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The story of Queen Victoria and Abdul Karim: 60 seconds with Shrabani Basu
At the time when the British Empire was at its height, a young Indian clerk called Abdul Karim gained the affection of Queen Victoria, quickly becoming her closest confidant and teacher. In her talk at our York History Weekend this November, Shrabani Basu will tell the story of their controversial relationship, which caused a storm in the royal court but survived the best attempts to destroy it.
Ahead of her talk, 'Love in the Time of Empire, the story of Queen Victoria and Abdul Karim', we caught up with Shrabani to find out more…
Q. What can audiences look forward to in your talk?
A. They will hear about a hidden story from history, about the unusual relationship between Queen Victoria and her Indian servant, Abdul Karim.
Q. Why are you so fascinated by this topic?
A. I found it fascinating that a young Indian Muslim man was at the centre of the royal court at a time when the British Empire was at its height. It is a part of history that the royal family tried to destroy after Queen Victoria's death.
Queen Victoria, Empress of India, pictured in Bombay, Mumbai in an illustration from the magazine 'The Graphic', c1877. (De Agostini/Biblioteca Ambrosiana/Getty Images)
Q. Tell us something that might surprise or shock us about this area of history.
A. I saw a different side to Queen Victoria; she was not the dour woman dressed in black that we are used to. She was ahead of her time. She had no prejudices of race or class. She defended the Indians against the prejudices of her household, family and the government. She also learnt Urdu from Abdul Karim and could read and write in Urdu by the end of her life.
Portrait of Queen Victoria. (De Agostini/Biblioteca Ambrosiana/Getty Images)
Q. What is the hardest question you've ever been asked about your area of expertise?
A. Whether I have ever had to lie to get documents or access! Thank goodness, I haven't.
But I did sneak into a building pretending to be a resident when I was researching my book Spy Princess: the Life of Noor Inayat Khan. The building was 84 Avenue Foch, Paris, and it was used as a prison by the Gestapo. I knew that Noor Inayat Khan, the SOE agent (Special Operations Executive), was imprisoned in the attic rooms. The building is a private building now. I wrote formally asking for access, but never got a reply. Once I was outside the building, I just had to go in. It is one of those gated Parisian buildings. I saw a resident entering, and just followed him in. The marble staircases were exactly the same as from that period. It made me shudder to think that the residents had no idea what the building was used for.
Q. If you could go back in time to meet one historical figure, who would you choose and why?
A. Noor Inayat Khan. She is my heroine.
Britain's Princess Anne unveils a sculpture of Noor Inayat Khan. Dubbed the 'spy princess', Kahn was sent into occupied France in the Second World War to help the resistance. (LEON NEAL/AFP/Getty Images)
A. I would like to be in the room where Jawahar Lal Nehru made his famous 'Tryst with Destiny' speech at the stroke of midnight on 15 August on India's Independence Day. It still brings a catch to my throat when I hear it. Incidentally, my birthday also falls on 15 August (not 1947), so it's a special day for me.
Q. What historical mystery would you most like to solve?
A. Jack the Ripper
Illustration shows the police discovering the body of one of the victims of Victorian serial killer, Jack the Ripper, c1888. (Photo by Hulton Archive/Getty Images)
Q. What job do you think you would be doing now if you weren't a historian/author?
A. Anything that involved travel. A diplomat maybe, or a history guide.
Shrabani Basu is a journalist and author whose books include For King and Another Country and Curry: the Story of the Nation's Favourite Dish. She will be speaking about Queen Victoria and Abdul Karim at BBC History Magazine's York History Weekend on Sunday 26 November.


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Healing in the History of Christianity
Healing in the History of Christianity
Healing is a persistent theme in the history of Christianity, threading its way over time through ritual practice and theological belief, and across space through the sprawling, heterogeneous terrains of Christian community life and missionary activity. To focus on healing in the history of Christianity, as this book does, is to attend to important elements of continuity amid the jumble of competing doctrines, innumerable churches, disparate behaviors, and historical developments.
When I embarked on this book, I did not anticipate the extent to which I would come to see Christianity as a religion of healing. My initial goal was to explore the history of Christianity without getting lost in the process. I chose healing as an organizing focus because of current interest in the topic, which I hoped would make my study interesting to others, and because new ways of thinking about religious practice and experience prompted me to take claims to religious healing more seriously than I had before.
Although I was prepared to take the reality of Christian healing seriously, I did not expect to find the history of Christianity so laden with its signs. I thought I would find the emphasis on healing apparent in the ministry of Jesus marginalized in Christian history, shouldered out by theologians and church authorities intent on marching people toward salvation in heaven, but kept alive, on the edges of ritual practice and belief, by common people desirous of protection and escape from sickness, misfortune, and death. I also . . .

subset: commoncrawl


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Trump's Final Border Solution
This past weekend (4-7-2019), brought another time frame in the disorderly and chaotic administration of Donald J. Trump. Something ominous happened, and we are now seeing the real problem with this presidency; it's Trump himself.
With the dismissal of Department of Homeland Security Secretary Kirstjen Nielsen via a Trump Tweet, we see a fuming Chief Executive demanding that our border authorities continue to separate migrant children from their parents as a deterrent to crossings. Trump views US Immigration and Customs Enforcement (ICE) and US Customs and Border Protection (CBP) as his own personal armies. And much like the "thought police" in George Orwell's book 1984, or the TV dystopia Republic of Gilead as portraited in the Hand Maiden's Tale, Trump thinks he can use these two forces to execute his agenda, control thought and push away his imaginary crisis.
Nielsen probably warned Trump that some of his actions would be at least unethical and, at worst, against the law. The Donald truly believes he soars above the law and can do whatever he wants. His final solution on the border will be to station the US Military, ICE and CBP soldiers with guns to shot those who want to enter our country. If you find this rather disturbing, think about this story.
In 2012, a CBP agent named Lonnie Swartz was accused of shooting through a border fence in Nogales, Arizona killing 16-year-old José Antonio Elena Rodríguez, who was on the Mexican side of the border. The agent fired 14 to 30 shots and ten of those bullets hit the teen. Swartz was acquitted of manslaughter. Trump knows this and so does Stephen Miller, the architect of Trump's immigration rants. They have exacerbated a problem, massaged it into a crisis, and now are claiming the only solution is closing the border, which will cause massive economic harm to America.
All the bellicose verbiage from Trump has given the people movers in Mexico a firm sales pitch to make more money. They tell their Spanish speaking brothers and sisters that they must move now before Trump closes the border. Trump's chest beating has promoted more immigrant crossings. Stupid.
Donald Trump doesn't care about families seeking asylum. He has clearly stated he wants Congress to end asylum opportunities for immigrants. This is not new. In the summer of 1942, the US government turned away Jews who were seeking asylum from Nazi oppression and death. Some landed in the Dominican Republic. Others were simply sent back to face "their own problems." Trump has gone all in with his anti-immigrant racist viewpoints and believes this will help him get a second term in office.
The rich irony here comes from the man who is manipulating Trump, Stephen Miller. According to Wikipedia, Miller grew up in Santa Monica, California. His mother's ancestors had immigrated to the United States in the early 1900s from Belarus, escaping the anti-Jewish pogroms in the Russian Empire. When his great-grandmother arrived in the US in 1906, she spoke only Yiddish, the historical language of the Ashkenazi Jews of Eastern Europe. However, despite the family's poverty, as was typical of many immigrants, most of the family learned English, worked hard, and opened businesses in Pennsylvania that became successful—"the classic immigration success story".
Mr. Miller obviously has no moral connection to immigrants because of his half-baked ideology that paints Trump as a messiah and the embodiment of a movement where one cannot question the authority of the president. How do we know this? Because he said so on TV. There is no reason to believe that Trump, if left alone, wouldn't come to these same conclusions, but it really does feel a lot like Adolf Hitler, doesn't it?
And just before we posted this article, news arrived that Trump has fired the head of the Secret Service. That person reports to the head of Homeland Security and was a Trump appointment. This is just another example of his terrible vetting, negligent management style and lack of planning and focusing his people.
I would suggest that we all keep our eyes on Donald Trump in the coming months. He will probably not deal with the truth in the Mueller report. That's likely to spark another lie fest. Trump will stonewall Congress on his tax returns, which will prompt thinking Americans to ask the questions, "What is he hiding? Why did he say he would release them? Why does he keep saying that he cannot release his tax returns because he is under audit?" That, by the way, is a lie.
Trump is going to do some really bad things at the border and those who stay silent, will claim their place with those who stood by when the government interred Japanese Americans and those who were mute when we turned Jews away at our ports. Some people supported Richard Nixon's lies and validated his immoral bombing of women and children in North Vietnam. For those who tell me that I should respect the president, I say, he's not a king. He's just a president. Why should we stay silent when a president crosses the line of law and order? Trump is a grand liar and a mentally ill dictator in the making.
Gold, God, Guns & Goofballs shows how we've wasted our GOLD on bad wars and corruption. While GOD is there for many people as a spiritual enrichment and the provider of glowing feelings, the truth is just praying and believing will not change our major arc. We don't determine who gets a GUN. We aren't sure if we have paramilitary groups ready to storm the White House or a White Castle. There is no control of weapons. The GOOFBALLS with the power constantly try to manipulate us into spending more money on bombs and tanks and wars. When all of our institutions are infected with neglect and fall in disrepair, we will only have ourselves to blame. This book is not an antidote for the left or right, it's an accelerant to move the middle off their collective asses to go do something positive for America.
Get the Kindle Version HERE. Or order your paperback edition HERE.


