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Didn't Koeman give him the captain's armband for a couple of games?
1-3 happened on Koeman's watch. Maybe it was a coincidence and he was just done. However, let's face it from Day 1 pretty much he was Koeman's whipping boy and the one that was dropped and/or chewed out in the media. Koeman tried to get in Sigurdsson in pretty much every transfer window before this one so maybe he knew he was for the chop as soon as his replacement came in and started making plans.Regarding 4, he's not said anything before or after in public so nothing has really changed there. Personally I don't mind that, I'd rather he dealt with the club directly than via Twitter.
If he wants to have a better chance of winning trophies, improve as a player and forge an England career he'll go to Spurs.No brainer.
I think you have hit the nail on the head ,all the squad players get a medal .If he wants to be a special player he should stay with his boyhood club and prove me wrong .
So if he stays he's a special player but if he goes to Spurs he's suddenly not that good anymore and only a squad player. Right, okay.
Reading Unsworth comments about him being 3 to 4 weeks away I would be annoyed if he played him (if still in charge) if he hasnt committed by then. Personally I think hes gone and I dont want us to invest anymore time in him
Yeah - I'd hate it if he helped us win some football matches while he's still here.Would much rather he got paid his obscene Premiership footballer's wages just to fuck about at Finch Farm having massages and jacuzzis and shit.
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Department of Surgery faculty members, both physicians and scientists, are world-renown in their subspecialties. Faculty members are passionate in their clinical care and research practices, as well as being mentors for medical students and trainees. The department also invests significant funds to provide protected time and lab space for junior faculty to perform research.
Yuri S. Genyk
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subset: commoncrawl


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Every day in the Council for British Archaeology is different. Every day throws up new challenges, whilst offering new opportunities.
As Director of the CBA a brief diary of today runs as follows:
- start the day by buying the Yorkshire Post on my way to work as I am featured today as part of the promotion for the 2012 Festival of British Archaeology. Quickly skim the article and experience relief that it comes across positively, though there are some relatively minor errors. The Festival is the CBA's major flagship annual event with nearly 800 separate activities taking place this year across the UK. The PR agency is doing a good job to promote the Festival and there will be more media interviews to come in the next few weeks.
- first meeting of the day with colleagues to discuss the next stage of development with various information services that the CBA runs, including the Training Online Resource Centre. We are hoping to integrate our various information services more closely in the coming years to provide better value-added services for users to enable them to access information about archaeology more easily.
- after a quick trip to the opticians for an eye test, it is back to office to meet with a prospective volunteer who wants to help the CBA and gain confidence and experience to help them back into the workplace. It is good to talk to anyone who is passionate about archaeology and we are able to explore a number of options which may suit. I'll follow that up later in the day with colleagues to see what we can offer. Volunteers play a key role in the work of the CBA and there are a number of ways in which people can engage with our work.
- time to catch up with the morning's emails from a diverse range of internal and external colleagues. Key issues include following up on a meeting the previous day in London to discuss setting up a major new public participation project to identify and record physical remains in the UK which relate to World War 1, and also work on a new digital platform to promote the work of the CBA which we are hoping to launch in time for the Festival in July.
- working lunch with a colleague from English Heritage who is in York for a meeting at the University, with skills and training as the main topics for discussion. The Federation of Archaeological Managers and Employers is hosting a meeting on the topic in York next month and there is going to be a focus on training in the 2013 Heritage Counts in England, with a new round of the Profiling the Profession just starting up to gather data on everyone working in archaeology at the current time. Inevitably these are crucial issues at the present time with the ongoing reduction in public funding for archaeology and the consequent drop in jobs and loss of skills.
- back from lunch and straight into a meeting with a colleague who will be leaving the CBA within a month to plan the best use of her remaining time and the transition to new staffing arrangements. The CBA has had a lot of staffing changes in the last six months, some due to redundancy and many due to colleagues moving on to pastures new. The latest departures provide further opportunities for restructuring to ensure that we have the skills and experience that we need to take our plans forward. Membership is a key issue for the CBA at the present time as by growing the membership we can broaden our public education role, strengthen our advocacy and achieve a more secure financial base. I hope that everyone reading this will consider joining the CBA if they are not already signed up!
- brief chat about how we can celebrate the 40th anniversary of the foundation of the Young Archaeologists' Club (which started as Young Rescue in 1972). It would be nice to do something but staff resources are stretched.
- time to plan for the weekend and yet more proof that archaeologists never stop as I'm off down south on a 'secret mission' linked with my role as Chair of the British Archaeological Awards. Our major awards ceremony is coming up and will include a number of surprises but all will be revealed at the British Museum on 9 July!
- back to the emails (which also never stop!) and my never-ending battle to end the week with a clean in-tray (no chance this week!)
- more planning for the CBA weekend event in mid September to follow upon a visit earlier in the week to some of the sites which we are including. I'm going to try to visit the only site we didn't see on my way down south tomorrow. It should be a fantastic weekend in September as we take two full coach-loads of archaeology enthusiasts to visit Buxton, the prehistoric landscape of Stanton Moor, the amazing industrial archaeology of Masson Mill, the medieval castle at Bolsover and the palaeolithic archaeology of Creswell Crags.
- last task of the day is to catch up with other staff colleagues about the outcome of various discussions that took place during the day. The pace of work these days never seems to allow enough time to talk to everyone. I'm tempted to encourage people to go to the pub to celebrate a successful Day of Archaeology but I need to be home to take my son to scout camp!
- later I resume engagement with the week's emails and finally sum up the day in this blog post.
Another varied day in the CBA promoting 'archaeology for all'.
Mike Heyworth


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MONTREAL — Before last weekend, most Quebecers had never heard of the Montreal, Maine & Atlantic Railway, the company at the centre of the Lac-Mégantic disaster.
In a country with a rich rail history dating back to the 1800s, it's a relative newcomer on the scene, in existence since only 2003.
And it isn't actually Canadian.
The company is based in Hermon, Me., and the enterprise with which it's affiliated, Rail World Inc., is a Chicago-based rail management and investment company.
According to the MMAR website, the company has about two dozen locomotives, 170 employees and 800 kilometres of track, including the ill-fated stretch from Brownville Junction, Me., to Lennoxville, sold by Canadian rail heavyweight Canadian Pacific in the mid-1990s.
In comparison, Canadian National has 35,400 route kilometres of track and 22,000 employees, while CP has 23,600 kilometres of track and 16,100 employees.
MMAR says it has the shortest, most direct traffic link between northern Maine, Saint John, N.B., and Montreal, and also serves customers in Vermont.
But it's been financially challenged from the time it started, largely because the lumber and pulp-and-paper industries that used to sustain it continue to struggle.
In 2010, the company sold 375 kilometres of rail line in Maine that it planned to close for $20.1 million. The state was the purchaser.
The following year, MMAR was put up for sale.
According to a story last summer in the Bangor Daily News, the company's outlook finally was brightening after several years of operating losses, in part because of new business shipping petroleum products to Irving Oil.
Louis-François Garceau, a longtime conductor/locomotive operator for CN who now organizes an annual conference for the rail industry in Quebec, said it's harder for "short-line" railroads like the MMAR to make money, but he'd heard nothing negative about the company.
Montreal, Maine & Atlantic Railway was created after the bankruptcy in 2002 of Iron Road Railways, which had itself taken over the century-old Bangor & Aroostook Railroad when it went bankrupt in 1995, a casualty of declines in Maine's manufacturing and pulp-and-paper sectors. Iron Road also bought the Brownville-Lennoxville line from CP.
Provincial pension-fund manager Caisse de dépôt et placement du Québec was part of the investing group that helped acquire the Iron Road assets. It invested $7 million for a minority stake in MMAR and lent it another $7 million. While the loan was repaid in 2011, it estimates the current value of its 12.7-per-cent holding in the company at "practically nil."
Chairman of the board Edward Burkhardt's company Earlston Associates holds 72.78 per cent of the shares, the Caisse said in a statement.
MMAR began operations in January 2003, but within days of starting up announced a 25-per-cent reduction in employee salaries because of the unexpected bankruptcy of a Maine paper company that represented 25 per cent of all traffic on its system.
"These events will upset everyone's lives," president Robert Grindrod said in a letter to MMAR employees dated Jan. 16 of that year.
"All of us have concerns in the back of our minds. While you are distracted, you will be more subject to a small mistake that could result in an accident or an injury. Keep your mind in the game, and come safely home to your family every day. That is what matters most of all."


