward with a fresh angle is to focus on efforts to increase the completion rates of Latino students, the panelists said.
Hispanic-serving institutions, which specialize in serving Latino students, are a good place for journalists to look for examples of how best to meet the needs of those students, said Andrés Castro Samayoa, an associate professor at Boston College.
He said several Hispanic-serving institutions have begun to engage entire families – not just individual students – as a part of the college application process. Bringing parents and siblings to campus, and creating multi-lingual pamphlets and applications "can go a long way to increasing the belonging students feel at a college campus," he said.
And Ninfa Murillo, manager of the Michael and Susan Dell Foundation Dell Scholars Program, said a growing number of organizations are increasing student success by pairing financial aid with lots of advising sparked by data mining. Dell Scholars Program counselors check in with students frequently, and get alerted if the students show signs of trouble such as by missing classes or getting poor grades.
"For our model in particular, providing financial support is important, but the addition of data-informed support," has significantly improved student success, she said.
Mine the free data
There is a wealth of data sources to help journalists understand Latino student trends, panelists said.
College graduation rates by ethnic group and gender: Collegeresults.org, a site created by the Education Trust think tank, gives breakdowns of college graduation rates over four, five and six years for almost every four-year college or university in the country. It also allows you to compare colleges against competitors with similar student bodies and admissions standards.
DACA: The Migration Policy Institute has data on Deferred Action for Childhood Arrival recipient students.
Student debt and alumni earnings: Sara Garcia, a Center for American Progress policy analyst, recommends also taking a look at the U.S. Department of Education's College Scorecard, which provides data on the employment status and paycheck size of former students who received federal financial aid. It also provides data on how well each school's alumni are paying off their student loans.
Overall: Wil Del Pilar, Education Trust vice president for higher education policy and practice, said his organization has gathered several free and trustworthy data resources to help journalists.
Castro Samayoa also said the Center for Minority Serving Institutions at the University of Pennsylvania can create specialized datasets for journalists upon request. To request a dataset, email Castro Samayoa at andresca (at) gse.upenn.edu.


text:
This hostel is conveniently located in the center of Old Town Gdańsk, just 20 meters from the Motława. It offers free Wi-Fi in public areas, comfortable and affordable rooms. The hostel has a pub and a restaurant.
From the windows of simple but cozy rooms in the hostel Zappio stunning views over the old town and the shipyard.
Bed linen and towels are included in the price. There is ironing, washing, and hair dryers. Every morning, breakfast is served buffet breakfast is also included in the price.


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Anyone following Bristol-based producer Bengal Sound probably shares the opinion that he is the next producer out of Bristol to blow up on the underground.
At just 23 years old, Farhad Ahmed AKA Bengal Sound has already released with White Peach, his tracks have been cut to dubplate by the likes of Kahn and Zha, and he's played alongside Commodo and Bandulu Gang.
Working primarily within the worlds of grime and dubstep, with obvious influences from hip hop, garage and R&B among others, everything we've heard from Bengal Sound so far has shown serious levels of talent and creativity.
it comes as no surprise to learn that Farhad has been at the dials since the tender age of thirteen
While he might still be outwardly new to the scene, it comes as no surprise to learn that Farhad has been at the dials since the tender age of thirteen, after his brother's friend came over with a copy of Sony Acid.
He has just released his debut album Culture Clash on an extremely limited run of 100 cassette tapes (with individual download links). The 10-track project explores influences from UK dance music and old Bollywood soundtracks, and features artwork from Bristol artist and Bandulu affiliate Joshua Hughes-Games.
The 10-track project explores influences from UK dance music and old Bollywood soundtracks
Pre-orders sold out well before official release and if you didn't cop a copy, that's that. The album won't be released on digital and there won't be a reissue. Although you can hear album tracks Black Jacket, Black Water and Don't Go, plus a few more exclusives in Bengal Sound's exclusive guestmix for Nitelife NOISE.