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Sorry about the lack of posting lately. We've been busy and out of town. I'm back now with a few days off still until I go back to work (Mardi Gras vacation), so I've got some time to catch up. I'll probably create more than one post today.
So back to Alicia Silverstone's "The Kind Diet". I had some sweet brown rice that I'd gotten at the Asian market nearby, so the Barley with Sweet Rice and Corn sounded perfect. The combination of barley with the rice was delicious. (I still need to buy/make Gomashio) I served this with my Collards and Cabbage.
Tanya's Collards and Cabbage:
1 huge bunch collard greens, washed and torn into bite-sized pieces
2 cups shredded green cabbage
2 tbsp rice cooking wine/mirin
1/2 onion, chopped
2 tsp minced garlic
soy sauce
sesame seeds
Saute the onion in a little water until soft. Add the garlic and stir/cook for another minute. Add the collards. Cover and cook for about 2 minutes. Add the cabbage. Cover and cook another minute. Add soy sauce to taste and the rice wine. Add spices to taste. Serve over cooked grains.
I made my own pizza again a few days ago. I finally bought a pizza crisper(pan) and that did the trick for keeping a really crispy crust all over. I also pricked the crust all over with a fork, before pre-baking it for 5 minutes or so in the oven. It was soooo good, and crunchy, yay! You can find my original pizza recipe here.
Enjoy! I'm out of vegetables (what???), because we were out of town and the next farmer's market isn't until Saturday......sigh.....I did break down and buy some broccoli at the store today.
Hope you all had a good Mardi Gras!
Eat smart,
I'm a classical musician and a vegetarian. I eat mostly a plant-based diet and love finding new vegan & raw recipes to try. Blogging is a new passion of mine and I try to post as often as I can (between rehearsals and concerts) Eat smart!
Thursday, February 18, 2010
Greens and Sweet Rice
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Hold up, a new Spiritualized album came out this week. I haven't listened yet but come on, we all know how its gonna go down.
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From the 24th to the 28th of March, 13 researchers met in New Hampshire to advance Arctic tundra research. Attendees (plus three remote participants) tackled one of the largest drone-imagery datasets ever compiled for high latitudes – all contributed from field teams using similar protocols – to commence the High Latitude Drone Ecology Network (HiLDEN, https://arcticdrones.org/) data synthesis.
Drone data are allowing scientists including members of the HiLDEN team to capture a landscape-level perspective on the rapidly changing Arctic.


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#4018-23: 40 tons/per wheel capacityfor steel mill torpedo cars and other extra heavy railcars.Weight: 6,050 lbs.
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SINGLE HALF DIAMOND for approaches to buildings, weigh scales, unloading pits.for 1-way rerailing
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Recently, Wikia rolled out an update to the permission management system for Wikia wikis: http://community.wikia.com/wiki/User_blog:BertH/User_rights_updates_for_Forum_and_Message_Wall
Furthermore, now that I am head crat, I would like to institute some changes about how people get and keep elevated privileges on this wiki. We need to accommodate the new usergroups, and we need to do something about the large number of inactive elevated-privileged users, but without creating any major means of corruption. With that in mind, I propose that we update the permission groups on this wiki. We will use this thread to vote on my proposed changes "I may be head crat, but this is still a democracy." Here are the proposed changes:
We will have 4 usergroups:
Everyone on that list will have all of the privileges of their rank, plus all of the privileges of the preceding ranks. In fact, the only difference for this policy is that it accommodates the new Moderator privilege group.
Next, I want to instill a new policy about staying in power. We have an absurd number of inactive users who have special privileges. I want to fix that, but without creating any major corruption potential. With that in mind, I propose this policy:
"Once every month, a list must be gathered of every crat, admin, and moderator who has not contributed to the wiki within the last 6 months. If there are any within that list, the one who has gone the longest without contributing will be demoted to a standard user. If all of the elevated users have contributed within the last 6 months, nothing will happen. This will happen once a month, to prevent too much circulation."
We will have until February 1st to vote on the updated policies. Please post all comments about the updates here.


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Preparing for IIT-JEE? Well, this article is for you. This is one of the leading career options to choose from. The exam will be conducted by NTA (National Testing Agency) in 2019 before it was conducted by the CBSE Board. JEE Mains is applicable for admissions to NITs, IITs, and CFTIs and the candidate should have secured at least 75% marks for the general category and 65% for SC/ST in class XII.
You may have been preparing for the exam a long ago, but keep in mind that you are going to compete with the best brains of the nation so prepare it in the best possible way you can. The smarter you prepare the better result you will get.
So, one of the most important parts of preparing for the exam is to attempt online mock test series to know that how well you have prepared and how much more effort you need to put in to get the desired result.
Here are some key benefits of online test series for IIT
1. Know-How to Manage Time Efficiently
Time management is very crucial while you are sitting in the exam because you will be given a limited time to attempt several questions that sometimes become a difficult task and you may run out of time with some unattempted questions left because stress is related to this while you are in an examination hall. With the help of online test series, you can manage to complete the test in the given period.
You can increase your speed and accuracy by practice. This will help you in attempting all the questions and you will peacefully finish your exam.
2. Immediate Result
Attempting an online mock test series helps you evaluate your knowledge by displaying the result immediately after the exam that you won't have to wait even a day. With this feature, you can get to know about your weaknesses and strengths. Then focus more on your weak points and turn them into the strengths which will help in getting better results.
3. No Chance of Cheating
As parents can fully rely upon the results because there is no way of cheating out in the online mock test because the answers are shown only after the submission of the test and the result and every time there is a different set of question paper mean that every question is no more repeated.
4. Flexibility in Time
While giving the online mock test, you don't have any compulsion to follow the strict schedule. You can give the test anytime you want to. You just need a personal computer or a laptop and an internet connection. No matter where you are and what is the time, it all depends upon you.
5. Convenient
As I have mentioned above that the place is no matter, so here we can clearly understand that you don't need to travel anywhere like any institute, computer cafe(if needed), etc to appear for the test. So you can save these expenses also and the time spend on it can also be utilized appropriately. In other words, it is an eco-friendly way too. Also, the fees of the online mock test are not so much. You can easily manage to buy it online with online payment mode.
6. Helps You Feel More Confident and Motivated
The online mock test is almost like the real test with all the instructions as per followed during the real test. Most of the students got nervous during the exam and due to this their productivity level goes down. So, don't worry, your chances of getting stress or nervous will be reduced. You will easily adjust yourself according to the given instructions and you will be able to perform very well. Most of the students got nervous during the exam and due to this their productivity level goes down.
Conclusion: Online test series for IIT
In a nutshell, I would like to suggest to all the students who have the passion to achieve success in JEE exams, must go for online mock tests along with your daily preparation schedule, as per the benefits are explained above. So, it is the only time for pressing the right button.
"Success comes from hard work, learning from failure, loyalty, and persistence"
All the Best!
Want to Join Online Mock Test Series For IIT JEE? Write to us at firstname.lastname@example.com / call us at 95.5511.5533


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Supreme Court Considers Affordable Care Act Religious Exemption Rule
On Wednesday, the Supreme Court will consider yet another case regarding whether employers can decline to cover contraceptives in their health care plans. Reproductive rights groups warn that depending on the outcome of the case, tens of thousands of American women could lose vital contraceptive coverage. The case, Little Sisters of the Poor and Paul...
New Form of Birth Control Being Tested for Approval by FDA
Ovaprene, a new form of birth control, is being tested and would be the first barrier form of contraception to be released to the market since the internal condom in 2006. In recent years, most forms of contraception created are hormonal, including the birth control pill, the shot, the ring, and the patch. Hormonal forms...
Birth Control Delivery Startups Threatened by CVS Proposal to Cut Reimbursement Rates
Birth control mail order services are in danger after CVS indicated it would cut reimbursement rates for home delivery, putting members in jeopardy of losing access to their birth control due to rising costs. #CVSDeniesCare began trending on Twitter Thursday after birth control mail order service Pill Club posted a public plea to the pharmacy...
Federal Appeals Court Blocks Trump Administration's Birth Control Exemptions
Last Friday, the 3rd U.S Circuit Court of Appeals upheld a nation-wide injunction to block the Trump administration from enforcing new rules that would allow employers to obtain exemptions from an ACA requirement that insurance must cover women's birth control. This decision upheld a district court decision issued in January that blocked regulations issued by...
Study Proves that Global Gag Rule Increases Unplanned Pregnancies
The medical journal The Lancet released a study on Thursday examining the impact of the global gag rule, officially known as the Mexico City Policy, on the rate of abortions in sub-Saharan Africa. Researchers discovered that rather than decrease the amount of abortions as anti-choice advocates advertised, the policy increased abortion rates by approximately forty...
University of Notre Dame Health Insurance Will No Longer Cover Birth Control
Early this week, the University of Notre Dame announced that beginning in January 2018 the university insurance plan will no longer include birth control coverage for students except in cases where it is being used "for a medical condition and not as pregnancy prevention."
Tom Price, Opponent of Abortion and Contraception Access, to lead Department of Health and Human Services
He has a 100 percent rating from the National Right to Life Committee and a zero rating from Planned Parenthood.
Zika Virus Raises Need for Increased Access to Reproductive Healthcare
As the Zika virus spreads, at least five countries have advised women to delay pregnancy, advice that many women's rights advocates have criticized as unrealistic and offensive given restrictive abortion laws and the inaccessibility of birth control in many of the affected areas.
Judge Rejects Order to Block Catholic Hospitals Denying Women Tubal Ligations
A San Francisco Superior Court judge declined to issue an emergency order that would prevent Mercy Medical Center, a Catholic hospital, from refusing a women's request for a tubal ligation.
New Study Shows More Women Choosing LARCs
Long-acting reversible contraception (LARC) is the "fast-growing" form of birth control in the United States, according to a new report released this month.
Teen Births In Colorado Dip 48 Percent Thanks To LARCs
Just five years since Colorado introduced an innovative family planning initiative providing little to no-cost long-acting reversible contraceptives (LARCs) to low-income women in 68 clinics, the Colorado Department of Public Health and Environment announced a 48 percent decline in teen births and abortions statewide.
Women Are Saving Hundreds of Dollars on Contraception Following the ACA's Implementation
Since the Affordable Care Act took effect, women have saved dramatically on birth control and emergency contraception.
Black Communities Overwhelmingly Support Reproductive Rights
A new study has found that the majority of Black men and women believe in a woman's right to choose and want women to have access to abortion care and contraception.
Planned Parenthood Cleared to Apply for License in New Orleans
The Louisiana health department has allowed Planned Parenthood to apply for a license to provide abortion services in New Orleans, backtracking on a previous rule that barred the organization from opening a clinic in the city.
New York Attorney General Moves to Expand Access to Contraceptives
New York Attorney General Eric Schneiderman introduced the Comprehensive Contraception Coverage Act of 2015 last week to enhance the availability of contraception for New Yorkers.
Obama Administration Clarifies ACA Birth Control Benefit After Reports of Conflicting Policies
The Obama administration announced yesterday in new guidance to health insurance companies that insurers are obligated to cover all forms of birth control under the Affordable Care Act.
US Ranks 16th Worldwide on 2015 Social Progress Index
The 2015 Social Progress Index assesses and scores countries worldwide across three categories: Basic Human Needs, Foundations of Wellbeing, and Opportunity.
DC City Council Unanimously Approves Reproductive Health Anti-Discrimination Bill
Wednesday, the Washington, DC City Council unanimously passed a bill that will prohibit employer interference in the reproductive health decisions of their employees. The Reproductive Health Non-Discrimination Amendment Act of 2014 was first introduced by DC Councilmember David Grosso (I-At Large), just ahead of the Supreme Court's ruling in favor of for-profit retail chain Hobby Lobby this...
Federal Appeals Court Rejects Challenge to Affordable Care Act Birth Control Benefit
In a victory for women's health, a unanimous panel of the US Court of Appeals for the DC Circuit on Friday rejected a challenge to the Affordable Care Act (ACA) contraceptive coverage benefit brought by Priests for Life, the Roman Catholic Archbishop of Washington and other religiously affiliated non-profit organizations.