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This indicates the location of a UCC congregation that is accessible to persons who have a physical disability.
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The Open and Affirming Coalition also provides information about ONA colleges and campus ministries, health and human service ministries, national ministries, online and virtual congregations, seminaries, conferences, and associations within the United Church of Christ.
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Deutsche Welthungerhilfe and FAO intensify cooperation
Agreement covers food security, right to food, land tenure rights and sustainable development
The non-governmental organization Deutsche Welthungerhilfe and FAO will work more closely in their fight against hunger and poverty. The organizations signed an agreement on Monday in Rome, to promote the progressive realization of the right to food and improvements of the governance of land tenure for the benefit of all, with an emphasis on vulnerable and marginalized people. "Only if we work together will we be able to successfully eradicate hunger and poverty," said FAO Director-General José Graziano da Silva. "Cooperation with civil society groups like Welthungerhilfe is crucial to make the right to adequate and healthy food a reality." Deutsche Welthungerhilfe and FAO will work closely together to:
- engage in joint operational and training activities to promote and enhance food security and responsible governance of the tenure of natural resources;
- organize policy seminars, conferences, training workshops and expert meetings for promoting food security and sustainable economic development at global, regional and country level;
- promote networks on global, regional and national level in the fight against hunger and poverty;
"Deutsche Welthungerhilfe and FAO are both focusing on the eradication of hunger. The new cooperation will aim at results-oriented initiatives like the creation of Agriculture Business Centres to exchange knowledge about innovative agricultural production methods with smallholders and to inform about land tenure rights and how they can be realized," said Wolfgang Jamann, Secretary-General of Welthungerhilfe. Welthungerhilfe, founded in 1962, grew out of FAO's Freedom from Hunger Campaign. It has carried out more than 7,100 projects worth approximately € 2.5 billion in more than 70 countries in Africa, Asia and Latin America and is presently working in 39 countries.


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20 Chengzhong Rd, Jiading District 2001069980028 [email protected]
Oct 16th, 2004
Shanghai General Motor Co.
1500 Sheng Jiang Rd. Pu Dong Jin Qiao Export Processing Zone
Shanghai, P. R. China
Post Code: 201206
Tel: 28902890
E-mail: [email protected]
Dear Sir or Madam:
I am writing to apply for the position, advertised in this net.
I feel I am well qualified for the position .At present; I am in the final year of the 3-year university and am a fresh graduated student you preferred. Second, I have a good command of the courses. It is known that the Sydney Institute of language and Commerce is a joint venture between Shanghai University and Sydney Technology University, as a graduate from that institute, there is no doubt that I am fluent at both oral and written English. Furthermore, I early passed the CET Band 4. Meanwhile, I focus on the development of personal computer and am good at Microsoft Office, particularly at word and excel.
In addition to the normal study, I am also in charge of the Student Union of Shanghai University, from which I gain many treasure experience, learn communication skills and teamwork spirit. In spare time, I practice as a manager assistant in an architect design companys marketing department. Another practice was that as a Trainee working in account department of Jennifer Wedding Company.
I am confident that your company, as a booming promising company in the world, will provide the youth a good opportunity to achieve their goals. Your good reputation and nice benefit for the employee are my pursuit. Your promising future encourages everyone to work hard. I am enthusiasm man and have a teamwork spirit. My physical body, education, communication skill can be against the pressure and meet the challenge as well. I consider myself a most suitable applicant for the job.
The accompanying resume should serve to give you an idea not only of my past achievements but of my potential for making a significant contribution to your company.
I am looking forward to your response and would be happy to attend an interview at any time convenient to you.
Very truly yours,
Individual Materials:
Name: Nikki
Chinese name: Yan Guo
Birthday: 10/11/1983
Gender: Female
Health: Excellent
Language Spoken: Mandarin, English,
School-phone: 021-69981746
Email: [email protected]
School: Shanghai University, 2002---2005
Major: International Trade
English Skills:
Good command of English both oral and written.
Especially excellent at written English
Computer Abilities:
A wide knowledge of computer skills such as programming, SQL, office software Dreamweaver, Photoshop, etc
Particular good at Microsoft Office
Gain the honor of outstanding student leaders
Work Experience:
2002.10: the chief organizer of the knowledge contest for Sydney Institute of language and Commerce
2002.10-2003.5: the chief organizer of English club for Sydney Institute of language and Commerce
2003.7-2003.8: as a trainee in accounting department, of Jennifer Wedding Company
2004.6-2004.8: as a manager assistant in marketing department of a design company
Excellent physical body and smart intelligence against pressure
A good communication skill and a strong desire for achievement
A teamwork sprit
I am writing to apply for the position, advertised in this net.
Which position? And shouldn't that be 'website' not'net'?


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Lafuma Mobilier's range of accessories is not really just an accessory... Quite the opposite! They have been designed to simplify the use of various products, as well as making transporting them easier, protecting them in any eventuality, and also to support you in personalising your items as you wish! Renovate your outdoor space quickly and cheaply with coloured replacement fabrics. Choose ultimate comfort by re-covering your famous Relax chair with a comfortable top pad, and have your tea, coffee or cold drink right at hand with the drink-holder tray. Also try the travel or storage covers to protect your tables and chairs. It's mealtime? Perfect! Match your placemats with the chair fabric and colour! Even better: complete the set with coloured edges, specially designed for Anytime table corners. Pink, orange or green... bring some colour to your menus! It's currently on-trend and you'll be the envy of your guests! Thinking of everything, from the essentials right down to the details... this is part of the experience of a historical symbolic brand in the outdoor market!


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evolve is proudly one of the best free WordPress themes. It's built on a solid framework with focus on details and usability which move this theme to the next level, we are not afraid to say to PREMIUM one. Standard of this theme is not only settings of many theme options but its flexibility which let you build any website of your needs - if it's just a blog, e-shop, magazine or any business page. Prebuilt demo layouts with DRAG & DROP builder will let you create new beautiful websites within few minutes! New way of website building has a name - evolve *** IMPORTANT: Please read the changelog.txt file for any important changes before you always update the theme! ***
This theme is made by romik84


