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Ichthyosis Vulgaris (VI)
Categories: Genetic diseases, Rare diseases, Skin diseases
Aliases & Classifications for Ichthyosis Vulgaris
MalaCards integrated aliases for Ichthyosis Vulgaris:
autosomal dominant
ichthyosis vulgaris:
Inheritance autosomal dominant inheritance
MalaCards categories:
Global: Genetic diseases Rare diseases
Anatomical: Skin diseases
Summaries for Ichthyosis Vulgaris
NIH Rare Diseases : 52 Ichthyosis vulgaris is a common skin disorder passed down through families that leads to dry, scaly skin. It often begins in early childhood. Treatment may include heavy duty moisturizers which contain chemicals that help the skin to shed normally, including lactic acid , salicylic acid, and urea. Ichthyosis vulgaris can be a nuisance, but it rarely affects overall health. The condition usually disappears during adulthood, but may return in later years. This condition is inherited in an autosomal dominant pattern.
MalaCards based summary : Ichthyosis Vulgaris, also known as ichthyosis simplex, is related to ichthyosis, congenital, autosomal recessive 2 and ichthyosis, congenital, autosomal recessive 4a, and has symptoms including trichorrhexis invaginata An important gene associated with Ichthyosis Vulgaris is FLG (Filaggrin), and among its related pathways/superpathways are Developmental Biology and Keratinization. The drugs Protective Agents and Monolaurin have been mentioned in the context of this disorder. Affiliated tissues include skin, heart and bone, and related phenotypes are asthma and eczematoid dermatitis
Disease Ontology : 12 An ichthyosis that has material basis in heterozygous mutation in the filaggrin gene on chromosome 1q21 and is characterized by dead skin cells accumulate in thick, dry scales on your skin's surface.
OMIM : 56 The phenotypic characteristics of ichthyosis vulgaris include palmar hyperlinearity, keratosis pilaris, and a fine scale that is most prominent over the lower abdomen, arms, and legs. Marked presentation includes prominent scaling, whereas mild presentation consists of palmar hyperlinearity, keratosis pilaris, and, in some cases, fine scaling (summary by Smith et al., 2006). (146700)
KEGG : 36 Ichthyosis vulgaris is one of the most common genetic keratinization disorder characterized by follicular keratosis and grey scaling on the flexor limbs. It is caused by defective synthesis of filaggrin that leads to reduction of keratohyalin granules in epidermis. The condition is inherited in an autosomal dominant pattern.
UniProtKB/Swiss-Prot : 73 Ichthyosis vulgaris: The most common form of ichthyosis inherited as an autosomal dominant trait. It is characterized by palmar hyperlinearity, keratosis pilaris and a fine scale that is most prominent over the lower abdomen, arms, and legs. Ichthyosis vulgaris is characterized histologically by absent or reduced keratohyalin granules in the epidermis and mild hyperkeratosis. The disease can be associated with frequent asthma, eczema or hay fever.
Wikipedia : 74 Ichthyosis vulgaris (also known as "Autosomal dominant ichthyosis," and "Ichthyosis simplex") is a skin... more...
Related Diseases for Ichthyosis Vulgaris
Symptoms & Phenotypes for Ichthyosis Vulgaris
Human phenotypes related to Ichthyosis Vulgaris:31
Symptoms via clinical synopsis from OMIM:56
Clinical features from OMIM:146700
UMLS symptoms related to Ichthyosis Vulgaris:
trichorrhexis invaginata
Drugs & Therapeutics for Ichthyosis Vulgaris
Drugs for Ichthyosis Vulgaris (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):(show all 13)
Interventional clinical trials:(show all 15)
Inferred drug relations via UMLS 71 / NDF-RT 50 :
Cochrane evidence based reviews: ichthyosis vulgaris
Genetic Tests for Ichthyosis Vulgaris
Anatomical Context for Ichthyosis Vulgaris
MalaCards organs/tissues related to Ichthyosis Vulgaris:40
Skin, Heart, Bone, Thyroid, Brain, Kidney, Breast
Publications for Ichthyosis Vulgaris
Articles related to Ichthyosis Vulgaris:(show top 50) (show all 477)
Variations for Ichthyosis Vulgaris
ClinVar genetic disease variations for Ichthyosis Vulgaris:6 (show all 23)
Expression for Ichthyosis Vulgaris
Search GEO for disease gene expression data for Ichthyosis Vulgaris.
Pathways for Ichthyosis Vulgaris
Pathways related to Ichthyosis Vulgaris according to GeneCards Suite gene sharing:
GO Terms for Ichthyosis Vulgaris
Cellular components related to Ichthyosis Vulgaris according to GeneCards Suite gene sharing:
Biological processes related to Ichthyosis Vulgaris according to GeneCards Suite gene sharing:(show all 16)
Molecular functions related to Ichthyosis Vulgaris according to GeneCards Suite gene sharing:
Sources for Ichthyosis Vulgaris


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Management of Depression and Anxiety in Cancer- with CME credits (MDCC)
This course promotes an evidence-based wholistic approach to care and management of depression and anxiety in individuals with cancer. The content and structure of the course is based on the Pan-Canadian Practice Guideline: Screening, Assessment and Management of Psychosocial Distress, Major Depression and Anxiety in Adults with Cancer.
Available online, on-demand at any time this course consists of six modules, and is open to all clinicians working in cancer care.
This continuing education event is held under the auspices of Continuing Professional Development, Faculty of Medicine, University of Toronto and de Souza Institute, University Health Network.
- College of Family Physicians of Canada – Mainpro+: This one-credit-per-hour Group Learning program meets the certification criteria of the College of Family Physicians of Canada and has been certified by Continuing Professional Development, Faculty of Medicine, University of Toronto for up to 11.5 Mainpro+ credits.
- Royal College of Physicians and Surgeons of Canada – Section 1: This event is an Accredited Group Learning Activity (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada, approved by Continuing Professional Development, Faculty of Medicine, University of Toronto. You may claim a maximum of 11.5 hours (credits are automatically calculated).
Emotional distress is common in cancer. Take this course to:
- Understand more about risk factors for anxiety and depression in cancer
- Obtain the latest information on best practices in distress management
- Reduce patients' physical and psychological suffering and enhance quality of care
This course has been designed for front-line providers, including physicians; nurses; and allied health care providers.
The following areas are covered in the modules:
- Prevalence and risk factors for anxiety and depression in cancer patients
- The bio-psycho-social etiology and pathophysiology of anxiety and depression
- Elements involved in initial screening, comprehensive assessment and focused assessment
- Assessing the risk of immediate harm
- Differences between suicidal ideation, request for Medically Assisted Dying, or Desire for Hasterned Death
- Clinical pathway based on distress severity
- Psychosocial treatment options
- Pharmacological treatment options
- Practical team-based interventions across the continuum of emotional distress
The Management of Depression and Anxiety in Cancer course was developed in collaboration between Cancer Care Ontario (CCO) and de Souza Institute.
Fee (CAD): $ 380.00

subset: commoncrawl


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Actor Nick Nolte spoke out recently on that infamous mug shot 16 years ago.
Nolte, 76, was arrested for driving under the influence in 2002 on the Pacific Coast Highway near his Malibu home. A photo shows him wearing a Hawaiian shirt and his hair in disarray. It's become the source of Internet memes and jokes the world over.
Fox News: Nick Nolte talks 2002 arrest photo: 'I looked like an asylum inmate out for a lark' https://t.co/vJKmEdCisa pic.twitter.com/9tmdGlMdiu
— LINKS TO (@AtoZLinksTo) January 17, 2018
"GHB was one substance I ran into that I shouldn't have messed with," Nolte told People in a recent interview about his upcoming book, "Rebel."
"I took GHB prior to going to the gym for a long workout," the "48 Hours" star wrote in his book, as People reported. "A strong dose made me feel great, yet I knew I was repeating with GHB the addictive cycle I'd been in before."
GHB, or 4-hydroxybutanoic acid, is an intoxicant and central nervous system depressant. It's been used as a date-rape drug.
Before his arrest, Nolte said that he had driven to an Alcoholics Anonymous meeting at a church near his Malibu home. When he got to the church, the drugs began to kick in, and he drove off because he wasn't in any shape to attend the meeting.
"I was a mess and driving on the Pacific Coast Highway," he said. "I'm told six drivers called 911 to report a big sedan weaving on the wrong side of the road."
Rebel by Nick Nolte goes on sale 1/23. Catch him at his signing in #LA at the Skirball Cultural Center with @BookSoup on 1/31. Find out more and get tickets here: https://t.co/qletigKiEf pic.twitter.com/2Vnug6Glh1
— HarperCollins (@HarperCollins) January 17, 2018
Nolte was arrested and taken to a nearby hospital for blood tests.
A police officer then asked him to take his photo, to which he agreed. It became the now-infamous image.
Nick Nolte on his infamous 2002 mug shot: I looked 'like an asylum inmate out for a lark' https://t.co/eC6O2YRaJW
— Entertainment Weekly (@EW) January 17, 2018
"It went viral — my hair wild, my expression unsettling, looking like an asylum inmate out for a lark. In 1992, People magazine had named me the Sexiest Man Alive, and now, 10 years later, I looked to all the world like a madman," he said.
It was a wake-up call, he said.
"It took thirty days to wean myself off GHB and then I flew home. I was a renewed and fortunate man," he said.
Recommended Video:


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Lips augmentation in Dubai is a cosmetic procedure used to alter the shape of lips by giving you plumper and fuller lips. The most commonly used for lip augmentation procedure these days uses injectable fillers called dermal fillers.
There are many types of fillers available these days that are injected into the lips and area around the mouth to make it more appealing. The most common type of fillers contain substances that help in combating the wrinkles such as hyaluronic acid and its derivatives. Hyaluronic acid is a substance in the body that is responsible for increasing lip volume. In the past collagen fillers were common filler but it is not used anymore because the new fillers last for longer time.
Fillers are used for changing and improving the appearance of lips. The effects that fillers have on a person are following:
It can change the shape of your lips.
The volume of lips can also be changed to suit different people.
Fillers can also change the structure of lips.
The fillers used for lip argumentation in Dubai can last from 6 months to 12 months and it depends upon the metabolism and other factors of the person that receives it. It varies from person to person.
After the injection gel in the filler will support the tissue and shape of the lips to make them more firm some of the benefits of these dermal fillers are the following:
Any lumps created due to the movement of lips can be easily dissolved due to the soft nature of fillers.
The amount of filler injected into the lips can be controlled and the doctor will have control over the increase in the volume needed.
The results of this type of treatment last for longer but these results are not permanent.
There is no chance of an allergic reaction because the filler is made from the material that is naturally found in the body. However, if you are allergic lidocaine you should tell your doctor before the treatment.
The procedure is a non-invasive treatment which is the reason that little swelling or bruising will occur.
The procedure is performed quickly in the doctor's office with minimum downtime. In the case of fat injection downtime of the procedure is increased because liposuction is also performed to remove fat from another part of the body.
During the procedure, topical or local anesthetic is applied to reduce the discomfort. In some cases, nerve block injection is used to completely numb the lips. This type of anesthetic is also used by dentists during the procedure to numb the mouth.
In this treatment, the area where the procedure needs to be performed is marked carefully after that small fine needles are used to inject the filler into the lips. You are expected not to put any pressure on the treated area. The usage of lipstick and other lips product should be avoided after the procedure until your lips are fully healed.
The difference is easily noticeable and you will be able to easily tell the difference immediately after your lips are healed.
Side effects of this treatment are temporary and usually last for a few days. These effects are the following:
Swelling and bruising in the lips area might occur.
The cold sore or fever blister might activate again around the lips and surrounding area this is also known as herpes simplex.
Bleeding can also occur from the area of lips where the filler was injected.
Redness, as well as tenderness at the area of injection, might also be expected.
The more serious cases include:
Infection, Scaring, Ulceration or stiffening of the lips.
An allergic reaction could cause swelling, itching or redness around the area of lips.
In case of severe and prolonged swelling bruising might last for one week to 10 days.
The imbalance between the sizes of lips might occur (parts of lips will have a different size)
If the filler is injected into the blood vessel than it can cause the loss of tissue.
Lumps and irregularities might occur in the lips.
If you have extreme swelling or if you have a fever then call your doctor and let him or her know.
The cost of this treatment varies for different people. It will depend upon the factors such as:
The type of lip augmentation performed.
The number of injection needed.
Usually, patients won't need more than one to two injection, the cost of one injection starts from AED 1750. Most Health insurance won't cover the expenses of the procedure as well as problems associated with the treatment because it is considered a cosmetic procedure.
Lips augmentation can give you the lips that you always desired and you won't even have to worry about surgery. However, you should keep in mind that lip augmentation is not a permanent procedure and the effects will wear off over time.
Dubai Cosmetic Surgery offers the best lip augmentation in Dubai. We also offer free online consultation with highly skilled doctors. All you need to do is fill the form below and we will contact you in no time.
Fill in the form to get Consultation100% Financing with 0% Interest


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Welcome to our research center! We've put together a library of information on important financial topics that we believe you'll find helpful.
Simply click on one of the general financial topics below and you'll find a selection of easy-to-understand information sheets about related financial concepts and strategies. This information is updated regularly to reflect the latest facts, figures, legislation, and economic trends.
SEP IRAs
A SEP IRA is a type of plan under which the employer contributes (up to a certain limit) to an employee's IRA.
SIMPLE Plans
The SIMPLE plan may appeal to small business owners as it is easy to set up, administer, and allows for a tax deduction.
IRA Rollover
If you leave a job or retire, you should consider your options regarding your employer retirement plan assets.
Why Purchase Annuities
Annuities, an insurance-based financial vehicle, can provide many benefits that retirement investors might want.
Retirement Plan Distributions
When receiving money accumulated in your employer-sponsored retirement plan, you have two options: lump sum or annuity.
Traditional IRAs
If you do not participate in an employer-sponsored retirement plan, you might consider a traditional IRA.
Roth IRAs
Qualified Roth IRA distributions in retirement are free of federal income tax and aren't included in gross income.
Mutual Funds
A mutual fund is a collection of stocks, bonds, and other securities with certain benefits and risks.
An annuity is a flexible financial vehicle that can help protect against the risk of living a long time because it provides an option for a lifetime income.
Risk Management
Why Purchase Life Insurance
If you have a family who relies on your income, it is important to have life insurance protection.
Annuities as an Insurance Product
An annuity is a contract between you and an insurance company to pay you future income in exchange for premiums you pay.
Business Owner Policies
A business owner policy is an insurance package that assembles the basic coverages required by a business owner in one bundle.
Life Insurance for Business Owners
Company-owned life insurance is one way to help protect a business from financial problems caused by the death of a key employee.
Split-Dollar Life Insurance
Split-dollar life insurance is an arrangement to purchase and fund life insurance between two parties.
Last-Survivor Life Insurance
Couples who want to help protect their legacy from estate taxes could consider last-survivor life insurance.
Term Life Insurance
Term life insurance differs from permanent forms of life insurance in that it offers temporary protection.
Whole Life Insurance
Some of the pros and cons of whole life insurance.
Universal Life Insurance
Consider a universal life insurance policy if you want the flexibility to change your premium or death benefit.
Variable Life Insurance
Variable life insurance gives you the control to allocate your account value among a variety of investment options.
Auto Insurance
Even if your state doesn't require certain types of auto insurance, it may be wise to purchase multiple types to ensure you are covered for a variety of situations.
Insurance Claims
When it is time to make an insurance claim, it helps if you are familiar with your policies and the steps you should take to file a claim.
Maximizing Your Insurance Benefits
Several factors could undermine the financial security provided by the proceeds of your life insurance policy.
Insuring Your Future
To help you choose insurance wisely, determine how much coverage and what kind of policy is best for your situation.
Protecting Your Home
Since your home is one of your greatest assets, you should make sure it is adequately protected. That's where homeowners insurance enters the picture.
Types of Health Coverage
There are three basic types of medical insurance plans: fee-for-service, managed care, and high-deductible health plan.
Additional Liability Coverage
Consider additional liability insurance to help protect you from the potentially devastating effects of liability lawsuits.
HMOs and PPOs
Selecting health insurance is often one of the most important decisions you will make. Do you know the different types?
Evaluating Insurance Companies
Using a financially sound insurance company is an important part of ensuring your family's financial security.
Long-Term Care Costs
The odds of needing long-term care increase as you age. Prior planning can help protect you from financial ruin.
Medicare Coverage
Medicare is the federal health insurance program for those persons age 65 and over. But what does it cover?
Long-Term-Care Needs
If you were to suffer an illness or disability that required long-term nursing care, would you be covered?
Types of Life Insurance
When selecting a life insurance policy, examine all your options, as well as the positives and negatives of each type.


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Juan Fuster Zaragoza Avenue gains 70 parking spaces for residents and 70 for motorcycles
Juan Fuster Zaragoza Avenue counts from today with a single lane of circulation and happens to be of unique direction, with entrance by Ametlla del Mar and exit by Almirante Bernat de Sarrià. As reported by the councilman of Mobility, José Ramón González de Zárate, these changes in the configuration and traffic of the avenue have allowed "create 70 new parking spaces for residents and 70 more for mopeds and motorcycles", by reconversion of the lane of circulation eliminated for parking front and the liberation of the space that until now occupied 36 containers of waste collection of lateral load.
The councillor explained that these 140 new parking spaces "are located in the lower part of Juan Fuster Zaragoza Avenue, the closest to Almirall Bernat de Sarrià"; while the "110 blue zone parking spaces" are maintained, which have been concentrated in the area closest to Ametlla del Mar Avenue and which guarantee the rotation of vehicles "to serve the health center and the shops
With the creation of new exclusive parking for registered residents, the 'Residents' Zone' already exceeds 300 parking spaces in Rincón de Loix, and increases up to 3,300 parking spaces throughout the city.
De Zárate, who also manages the Street Cleaning department, recalled that the changes in Juan Fuster Zaragoza avenue also affect the garbage collection system, which is no longer side-loading and becomes rear-loading. Hence, it has been proceeded to the withdrawal of "36 containers that were fixed on the street", which have been replaced by traditional containers that each community will take to the street at the scheduled time.
The councillor has anticipated that during the next few days "more bins will be installed" and the urban scene of the avenue will be reinforced with "the installation of rubber in the tree's tree pits".


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Life Jacket, Hi-Viz & Work Wear Harness
In some work environments it is not always possible just to wear the traditional full body safety harness over the top of existing work wear, in some occasions the safety harness has to be built into work wear for either ease of use of the wearer or due to other protection issues that might arise.
Some situations for example on construction sites or around the railway, HI-VIZ vest / jackets are mandatory to be worn but wearing a fall protection safety harness with this isn't always comfortable or convenient so certain manufacturers now offer a safety harness with built in Hi-VIZ vest or in some occasions also built into Jackets as well.
In some situations in particular the Offshore or Water industries that you are required to wear a life jacket in conjunction with a safety harness which isn't always the most convenient or comfortable, so TRI now offer a safety harness with built in life jacket to solve both of these issues.
Sometimes the working environment means that a harness would be exposed to substances in the atmosphere or within the working area that would mean the fall arrest safety harness would no longer pass pre use inspections. In these situations placing a safety harness within the work wear / overalls themselves would mean extending the lifespan of the harness as well as providing more comfort to the user.
If you are interested in these safety harnesses or would like to discuss them further please do not hesitate to contact the TRI sales team.