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A Manchester, New Hampshire man was arrested Thursday night following an officer-involved shooting.
Justin McInnes, 29, was arrested after he allegedly accelerated his car toward officers in an attempt to harm them as they were conducting surveillance on him. The encounter prompted officers to open fire in an effort to stop McInnes, according to police.
The shooting happened at 9:20 p.m. near the intersection of Flaherty Lane and Hecker Street.
In-depth news coverage of the Greater Boston Area.
Officers considered McInnes armed and dangerous at the time of the surveillance. After they saw him exit an apartment complex, they approached themselves and ordered the suspect to show his hands.
"We had investigators conducting surveillance at an address they knew he was at, with the belief that he may have been armed and dangerous," police Lt. Brian O'Keefe said.
McInnes allegedly refused to comply and instead got into a 2007 Jeep Cherokee, which he used to drive at the officers, police said. The suspect's vehicle broke down as he drove toward Main Street, which gave police an opportunity to detain McInnes.
"He came at them and gunshots occurred," O'Keefe said.
McInnes was taken to a nearby hospital with non-life-threatening injuries he received from broken glass and other shrapnel from his car, according to police. He was arrested after his hospitalization.
Officers said they recovered a handgun in his vehicle.
"We're just fortunate that the officers didn't get hurt and the suspect sustained minor injuries from most likely fragments of the windshield or parts of the vehicle," O'Keefe said.
Manchester police said McInnes was wanted on several warrants, including one stemming from a road rage incident in July in which he allegedly tried to hit another car. He had another oustanding arrest warrant related to a police pursuit in Manchester on Wednesday.
In addition to the outstanding warrants, McInnes was charged with three counts of attempted murder felon in possession of a firearm and fugitive from justice.
No officers were injured during the confrontation.
McInnes is scheduled to be arraigned on Friday afternoon. It is unclear if he has an attorney.


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What prevents you from doing more to protect the water resources in your community? Is it simply a matter of insufficient funds? Do you have staff within your organization who can plan, implement and maintain watershed protection and restoration projects if you have the funding? Do you know who to go to with questions or for guidance about reducing nutrient and sediment loads in your community?
In my experience, it's a little bit of all of these that keeps local governments from doing more. This is the message the Local Government Advisory Committee to the Chesapeake Executive Council delivered to the Chesapeake Bay Program leadership when they met on Aug. 7 in Baltimore. It's the same message that the LGAC has been raising for years, but as I told the Executive Council, it's time for action!
For the second year in a row, the LGAC called on the Executive Council to conduct an evaluation of the nature, sufficiency and scope of technical assistance resources and programs available to local governments for the purpose of establishing new, re-tooling existing, or expanding state and/or federal programs to achieve greater effectiveness in watershed implementation plans.
To get the ball rolling, the LGAC will be convening our annual local government forum where we bring in outside experts to help us develop detailed recommendations to address a particular challenge facing local governments. This year we'll be focusing on the issue of meeting local governments' needs for technical assistance.
We have to find a way to scale up successful models for technical assistance delivery and we need to make sure local governments have the internal capacity to take advantage of these services.
We also need to evaluate what's being done already, including looking at pilot projects like the recently launched "circuit rider" program on Maryland's Eastern Shore, and we need to institutionalize the delivery of watershed technical assistance to local governments.
This may mean establishing new technical assistance delivery systems using organizations like Virginia's Planning Development Councils or Pennsylvania's Councils of Government. But, it may only be a matter of re-tooling, re-purposing or expanding existing programs.
The recommendations we come up with at the forum will help inform the states, who must include strategies for addressing these types of gaps in their Phase III Watershed Implementation Plans.
During listening sessions in Pennsylvania and Virginia over the summer, LGAC members heard suggestions for using workforce development and restorative justice programs to address local staffing gaps. Some of the ideas we heard address other critical issues that local officials are grappling with: the opioid epidemic and reducing the rate of recidivism. The LGAC included this in their annual recommendations to the Chesapeake Bay Program leadership, suggesting that state and federal workforce development programs be used to train targeted groups, including people incarcerated for low-level crimes, veterans and other disadvantaged populations, to perform such functions as installing and maintaining green infrastructure.
At the Maryland Association of Counties 2018 Summer Conference in Ocean City, Robert Green, director of the Montgomery County Department of Correction and Rehabilitation, shared his experience with employing restorative justice while meeting the county's needs for public services. According to Green, participants in the restorative justice program have provided more than 60,000 hours of service in the community over the last couple of years. We think this is a win-win opportunity that should be explored further.
So, stay tuned and make sure you get a seat at the table in the Phase III WIP process in your state so you can advocate for the services you need to be successful watershed stewards.
Meanwhile, the members of the LGAC will continue offering the Chesapeake Bay Program leadership our best advice on policies and programs that enable local governments to engage in protecting and restoring the Chesapeake Bay Watershed.
Bruce R. Williams is chair of the Chesapeake Bay Program's Local Government Advisory Committee.
Views expressed by opinion columnists are not necessarily those of the Bay Journal.


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Two 24-year-old men were the victims of a gunpoint robbery on Sunday, Nov. 18.

The swarming happened at about 2:30 a.m. near Main Street and Danforth Avenue.

Police report a group of five suspects approached the victims.

One of the suspects then allegedly produced a handgun and punched one of the victims in the face before demanding both men hand over their personal property.

That same suspect reportedly searched the victims' pockets and removed their belongings as the other four suspects stood by.

All five suspects then fled the scene eastbound on Danforth Avenue with the victims' iPhone, identification, jewelry and a quantity of cash.

The victims were not injured.

The first suspect is described as a white male, about 26 years old, and 5'9" with short brown hair and brown eyes. The other four suspects are only described as white males, about 27 years old.

Anyone with information is asked to contact police at 416-808-5500, Crime Stoppers anonymously at 416-222-TIPS (8477), online at www.222tips.com, or text TOR and your message to CRIMES (274637).


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VICTORIA – The UVic Vikes women's soccer team threw everything they could towards net in the final twenty minutes of play but couldn't overcome the hole they found themselves in, in an eventual 2-1 loss to the host Trinity Western Spartans at the Canada West Championship Game on Nov. 4.
"They were ready to go and so were we but we had one lapse and it was enough for them to score," said Vikes head coach Tracy David. "They scored another one, but credit to our team, they battled and got the game to within one."
Second-year forward Georgia Bignold scored the lone goal of the game for the Vikes with Stephanie Badilla Gutierrez picking up the assist. Kathryn Harvey and Brooklyn Tidder were the goal-scorers for Trinity Western.
Puck Louwes made three saves in the Vikes net as the team surrendered more than one goal in a game for just the third time all season. Christina Oliverio also made three saves for the Spartans.
The Spartans made their home field advantage pay off almost immediately after the opening whistle.
A ball was sent into the box by the always-dangerous Rachel Hutchinson and Harvey managed to run between two Vikes defenders and tuck the ball underneath a diving Louwes.
For a team that had only trailed in four of their previous 16 games, the Vikes responded well to the adversity of being down early in a hostile environment.
The team slowly fought their way back into the game and were able two record two shots and couple of dangerous corner kicks against an extremely formidable Spartans defence in the half.
The Spartans doubled their lead in the 52nd minute of play when a ball was put into the Vikes 18-yard box from a free kick. Tidder and a Vikes defender jostled for the ball but it was Tidder who came up with it and fired the ball past a helpless Louwes.
A goal in the 72nd minute from the Vikes almost sparked the comeback.
A beautiful, curling free kick from Badilla Gutierrez was sent in back post and Bignold rose to the ball with a beautiful header to power it past Oliverio.
The Vikes pressed for an equalizer throughout the remainder of the game but the Spartans did well to choke the game off in the midfield and deny the Vikes anymore clear-cut scoring opportunities.
The loss was just the second of the season for the Vikes, their only previous defeat came all the way back on Sept. 9 and it was by an identical 2-1 score-line to these very same Spartans.
"Trinity are a very good team and I hope we get to play them again but they played really well tonight," said David.
The Vikes were gunning for their first Canada West Championship since 2008 but instead will head to the U SPORTS National Championships, hosted in Winnipeg, MB from Nov. 9-12, as the No. 2 seed from the conference.


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text:
Northside dropped its third straight game as the Grizzlies were defeated at Cabot, 35-23, in 7A-Central action on Friday.
The Grizzlies (5-4, 2-4) can still get a first-round home playoff game with a win at Mayo-Thompson Stadium next Friday against crosstown rival Southside.
Southside is currently fourth in the conference, while Cabot (4-5, 2-4) and Northside are tied for fifth. Cabot plays at 7A-Central leader and No. 1 ranked North Little Rock next week.
Northside quarterback Derrick Wise completed 12-of-18 passes for 172 yards and two touchdowns, both coming in the second half to receiver Preston Baugh, covering 18 and 5 yards.
Wise added 81 yards rushing on 23 carries, including a 1-yard TD run midway through the first quarter to put Northside up, 7-0.
Cabot tied the score late in the first quarter before the Grizzlies regained the lead, 10-7, on a 27-yard field goal from Henry Hernandez with 10:32 left until halftime. But it was Northside's last lead, as Cabot scored two touchdowns to take a 21-10 lead at halftime.
The Panthers later built a 28-16 advantage with more than six minutes left in the game before icing the win with an interception return for a touchdown nearly a minute later. Cabot came up with four interceptions on the night.