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I'm new to photography and I see the term TTL all over the place. What does it mean? And how do I use it to make my pictures better?
2more info here : en.wikipedia.org/wiki/Through-the-lens_metering – decasteljau Nov 5 '10 at 14:27
For completeness: When electronic protocols between devices are discussed, "TTL level signal" can also mean something completely different (and not photography related. It is a standard for digital 5 volt signalling used for all kinds of purposes). – rackandboneman Oct 15 '19 at 15:54
It means "through the lens" and generally it hooks your flash into the exposure system of the camera since the metering of the scene is through the lens. This allows the camera to exert control over the flash, including power, distance, etc. based on the scene and focal length, if the flash supports that functionality with your camera. Usually true for modern flashes made by the camera manufacturer and some third party options such as Metz.
As John says the term is usually used in reference to flash meeting. TTL meeting may improve your exposure it won't necessarily make your pictures any better! Basically the flash sends out a brief pre-flash and measures the amount of light reflected back off the subject through the lens. This is used to judge the required flash power based on your camera settings, the amount of ambient light, subject distance etc. It's helpful when you're moving around a lot and don't have time to be shooting test shots.
It can also be used with multiple off camera flash setups where you can choose the lighting ratios and have the camera work out the flash power for you. Joe McNally is a strong proponent of this way of working.
But for all it's advantages it's ultimately away of determining the correct flash power - TTL alone won't make your photos any better, learning how to use light, blending flash with ambient and most importantly bouncing flash where possible will go further toward making your photos better.
1Although current TTL systems are preflash based, older ones measured during the actual exposure, with a sensor reading reflected light from the film plane. – mattdm May 28 '11 at 12:12
Who's Joe McNally? – Sachin Kainth Aug 28 '13 at 14:42
While TTL is mostly used in context of flash metering, it could also refer to basic light metering through the lens (especially in context of older cameras, when this was a luxury feature). This is how most current cameras meter their exposure. You use it to let the camera set proper exposure for scene you have currently framed, and fine-tune it by setting exposure compensation.
TTL stands for Through The Lens, and in the case of SLR metering, it indicates how the light is measured--that it's the light coming through the taking lens, rather than, say, an exterior sensor.
In flash metering terminology, a TTL system in the camera/flash combination typically means that the camera will tell the flash to send out a small "pre-flash" burst of a known brightness level, meter that flash, and then automatically adjusts the flash power to where the camera's exposure system thinks the power needs to be for good subject exposure, based upon that TTL meter reading. You can think of it like having automated exposure modes on the camera body: just as meter readings are used to automatically adjust the aperture or shutter speed depending on the shooting mode, TTL automatically adjusts the flash power output.
When speaking of a flash, a TTL flash is one that can understand the signalling protocol used to perform TTL metering, and can probably also do a lot of other "extra" features, such as high-speed sync, 2nd curtain sync, zooming, camera menu control, and possibly even has the capability of being a slave in the brand's optical-based wireless triggering system.
When talking about flash radio triggers, the TTL/manual feature distinction is similar. TTL triggers are triggers that are capable of communicating the hotshoe protocol so that features aside from syncing can be sent from the camera's hotshoe to the remote flash foot.
If you look at the flash foot or the camera hotshoe, the pin/contact that's in the center of the "square" is the sync signal. That's the signal that tells the flash when to fire so that it's in sync with the camera shutters and that the light from the flash will be used for the exposure. That is standard across all iso-compliant hotshoes, and is the only signal that's communicated with "manual" flash triggers. Features like TTL, high-speed sync, menu control, zooming, etc. etc. are all done via the non-sync pin/contact. But the electronic communication protocols for these extra features are brand-specific and proprietary. So, flashes and radio triggers that can communicate this information are more complex and typically much more expensive and possibly less robust. But you can have more features to play with.
See also: What features should one look for when selecting a flash?


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This therapist uses a VERY unusual method to relax her patients…
Dr Dot has pioneered a unique therapy known as bite massage – and she's sunk her teeth into some pretty famous rock 'n' roll backs over the years!
Dr Dot has pioneered a unique therapy known as bite massage – and she's sunk her teeth into some pretty famous rock 'n' roll backs over the years!
If you're feeling a bit tense, Dr Dot has got just the thing for you – she'll bite you and pull your hair!
That's right, celebrity massage therapist Dorothy Stein, aka Dr Dot, 48, from New Jersey, USA, has become famous – and in-demand from stars including Kanye West, Simon Cowell and Rihanna – for her unusual bite massage technique.
In this video, wrestler Elena Pogosyan, visits Dr Dot for the first time as a new way of getting a deep tissue massage. As a wrestler, pain is something Elena is used to, but even she hesitates at the idea of a total stranger biting her!
Dr Dot has no such hesitation, though. 'I've seen it all and smelt it all,' she says as she reveals that she sees no need to wipe down her clients before tucking in.
So, how – and why – does someone decide they will make a living from biting strangers? Dr Dot explains that she started her unique method on her mum at the age of 5, because her hands weren't strong enough to give an effective massage so her mum insisted she bite her.
When she was older, she saw it as a way of 'bartering' for tickets to her beloved music stars' concerts – hence why Oasis, Sting, the late David Bowie, The Stone Roses, Keith Richards, Gwen Stefani and Courtney Love have all found themselves on the end of her bite.
No more feeding for Patty
The only way was up!
Let's get ready to rumble!
She concentrates her biting on the client's back, but sometimes moves down to the buttocks. Surely, then, a client getting aroused is an occupational hazard? 'Some people get aroused, yeah,' says Dr Dot, 'it's a normal bodily function. Women get erect nipples, men get erect willies. But I don't go, "Wow! You just pitched a big tent, let's go!" I just ignore it, or sometimes I'll throw extra towels on it!'
To finish the massage, Dr Dot pulls the client's hair, which she says is a great way of increasing blood flow and circulation, to encourage hair growth. As the doc puts it: 'No pain, no gain.'


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ASU Electronic Theses and Dissertations
This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.
In addition to the electronic theses found in the ASU Digital Repository, ASU Theses and Dissertations can be found in the ASU Library Catalog.
Dissertations and Theses granted by Arizona State University are archived and made available through a joint effort of the ASU Graduate College and the ASU Libraries. For more information or questions about this collection contact or visit the Digital Repository ETD Library Guide or contact the ASU Graduate College at firstname.lastname@example.com.
- Jennings, Peter Land
- Arizona State University
- 1 Corley, Kevin
- 1 Hannah, Sean T
- 1 Waldman, David
- 1 Public
- 1 Management
- 1 Organizational behavior
- 1 agency
- 1 character
- 1 ethics
- 1 extreme contexts
- 1 leadership
- more
- 1 virtues
- Reverse Fountain Cytoplasmic Streaming in Rhizopus Oryzae
- Diné Research Practices and Protocols: An Intersectional Paradigm Incorporating Indigenous Feminism, Critical Indigenous Research Methodologies and Diné Knowledge Systems
- Developing an Augmented Reality Solution for Mapping Underground Infrastructure
- Characterization of 2D Human Ankle Stiffness during Postural Balance and Walking for Robot-aided Ankle Rehabilitation
- Using Molecular, Cellular and Bioengineering Approaches Towards Understanding Muscle Stem Cell Biology
After decades of dormancy, character is re-emerging as an important research topic among organizational leadership researchers in response to the need to better explain the source of certain exemplary and ethical leader performance (Hannah & Avolio, 2011; Leonard, 1997; Thompson & Riggio, 2010; Wright & Goodstein, 2007). However, efforts to operationalize character are criticized for their abstract and idealistic trait-based conceptualizations that fail to capture the reality of leadership and situational dynamics (Conger & Hollenbeck, 2010). The purpose of this study is to develop a more robust theoretical approach to character that is empirically grounded in the real life complexities …
- Contributors
- Jennings, Peter Land, Corley, Kevin, Waldman, David, et al.
- Created Date
- 2013