The album follows his brilliant four-track Wushu Hand EP on White Peach Records, and he's already got a load more finished material up his sleeve. On Kahn's request, Farhad played a set at the Bandulu Records takeover at Trinity Centre last month using only his own tracks.
Culture Clash is the culmination of his final year project at dBs Music, where he is currently completing an Electronic Music Production degree. After working together previously, White Peach owner Zha offered Farhad the chance to put the album tracks out on White Peach, but via a series of releases.
'Usually in 140bmp, things come out as singles, but I wanted to do a longform project,' says Farhad. He decided to self-release on cassette, with White Peach stepping in as distributor.
Usually in 140bmp, things come out as singles, but I wanted to do a longform project
Farhad explains how this fruitful relationship with Zha first came about: 'I spoke to him initially through the Facebook page 4TheWax. He had done a mix for them and I thought "This is the kind of music I'm into. This is what I like doing." I messaged him on his artist page to ask if I could send him some tunes. I sent him two and he told me he was going to get them cut to dubplate.
'He told me to get a folder ready for him, which I didn't really think much of at the time. Then three months later he messaged me out of nowhere and asked if I had it ready. I sent it over and we started emailing. He asked for my number and gave me a call within a couple of minutes and said "Let's work on an EP".
Being in Bristol, where there's a big following for White Peach, it did help get me noticed
'I had to be quiet for a good five months about it, which was really hard. It was really successful and I didn't expect that – it just happened. Being in Bristol, where there's a big following for White Peach, it did help get me noticed.'
There's a level of clout that comes by association with White Peach, so passing up the opportunity to release with them in favour of a self-release, it's clear that Farhad has a very strong sense of how he wants to go forward with his music.
On why he chose cassette tape, obviously there is a cost associated with physical music, but Bengal Sound is drawn to the punk aesthetic of releasing on tape, a medium long-associated with DIY labels and artists.
Bengal Sound is drawn to the punk aesthetic of releasing on tape, a medium long-associated with DIY labels and artist
'I feel a piece of music needs to go hand in hand with a physical product. In terms of the way that the aesthetics of the tracks are, I feel like it's perfect for tape. It has a narrative going through each of the tracks and some of the lo-fi Bollywood samples work well on tape.'
While Culture Clash is in some ways a concept album, it doesn't differ hugely from his other tracks other than to hone in more closely on an idea that already informs his music. While it's at its best played from start to finish, you can listen to tracks individually, or move between albums tracks and his previous EP comfortably.
'Being from an Asian background, my family played a lot of South Asian music. Growing up with it, subconsciously it became ingrained in me. And being brought up in the UK with electronic music, I felt like I needed to merge the influences together to create one thing.
'I'm just doing tape for now because I want to put my focus on the physical copies. But later on, if I do a part two, maybe I will bring the digitals for it…'
The upward trajectory Farhad looks set to be on is a big one, especially given the fact that his set at the Bandulu Records takeover last month was only his third time playing out as Bengal Sound – his first being a White Peach label night at Cosies late last year. If he's not yet that well known by audiences, Bengal Sound clearly has an early seal of approval from some industry tastemakers that will inevitably have a trickle down effect.
'The way that the relationship with Bandulu came about was from me sending Kahn tunes regularly and asking for feedback and what he thinks. Every time I would send him something he would just say "Yep, I'm getting this cut. I'm going to play it out."
Bengal Sound clearly has an early seal of approval from some industry tastemakers
'I went to the Sequences Festival warm up party at Carhartt recently, where it was a surprise lineup. Kahn and Neek came through and he played two of my tracks. Obviously when he's mixing you can hear them bring the tune in slowly. I was looking at my mates, like "this one's mine". When one of my tracks plays I always look at the reaction – that's what I feed off, seeing what people think – and there was a good reaction from it.'
