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Posts Tagged 'federal research funding'
Science Policy Around the Web February 13th, 2020
By Thomas Dannenhoffer-lafage PhD
Trump Proposes a Cut in Research Spending, but a Boost for AI
On Monday, February 10th, President Trump released his budget request for the 2021 fiscal year. The proposed budget calls for cuts in research across almost all federal agencies, with the notable exception of NASA. While the total budget of most federal agencies is planned to be cut, the budget also requests that a larger amount of the remaining money be directed towards research in artificial intelligence (AI) and quantum computing. The call for more research funding in AI has been recommended in reports and requested in legislation. The budget would call for an overall 9% percent reduction in research spending and will likely be modified by Congress, who usually oppose cuts to research spending.
The pushes for more research funding in the fields of AI and quantum computing were prioritized because the administration claims that these technologies "underpin the Industries of the Future." The technologies of AI and quantum computing have also received substantial investment from China. Insiders have claimed that the president has acted responsibly, as these areas have been identified as areas of great competition. Dario Gil has also claimed that the investment in AI will accelerate discovery and that it is "going to permeate every sector of the economy and national defense."
However, others have pointed out that the new budget may actually harm the development of new technologies by limiting the scope and funding of basic research. As Martijn Rasser points out: "[w]e don't know where the next breakthrough will come from." Others worry that an exclusive focus on AI research may actually hamper overall progresses of the field since inspiration for new ideas can come from different fields. Subbarao Kambhampati claims that "[n]euroscience will be really relevant to AI in over the longer term [sic]." This is exemplified by Neural Networks, an important component of many AI technologies, whose creation was inspired by the connections of neurons in brains.
(Will Knight, Wired)
Science Policy Around the Web – May 31st, 2019
By: Silvia Preite, Ph.D.
Common drink and food sweetener – High-Fructose Corn Syrup – accelerates colon cancer growth in mouse models: what about in humans?
Increased consumption of sugar-sweetened drinks has been associated with higher risk of obesity and intestinal cancers. However, whether sugar directly contributes to tumor development, independently from obesity, is less clear. A common sweetner of sodas, fruit-flavored drinks and processed foods is high-fructose corn syrup (HFCS). A recent study published in Science revealed that consumption of HFCS accelerated colon cancers in predisposed mice bearing a mutation in a tumor-suppressor gene commonly found in human colorectal colon cancers. Strikingly, the human diet equivalent amount of HFCS required to see such effects in mice corresponds to 12 ounces of a sweetened drink – one can of soda per day!
Mice fed with HFCS did not become obese or developed metabolic syndrome, however, developed larger and more advanced tumors, compared to water-treated animals. Mechanistically, HFCS leads to increased levels of fructose and glucose in the intestinal lumen and serum, that can be transported and utilized inside the tumor to generate energy and support its growth. The identification of these events opens new possibilities for the development of therapeutic strategies aimed at controlling tumor growth; in particular, targeting of fructose metabolism may selectively slow tumor progression without affecting survival of normal cells.
Further studies are needed to assess if similar tumorigenic mechanisms take place in humans. Moreover, whether prolonged and extensive consumption of HFCS has a greater detrimental effect on human health compared to other types of sugar remains to be determined. Regardless, this study could contribute to increase public awareness about the potential deleterious effects on physical health and tumor development due to sweetened drinks and processed food whose comsumption is globally rising.
(Source: Goncalves et al., Science, 2019)
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Science Policy Around the Web – May 14th, 2019
By: Mary Weston, Ph.D.
Rural areas drive increases in global obesity
While past studies have found that the increase in global obesity is largely driven by urban regions, a newly published paper argues that this rise is actually being led by those in rural areas.
Global increases in BMI (body mass index) have been observed for decades, but no one had evaluated differences in urban and rural regions on a large-scale across many countries. The new Nature study evaluated BMI values in 200 countries from 1985-2017, finding that rural areas are responsible for more than 55% of the global rise in the average BMI and more than 80% of the rise in some low- and middle-income countries (LMICs).
Previous theories argued that urbanization caused rising BMI largely because of the availability of cheap, ultra-processed foods, a lifestyle that provides more transportation options, and greater access to non-physical leisure activities (smartphones, cable television). In contrast, rural areas were thought more likely to consume more local produce, have less access to ultra-processed and packaged food, and participate in high energy expending activities. However, rural areas, even in LMICs, have now begun to resemble urban areas because of access to ultra-processed foods and cheap mechanized devices that reduce transport and farming energy expenditure.
Obesity results in higher health care costs, lower life expectancy, and reduced quality of life. Thus, prevention strategies are vital but currently, most preventative measures are targeted towards urban areas. Given this new data, funding priorities and strategies need to adjust to address this growing issue.
(Barry M. Popkin, Nature)
After outcry, USDA will no longer require scientists to label research as 'preliminary'
After protests, the US Department of Agriculture (USDA) has stopped requiring their staff scientists to label all published peer-reviewed research as "preliminary." Released last week, the revised USDA guidelines now require the following language when disclaimers are necessary: "The findings and conclusions in this [publication/presentation/blog/report] are those of the author(s) and should not be construed to represent any official USDA or U.S. Government determination or policy." Not all publications will be obliged to contain this statement.
Previous USDA guidelines, implemented last July, required publications to carry the label: "The findings and conclusions in this preliminary publication have not been formally disseminated by the [USDA] and should not be construed to represent any agency determination or policy." This disclaimer caused concern over claims that it was confusing and possibly misleading. Scientific publications are peer-reviewed (evaluated by professionals in the field for quality and accuracy) and considered completed work, not preliminary. Some among the scientific community feared the disclaimer might reduce the impact of the published research conclusions or be used to diminish findings that conflict with views of the current administration.
While reaction towards the disclaimer change has been generally positive, some non-USDA researchers are still concerned that the latest guidelines have the potential to jeopardize scientific integrity. The new guidelines say that the USDA can request "corrections" or "changes" to research papers if they pertain to a "prominent issue," a significant scientific advancement, or could influence trade/policy decisions. Rebecca Boehm, an economist at the Union of Concerned Scientists, stated that "removing 'preliminary' from the disclaimer is a step in the right direction, but there still may be unnecessary obstacles preventing agency researchers from publishing their work in peer-reviewed journals."
(Ben Guarino, Washington Post)
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Science Policy Around the Web – June 13, 2017
By: Nivedita Sengupta, PhD
Stem Cell Therapy
Texas on Track to Become First State to Explicitly Back Stem Cell Therapies
On 30th May, Texas passed a bill authorizing unapproved stem cell therapies, making Texas the first state to openly recognize experimental treatments. The bill will make the use of unapproved stem cell therapies legal for patients and is currently awaiting the approval of Governor Greg Abbott, who already supports the measure. Experimental stem cell therapies for terminal and chronic conditions have struggled for years to gain support without much success. Until now, no state has provided legal validation for these kind of therapies and the current stem cell procedures are mostly done under strict regulations.
Amendments were added to the bill, which require that the treatments be delivered by doctors with the approval of an institutional review board, which deals with human research. It will also add another amendment that will allow patients to have authority to sue in case the treatments go wrong. Many scientists and advocates opposed the measure stating that unapproved stem cell therapies can be harmful rather than beneficial. They state that though the amendments add protection to the patients, there are a few aspects of the bill that make them uncomfortable. Two other bills focused on patient access to experimental therapies, also known as "right-to-try" policies, failed to pass in the Texas Senate. (Andrew Joseph, STATNews)
Research Funding
NIH Scraps Plans for Cap on Research Grants
US National Institutes of Health (NIH) decided to drop the controversial proposal of capping the number of grants that an investigator can have at a time. The initial capping attempt was suggested to gather funds for younger researchers by NIH in May. The proposal was based on studies that suggested that a lab's productivity decreases once it holds too many grants. Younger scientists often face more difficulties in obtaining NIH RO1 grants compared to their older more experienced colleagues. As a result, many researchers applauded the NIH's effort to provide more funding for younger scientists. Yet the capping proposal received major adverse response from the scientific community stating that the NIH's interpretation of the productivity study data does not apply to all labs, especially to the collaborative lab groups with four or five R01s that are more productive than labs with only one. Researchers also complained that the proposed point-based scoring system will also make collaborations difficult thus hampering productivity in the long run.
NIH director Dr. Francis Collins stated that the original idea was still a work in progress and NIH is going to put a hold on it. Instead of the cap, on 8th June, NIH announced the creation of the special fund, the Next Generation Researchers Initiative (NGRI), starting with US$210 for funding young researchers. The initiative will focus on investigators with less than 10 years of experience as NIH- funded principal investigators, and on high score grant proposals that were rejected because of lack of money. The initiative will grow up to $1.1 billion over the next five years. According to NIH principal deputy director Larry Tabak, NIH will immediately start creating an inventory of investigators who meet these criteria and expects that this approach will allow more than 2,000 additional R01 grants to be funded to younger scientists compared to the cap-based plan, which would have supported only 1600 awards. Nonetheless, the current proposal is still going to generate controversy as it will affect the older researchers because of NIH's diversion of funding. (Sara Reardon, Nature News)
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Science Policy Around the Web – May 24, 2017
By: Joel Adu-Brimpong, BS
Scientific Publishing
The beauty of the scientific enterprise is that it is, eventually, self-correcting. Thus, occasionally, a scientific paper may be retracted from a journal based on new revelations or due to reports of ethical breaches. Tumor Biology, a peer-reviewed, open access journal disseminating experimental and clinical cancer research, however, seems to have set a record for the number of retracted papers at once. In a single notice, in April, Tumor Biology retracted 107 articles; yes, one hundred and seven!
Springer, the former publisher of Tumor Biology, reported that the retracted papers were due to a compromised peer review process. Like other journals, Tumor Biology allows the submission of preferred reviewer information (name and email address) when submitting a manuscript. In the case of the retracted papers, "the reviewers were either made up, or had the names of real scientists but false email addresses." Unsurprisingly, the manuscripts sent to the fake reviewers consistently received positive reviews, bolstering the likelihood of publication.