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HATTIESBURG, MS (WDAM) - For University of Southern Mississippi coach Jay Hopson, the final, regular-season football game at the University of Texas-El Paso is not just a means to an end, but an end in itself.
After pulling off a 21-20 victory Saturday against visiting Louisiana Tech University, the Golden Eagles (5-5, 4-3 Conference USA) are in position to at least have an opportunity to play in a fourth consecutive bowl game if they can take down the Miners (1-10, 1-6) at 2 p.m. Saturday at the Sun Bowl.
A win would give USM the minimum six victories necessary for postseason consideration, but Hopson said his only concern was the game in front of the Golden Eagles, not on a possibility that may or may not happen.
"We're never going to put the cart in front of the horse," Hopson said Monday during his final, regular-season news conference. "We've got to go to work … UTEP has our utmost respect, so we've got to get ready to play.
"Our guys are working hard. I think we're playing our best football right now. I really do, and we need that to continue."
The teams will be meeting for the 11th time, with USM holding a 6-4 series edge after winning the past three meetings.
The Golden Eagles are 3-2 in games played in El Paso, Texas, but USM has yet to pocket a road win this season.
An 1,126-mile road trip will not prevent the Golden Eagles from gathering as a team to celebrate Thanksgiving, Hopson said.
"We're going to be here, and we're going to have a team Thanksgiving dinner," Hopson said. "We'll celebrate that as a football team and that's always a fun deal."
Players of the Week for the Louisiana Tech game included:
Offense _ Sophomore receiver Quez Watkins, who had nine catches for 110 yards. It was Watkins' fourth 100-yard receiving game of the season and the fifth of his career.
Defense _ Junior defensive back Ernest Gunn, who stepped in when starter Rachuan Mitchell was injured. Gunn had three tackles (one solo) and a pass breakup.
Specials teams _ Sophomore place-kicker Briggs Bourgeois, who handled all place-kicking duties with senior Parker Shaunfield sidelined with a groin injury. Bourgeois hit all three of his extra-point attempts and forced touchbacks on four kickoffs.
Hopson said the Golden Eagles' 2019 signing class was shaping up.
The three-day early signing date is set to open Dec. 20.
"We feel really good," Hopson said. "We've got a lot of commitments and we have a great nucleus," Hopson said. "We're getting guys that fit our needs. I can't talk about anyone (specifically), so it's always tough when you start talking recruiting.
"But, we're very happy where we are."
Name Position, Ht., Wt., School/Hometown
- Dee Baker, RB, 6-0, 170, Northwest Rankin HS/Flowood
- Luke Baker, TE, 6-4, 198, Gulf Coast HS /Naples, FL
- Kendrick Brown, WR, 6-2, 195, Meridian HS/Meridian
- Jarrett Guest, ATH, 6-3, 172, Kennesaw Mountain HS/Acworth, GA
- Khalen Leonard, CB, 6-3, 175, Texas Prep Academy/Alvin, TX
- T.Q. Newsome, ATH, 6-1, 205, Gulfport HS/Gulfport
- Tahveon "Taz" Nicholson, ATH, 4-11, 179, Robert E. Lee HS/Jacksonville, FL
- Jadarrius Perkins, CB, 6-2, 175, Hattiesburg HS/Hattiesburg
- Matthew Ryals, OT, 6-7, 280, Purvis HS/Purvis
- Sam Saxton, QB, 6-5, 190, St. Michael's Academy/Austin, TX
- Chris Scruggs Jr., WR, 6-2, 175, Superior Collegiate Academy/Clearwater, FL
- Louis Smith, C, 6-3, 294, D 'Iberville HS/Biloxi
- Avery White, OLB, 6-4, 195, East Central HS/Kiln
- Jakryus Williams, WR, 5-10, 175, Saraland HS/Saraland, AL
- Corey Wilson, RB, 6-0, 175, Warren Central HS/Vicksburg
- Coker Wright, C, 6-4, 275, Brookhaven HS/Brookhaven
Source: Goldeneaglepride.com
Copyright 2018 WDAM. All rights reserved.