While he hasn't currently got any more live shows in the diary, Bengal Sound is definitely a name you're going to be hearing more of, with a string of releases already in the works.
'There are a few EPs lined up for this year and next year – I can't say any more than than that yet, but they're looking good. They're with labels and possibly another self-release. There is a project with White Peach soon, which is one thing I can say because I'm already affiliated. But there are a few others…'
In the meantime, you can hear Bengal Sound playing on 10Twenty radio every fourth Wednesday alongside his fellow Panum crew, Fellony and Unperson.
There are a few EPs lined up for this year and next year
Words by Rachel Morris
Photos by Dominika Scheibinger


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Customer Reviews:
Dust To Glory
Wow, all the reviews here are positive, I wonder if we saw the same movie. When it was coming out I was very excited. The only theatre in all of the south bay that carried it was in Manhattan villiage at the stinky, crappy , little theatre they have. This movie was boring! There was only 4 people in the theatre and it had only been out for a couple of days. Too much interviewing and going back to people. All the action is cut and it sucked! A few good parts with Mouse Mc Coy, and with JC shot from a chopper, but that was it for me. Took all I had not to walk out of the movie....
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Great History and Entertainment
'Dust to Glory' chronicles the history of the Baja 1000, showing exciting footage of race highlights and relating the challenges overcome by the organizers through the years in making it the premier off-road competition in the world. It is loaded with action and interviews with racing greats, including record 13 time overall Baja 1000 champion Larry Roeseler. Anyone will be tantallized by the challenge and drama of the longest, most challenging race on the planet today....
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Dangerous Film, BEWARE!!!
I first saw this video on Starz on dish network.
after I watched it, I had to order the DVD.
Be careful, after watching this video, I got the strange urge to jump in my car and go race around in the dirt for awhile!!!
In fact, I may never be the same until I've had an opportunity to race Baja Style...
Please buy this, and Please enjoy it!
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Inspirational, a great insight into an amazing race
This movie inspired me to start riding in the dirt, but even my friends who would never get on a bike enjoyed this movie. The helicopter and in car action shots are breathtaking, the pacing is spot on, the music fits, the people are interesting, and on and on. It really gives you a taste of what this amazing race must be like, and for someone like me, it changed my life....
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Dust to Glory
One of the best racing films I've ever seen. Saw it in a theatre the first time around. Very, very good....
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Really a great movie!
This was really a well produced movie! It told a great story and you really cannot believe what it all entails to race a race of this sort and even finish!
Did they try to cram too much into the movie as it really flashed before your eyes, and they jumped around quickly maybe covering too much material?
It really stuck me odd that after everything everyone went through, that 2nd overall didn't even get an interview at the finish. :-(
Well, I can say that I really did love the movie and I hope that we all don't have to wait another 2 1/2 more years for the second cut with all the other stories and video of the race.
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Being an off-road motorcycle fan, I was pretty sure I would like this movie, and of course I did. But this movie goes beyond that, not only with other forms of racing, but more importantly the personalities and families of the people behind the helmets. The whole family really liked it, even though they're not all thrilled with my passion for motorcycles. It's a must-see!...
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Must See
This is just the beginning of more movies like this that must be made. You always have one person saying that a movie was not done right, but they are never out there putting out a better one. This is a great movie, and a must see- If someone can do a better one, I will support that one too.... so let's see it....
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Format not readable
I live in Nevada -- within North America --- and the DVD format is not readable by two different machines. I am sending it back to Amazon, too bad I was looking forward to watching it....
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Spectacular, exciting and, strangely enough, moving
I originally got the DVD because of the Robby Gordon factor. I was blown away by the much bigger story of the race, Baja and all the competitors, particularly motorcycle riders Mike "Mouse" McCoy & J.N. Roberts.
McCoy is, by far, the most compelling and touching story. The original idea man behind the film, he convinced Dana Brown & Scott Waugh that the Baja 1000 was worthy of documentation. To add to the fun, Mouse decided to drive the 1000 mile race solo, a hard enough task for a driver with four-wheels and a roll cage, nearly impossible for a motorcyclist.