Springer, of course, is not the first and only major publisher to uncover issues in its peer-review process leading to mass retractions. A 2016 paper reveals similar issues from other major publishers including SAGE, BioMed Central and Elsevier. These breaches are particularly worrisome as some of the retracted manuscripts date back to the beginning of the decade. This means that studies floating around in other journals may have built on knowledge reported by the retracted studies. As if this was not enough, Springer has also come under scrutiny for individuals listed on Tumor Biology's editorial board, several of whom appear to have no association with the journal and/or in at least one case, have been deceased for several years.
These discoveries are particularly disturbing and are percolating at a time when biomedical research spending is increasingly being scrutinized. Richard Harris, the award-winning NPR journalist, in his recent book Rigor Mortis: How Sloppy Science Creates Worthless Cures, Crushes Hope, and Wastes Billions (2017), highlights major areas in biomedical research that produce wastes, such as studies that may incite researchers, and even whole fields, to follow a phantom lead. In the meantime, it does appear that journals are taking measures to ensure that these breaches are minimized, if not prevented entirely. (Hinnerk Feldwisch-Drentrup, ScienceInsider)
Research Funding
Fighting On All Fronts: Republican Senators Advocate for DOE's Research Funding
Republican senators are, again, urging President Trump to rethink potential budget cuts to research programs; this time to the Department of Energy (DOE). On Thursday, May 18, 2017, six top senate republicans, including well-known congresspersons Lamar Alexander (R-TN), Lindsey Graham (R-SC) and Lisa Murkowski (R-AK), drafted a letter to the President reminding him of the importance of government-sponsored research. In the letter, they re-echo, "Government-sponsored research is one of the most important investments our country can make to encourage innovation, unleash our free enterprise system to create good-paying jobs, and ensure American competitiveness in a global economy." They go on, "It's hard to think of an important technological advancement since World War II that has not involved at least some form of government-sponsored research."
If it seems like we've been down this road before, it's because we have. Earlier this year, Rep. Tom Cole (R-OK), on the House Appropriations and Budget Committee, and his colleagues signaled disagreement with proposed budget cuts to the NIH and CDC in President Trump's fiscal blueprint. The Republican congressman reiterated the importance of agencies like the NIH and CDC in conducting crucial biomedical research and leading public health efforts that protect Americans from diseases. The strong commitment to advancing biomedical research and the health of the American people led to an omnibus agreement that repudiated President Trumps proposed cuts, increasing NIH funding by $2 billion for the 2017 cycle.
The letter by Senator Alexander and colleagues was drafted following reports suggesting that the DOE's Office of Energy Efficiency and Renewable Energy could face a reduction in funding of up to 70 percent for the 2018 fiscal cycle. In a separate follow-up analysis, Democrats on the Joint Economic Committee reported on the growth and importance of clean energy jobs and its contribution to the economy. Cuts to the DOE's research programs could have profound impact on not only millions of jobs but also America's ability to stay competitive in the global economy as it shifts towards renewable energy and resources. (Geof Koss, ScienceInsider)
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Science Policy Around the Web – May 5, 2017
By: Thaddeus Davenport, PhD
Healthcare Policy
House Passes Bill to Repeal and Replace the Affordable Care Act
Thomas Kaplan and Robert Pear reported for the New York Times yesterday that Republicans in the US House of Representatives voted to pass a bill that would undo a number of central elements of the Affordable Care Act. Only six weeks ago, House Republicans failed to gather enough support to even vote on the first version of this bill, which was predicted to eliminate insurance coverage for twenty-four million Americans over the next decade. Since that time, Republican lawmakers have modified the so-called American Health Care Act (AHCA) bill to appeal to the more conservative members of the House – including provisions that would limit federal support of the Medicaid program, allow states to opt out of requiring that insurance cover services like maternity and emergency care, and also enable states to apply for waivers that would let insurance companies charge higher premiums for some individuals with pre-existing conditions. Like the first version, the bill that passed the House on Thursday does away with the 'individual mandate', which imposes a tax on people who can afford to buy insurance but do not – an aspect of the Affordable Care Act that was relatively unpopular but critical to ensure sustainability of the insurance markets. It also replaces government-subsidized insurance plans with tax credits between $2,000 and $4,000, depending on age. Other provisions in the bill would stop federal funding to Planned Parenthood for one year as well as eliminate taxes on high-income individuals, insurance companies, and pharmaceutical companies that helped to fund the Affordable Care Act. Yesterday, 217 Republicans voted in favor of the revised AHCA bill that will certainly not provide healthcare insurance for everyone, without waiting for a non-partisan Congressional Budget Office analysis of the bill's impact on the federal deficit or on the American people. These representatives' haste reveals that they care little about how the AHCA will actually affect their constituents' lives, and Democrats are counting on voters remembering this in upcoming elections. (Thomas Kaplan and Robert Pear, The New York Times)
Science Funding
NIH Funding Changes to Support More Early Career Investigators
The NIH budget has gradually declined over the last fourteen years, from $40 billion in 2003 to about $32 billion in 2017. Given that a proposed budget from the Trump administration for fiscal year 2018 would further cut funding for NIH by $5.8 billion, it is unlikely that funding for the NIH will increase dramatically in the coming years. To address these budget limitations, and in an attempt to do more with less, Jocelyn Kaiser reported for ScienceInsider this week that the National Institutes of Health will impose a cap on the number of grants awarded to investigators. In an open letter announcing the decision, NIH director, Francis Collins, writes that 40% of NIH funding is concentrated in the hands of 10% of NIH-funded investigators. He notes that this is not inherently problematic, except that many studies indicate that there are diminishing scientific returns on each additional dollar that is granted to any individual investigator. Under the new guidelines, investigators will be limited to a maximum of three R01-equivalent grants in order to support approximately 1,600 more grants to early career and mid-level researchers, who have been particularly affected by the declining NIH budget. While it is difficult to quantify scientific impact, the NIH decision is admirable for its intent to support diversity and efficiency in funding research. (Jocelyn Kaiser, ScienceInsider)
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Science Policy Around the Web – April 4, 2017
By: James Taylor, PhD
Research Funding
NIH Research Grants Yield Economic Windfall
Assessing the social and economic benefits of basic research – research conducted with no clear medical or financial goal in mind – has is often tricky with the former being philosophical in nature whilst the later sometimes coming years later from unexpected angles. A classic example of this process is the polymerase chain reaction (PCR), which was built on basic research on DNA replication in bacteria from hot springs published years before its invention. Critics of publicly funded research often take studies out of context in order to ridicule them, such as Sarah Palin's infamous "fruit flies" comment.
A recent analysis of the economic effects of the National Institutes of Health (NIH) funding has shone light on the economic benefits of basic research. Danielle Li and colleagues found that although 8.4% of NIH grants between 1980 and 2007 led directly to patents, 30.8% produced a scientific article which was later cited in a commercial patent for a drug, device or other medical technology. This demonstrates an enormous but indirect benefit of publically funded research. Furthermore, when the studies were broken down into basic or applied (research with a stated medical or commercial goal) they found no difference between the two in terms of how likely they were to be cited in a patent. This should give funding bodies pause for thought, as it calls into question their growing emphasis on applied research.
Taking into account the indirect effects of NIH funded research, the authors estimate that every $1 in NIH funding returns $1.40 in drug sales. This report is timely with proposed budget cuts for science funding looming large in the horizon, and exposes such cuts as sheer economic folly. (Elie Dolgin, Nature News)
HIV Infections are Spiking Among Young Gay Chinese
Recent surveys of HIV infections in China have shown a worrying spike in HIV infections among young gay and bisexual men, and have sparked the implementation of a broad 5-year plan to raise awareness and boost research into new treatments by the country's ruling State Council. In the early 2000s, HIV infections were most prevalent amongst drug users in China, but there has been a steady decrease in prevalence amongst this group. The increase in HIV infections amongst men who have sex with men (MSM) has bucked this trend, and instead has been rising at an alarming rate. The cause of this increase remains unknown, with researchers at the National Health and Family Planning Commission in Beijing and China Medical University in Shenyang rather hopelessly suggesting that it was "possibly due to several unidentified and yet unaddressed risky sexual behaviors".
China has previously mounted an effective response to the initial HIV epidemic by providing free antiretroviral to all HIV patients. This does little good, however, if you are afraid to admit you have HIV because it may out you as gay or bisexual. Despite recent improvements in LGBT rights and growing acceptance of LGBT people among the younger generation, being LGBT in China still carries with it significant stigma. This stigma, along with that of having HIV, may be causing young men to avoid seeking help out of fear. To reach out to gay men who may be at risk, the government and concerned nongovernmental organizations are working on novel outreach programs, such as working with dating apps popular with young gay and bisexual men to spread HIV awareness. The director of the Chinese Centre for Disease Control (China CDC), Wu Zunyou, has proposed increasing the availability of HIV self-test kits and pre-exposure prophylaxis medications, both of which would help those at risk whilst lessening the pressure from social stigma. (Kathleen McLaughlin, Science)
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Science Policy Around the Web – June 17, 2016
By: Eric Cheng, Ph.D.
Biomedical Research Funding
NIH gets $2 billion boost in Senate spending bill
The Senate approved a $2 billion dollar boost to the National Institutes of Health (NIH) budget for the 2017 fiscal year. This will increase the agency's overall budget to $34 billion which represents a 6.2% increase from the previous year. This boost in funding represents an increase to NIH's funding for the second year in a row after more than a decade of stagnate funding. NIH received an additional $2 billion last year.
The increase to NIH's funding is the result of bipartisan negotiations between Senate Labor, Health and Human Services, and Education Appropriations Subcommittee Chairman Roy Blunt (R.-Mo.) and Ranking Member Senator Patty Murray (D-Wash.)
"Last year, for the first time in 12 years, we were able to have an increase in [funding to support] NIH research," Blunt said at a subcommittee meeting to unveil the budget proposal. "We have worked hard to repeat that this year." Adding that he hopes to establish a pattern of increases for health research funding, he further noted that "if you are going to have an annual pattern, year two is critical. So we're proposing for the second year in a row we make a substantial commitment to NIH research."
The bill will include $1.39 billion for Alzheimer's disease research, a $100 million increase for Obama's Precision Medicine Initiative, an additional $100 million for the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) brain-mapping project, and $50 million in new spending for a federal initiative to combat antimicrobial resistance. Not mentioned is the $670 million proposal for Vice President Joe Biden's proposed moonshot to double progress against cancer. (Jocelyn Kaiser, ScienceInsider)
Federal Accountability
House sharpens oversight of new NSF facilities
The U.S. House of Representatives approved bill H.R. 5049 by a vote of 412 to nine which would direct the National Science Foundation (NSF) to audit its major multi-user research facilities. This bill was passed in response to the problems that have plagued NSF's National Ecological Observatory Network (NEON) under construction at dozens of sites across the country. Last December NSF fired the contractor, NEON Inc., citing a potential $80 million cost overrun and continued delays in completing the project.