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Research Topics
Genomes and Genes
cystathionine beta synthase
Gene Symbol: cystathionine beta synthase
Description: cystathionine-beta-synthase
Alias: HIP4, cystathionine beta-synthase, beta-thionase, methylcysteine synthase, serine sulfhydrase
Species: human
Products: cystathionine beta synthase
Top Publications
Scientific Experts
More Information
- Boyles A, Billups A, Deak K, Siegel D, Mehltretter L, Slifer S, et al. Neural tube defects and folate pathway genes: family-based association tests of gene-gene and gene-environment interactions. Environ Health Perspect. 2006;114:1547-52 pubmed
- Golimbet V, Korovaitseva G, Abramova L, Kaleda V. The 844ins68 polymorphism of the cystathionine beta-synthase gene is associated with schizophrenia. Psychiatry Res. 2009;170:168-71 pubmed publisher..In conclusion, our study revealed a possible relation of the CBS 844ins68 polymorphism to schizophrenia. ..
- Shan X, Kruger W. Correction of disease-causing CBS mutations in yeast. Nat Genet. 1998;19:91-3 pubmed..These findings suggest a new drug target to treat homocystinuria and homocysteine-related vascular disease...
- Wang L, Chen X, Tang B, Hua X, Klein Szanto A, Kruger W. Expression of mutant human cystathionine beta-synthase rescues neonatal lethality but not homocystinuria in a mouse model. Hum Mol Genet. 2005;14:2201-8 pubmed..These transgenic animals should be useful in the study of homocysteine related human disease...
- Chen X, Jhee K, Kruger W. Production of the neuromodulator H2S by cystathionine beta-synthase via the condensation of cysteine and homocysteine. J Biol Chem. 2004;279:52082-6 pubmed..In addition, these studies provide a biochemical explanation for the previously inexplicable homocysteine-lowering effects of N-acetylcysteine treatments in humans. ..
- Frank N, Kent J, Meier M, Kraus J. Purification and characterization of the wild type and truncated human cystathionine beta-synthase enzymes expressed in E. coli. Arch Biochem Biophys. 2008;470:64-72 pubmed..The activity of the enzyme was unaffected by the redox status of the heme iron. Finally, we show that CBS is stimulated by S-adenosyl- l-methionine but not its analogs. ..
- Grossmann R, Schwender S, Geisen U, Schambeck C, Merati G, Walter U. CBS 844ins68, MTHFR TT677 and EPCR 4031ins23 genotypes in patients with deep-vein thrombosis. Thromb Res. 2002;107:13-5 pubmed..A putative protective effect of CBS 844ins68 should be further investigated. ..
- Singh L, Kruger W. Functional rescue of mutant human cystathionine beta-synthase by manipulation of Hsp26 and Hsp70 levels in Saccharomyces cerevisiae. J Biol Chem. 2009;284:4238-45 pubmed publisher..Based on these results we propose a novel model in which the ratio of Hsp70 and Hsp26 determines whether misfolded proteins will either be refolded or degraded...
- Pare G, Chasman D, Parker A, Zee R, Malarstig A, Seedorf U, et al. Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study. Circ Cardiovasc Genet. 2009;2:142-50 pubmed publisher..These associations offer new insight into the biochemical pathways involved in homocysteine metabolism and provide opportunities to better delineate the role of homocysteine in health and disease. ..
- Kopecká J, Krijt J, Raková K, Kozich V. Restoring assembly and activity of cystathionine β-synthase mutants by ligands and chemical chaperones. J Inherit Metab Dis. 2011;34:39-48 pubmed publisher..This study identified chaperone-responsive mutants that represent 56 of 713 known patient-derived CBS alleles and may serve as a basis for exploring pharmacological approaches aimed at correcting misfolding in homocystinuria. ..
- Kozich V, Kraus J. Screening for mutations by expressing patient cDNA segments in E. coli: homocystinuria due to cystathionine beta-synthase deficiency. Hum Mutat. 1992;1:113-23 pubmed..This bacterial expression system proved to be a rapid screening method for localizing pathogenic mutations in CBS, allowing us to sequence the affected portions of mutant cDNA within 7-10 days of harvesting cultured fibroblasts...
- Hnizda A, Spiwok V, Jurga V, Kozich V, Kodicek M, Kraus J. Cross-talk between the catalytic core and the regulatory domain in cystathionine ?-synthase: study by differential covalent labeling and computational modeling. Biochemistry. 2010;49:10526-34 pubmed publisher..Subtle differences at CBS surface indicate that enzyme activity is not regulated by conformational conversions but more likely by different allosteric mechanisms. ..
- Majtan T, Liu L, Carpenter J, Kraus J. Rescue of cystathionine beta-synthase (CBS) mutants with chemical chaperones: purification and characterization of eight CBS mutant enzymes. J Biol Chem. 2010;285:15866-73 pubmed publisher..This finding could have direct implications for the development of a therapeutical approach to pyridoxine unresponsive homocystinuria. ..
- Kraus J, Le K, Swaroop M, Ohura T, Tahara T, Rosenberg L, et al. Human cystathionine beta-synthase cDNA: sequence, alternative splicing and expression in cultured cells. Hum Mol Genet. 1993;2:1633-8 pubmed..Lastly, we demonstrate that expression of the human enzyme in CHO cells yields enzymatically active protein of the expected size with a half-life of approximately 14 hrs. ..
- Kery V, Bukovska G, Kraus J. Transsulfuration depends on heme in addition to pyridoxal 5'-phosphate. Cystathionine beta-synthase is a heme protein. J Biol Chem. 1994;269:25283-8 pubmed..These findings suggest that heme is functionally incorporated into CBS only during protein folding. This report describes the first instance of an enzyme that depends upon both heme and PLP for its function. ..
- Zhang G, Dai C. Gene polymorphisms of homocysteine metabolism-related enzymes in Chinese patients with occlusive coronary artery or cerebral vascular diseases. Thromb Res. 2001;104:187-95 pubmed..However, CBS 844ins68 may be a protective factor against vascular thromboembolic disease. The prevalence of CBS 844ins68 and MS A2756G in Chinese population is obviously lower than in Western Caucasian population. ..
- Münke M, Kraus J, Ohura T, Francke U. The gene for cystathionine beta-synthase (CBS) maps to the subtelomeric region on human chromosome 21q and to proximal mouse chromosome 17. Am J Hum Genet. 1988;42:550-9 pubmed..Mice partially trisomic for MMU 16 or MMU 17 should allow gene-specific dissection of the trisomy 21 phenotype. ..
- Kluijtmans L, Boers G, Stevens E, Renier W, Kraus J, Trijbels F, et al. Defective cystathionine beta-synthase regulation by S-adenosylmethionine in a partially pyridoxine responsive homocystinuria patient. J Clin Invest. 1996;98:285-9 pubmed..Furthermore, it indicates the importance of S-adenosylmethionine regulation of the transsulfuration pathway in homocysteine homeostasis in humans...
- Hu F, Gu Z, Kozich V, Kraus J, Ramesh V, Shih V. Molecular basis of cystathionine beta-synthase deficiency in pyridoxine responsive and nonresponsive homocystinuria. Hum Mol Genet. 1993;2:1857-60 pubmed..This missense mutation was detected in one allele of a pyridoxine nonresponsive patient and in both alleles of a pyridoxine responsive patient. The latter suggests that I278T is probably associated with pyridoxine responsiveness...
- Kraus J. Komrower Lecture. Molecular basis of phenotype expression in homocystinuria. J Inherit Metab Dis. 1994;17:383-90 pubmed..Using this method we identified the first 14 mutations in homocystinuria. The most common mutation in patients of predominantly 'Celtic' origin is the G919A transition which substitutes serine for glycine 307. ..
- Kruger W, Cox D. A yeast system for expression of human cystathionine beta-synthase: structural and functional conservation of the human and yeast genes. Proc Natl Acad Sci U S A. 1994;91:6614-8 pubmed..These results demonstrate the evolutionary conservation of CBS and establish the utility of a yeast expression system for studying human CBS. ..
- Singh L, Chen X, Kozich V, Kruger W. Chemical chaperone rescue of mutant human cystathionine beta-synthase. Mol Genet Metab. 2007;91:335-42 pubmed
- Kraus J, Oliveriusova J, Sokolova J, Kraus E, Vlcek C, de Franchis R, et al. The human cystathionine beta-synthase (CBS) gene: complete sequence, alternative splicing, and polymorphisms. Genomics. 1998;52:312-24 pubmed..Additionally, we report on a number of DNA sequence repeats that are polymorphic in North American and European Caucasians. ..
- Meier M, Janosik M, Kery V, Kraus J, Burkhard P. Structure of human cystathionine beta-synthase: a unique pyridoxal 5'-phosphate-dependent heme protein. EMBO J. 2001;20:3910-6 pubmed..This heme binding motif together with a spatially adjacent oxidoreductase active site motif could explain the regulation of its enzyme activity by redox changes. ..
- Linnebank M, Homberger A, Junker R, Nowak Goettl U, Harms E, Koch H. High prevalence of the I278T mutation of the human cystathionine beta-synthase detected by a novel screening application. Thromb Haemost. 2001;85:986-8 pubmed..800. Our data indicate that homocystinuria due to cystathionine beta-synthase deficiency is a frequently unrecognized disorder resulting in a high risk of thromboembolic events...
- Janosik M, Meier M, Kery V, Oliveriusova J, Burkhard P, Kraus J. Crystallization and preliminary X-ray diffraction analysis of the active core of human recombinant cystathionine beta-synthase: an enzyme involved in vascular disease. Acta Crystallogr D Biol Crystallogr. 2001;57:289-91 pubmed..The truncated CBS yielded crystals diffracting to 2.6 A which belong to space group P3(1) or P3(2). This is the first comprehensive structural investigation of a PLP and heme-containing enzyme. ..
- Taoka S, Lepore B, Kabil O, Ojha S, Ringe D, Banerjee R. Human cystathionine beta-synthase is a heme sensor protein. Evidence that the redox sensor is heme and not the vicinal cysteines in the CXXC motif seen in the crystal structure of the truncated enzyme. Biochemistry. 2002;41:10454-61 pubmed
- Sokolova J, Janosikova B, Terwilliger J, Freiberger T, Kraus J, Kozich V. Cystathionine beta-synthase deficiency in Central Europe: discrepancy between biochemical and molecular genetic screening for homocystinuric alleles. Hum Mutat. 2001;18:548-9 pubmed..In conclusion, homocystinuria in Central Europe may be sufficiently common to consider sensitive newborn screening programs for this disease...
- Aléssio A, Siqueira L, Bydlowski S, Hoehr N, Annichino Bizzacchi J. Polymorphisms in the CBS gene and homocysteine, folate and vitamin B12 levels: association with polymorphisms in the MTHFR and MTRR genes in Brazilian children. Am J Med Genet A. 2008;146A:2598-602 pubmed publisher..034). Since B(12) and folate were not different between these groups, a genetic interaction between diverse polymorphisms probably influences Hcy. Our results emphasize the role of genetic interactions in Hcy levels. ..
- Butler C, Knox A, Bowersox J, Forbes S, Patterson D. The production of transgenic mice expressing human cystathionine beta-synthase to study Down syndrome. Behav Genet. 2006;36:429-38 pubmed..They can also be used to develop therapies that target abnormalities in 1C-TS metabolism to improve cognition in persons with DS. ..
- Sebastio G, Sperandeo M, Panico M, de Franchis R, Kraus J, Andria G. The molecular basis of homocystinuria due to cystathionine beta-synthase deficiency in Italian families, and report of four novel mutations. Am J Hum Genet. 1995;56:1324-33 pubmed..Mutations A114V and I278T are carried by three and by seven independent alleles, respectively. The other four mutations--including G307S and A1224-2C, common among northern European patients--have not been detected...
- Kozich V, Sokolova J, Klatovská V, Krijt J, Janosik M, Jelínek K, et al. Cystathionine beta-synthase mutations: effect of mutation topology on folding and activity. Hum Mutat. 2010;31:809-19 pubmed publisher..In summary, our results show that topology of mutations predicts in part the behavior of mutant CBS, and that misfolding may be an important and frequent pathogenic mechanism in CBS deficiency. ..
- Dawson P, Cox A, Emmerson B, Dudman N, Kraus J, Gordon R. Characterisation of five missense mutations in the cystathionine beta-synthase gene from three patients with B6-nonresponsive homocystinuria. Eur J Hum Genet. 1997;5:15-21 pubmed..All of the mutant proteins exhibited decreased catalytic activity in vitro, which confirmed the association between the individual mutation and CBS dysfunction in each patient...
- Kim C, Gallagher P, Guttormsen A, Refsum H, Ueland P, Ose L, et al. Functional modeling of vitamin responsiveness in yeast: a common pyridoxine-responsive cystathionine beta-synthase mutation in homocystinuria. Hum Mol Genet. 1997;6:2213-21 pubmed..These studies show that the G797A mutation is an important cause of pyridoxine-responsive CBS deficiency and demonstrate the utility of yeast functional assays in the analysis of human mutations...
- Hnizda A, Majtan T, Liu L, Pey A, Carpenter J, Kodicek M, et al. Conformational properties of nine purified cystathionine β-synthase mutants. Biochemistry. 2012;51:4755-63 pubmed publisher..This study demonstrates that the proteolytic techniques are useful tools for the assessment of the biochemical penalty of missense mutations in CBS. ..
- Evande R, Blom H, Boers G, Banerjee R. Alleviation of intrasteric inhibition by the pathogenic activation domain mutation, D444N, in human cystathionine beta-synthase. Biochemistry. 2002;41:11832-7 pubmed..e., wild-type enzyme as isolated), "activated" (wild-type enzyme + AdoMet or the D444N mutant as isolated), and superactivated (D444N mutant + AdoMet or wild-type enzyme lacking the C-terminal regulatory domain). ..
- Giusti B, Saracini C, Bolli P, Magi A, Martinelli I, Peyvandi F, et al. Early-onset ischaemic stroke: analysis of 58 polymorphisms in 17 genes involved in methionine metabolism. Thromb Haemost. 2010;104:231-42 pubmed publisher..This study identifies significant genetic associations between premature ischaemic stroke and haplotypes in BHMT, CBS, FOLH1, MTR, PON2, TCN2 and TYMS genes involved in methionine metabolism. ..
- Marble M, Geraghty M, de Franchis R, Kraus J, Valle D. Characterization of a cystathionine beta-synthase allele with three mutations in cis in a patient with B6 nonresponsive homocystinuria. Hum Mol Genet. 1994;3:1883-6 pubmed..The apparently simultaneous appearance of more than one mutation in a single exon suggests they may have arisen by a gene conversion event or by nonhomologous recombination...
- Janosik M, Oliveriusova J, Janosikova B, Sokolova J, Kraus E, Kraus J, et al. Impaired heme binding and aggregation of mutant cystathionine beta-synthase subunits in homocystinuria. Am J Hum Genet. 2001;68:1506-13 pubmed..These data suggest that abnormal folding, impaired heme binding, and aggregation of mutant CBS polypeptides may be common pathogenic mechanisms in CBS deficiency...
- Gordon R, Cox A, Dawson P, Emmerson B, Kraus J, Dudman N. Mutational analysis of the cystathionine beta-synthase gene: a splicing mutation, two missense mutations and an insertion in patients with homocystinuria. Mutations in brief no. 120. Online. Hum Mutat. 1998;11:332 pubmed..Expression of recombinant CBS protein, containing the C165Y mutation, had no detectable catalytic activity. Each mutation was confirmed in genomic DNA...
- Ott N, Geddert H, Sarbia M. Polymorphisms in methionine synthase (A2756G) and cystathionine beta-synthase (844ins68) and susceptibility to carcinomas of the upper gastrointestinal tract. J Cancer Res Clin Oncol. 2008;134:405-10 pubmed..6%). The gene allele constellation I/I was not present. The current study suggests that there is no association between MTR A2756G polymorphism and the CBS (844ins68) insertion polymorphism and cancer of the upper gastrointestinal tract. ..
- Maclean K, Gaustadnes M, Oliveriusova J, Janosik M, Kraus E, Kozich V, et al. High homocysteine and thrombosis without connective tissue disorders are associated with a novel class of cystathionine beta-synthase (CBS) mutations. Hum Mutat. 2002;19:641-55 pubmed
- Song X, Zheng X, Zhu W, Huang L, Li Y. Relationship between polymorphism of cystathionine beta synthase gene and congenital heart disease in Chinese nuclear families. Biomed Environ Sci. 2006;19:452-6 pubmedTo study the relationship between polymorphism of cystathionine beta synthase (CBS) gene and development of congenital heart disease (CHD)...
- Kozich V, de Franchis R, Kraus J. Molecular defect in a patient with pyridoxine-responsive homocystinuria. Hum Mol Genet. 1993;2:815-6 pubmed
- Le Marchand L, Donlon T, Hankin J, Kolonel L, Wilkens L, Seifried A. B-vitamin intake, metabolic genes, and colorectal cancer risk (United States). Cancer Causes Control. 2002;13:239-48 pubmed..Our data also suggest that the relationships between CRC and the MTHFR A1298C and CBS 844ins68 polymorphisms warrant further study. ..
- Kruger W, Cox D. A yeast assay for functional detection of mutations in the human cystathionine beta-synthase gene. Hum Mol Genet. 1995;4:1155-61 pubmed..Our results also demonstrate that the yeast CBS assay can detect a large percentage of individuals heterozygous for mutations in CBS. This system should be useful in determining the relationship between CBS mutations and human disease...
- de Franchis R, Kraus E, Kozich V, Sebastio G, Kraus J. Four novel mutations in the cystathionine beta-synthase gene: effect of a second linked mutation on the severity of the homocystinuric phenotype. Hum Mutat. 1999;13:453-7 pubmed..In this context, a search for additional mutations in cis may sometimes be necessary to establish a good genotype-phenotype relationship...
- Kraus J, Janosik M, Kozich V, Mandell R, Shih V, Sperandeo M, et al. Cystathionine beta-synthase mutations in homocystinuria. Hum Mutat. 1999;13:362-75 pubmed..Mutations due to deaminations of methylcytosines represent 53% of all point substitutions in the coding region of the CBS gene...
- Li Y, Cheng J, Zhu W, Dao J, Yan L, Li M, et al. [Study of serum Hcy and polymorphisms of Hcy metabolic enzymes in 192 families affected by congenital heart disease]. Beijing Da Xue Xue Bao Yi Xue Ban. 2005;37:75-80 pubmed..68 bp insertion at exon 8 of CBS gene base 844 could be a risk factor for CHD, and the insertion in parents (especially in mothers) could increase CHD risk in offspring. ..
- Griffioen P, de Jonge R, van Zelst B, Montserrate Brouns R, Lindemans J. Detection and allele-frequencies of the 833T>C, 844ins68 and a novel mutation in the cystathionine beta-synthase gene. Clin Chim Acta. 2005;354:191-4 pubmedThe most common 833T>C/844ins68 in cis double mutation in the cystathionine beta synthase (CBS) gene probably is non-pathogenic because the 68-bp insertion eliminates the 833T>C mutation due to alternative splicing...
- Singh L, Gupta S, Honig N, Kraus J, Kruger W. Activation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70. PLoS Genet. 2010;6:e1000807 pubmed publisher..These findings suggest that proteasome inhibitors and other Hsp70 inducing agents may be useful in the treatment of a variety of genetic diseases caused by missense mutations. ..
- Ichinohe A, Kanaumi T, Takashima S, Enokido Y, Nagai Y, Kimura H. Cystathionine beta-synthase is enriched in the brains of Down's patients. Biochem Biophys Res Commun. 2005;338:1547-50 pubmed..The over-expression of CBS may cause the developmental abnormality in cognition in DS children and that may lead to AD in DS adults. ..
- Carballal S, Cuevasanta E, Marmisolle I, Kabil O, Gherasim C, Ballou D, et al. Kinetics of reversible reductive carbonylation of heme in human cystathionine ?-synthase. Biochemistry. 2013;52:4553-62 pubmed publisher..Reversible reduction of CBS by a physiologically relevant oxidoreductase is consistent with a regulatory role for the heme and could constitute a mechanism for cross talk among the CO, H2S, and superoxide signaling pathways. ..
- Janosik M, Sokolova J, Janosíková B, Krijt J, Klatovská V, Kozich V. Birth prevalence of homocystinuria in Central Europe: frequency and pathogenicity of mutation c.1105C>T (p.R369C) in the cystathionine beta-synthase gene. J Pediatr. 2009;154:431-7 pubmed publisher..To estimate the frequency of the cystathionine beta-synthase deficiency caused by c.1105C>T mutation in Central Europe compared to Norway, and to examine the pathogenicity of the corresponding p.R369C mutant enzyme...
- Sen S, Banerjee R. A pathogenic linked mutation in the catalytic core of human cystathionine beta-synthase disrupts allosteric regulation and allows kinetic characterization of a full-length dimer. Biochemistry. 2007;46:4110-6 pubmed..Furthermore, analysis of individual single mutations has permitted, for the first time, partial kinetic characterization of a full-length dimeric form of human cystathionine beta-synthase. ..
- Kraus J, Packman S, Fowler B, Rosenberg L. Purification and properties of cystathionine beta-synthase from human liver. Evidence for identical subunits. J Biol Chem. 1978;253:6523-8 pubmed..It is possesses serine sulfhydrase as well as cystathionine synthase activity. It has a broad pH optimum from 8.4 to 9...
- Ereño Orbea J, Majtan T, Oyenarte I, Kraus J, Martinez Cruz L. Structural insight into the molecular mechanism of allosteric activation of human cystathionine β-synthase by S-adenosylmethionine. Proc Natl Acad Sci U S A. 2014;111:E3845-52 pubmed publisher..The structure described herein paves the way for the rational design of compounds modulating hCBS activity and thus transsulfuration, redox status, and H2S biogenesis. ..
- Kim J, Hong S, Park J, Park S, Kim S, Cho E, et al. Expression of cystathionine beta-synthase is downregulated in hepatocellular carcinoma and associated with poor prognosis. Oncol Rep. 2009;21:1449-54 pubmed..0042) after considering tumor stage and tumor size. Thus, the expression level of CBS mRNA could be useful to predict clinical outcome of HCC, especially for patients with low AFP levels. ..
- Frank N, Kery V, Maclean K, Kraus J. Solvent-accessible cysteines in human cystathionine beta-synthase: crucial role of cysteine 431 in S-adenosyl-L-methionine binding. Biochemistry. 2006;45:11021-9 pubmed
- Oliveriusova J, Kery V, Maclean K, Kraus J. Deletion mutagenesis of human cystathionine beta-synthase. Impact on activity, oligomeric status, and S-adenosylmethionine regulation. J Biol Chem. 2002;277:48386-94 pubmed
- Botto L, Yang Q. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. Am J Epidemiol. 2000;151:862-77 pubmed..Studies of the C677T allele in relation to oral clefts, Down syndrome, and fetal anticonvulsant syndrome either have yielded conflicting results or have not been yet replicated. ..