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Technology news for New Zealand's largest enterprises
Workforce management
These search results are from across the Techday network of sites
26 Jun
Workday expands HR offerings for workforce optimisation
Workday has this week released several new HR offerings designed to assist organisations with optimising their workforces in the post COVID-19 environment.
12 Jun
Five things millennials look for in their next role
Apart from being digital natives, millennials aren't really that different from other generations of workers and, of course, they're all individuals.
13 May
Workforce transformation at the heart of business success in COVID-19 era
"The focus must be on supporting a different type of workplace characterised by geographically dispersed team members, a mix of employee-owned and company-provided devices, and an ongoing need for collaboration."
08 May
Gartner updates 2020 future of work trends for post-pandemic world
The post-pandemic world will bring workplace change in terms of health support, remote working, gig workers, and employee tracking.
26 Mar
Educating the next generation: what skills will they need in the future workplace?
The Australian workplace is now moving into an era where some hard skills are starting to expire.
10 Mar
Your dynamic workforce just got a whole lot more dynamic
Overnight, your dynamic workforce just got even more dynamic - and not in the ways that anyone particularly wants.
08 Mar
IWD 2020 interview: Smart WFM's Candice Lloyd
As a celebration of International Women's Day, we're running a series of interviews with women in technology. Smart WFM's Candice Lloyd shares her thoughts.
12 Feb
Three trends set to define work in the new decade
With a new decade underway, organisations must think more about culture and ways of attracting, engaging with, training and retaining employees. Not everyone is prepared to trade free lunches for sixty hour weeks.
05 Feb
Business enthusiasm for emerging tech clashes with cybersecurity woes - CompTIA
The report also finds spending on hardware, software, services and telecom is projected to reach almost $5.2tn globally.
13 Dec
Humanforce designs accessibility-compliant app for those with disabilities
"Employers can be doing much more to make the workplace more inclusive for the people with a disability currently working and also to increase employment of the many people with a disability looking for work."
21 Oct
HPE rolls out 26 weeks' paid parental leave for A/NZ employees
As part of the Work That Fits Your Life program, parental leave, parental transition support, retirement transition support, and Wellness Fridays are all available as career support options.
21 Oct
Gig economy fuels 'portfolio careers' as the new normal
According to HNRY founder James Fuller, the 'future' of work is actually the 'present' of work.
02 Oct
Aussie company launches new workforce optimisation software
Smart WFM, the Australian HR workforce management consultancy, has launched Apitome software suite to help businesses optimise their workforces.
09 Jul
Aspect Software announces workforce management offering for Azure
Companies have unique requirements for deployability and migration, driven by security, privacy, regulatory and other internal factors.
17 Sep
Exclusive: AI is the key to intelligent digital workforces
"RPA is considered to be one of the most transformative technologies in decades."
22 Aug
A/NZ organisations are resetting their approach to collaboration technology
More than half of A/NZ employees consider work something they can do regardless of time or location.
09 Jul
The importance of strong analytics for HR and business success
Better workforce management can streamline costs and maximise efficiency for businesses.
09 Jul
Keep your employees on task with cloud-based desktop surveillance
Controlio is a cloud-based surveillance system that tracks web and application usage on Windows PCs.
09 May
Teleopti empowers workforce management software with AI
From now on, anyone using Teleopti WFM will be working with an AI-infused WFM solution.
17 Nov
The power of people in today's digital-service economy
Jeff Arnold, Unit4 A/NZ sales director examines how businesses can proactively manage their workforce by adopting technology to increase efficiency.
26 Sep
Microsoft says first-line workers are underused in digital transformation
The company cites an online survey of 1,390 working adults which was commissioned by Microsoft and completed by research firm, YouGov.
31 Aug
After a new job? Here's two of the top 10 best places to work in AU
For those unhappy with their job, here's a couple of companies that have made it into Australia's top ten best places to work.
02 Mar
Xero forms workforce management partnership with Deputy
"We look forward to working closely with Deputy to deliver best in class time savings solutions to more small businesses."
24 Jan
OpenView invests US$25m in A/NZ workforce management company
The funding will be used to rapidly grow Deputy's team across offices around the globe, including Sydney.
Next ›
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Disability, Mental Health, Aged Care, and Individual Support – Community Service Courses in Melbourne
CHC52015 Diploma of Community Services
- This qualification reflects the roles of community services, case management and social housing workers involved in the managing, co-ordinating and/or delivering of person-centred services to individuals, groups and communities
- This course provides you with the skills and knowledge to undertake job roles such as: Case coordinator, Case worker or manager, Community services worker, Coordinator family services, Early intervention worker, Youth Worker
CHC33015 Certificate III in Individual Support
- This qualification provides a nationally recognised qualification delivered with a specialisation in Aged & Community Care. This qualification is for people who wish to work in an aged care facility and in the home and community care sector
- This course provides you with the skills and knowledge to undertake job roles such as: Accommodation support worker, Assistant in nursing, Personal care assistant, In-home respite worker
CHC43315 Certificate IV in Mental Health
- This qualification reflects the role of workers who provide self-directed recovery oriented support for people affected by mental illness and psychiatric disability
- Work involves implementing community based programs and activities focusing on mental health, mental illness and psychiatric disability
- Work is undertaken in a broad range of community contexts
CHC43115 Certificate IV in Disability
- This qualification reflects the role of a Disability Support worker in a range of community settings and clients' homes. The Disability Support worker provides support in a manner that empowers people with disabilities to achieve greater levels of independence, self-reliance, community participation and wellbeing
This course will provides you an opportunity to enter into the workforce involving job roles such as: Behavioural support officer, Disability support worker / Disability officer – day support, Community-based support worker, and more
CHC43015 Certificate IV in Ageing Support
- This qualification reflects the role of support workers who complete specialised tasks and functions in aged services; either in residential, home or community based environments
This course will provides you an opportunity to enter into the workforce involving job roles such as: Accommodation support worker, Hostel supervisor, Personal care worker, Care supervisor / team leader, Program coordinator, Day activity worker & Support worker
CHC43215 Certificate IV in Alcohol and Other Drugs
- This qualification reflects the role of entry level workers who provide services and interventions to clients with alcohol and other drugs issues and/or implement health promotion and community interventions
Work is undertaken in contexts such as community based organisations, withdrawal services, residential rehabilitation services and outreach services under the guidance of other practitioners and professionals, with limited responsibility and within established parameters
Melbourne Community Service-Based Courses in the CBD and Various Other Locations
Are you looking for a Community Service course? Learn the skills and knowledge needed for a career in: Individual Support, Mental Health, Disability Support, Aged Care, Alcohol and Other Drugs Support with our certificate and diploma courses at 400 Queen Street, Melbourne, Box Hill, Werribee and various other locations. Our comprehensive training will teach you everything you need to know to start working in a community services field as well as teach you advanced techniques to take your career to the next level.
Student Testimonials and Reviews
Kevin Samy Rau
CHC33015 Certificate III in Individual Support
2018 Graduate
"TMG College Australia's diversity enables me to speak English and other languages as well. The atmosphere of the college is really wonderful. My trainer has always been my pillar, I can rely on her at anytime."
Fabian Andres Prado
CHC52015 Diploma of Community Services
2018 Graduate
"I'm studying a Diploma of Community Services. All of the trainers here have a good level of knowledge. My trainer, is very kind and fun! The city campus is good, I like to spend my free time here playing table tennis."
Babatunde James Akinda
CHC52015 Diploma of Community Services
Graduated September, 2018.
James recently graduated TMG College Australia's Diploma of Community Services. "TMG College have good teachers that are professionals. They see to any concerns raised by the student studying in their school."
"I loved my trainer because she was very easy to approach. Anytime me or other students were having difficulties in areas of our study, she was always ready to help us out."
"All of the staff at TMG are friendly, the teachers are interesting and the school environment is very neat and constructive."
"Life in Melbourne is very cool, lively and fun."
"TMG is a very good school, I enjoyed my study and my stay throughout my course. I will miss the staff and all my friends who are still studying there."


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last night, after a very long night at work, i walked in to these:
and a beautiful hand-written card. valentine's day has never been one of my favorite holidays, but travis always makes it special. we have been together for 4 years, and i couldn't imagine sharing my life with anyone else. by this time next year we'll have a 6 month old to share in our love. i can't wait!


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- A woman from Kansas City, Missouri was dumped by her boyfriend after a discounted microblading procedure left her with four eyebrows.
- Jami Ledbetter was born without eyebrows so her daughters bought her a $250 Groupon for microblading.
- The 42-year-old mom ended up paying $1000 to get a licensed tattoo artist who has been correcting her botched brows using a pigment lightening solution.
A single mother from Kansas City, Missouri has revealed that the man she's been dating dumped her after a botched microblading treatment left her with four eyebrows.
Jami Ledbetter, who was born without eyebrows, and was so excited when her daughters gifted her a $250 Groupon voucher in November 2018 to get semi-permanent tattooed brows.
But after the discounted procedure, the 42-year-old lost her self-confidence and was too self-conscious to go out.
"I would never wish this on my worst enemy. What it's done to my self-confidence, it's been hard," the mom of three told Fox 4 KC. "I was devastated. I was even dating a guy, and he stopped dating me at that point."
Microblading is a procedure that involves tattooing someone's eyebrows on with tiny needles or a small blade, according to Fox News.
Ledbetter thought the person who performed her microblading treatment was "certified." However, the practice is not licensed in Missouri.
She was so horrified by the results of the procedure that for almost three months, she only went out to work and food shopping.
"It was pretty painful," Ledbetter said. "I tried to have a good attitude, but it burned a lot. It kind of felt bruised."
The single mom tried to conceal the two extra eyebrows using makeup but nothing worked.
Eventually, she was referred to Kara Gutierrez, a licensed tattoo artist who specializes in permanent cosmetics, including tattoo removal. The owner of the salon Spot On Beauty in Lee's Summit was shocked to see Ledbetter's botched eyebrows when she first saw her in February.
Gutierrez has been using Li-ft — a pigment lightening solution — on Ledbetter's extra eyebrows to remove them. It will cost her at least $1,000 to have a full removal procedure.
'If I would have known it was going to turn out like this, I probably would've never done it at all,' Ledbetter said.
The unidentified woman who performed her original botched microblading procedure is reportedly no longer in business.
Source: Fox News