The passage of the NSF Major Research Facility Reform Act of 2016 would direct the NSF to audit its major multi-user research facilities in order to prevent such cost overrun problems in the future. The Congressional Budget Office estimates that conducting these audits required by the legislation would cost about $2 million annually and $10 million over the 2017-2021 period. Specifically, the bill would require NSF to analyze how much every large research project would cost by the first year of the start of construction.
NSF officials remain concerned on how these changes in legislation would affect how audits are conducted and the use of management fees for a contractor. Such additional restrictions on management fees could potentially scare off some highly qualified would-be bidders for future projects. In addition, they believe that the proposed audits would not have caught the problems that NEON faced. (Jeffrey Mervis, ScienceInsider)
Infectious Diseases
Zika virus added to the FDA Priority Review Voucher Program Act
U.S. Senators Amy Klobuchar (D-Minn.) and Al Franken (D-Minn.) supported emergency funding to help stem the spread of the Zika virus in the United States. Over $1 billion in emergency funds passed the Senate today on a bipartisan basis to help mitigate the spread of Zika and respond to outbreaks of the virus.
"The Zika virus is a real threat, and we need action to curtail its spread and encourage the development of treatments and a vaccine," said Franken. "This emergency support will help fight back against the disease, and now, we need to work with the House of Representatives and with President Obama to make sure that the funding measure becomes law. This is far too important of an issue to ignore."
The Centers for Disease Control has reported that over 150 pregnant women in the U.S. have been diagnosed with Zika virus, which can cause a range of birth defects including devastating neurological defects. There are currently no known treatments or vaccines for the disease. The funds will be used to control mosquitos that carry the Zika virus, raise awareness of Zika virus disease, provide education on how to reduce risk of becoming infected, and accelerate development of a vaccine. (Congressional Research Service)
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Science Policy Around the Web – April 1, 2016
By: Ian McWilliams, Ph.D.
Federal Research Funding
House budget plan would rearrange and restrict federal research portfolio
Since the financial crisis of 2008, much attention has been given to the state of the economy. With recent optimism about the health of the economy, the president's new budget plan for 2017, increases the NIH budget in FY 2016, and initiates new research spending for the Cancer moonshot. However, not all agencies are benefiting from the proposed budget. A report filed recently by the U.S. House of Representatives' budget committee could curtail research spending for the National Science Foundation (NSF), the Department of Energy (DOE), and could lead to reshuffling sections of the Department of Commerce (DOC) into other agencies. Current DOE budget speculation is that there will be a decrease in funding for "several high-risk projects" that should be picked up in the private sector. While NSF biology, computing and information science, and math and physical sciences research directorates are to receive "stable funding", the omission of specific plans for engineering, geoscience, and the social and behavioral sciences is ominous. It is unclear how the reorganization of the DOC will contribute to decreases in discretionary spending. The DOC is responsible for the research portfolios of the National Oceanic and Atmospheric Administration (NOAA), the National Institute of Standards and Technology (NIST), and the Census Bureau. (Jeffrey Mervis, ScienceInsider)
Science in the Public Eye
Controversial anti-vaccination documentary pulled from Tribeca Film Festival
In 2010, The Lancet retracted a highly controversial paper by Andrew Wakefield which proposed to link the Measles, Mumps, and Rubella (MMR) vaccine to autism. Since the original publication in 1998, this paper has been a cornerstone for the anti-vaccination movement, even after the paper has been discredited and retracted. Recently, Wakefield himself has directed and co-written a documentary titled "Vaxxed: from cover-up to catastrophe," which claims that the CDC falsified and omitted crucial data linking vaccines to autism. This divisive film was to be screened at the Tribeca film festival , but was pulled, likely due to the backlash over screening the film. The original plan, put forth by Tribeca co-founder Robert De Niro, was to give an "opportunity for a conversation around the issue," but he later decided after consultation that "we do not believe it contributes to or furthers the discussion I had hoped for." In response, Wakefield and Del Bigtree, a producer for the film, released a statement that "We will be pressing forward and sharing our plans in the very near future." With both sides pointing fingers, this argument will likely continue for some time to come. (Jason Ukman, StatNews)
Medical Devices and Testing
Study of Theranos Medical Tests Finds Irregular Results
The first peer-reviewed results of finger prick blood tests offered by Theranos have been published this week and bring more questions about the accuracy of its tests. Theranos, the medical start-up that provides direct-to-consumer blood tests, has come under increased scrutiny after an independent study found irregular results from tests offered by the company. The study, published in the Journal of Clinical Investigation, compared results from 22 different tests offered by Theranos to conventional blood test results from two national diagnostic laboratories, Quest Diagnostics and LabCorp.
Theranos has received much attention for their claims to offer blood tests that require small amounts of blood as a low-cost alternative to conventional laboratory testing. The company offers over two hundred different tests that require only a finger prick compared to vials of blood needed for conventional tests. Elizabeth Holmes, CEO of Theranos, touts the convenience and consumer experience of Theranos's tests. However, the company has been reluctant to release data regarding their tests and has been mired in controversy after a Wall Street Journal article questioned the accuracy of the results of these tests. Furthermore, Theranos' Newark, California laboratory has been cited by The Centers for Medicare and Medicaid Services for problems that "pose immediate jeopardy to patient health and safety."
The current study used 60 healthy, adult volunteers who were tested at separate laboratories on the same day and found more measures outside of their normal range for Theranos's finger prick blood tests when compared to measures from conventional blood tests. Results from Theranos were out of range for 12.2 percent of measurements compared to 7.5 and 8.3 percent for Quest Diagnostics and LabCorp, respectively. Although variability was seen in results from all three labs, Eric Schadt, one of the authors of the study, said that "Theranos was outside of range in ways that would impact clinical decision-making."
Theranos' laboratory directors responded to the study by sending a letter the journal calling the study "flawed and inaccurate." They claim that a large blood draw from a vein could affect the results from a finger prick test and that the study authors did not attempt to determine which measurements were correct. (Andrew Pollack, New York Times)
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Science Policy Around the Web – February 23, 2016
By: David Pagliaccio, Ph.D.
Science in Schools
Climate confusion among U.S. teachers
Despite the vast agreement among scientists that global warming is occurring due to human activities, many difficulties persist in conveying this to middle and high school students. A new survey published in Science indicates that 74.3% of middle and high school science teachers discuss global warming but only at median rate of 1.5 class hours. Importantly, only 54% of teachers are clearly stating that fossil fuel use is a major cause of global warming rather than natural causes. The remainder presents a mixed message about the role that humanity plays in global warming vs. natural factors, denies humanity's role, or does not present the causes of global warming. This may be due to several causes. Luckily, few teachers felt outside pressures from parents, school administrators, etc. to not teach about climate change. Instead, it appeared that a large percentage of teachers did not know the consensus among scientists and thus try to present a two-sided case about global warming. Further, less than half of teachers reported having formal training on climate change during their education though newer teachers were more likely to discuss the human causes of global warming. The authors also indicate a role for sociopolitical ideology where teachers with a more conservative view of the government's role were less likely to emphasize teaching about the causes of climate change. The authors call for improved training, continuing education, and content materials, including updated textbooks, to aid in addressing this issue as well as trying to work to improve science literacy. (Eric Plutzer, Mark McCaffrey, A. Lee Hannah, Joshua Rosenau, Minda Berbeco, and Ann H. Reid, Science Education; USNews.com; NPR)
Science Funding
President Obama has requested increased science funding in his fiscal year 2017 budget, yet people have concerns over the strategy for this and the likelihood of it passing Congress. Particularly, he requested an additional $825 million be allocated to the National Institutes of Health (NIH), but this money was set to come from mandatory funds. Further, $1 million of the NIH's current budget was slated to be moved from regular appropriations processes to mandatory funds. There are concerns that Congress will not approve these mandatory funds, which require that a dedicated funding source be established. If approved, this new money would go to support new cancer initiatives, the Precision Medicine Initiative, and the BRAIN initiative with little going to the other NIH institutes. The Food and Drug Administration (FDA) would also not get much of a general increase in funding but would get money specifically for its role in Precision Medicine Initiative and the new cancer programs – also from mandatory funding. The President has also called for a $500 million increase in funding for the National Science Foundation (NSF) coming from both discretionary and mandatory spending streams. Again, there is doubt that Republicans will approve of allocation through mandatory spending streams that will require selling federal assets, which would leave only a small increase in NSF funding through discretionary spending. While there are many increases in science funding budgeted for, many people are disappointed in the means of funding allocation and are less than optimistic for passing this proposed budget. (Science News Staff, Science Insider)
Federal Regulations
Could FDA E-Cigarette Regulations Help More People Quit Smoking?
While e-cigarettes are generally expected to be safer than traditional cigarettes due to the lack of tar from burning tobacco, research is limited and major health organizations currently do not recommend using e-cigarettes to help people quit smoking. Despite the large and expanding market for e-cigarettes, there are essentially no federal rules or regulations regarding anything about the e-cigarette industry, including sales and advertising. Several attempts have been made to regulate e-cigarettes with the FDA first trying to regulate e-cigarettes as a drug-device combination in 2009. This was overruled by the courts, which deemed e-cigarettes a tobacco product in the next year. Further, the President's Family Smoking Prevention and Tobacco Control Act allowed the FDA to regulate some tobacco products but did not specifically list e-cigarettes. In 2014, the FDA called for authority to specifically regulate e-cigarettes and is awaiting final approval. While no real federal regulations are in place, some states have enacted minimum purchasing age laws, tax e-cigarettes, or call for e-cigarettes to only be used in places where other tobacco products can be used. The science regarding the potential harms of e-cigarettes and any potential benefits to smoking cessation are lacking leading to much fractured debate over regulatory policy, which will continue as the FDA's role continues to unfold. (Michael P. Eriksen, USNews.com)
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About Olds Branch
Olds is a town in central Alberta with approximately 9,184 residents.
Your Olds brokerage team can offer you policies for car and truck insurance, home insurance, business insurance, farm insurance and life insurance. We have access to many other superior products and are dedicated to helping you find the best insurance in Olds, Alberta.
Look no further if you're needing car and truck insurance today. When it comes to home insurance and business insurance, we offer the right protection. Our experts are also your trusted source for farm insurance and life insurance.
At Western's Olds brokerage, we have competitive rates and outstanding customer service. We'll listen to your concerns and help you customize a policy that fits your needs today and as they change.