Roberts was the winner of the first Baja 1000 in 1967, as a co-driver with Malcolm Smith. His drive to finish the 2003 race, just weeks after picking up his first social security check, is both irrestible and funny.
Whether you are an off-road fan, a racing fan, a Robby Gordon fan or none of the above, if you have a heart, you will enjoy this movie, these people and their stories....
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Dust to Glory
Amazing video - edge of your seat excitement and great human interest stories. Even I enjoyed it - purchased for my husband - have lent ittoseveral motorcycle friends. ...
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Great DVD
I watch this DVD at least once a month. It is very inspiring and enjoyable. It makes you feel like you were actually in the race. It provides for a great experience and one that I wish I could live for real. Hats off to the produces of this documentary. Very good DVD, 5 Stars....
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Long Dusty Road
In the style of his father. Good movie.. About 20 minutes to long. ...
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Dust to Glory is a great movie.
This is one of the best off road movies I have ever seen. This movie definately gets the insight of the Baja 1000 and tells the story through the riders and drivers point of view, along with other point of views. This is my favorite movie, by far. ...
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Dust to Glory
absolutely loved it - the Baja 1000 is insane and this movie captures it fantastically ...
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dust to glory
picture guality is very poor but good entertainment they could have put more money into the production and had a classic...
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Greatest movie ever made!!!!
If you love racing you will love this movie. This is probably the greatest movie i have ever seen. Not just because of 800 hp racing through the desert, but the story in the film is amazing to. This isn't just a bunch of shots of big, fast trucks spliced together and music thrown over the top. Dana Brown really put his heart and soul into this movie. Awesome movie. I think everyone should see this, race fans or not. I've watched it over 10 times and it still gives me goosebumps every time....
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Fantastic movie
This makes you want to go out and race the baja. Great movie....
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Baja or Bust!
I thoroughly enjoyed this movie, very exciting. The cinematography was excellent, very difficult to shoot an action film of a live race for sure, but they pulled it off. I came away wanting to enter the race myself. I would recommend this to anyone who enjoys action films....
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Maybe a Little Too Much Talk /Camera Cuts, But Really, Really Good
I didn't know anything about the Baja 1000 before watching this film, so all the information about the race's history and the area it takes place in was helpful to me. If I had known about the race, I might have been wanted more actual racing action and less background. And some of the quick-cut editing gave more of a flash-"feel" to certain scenes rather than actual observation of the action. But those points are picky compared to the overall excellence of this film. I sat shaking my head in disbelief while trucks roared (and slid) at high speed a few feet away from spectators, separated only by a rope or some cones! The grueling, pounding trail rides of the motorcyclists were captured perfectly by on-helmet cams. The accidents, the humorous events, the near-death brushes -like the race itself, the filmmakers kept me on the edge of my seat, never knowing what would happen next. (The Added Feature segment of a cameraman riding a bike, trying to keep up with one of the racers, mile after mile, is worth the price of the movie. I ride motorcyles, but not off-road. The view through the helmet cam was incredible!)
I especially appreciated the repeated themes of family unity, friendship, and "never give up" that were presented again and again in the words and actions of many racers. The movie ended up being as inspirational as it was exciting, which I certainly didn't expect.
Great movie! (And again, the "extra features" are really worth watching; seeing what the filmmakers went through to finish their project was also surprisingly interesting and inspirational.)...
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Best movie ever maybe.
We've watched this 20 times already. And then I discoverd the "extra footage". I like to watch the helmet cam footage when there's nothing on tv at the end of the day. It's like you're riding it. Awesome....