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Price: $14.00
Quantity: 1 available
Book Condition: Very Good
Hardcover with pictorial dust jacket, edition not stated, 786gms, 403 pages. Opus Dei is the most controversial - and mysterious - force in the Catholic Church. Here, John ALlen uncovers its real nature. Book is in very good condition with minor general wear and tear, dust jacket is in good condition with mild shelf wear, otherwise no other pre-loved markings. Attached picture is of actual book. Purchase more than 1 item and save money with combined postage. And if you can't find the title you're looking for - why not ask us direct. With over 30,000 books in stock we can't list them all!
Title: Opus Dei: Secrets and Power Inside the Catholic Church
Categories: Religion/Spirituality,
Edition: Edition Not Stated
Publisher: Camberwell, Australia, Penguin Group: 2005
ISBN Number: 0713999012
ISBN Number 13: 9780713999013
Binding: Hard Cover with Dust Jacket
Book Condition: Very Good
Jacket Condition: Good
Size: 8vo - over 7¾" - 9¾" tall
Item: 1.00 Item
Seller ID: REL122
Keywords: CHRISTIANITY, RELIGION, CATHOLIC, CATHOLICISM, CHURCH, OPUS DEI,


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Cheer for Your Team Ornament – Fan #1 – Female Personalized Christmas Ornament
She is a true sports enthusiast. This number one fan is dedicated to her home team whether it is a professional team or a school team. She is easily spotted with her #1 fan styrofoam hand and her team flag in her other hand as she screams to support her favorite team. She loves to go to the games and is proud to have the title of #1 fan.


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This topic contains 0 replies, has 1 voice, and was last updated by Barreto Silva 1 year, 10 months ago.
It could have a button inside the piano roll that could hear a chord for example without giving play, as if it were a preview, a button called playback same has in FL Studio.
To better understand, watch this video, in 19 minutes and 45 seconds of the video, to see this function.
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Offseason went by quickly. As usual, as soon as I realized what could I do with the extra time it was time to get back to training.
At the beginning of the month I spent a few days in my hometown on the south. The weather is great down there. Sunny with 20-24C and even the sea temperature still hovers around 20C. Quite a bit different from grey weather in Zagreb. At least it's not too cold so I'm trying to do some longer rides outside while I still can.
I started to increase my pool time. Since swimming is still my weakest discipline I'll have to spend another winter smelling of chlorine.
The injury that forced me to DNF in Barcelona is almost healed, but because of that "almost" my runs are still short and rare.
I've also started to plan my race schedule for the next season. I'd like to spread out my season a little bit and do 3 Ironman distance races. It's not easy to do it within Europe and traveling overseas might be out of my budget so we'll see.
Here's how autumn looks on the south of Croatia:


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19 Backpacking Trails near Driggs, Idahofirst prev 1 next last
Showing Backpacking Trails within 50 miles Distance miles of Driggs, ID, USA City, Zip, or Address
Darby Wind Cave
Driggs, Idaho7.6 miles E
Darby Wind Cave is a beautiful hike full of waterfalls, wildflowers, streams, and mountainous views. The sites you see will depend on the time of year you visit but it will always be beautiful and...Backpack, Cave, Hike, Rock Climb 15.7-19.2 mi
Alaska Basin
Driggs, Idaho10.0 miles E
The Alaska Basin Trail is a stunning trail through the Jedediah Wilderness near Driggs, Idaho and goes East into Wyoming, just outside of Grand Teton National Park. The trail is wide...Backpack, Hike, Horseback 4.0 mi
Devil's Stairs
Driggs, Idaho10.1 miles E
Just to the West of Table Rock is this often overlooked trail less traveled by, full of beautiful meadows and beautiful views all its own. The trail begins from the same campsite as the Table Rock...Backpack, Hike 4.9 mi
Amphitheater Lake
Alta, Wyoming16.5 miles E
Backpack and Hike near Alta, WyomingBackpack, Hike 1.4-4.0 mi
Phelps Lake
Jackson, Wyoming18.2 miles E
The Phelps Lake trail, located in Teton National Park, Wyoming, is in one of the most scenic locations of the park. Usually overshadowed by nearby Jenny Lake, it can often be missed by visitors of...Backpack, Camp, Dive, Hike, Swim 3.9-14.4 mi
Grand Teton
Jackson Hole, Wyoming18.5 miles E
At 13,770 feet above sea level, the Grand Teton towers majestic over Southeastern Idaho and Western Wyoming, making it a life goal of many amateur climbers and outdoor enthusiasts. The...Backpack, Hike, Rock Climb 13.8 mi
Middle Teton
Jackson Hole, Wyoming18.5 miles E
At 12,804 ft above sea level, the Middle Teton is a challenging and beautiful hike from the trailhead all the way to the peak. The first part of the trail is dirt trails through the trees. That...Backpack, Hike, Rock Climb
Teewinot Mountain
Jackson Hole, Wyoming18.5 miles E
Backpack and Hike near Jackson Hole, WyomingBackpack, Hike 24.3 mi
Cascade Canyon Trail
Jackson Hole, Wyoming19.5 miles E
This hike starts the same as the Jenny Lake trail, then after you pass the boat dock, it takes off up Cascade Canyon just to the north of Teewinot, Mount Owen, and the Grand Teton along Cascade...Backpack, Hike 0.1-7.3 mi
Leigh Lake
Alta, Wyoming19.5 miles E
Enjoy the grandeur of Grand Teton National Park just a little ways off the beaten path. Leigh Lake rests underneath the majestic Mount Moran. The waters of Leigh Lake flow almost directly into String...Backpack, Canoe, Hike, Kayak 10.5-16.2 mi
Paintbrush Canyon
Alta, Wyoming19.6 miles E
Beautiful trail along String Lake, Leigh Lake, and Lake Solitude. For even more solitude, scramble up the rocks to Micah Lake for a beautiful view and even fewer people. You won't find...Backpack, Hike 5.6-8.3 mi
Palisades Creek Trail / Lakes and Waterfall Canyon
Irwin, Idaho23.0 miles S
Palisades Creek Trail is located about 50 miles southeast of Idaho Falls and about 60 miles west of Jackson Hole WY in Swan Valley Idaho. The four mile hike up to lower Palisades Lake or the 6.2 mile...Backpack, Camp, Hike, Horseback, Mountain Bike 3.9 mi
Little Elk Creek Trail
Irwin, Idaho26.7 miles S
Backpack, Hike, Horseback, and Mountain Bike near Irwin, IdahoBackpack, Hike, Horseback, Mountain Bike 13.8 mi
Big Elk Creek
Irwin, Idaho27.7 miles S
Big Elk Creak Campground is a very versitile campground with plenty of activities to keep busy. Campgrounds are available, with three group sites that include picnic tables and campfire rings. There...Backpack, Camp, Canoe, Hike, Horseback, Kayak 3.2-47.0 mi
Yellowstone Branch Line Trail
Ashton, Idaho29.2 miles N
Yellowstone branch line trail runs from Warm River to the Montana border totaling 39 miles. There are a few places to jump on and off the trail as well as a few smaller trails that branch off of this...Backpack, Cross-country Ski, Hike, Horseback, Mountain Bike 13.2-13.5 mi
Bear Creek Hot Springs
Irwin, Idaho31.5 miles S
Bear Creek Hot Springs is a 15 mile out and back trail with a hot spring at the end. The trail is not well marked and is only recommended for very experienced outdoorsmen and primarily used for...Backpack, Camp, Hike, Horseback, Hot Springs, Mountain Bike
Blue Miner Lake
Jackson, Wyoming31.9 miles E
Backpack and Hike near Jackson, WyomingBackpack, Hike
Union Falls
South Entrance, Yellowstone National Park34.5 miles N
Backpack and Hike near South Entrance, Yellowstone National ParkBackpack, Hike 6.9 mi
Heart Lake Trail
Grant Village, Yellowstone National Park48.3 miles NE
The trail is very clear and leads to a moderate eight mile hike to Heart Lake. This hike has many possibilities. Day hikers need to push their time to make sure they are on the trail early to allow...Backpack, Camp, Hike, Hot Springs