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Finding that a combination of genetic mutations can cause an aggressive form of acute lymphoblastic leukemia could lead to new cancer-fighting therapies
MEMPHIS, Tenn., April 14 /PRNewswire-USNewswire/ -- Researchers at St. Jude Children's Research Hospital have discovered evidence that a series of genetic mutations work together to initiate most cases of an aggressive and often-fatal form of acute lymphoblastic leukemia (ALL).
These defects, known as "cooperating oncogenic lesions," include the deletion of a gene, IKZF1, whose protein, Ikaros, normally helps guide the development of a blood stem cell into a lymphocyte. The researchers also found that loss of the same gene accompanied the transformation of chronic myelogenous leukemias (CMLs) to a life-threatening acute stage.
"These findings provide new avenues to pursue to gain a better understanding of these disease processes and, ultimately, to develop better therapies," said James R. Downing, M.D., St. Jude scientific director and chair of the Department of Pathology.
The new study, which he and his colleagues reported in the advance online publication of the journal "Nature," adds further support to a key concept in cancer genetics: Malignancies frequently require mutations in multiple genes in order to develop.
Cells contain oncogenes, which exist harmlessly until something triggers them to turn the cells malignant.
"It really takes a series of genetic lesions to lead to cancer," Downing said. "You may get activation of an oncogene, but you may also need activation of a tumor suppressor gene and an alteration in a cell-death pathway."
St. Jude researchers sought to identify genetic differences between CML and a form of acute leukemia known as BCR-ABL1positive ALL.
Both diseases are characterized by the Philadelphia chromosome, which results from the translocation (joining) of parts of two different chromosomes. The result of this translocation is the expression of BCR-ABL1, an oncogene.
"It appears from our study, and other work published previously, that all you need to get CML is that chromosomal translocation and BCR-ABL1 expression," Downing said.
In their new study, the researchers re-examined the genetic makeup of 304 ALL patients who had been studied earlier. The group included 43 pediatric and adult BCR-ABL1 ALL patients and 23 adults with CML. Using a more sensitive technology, the scientists increased the number of genetic mutations found in their original gene survey.
In the first study, the gene most commonly altered was one called PAX5, followed by a gene designated IKZF1. Its protein, Ikaros, is involved in the development and differentiation of B lymphocyte cells, which are part of the immune system.
"The vast majority of pediatric acute lymphoblastic leukemias are of B-cell lineage," Downing said.
Among the ALL patients, the researchers found an average of 8.79 copy number alterations, a form of genetic change linked to the development and progression of cancer. The most common change was deletion of the gene for Ikaros.
The gene was deleted in 36 (83.7 percent) of the BCR-ABL1 ALL patients, including 76.2 percent of the pediatric and 90.9 percent of the adult cases.
"The loss of the Ikaros gene is a nearly obligatory lesion for the development of BCR-ABL1 ALL," Downing said, "and clearly must be a genetic lesion that is cooperating with BCR-ABL1."
Moreover, a gene known as CDKN2A was deleted in 53.5 percent of the BCR-ABL1 ALL patients, 87.5 percent of whom also had lost the gene for Ikaros. The PAX5 deletion occurred in 51 percent of the BCR-ABL1 ALL patients; and 95 percent of these people were missing the Ikaros gene.
Among the CML patients whose disease converted to ALL, two out of three had the deletion of the Ikaros gene; a lower percentage of those who converted to acute myeloblastic leukemia had the same gene deleted. That finding suggested that the deletion of Ikaros is cooperating with BCR-ABL1 to cause ALL.
"That is an important finding that may give insight into how that transformation occurs, or it may give insight into a better way to treat the disease, if one can figure out how the Ikaros deletion is working," Downing said.
Other authors of this paper include Charles Mullighan, Christopher Miller, Ina Radtke, Letha Phillips, James Dalton, Jing Ma, Ching-Hon Pui, Mary Relling, Sheila Shurtleff (St. Jude); Deborah White and Timothy Hughes (The Institute for Medical and Veterinary Science, Adelaide, Australia); and Michelle Le Beau (University of Chicago, Ill.).
This work was supported by ALSAC. Mullighan was supported by grants from the National Health and Medical Research Council, the Royal Australasian College of Physicians and the Haematology Society of Australasia.
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital is internationally recognized for its pioneering work in finding cures and saving children with cancer and other catastrophic diseases. Founded by late entertainer Danny Thomas and based in Memphis, Tenn., St. Jude freely shares its discoveries with scientific and medical communities around the world. No family ever pays for treatments not covered by insurance, and families without insurance are never asked to pay. St. Jude is financially supported by ALSAC, its fundraising organization. For more information, please visit www.stjude.org.
SOURCE St. Jude Children's Research Hospital