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Kline one-hits conference foe Marked Tree in 11-1 win
(High School Sports ~ 04/19/18)
Kern Kline only allowed one hit as his Warrior teammates gave him plenty of run support in an 11-1 win over Marked Tree at home this past Thursday. Eli McCrary led off with a walk for Marked Tree in the top of the first inning as Aaron Hutchens popped out and Kentarius Allen struck out. ...
Hartley selected to Class 1A all-state team
(High School Sports ~ 04/19/18)
Bay's Mallory Hartley, who helped lead the Lady Yellowjackets to a 31-7 record this past season advancing to the quarter-finals of the Class 1A state tournament, was selected to the Class 1A all-state basketball team. Hartley led Bay in scoring with 18 points a game while pulling down nine rebounds a contest while getting two steals a game. ...
Lady Wildcats JV fall at home to Wynne
(High School Sports ~ 04/19/18)
The Lady Wildcats JV fell behind early and could never catch back up as the Wynne JV took a 10-6 win this past Monday in softball action in Trumann. The Lady Yellowjackets used a hit, stolen base and passed ball to get on the board taking an early 1-0 lead after the top of the first inning. ...
Area sports roundup
(High School Sports ~ 04/19/18)
The Lady Hornets picked up two wins as they defeated Pocahontas 11-0 this past Monday and Marked Tree 16-1 this past Tuesday. Against Pocahontas, Anna Walker had four hits, four RBIs and a run scored to lead the Lady Hornets at the plate. Jehlian Wright had two hits and scored three runs as Jayden Roark had a hit, two RBIs and a run scored. ...
Big inning sends Lady Warriors to win over Bay
(High School Sports ~ 04/19/18)
EPC scored 13 runs in the top of the fourth inning to blow open a close game for a 16-0 win over the Lady Yellowjackets in high school softball action this past Tuesday in Bay. Keragan Gordon grounded out leading off for EPC as Meagan Allen struck out. ...
Terrell found guilty of murder
(Local News ~ 04/19/18)
Christopher Terrell, 51, of Marked Tree, was found guilty of first degree murder last week and sentenced to 23 years in prison after a jury deliberated for over two hours on the third day of the trial. Terrell was arrested in 2014 along with Betty Grant, also of Marked Tree, in connection with the death of James Hunt, 49, of Tyronza, on Nov. ...
Stories from Thursday, April 19, 2018
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Word of Encouragement: "Words"
Jan 06, 2015 06:24AM
By Stephen York
Jan 06
More of God's Encouragement
May the words of my mouth
and the meditation of my heart
be pleasing in Your sight,
my Rock and my Redeemer.
Psalm 19:14 NIV
For sure Lord !!! FOR SURE !!!!
As always, Remember to have a God day !!
Love in Christ.
Follow us on Facebook at https://www.facebook.com/yourtewksburytoday/ Follow us on Twitter at @TewksburyToday Follow us on Instagram at YourTewksburyToday


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HOUSTON (KTRK) -- Investigators released a composite sketch of one of the suspects who murdered a Brinks armored car guard last month.
The FBI and Houston Police are hoping the public can help them identify the killer who they say "ambushed and executed" Brinks guard Alvin Kinney in front of a Galleria area bank in the 5700 block of Westheimer on February 12.
A Brinks armored guard team was making a delivery at Capital One bank when at least three armed assailants wearing body armor and face-shield masks approached Kinney and opened fire.
A second Brinks guard returned fire as the assailants backed up a stolen truck and stole several bags of cash.
A reward of $100,000 has been offered for information leading to the arrest and identification of the masked gunmen.
Anyone with information is asked to call 1-800-CALL-FBI or Crime Stoppers at 713-222-TIPS.
Suspect sketch released in Brinks guard murder
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Bring the influence of Colorado and Maine right onto your tabletops, with a spectacular Rolf Icy Pinecone 42 oz Glass Carafe. Perfectly etched with an impeccably frosted pinecone design and a multi faceted detail, this Carafe is a statement of sophistication and elegance combined. Its great contrast to its finely cut and polished pine needles which sparkle in the sunlight, will give your table setting a crisp look.
- Height: 10.125 inches
- Width: 5.5 inches
- Capacity: 42 oz
American glass manufacturer Rolf Glass creates imaginative designs and glass tabletop giftware engraved with distinctive images of flora and fauna. Tireless leaders in high-quality cut glass and engraved giftware, the Rolf Glass name is recognized worldwide for characteristic attention to detail and charming patterns. This collection presents the best, most unique pieces inspired by nature and the wildlife around us.
Headquartered in a former Lenox Crystal factory in Mount Pleasant, Pennsylvania, where glassmaking has a long and storied history, Rolf Glass has demonstrated its commitment to not only American manufacturing but exceptional quality and fast availability of product


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Hario V60 02 Ceramic Coffee Dripper White
Hario is known for making quality glassware and excellent coffee accessories like the Hario V60 02 Ceramic Coffee Dripper. Here are some of the features of this product.
- The V60 name comes from the design of dripper. The V is derived from the cone shape of the dripper which looks like a letter V which has a 60 degree angle.
- This dripper has a single large hole that lets you determine the flavor of the coffee that you will be making because it allows you to control the water flow.
- The Hario V60 02 Ceramic Coffee Dripper comes with spiral ribs that helps to get the most out of the coffee expansion by enabling air to pass through in order to escape.
- It is bigger than most drippers in the market. That bigger size is one reason why it is preferred by many baristas and cafes.
- The ceramic body of this dripper is made with the same high standards that have made the Hario name a favorite among coffee lovers.
- It comes with a free measuring spoon that perfectly matches the dripper.
- This dripper can brew up to six cups of coffee depending on the size that you are using.
- It has excellent heat retention which allows you to enjoy your coffee for a longer period.
- Because of the high quality ceramic body used in the Hario V60 02 Ceramic Coffee Dripper, cleaning is a lot easier as compared with other similar products.
- It comes with a free measuring spoon.
- The V60 02 Ceramic Coffee Dripper provides more extraction than other filters.
This beautiful product is going to enhance your collection of coffee accessories, but it's not just for decoration, because it also scores well when it comes to functionality.