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Vanitas Coasters by Tomasine Gahn Set of 4 Designer Coasters - Skull Pope Pink
VA003Regular price £79.00 Sale price £39.95 Save 49%
"It's actually less about the coaster and more about the conscious choice of vanity; a reminder of the transience of life and the futility of pleasure."
The Vanitas coasters are Tomasine's first products to be launched from her Table Top/Home Decor collection. The coasters are inspired by the Roman renaissance and the Dolce Vita lifestyle in her old hometown of Rome. The idea was to incorporate different art styles. Renaissance symbols, drawings, modern material and contemporary technology.
"I wanted to create Art and Design in one single object meeting our needs.
The perfect gift for every occasion, gender and age.
A functional Art and Design object in the luxury segment.
Perfection when it comes to craftsmanship, local thinking and material details"
The Vanitas Coasters are something that everyone can enjoy everyday. At home in our kitchen or living room. In a bar, hotel lobby, club, yacht or at a restaurant. "The Vanitas Coasters are my contribution to the everyday life that should consist of pleasure, love and laughter".
The Vanitas Coasters can be utilized in many ways and do not only protect your furniture from stains but are just as nice as pure coffee table decoration matching the colors your flower bouquet of choice. The many color combinations makes it easy to choose your personal favorite depending on occasion and edgy details needed. Like at the fine dining or the dinner party; If your guests are shy at first, the Vanitas Coasters are the perfect conversation pieces to discuss the hidden thoughts of Vanity.
Always Available
Everything you see on the Burton Blake website is available and ready to be dispatched to you. If for any reason an item is not available it will be removed from the site until it is back in stock.
Free UK Delivery
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Delivery to Europe is £9.95 and the rest of the World is £39.95.
Delivery Times
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Easy Returns
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PORTLAND – Ryan Scott Uhuad, 43, of Portland, formerly of Jay, passed away peacefully surrounded by his loving family on Thursday, April 11, 2019, at his home in Portland. He was born on Dec. 29, 1975, in Farmington, Maine, to Generoso "Gene" and Cheryl (McDonald) Uhuad of Jay.
He was a 1995 graduate of Jay High School. Ryan will always be remembered as a gentle giant, a passionate fan of McDonald's hamburgers, and an elaborate story teller. He was also an avid bowler, gameshow enthusiast, and lover of pop music. He loved spending time with his family and helped those around him appreciate the little things in life.
Ryan is survived by his parents, Gene and Cheryl of Jay; his brother Randy Uhuad and his wife Betsy of Saco, his sisters Ashley (Uhuad) Roy and her husband Alex, and Kristen (Uhuad) Hewitt and her husband David, all of Marion, Mass.; maternal grandmother Marguerite McDonald of Jay; nephews Hunter and Henry Uhuad; and multiple aunts, uncles, cousins, and his dear friend, Mary Dunlap. Ryan is predeceased by his maternal grandfather, Carroll McDonald, and paternal grandparents, Jose and Maxima Uhuad; uncles, Domingo and Jose Uhuad; and cousin, Jennifer McDonald.
The Uhuad family would like to extend their sincerest gratitude to Ryan's group home, Port Resources, for providing exceptional care, and for being a second family to Ryan. Messages of condolence may be sent to: www.finleyfuneralhome.com.
Family, friends, and others whose lives Ryan touched are invited to attend his memorial service at 1 p.m., Saturday, April 20, at FINLEY FUNERAL HOME, 15 Church St., Livermore Falls, Maine. Visitation will be held from 12-1 p.m., prior to the service. Interment will be held at Pleasant Hill Cemetery, 100 Fayette Rd, Livermore Falls.
In lieu of flowers,
the family asks that donations be made to:
Port Resources
280B Garnett Dr.
South Portland, ME 04106 or via website at


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This is the Waterman Ici et La fountain pen. It came to me in a vibrant purple, a refreshing change from my black and silver. The colour is the finish of the fine writing instrument, but in the review that's only the start.
The sleek and slender body makes it feel at home in the hand, it medium nib gives a regimented flow of ink at all times. The Waterman Ici et La fountain pen comes equipped for use with cartridges or a converter for those of us used to filling our fountain pens up.
The Waterman Ici et La fountain pen seems somewhat shorter in length than my other fountain pens, this I think makes it an easier choice for use in Filofax or dairy fanatics. The Waterman Ici et La is a must for all fountain pen addicts, just like me. Well worth a buy as a gift, or just treat yourself.
You can get in touch with our guest blogger Thehappysciber on Twitter


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Little more than three months after naming the former head of Taco Bell as its CEO, Chipotle Mexican Grill announced it will relocate its headquarters from Denver to Southern California—also home to Taco Bell.
Chipotle's new corporate home will be Newport Beach, Calif., with a consolidated shared services center in Columbus, Ohio. The relocation will affect some 400 employees in Denver and New York in the last quarter of 2018, with some being offered relocation and retention incentives, the company said.
The move to California will "help us drive sustainable growth while continuing to position us well in the competition for top talent," Chipotle CEO Brian Niccol said in a statement.
"In order to align the structure around our strategic priorities, we are transforming our culture and building world-class teams to revitalize the brand and enable our long-term success," he added.
The massive move will take place over the next six months, as Chipotle transitions offices in Denver and New York to California and Ohio. The Newport Beach office will house the chain's operations, business development, marketing, communication, finance, supply chain, food safety, technology, human resources and other corporate functions.
The existing shared services center in Columbus will grow from 100 to more than 250 employees, allowing the company to consolidate and standardize support services.
Chipotle, widely credited with spearheading the customizable fast-casual category, opened its first unit in Denver in 1993. Its corporate headquarters have been located there ever since.


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Organic Farm
As part of our goal to preserve the agricultural history of Los Poblanos, a significant percentage of the property is dedicated to organic farming. The farming model is driven by sustainability - being a good steward to the land, architecture, culture and community. Our commitment is expressed by growing ingredients organically, literally steps from the kitchen. Dedication to the agrarian past extends to preservation of our historic 1930s gardens and guests experience 25 acres of a unique and diverse landscape firsthand, creating a profound and authentic agritourism experience.
Walking farm tours are offered for guests during the warmer months, visit the Events Calendar to learn more. If you are interested in volunteering on the Farm, please click here to fill out a volunteer inquiry.
Kitchen Gardens & Artisan Farming
At Los Poblanos, we have dedicated some of our agricultural fields solely to food production for our kitchens. We proudly farm organically and sustainably. Our farmers cultivate a broad array of heirloom, native, and standard varieties of crops that are highlighted in the Rio Grande Valley Cuisine crafted in the kitchen at Campo. By collaborating closely with the kitchen, we can grow the freshest, highest quality ingredients to provide our guests with an outstanding dining experience.
Some of the native varieties we grow on the farm include Epazote, Lambs Quarters, Devil's Claw, Acoma Light Melons, Hopi Purple String Beans, Zuni Blue Corn, and Acoma and Navajo Pumpkin. These varieties provide a link to a thousand-year agricultural history in New Mexico. Not only are they locally adapted and heat- and drought-tolerant, but they are also delicious!
Our farm can provide fresh produce to the kitchen year-round by growing heat-tolerant varieties in the summer and by using season extension methods in the winter. Row-cover cloth and the unheated hoop house keep cold-tolerant vegetables safe from damaging frosts until they are ready to harvest. The Lord & Burnham Historic Greenhouse is used year-round. We plant vegetable, herb, and flower seeds in starting trays on greenhouse shelves. We take cuttings from our fields of Grosso lavender and root them and other cuttings in the greenhouse as well.
Come stay at the Inn, take one of our classes or volunteer on the farm for part of your stay if you'd like. Whatever your previous experience with farming, you'll find something here at Los Poblanos to captivate your interest.
Los Poblanos Honey Bees
In support of a perfect ecosystem owner Armin Rembe (Farmin' Armin) started keeping bees in 2005. At certain times of the year, you can taste a hint of lavender in our honey. Bee Fact: on average, a honey bee will visit 50 to 100 flowers on a collection trip.
Rose Greely Garden
The formal Spanish-style gardens around the Hacienda and La Quinta were designed in 1932 by Rose Greely, a pioneer female landscape architect. Greeley was the first female graduate of Harvard's landscape architecture program and worked primarily in the Washington DC area designing residential gardens. Coincidentally, her roommate at Harvard was John Gaw Meem's future wife, Faith. This connection through the Simms' relationship with Meem was the introduction that brought Greely to Los Poblanos, her only known work in the Southwest. The gardens feature vibrant flower beds, Spanish tile fountains, rose cutting gardens, winding pathways and mosaic stonework by "Pop" Shaffer, a folk artist who had arrived in Mountainair, NM in 1908. The entrance driveway features an allée of mature Cottonwood trees.
Judith Phillips
Judith designed the landscapes surrounding the Farm Suites at the time of their construction, utilizing more drought tolerant species than had been historically planted. This design also incorporated plants that were found in other gardens on the property to maintain familiar continuity while moving towards a more multi-functional and environmentally sensitive approach to landscape design. Judith worked with AOSA (Atkin Olshin Schade Architects) as a plant consultant in the development of the landscapes for the Field Suites, selecting species that were lower water use, edible and pollinator friendly as well as beautiful.


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KOYO WJ-243028 should be avoided in wet places, and gloves should be worn to prevent sweat from getting on.


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National Librarian Day celebrates and honors librarians. They are among the most knowledgeable people you know. When you visit your cavernous library in search of a particular book, or a specific research topic, they always quickly point you in the right direction. And, they do so with a smile.
Experts of the Dewey Decimal System, your Librarian aids and assists you in identifying and retrieving a myriad of books, periodicals, and reference material. Librarians hold a wealth of knowledge in their heads. Got a subject you are researching? Chances are, the Librarian will point you right to the book you need.
Celebrate the day by sending a card to your librarian. Visit the library today, and make certain to say hello and "Thank you" to all of the librarians.
I have lots of friends who have their library degree -some use it or their work, some have never used as intended and some are retired. My part time job in college was in the library. I loved that job! Especially my senior year when I got to work in the research area. I learned so much! I often thought about getting a masters in library science but never did - followed the accounting track instead.


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Sitting on a quaint little hill in Paro, the best part of the property is, the view it offers and easy access to Paro international airport. The simple understated property features traditional Bhutanese and modern design in its architecture. The rooms are scattered across the property amidst apple trees and series of stairs connect the rooms to the main lobby area.
Trophel Tours & Treks is accredited by Tourism Council of Bhutan (License No: 1030972) and member of Pacific Asia Travel Association (PATA) and Global Sustainable Tourism Council.