subset: commoncrawl


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Job Description
My client is situated in an exclusive location in the North shore surrounded by cafes and boutique shops. They have over 100 year's experience in the real estate industry and specialise in commercial, residential and retail property services.
The office is calm and the environment is very supportive and friendly. They encourage agents to grow within the company and they have several events throughout the year within the group to attend.
The Role:
- Administration to the Sales and Admin team
- Answering phone and taking messages
- Handling daily post and booking couriers
- Keeping the office and reception area tidy
- Well Established & Supportive office
- No accounts
- No weekends
- Some flexibility with hours
- Easy parking
- Experience in a reception role essential
- Ability to multitask & prioritise
- Confident telephone manner & administration skills
- Pleasant disposition
- Ability work independently
Apply in strict confidence to:
Yvette Harris 0450 080 085
Or click 'apply" to submit your CV
Thank you for your application, due to the volume of applications we receive, we will only be contacting shortlisted candidates. Please do not hesitate to apply for other jobs.
Please note, not all of our jobs are advertised due to high demand and fast turnover.
Please like our Facebook page to stay up to date on current roles & industry updates.


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Happy Birthday Mary, wherever you are.
Tomorrow, May 15th, is Mary's birthday. I really hoped this year her sister Jenny would be able to wish her a happy birthday in person.
Maybe next year she will.
Take a quick peek at Jen's page? Jen is hands down the hardest searching real kid in all of adoptionville. Let's all hold an image for her that next year, she and her sister will celebrate her birthday together.
ISO my older female sibling 5/15/68 Do you know my sister? Her birthday is getting near!!!!! Maybe she is a friend of yours? A neighbor? Someone you went to school with? She may not even know she is adopted!! Could it be you??
She was born 5/15/68 in Bronx, NY at Misericordia Hospital. Her name at birth was Mary McGrail. She was then surrendered at birth to Nassau County for adoption. She will be turning 39 this year! Her mother, my mother too, was 23 at the time of birth. She was 5'5, 130 lbs Blonde and Blue eyes. She worked for the airlines. She entered the Catholic unwed mothers home 4/17/68 to receive prenatal care and shelter. (To be hidden from the world) She never wanted to give this child up. Times were so different back then and she would have never been allowed to keep her. She never forgot about her first daughter she had to give up. She loved her and mourned her loss her entire life.
Please help me find my sister. I bet she has blue eyes!!! Please help me get the word out that I am searching for her. Please add me as a friend to help me with my search. Please Show this to everyone you know!!! I would be so happy to know that she is well. If you know anything please contact me. If you would like to help me in my search... just getting the word out there for me would be awesome. If you could post this on your bulletin on MySpace that way many more people would see it :) I have posted all over the net.... I am a registered sibling with the state of NY. I have left letters with Nassau County for her. I have joined every adoption registry group i can find. I am also registered with ISRR. I hope and pray I can find her.
Thank you,


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Nidhi Patel
Bachelor of Science in Human Development, UC Davis
Master of Arts in Teaching, Santa Clara University
Multiple Subject Teaching Credential, Santa Clara University
About Me:
I teach 5th Grade at Capri Elementary School. I teach because I want to help children build life long goals that will help them to excel. I'd like to be one of the positive influences in a child's life, where they realize that they can do anything they'd like to if they put their heart into it.
In my free time, I enjoy reading, sewing, knitting, and spending time with my loved ones. I also love hiking and traveling. I play the violin, and I love making up recipes because as a vegetarian, I have found my creativity.
Email is the best way to stay in contact with me, but you will find announcements and messages through Classroom Dojo. Homework is also posted on Google Classroom.


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DYNAJET cycling team taking part in the 24h Mountain Bike Race in Munich, Germany
Aichtal/Munich, Germany. Next Saturday, the starting pistol for the 24h Mountain Bike Race will be fired for the tenth time at Olympiapark in Munich, Germany. At 12 noon on the dot, over 2,000 mountain bikers in more than 500 teams from all over Europe will be leaving the starting line and completing a circuit of 11 km and 100 m in altitude for 24 hours.
DYNAJET will also be taking up this sporting challenge – with a four-man cycling team. Carsten Funk (number 4151), Florian Kiziak (number 4152), Michael Nicklas (number 4153) and Nils Ludwig (number 4154) are entering the race for DYNAJET. We wish them lots of luck and would like to invite customers and partners to support our team in Olympiapark on 9 and 10 June. On the first day of the race (9 June), there will be a firework display over the Olympiapark lake at 10.55 pm to celebrate the 10-year anniversary of the 24h Mountain Bike Race. Admission is free of charge.
Further links:


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Review from Utah Theater Bloggers Association
The reviews are in for One Flew Over the Cuckoo's Nest. The review was done on opening night and we appreciate the efforts of the Utah Theater Bloggers Association. To read the review, check out Utah Theatre Bloggers Website and click on the main picture.


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Burnhamthorpe Primitive Methodist Cemetery
(South west corner of Burnhamthorpe Rd and Dixie Rd)
The cemetery is located in the old village of Burnhamthorpe (formally Sand Hill), now the City of Mississauga, which was named by John Adelson an immigrant from Burnhamthorpe England.
The land on which the cemetery is located was originally a crown grant to Abram Markle who sold the land to Levi Lewis in 1811. In 1825 Lewis deeded nine-tenths of an acre to the trustees of the Methodist Episcopal Church for a public cemetery and school house. The cemetery remained public until 1859 when it was deeded to the adjoining Primitive Methodist Church.
In 1981 the cemetery was still in use and the Burnhamthorpe Public Library was built directly behind it. The cemetery is well kept to this day.
The cemetery has been transcribed three times since 1938, but a burial register had never been found.