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Bat #1: Victus V-Cut Hard Maple Wood Baseball Bat: VMR Black Gloss
Bat #2: Rawlings BIG STICK Birch Wood Baseball Bat: PAI13B
Most Popular Items
Lizard Skins 1.1 mm Bat Grips
$10.99 – $15.99
JustBats Batting Gloves
JustBats Batter's Box
Bat #1: Victus V-Cut Hard Maple Wood Baseball Bat: VMR Black Gloss
Bat #2: Rawlings BIG STICK Birch Wood Baseball Bat: PAI13B
Free Shipping!
Approximate -3 Length To Weight Ratio
Colorway: Black | Red
Knob Shape Can Vary, But Will Most Likely Feature A Slight Flare
V-Cut Bats Will Vary In Their Turn Model | Barrel Diameter Can Change From Bat-To-Bat
This V-Cut Will Feature A More Balanced Feel
Bone Rubbed For A More Compressed Barrel
Cut From Quality Maple Wood
Should Feature A Cupped Barrel End
Pro Ink Dot Certified For MLB Approval
Victus wanted to change the game. So, they went all in on a dream and started handcrafting wood bats in a friend's garage. Their commitment to baseball players created a higher standard in the wood bat industry. Big Leaguers and professional players trust Victus because they feel their obsession with quality, attention to detail, and taste for useful innovation in every swing.
Victus has solidified themselves as one of the premier wood bat manufacturers in the Big Leagues. Their obsessive attention to detail, high-quality wood, and iconic logo can be seen on national television almost every time you watch an MLB game. Their all-new Victus Gloss V-Cut was destined for the pros with the same quality wood and hard finish, but a non-structural imperfection got them cut from the Pro line. V-Cuts are designed for players not worried about turn models or bat color, but love mash and rake! V-Cuts are not model-specific. Their nob, handle, barrel size and balance point are not specific prior to manufacturing, so they can be any model in the Victus lineup or a combination of multiple turn models. Change Your Game. Swing Victus.
This Victus V-Cut Hard Maple Wood Baseball Bat (VMR Black Gloss) features an approximate drop 3 length to weight ratio, a large, but shorter barrel, and will vary from a balanced to slightly end-loaded swing weight. This V-Cut comes bone rubbed which means it features a more compressed barrel and is recommended for those heavy hitters out there. Typically, V-Cut models will feature a thicker handle and a larger knob but this will vary from bat to bat. Buck tradition and purchase one of these Victus wood bats today with free shipping right here at JustBats.com. Never forget, we're here from click to hit!
Reviews (7)
Questions and Answers (17)
Have a question about the Victus V-Cut Hard Maple Wood Baseball Bat: VMR Black Gloss? Ask our team of experts and they will respond within 24 hours.
About the Brand
Victus Sports was founded based on the experience of bat makers Jared Smith and Ryan Engroff and the long term experience and business acumen of Gregg Balin. Through extensive trial and error, Victus has finally perfected their art. In the past year Victus has been vaulted into the national spotlight as one of the hottest new bat makers on the planet.
This popularity comes as a result of their pledge to use ONLY pro quality, Number One Prime Wood. Many wood bat companies lead players to believe that they're getting Number One Prime Wood, when in most cases they are not. Using the best quality wood available will not only add longevity to the life of a bat, it can also add 15+ feet of distance to a hit.
Major League Approved, and used by numerous MLB All Stars, Victus is considered one of the most creative and innovative wood bat companies in the world. With their unique color finishes and logo designs, Victus thrives on setting themselves apart from the competition. Once you've used a Victus bat, you'll never want to swing any other wood bat again!
Bat Properties
|Baseball Bats
|Wood Baseball
|Bat Type
|Personalization Eligible Bundle and Save
|Ink Dot
|$100 - $199.99
|Swing Weight
|Wood Type
Free Shipping!
2 1/2 Inch Barrel Diameter
Approximate -2 to -3 Length to Weight Ratio
Slightly End-Loaded (Slightly Barrel Heavy) Bat
Colorway: Black | Natural
Constructed Of Birch Wood
I13 Turn Model: Thin Handle, Medium Taper and Thick Barrel
29/32 Inch Handle Diameter
Conventional Knob (Some May Find Slightly Flared)
Cupped Barrel End
Exclusive to JustBats! The PAI13B Adult wood baseball bat exemplifies excellence and durability. Rawlings wood bats have defined the careers of numerous baseball greats over the years and continue to represent Rawlings' core value - quality and innovation. This modernized design offers breakthrough technologies and progressive materials that unite to drive performance while increasing one's batting average. It all starts with the VELO barrel design which maximizes swing speed and control for the ultimate experience during every at bat. VELO baseball bats are built for players looking for a fast balanced stick. The Birch construction offers an extremely dense wood for a much harder hitting surface and stiffer flex in comparison to other woods. This allows energy to transfer efficiently to the baseball for further ball fight in each hit. With a 110 turning model and a balanced swing weight, the PAI13B is typically preferred by a power hitter. Rawlings wood baseball bats remain the authentic, established choice for those seeking to significantly enhance their offense. Rawlings: The Finest in the Field!
This Rawlings VELO Birch Wood Baseball Bat: PAI13B Adult features a 2 1/2 inch barrel diameter, a one inch handle, and an approximate -3 length to weight ratio. This is the perfect choice to help ease the transition from a BBCOR model. Pick up yours today with fast, free shipping from JustBats.com. We're here from Click to Hit!
Reviews (12)
Questions and Answers (10)
Have a question about the Rawlings BIG STICK Birch Wood Baseball Bat: PAI13B? Ask our team of experts and they will respond within 24 hours.
About the Brand
Rawlings is a major manufacturer of competitive team sports equipment and apparel for baseball, basketball, and football, as well as licensed MLB, NFL, and NCAA retail products. Rawlings is a major supplier to professional, collegiate, interscholastic and amateur organizations worldwide, including the Official Baseball Supplier to Major League Baseball.
The first real innovation in glove making occurred in 1912 when Rawlings Sporting Goods Company introduced the "Sure Catch" glove, which was "endorsed by leading players all over the country." The Sure Catch was a one-piece glove with sewn-in finger channels and looked better suited for a duck's foot than a man's hand. Catchers' mitts used at the time were large and bulky with a single leather thong passing for a web.
In 1920, Bill Doak, a journeyman pitcher for the St. Louis Cardinals, approached Rawlings with an idea for improving the baseball glove from a mere protective device to a genuine aid in fielding. The "Bill Doak" model was so revolutionary that it stayed in Rawlings' line until 1953. Its key feature was a multi-thong web laced into the first finger and thumb, which created for the first time in baseball's young life, a natural pocket.
In 1925, Rawlings unveiled a three-fingered fielder's glove, and ten years later improved the Bill Doak model with a two-piece leather web. At the same time, the "T" web became a rage for first basemen's mitts. The pocket underwent a pronounced change in 1941 when the Trapper Mitt, also known as the Claw, appeared. The "Deep Well" pocket was so unique that Rawlings quickly patented it. The design was improved in 1950 by adding a leather piece across the top. Another significant creation occurred in 1948 with the three-fingered Playmaker. A five-fingered fielder's model, with all fingers laced together, provided greater pocket control.
The six-fingered Trap-Eze evolved in the 1960's. In more recent years, Rawlings produced the Fastback design, which gives a glove a snugger fit, greater extension, and overall control. The Holdster is a slot through which a finger can be extended for additional protection from impacts on the pocket. Then, there is the Edge-U-Cated Heel with its extended U-shaped lacing and the Pro H Web and much-copied Basket Web.
Some of Rawlings more recent glove innovations also include the unique Spin-Stopper design which reduces ball spin when the ball hits the glove, and the Cantilever glove design feature that provides a cushioned area between the hand and the glove's palm area. In all, Rawlings has produced and patented more functionally innovative glove features and designs than that of any other glove manufacturer. The result is that the modern baseball glove is much larger, more comfortable, better padded and made to last far longer than its ancestors. It is not uncommon to see today's Major League players wearing the same Rawlings' glove they wore during their college playing days. In fact, Rawlings is the #1 glove in the major leagues. Rawlings maintains about 65 models of baseball and softball mitts and gloves in its line. The prototypes of virtually all of them have been field tested by professionals before entering a sporting goods dealer's inventory.
Bat Properties
|Barrel Diameter
|2 1/2"
|Baseball Bats
|Wood Baseball
|Bat Type
|Black Natural
|Closeout Bats Personalization Eligible Deal Of The Day Bundle and Save Exclusive Bats Used
|End Design
|Hitting Style
|Power Hitter
|Ink Dot
|$0 - $99.99
|Swing Weight
|Slightly End-Loaded
|Wood Type
Need Help Finding a Bat?
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Afterschool activities to resume for Hawaii Island on Sept. 11, schools statewide to remain open except Hana High & Elementary
Due to the latest forecast of Tropical Storm Olivia, the Hawaii State Department of Education (HIDOE) will resume afterschool activities on Hawaii Island tomorrow, Sept. 11. In Maui County, all afterschool activities will remain canceled for tomorrow and Hana High & Elementary will be closed.
All other schools statewide will be open tomorrow.
If Maui County officials activate evacuation shelters at Maui County campuses, those schools will need to be closed to allow emergency management agencies to stand up shelters. Please check Maui County's website for shelter information.
As the situation evolves, HIDOE will continue to provide updates about cancellations and closures on ourwebsite and social media —Twitter and Facebook. If you have further questions about whether or not your school or office will be open, please contact your principal or supervisor.
Olivia continues to make its way west at a rate of 10 mph. A continued west to west-southwest motion is expected over the next few days. On the forecast track, Olivia will be moving over the main Hawaiian Islands late Tuesday night into Wednesday. Gradual weakening is forecast over the next 48 hours, but Olivia is expected to remain a powerful Tropical Storm as it moves across the islands and could bring damaging wind, rains, flooding and surf.