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View CME-certified poster presentations and downloadable slides covering the most up-to-date clinical trial data on melanoma from the 2018 European Oncology Congress in Munich.
Interactive Presentation
Downloadable Slides
1 AMA PRA Category 1 Credit™
Release Date
Nov 1, 2018
Expiration Date
Nov 2, 2019
Paolo A. Ascierto, MDNational Tumor Institute - Fondazione G. Pascale
Naples, Italy
Christian U. Blank, MD, PhDNetherlands Cancer Institute
Amsterdam, the Netherlands
Omid Hamid, MDThe Angeles Clinic and Research Institute
Los Angeles, California, United States
Celeste Lebbé, MDHôpital Saint Louis
Paris, France
Antoni Ribas, MD, PhDUCLA Jonsson Comprehensive Cancer Center
Los Angeles, California, United States
This activity is specifically designed for physicians, nurses, and other clinicians who are cancer specialists.
After successful completion of this educational activity, participants should be able to:
- Discuss key melanoma data from the conference
- Apply key melanoma data from the conference to clinical practice, as appropriate
Colorectal Cancer
Abstract #LBA18_PR: Durable clinical benefit with nivolumab (NIVO) plus low-dose ipilimumab (IPI) as first-line therapy in microsatellite instability-high/mismatch repair deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC)
Featured Expert: Heinz-Josef J. Lenz, MD
Abstract #LBA20: TRIBE2: A phase III, randomized strategy study by GONO in the 1st- and 2nd-line treatment of unresectable metastatic colorectal cancer (mCRC) patients (pts)
Featured Expert: Chiara Cremolini, MD
Abstract #463P: Real-world dosing of regorafenib (REG) in metastatic colorectal cancer (mCRC): Final results from the prospective, observational CORRELATE study
Featured Expert: Juan Manuel O'Connor, MD
Abstract #464P: Safety and efficacy of trifluridine/tipiracil (FTD/TPI) in metastatic colorectal cancer (mCRC) patients according to previous treatment with regorafenib in the international phase 3b PRECONNECT study
Featured Expert: Julien Taїeb, MD, PhD
Abstract #466P: Phase II trial to evaluate efficacy and tolerance of regorafenib monotherapy in patients (pts) over 70 with previously treated metastatic colorectal adenocarcinoma (mCRC) FFCD 1404 – REGOLD
Featured Expert: Thomas Aparicio, MD
Hepatocellular Carcinoma
Abstract #LBA26: Updated safety and clinical activity results from a phase Ib study of atezolizumab + bevacizumab in hepatocellular carcinoma (HCC)
Featured Expert: Michael J. Pishvaian, MD, PhD
Abstract #710P: Practice patterns and deterioration of liver function after transarterial chemoembolization (TACE) in hepatocellular carcinoma (HCC): Final analysis of OPTIMIS in Europe and Canada
Featured Expert: Jean-Luc Raoul, MD, PhD
Head & Neck
Abstract #LBA8_PR: KEYNOTE-048: Phase 3 study of first-line pembrolizumab (P) for recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC)
Featured Expert: Barbara Burtness, MD
Abstract #1045O: A phase II window of opportunity study of preoperative olaparib (O) with cisplatin (C) or durvalumab (D) or olaparib alone in in patients with operable squamous cell head and neck carcinoma (HNSCC) (OPHELIA)
Featured Expert: Amanda Psyrri, MD, PhD
Abstract #1307O: Efficacy of lenvatinib in patients with advanced pancreatic (panNETs) and gastrointestinal (giNETs) grade 1/2 (G1/G2) neuroendocrine tumors: Results of the international phase II TALENT trial (GETNE 1509)
Featured Expert: Jaume Capdevila, MD, PhD
Abstract #1314P: Efficacy and safety of telotristat ethyl (TE) in combination with lanreotide (LAN) in patients with a neuroendocrine tumour and carcinoid syndrome (CS) diarrhoea (CSD): Meta-analysis of phase 3 double-blind placebo (PBO)-controlled TELESTAR and TELECAST studies
Featured Expert: Dieter Hörsch, MD, PhD
Abstract #1316P: Impact of liver tumor burden on therapeutic effect of 177Lu-DOTATATE treatment in NETTER-1 study
Featured Expert: Jonathan Strosberg, MD
Abstract #1319P: Post-hoc analysis of CLARINET phase III study to investigate the influence of diabetic status on progression-free survival (PFS) of patients with neuroendocrine tumours (NETs) treated with lanreotide (LAN) or placebo (PBO)
Featured Expert: Filippo de Braud
Abstract #1331P: Tumour growth rate (TGR) when using lanreotide Autogel® (LAN) before, during and after peptide receptor radionuclide therapy (PRRT) in advanced neuroendocrine tumours (NETs)
Featured Expert: Vikas Prasad, MD, PhD
Abstract #LBA53: IMpower130: Progression-free survival (PFS) and safety analysis from a randomised phase 3 study of carboplatin + nab-paclitaxel (CnP) with or without atezolizumab (atezo) as first-line (1L) therapy in advanced non-squamous NSCLC
Featured Expert: Federico Cappuzzo, MD, PhD
Abstract #LBA54: IMpower132: efficacy of atezolizumab (atezo) + carboplatin (carbo)/cisplatin (cis) + pemetrexed (pem) as 1L treatment in key subgroups with stage IV non-squamous non-small cell lung cancer (NSCLC)
Featured Expert: Fabrice Barlesi, MD, PhD
Abstract #LBA62: Health-related quality of life (HRQoL) for pembrolizumab or placebo plus carboplatin and paclitaxel or nab-paclitaxel in patients with metastatic squamous NSCLC: data from KEYNOTE-407
Featured Expert: Julien Mazières, MD, PhD
Abstract #LBA63: Long-term survival in patients (pts) with advanced NSCLC in the KEYNOTE-010 study overall and in pts who completed 2 years of pembrolizumab (pembro)
Featured Expert: Roy Herbst, MD, PhD
Abstract #1469P: EVIDENS: An observational study of nivolumab-treated patients in advanced non-small cell lung cancer (NSCLC) in a real-world setting: Initial results on 1394 patients
Featured Expert: Fabrice Barlesi, MD, PhD
Abstract #LBA6_PR: JAVELIN Renal 101: a randomized, phase 3 study of avelumab + axitinib vs sunitinib as first-line treatment of advanced renal cell carcinoma (aRCC)
Featured Expert: Manuela Schmidinger, MD
Abstract #LBA31: Molecular correlates differentiate response to atezolizumab (atezo) + bevacizumab (bev) vs sunitinib (sun): results from a Phase III study (IMmotion151) in untreated metastatic renal cell carcinoma (mRCC)
Featured Expert: Brian I Rini, MD
Abstract #874P: Treatment-free interval (TFI) following discontinuation of first-line nivolumab plus ipilimumab (N+I) or sunitinib (S) in patients (Pts) with advanced renal cell carcinoma (aRCC): CheckMate 214 analysis
Featured Expert: David McDermott, MD
Abstract #875P: Characterization of response to nivolumab plus ipilimumab (N+I) or sunitinib (S) in patients (Pts) with previously untreated advanced renal cell carcinoma (aRCC): CheckMate 214
Featured Expert: Brian I Rini, MD
This educational activity is supported by grants from Bayer HealthCare Pharmaceuticals, Inc.; Bristol-Myers Squibb; Ipsen; and Merck and Co, Inc.
Continuing Education
prIME Oncology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
prIME Oncology designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
This activity is provided by prIME Oncology.
Disclosure Information
Method of Participation
There are no fees for participating in and receiving CME credit for this activity. In order to receive credit, participants must successfully complete the online activity evaluation. Your participation in this CME activity will be recorded in prIME Oncology's database. However, upon request, your CME credit certificate will be emailed to you. Technical requirements may be found under the Terms of Use.
Disclosure of Relevant Financial Relationships
prIME Oncology assesses relevant financial relationships with its instructors, planners, managers, and other individuals who are in a position to control the content of CME activities. Any potential conflicts of interest that are identified are thoroughly vetted by prIME Oncology for fairness, balance, and scientific objectivity of data, as well as patient care recommendations. prIME Oncology is committed to providing its learners with high-quality CME activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial entity.
The faculty reported the following financial relationships or relationships to products or devices they or their spouses/life partners have with commercial interest related to the content of this activity:
Dr Ascierto has disclosed that he has a consultant/advisory role for Amgen, AstraZeneca, Array BioPharma, Bristol-Myers Squibb, Genmab, Idera, Incyte, MedImmune, Merck Serono, Merck Sharp & Dohme, Newlink Genetics, Novartis, Pierre-Fabre, Roche-Genentech, Syndax, Sanofi, and Sun Pharma. He also disclosed research funding from Array, Bristol-Myers Squibb, Merck Sharpe & Dohme, and Roche-Genentech. He has agreed to disclose any unlabeled/unapproved uses of drugs or products referenced in his presentation.
Dr Blank has disclosed that he received consulting fees from Bristol-Myers Squibb, Genmab, GSK, Lilly, MSD, Novartis, Pfizer, and Roche. He also disclosed independent contracting for BMS, Novartis and Nanostring. He has agreed to disclose any unlabeled/unapproved uses of drugs or products referenced in his presentation.
Dr Hamid has disclosed that he has received consulting fees from Amgen, BMS, Merck, Novartis, and Roche Genentech. He also received honoraria for promotional speaker's bureaus from Amgen, Array Biopharma, BMS, Novartis, and Roche Genentech. He also disclosed independent contracting for his institution for AstraZeneca, Bristol-Myers Squibb, Celldex, Immunocore, Incyte, MedImmune, Merck, Merck Serano, Novartis, Pfizer, Rinat, and Roche Genentech. Furthermore, he disclosed membership on advisory committees or review panels for Amgen, BMS, Merck, Novartis, and Roche Genentech. He has been speaking and teaching for Amgen, Array Biopharma, BMS, Novartis, and Roche Genentech. He has agreed to disclose any unlabeled/unapproved uses of drugs or products referenced in his presentation.
Dr Lebbé has disclosed that she has been in adboards for Aventis, BMS, Merck, MSD, Novartis, and Roche. Furthermore, she has been speaking and teaching for BMS. She has agreed to disclose any unlabeled/unapproved uses of drugs or products referenced in her presentation.
Dr Ribas has disclosed board membership with PACT Pharma. He received consulting fees from Amgen. BMS, Chugai, Genentech, Merck, MSD, Novartis, and Roche. Furthermore, he disclosed ownership interest in Advaxis, Arcus, Bioncothech, Compugen, CytomX, Five Prime, FLX-Bio, ImaginAb, Isoplexis, Kite-Gilead, Merus, Rgenix, Lutris, PACT Pharma, and Tang Therapeutics. He has agreed to disclose any unlabeled/unapproved uses of drugs or products referenced in his presentation.
The employees of prIME Oncology have disclosed:
- Angela K. Zimmermann, PhD (scientific content reviewer/planner) – no relevant financial relationships
- Jessica Mastrodomenico, MPH (editorial content reviewer) – no relevant financial relationships
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients' conditions and possible contraindications or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.
Disclosure Regarding Unlabeled Use
This activity may contain discussion of published and/or investigational uses of agents that are not indicated by the US Food and Drug Administration or European Medicines Agency. Please refer to the official prescribing information for each product discussed for discussions of approved indications, contraindications, and warnings.