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ABM, a leading provider of integrated facility solutions, is looking for a Maintenance Technician.
The Maintenance Technician is responsible to completes assigned preventive maintenance and reactive maintenance repairs requiring conveyor, mechanical, plumbing, electrical, instrumentation, HVAC and other equipment, systems or structures. Performs daily, weekly and monthly rounds and inspections. Responds to spills and other emergency situations, performing tasks necessary for the well being and protection of the environment, property and occupants, in accordance with contractual obligations. Participates in training directed at increasing job-related skills and assists in training of other employees as directed.
ABM is an EOE/AA (M/F/Vet/Disability/Gender Identity/Sexual Orientation)
Category: Cleaning and JanitorJB.0.00.LN
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Magnificent home nestled on the edge of the Trinity Alps Mountains Wilderness Area fronting the designated Wild and Scenic Trinity River in Northern California. Architecturally designed to fully capture stunning river and mountain views, as well as the lush and tranquil surrounding landscape. Enjoy the kayakers, river rafters, and fishermen float by from the privacy of your home. Quality workmanship and materials throughout utilizing this areas finest artisans. Numerous out buildings, guest cottage, small lake, swimming pool with outdoor kitchen overlooking the river, tennis court, garden area, rose garden with rock wall, orchard, bridge, stream, and pathways meander through mature landscaping. Abundance of water, wildlife. A nature lovers paradise in an elegant setting.
Listing courtesy of .


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Revolt- Upcycled Vintage Military Jacket Original Grey
Sorry to late! The product is sold out.
Revolt- Upcycled Vintage Military Jacket in Original Grey with Open Elbow and Light Blue and Gold Silk Trims
- Brand: J DAUPHIN
- Original Military Jacket from the 60 - 70's
- Body: 100% Cotton in Original Grey
- Trim: Open Elbows with Metallic Gold Silk and Light Blue Silk
- Brass Bottons from 19th Century French Navy Made in Paris
- Upcycled locally in Los Angeles
- Sustainable
- No Toxic dyes
- No plastic or synthetic fibers, no plastic packaging
- One of a kind
- Genderless
- Size: M/L
Every jacket is unique, up cycling and repair of holes always create a one of a kind piece not similar to any other piece.


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Official Sponsor
The official sponsor of Texas EMS Blood Month is Texana Public Affairs.
Texana Public Affairs offers services involving public affairs & government relations, advocacy consulting, business cultivation, and more. Texana Public Affairs has over 20 years of legislative expertise at the Texas Legislature and is a Joel Romo group.
Official Partners
Austin EMS Association
The Austin EMS Association represents over 500 EMS Professionals serving the City of Austin and Travis County. They are the largest individual EMS association in the state of Texas.
We Are Blood
We Are Blood has drawn Central Texans together since 1951 to provide and protect the community blood supply. By inspiring people to donate locally and to take pride in this precious shared resource, they're making sure all Central Texans will continue to have access to life-saving blood when they need it.
North Texas Regional EMS
The goal at NTREMS is simple: to make a positive impact on every patient, provider, and healthcare facility they interact with. NTREMS serves the DFW metroplex and is one of the first EMS systems in the nation to carry whole blood products on every ambulance.
Special Adviser
Andrew Fisher, MPAS, PA-C, LP
Chairman | National Stop the Bleed Month
Partnership Opportunities
Texas EMS Blood Month is strengthened by additional partners. Email email@example.com to inquire about an official partnership.


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Christian Yelich says his knee is all healed and he's ready for spring training.
Yelich fractured his right knee cap back in September after he hit a foul ball off his leg. Later that night, the Brewers announced the MVP would be out for the rest of the season. This was just before the Brewer's clinched the wild card spot into the post season.
Christian Yelich left tonight's game with a fractured right knee cap. He will miss the remainder of the season.
— Milwaukee Brewers (@Brewers) September 11, 2019
Initially, there were some concerns that Yelich would not be healed and ready for the beginning of the season, but we have some good news. According to TMZ Sports, our MVP is 100% healed and ready for spring training.
"I'm doing great, man," Yelich says to TMZ Sports. "All good."
Yelich didn't require surgery following the hit, however he was spotted with a cast and crutches following the incident. Now, however, he says he's ready to go.
This is great news for the Brewers and for Milwaukee. Yelich won MVP after the 2018 season and some are suspecting he could even win it again this year. However, that news is yet to be announced.
Even after missing the remainder of the season, Yelich still managed to lead the majors with a .671 slugging percentage and won the "Hank Aaron Award" for the second year in a row.
Who knows what the MVP will bring to the table next season.


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3 June 2016
Seems there's now a 'National Day' for everything isn't there? That said, today is apparently National Donut Day, a worthy contender if ever there was one.
We all love a good donut in the Cow office, especially on a Friday. So when we saw that Nissan had sprinkled 300 donuts using a 370Z sports car, we just had to see it for ourselves.
Check out the video below. Fun.


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The following are 10 lessons that I believe really work for living and maintaining a healthy and fit life. You don't need to spend a lot of money or invest in a fancy program. They are simple and yet they are not always easy. Over the years I have found these lessons to be faithful and true. They are anchors for helping me make healthy decisions.
Lesson 1: Slow down and pay attention. Be mindful. SLOW DOWN! You may be busy with work, family, volunteering, and social activities. And for the most part you have some control over these situations. Choose carefully and stay true to your values.
- Focus on right now – this moment is all you truly have
- Eat your nutritious foods for the day. Slowly and mindfully and if you slip up, clean the slate and start again
- Be grateful and repeat!
"The secret of health for your mind and body is not to wish for the past or worry about the future – but to live in the present wisely and with earnest." (Buddha)
Lesson 2: Live your values.
We all get the same 24 hours a day. What we do, who we spend time with and what we commit to shapes us.
- If you schedule time at the bar after work – it's what you value
- If you schedule time with family each day – it's what you value
- If you schedule time Sunday evening to prep food – it's what you value
- If you schedule time to workout each day – it's what you value
Take time to reflect on your schedule right now. What is occupying your time? Do your daily actions reflect your core principles and values?
Lesson 3: Focus on behaviors, not outcomes.
You can't control what your fat cells will do, nor the exact number on the scale. All you can truly control is your behavior – right now.
- Don't wonder and worry about the future. Focus on one habit at a time. Focus on what you can do right now.
- Consistency equals success. Forget perfect, it will drive you crazy! It is okay to be good enough. Continue to work on improving and getting better.
- Celebrate each victory, no matter how tiny. You are worth it!
Lesson 4: Change what is around you
When you change your environment, change is easier. It removes your means to not change. Willpower and motivation then become optional. Plus willpower tends to be fickle.
- If you want to eat more veggies, keep veggies in the house. Have some ready to go.
- If you don't want to be tempted by the bakery on your way home, find another route home.
- If you want to eat less take out food, get less take out food and get rid of take out menus and numbers so they are harder to find!
Make your environment support your health and fitness journey.
Lesson 5: Live as a fit and healthy person
Think of someone who you know is fit and healthy. How do they live? What is their environment like? What do they do? Now think of someone who is unfit and unhealthy and ask the same questions. What type of person do you want to be? Fit people live a fit lifestyle, hang around others who are fit and support them and surround themselves with things, systems, and structures that make it easier to be fit. And they do things that help them – where they choose to shop and eat for example.
Lesson 6: Be flexible with food
For every strict diet there is a rebound. The more stringent, restrictive "food rules" you come up with, and the more rigidly you try to stick to them, the more likely you will binge. Ironically trying to gain iron fisted control usually results in losing control. Instead be more flexible with food choices and compassionate with yourself. Eat slowly and mindfully. Consider the long term implications of your choices. Acknowledge when there is a family or social gathering. Maybe holiday traditions. Plan and think what they mean to you.
Lesson 7: Think on a continuum.
All food choices are on a continuum from better to worse. Decide if you can and should make a better choice.
- What foods do you consider bad and why? Could you find a way to make them more healthy or good?
- Is a certain food good under the circumstances?
- When deciding alternatives ask… What is the alternative? Is that alternative worse or better? How can I make this choice just a little bit better?
Lesson 8: Focus on adding healthy foods.
A lot of people focus on what they "can't" eat or "shouldn't" eat when they are trying to get healthy and lose weight or maintain. Instead we should focus on what we can and should eat. When we focus on what we are avoiding or resisting, that is all we think about. We miss the wonderful delicious health promoting abundance of food choices that nature provides us. Instead of focusing on eating less "junk" food, focus on eating more of the good stuff. Stuff that satisfies you and earns it's rent. Foods that nourish your body and your soul.
Lesson 9: You won't always feel inspired.
Even fit people don't always want to exercise or eat super foods! They do it anyway, because that is what fit and healthy people do. Sometimes we gotta do stuff we don't want to do. We have to put on our big people pants and just do it! Many of us learned this early in life from our parents or teachers.
- We didn't want to take the trash out or do homework – but we did.
- We didn't want to eat steamed broccoli – but we did.
- We didn't want to stop picking on our brother or sister with the Nerf gun – but we did!
This does not change after elementary school. It continues thru life. Even if we like exercise and eating well, we won't always feel excited about it.
Lesson 10: Find and build social support. Seek support.
Behaviors and attitudes are contagious. Who is in your support network? How do your friends and family shape your mindset?
- Do they criticize your food choices?
- Do they push bigger portions or substitute foods for love?
- Do they choose active or inactive hobbies?
- Do they share your healthy habits?
How can you get the social support you need to be your best and healthiest?
If you are getting started, pick one or two lessons to focus on. And if there is one that hit you as your stumbling block, see how you can improve in that area. Above all, give yourself grace and compassion along the way. Saying and doing hurtful things to yourself is damaging and so unhealthy.
Wishing you a fit and healthy life!
Beth Dean CPT, CES, pn1
PS: This is my last blog. I have enjoyed writing the blogs and have learned a lot about myself along the way – funny how that works! Life is calling me to try other adventures and so I am listening! Thanks my friends for reading these blogs. I wish you Godspeed (you know it is going to be slower, don't you!) 🙂


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Process for manufacturing and use of brines that eliminates the anisakiosis risk
A Spanish research group from the Microbiology and Parasitology Department of Alcalá University has developed a process of manufacture and use of brines that eliminate the anisakiosis risk. These brines contains concentrations equal or superior to 10% of acetic acid, food additive E-260 instead of commercial vinegars, all of them with smaller degrees of acidity able to kill the 100% of the Anisakis sp. larvae. The group is looking for manufacturing agreements.