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WOW! I just watched Dust to Glory... What a freakin awesome film! Two Thumbs up to Dana Brown. This film does a great job of covering the TACATE SCORE BAJA 1000 from beginning to end. Great camera angles and wonderful interviews from several teams from each class. I definately reccomend this DVD to anyone who is even the slightest bit intereted in Off-Road Racing and The Baja or just any gear head in general. It is by far worth every penny spent....
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Astonishingh Documentary on Baja 1000
Being a 10 year MX veteran from back in the late 70's and early 80's, I thought I knew something about Baja. I was wrong, this is an amazing race beautifully filmed.
I played the video for a group of friends one day over dinner, none of whom are involved in off-road sports and all were transfixed to the very end. My wife, who absolutely hates motorcycles, nonetheless talked about this video non-stop on the long drive home after watching it with our friends. For the first time EVER, I think maybe, just maybe, my wife found a spark of interest in off-road racing....
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Great One
This film is great, comes from a son of the maker of on any sunday....
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GREAT MOVIE! Seeing the Baja 1000
from the comfort of your couch but
yet you feel like you are there!
Makes me want to buy a vehicle to
race! Well documented, good interviews,
good footage, great music. Buy this!
if you love dirt sports!...
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text: Cutaneous T-cell lymphomas (CTCLs) comprise a heterogeneous group of extranodal non-Hodgkin lymphomas involving primarily your skin and mycosis fungoides is normally its most typical entity. change in overall immune system skewing with intensifying disease as well as the challenges of earning a timely medical diagnosis in early-stage disease due to having less dependable positive markers for regular diagnostics, also to discuss potential and established treatment modalities such as for example immunotherapy and book targeted therapeutics. colonization and elevated prices of infectious problems 33, 34. Latest data even claim that staphylococcal alpha toxin itself may Ly6c promote disease development through positive collection of Compact disc4 + tumor cells 35. Consistent with its opposing impact toward Th2-linked inflammation, the main Th1 cytokine interferon-gamma (IFN-) displays some efficiency in CTCL treatment 36. DY131 Nevertheless, various other cells, DY131 including fibroblasts, keratinocytes, and endothelial cells, are believed to market and augment a Th2 microenvironment in advanced-stage MF, additional attenuating Th1 immune system replies 37 thereby. DCs have the initial capability to induce principal immune system replies by activating na?ve T cells and therefore will be the central gatekeepers for the initiation of adaptive immune system responses 38. As shown recently, c-Kit +OX40L +Compact disc40L + DCs can foster the noticeable epidermis inflammation within skin damage by recruiting and activating harmless T cells which mechanism most likely provides essential tumorigenic signals inside the CTCL immune system microenvironment 30. In advanced-stage CTCL, the maturation of DCs is normally regarded as suppressed by Th2 cytokines 32. Significantly, immature DCs can induce tolerance by delivering antigens to T cells without suitable co-stimulation, hence fostering a tumor-tolerating (micro)environment instead of an anti-tumor immune system defense 39. Regularly, increased degrees of immature DCs are located in MF lesions, that will be an important system for tolerance against malignant T cells 40. Keratinocytes generate multiple chemokines, including CCL17, CCL26, CCL27, CXCL9, and CXCL10, that are potent chemo-attractants for many immune system cell populations. They make nerve development aspect also, which is recommended to be engaged in itch advancement, a typical indicator for CTCL 26. Mast cells might also be involved in CTCL pathogenesis, as their quantity correlates with disease progression 41. Similarly, myeloid-derived suppressor cells increase with advanced disease stage 42, and immunosuppressive M2 macrophages are known to promote tumor growth in various cancers 43 and could also play a role in CTCL 44C 46. Overall, there is a complex interplay between tumor cells and the cells microenvironment, which isn't yet elucidated fully. Medical diagnosis of disease In CTCL, hereditary markers are under extreme analysis as potential diagnostic equipment presently, but solo