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The 'Kind of' Weekly Recap (July 24th-August 13th)
Been busy again, but I have been around doing stuff for the Community. With that said, this was one of the busiest periods for us as far as giveaways goes, as you will see in the Community News tab. Currently, we have two giveaways happening with another one starting tomorrow. You can quickly access them by clicking on contest banners between post and at the top of articles.
We've had a number of reviews for you to check out as well, with a few of them happening in conjunction with a giveaway. Thanks goes out to all those PR people for providing us with content! It is much appreciated! I guess Oly gets some credit, too, but we all know people will only associate with Oly because it gets them closer to me :P. I kid.
With that said, EdEN and Cheeto need to settle down with the posting. Especially EdEN and his tyrannical posts about how a 3DS price drop is throwing the gauntlet against the Vita, and how it's a better system than the Vita, blah blah blah. I don't know how he got a staff position. Heck, he still hasn't changed his name to his first name to continue on with site tradition :P. At least Eddie has been putting him in his place. Too bad EdEN doesn't stay there for even 5 minutes before he starts again.
Anyway, be sure to check out the rest! Quite a few articles to go through in case you missed anything!
[tab:Community News & Game Nights]
It's been a really busy past three weeks. One of the biggest things is definitely the giveaways, which you can read about in the section below. As far as Community news itself goes, Tosh has unveiled the new and improved giveaway/lottery system. It not only makes it easier for us to track entries, but also makes it easier for you to enter the contest as well.
Yesterday, Tosh also gave me more permissions for running the forums, so I took the liberty of beginning the process of improving the forums. For the most part, the forums are now categorized satisfactorily, but we're still in the process of moving old topics to their new locations.
And, as always, we had our BlogCasts. Now available are Episode 11, Episode 12, and Episode 13. Enjoy!
Oh, and I almost forgot, EdEN has joined our team. Congratulations!
Alright, giveaways! First of all, we had a winner for the Tekken blu-ray.
The day before the winner of that was announced, we started a giveaway for PSN imports for Yakiniku Bugyou and Rapid Angel, where, later, everyone who entered had won. In fact, you can ask Oly if there are any extra codes left since the number of entries was less than the number of available codes…
Anyway, Eddie did a short giveaway for a Resistance 3 beta code, here you can see who won here.
We still had a couple other PSN giveaways, including Fast Draw Showdown and LIMBO. Winners can be seen here and here respectively.
Of course, it didn't end there. Currently, we have 2 more giveaways going on, including the PSN title Dead Block and a piece of hardware that makes a wired connection through your house's electrical circuit, the HP200AV.
We're still not done yet, though. In fact, we had to make a couple more "lottery" accounts to allow for more giveaways, with the third account being used for a giveaway you will see go live tomorrow, so stick around! There is a lot of free stuff you can win! Also, Tosh's E3 swag giveaway has ended, but items will be shipped soon!
14 Articles // 11 QuickNews
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Since the last recap, we had to delay the GT5 tournament to July 31st, at which point, only Dean and Pedro showed up. Although it was just us three, we still had a bit of fun! We just didn't run it as intended and basically just turned it into a game night, but that's okay. Here's hoping we can do it again some other time.
[tab:July 24th-30th]
Official Cars 2 Review
Eddie on July 25th, 2011 7 Comments
Lack of Innovation? A Counter Point…
Darrin on July 25th, 2011 16 Comments
Rage Behind the Scenes 4 of 6 "Wastelandâ€
Oly on July 25th, 2011 8 Comments
EVO 2011 Live on PlayStation Home
Cheeto on July 26th, 2011 7 Comments
Fast Draw Showdown – 1st Round Gameplay
Tosh on July 26th, 2011 10 Comments
Sony May Bring the PS Vita's Activity Feature to the PS3
Eddie on July 27th, 2011 4 Comments
Comic-Con Recap: Crazy Games, Crazy Times!
PAUL FIERCE on July 27th, 2011 7 Comments
Nintendo to Sony: It's on like Donkey Kong
EdEN on July 28th, 2011 28 Comments
Bleach: Soul Resurrection is Approaching
Jason on July 28th, 2011 12 Comments
Mad Blocker Alpha Review
EdEN on July 28th, 2011 2 Comments
Rage "The Enemy†– Part 5 of 6 Behind the Scenes ad id Software
Oly on July 29th, 2011 2 Comments
The List
Cheeto on July 29th, 2011 15 Comments
New Anarchy Reigns Trailer Is Here!
EdEN on July 29th, 2011 6 Comments
Magic: The Gathering: Duels of the Planeswalkers 2012 Review
premiersoupir on July 30th, 2011 13 Comments
Tekken Tag Tournament 2 Demo Comes With Tekken Hybrid
Sakinah on July 24th, 2011 5 Comments
Twisted Metal Open Beta Denied
Cheeto on July 25th, 2011 5 Comments
Silent Hill HD Collection Launches Exclusively on the PS3 this September or October
Eddie on July 26th, 2011 7 Comments
Battlefield 3 weapons customization videos
Cheeto on July 26th, 2011 3 Comments
Red Dead Redemption Free "The Myths and Mavericks Bonus Pack†Coming in Sep.
Oly on July 27th, 2011 5 Comments
Global Resistance
Cheeto on July 28th, 2011 3 Comments
Do you like THQ? Want 50% off at the PSN Store?
EdEN on July 28th, 2011 3 Comments
Resistance 3 Beta Detailed
Cheeto on July 29th, 2011 4 Comments
Do you own PS Move? Then this list will make you happy!
EdEN on July 29th, 2011 11 Comments
King of Fighters XIII will be out on October… so here's a veeery awesome pre-order incentive!
EdEN on July 29th, 2011 8 Comments
Sodium 2: Project Velocity | Track 3 Preview
Tosh on July 29th, 2011 No Comments
[tab:July 31st-August 6th]
Sony Going All Out To Support Garage Developers on the Playstation Vita
Eddie on July 31st, 2011 13 Comments
House of the Dead: OVERKILL (Extended Cut) – New Level Revealed
EdEN on August 1st, 2011 2 Comments
LittleBigPlanet Toy Story Levels and Costumes!!
Oly on August 1st, 2011 7 Comments
Sony Buys Sucker Punch Productions
Cheeto on August 2nd, 2011 11 Comments
Batman: Arkham City, Pre-Order Skins
Cheeto on August 2nd, 2011 19 Comments
New Technology From Euclideon That Could Change How Games Look For The Next Generation
EdEN on August 2nd, 2011 17 Comments
Number Of PlayStation Pads Damaged/Broken?
Madagasca on August 3rd, 2011 18 Comments
Borderlands 2 Announced!
Pedro on August 3rd, 2011 18 Comments
One Epic Game Released on the PSN Store!
EdEN on August 3rd, 2011 8 Comments
LIMBO Review
Ace on August 3rd, 2011 10 Comments
Rochard Developer Q&A
EdEN on August 3rd, 2011 5 Comments
Fast Draw Showdown Review
Tosh on August 4th, 2011 5 Comments
Vita to miss the 2011 U.S/Europe Release
Cheeto on August 4th, 2011 14 Comments
The Tester Season 3 Has Been Announced and You Can Be In it!
Oly on August 4th, 2011 6 Comments
Ninjamurai Review (minis)
EdEN on August 4th, 2011 3 Comments
Driver: San Francisco Multiplayer Looks Promising
Jay on August 4th, 2011 6 Comments
Where to Get Your Battlefield 3 Pre-Order Goodies!
Madagasca on August 5th, 2011 11 Comments
PSN Play (or how the Xbox 360 Summer of Arcade has changed into the Fall of Fun on Sony's console)
EdEN on August 5th, 2011 11 Comments
Skyrim Collector's Edition Looks Great!!
Oly on August 5th, 2011 11 Comments
Resistance 3 Resist Trailer
Ace on August 6th, 2011 4 Comments
Will Smartphone/Tablet Owners Purchase the Playstation Vita?
Eddie on August 6th, 2011 7 Comments
New Monster Hunter 3 HD Screens Released
Jason on August 1st, 2011 7 Comments
Super Street Fighter IV Patch Before 2011 Is Over
EdEN on August 1st, 2011 3 Comments
Lollipop Chainsaw to be Relased in the US!
EdEN on August 1st, 2011 7 Comments
Assassin's Creed: Brotherhood on PSN EU
Cheeto on August 2nd, 2011 3 Comments
So, how many studios does Sony own after purchasing Sucker Punch?
EdEN on August 3rd, 2011 7 Comments
Call of Duty: Black Ops Rezurrection Pack Announced
Cheeto on August 4th, 2011 No Comments
Rage "Uprising†Trailer
Oly on August 4th, 2011 2 Comments
Twisted Metal Delayed!
Cheeto on August 5th, 2011 5 Comments
Battlefield 3 Open Beta FAQs
Madagasca on August 5th, 2011 4 Comments
Atlus has reason to celebrate: Catherine sold 200,000 in a week!
EdEN on August 5th, 2011 13 Comments
Arkedo Series Coming to PSN
EdEN on August 5th, 2011 2 Comments
Sony's 3D TV Bundle Swaps Resistance 3 for MotorStorm: Apocalypse
Cheeto on August 5th, 2011 10 Comments
[tab:August 7th-13th]
Battlefield 3 is Heading to GamesCom with Jets!
Ace on August 7th, 2011 9 Comments
Dead Island [Red Edition]
Cheeto on August 7th, 2011 4 Comments
[Review Rewind] Magic: The Gathering: Duels of the Planeswalkers 2009
premiersoupir on August 8th, 2011 5 Comments
Dead Island's Zombie Apocalypse Spreads on Central Plaza in PlayStation Home
Oly on August 8th, 2011 2 Comments
New Deus Ex: Human Revolution Videos
Oly on August 8th, 2011 5 Comments
Catherine Review
Darrin on August 9th, 2011 10 Comments
Call of Duty: Modern Warfare 3 Spec Ops Survival Trailer
Oly on August 9th, 2011 11 Comments
Dead Island has Gone Gold and Here's a New Co-op Trailer to Celebrate
Oly on August 9th, 2011 8 Comments
Sony DADC Torched in London Riots
Ace on August 9th, 2011 11 Comments
Champion Jockey: G1 Jockey & Gallop Racer Trailer is Exciting
Oly on August 9th, 2011 9 Comments
Ico/Shadow of the Colossus Collection Intro Videos
Cheeto on August 10th, 2011 9 Comments
Assassin's Creed Revelation Beta for PS+ Subs. Starts on September 3rd
EdEN on August 10th, 2011 8 Comments
New Risen 2 Trailer
Pedro on August 11th, 2011 5 Comments
Hardware Review: HP200AV Powerline Internet AV Kit
Jay on August 11th, 2011 6 Comments
NIS America Weekend Update (on a Thursday)
EdEN on August 11th, 2011 5 Comments
Sniper Elite V2 Trailer
Oly on August 11th, 2011 3 Comments
Dead Block Review
EdEN on August 11th, 2011 8 Comments
Saint's Row: The Third 8 Minutes of Game Play
Oly on August 11th, 2011 6 Comments
[RAGE] First-Time Buyer Incentive!
Cheeto on August 11th, 2011 6 Comments
Hideo Kojima Gives Us A Sneak Peak Of The Metal Gear Solid HD Collection Trophies
PAUL FIERCE on August 12th, 2011 13 Comments
God of War: Origins Collection on PS3
EdEN on August 12th, 2011 12 Comments
Dead Island 20 minutes of Gameplay!
Jason on August 12th, 2011 6 Comments
Child of Eden Trailer for PS3!
EdEN on August 12th, 2011 5 Comments
DeathSpank 3: The Baconing is Going to be Great!
Oly on August 12th, 2011 7 Comments
PSP Remaster Series and Multiplayer
Jason on August 13th, 2011 5 Comments
Lord of the Rings: War in the North Collectors Edition (Europe and Australia)
Cheeto on August 7th, 2011 8 Comments
Dark Souls Delayed
Cheeto on August 8th, 2011 12 Comments
Dead Island Survival Kit CE Only in Poland
Oly on August 8th, 2011 5 Comments
Ken Levine on Bioshock Infinite, Vita, PS Move.
EdEN on August 9th, 2011 3 Comments
Driver: San Francisco Demo Available Now!
Cheeto on August 9th, 2011 7 Comments
PS3 System Software Update (v3.70)
Cheeto on August 10th, 2011 7 Comments
Gotham City Impostors Closed Beta Sign Up
Cheeto on August 10th, 2011 5 Comments
PSN Scheduled Maintenance
Cheeto on August 11th, 2011 6 Comments
Sixaxis Controller With Your Android Phone? Are You Nuts?
Madagasca on August 11th, 2011 3 Comments
Motorstorm now has move support
Jason on August 12th, 2011 4 Comments
Counter-Strike: Global Offensive Announced
Cheeto on August 12th, 2011 8 Comments
WWE '12 Roster Reveal Tomorrow
Jay on August 12th, 2011 5 Comments
Retro/Grade and PAX Contest
Jason on August 13th, 2011 3 Comments
Splinter Cell HD 1080p Gameplay
Jason on August 13th, 2011 3 Comments
[tab:Poll Results]
Pretty interesting results, really. Almost half of the people who voted said that a deep, engaging story is most important for future titles, where, despite being 10 votes behind, innovative gameplay took second. Sequels and prequels got a few votes, but tried and true formulas and controversial subject matter both struck out with one vote.
[tab:New Poll]
This new poll idea comes from mowmow, who will receive 200 points for the idea. With that said, the poll asks what interests you most in a collector's edition of a game. I believe we've had one of these in the past, but I suppose it can't hurt to run a new one.