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The high patient doses required for biologic therapeutics present significant drug-delivery challenges. A large proportion of these drugs are currently injected using intravenous infusion in the hospital, or increasingly in the home. [1] Materials from Covestro are used in applications critical to the intravenous infusion process as well as in injectable drug delivery devices that enable drug delivery in the home setting.
Did you know?
The personalized medicines era is shifting the focus of pharmaceutical development and manufacturing activities from small molecules to biologic drug products.
[1] PharmTech.
For more information, email us: email@example.com.
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Here you can see step by step how to do a honeycomb-ball made out of plastic bags. Honeycombs balls are usually made out of paper and there are a lot of really good tutorials out there: Read More
All posts tagged "Basteln"
Musical instrument workshop in the Bundeskanzleramt | 29-30.8.15
In August 2015 Kunst-Stoffe was invited to give an upcycling workshop for the "Tag der offenen Tür" in the Bundeskanzleramt. In the workshop we built musical instruments out of waste material brought from the Kunst-Stoffe Lager.
We also built a smaller stage with a microphone, two loudspeakers and D.I.Y amplifiers, where the kids could play with their new, self-made instruments.


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Champlain College Saint-Lambert will become a smoke and tobacco-free campus for all for employees, students, and visitors effective July 1st 2017.
The use of all tobacco products is prohibited on campus properties, both indoor and outdoor, of the College including all buildings and grounds owned by the College. This policy applies to the parking lot as well as the front and side walkways. Tobacco is defined as any type of tobacco product including, but not limited to cigarettes, cigars, cigarillos, electronic cigarettes, smokeless or spit tobacco or snuff.
For those who are interested in stopping their use of tobacco products please contact Health Services (students) or the local HR department (faculty and staff) for a list of resources and programs.


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Fund management group Henderson has announced that it has reached an agreement for the acquisition of beleaguered asset management firm Gartmore, for an estimated £355 million.
Following the announcement, shares in the group were up more than 11% at 154p, as the company said the acquisition would lead to a "significant enhancement" of its presence, with combined assets under management of £78 billion. This will make Henderson the sixth largest fund management firm in the UK retail space.
The directors of Gartmore said they consider the terms of the acquisition to be fair and reasonable and would unanimously recommend that shareholders vote in favour of the acquisition.
So far 12 Gartmore fund managers have said they will remain with the combined group, including Charlie Awdry and Chris Palmer from the emerging markets team and John Bennett from the European equities team.
Henderson said it was still working to secure the support of further Gartmore fund managers and added that the 12 it had already secured represented 84% of Gartmore's assets under management.
Completion of the acquisition will take place within the next three months, subject to Henderson and Gartmore shareholder and regulatory approval.
Andrew Formica, chief executive of Henderson Group, said: "The acquisition of Gartmore is a great opportunity for Henderson. Gartmore has a highly complementary strategy and stable of products to that of Henderson. Its recent travails should not overshadow the fact that Gartmore is one of the best known managers in UK fund management and its assets are performing well."
At the tail end of last year Gartmore went through a tumultuous time when its star fund manager Roger Guy and its chief investment officer Dominic Rossi announced their departure. Since it floated in 2009 at 220p, shares in Gartmore have more than halved to 100p.


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I was surprised by how much I enjoyed reading this book. It looked okay, but as I got into it, I found more and more excellent food for thought. It's a lot about calling, endeavors, discernment, etc.
But, one of the things I liked the best about the book were the author's life anecdotes. Whether he was writing of his past, present, or simply about the coffee business, he kept it very interesting, yet low key.
I wouldn't hesitate to recommend this book and will be putting it in my church library as a resource.


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After that first trout I was alone in there. But I didn'tknow it until later.Richard Brautigan
FameRank: 4
"Richard Gary Brautigan" was an American novelist, poet, and short story writer. His work often employs black comedy, parody, and satire. He is best known for his 1967 novel Trout Fishing in America.If you enjoy these quotes, be sure to check out other famous writers! More Richard Brautigan on Wikipedia.


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Justin + Sarah | Charlotte, NC
Justin and Sarah's cozy yet elegant wedding day had a natural feel with its supremely lush floral designs and panoramic oceanfront ceremony. From the bride's bouquet to the enchanting vines hanging overhead, Bells & Whistles pulled out all the stops. The couple toasted to their new life together as husband and wife at a place they both dearly love with the help The Proper Setting to coordinate from afar. We're thrilled that their vision came together perfectly with the help of an amazing team of OBWA vendors in this Outer Banks Weddings Magazine 2017 Real Wedding feature!
Photographer | Natalie Heim Photography
Reception Site | First Colony Inn
Coordinator | The Proper Setting
Floral & Décor | Bells & Whistles
Officiant | I Do OBX Weddings
Hair & Makeup | Hairoics Spa & Salon
Musician | Outer Banks Wedding Entertainment
Caterer | Café Lachine
Equipment Rentals | Ocean Atlantic Event Rentals // I Do OBX Chairs
Why the chose to wed on the Outer Banks: Soon after coming home to Charlotte, we decided the Outer Banks was where we wanted to get married. I grew up in New Jersey and my family visited the Outer Banks every summer for vacation. Justin grew up in Virginia and visited often with his family as well, so we both felt it was a great place to join our families.
The inspiration behind their wedding: We visited again in September 2015 with my parents and picked the venue. We loved how cozy the First Colony Inn was, and could both envision our friends and family all spending the weekend together celebrating there. After the when and where were picked, everything that followed was really a collaborative effort by Justin and I and our families. My mom had a beautiful vision in her head of a very natural but elegant décor, and all of the vendors we worked with really helped to bring that vision to reality.
To view Justin and Sarah's real wedding, endless Outer Banks wedding inspiration, and for our in-demand vendor directory, request a complimentary copy of Outer Banks Weddings Magazine 2017.


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The Great ShakeOut
Marysville School District
Thursday, October 18, 2018
Today, at 10:19 am PST, the Great ShakeOut was held across the Nation. Some schools in the District also participated. Our schools regularly hold drills for fire, earthquake, and evacuation. To learn more about the Great ShakeOut and earthquake preparedness, go to https://www.shakeout.org/index...


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Also found in: Dictionary, Thesaurus, Encyclopedia.
sequela[sĕ-kwel´ah] (pl. seque´lae) (L.)
a morbid condition following or occurring as a consequence of another condition or event.
postpolio sequela (postpoliomyelitis sequela) postpoliomyelitis syndrome.
sequelaeClinical medicine The consequences of a particular condition or therapeutic intervention
sequela(sē-kwē′lă) plural.sequelae [L., sequel]
A condition following and resulting from a disease.


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Chris Burke of SI.com predicted both the first and second rounds of the upcoming NFL Draft in his latest mock (Feb. 11).
Burke has the Jets selecting Ohio State OLB Darron Lee in the first round (20th overall).
In the second round (51st overall), Burke predicts the Jets will draft Michigan State DE/OLB Shilique Calhoun.
Brian Bassett, theJetsBlog.com Facebook | Twitter | Instagram | TJB Posts
Considering that the Broncos just willed their tepid offense to a Super Bowl victory with the best pass rushing outside linebacker duo in the league, it will be popular for analysts to pick OLB help early for the Jets. After watching Ben Roethlisberger, Tom Brady and then Cam Newton get knocked to the turf, many will see pass-rush as the new NFL salvation. Remember when everyone was looking for athletic defensive ends just like the Giants? Good times.
That doesn't make grabbing an OLB early the wrong pick for the Jets, as they could desperately use some help at rushing the passer. But to chase the trend is never a smart move.
Also, consider that the Jets have one of the best defensive lines in football with Leonard Williams, Sheldon Richardson and Muhammad Wilkerson. While grabbing a first rounder at linebacker would be a nice feather in the cap of the defense, I think the Jets will have to consider how they marshall their resources moving forward. What can a first rounder provide that a second rounder can't when paired with that line?
The Jets will take whoever the best player on the board is, but if given a choice, I'd love to see them shore up the offensive line first.