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Hunt Ridge (GNIS FID: 593666) is a populated place LOCATED WITHIN the Mays Chapel CDP. In turn, the Mays Chapel CDP is located within Baltimore County.
Hunt Ridge is located at latitude 39.435 and longitude -76.637. The elevation of Hunt Ridge is 476 feet above mean sea level.
Since Hunt Ridge is located within the Mays Chapel CDP, all of the census and demographic data for residents of Hunt Ridge are included as part of the information reported for Mays Chapel CDP in the "Profile" tab above.
(Note: CDP = Census Designated Place. A CDP is a statistical area delineated locally specifically for the tabulation of Census Bureau data. While CDPs have specified boundaries, these boundaries have no legal significance.)
Baltimore County: Subdivisions (MCDs) | Cities & Towns | ZIP Codes | Features (airports, churches, hospitals, etc.)
Also See: Nearby Photos | Nearby Hotels | Driving Directions
BIG Map |
Driving Directions |
Terrain Map |
Satellite Map | Data Source - USGS GNIS FID: 593666
BOUNDARY MAPS: Mays Chapel CDP | District 8 | Baltimore County
| Timonium, MD (< 0.1 mile)
Mays Chapel, MD (< 0.1 mile)
Lutherville, MD (1.4 miles SSE)
Hampton, MD (3.1 miles ESE)
Towson, MD (3.1 miles SE)
| Cockeysville, MD (3.4 miles N)
Pikesville, MD (6.1 miles SW)
Parkville, MD (6.6 miles SE)
Carney, MD (6.7 miles ESE)
Garrison, MD (6.8 miles WSW)
| Wellington Valley, MD (< 0.1 mile)
Valleywood, MD (< 0.1 mile)
Seminary Overlook, MD (< 0.1 mile)
Meadowland, MD (< 0.1 mile)
Country Club Park, MD (< 0.1 mile)
| York Ridge, MD (1.4 miles S)
Westwind, MD (1.4 miles W)
Thornleigh, MD (1.4 miles SSW)
Timonium Heights, MD (1.4 miles N)
The Oaks at Five Farms, MD (1.4 miles NW)


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Hello everyone, I have had to take a short break from blogging lately because it has just been crazy busy over the past few weeks, so I am glad to be back! I cannot wait to get back to writing book reviews and post regularly again! A lot of my time at the moment is … Continue reading My Writing Week #7
Month: September 2018
My Writing Week #6
Hello everyone, What a busy week! I can honestly say that I am very happy it's Friday and that I can share my writing progress with you, among some of the other things that are happening in my life! First of all, work has been exceptionally busy. I am a university administrator and term is … Continue reading My Writing Week #6
Poem – To Be Read
Hello everyone, I have written another poem that I would like to share with you. It is about having such a long TBR list and confronting the fact that I will probably never reach the end of it. I am sure many of you feel the same! It may seem fairly short, but it took … Continue reading Poem – To Be Read
Book Blogger Memory Challenge
Hello everyone, I have seen this challenge on other blogs and it looked a lot of fun, so I really wanted to give it a go. A lot of people I know say that I have a good memory, so that also made this an interesting challenge! The Rules: You must answer these questions without … Continue reading Book Blogger Memory Challenge
YA Book Review – The One Memory of Flora Banks by Emily Barr
Pages: 303 Published: 12th January 2017 Started reading: August 26 Finished reading: August 28 Synopsis Flora has anterograde amnesia. She can't remember anything day-to-day: the joke her friend made, the instructions her parents gave her, how old she is. Then she kisses a boy named Drake, and the next day she remembers it. It's the first time she's remembered … Continue reading YA Book Review – The One Memory of Flora Banks by Emily Barr
Monthly Wrap-Up – August 2018
Hello everyone, We have already reached the end of August! It really does seem like no time at all since I was writing my previous monthly wrap-up, but luckily I have managed to get plenty done in the meantime, so I am pleased to say that this was a fairly productive month! First of all, … Continue reading Monthly Wrap-Up – August 2018


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Summit Feature: No feature note: there is an old red brick construction immediately adjacent to the summit
Classification: P30 Tump.
OS Grid Ref: NZ034670 (10 figure Grid Ref: NZ0341967038).
UK Area: 33 - The Scottish Border to the River Tyne (OS Maps 1:50k 87. 1:25k 316W.)
Latitude: 54.997913, Longitude: -1.9481, Height: 189 metres (620 feet)
Prominence: 32 metres (105 feet)
Unique Waypoint POI Name: 0189.- (DoBIH Hill ID: 16051)
Associated Parent Hill:
Tosson Hill (441m, p248)
External Links for Shildon Hill:
-GeoHack link... -OS Map Bing link... -Google Map link... -Geograph link... -Shildon Hill on hill-bagging.co.uk...
Data courtesy of the Database of British and Irish Hills
Selected mapping: Google or Bing / Ordnance Survey:All | :Nearby Hill | :Nearby Trigpoint | : mouseover
Climbed Shildon Hill? Log in to tick it off...
Whittington Hill (1.7km)Carr Hill (2.9km)Harlow Hill (4.5km)Horsley Hill (5.8km)Whittington Fell (6.4km)Duns Moor (7.1km)Snokoe Hill (7.1km)Mickley Moor (7.7km)Moot Law (9.2km)Heddon Common (9.4km)
Andrew Brown Carole cjo Colin Crawford nordicstar rhw scotty299 shorty8282 stevent0809
Total = 1 All
Data courtesy of the Database of British and Irish Hills


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If any of the wines in this week's Featured Wines column tickle your fancy, you can order them directly from Jordan by email (firstname.lastname@example.com) or find him in the Vintage Room of Everything Wine's Morgan Crossing location in South Surrey.
The Hills Have Wines: Gigondas and White Hermitage
Hills are awesome. Not only do they break the monotony of flat landscapes (or "violently disturb the peace" if you're from Saskatchewan), but they provide activities for many, like slinkys, self-aggrandizing snowballs, or little engines that could. Hills rock.
Wine geeks like hills too, but not for rolling down. Hills, depending on their aspect and slope, can provide the perfect conditions for vineyards, staging the vines to better capture the sun, and forcing the roots deeper into the earth by denying them the lazy, yummy topsoil that they would find further down on the valley floor. Hills make great wine, so in a country as wine-soaked as France, they're celebrities (though admittedly so is David Hasselhoff, so that may be a low bar).
Gigondas, a 30 minute drive east of Chateauneuf-du-Pape (11 minutes if French) in the southern Rhone valley, is a hillside village with almost no flat parts, positioned partways up towards the Dentelles de Montmirail (the peaks of this range look like a vampire's underbite). Beneath the village, rocky and sandy soils give fruit and body, while the vineyards around and above the town show typical limestone-y structure and minerality. Overwhelmingly Grenache, the wines are like CNDP's less refined, rural cousin: similar in build, but they don't know any jokes without bad words and they're always kinda covered in dirt.
If you believe the legend, Crusader Gaspard de Sterimberg returned wounded to France in 1224 and built a chapel on top of a small hill overlooking the northern Rhone river (and what is now the town of Tain). He built a small chapel to honour Saint Christopher, and lived there as a hermit until he died, pausing in his prayer and repentance only to tend to his vineyards, planted to the way-cool new grape variety he brought back from the Holy Land: Syrah. Disappointingly, that Syrah Origin Story is false, but the chapel is real and the hill is now called Hermitage, one of the most Rockstar hills in all of winedom. Syrah is fittingly the only red grape planted here, but about 10% of this hill is planted to whites Marsanne and Rousanne, which brings me to:
E. Guigal 2011 Hermitage Blanc
Believe the hype. One hand slaps your face and one hand caresses it, with equal measures of creamy body and citrus/quince bracing acidity. Thick and layered with nuttiness and stone fruits, this is a white wine made for Red Wine Season, predominantly Marsanne (95%), and drinks well now but will develop into something profound. A future classic? 95 points Wine Spectator, $73.29 +tax
Ferraton Pere & Fils 2011 Ermitage Blanc "Le Reverdy"
A joint venture between the Ferraton Family and the Rhone icon Michel Chapoutier (more cool stuff from him coming soon), this equal blend of Marsanne and Rousanne (50/50) seeks to make friends rather than make a statement. Creamy, dry and rich (Rousanne brings the comfort food) showing ginger, peach, pear, honey and vanilla cookies. The spelling "Ermitage" is the traditional one, before French explorers discovered the letter H. 94 points Robert Parker, $116.99 +tax
Chateau de Saint Cosme 2013 Gigondas
The Barruol family have owned and operated this house since 1570, and they're on their 14th generation farming this village-altitude vineyard Le Poste, which surrounds the family's iconic chapel. They manage to attain a certain timeless, quiet power here, with super-concentrated, peppery fruit and a long, mineral finish, all of which is accomplished without the "big" glycerine of New World wines, or even of the wines from further down the hill. The perfumed, floral nose evolves pretty much in front of you, and as exciting as it drinks currently, I'm going to put some away until 2020. 96 points Wine Spectator, $141.99 +tax
E. Guigal 2011 GigondasOk, here's the delinquent in this group. As pretty and elegant as Le Poste is, it probably surrenders its lunch money to this bruiser from down the hill on the wrong side of the tracks. Deeper and more ragged, this Grenache has a core of chocolatey tar surrounded by black fruit and obvious wood. It drinks well now (with protein) but time may smooth the contours. 91 points Wine Spectator, $41.79 +tax