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Valid for one Dansko clog coaster set per order – order must include footwear. No promo code necessary. The coaster set will automatically be added to your cart. Offer ends 12/01/20 11:59PM EST. Offer subject to change without notice. While supplies last.
When the kitchen is your domain, ensuring you stay in perfect step every minute of your shift is imperative. With chef shoes and clogs from Dansko, you can do just that, all while keeping your feet comfortable and supported. Our kitchen shoes and clogs serve up the most sought after benefits and features for every member of the culinary world! From the front of the house to the kitchen, restaurant shoes from Dansko are available in the styles that best suit your work and surroundings. Select styles include a slip-resistant outsole and are tested on dry, wet, and oily/wet surfaces, helping you perform your duties safely. Our chef's clogs include cushioned footbeds, excellent arch support, and durable materials that have made Dansko footwear the go-to choice for chefs, sous chefs, cooks, waitstaff, hosts, and restaurant managers for over 25 years. Create your next culinary masterpiece in the most comfortable clogs for chefs!
Filter by:Clear All


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'SNL' to air prime-time election spoofs this fall
BEVERLY HILLS, Calif. (AP) -- NBC will air a pair of "Saturday Night Live" prime-time specials spoofing the fall election, and it's leaving the door open for cult-favorite comedy "Community" to continue beyond next season's abbreviated run.
The live "SNL" specials, which follow an election-cycle tradition for the satire series, will air Sept. 20 and 27, NBC Entertainment Chairman Robert Greenblatt announced Tuesday.
He also said that "Community," which hovered near cancellation before winning a reprieve for 13 weeks, could live even longer if it proves itself in its new Friday slot.
"I would love nothing more" than for "Community" to continue, Greenblatt told reporters at the Television Critics Association conference.
Greenblatt made it clear NBC's short-term goals are modest as he referred to his network as "in transition" and "in a turnaround."
"We've very happy that we're No. 3 in adults 18-to-49," he said. "NBC hasn't finished better than No. 4 since the 2003-04 season."
While voicing hope for the quirky "Community," NBC is broadening its approach to sitcoms in an effort to expand beyond the boutique approach that wins acclaim and awards, but not time periods.
One of NBC's new sitcoms, "Animal Practice," centers on a veterinarian who likes animals better than people and whose best friend is a monkey.
Another, "Go On," stars Matthew Perry as a sportscaster who joins a support group after the death of his wife.
NBC Entertainment President Jennifer Salke said "Go On" will "make you laugh, make you cry," with "tons of heart."
Meanwhile, she said, creative teams at veteran NBC comedies "are trying to embrace the idea of staying true to what their shows are ... but opening up things a little bit and trying to be a little more inclusive." She shared no examples.
"I don't want to say anything negative about what ('30 Rock' creator) Tina Fey does, or 'Parks and Rec,' or 'The Office' -- they're great shows," said Greenblatt. But currently they tend to be "a little bit more narrow and more sophisticated than we might want for a real broad audience."
"We are in this sort of awkward stage of taking what's working at the network, and expand it out and build on that," said Salke.
Asked about the much-talked-out hiring of Howard Stern as a judge on "America's Got Talent" -- with a cross-country transfer of the show to accommodate the New York-based shock jock -- Greenblatt said he was "thrilled" with Stern.
Looking beyond this season, he added, "We'd be delighted if Howard wants to come back."


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Lionsgate's Summit Entertainment announced today that the home entertainment release of The Twilight Saga: Breaking Dawn – Part 1 has sold over 5 million DVD and Blu-ray units in the first 11 days of release. DVD sales for the film, which became available at retail on February 11th, are approximately 13% ahead of sales of the third film in the franchise, The Twilight Saga: Eclipse, at the same point in its release. Digital sales of The Twilight Saga: Breaking Dawn – Part 1 are also strong with over 74,000 electronic sell through transactions (53% ahead of "Eclipse" at the same time) and over 175,000 video on demand transactions (162% ahead of "Eclipse" at the same time).
Steve Nickerson, Summit's President of Home Entertainment, stated, "The sales to date of 'The Twilight Saga: Breaking Dawn – Part 1′ are a testament to The Twilight Saga fans' commitment to and passion for the stories created by Stephenie Meyer. We are pleased that we could bring this film to the fans at this time of year, especially given the storyline, with the romance of the wedding and honeymoon."
The Twilight Saga: Breaking Dawn – Part 1 has grossed over $700 million worldwide at the box office to date since its theatrical release on November 18, 2011. The next chapter in The Twilight Saga: Breaking Dawn – Part 2 will arrive in theatres on November 16, 2012. Academy Award winner Bill Condon directed both the first and second part of the two-part finale starring Kristen Stewart, Robert Pattinson and Taylor Lautner. The project, based on the fourth novel in author Stephenie Meyer's "Twilight" series, was written by Melissa Rosenberg with Wyck Godfrey, Karen Rosenfelt and Stephenie Meyer producing.


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Ever since his religious affiliation was outed to the general public back in 2009, Republican Dan Halloran has tried to keep the subject off his adherence to Theodish Heathenism, and on day-to-day political matters. After his Heathen faith became an issue in the successful 2009 campaign for a seat on the New York City Council, he finally released a public statement entitled "I believe in God," which downplayed his Pagan identity, and stressed Halloran's Catholic heritage.
"I took comfort in my family's history and our heritage, yet through all of this pain and hardship, I never lost faith in God. Last week, I was attacked for my faith in the Queens Tribune.These attacks happened on the eve of Rosh Hashanah and Yom Kippur, the holiest time of the year for the Jewish people. Having been raised in a Catholic household that shares its religious roots with the Jewish faith, I was deeply offended that religion would be used for political gain. […] I am a man of faith – and now my faith is under attack by a newspaper working for my opponent. I call on my opponent to disavow the Queens Tribune's attack on religion. I am running a campaign on the issues."
Not once in the statement does Halloran mention the terms "Heathen," "Theodish," or "Pagan." A fact that soured many in the Heathen community to Halloran, believing that they were "thrown under the bus" so he could win the election. From that point, Halloran has steered clear of talking explicitly about his faith, even when journalists dug up former co-religionists who made allegations relating to his leadership role within Theodism. In a 2010 interview with the Pagan Newswire Collective, Halloran reiterated that his faith is private, and "irrelevant" to any policy decision he might make.
"My service in the Council and advocacy for our neighborhoods has proven beyond a shadow of doubt that my religious faith is not only irrelevant to my public policy… but also a source of great personal strength for me which only inures to the benefit of my Community. I do occasionally hear that being a "Druid" explains why I am such an eco-conscious Republican."
However, it now seems like Halloran may be willingly (if unwittingly) opening the "black box" of his religion by attacking one of his potential Democratic opponents in the upcoming congressional race. In an interview with the Jewish political blog Gestetner Updates, Halloran praises Assemblyman Rory Lancman as his toughest potential opponent, but also claims his voting record doesn't reflect his personal faith.
"Unfortunately his voting record does not match his personal commitment to his faith," he said. "He was on the opposite side of gay marriage; opposite side of abortion; and the opposite side on the issues of school vouchers, and tax credits and incentives for those who use private schools to educate our young children."
In short, Halloran kinda implied that Lancman may be a bad Jew when it comes to these issues, echoing the criticisms of conservative New York Jews. That may seem like good politics when you're trying to win over moderate and conservative Jews, but it also opens the "black box" of his own religion, making him fair game for similar questions and statements. Considering the fact that the Village Voice has already attacked Halloran for being a hypocrite, specifically on the question of abortion, it doesn't seem wise to run on abortion and same-sex marriage.
"In early 2011, a legislative fight emerged in New York City over anti-abortion "pregnancy centers" advertising abortion counseling when they don't actually offer abortions. City Council Speaker Christine Quinn introduced a bill that would force such organizations to advertise that they don't perform abortions and to disclose if they have any medical staff on hand. […] Quinn's bill would eventually pass overwhelmingly in the council without Halloran's vote. According to Little Neck Patch, Halloran "did not see the issue . . . as a part of the decades-old debate over abortion rights." (Still, through a spokesman, he also noted "the Council member is pro-life.") […] The episode infuriated some of Halloran's former followers, who not only had known him to be pro-choice, but also to be "pro-abortion to nearly the point of endorsing infanticide," as one put it."
The Voice piece quotes Halloran at length defending abortion within the context of his faith, and while I publicly criticized the piece for crossing the line, this new interview now partially undercuts my argument that "too much is made of his faith, and in improper contexts."
I can only think of three possibilities for why Halloran has decided to bring up same-sex marriage and abortion in the context of a potential opponent's religion: that it was a mistake, that he felt it was a calculated risk worth the potential blowback, or he's hoping to preemptively make the religion question moot by muddying the waters now, instead of during the general election. Whatever the reason, it just seems risky to open yourself up for attack after you've spent years saying your religion isn't an issue for public debate or commentary.
In the coming weeks I'll be highlighting a two-part guest commentary from our resident Theodism expert Nick Ritter on what Theodism is and isn't, and the political career and congressional candidacy of Dan Halloran from a Theodish perspective. I feel that as this campaign heats up, it will be important to talk to voices who can bring more light to the issues that will no doubt be raised regarding religion. In the meantime you can listen to my podcast featuring Nick Ritter and PNC-Minnesota reporter Cara Schulz on Halloran's congressional run. I fear we're going to be hearing a lot about Halloran's faith in the mainstream media come November, and we should be prepared for what that might mean for the broader Pagan and Heathen communities.