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Xactware Publishes April 2015 Price List
The April 2015 price list updates for the nine regional pricing databases in the United Kingdom and the two for the Republic of Ireland are now available for download.
As a provider of estimating and management solutions for the property insurance, refurbishment, and restoration industries, Xactware publishes quarterly price list updates to give insurance professionals and contractors access to current local rates for thousands of building and reinstatement line items. Xactware gathers cost information contained in these schedules from live estimates as they are processed as well as from frequent surveys with labour and material suppliers.
Changes to the April price list
For the April 2015 price list publication, Xactware has altered the behavior for labour minimums to focus on trade rather than categories. New line items have been added for single membrane roof finishes, door framing, and masonry wall chasing. The quarterly price list publications include 32 new line items and 95 modified line items.
Customers can view specific changes to the price lists by logging in to the eService Centre.
Local market conditions
Xactware makes every effort to ensure pricing information contained in the most recent update represents market costs at the time of publication. Since actual market prices can vary and may change rapidly, and since many factors can affect the cost of a project (including — but not limited to — labour, plant, and material costs as well as the rates and application of VAT), we strongly recommend customers monitor their local markets for any such changes and adjust their estimate pricing as deemed appropriate.
Pricing feedback
Please report any price changes to Xactware as soon as possible. We will then adjust any information that can be independently verified for inclusion in future price list publications. You can submit pricing feedback online or via email to Xactware's pricing team at:
- firstname.lastname@example.com for U.K. inquires
- firstname.lastname@example.com for Ireland inquires
Downloading a price list in Xactimate
If you are a registered Xactimate user, you can download price lists in four steps:
- In Xactimate, select Price List tab in the main dashboard,
- Select Request Price List(s) on the menu bar.
- From the "Request Price List" window, enter the country, region, and area for the price list you would like to download.
- After making your selections, select Download.


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|Eastern Mojave Vegetation
|Motte Family Monument
If you have a question or a comment about this photograph you may write to me at: firstname.lastname@example.com I sometimes post interesting questions in my FAQ, but I never disclose your full name or address.
Photograph taken March 22, 2008.
Article records that use this photograph:
Other photos about Geography - California or Miscellaneous Pastoral Scenes.
Date and time this page was prepared: 6/19/2020 5:32:08 PM


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If expired blogs have backlinks pointing to them you do not require a tier 2 in your ranking system. This makes the ranking process a whole lot easier and faster.
I will register the expired Tumblr and WordPress blogs for you, which I will pass onto you when the order is complete.
The blogs are free, there is no hosting to pay for, this is why they are so much more sought after than PBN backlinks.
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The United States is not the only country to celebrate Valentine's day!
As February 14 comes around the corner, many thoughts turn to love, romance, and special celebrations. In Japan, the feelings are similar. Valentine's day is celebrated all over the world, and it's no different in the Land of the Rising Sun.
For the Japanese, Valentine's day is for women to show appreciation for all the men in their life, not just lovers. For male friends, co-workers, and bosses, women give chocolates called "giri-choco". This means "obligation chocolate" and has no romantic feeling behind them.
These simple gifts are usually store-bought chocolates or other small gifts. As you could probably guess, this can sometimes cause stress and pressure, which is probably what lead to the term "cho-giri-choco," meaning "very obligatory chocolate."
That's for the guy who really gets on your nerves!
A More Popular Valentine's Day Tradition
A more recent type of this chocolate, called "tomo-choco," is becoming quite popular with schoolgirls. This is a simple gift for female friends, and is a nice way to include everyone.
The other type of chocolate, "honmei-choco," is for a boyfriend, love-interest, or husband. These chocolates and baked goods are usually handmade to show how much the woman really cares.
Around this time of year, Japanese stores are packed with baking supplies, decorations, wrapping papers, and all sorts of other goodies to make your gifts extra special. Often, the amount of effort and love put into "honmei-choco" is a symbol for how much a woman cares for and loves the recipient.
Women get a special day too!
That may seem a bit unfair, but the women have a special day, too! One month later, on March 14, men give chocolates and gifts to the women in their lives. The chocolate is often white, giving this holiday the name "White Day." The men give women chocolates, flowers, jewelry, and other small gifts.
Just like the Valentine's Day Gifts, the White Day gifts have more meaning if more effort and love are put into them. When giving a "giri-choco" gift on White Day," it is usually about the same value as the one they received a month prior.
However, White Day "honmei-choco" is a bit more elaborate. Some men practice the idea of "sanbai gaeshi," which means "three times return." For this, the men give their girlfriend, love interest, or wife a gift with a value triple the one they gave him.
Cultures all over the world celebrate this holiday a little differently. What do you do for this special day?


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Ladytron – Roxy Music
You've got me girl on the run around, run around got me all around town
June 1973, Lewes Priory 5th form are doing their O Levels – for some reason I'm only doing six – English Literature, English Language, Geography, History, a split course Biology/Chemistry and Latin. I know. Latin. I hated it. The teacher was a permanently drunk Welshman called Dai Jones and I learned nothing and failed the exam with a 9. The lowest possible score. I'd already done French, Art and Maths in the 4th year, and the following year in the Lower Sixth I would take Geology which was my favourite subject of all time. I very nearly did a degree in Geology because I loved it so, particularly the section-maps going underground to reveal the layered rocks beneath, which you had to draw only from surface evidence – wow that was cool. I still love those maps. Had I followed that particular nose I would have been lost to all but the oil companies I suspect, perhaps the main reason, in the end, that I decided to do Law instead. But in the 5th year all these considerations were way off. There was a mini-cultural explosion in mid-June when the LP Roxy Music was released and kids started carrying the distinctive blue and pink cover with Kari-Ann Muller giving us her pin-up flex around the classroom. Derek Sherwin certainly had a copy !
16-year old boys with pin-up LP covers ! Further examination revealed a music that none of us had even imagined before, let alone heard. This was a musical box of chocolates with every shape, flavour and colour and we became obsessed, none more so than me. I couldn't get enough of this record and played it to death over the summer of '73, with the result that my younger brother Paul, turning 14, became an even bigger Roxy Music fanatic than me – almost an impossible feat! Deep inside the carefully-designed sleeve were more delights, pin-ups of the band members who appeared to have beamed down from an outer space glamour convention, the lot "designed" by Anthony Price.
Well Graham Simpson on bass looks pretty Andy-Williams-normal. But Andy Mackay became my new saxophone guru although he also played the oboe and could do things that I couldn't even contemplate on the saxophone, nevertheless I did play along with Ladytron from time to time, a moment that sums up everything about Roxy for me at that time – Mackay's sax and Phil Manzanera's electric guitar playing a harmonic riff together while a mental piano plinks and plonks some kind of rhythm around it under an odd electronic bubbling from weirdo Brian Eno (bottom middle in the pic above), making it all sound sci-fi, and still everything, and I mean everything is rooted to the rock-solid rock-steady drums of Paul Thompson (with a tiger on his shoulder above). And Ferry, above all else, Bryan Ferry's vocals, mannered, exquisite, English, haunted, pleading, romantic. I worshipped the man. This feeling grew over the ensuing three years as further LPs came out, costumes were worn, lyrics were caressed. But for now all I had to go on was this picture, these strange but compelling gentlemen from the planet Rock which was in this incarnation planet Roxy. Some of them were wearing make-up! They were clearly obsessed with style as much as music. With glamour more than chasing a hippie dream. That summer my first eyeshadow was bought, and worn, although not around the council estate where I lived. I knew that young men were a little sensitive about these matters.
When I listen to the LP today it still has the same effect on me as it did when I was a 16-year old boy. It thrills me to the core with it's daring clashes of style, it's thunderous drumming which anchors every splash of electro-wierdness, the oboe, the guitar, the lyrics about Humphrey Bogart, about World War Two, about Brief Encounter, but above all else a huge confident new sound, rooted in rock'n'roll but re-made, re-modelled for the future. It became my musical badge of honour and remains my favourite of their LPs. I have them all of course, and all of Ferry's solo output and Brian Eno's. This LP is a pinnacle of art-rock, and they would never return there. I've seen them live too, and met the man, but that's for a later conversation. For now, just listen to those castanets, and the sheer thrill of the beat doubling up for the instrumental drive-by. Sensational music.


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We always hear that Google's search algorithm automatically figures out where websites should rank for keyword searches and that we can't predict it. However, Google has given us insights throughout the years about what's essential in improving our ranking in their algorithms. At the highest priority of the list: quality. Google needs to rank sites that satisfy the requirements of searchers; sites that give a positive experience. All things considered, that is how Google maintains its position as the most used search engine. If a site needs to rank highly, it should be providing its users with a good experience. Seems straightforward, right? And yet there are various sites that aren't exactly hitting the mark. Here are 3 website design mistakes that harm SEO efforts.
To start with, not all website advertising is bad. Google understands that website owners need to make a profit off their website. However, ads should be background noise, not the main thing users see on the website. Website ads are divided into two categories: obvious and hidden. Obvious advertisements are terrible for clear reasons. They pop up in front of website content or take up prominent space on the page, compelling clients to look down to locate the content they're searching for. In addition to being simply annoying, they can cause users to back off the website. Hidden ads are advertisements that are tricky in nature, similar to affiliate links placed in the middle of content that isn't designated as sponsored links. These types of ads are much more effective at not only increasing the website owners advertising profit, but also ensuring the website content reaches the user.
Usability Issues
It should be simple for website visitors to explore the website, regardless of what device or browser they are utilizing. Today, all websites should have a responsive design (site automatically adapts to screen size) with developers performing ease of use testing across all major platforms. SEO work is wasted if it lives on a website that isn't completely accessible or easy to see/utilize. The navigation should be worked in a way that makes it simple for visitors to discover what they are searching for within a couple of clicks. Slow page load time is another SEO-killer. Google won't rank websites that take a long time to load since those websites have a bad user experience.
Bad Content
At its foundation, SEO is truly about content quality. Engaging content produces inbound connections that tell web crawlers that the page offers something of value and thereby rewarding the page with a high search rank for applicable keywords. If a website doesn't have rich content, it won't create user interest, and won't rank well for competitive keywords. A website is one of the most essential touchpoints for a company's brand and if there is poor content it will reflect poorly on the overall brand.
These are the most widely recognized mistakes that we see throughout websites. Search engine optimization requires significant amounts of time, effort, and resources. If you are putting resources into running an SEO campaign, the initial step is to guarantee that you have a website that is deserving and will benefit from the campaign.