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Choose a company in the area of Alabama has never been so easy.
Our matchtmaking system between homeowners and contractors, independant from any organisation, is made to put in competition specialized companies close to you.
You have the opportunity to formulate today a contact form for qualified pros in Mobile.
We know how time consuming it can be to find a qualified contractor. That is why we've created 3 simple steps to finding an experienced project specialist.


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You can't just assume that without technology you can manage to make it in this vast growing world because of it. You need to invest in improving your technology no matter where you are working or the industry you are working in. one of the sector that is growing massively and fast is the area of real estate investment. You need to not that investor out there of real estate are doing all they can to feature online in advertising the properties they have. If you fail also to take advantage of the dispensation of the techy, you will finally close your business because there is no one who is ready to be behind. Doing things technologically should not be overwhelming now that a lot of people can access the internet and having smartphones is no longer a problem in this generation. Visit https://ibuildapp.com/marketplace/Solutions-Real-Estate/?all=1 to learn more about Property Management.
As a real estate professional, it is advisable to make sure you install the real estate app on your phone if you are loyal to your business. It is an important thing to have it because of several things that you should be aware of. From renters to real estate agents to homeowners, it is vital to have a real estate app installed in the mobile phones. This article aims at summarizing some of the important reasons why you should install a real estate app on your smartphone.
One of the very first benefits that you are going to gain as a real estate agent when you invest in installing the real estate app in your phone is that there is going to be a faster property search. For more info on Property Management, click here. Everything that the renters want to know about the properties may it be the place, price, area, images of the house, name them will be seen through the real estate app. The ability to give these quick and easy searches will inevitably enhance your customer experience and also help you to maintain and attract the possible customers.
Another thing is that it helps you to have improved customer support and communication. You need to have a healthy communication with your clients as a real estate agent. Through the app on your phone, you will be able to have a direct contact with both new, old and potential customers.
You will also have an increased speed of the sales process. Through the improvement of communication through the app, it is possible to complete the selling process of the properties that you have.


text: Below you will find a demonstration of the Large Chamber testing process, performed at the NTA Test Lab, where our turnaround time is just eight days. This test method is a way to quantify how much newly manufactured panel products contribute to indoor air quality, and can be used to determine compliance with formaldehyde emission limit requirements for many regulatory agencies, such as HUD and CARB. You can learn more about Formaldehyde, the ASTM E1333 standard and our Formaldehyde Testing Services here, or simply contact us.


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Tips for History Colorado Center
History Colorado Center Tips
The weather was snowy . I wore something a bit formal however people in the auditorium were dressed up and casual. This was my first even and didn't know how to dress for this occasion. I would still dress up a bit for a lecture with a Jass Band. ;) .
Five Points: The Cradle of Jazz in the Rockies
It's light snack food so either plan to leave & eat or eat before coming in & drinks are reasonably priced, they take cash & credit cards.
Event starts at 6pm and street parking is free after 6pm so it is definitely cheaper to park on the street than in their garage.


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This post is over 30 days old. The position may no longer be available
UI/UX designers
Posted by Shiromi (@shiromi)
Divum Corporate Services Pvt Ltd https://hasjob.co/divum.in/4ka9u , Bangalore · www.divum.in · Full-time employmentFull-time employment · Graphic DesignGraphic Design
Looking for passionate UI/UX designers with ability to work in a high pressure environment.
Expertise required in UI/UX design tools including Adobe Photoshop, Illustrator, Sketch etc.
You will be involved in wire framing, developing UI/UX designs for web and mobile platforms.
Looking at proficiency in developing simple, clean, elegant user experience.
Relevant experience of 3 - 4 years required.
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It is NOT OK for recruiters, HR consultants, and other intermediaries to contact this employer


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Petite Sienna earrings – Rainbow
Out of stock
Get an Email when this product is back in stock
A dainty version of our daring Sienna, the Petite Sienna is still a prism of flirty finesse that communicates confidence and splendour. Set in gold in tiers of three, Vintage Rose, Misty Pink & Chartreuse crystals dance together in flawless synchronisation surrounded by smaller stones of the same colors. Combine with other pieces from our Sienna collection to complete your look.
Length: 2.8 cm
Crystals: Swarovski
Color: Gold, Material: Brass
Art no. 61645


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artists: EPIA / Broads
title: Local Closures
format: limited edition CD
keywords: electronic experimental norwich drone folk lo-fi Norwich
EPIA starts the split with 'Many Less Ears'. Not sure how many ears EPIA had before the split but I hope it was more then 4 so a few less wouldn't stop the music production that EPIA is so good at. Cause hearing this music is quite the perfection. Going for real atmospheric material that is played out with seemingly real live played instruments in combo with electronics. The beginning might sound like it would be a shimmering emotional piece, but as soon as a energetic upbeat-beat and a wobbly baseline joins in the flames of quality are lid like a cozy fire that runs behind you forcing your feet to run around the flames. I could think of worse things to do & be entertained by!
Then 'Leaves Return' (also by EPIA) comes in which features interesting music in which stretchy synthesizers stretch themselves out (with a little help!) and soft words are spoken like a gentle whisper of dreams. There are pretty piano notes played too, turning the track into a sweetly flavored early evening or early morning kind of track. It's nice enough to continue dreaming, or indeed lay down and start a new one with this music as the soundtrack.
British Columbia, 1981 is another lovely piece of music by EPIA. It has this lovely opening-up flow that reminded me of the magic that the Icelandic band Mûm is known to sprinkle over their music. But where the fairytale like dream music by the Icelandic friends sounds more princess like, this is more material that for some reason would be great to imagine a singing prince on a horse by. It's romantic, soothing, yet strong in an handsome kind of dreaming way. Is EPIA the prince or princess on the horse of your secret dreams, or indeed just a magical music maker?
Random Awkward Movement is EPIA bringing the finest piano keys to life, playing them like an emotional connected human that has the power to translate love through mellow melodies. But don't think this is all magic and slow motion sentimental wonderful material as EPIA brings in a square pusher-like beat to satisfy the so called intelligent electronic fans.
Last track by EPIA is 'Other Outs' which is pretty pleasant, very warm, cozy, crispy material that has sunshine written all over it. It is for the most part very atmospheric but a little but over the half of the material it shifts into a bright uptempo rocker that seems to be a uplifting reach for us to fly towards the blue sky.
And then it is time for the split to pass over to the artist we all had been waiting for 'Broads'. Broads it's first track is 'Norfolk Mountain Explorers' which sounds so well mixed that it almost inflicts orgasms when listened through headphones. The sound is so nice and round, in full stereo it seems; a very friendly atmospheric opener in which a slow stepping beat, a light melody and a ambient setting of prettiness is simply there to please anyone who comes across it.
Then Broads continues with a super rad work named 'Carriage Return' which you simply might become enthusiastic about when hearing it. It has all the goodness of the previous track but here it's a nice rolling beat, a super smooth loving bass and warm organ melody to please the ears. It's a real rocker that functions in a subdued way; it sounds very loving and human while at the same time being pretty tight! The track is solid for sure!
Broads's 'Teal' is showcasing a completely different side with Broads singing wonderfully in a gentle way and guitar sweetness on a slick sounding beat. I imagine Broads performing this song for lovers in the early sunday morning enjoying breakfast in bed and a sweet performance of intimate good loving music. What can a person want more other than it never to end?
Broads then comes with 'Misc Tea' which feels a bit like a little intermezzo. It's very minimal, sweet, pleasant; like a teaspoon of sugar and some milk in a fine cup of tea.
Watch-Wearing ~ I've Been Invited To A Heavy Wedding is a very nice example of a super well progressive track in which sweetness and friendliness in kind music slowly transforms itself into a warm noisy experiment that feels like we are looking at airplanes flying over our heads in full speed, probably full of people heading towards sunny destinations. It's okay as this split by Broads and EPIA is sunny enough to bring the good weather and warmth straight to wherever you are tuned in from. This pretty release can be bought at the following link:


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Paxton is a chic and fun handwritten font that is absolutely perfect for quotes, products, logos, packaging, and so much more!
Fresh and clean
What you get?
Format: OTF, TTF and WOFF
If you need help, just write me!
Nursery Art :)
Introducing Design School – our jam packed platform with its own mini search engine! Design School was made to help you learn all there is to know about fonts, graphics, templates, designs, file types, different software programs, Frequently Asked Questions and much much more.


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Posted by: plainab« on: March 23, 2012, 11:36:02 PM »
An option 3 is to distribute two flavors (SoA, ToB) of all-in-one zip files containing both the installation manager and the required package.this is best for 90% of the people who will use this. I know I've helped a few people who were struggling with the install location and even how to start using it.
but you lose the modularity that I am taking advantage of in this post (manager changed, packages did not).doesn't have to be that way. you can still keep them separate, not with the main download but made available for testing purposes should you need to make an update to any of the parts.
This way you get the benefit of (in the public's eye) stable releases as whole install packages and beta/testing releases as individual parts.


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Come join us in Oakland for some Hip-Hop Heaven on Labor Day. A full day of great music and special guests. We will be handing out Natural Cannabis Merchandise.
HIERO DAY is a one day event, combining an outdoor festival, concert, food, and block party where thousands come to celebrate all that is good about Oakland.


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A choice of eight of the most beautiful and famous songs by Ludovico Einaudi, arranged for Guitar by John Bailo, with transcriptions in standard notation and tablature.
Here are the titles: Beautiful Night, Odd Days, The Two Rivers, Julia, Waves, Nefeli, Password, Morning Star.
A CD is included, containing the execution (by John Bailo) of the eight tracks plus a bonus track with a performance of 'The Waves' in version 12-string Guitar.