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Why Everyone Is Talking About Speedmymac.com Blog and What You Need to Do
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If I had memories like this, I'm not sure I'd ever sleep at night again! Lindsey Presley is the youngest of three sisters, all who grew up in a home with a very abusive father. The 2 older sisters stories were told in the first 2 books in the series, but thankfully I wasn't lost while reading Lindsey's story, despite missing out on the others.
Lindsey is one tough cookie (although anything she bakes is delicious). The first page starts off with a bang as she's abducted in front of friend and Deputy Jeff Gage outside her restaurant. It never slows down. The first action sequence that follows all the way through the incident in the car had me practically biting my nails.
With her past memories of abuse haunting her, she's built up some pretty solid walls around her heart. She doesn't realize she's also built up a wall around a memory from her childhood. A memory that is going to get her killed. Her family is supportive, but the one she finds herself really depending on is Jeff. For Lindsey, it seems, opening her heart is going to be just as scary.
Great read, really intense and I enjoyed the characters' personal interactions. The romantic angle was nicely balanced with the suspense and the faith element. I'd pick up another Ramona Richards book in a heartbeat.
Lindsey Presley certainly can't imagine why anyone would want her dead-though she knows she wouldn't be alive today if not for the local cop who saved her from two murder attempts. Deputy Jeff Gage has worked difficult cases, but with only Lindsey's fractured memories of a broken past to guide him, this is by far his most challenging.
For Lindsey, fleeing the town she has come to call home is unthinkable. Separately, they are vulnerable, but together, Jeff and Lindsey just may stand a chance of catching a ruthless killer.
If you would like to read the first chapter of Memory of Murder, go HERE.
Watch the book video trailer:
The hardest biographical sketch to write is always your own, whether or not you're a writer by profession. You can't decide what to throw in, what to leave out, and whether or not you should list strengths and flaws, or just strengths.
I like writing and telling stories so much that I once tried to live out a few. After getting a master's in English, I went on to be the seneschale of my local Society for Creative Anachronism. I had a rocky start, but I did get better. (Robin Hood, eat your heart out.)
People often ask members of the SCA, "Are you in a play?" so I thought it would be fun to do that, too. For seven years, I produced and performed in shows staged by Nashville's Circle Players.
Although I'm single now, I married in 1982 and in 1987 had Rachel. She's a cutie. Severely disabled, she's the heroine of many an article for Special Ed Today magazine. Rachel's nurse, Phyllis, is the real life heroine of "An Act of Desperation," which I sold to Chicken Soup for the Caregiver's Soul.
I'm not really a complex person, and my dreams are fairly straightforward: sell books, have enough money to pay the bills and travel a bit, and settle into a cottage. In early 2006, I bought the cottage, which is now more or less swamped by books and DVDs. I write at night (I'm a lifelong night owl), and I occasionally escape by scuba diving, hiking, dancing, and going to movies and bookstores.
I've gone to the same church since 1993, and I even sing in the choir. It's a small but awesome church. I'm no angel, although occasionally I play one in the backyard.
I like staying busy. Life is too short not to follow your dreams.


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A woman who has had secondary cancer for five years is calling for people to 'Wear it Pink'.
Mary Huckle, 54, from Bush Hill Park, Enfield first found out she had breast cancer in August 2007, but after her cancer went into remission, finding out she had cancer again in 2014 turned to be "worse than the first time".
The mother of three was forced to be tough, even though she saw her family and friends struggling with the news of the return of the cancer.
Speaking about the discovery of her secondary breast cancer, she said: "You know you'll never be free from treatment.
"It's devastating and really hurts me to see them (friends and family) hurt as well, with each set back people 'is this going to be it' and if the treatment will actually work."
In a Facebook post she shared to her social media network, she bravely wrote "people see me, and they don't see breast cancer", which she still stands by.
Ms Huckle said: "On the outside, I appear relatively healthy. People don't see anything wrong. It's like having an invisible illness."
Now Ms Huckle is no longer undergoing traditional chemotherapy and instead takes oral chemotherapy tablets to treat her ongoing condition. While she still has cancer, she says she is reacting to the treatment really well and can continue living life as fully as possible.
She has been working with various charities ever since being diagnosed with cancer and hopes that she can raise more awareness and funding specifically for secondary cancer patients as she feels it is often underrepresented over primary cancer.
Wear It Pink Day, an annual breast cancer awareness campaign on Friday (October 18) will have an event held at Queen Anne's Place, Bush Hill Park between 9am and 5pm to raise money for Breast Cancer Now, a cancer research charity.
Stantons Coffee will be helping out at the event, with St Anne's Choir performing and attendance from the Mayor of Enfield.
Ms Huckle is helping host the event and encourages everyone to wear pin, donate, enter the raffles, enjoy shopping and more at the event. Last year saw nearly £3,000 raised, with hopes to raise more in 2019.


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Malaga, 19 enero 2015
Euronutra has been honored with the visit of Margarita Salas, a prestigeous Spanish biochemist who has been actively involved in the promotion of scientific research.
She went to New York to do her postdoctoral work under the direction of Severo Ochoa at the Department of Biochemistry, University of New York, from 1964 till 1967. Her work there was "Reading direction of the genetic message and mechanisms of initiation protein biosynthesis".
Margarita had a lot of support from the Nobel Prize Severo Ochoa who trusted in her and her capacities, something very rare by that time in a world dominated by men.
She has published a large number of scientific works. She currently runs the lab at the Molecular Biology Centre in the Madrid University. Along her career, she has promoted Spanish research in the biochemist and molecular biology fields.
About her visit to Euronutra facilities we would like to point out that she was very impressed by our research capacity as she was by our technology.
Margarita Salas was visiting the PTA because she was called to inaugurate a street named after her. She was accompained by the chancellor of the university of Málaga Adelaida de la Calle, the Mayor of Málaga Francisco de la Torre, the director of the technopolis Felipe Romera, The president of the Technologic Park of Andalucía José Luís Ruíz Espejo, the delegate of equality, health and social politics and Enrique Viguera professor at the University of Málaga.


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2017: Short vintage of intense wines with huge potential
After an expected short harvest, characterized in addition by the diversity and severity of meteorological inclemencies that affected vine development, Miquel Salarich, Enology Director in Segura Viudas, confirms that 2017 wines are intense in flavors and aromas with a huge potential for ageing well, both sparkling and still wines. April and May -both crucial months for grapevine development- registered short precipitations; in addition, there was an unusual heat wave in June, which accelerated the vegetative cycle of the plant. In this situation, it was crucial to do a proper follow-up of the vine ripening, and to choose the optimum harvest time for each variety, as to preserve the best potential and freshness of the fruit. Winery saw 20% less of grapes than usual, but the fruit came in excellent phytosanitary situation, and showed high potential alcoholic strength. Under these conditions, the final wines would show aromas of full maturity, fruity flavors and moderately high acidity. Splendid conditions for ageing wines.
Historical harvest
Harvest of 2017 started on August 2nd being the first time in the story of the winery that it began that early, and It started by collecting Pinot Noir. Traditional varieties to produce Cava also advanced their harvest and the last Parellada's entered the winery by the end of September, almost fifteen days before to what we were used to.


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Everything posted by Lastczarnian
Mad King Aerys is causing us problems
Lastczarnian replied to Lastczarnian's topic in 2. AGoT Rules DiscussionThanks for the suggestions. I have recently added Milk of the Poppy, Nightmares and Turncloak to deal with him.
Mad King Aerys is causing us problems
Lastczarnian posted a topic in 2. AGoT Rules DiscussionOk I got a few scenarios and I'm not sure how each should be handled with the Mad King in play. 1. If my opponent has the Mad King and no other character in play and I win a Military challenge does the Mad King die to the challenge even if I do not have a Noble character in play? 2. If my opponent has the Mad King and one other character in play and I win a 1 claim military challenge can he pick the Mad King as the claim target leaving the other character to live or since the Mad King cannot die does my opponent have to choose the other character? 3. Same as above but with a 2 claim challenge. Can he even pick the Mad King to satisfy the claim? 4. Will Valar Morghulis kill the Mad King? What about Wildfire Assault? Any good ways to get rid of this guy if you have no nobles in play? LOL
How does Astapor work?
Lastczarnian posted a topic in 2. AGoT Rules DiscussionI think we are using it the wrong way which makes it too powerful. Can you give a Dragon who is attacking +2 then if he wins the challenge unkneel him then attack again with him using a different challenge then if he wins that challenge unkneel him again?
Can a character who do not kneel to attack?
Lastczarnian posted a topic in 2. AGoT Rules DiscussionCan a character that does not kneel to attack make two attacks in one challenge phase? For Example, can a character with two icons(military and power) that is not required to kneel to attack able to make a military then a power challenge in the same phase?
Hey new to the game character question
Lastczarnian replied to BigBillyBaratheon85's topic in 4. AGoT Deck ConstructionSo no matter what set a character comes form you can only have 3 with the same name?
Lyseni Captain
Lastczarnian posted a topic in 2. AGoT Rules DiscussionWhen I play Lyseni Captain and pay two gold can I move power from one of my opponent's characters to the Captain?
New players in Kentucky
Lastczarnian posted a topic in 7. AGoT Metagame DiscussionsIs there any organized play going on in Kentucky?
Thanks for the help. You will probably be hearing from me again when we get more cards and run into more situations. This is a great game that does not get enough credit.
I just started playing last week with my family and we are only using the Core set so far. We are trying to learn how to play from watching youtube videos and reading the forums because we do not have anyone to teach us or even a local shop to play at. We have several questions about specific cards that are not covered in the FAQ or errata lists. 1. When using Robb Stark and you win the military challenge do you choose and kill one of the losing players characters even if that character did not participate in the challenge? Just to be sure, you choose after your opponent chooses who dies from the challenge right? 2. When my opponent has Viserys or Ser Davos in play can they always choose him if I win a military challenge? This seems over powered because he always returns to their hand and is played again next turn. 3. When using a card like Strong Belwas can I choose to save a character that was chosen as the killed character because of a military challenge? 4. If I have a location like Great Hall can I kneel it to make a Baratheon character cost 0? 5. When playing Lion's Will can I pay 4 gold to kneel two characters? 6. If I have Lightbringer attached to a character can I kneel it instead of killing the attached character for a lost military challenge. This seems over powered as well.