diagnostic biomarkers lack still. Hence, the integration of scientific morphology, histology, immune-phenotype, and molecular natural data remains needed for an accurate medical diagnosis 3. Appropriately, the medical diagnosis of CTCL is dependant DY131 on the mixture and correlation from the three pursuing assessments: (a) scientific observations, (b) (immuno)histological study of epidermis biopsies, and (c) extra laboratory tests such as for example stream cytometry of peripheral bloodstream and the evaluation of T-cell receptor (TCR) clonality by polymerase string response (PCR) 47. The parameter of large-cell change of MF cells, predicated on histological requirements, is situated in 56 to 67% of sufferers with advanced-stage MF 9 and associated with an intense disease training course with shortened success. Besides malignant T cells, an enormous variety of reactive immune system cells, including high amounts of nonmalignant T cells, accompany the malignant clone. Molecular and immunohistochemistry markers that are accustomed to diagnose MF are often detrimental markers presently, such as lack of appearance of, for instance, DY131 CD26 or CD7, but this kind or sort of aberrant surface expression displays considerable variability from case to case 48. Useful positive diagnostic markers lack for regular diagnostics even now. Importantly, the real lymphoma cells can be found in only little numbers during first stages of the condition. Hence, analyses of clonality (TCR rearrangement) tend to be falsely detrimental in early MF 49. Rea demonstrated that, for CTCL medical diagnosis, high-throughput sequencing was even more particular than gene PCR (100% versus 88%) but that awareness (68% versus.


text:
Ditch the Protein Bar and the Power Shake and Grab a Banana and Chocolate Milk Instead
Athletes reaching for sports and protein drinks to replenish carbohydrates and protein may benefit more by switching to chocolate milk and bananas, according to MNN.com.
Studies show that bananas are better to consume after a long period of exercise and chocolate milk is better for adding protein.
Researchers from Appalachian State University offers proof that bananas may be a better choice than sports drinks after exercise. They analyzed the blood of 20 competitive cyclists after they were given either water and bananas, water only, or a 6 percent sugar beverage (which is similar to a sports drink) every 15 minutes during a 47-mile (75-kilometer) bike ride, according to MNN.com.
The study showed that a banana might reasonably replace sports drinks for those who rely on carbohydrates to fuel exercise and speed recovery, stated nytimes.com.
The study found that a banana, with its all-natural package provides comparable or greater anti-inflammatory and other benefits for athletes than sports drinks. However, there may be a downside, and it involves bloating, explained nytimes.com.
"Consuming bananas with water during exercise has several advantages for athletes and fitness enthusiasts above those linked to regular sports drinks, including stronger anti-inflammatory effect, better nutrition and improved metabolic recovery," study author Dr. David Nieman, director of the Appalachian State University's Human Performance Laboratory, as reported by MNN.com.
Sports drinks are still an option, but Nieman and his team believe bananas offer more to athletes.
Athletes have been taught to refuel with protein immediately after a workout. Most of these athletes immediately look to refuel with an easy, portable protein shake. However, just drinking protein won't replenish glycogen stores. After an intense workout, it is recommended to drink low-fat chocolate milk. One cup of low-fat chocolate milk takes over 30% of your daily recommended calcium, 25% of your daily recommended vitamin D, and phosphorus.
Chocolate milk helps with muscle gains. Research shows that a mix of slow and fast digesting protein is superior for lean body mass gains. Milk is 80% casein, 20% whey. Chocolate milk also increases fat loss as it decreases hunger and thus helps you to lose fat, according to stronglifts.com.
A third benefit of drinking chocolate milk after working out is the recovery it grants. Chocolate milk is a fluid and has electrolytes. Research shows milk is superior to water and sports drinks for rehydration post workout, according to stronglifts.com.
An additional benefit of switching to chocolate milk and bananas to replenish carbohydrates and protein is the cost savings. A pack of chocolate milk can cost around $5 and bananas are $0.56 per pound as opposed to a pack of protein bars which can be as cheap as around $6 and protein shakes which can be $10 or more.