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Travel Agent Information
Preferred Travel Agencies
Travel Agents are a vital part of any airport's success. They play a key role in offering you all of the airport, airline and vacation package choices that are available to you.
Below you will find some of the travel agents in our area who do an outstanding job promoting Bishop International Airport and our airlines! They are agencies who always remember to offer flying out of Flint as an option to travelers. We would like to thank all of the Travel Agencies and Corporate Business agencies in the area. Their support is appreciated beyond words.
Below, you will find a list of agencies who continuously support our local airport.
Travel Agency Owners: If your agency is not currently a member of "Check FNT First", and you would like to join, please email us at . Thank you!


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Criminal Procedure and the Administration of Criminal Justice
examines the flow of criminal matters through the criminal justice system. Topics include the investigation into criminal complaints, search and seizure, arrest, release (bail), elections and pleas, preliminary inquiries, trials, sentencing, appeals and the ultimate disposition.
Corrections in the Criminal Justice System
examines the role of corrections in the Canadian criminal justice system which seems to be in constant change. These changes will be reviewed, updated and evaluated as we look at the two-dimensional role of corrections in justice: correctional institutions (prisons) and the community/after-care functions. Includes a review of new Canadian legislation affecting the above areas, as well as an examination of sentencing options and the Canadian pardon system.
Selected Topics in Criminology
will be determined by the Division of Lifelong Learning.


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We believe that an important part of Social Studies is teaching children real life skills, such as map reading and critical thinking skills, for example.
Today's post emphasizes the need for setting and achieving realistic goals. This can be difficult for many people who often are too vague or too broad, leaving them overwhelmed and failing.
We designed this lesson many years ago for our 9th graders and have had much success over the years with all grade levels.
Our Five Goals assignment is ready for your classroom use today, let us know what you think!


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These sixth generation Sprawl fight shorts feature lightweight, four-way stretch fabric that doubles as a sweat and blood repellent, and is fungus resistant. The flex panel inseam allows a wide range of movement and the adjustable channel-lock, no-sli
The Sprawl Fusion Short combines functionality and technology through new unique features. The Fusion Short is constructed with advanced stretch fabric for maximum comfort, an adjustable channel lock waistband with a velcro closure and interior drawst
Streamline your look in this sleek black rash guard with vertical white side panels and contrasting red stitching. Imported.
Sizes: S, M, L, XL, XXL
Color: Black/White
Black and white camo graphics on the left leg and UFC logo over the black right leg creates an eye-catching look. The waistband features a rubber UFC logo on the front tab and at the center of the back. A hook and loop closure and internal drawstring
Learn the unique techniques of takedowns, fighting from top, side and bottom positions along with various combinations to make a more deadly fighter. Six titles to choose from. Fitness Routine Speed, power, strength, stamina, agil
Takedowns And Immobilizations #ALAND-001 The Guard: Sweeps And Passing The Guard #ALAND-002 Chokes And Armbars #ALAND-003 Vale Tudo Takedowns And Immobilizations #ALAND-004 The Guard For Val
hen goes through a variety of techniques including blocking and striking, assorted leg and arm locks, plus self defense and ground fighting. Eleven volume titles to choose from. Volume 1: Total Body Workout Routine Teaches the comp
Eight volume titles to choose from. Blue Belt Techniques Volume 1 Approx. 40 min. #GBLUD-001 Blue Belt Techniques Volume 2 Approx. 40 min. #GBLUD-002 Purple Belt Techniques Volume 3 Approx. 40 min. #GPUR
Four volumes to choose from. Volume 1 Approx. 38 min. #GRAD-001 Volume 2 Approx. 39 min. #GRAD-002 Volume 3 Approx. 51 min. #GRAD-003 Volume 4 Approx. 51 min. #GRAD-004
Learn advanced Judo throws and sweeps, that can be used in street self defense situations. Seventeen volume titles to choose from. Volume 1: Fundamentals and Introduction Approx. 70 min. #JUDOD-001 Volume 2: Yellow Belt Re
The first mixed martial arts inspired gi pants. Channel lock inner waistband system provides stability in the most demanding training and competition situations. Adjustable drawstring waistband with fly vlecro closure. Flex panel in crotch increases r
Action sport leader, Jaco, offers 4 way stretch, breathability, moisture wicking, and a comfortable compression waist system for a no-slip fit with their Resurgence Short. An internal stretch pocket at the bottom leg seam holds a mouthguard. Fly backi
She is an instructor at the Machado Academy located in Torrance, California. Four volume titles to choose from. Volume 1: Basic Cindy starts by teaching some basic warmup drills, shrimping, triangle hip raises, bridges, shoulder r
This exciting historic set features spectacular 1930's pre war footage of Morihei Ueshiba, the founder of Aikido. This extraordinary DVD shows shots of Sensei teaching, performing in demonstrations and much more. See why he is truly the King of Aikid
Jason was one of the first fighters to challenge Royce Gracie, a match that led to his invitation to fight professionally in Japan.
Basic Aikido I - running time 86 min #BLOKD-V01 Basic Aikido II - running time 50 min #BLOKD-V02 Intermediate Aikido I - running time 70 min #BLOKD-V03 Intermediate Aikido II - running time 60 min #BLOKD-V04<
Three volume titles to choose from. Volume 1: Grappling Positions Introducing the essential positions of Brazilian Jiu Jitsu. Discover how to maintain stability of the mount positions and the guard. Approx. 45 min. #189255D
In Mastering Jujitsu Gracie, one of the most successful athletes in the world renowned Gracie family, reveals the inner workings of the Brazilian brand of art. The book covers everything from the art's origins and techniques to the practical
The ultimate Instructor Series teaching tool for instructors who want to expand their curriculum!
Single-weave uniform is 15 oz. and constructed from 100% cotton. It features reinforcement on key stress points and a tapered body and sleeves for a close fit. The pants include a drawstring waist and reinforced knees. Imported.
Sizes: 150
Super strong 1 1/2 inch elastic waistband with heavy duty drawstring. Reinforced 1 inch elastic cuffs with 3 1/2 inch gusset for a complete custom fit. Distinctive Panther silhouette screenprint. Color: Black Sizes: A
Matt Thornton began training in Brazilian Jiu-Jitsu in 1988 and has been teaching BJJ full time for the past 15 years. Matt has taught all over the world including Africa, Iceland, Sweden, Germany, and many more.
Volume 1: Guard Top
This form fitting short-sleeve rash guard is constructed of polyester and spandex with a crew-cut neck and raglan sleeves to allow a full-range of motion. Features FlowMotion, a moisture-wicking technology that helps keep you cool, dry, and comforta
This form fitting long-sleeve rash guard is constructed of polyester and spandex with a crew-cut neck and raglan sleeves to allow a full-range of motion. Features FlowMotion, a moisture-wicking technology that helps keep you cool, dry, and comfortab
Each rash guard features flat stitching in a contrasting color thatincreases durability and prevents uncomfortable friction during training.Raglan sleeves allow an uninhibited, full range of motion with the UFC logoon the front left chest.
This long-sleeved rash guard features raglan sleeves that allow a full range of motion with a prominently displayed UFC logo on the front left chest. The unique, contrast-colored stitching creates a flat, durable seam that prevents uncomfortable fric
This single-weave uniform is constructed of a cotton/polyester blend. The approximately 14 oz jacket uses a grained cloth on top with a double diamond cloth on the bottom half. Features five rows of stitching on the lapel and down the back with reinf