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Farmer Profiles
Displaying 1 - 4 of 4.
Georgie Brayfarmers_and_growersThe RSPB bought Hope Farm, a conventional arable farm in Cambridgeshire, in 2000, with the aim of developing and trialling farming techniques which produce food...RSPB Hope Farm, Knapwell, CambridgeshireIntegrated Farming
Mark Leafarmers_and_growersGreen Acres is an organic mixed arable and livestock (beef and sheep) farm that my wife Liz and I have been farming organically for 18...Green Acres Farm, Kemberton, Shifnal, ShropshireOrganic
John Pawseyfarmers_and_growersOur crops are all grown for specific markets. We grow organic wheat, barley and beans for British Quality Pigs's organic herd, which are sold in...Shimpling Park FarmOrganic
Iain Tolhurstfarmers_and_growersTolhurst Organic is located on the Hardwick Estate in south Oxfordshire, between the Chilterns and the river Thames. The farm is made up of 17...Tolhurst Organic Partnership CICOrganic
Learn more from farmers and growers using agro-ecological farming practices to enhance production and sustainability in the field.
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text: Christopher Dorner was an ex-LAPD police officer and former United States Navy reservist who was charged in connection with a series of shooting attacks on police officers and their families from February 3–12, 2013. The attacks left four people dead, including two police officers, and left three police officers wounded. Dorner was the subject of one of the largest manhunts in LAPD history. spanning two U.S. states and Mexico


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For Moms, Moms-to-be, and Toddlers+
As a parent, it is often a struggle to find treats that are not only healthy, but that your kids will actually ...
Our reviews are tailored for you - Moms and Moms-to-be who are concerned with the health and nutrition of your kids and loved ones. From healthy snacks to skin care needs, we cover some of everything!
Plus, we only review products that are full of good-for-you ingredients, so you can be sure that if there is a product listed, it is Healthy.Fit.Fab. Mom approved and something we feel comfortable giving to our own families!*
*Not to say that all of the products we review are something we can't live without, but you can at least be certain that they are safe and not full of harmful ingredients, unless noted.
NOW Review: Affordable Health Products
The Gluten Free Bar Review
Updated R.E.D.D. Bar Review
Modern Health Brands that Bring You Feel Good Foods
Being a mom is tough! Whether you are pregnant with your first or are working on your own version of The Brady Bunch, you most certainly never have a shortage of things to do and people (or a growing belly) to take care of! You are the lifeline for keeping it all together and when things start to go awry, everyone turns to mom to make it all run smoothly.


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Conditional Sentences
The sentence that begins with if known as conditional sentence.
Remember, had, were, in case, unless, provided, provided that, providing that, when can be used instead of If.
Try to understand If Clause and Main Clause
|If Clause
|Main Clause
|1. If I wake up early,
|I go jogging.
|2. If I have enough money,
|I will go to Japan.
|3. If I have enough time,
|I'll watch the football match.
|4. If I had wings,
|I would fly.
|5. If I had time,
|I would drop you off at school.
|6. If he had been careful,
|he wouldn't have had that terrible accident.
|Main Clause
|If Clause
|1. I go jogging
|If I wake up early.
|2. I will go to Japan
|If I have enough money.
|3. I'll watch the football match
|If I have enough time.
|4. I would fly
|If I had wings.
|5. I would drop you off at school
|If I had time.
|6. He wouldn't have had that terrible accident
|If he had been careful.
There are four types of Conditional sentences
|If clause
|Main clause
|1. Zero
|General truths
|Simple present
|Simple present
|2. First
|possible and very likely
|Simple present
|Simple future
Imperative sentence
|3. Second
|possible but very unlikely
|Simple past
|4. Third
|impossible to fulfill
|Past perfect
Four types of Conditional sentences in details
|Zero conditional
|If + Simple present + Simple present
|First conditional
|It is possible and very likely that the condition will be fulfilled.
If + Simple present , sub + shall/will/can/may + verb1 + ext.
If + Simple present, Imperative sentence
|Second conditional
|It is possible but very unlikely, that the condition will be fulfilled.
If + Simple past , sub + would/could/might+ verb1 + ext.
Or, Were I a bird, I would fly at large.
Or, Had I enough money, I would start a business.
|Third conditional
|It is impossible that the condition will be fulfilled.
If +past perfect, sub + would/could/might+have+verb3+ext.
Or, Had I seen her before, I would have disclosed the truth.
|If my husband has a cold, I usually catch it. If public transport is efficient, people stop using their cars. If you mix red and blue, you get purple. If this thing happens, that thing happens. If people eat too much, they get fat. Snakes bite if they are scared. If babies are hungry, they cry If you cross an international date line, the time changes. If it rains, the grass gets wet. Wood doesn't burn if there is no air. If you do not exercise, you gain weight. If I don't study, I don't do well on tests. If you are not on time, you lose one mark. If it rains, tennis lessons are held in the gym. If Rana is out of the office, I take his calls. If you heat ice, it melts. Ice melts if you heat it. When you heat ice, it melts. Ice melts when you heat it. If it rains, the grass gets wet. The grass gets wet if it rains. When it rains, the grass gets wet. The grass gets wet when it rains. If you freeze water, it becomes a solid. Plants die if they don't get enough water. If water reaches 100 degrees, it boils. You get water if you mix hydrogen and oxygen. If you touch a fire, you get burned. People die if they don't eat. If I eat peanuts, I am sick.
The zero conditional is also often used to give instructions, using the imperative in the main clause.
If Ashraf phones, tell him to meet me at the cinema. Ask me if you're not sure what to do. If you want to come, call me before 5:00. Meet me here if we get separated. If he gets there before me, ask him to wait. If you leave the room, turn off the lights. Enter through the left if you have your ticket already.
If I invite you, you (come). If it rains, I (not go) to school. If I want, he (give) me. If they ask, he (disclose). If I (see) him, I will call him. If you run in the rain, you (catch) cold. If you work hard, you (prosper) in life. Memory will not go out if it (rain). If you finish the work in time, you (get) a prize. If they come, I (be) happy. If you write the letter, I (post) it. If it (rain), I will not go to play. If he reads attentively, he (pass). If it rains, I (go) to the park. If I study today, I (go) to the party tonight. If I have enough money, I(buy) some new shoes. She (be) late if the train is delayed. She (miss) the bus if she doesn't leave soon. If I see her, I (tell) her.
If her uncle (arrives), I would meet him. If I (know) her phone number, I would call her. If I got a student visa, I (get) a great chance to study abroad. If I (am) a king, I would help the poor. If you (come) here, I would give you the news. If he studied regularly and seriously, he (do) well in the examination. If I were a king, I (help) the poor. If he requested me, I (go) there. If they tried, they (succeed). If I were a bird, I (fly). If he came, I (go). If I had enough money, I (set) up a hospital. If you tried, you (do) it. If I had extra books, I (lend) him. If I had the wings of a Dove, I (fly) to you.
If he had studied very seriously, he (make) a bright result. If she had not missed the interview, she (get) the job. If I had had your number, I (call) you but I had forgotten it. I (order) a taxi if you had told me. I would not have said that if I (have) there. Had I the wings of a bird, I (fly) like a bird. If I had been a rich man, I (help) the poor. Had I been a rich man, I (help) the poor. We would have come, if he (invite) us.


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What are the biggest mistakes in life that a baby or a teenager can commit? Asia is a very young girl with a brave heart. But being so young, she tends to make the worst mistakes ever. In this scary adventure, Asia has to learn from mistakes. How to forgive the worst mistakes in life?
The Chronicles of Asia
How to Make the Best and Easy Hairstyle for Summer Heat
What is the best and easy hairstyle to overcome the summer heat? For a little girl like Asia, this is a dilemma of every new summer.
Easy hairstyles to do at home are always a good solution. But in summer you may need to don't cover neck and ears. Would you look for simple hairstyles?