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Match the silly faces to reveal a picture puzzle.
Choose the correct answer to power your car.
You can create a new game for your friends to join.
Protect your star station from a meteor shower.
Fight off tanks with the power of division.
Quickly handle math equations to blow invading aliens out of the sky.
Protect the robot from a blob of green slime.
Practice parts of speech.
Test your knowledge of American state capitals.
Match the missing letters to the correct word coconut.
Whack the moles on the head if you dare, but don't be surprised if they don't take it too kindly.
Help the tomatoes escape the dreaded salad! Bounce them across the kitchen to the table.
Show your stuff without even getting cold and wet! Hit the jumps and do tricks to score points.
Practice your skills as a race car driver by steering away from other cars and avoiding potholes and collisions.
Make at least 10 baskets before time runs out, and you're on your way to being a basketball star.
Save the Universe from Goobers. The more you hit, the more points you earn.
Help this poor guy look his best by selecting clothing items and putting them on his body.
Guide the chicken safely across roads and rivers, and earn worms. Each new level get tougher.
Drag the bubble wand to blow a bubble around a bug. The more bugs you capture, the more points you get.


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Story highlights
English champion Manchester City posts loss of $158 million for 2011-12 season
Its revenues rose to a record $374 million after winning title and playing in Champions League
Owner Sheikh Mansour bin Zayed injected $273 million to keep the club debt free
City paid more than $325 million in player wages -- the first English club to reach that level
Big-spending English club Manchester City moved a step closer to meeting European football's financial fairplay requirements on Friday despite posting a loss of almost $160 million for last season.
City's deficit of £97.9 million ($158 million) for 2011-12's Premier League-winning campaign was just under half that of the £197.5 million ($318 million) for the previous period – which was the biggest loss in soccer history.
The latest figure represents the fourth highest deficit in the English game – three of which belong to City since the arrival of its Abu Dhabi owners in 2008.
It can be contrasted with the $37 million net profit made by rival Manchester United in 2011-12.
United posted a reduced revenue of £320 million ($517 million) for that period, while City closed the gap with a club-record turnover of £231.1 million ($374 million). Both are substantially behind leading Spanish clubs Real Madrid and Barcelona.
Chelsea boosted by first profit in Abramovich era
It was the first time that City had breached the £200 million ($323 million) mark, and reflects the club's attempts to become more self-sufficient and avoid possible punishment from UEFA for failing to meet FFP targets.
However, owner Sheikh Mansour bin Zayed still injected £169 million ($273 million) in order to keep the club debt free.
"It is important to recognise the personal and ongoing influence of Sheikh Mansour bin Zayed on the rapid transformation that is taking place," said chairman Khaldoon al-Mubarak.
"The hard work of everyone involved at Manchester City over the last four years has begun to create an obvious momentum."
Last season City won the English title for the first time since 1969, and made a debut appearance in the UEFA Champions League.
Manchester United seeks to cash in as sponsor DHL is sent packing
The club's revenue would have been higher if not for a group-stage exit from Europe's top club competition – which has been repeated already this season – but new chief executive Ferran Soriano was satisfied with the results.
He joined City in September, having previously helped transform the financial fortunes of Barcelona between 2003-08.
"What I have found is a club on the verge of a historic transformation, reinforced by a genuine commitment to doing things well. It is a club with a rich history and the potential for an even brighter future," he said.
With the FFP rules coming into play from next season, City officials are under pressure to conform – or face the possible expulsion from European competition and a withholding of prize money.
A 10-year stadium rights deal with Etihad Airlines – owned by Abu Dhabi's royal family – which also includes the club's under-construction campus has considerably boosted City's balance sheet.
It is building an academy to try to avoid paying over the odds for star players in the future – the £201.8 million ($326 million) wage bill for 2011-12 made City the first English club to break £200 million in salaries, according to the Sporting Intelligence website. That equates to more than $890,000 a day.
"The City Football Academy will strengthen the club's youth development and training capabilities, enable more players to move through the Academy and Elite Development Squads into the first team in the future, while bringing all of the club's operations together on a single site within the Etihad Campus," Khaldoon said.
"The responsibility lies with all of us to continue the hard work that will ensure that this is only the beginning of a long and successful era for Manchester City."


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- Gnomish Poultryizer
- Item Level 68
- Binds when equipped
- Trinket
- +45 Stamina
- Requires Engineering (340)
- Use: Turns the target into a chicken for 15 sec. Well, that is assuming the transmogrification polarity has not been reversed...
- Cooldown: 5 min
While there was little success at the Porkulator and the Lambinator projects, the Poultryizer was a wild success. The eggs were just a bonus.
While tradeable, this item does require Gnome Engineering specialization to use.
This item is created at an anvil by Engineers specializing in Gnome Engineering, and with a skill level of 340 or greater.
|2x [Hardened Adamantite Tube]
|2x [Khorium Power Core]
|10x [Arcane Dust]
|2x [Large Prismatic Shard]
The Schematic for this trinket is learned at 340 Engineering skill from the Gnome Engineering trainers:
- Tinkmaster Overspark <Master Gnome Engineer> in Tinker Town in Ironforge
- Oglethorpe Obnoticus <Master Gnome Engineer> in Booty Bay in Stranglethorn Vale.
You must have a Gnome Engineer Membership Card to access this secret schematic.
- The casting time for the effect is Instant.
- The device has a 30 yard range.
- The effect is called Poultryized! and says "Cannot cast spells and damage is reduce by 66%." The effect is broken by any damage.
- It has a 5 minute cooldown and has a chance to backfire, as many engineering devices do, turning the caster into a chicken.
- As with all polymorph effects, Druids can shape shift out of it trivially.
- While there might be a small market for this item, anyone who can use it is able to make it.
- The polymorph effect cannot be used in Arena PvP Battles, though the Stamina bonus still applies.
Component Breakdown
- 2x Hardened Adamantite Tube
- 6x Hardened Adamantite Bar
- 60x Adamantite Bar
- 120x Adamantite Ore
- 60x Adamantite Bar
- 6x Hardened Adamantite Bar
- 2x Khorium Power Core
- 6x Khorium Bar
- 12x Khorium Ore
- 2x Primal Fire
- 6x Khorium Bar
- 10x Arcane Dust
- 2x Large Prismatic Shard
External links
Community content is available under CC-BY-SA unless otherwise noted.


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CTC takes key role in 'Cycle Yorkshire' legacy launch
CTC takes key role in 'Cycle Yorkshire' legacy launch
CTC is working with 'Welcome to Yorkshire' and York City Council on 'Cycle Yorkshire', an initiative to ensure that there is a 10-year legacy with a continued growth in cycling long after the banners have been taken down from the Tour de France route.
Teachers and pupils at Kettlethorpe High School were the first to take a look at Cycle Yorkshire's Tour de France schools' resource pack, as well as chat to the new British NFTO (Not For The Ordinary) Team members Dean and Russell. The pack is aimed at 7-14 year-olds to inspire them to cycle more often.
It's really given me a chance to map out how CTC is committed to inspiring people to cycle and promote the projects we can deliver for effective change."
Ginny Leonard
CTC Development Officer
Key to achieving this vision is ensuring that future generations of cyclists understand the benefits of cycling and have access to the skills, facilities and equipment to cycle confidently and safely, wherever they are. It is hoped that the 'Tour de France: Yorkshire Grand Départ, 2014 Resource Pack' will help to bring cycling to a new and younger audience.
CTC Development Officer Ginny Leonard is part of the team that is driving the legacy in Yorkshire and is pleased to be implementing CTC's core values and projects into the 10-year strategy.
To download the education pack for free please visit: